But bro the solvent present in plasma is mainly water and it's density is 1g/mL Hence, for water 1kg=1L Therefore, it shouldn't matter whether it's mOsm/kg or mOsm/L.....
I didn’t arrive at anything. It’s written in the textbook. These 3 substances (Na, Glucose, and Urea) are the most significant when it comes to osmosis.
Med-tech here. We do have to know how to "manually" calculate osmolality and not just by instrument measurement as the doctor joked. Urea is a small polar molecule like ethanol that affect osmolality. Polar molecules and ions are the biggest contributing players and everything else plays a very minor role when considering osmolality. The equation multiples sodium by 2 to account for all ions in the body and then the the next polar substances, glucose and urea. The equation most med-techs should be familiar with is 1.86Na + (glu/18) + (bun/2.8) + 9. This equation is more precise when osmolality is measured in lab which is by freezing point depression.
It’s not as abundant as sodium (for example). It’s a drop in a bucket! The equation cannot take everything into account, it’s just a very quick way of assessing serum osmolality until the lab results (measured osmolality) come back.
@@MedicosisPerfectionalis wow. thank you for replying! your channel is very helpful :) I guess it got a bit confusing bc i always read albumin=oncotic pressure, maybe that's just true when you're only talking about proteins. 🤔
i had the same question. I couldn't find much but what i did find was saying that by dividing by 18 and 2.8 allow the units to be converted to mmol/kg or mmol/L. I'm not too sure either.
it's from the transformation of mg/dL of Glucose (physiologically between 70-110 mg/dL) in mmol/L or mOsm/L (because glucose doesn't dissociate in plasma, from here we can deduce that mmol and mOsm of glucose are the same), and the transformation of BUN (blood urea nitrogen) from mg/dL (physiologically between 7-20 mg/dL) in mmol/L or mOsm/L (same explanation as for glucose). You divide it by 28, because nitrogen is a diatomic molecule and it's molar mass it's 14 g/mol
Great video as always!! am planning to finish the whole list today hopefully haha mmm about the question at the beginning of the vid.. if the dude adds 100% of water to a patient --- wouldn't that also cause a decrease in Na levels!...so i just checked ur sodium&water vid n u said it's not that Na decreased but just increase in total body water levels..🤔 but isn't that the case with hyponatremia wich can be caused by excess amount of where Na levels becomes >135mmol/L?!😕
Hei, let me answer the question. If the dude give 100% of water instead of saline water to the patient, it will lead to DECREASE THE CONCENTRATION OF SODIUM, but THE NATRIUM LEVEL STILL SAME. Let me give you an example. Before the dude give 100% water to the patient, TOTAL BODY SODIUM ARE 10. Then, after the dude give 100% water. THE TOTAL BODY SODIUM STILL 10. THE CONCENTRATION of SODIUM will DECREASE, but THE TOTAL BODY SODIUM STILL SAME. Hope my answer help you, 😃😃😃😃
Though old vid!... b4 even go forward Students are not stupid😠 All health professionals started as students .... and no one goes to practise while majoring in economics or arts! Students make mistakes that's y we provide them with supervisors 😦☹
@@MedicosisPerfectionalis it was meant as a joke... keeps me on my toes... thanks for the uploads... its helping me in clinical chemistry and coagulation right now!!
I will send these videos to my professors, they need to simplify things...
No one should be called "Stupid"! Thanks for the video
You're a great mentor
Thanks, dear :)
Why did you change 18 to 20 and 2.8 to 3? Shouldn’t formula not be changed?
Stay as brilliant as u are💜
Thank you 🙏
Where from did we get 18 below glucose and 2.8 below BUN?
HousTEN we have a problem. Thank you!
but how come the osmolality is calculated in mosm/L ?
It’s mOsm/Kg but it doesn’t matter clinically or practically.
But bro the solvent present in plasma is mainly water and it's density is 1g/mL
Hence, for water 1kg=1L
Therefore, it shouldn't matter whether it's mOsm/kg or mOsm/L.....
@@shreekitchen4535 thanks alot
Was about to ask the same thing
How did you arrive at that equation for calculated osmolality?
I didn’t arrive at anything.
It’s written in the textbook.
These 3 substances (Na, Glucose, and Urea) are the most significant when it comes to osmosis.
Med-tech here. We do have to know how to "manually" calculate osmolality and not just by instrument measurement as the doctor joked. Urea is a small polar molecule like ethanol that affect osmolality. Polar molecules and ions are the biggest contributing players and everything else plays a very minor role when considering osmolality. The equation multiples sodium by 2 to account for all ions in the body and then the the next polar substances, glucose and urea.
The equation most med-techs should be familiar with is 1.86Na + (glu/18) + (bun/2.8) + 9. This equation is more precise when osmolality is measured in lab which is by freezing point depression.
I’m not going to say it because I’m a good person😂😂
😁😁😁
Great and easy
Thank you 😊
Very Great Teaching
Thank you!
Very nice
Thank you
My pleasure 😇
Thank you 💚
at 0:22 seconds i drive that road to get home to the desert :) every day
Wow! Is that right?
Thank you so much
If glucose is 720mg% how do you convert this unit?? Correct Conversion of this unit???
720 mg% = 720 mg/dl. Is this what you wanted?
or did you want to convert to mmol/L?
Why is albumin not included in the formula? Isn't it the major cause of oncotic pressure? I'm a bit confused. Hope someone can answer.
It’s not as abundant as sodium (for example). It’s a drop in a bucket!
The equation cannot take everything into account, it’s just a very quick way of assessing serum osmolality until the lab results (measured osmolality) come back.
@@MedicosisPerfectionalis wow. thank you for replying! your channel is very helpful :) I guess it got a bit confusing bc i always read albumin=oncotic pressure, maybe that's just true when you're only talking about proteins. 🤔
All should be converted to SI units rite?
What do you mean?
I don’t understand
Sodium should be in mmol/L
Glucose should be in mg/dL
BUN in mg/dL
Correct?
What about urine osmolarity???plzz reply
shouldnt calculated osmolality be mOsm/kg isntead of mOsm/L??
Theoretically, yes. Clinically, it doesn’t matter.
where did the 18 and 2.8 taken from?
i had the same question. I couldn't find much but what i did find was saying that by dividing by 18 and 2.8 allow the units to be converted to mmol/kg or mmol/L. I'm not too sure either.
it's from the transformation of mg/dL of Glucose (physiologically between 70-110 mg/dL) in mmol/L or mOsm/L (because glucose doesn't dissociate in plasma, from here we can deduce that mmol and mOsm of glucose are the same), and the transformation of BUN (blood urea nitrogen) from mg/dL (physiologically between 7-20 mg/dL) in mmol/L or mOsm/L (same explanation as for glucose). You divide it by 28, because nitrogen is a diatomic molecule and it's molar mass it's 14 g/mol
@@jesusrico2170 yes you're right
"you gotta watch these videos first but I wont link to them"
1:14 I died😂
Great video as always!! am planning to finish the whole list today hopefully haha
mmm about the question at the beginning of the vid.. if the dude adds 100% of water to a patient --- wouldn't that also cause a decrease in Na levels!...so i just checked ur sodium&water vid n u said it's not that Na decreased but just increase in total body water levels..🤔 but isn't that the case with hyponatremia wich can be caused by excess amount of where Na levels becomes >135mmol/L?!😕
Hei, let me answer the question.
If the dude give 100% of water instead of saline water to the patient, it will lead to DECREASE THE CONCENTRATION OF SODIUM, but THE NATRIUM LEVEL STILL SAME.
Let me give you an example.
Before the dude give 100% water to the patient, TOTAL BODY SODIUM ARE 10.
Then, after the dude give 100% water. THE TOTAL BODY SODIUM STILL 10.
THE CONCENTRATION of SODIUM will DECREASE, but THE TOTAL BODY SODIUM STILL SAME.
Hope my answer help you, 😃😃😃😃
Thanks. But I have a problem I can not find answer to this..What is the relationship between ratio and osmolality in iodinated contrast media?
What?
Thanks!
My pleasure 😇
I burst out laughing in OSMOLARITY= LITREEEEEEEEEEEEEE HAHAHHAHAHAHAHAHAH
Thank
how to calculate osmolarity of 5% dextrose in normal saline
It will be very close to the plasma osmolality (maybe a little higher).
They have to give you the numbers
Though old vid!... b4 even go forward
Students are not stupid😠
All health professionals started as students .... and no one goes to practise while majoring in economics or arts!
Students make mistakes that's y we provide them with supervisors 😦☹
looks like utah?
❤❤❤❤❤❤❤❤
Thank you!
when he said these lab technicians are mediocre..... and i took that personally... LOL
Haha 🤣
I am sorry!
I make fun of doctors too :)
Just joking 🙃
@@MedicosisPerfectionalis it was meant as a joke... keeps me on my toes... thanks for the uploads... its helping me in clinical chemistry and coagulation right now!!
Thank you 🙏
Could not complete the video because of your condescending comments on the medical student! you should not call any one stupid!