Center for Genetic Medicine
Center for Genetic Medicine
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"Genes and Variants That Influence Common Metabolic Diseases" with Karen Mohlke, PhD
Karen Mohlke, PhD, is professor and associate chair of Genetics, and the Oliver Smithies Investigator at the University of North Carolina.
This lecture was part of the Scott Lecture Series, an educational event co-sponsored by Northwestern University's Center for Genetic Medicine and Driskill Graduate Program in Life Sciences.
Recorded on: September 7, 2023
Переглядів: 80

Відео

"Genetic Mechanisms of Autoimmune Diseases" with Soumya Raychaudhuri, MD, PhD
Переглядів 1,8 тис.Рік тому
Soumya Raychaudhuri, MD, PhD, is a professor of Medicine and of Biomedical Informatics at Harvard Medical School. He is also the Coblyn and Brenner Distinguished Chair in Immunology, the director of the Center for Data Sciences at Brigham and Women’s Hospital, and institute member at the Broad Institute. This lecture was part of the Scott Lecture Series, an educational event co-sponsored by Nor...
"The Chromosomal Basis of Sex Differences in Health and Disease" with David Page, MD
Переглядів 583Рік тому
David Page, MD, is professor of Biology at Massachusetts Institute of Technology, a Whitehead Institute member and Howard Hughes Medical Institute investigator. This lecture was part of the Scott Lecture Series, an educational event co-sponsored by Northwestern University's Center for Genetic Medicine and Driskill Graduate Program in Life Sciences. Recorded on: March 9, 2023
Almost Human: How New Discoveries from South Africa Change Our View of Human Origins
Переглядів 77 тис.Рік тому
Human evolution was once thought to be a straight march of progress, but both ancient DNA and new fossil discoveries are showing how unexpected populations have contributed to our origins in surprising ways. The recent discovery of a huge trove of fossil bones in the Rising Star cave system of South Africa has identified a new ancestral form of human, Homo naledi, that surprised scientists arou...
Evolution: The Impact of Social and Political Concerns on Science - Eugenie Scott & Robert Pennock
Переглядів 321Рік тому
Evolution is a complex and controversial subject with profound scientific, educational and legal implications. Two experts provide different perspectives: Eugenie C. Scott, executive director of the National Center for Science Education, addresses the political and social issues challenging the science classroom. Robert T. Pennock, professor of History, Philosophy and Sociology of Science at Mi...
The Science and Politics of Stem Cells, Aging and Cancer with Sean Morrison, PhD - Oct. 17, 2007
Переглядів 124Рік тому
Sean Morrison, PhD, discusses the basics of stem cells, the roles that stem cells play in cancer and aging and the ways in which state and federal politics have impacted stem cell research. Morrison is associate professor at University of Michigan Medical School, director of University of Michigan's Center for Stem Cell Biology and investigator at the Howard Hughes Medical Institute. This lectu...
Race, Genetic Ancestry and Disease with Rick Kittles, PhD - Nov. 16-17, 2004
Переглядів 289Рік тому
Rick Kittles, PhD, associate professor of Molecular Virology, Immunology and Medical Genetics at the Ohio State University Medical Center, explains how DNA is used to trace African-American ancestry and how genetics can affect complex traits and diseases such as prostate cancer, personality traits and skin color. This lecture was part of the Silverstein Lecture Series, an educational event host...
Building a New Biology with Drew Endy, PhD - Oct. 27, 2008
Переглядів 115Рік тому
Drew Endy, PhD, assistant professor of Bioengineering, Stanford University, discusses powerful new technologies that allow life to be built from scratch. New engineered organisms are being constructed to help cure cancer, produce renewable energy and assemble living computers. But who will control these new biotechnologies? This lecture was part of the Silverstein Lecture Series, an educational...
Personal Genomes and Web 2.0 Volunteerism with George Church, PhD - May 12, 2009
Переглядів 219Рік тому
Do genes help predict disease, help you decide on insurance or help scientists discover your family traits? Can we work together to make a bio-weather map, tracking pathogens and allergens around the globe? Is a microscopic flake of skin from a crime scene enough to determine a name, a face and a psychiatric profile? George Church, PhD, professor of Genetics at Harvard Medical School, explores ...
The Biologic Basis of Obesity with Jeffrey Friedman, MD, PhD - Oct. 13, 2010
Переглядів 423Рік тому
Jeffrey Friedman, MD, PhD, the Marilyn M. Simpson Professor and head of the Laboratory of Molecular Genetics at The Rockefeller University, discusses what his team learned about the biological processes that regulate weight and appetite and how further research could lead to a better understanding of obesity. This lecture was part of the Silverstein Lecture Series, an educational event hosted b...
From Reading to Writing Life Code with Juan Enriquez, PhD - Nov. 4, 2009
Переглядів 40Рік тому
Juan Enriquez, PhD, managing director of Excel Venture Management and accomplished writer, businessman and academic, explores what is possible using genome technology and how it stands to revolutionize our lives. This lecture was part of the Silverstein Lecture Series, an educational event hosted by Northwestern University's Center for Genetic Medicine. Learn more: cgm.northwestern.edu/educatio...
TEDxNorthwesternU: Identity, Democracy After Anatomy with Alice Dreger, PhD - Dec. 15, 2010
Переглядів 16Рік тому
As our democracy has matured, it has still retained an ancient reliance on anatomy as deeply meaningful. Yet at the same time, science has been dissolving the bright lines between anatomical categories. So what's next? Alice Dreger, PhD, discusses what could and what will democracy look like after anatomy? Dreger is professor of Clinical Medical Humanities and Bioethics, Northwestern University...
Genes From the Fountain of Youth with Cynthia Kenyon, PhD - May 11, 2011
Переглядів 378Рік тому
Aging is actively controlled by genes. All animals, and possibly humans, too, seem to have the potential to live much longer than they normally do. Cynthia Kenyon, PhD, explores the mechanisms by which the rate of aging can be slowed down. Kenyon is distinguished professor of Biochemistry and Biophysics, American Cancer Society Research Professor and director of the Hillblom Center for the Biol...
Identity, the Biology of Race in the Absence of Biological Races with Rick Kittles, PhD
Переглядів 63Рік тому
Defining "race" continues to be a nemesis. Knowledge from human genetic research is increasingly challenging the notion that race and biology are inextricably linked, engendering tremendous ramifications for human relations, identity and public health. Rick Kittles, PhD, discusses why using race in biomedical studies is problematic using examples from U.S. groups that transcend "racial" boundar...
Drug Abuse: A Family Matter? with Glen R. Hanson, PhD, DDS - October 26, 2011
Переглядів 54Рік тому
Scientists have determined that the prevalence of inheriting drug abuse ranges from 40 to 60 percent, suggesting that vulnerability to drug addiction is not merely environmental, but also genetic. Hanson, professor of Pharmacology and Toxicology at the University of Utah and former director of the National Institute on Drug Abuse, explores the genetic elements of drug abuse. This lecture was pa...
Rethinking Mental Illness with Thomas R. Insel, MD - March 6, 2012
Переглядів 64Рік тому
Rethinking Mental Illness with Thomas R. Insel, MD - March 6, 2012
Personal Genome Sequencing with Marc S. Williams, MD - Jan. 16, 2013
Переглядів 27Рік тому
Personal Genome Sequencing with Marc S. Williams, MD - Jan. 16, 2013
Endocrine Disrupting Contaminants and Reproductive Health: Alligators as Canaries in a Coal Mine
Переглядів 64Рік тому
Endocrine Disrupting Contaminants and Reproductive Health: Alligators as Canaries in a Coal Mine
"Cancer Stem Cells: Are We Targeting the Right Cells?" with Max S. Wicha, MD - May 21, 2014
Переглядів 608Рік тому
"Cancer Stem Cells: Are We Targeting the Right Cells?" with Max S. Wicha, MD - May 21, 2014
"Telomeres, Telomerase and Association with Human Disease" with Thomas Cech, PhD - April 5, 2011
Переглядів 207Рік тому
"Telomeres, Telomerase and Association with Human Disease" with Thomas Cech, PhD - April 5, 2011
"Resetting Metabolism: Nuclear Receptors and AMPK" with Ronald Evans, PhD - June 1, 2010
Переглядів 190Рік тому
"Resetting Metabolism: Nuclear Receptors and AMPK" with Ronald Evans, PhD - June 1, 2010
"Return to RNAi World: Rethinking Gene Expression, Evolution and Medicine" with Craig Mello, PhD
Переглядів 229Рік тому
"Return to RNAi World: Rethinking Gene Expression, Evolution and Medicine" with Craig Mello, PhD
"Using Simple Cells to Unlock Complex Secrets of Biology" with Susan Lindquist, PhD - March 27, 2007
Переглядів 50Рік тому
"Using Simple Cells to Unlock Complex Secrets of Biology" with Susan Lindquist, PhD - March 27, 2007
Small Game Hunting: Microbial Diagnostics, Surveillance and Discovery in Acute and Chronic Diseases
Переглядів 1066 років тому
Small Game Hunting: Microbial Diagnostics, Surveillance and Discovery in Acute and Chronic Diseases
Race, Genetic Ancestry and Disease
Переглядів 2,7 тис.9 років тому
Race, Genetic Ancestry and Disease
The Science and Politics of Stem Cells, Aging, and Cancer
Переглядів 3419 років тому
The Science and Politics of Stem Cells, Aging, and Cancer
Evolution: The Impact of Social and Political Concerns on Science
Переглядів 479 років тому
Evolution: The Impact of Social and Political Concerns on Science
Personal Genomes and Web 2.0 Volunteerism
Переглядів 839 років тому
Personal Genomes and Web 2.0 Volunteerism
Building a New Biology
Переглядів 6279 років тому
Building a New Biology
From Reading to Writing Life Code
Переглядів 3579 років тому
From Reading to Writing Life Code

КОМЕНТАРІ

  • @Lance_Lough
    @Lance_Lough 19 днів тому

    Misleading. The main heading says: 1 year ago. This is from 2017-seven years old.

  • @zigavojska1672
    @zigavojska1672 3 місяці тому

    we are geneticaly modified from time to time by aliens. maybe Naledi excavated this cave and they had oil lamps

  • @BeccaL2016
    @BeccaL2016 3 місяці тому

    this is better than Netflix, more educational. I think some sort of animals (possible snake like) had hurt those beings and dragged them into the cave remote area to store food..it's just that simple?? Some of them may not die when they hunt and store them there..

  • @Ashitsuingami
    @Ashitsuingami 3 місяці тому

    the evidence of curiosity, finding use, and possibly protection. mammals have lived underground before

  • @saveriosalemme5366
    @saveriosalemme5366 3 місяці тому

    I bet Homo Naledi was not the first of the homo family to have used the Dineledi cave system. If they were to dig deeper into the topsoil I’m sure they could be in for a big surprise.

  • @JungleJargon
    @JungleJargon 4 місяці тому

    We came from being created. The question is how we got created. Since no physical thing can ever make or direct itself, the cause cannot be physical. That is the science.

  • @RulgertGhostalker
    @RulgertGhostalker 4 місяці тому

    oh that's what went wrong, nat geo was there. well, I guess I have some angst with the one nat geo heroin addict production dude, going to the tribes with a load of crap, but like he's some self proclaimed authority. it's not funny.

  • @RulgertGhostalker
    @RulgertGhostalker 4 місяці тому

    how long did it take to get the H. on Neanderthalensis ? but Naledi gets the H. almost as if by default ? ...I would say H ? Naledi ...I don't think we are there yet with this. the big picture is strewn with just so many failed attempts at bipedal evolution, as an extremely messy littering from the trees .... Sima de los Huesos is H ? antesessor, likely an african overshoot Gibraltar crosser....same complete mess as Naledi, but dramatically separated in time................where H.Neanderthalensis -- > *Did What Makes Sense* < --- Under Population Overshoot Conditions, ( had fewer off spring ) I would put the H on Neanderthalensis, and more tend to lump Naledi in with Antecessor. everyone alive today has learned to overshoot, with the overshoots, to survive the overshoots. . so don't stick your head in the sand when I say this --> that's not going to work this time. I mean could you imagine sub-saharans on a space station? ....they would be knowing on each other's bones as the life support systems failed.....they breed faster than the food grows, and think it should be ok that they don't cooperate with census work <---- That Is NOT " ok". in fact, the anthropological definition of cannibal is synonymous with sub-saharan genetics on small islands.....bad news, our planet is like an island. but the failure of all humanity has always been approaching them with reasoning, because that's just handing them everything they need to know to continue converting the entire planet's biomass into them, without anyone finding out about it until the next time. I submit the hypothesis that the Dineledi Chamber was a repository of cannibal scraps.

  • @kp6215
    @kp6215 5 місяців тому

    You should have more views most important that I have tried to keep up as this is what U Tube and internet was to bring education to everyone. 😊

  • @SuperRickflick
    @SuperRickflick 6 місяців тому

    I wonder why the explorers didn't widen the tunnel into the cave so that more people could get in?

  • @dans9206
    @dans9206 7 місяців тому

    I was just wondering if the photograph of the vice president of South Africa was taken before or after chants or songs calling for the death of white farmers?

  • @michaelgonzalez9058
    @michaelgonzalez9058 9 місяців тому

    U dont know hell until u pissoff GOD

  • @Rico-Suave_
    @Rico-Suave_ 11 місяців тому

    Watched all of it 1:06:47

  • @kenhuang1045
    @kenhuang1045 Рік тому

    Almost Human Is and Will NEVER Be Genuine Homo sapien . Period.

  • @martylawrence5532
    @martylawrence5532 Рік тому

    Neanderthals and Denisovans were human with mere modifications to their gene expression without evolution's evolving of any DNA mutations. They were 99.84% identical to us as we are 99.90% identical to each other. Subtract the thousands since we co-existed, then we would have been 99.90% to each other back then. This means there are no people on earth sharing '4% to 6%' of their DNA! If my cousins shared 4% to 6% of their DNA with your cousins then how can they be 99.90% identical, as all humans are, at the same time? No. To be truthfully informative, it is a sharing of GENE EXPRESSIONS MODIFICATIONS, not DNA. The DNA does not alter with new/old gene expression. The gene expression are 4% to 6% similar with the Neanderthals and Denisovans. These epigenetics coming from the epigenome is a SECOND INFORMATION CODE RUNNING OVERTOP THE DNA. It works like a software program! This all has a signature of intelligent design...not Godless-spinned evolution. There is no pertinence in evolution here. It's all smoke and mirrors. It's all gaslighting. We are an intelligent design, not a random design by evolution and natural selection. Evidence? Easy! ALL life has an inbuilt epigenome that takes cues from the environment for all of the classic adaptations we see...such as the Darwin Finch with their different beak shapes. Or cinclid and stickleback fish. Much, not all, of antibiotic resistance. High altitude breathing. Cancer becoming resistant to treatments are caused largely by its epigenome making modifications of its genes. The actions of the epigenome is called epigenetics. These are post-2014 materially founded facts. Evolution is NOT happening. The intelligent designer I mentioned? Jesus Christ beyond doubt.He gives much more than the fabled evolutionary theory. Jesus offers eternal forever life if you call upon his name and believe he will do it for you. It's 100% grace by faith, no merit on your part...present or future...is needed. It is FREE gift because he sacrificed himself on the cross to take on YOUR sin onto his body and gives YOU his 100% perfection in exchange. You cannot go to hell even if try when you receive this free gift. So much better than the theory of evolution offers!

  • @je-freenorman7787
    @je-freenorman7787 Рік тому

    Mumbo Jumbo

  • @jimmyjasi-
    @jimmyjasi- Рік тому

    Good job

  • @MrBlaqgold
    @MrBlaqgold Рік тому

    A brilliant and underrated lecture.

  • @briemills9209
    @briemills9209 Рік тому

    I don't believe Naledi shuld be classifed as 'Homo". I elieve they were Australopithecines. Other than similar teeth and being bipedal, what makes them a member of our genus?

  • @HL-qv3yd
    @HL-qv3yd Рік тому

    Need to hurry up found the way kill cancer stem cells cure, people dying.

  • @garymacmillan
    @garymacmillan Рік тому

    I never tire of hearing a presentation on this amazing discovery and it will keep giving for years and years.

  • @emilianomendez8295
    @emilianomendez8295 Рік тому

    RNA world is cringe

  •  Рік тому

    7 (seven) Considerations for two simple questions. Whereas (1) THAT, in a rare event, several fossils were found gathered in the same place; (2) THAT, these fossils are of individuals with ages ranging from months (infant) to mature age; (3) THAT these individuals appear to have died at the same time; (4) THAT there are no traces of food or hunting utensils/tools - nor of routine use of fire, although the place is very dark; (5) THAT the site is difficult to access even for small individuals, being difficult to go down to the lower chambers of the cave; (6) that exit from the site must be via the entry point; (7) that transporting adult corpses through the narrow labyrinth would be especially trying. I ASK: Wouldn't these individuals belong to a group (complete family, with adults, young people and children) that, in a hurry, sought refuge in the depths of the cave when fleeing from a pursuer who, in turn, had the means to understand the situation and set up guard for days or weeks, until it kills the refugees with thirst and hunger? Could the stalker be sapiens?

    • @mm4853
      @mm4853 3 місяці тому

      They did find charcoal and burnt animal bones.

    •  3 місяці тому

      @@mm4853 What they actually found is generating a lot of academic discussion, as it seems that they jumped to some "conclusions".

  • @grahamgillard3722
    @grahamgillard3722 Рік тому

    Why would they crawl into the cave? In darkness? Something doesn’t add up. I think a geologist needs to study and document the geological history of the cave and surrounding area before the anthropologists, palaeontologists and archaeologists come up with their theories.

    • @mm4853
      @mm4853 3 місяці тому

      They did investigate the cave’s history and ruled out options how the bones could have gotten there.

  • @jimmyjasi-
    @jimmyjasi- Рік тому

    Great work. Long Live Genomic revolution! Long Live George Church and He Jiankui!

  • @trisld
    @trisld Рік тому

    Knowing that our ancestors at some point came out of the trees by necessity and became more and more upright, clearly naledi used their archaic arm and shoulder anatomy to climb easily in these caves. Then looking at the dichotomy of those features, juxtaposing their archaic with their more modern human characteristics, clearly there was interbreeding with early more modern humans that led to the skull, leg, foot and other traits being chosen for adaptivity. So imho the naledi are an excellent example of what an in-between species would be like, which is special since we have little direct sample to examine besides them. Erectus and habilus are obviously key in our development, but naledi gives us an idea what the 'blank areas' in the search thus far might have been like. In that respect the combo of both archaic and more modern human features are the ideal representation we needed to get a clearer picture. And with such abundant samples across age and gender, wow... Regardless of their relationship to us, we can see a species that exemplifies how evolution does its thing.

  • @davidallard1980
    @davidallard1980 Рік тому

    I have another question. Have you heard of Michael Cremo? He is a doctor that scoured all of the old academic papers and scientific journals to get a better understanding of where we come from. He found some pretty interesting things in the museum's oopart junk drawer. At 39:12 you say that is the only evidence we have of human ancestors prior to a million years ago? Well, merry Christmas, here is a list of finds that you didnt know about, and Dr Cremo talking about them.ua-cam.com/video/cazjCCi3Kpk/v-deo.html Please go back and DNA test these. Youre not supposed to ignore evidence as a scientist, even if it doesnt fit the story that youre taught to tell.

  • @davidallard1980
    @davidallard1980 Рік тому

    Why dont they just did the hole bigger?

  • @michaelparker7831
    @michaelparker7831 Рік тому

    It’s nice to hear a real scientist speak of “female” team members who are naturally smaller than men. I believe this scientist because he isn’t stuck on woke jargon.

  • @josephturner7569
    @josephturner7569 Рік тому

    Maybe it was a method of concealing the deceased from predators before inhumation was thought of. Perhaps their relatives dragged them in and then blocked the entrance.

  • @tequila6955
    @tequila6955 Рік тому

    Just think what we could accomplish scientifically if the funding we put towards war was put forth towards scientific discovery.

  • @rogerscottcathey
    @rogerscottcathey Рік тому

    Fine, but forget about messing with DNA. It's a foolish thing

  • @StrangersIteDomum
    @StrangersIteDomum Рік тому

    The future is female, come on guy. Balding pudgy ginger creeper.

  • @AreHan1991
    @AreHan1991 Рік тому

    Amazing. And John Hawks is an incredibly good communicator 👍🏾

  • @shadetreader
    @shadetreader Рік тому

    Taking 30 minutes to accomplish what Usain Bolt can do in 9 seconds is basically what living with chronic fatigue is like...

  • @smithdog4770
    @smithdog4770 Рік тому

    I can think of a more simple way for them to get there than "They put them there", which implies a high level of cognition, wouldn't they have had some form of tools on them by the way, if they were that smart? I think It's a "funnel trap". They were living in and around the cave, something in the cave was a source of food or shelter, etc. and once in a while they would get lost and end up going in the wrong direction until they gave up and died. Rather than assuming high intelligence in an animal with that small of a brain, it makes more sense to assume they were trapped by an oddly shaped cave. At best this might imply curiosity. Furthermore, the odd geography of the cave assured they would get so far down that they weren't prey to anything and this helped preserve them as well. I can think of one other possibility. They where put there by Humans or forced to flee down into the cave by humans who lit fires forcing them to flee and die. Or they were fleeing from forest fires without humans involved at all. But if the date comes back as contemporary to humans then it still makes more sense that if it was ritualistic, that it was humans who put them there. Those are two possibilities right off the top of my head that make more sense than the assumption that they were putting their dead way back in there.

  • @jamesn.economou9922
    @jamesn.economou9922 Рік тому

    It is also reasonable to assume, that some members, of this species, grew too large to enter the cave system. Just like today, with modern humans. Shaq, just aint going in.

  • @jamesn.economou9922
    @jamesn.economou9922 Рік тому

    Excellent lecture. I would suggest that the larger members of this population would not be represented here, due the size of the cave. The largest ones, if there were, would not fit into the tunnels.

  • @davenotdoug8394
    @davenotdoug8394 Рік тому

    Why don't they just widen the opening a fraction with a portable rock saw? Or a chisel and hammer?

  • @kennyw871
    @kennyw871 Рік тому

    Early on I was curious about the body size and the ability of the homo naledi people to fit inside the deeper chambers of the Rising Star Cave complex, which you did cover. Thank you for that. I'm also curious about the possible reasons these people had to ventured so far into the cave, especially considering the difficulty involved. Perhaps it was to escape larger predators that couldn't fit that far into the cave? Perhaps it was a safe place to keep scavengers away from the deceased? Apparently, you did not find evidence of soot on the cave ceilings, so how did they navigate in complete darkness and what did they do once inside? Did you find evidence of food consumption (smaller bones, seed pods, etc.)? It's possible they knew to consume bones for the calcium. Maybe we need a new branch of science called paleopsychology (my neologism) to address some of these issues? Safe to say, some of them, at the least, were not claustrophobic. Excellent presentation thank you.

    • @jamesn.economou9922
      @jamesn.economou9922 Рік тому

      This was a grave. Apparently, the ancient undertaker of the day, was tasked with dragging the body through that ridiculously small cave, most likely to keep it from larger animals. Im sure the flies found their way in.

    • @happyg.444
      @happyg.444 Рік тому

      I'd say they were more "nocturnal" back in the day, among other things. Possibly see a more expanded color spectrum.

    • @Hdtr564
      @Hdtr564 Рік тому

      Nuclear Fallout

  • @theatheistcat8081
    @theatheistcat8081 Рік тому

    He can do without the story of the two cavers, the narrow passages, etc. This has been retold elebenty billion times already.

  • @johnnyllooddte3415
    @johnnyllooddte3415 Рік тому

    chimps are our closest living relatives.. they are the true prehumans.. therefore homo sapiens and neandrathals are pre chimps.. we are homo sapien sapiens not homo sapiens

    • @antonijaume8498
      @antonijaume8498 Рік тому

      johnny lloddte, chimpanzees are rather para-humans, we have a common ancestor, however our lineages have diverged and we are in "parallel" lines. As for the taxonomic name it is not always stable, and has gone through changes, some of which have been wide ranging.

    • @jamesn.economou9922
      @jamesn.economou9922 Рік тому

      what? We split from chimps 6 million years ago. However we are about as related to them, that we are these guys. Homo Naledi. Naledi couldn't make it. Chimps did.

    • @JasS-hu6cf
      @JasS-hu6cf Рік тому

      @@antonijaume8498 we are in parallel lines but they branched off at an earlier stage of development, thus remained apes

  • @johnnyllooddte3415
    @johnnyllooddte3415 Рік тому

    neandrathals and homo sapiens are not humans.. they are hominins. . they went extinct 50,000 years before us.. calling them prehumans is an attempt to cause idiots to believe we are related.. we are homo sapien sapiens.. modern humans are less than 15,000 years old.. the oldest human dna is found in UK.. case closed

  • @Kyrani99
    @Kyrani99 Рік тому

    This is marrying together the mutations theory/ stochastic theory with the stem cell hypothesis. If that was the case, then do stem cells develop mutations to give them embryonic stem cell markers on them and embryonic stem cell capabilities? Wow.

    • @robbiedeacon9412
      @robbiedeacon9412 Рік тому

      Acquiring stemness in a tumour context largely depends on pluripotent transcription factors secreted from the surrounding stem cell niche, plus epigenetic regulation plays a huge role (which Of course can be influenced by regular DNA mutations)

    • @Kyrani99
      @Kyrani99 Місяць тому

      @@robbiedeacon9412 Is it about acquiring stemness in a tumor context? If the whole tumor wouldn't arise without cancer stem cells (and the science points in this direction) then the basis is a nocebo effect. A person reacting to some ideas that give rise to physical reaction. So while the person continues to uphold such ideas / beliefs then no treatment is going to work because it is not a matter of not killing the cancer stem cells. No cells would survive the chemo or directed radiation. What happens is the person's reaction regrows the tumor. So it is the ideas / beliefs that need to be eradicated. Then the body will do the spontaneous remission of the cancer. Ah, but there's no money in that!

  • @bootlegapples
    @bootlegapples Рік тому

    55:30 . I voted for Trump. Twice. You did however validate,again,my belief that leftism has perverted the sciences.Also there is no "THE" science but in political circles.I will continue to have an interest in anthropology and the sciences despite the current political snobbery.

  • @simvlacrvm
    @simvlacrvm Рік тому

    fix your audio

  • @robertjackson9326
    @robertjackson9326 Рік тому

    How thrilling. From the brave cavers who took extreme risks to discover a miraculous trove of hominin fossils to the equally brave female paleoanthropologists who excavated and helped explain them...a new member of our genus! There is much we may never know about our distant lineage...but we know measurably more now!

  • @stephengent9974
    @stephengent9974 Рік тому

    Absolutely fascinating and very exciting

  • @marktwain368
    @marktwain368 Рік тому

    Really important research which uses biological discoveries to respond to one of life's burning questions. Dr. Kenyon is super.

  • @worldofpaleoanthropology
    @worldofpaleoanthropology Рік тому

    Anything H.naledi, John Hawks, and Lee Berger, is a recipe for an amazing adventure.

    • @valoriel4464
      @valoriel4464 Рік тому

      Thx, always looking for more . Will ck them out.