This is marrying together the mutations theory/ stochastic theory with the stem cell hypothesis. If that was the case, then do stem cells develop mutations to give them embryonic stem cell markers on them and embryonic stem cell capabilities? Wow.
Acquiring stemness in a tumour context largely depends on pluripotent transcription factors secreted from the surrounding stem cell niche, plus epigenetic regulation plays a huge role (which Of course can be influenced by regular DNA mutations)
@@robbiedeacon9412 Is it about acquiring stemness in a tumor context? If the whole tumor wouldn't arise without cancer stem cells (and the science points in this direction) then the basis is a nocebo effect. A person reacting to some ideas that give rise to physical reaction. So while the person continues to uphold such ideas / beliefs then no treatment is going to work because it is not a matter of not killing the cancer stem cells. No cells would survive the chemo or directed radiation. What happens is the person's reaction regrows the tumor. So it is the ideas / beliefs that need to be eradicated. Then the body will do the spontaneous remission of the cancer. Ah, but there's no money in that!
This is marrying together the mutations theory/ stochastic theory with the stem cell hypothesis. If that was the case, then do stem cells develop mutations to give them embryonic stem cell markers on them and embryonic stem cell capabilities? Wow.
Acquiring stemness in a tumour context largely depends on pluripotent transcription factors secreted from the surrounding stem cell niche, plus epigenetic regulation plays a huge role (which Of course can be influenced by regular DNA mutations)
@@robbiedeacon9412 Is it about acquiring stemness in a tumor context? If the whole tumor wouldn't arise without cancer stem cells (and the science points in this direction) then the basis is a nocebo effect. A person reacting to some ideas that give rise to physical reaction. So while the person continues to uphold such ideas / beliefs then no treatment is going to work because it is not a matter of not killing the cancer stem cells. No cells would survive the chemo or directed radiation. What happens is the person's reaction regrows the tumor. So it is the ideas / beliefs that need to be eradicated. Then the body will do the spontaneous remission of the cancer. Ah, but there's no money in that!