DNA Replication

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  • Опубліковано 6 кві 2012
  • Paul Andersen explains how DNA replication ensures that each cell formed during the cell cycle has an exact copy of the DNA. He describes the Meselson-Stahl experiment and how it showed that DNA copies itself through a semi-conservative process. He then explains how multiple enzymes, like DNA polymerase, helicase, primase, ligase, and single strand binding proteins copy DNA. He also differentiates between the leading and the lagging strand. He explains how DNA is anti-parallel in nature and how eukaryotic cells have multiple origins of replication.
    Intro Music Atribution
    Title: I4dsong_loop_main.wav
    Artist: CosmicD
    Link to sound: www.freesound.org/people/Cosmi...
    Creative Commons Atribution License

КОМЕНТАРІ • 500

  • @josephcarnep4554
    @josephcarnep4554 8 років тому +694

    Who else can't learn during class so they watch these videos at home?? Very thankful for Mr. Anderson's videos.

    • @justinf6758
      @justinf6758 8 років тому +17

      My teacher is awful. Well known as a bad teacher in the school

    • @ticklesmcbufffletrutter210
      @ticklesmcbufffletrutter210 7 років тому +1

      What is their name? Mine is too

    • @Brcnosaur
      @Brcnosaur 5 років тому +10

      its not that my teacher is bad, how do you expect to learn the whole process in 1 2 hour class? thats the point of studying and shit

    • @Sagarikaze
      @Sagarikaze 4 роки тому +5

      my teacher goes sdakdsbdlasb and everybody in the glass be like yes, and shaking their head
      \

    • @ttylgirlzrock6
      @ttylgirlzrock6 4 роки тому +1

      Joseph Carnep 1 hour of learning and nothing is clicking this man spends 10 mins explaining and I learned everything

  • @nomuscleasianman
    @nomuscleasianman 10 років тому +390

    Two hour lecture in a 10 minute video

    • @BOSSxGLITCHES
      @BOSSxGLITCHES 7 років тому +10

      you know it man. thank you for supporting our country!

  • @AmazingTNT
    @AmazingTNT 8 років тому +364

    you have saved my ap bio test grades more than once

    • @bradclarke7874
      @bradclarke7874 8 років тому +1

      +P1tri0t If you can't keep up with the basics of DNA replication in class you may as well give up on any future in science-related education, lol

    • @AmazingTNT
      @AmazingTNT 8 років тому +65

      +Brad Clarke um no need to be a douche
      i hate dna, but anatomy, viruses, bacteria, and macromolecules interest me
      and whos to say i dont understand it, Bozeman is an excellent study resource and thats what im referring to

    • @person-wk2uf
      @person-wk2uf 8 років тому +22

      +Brad Clarke Lmao, your subscriptions don't exactly spell out " genius." Gtfo moron.

    • @rockthepunchx9547
      @rockthepunchx9547 7 років тому +14

      Or just spend a little more time in understanding how it works. Not everyone is as clever as you are, some may need to put in extra hours or gain different perspectives on how things work and bozeman science does put things in a clearer perspective. If you are so clever and only need the classes, why are you here anyway?

    • @jillian3047
      @jillian3047 7 років тому +9

      It's so cute how you just never responded to this, Brad! Really shows how much of a winner you are in life! :) Remind me again of your unfathomable brilliance?

  • @kevinsanchez1794
    @kevinsanchez1794 8 років тому +148

    Better than my teacher sir, keep up the work this is saving my grade and im so thankful that you were born

    • @TheCatMurgatroyd
      @TheCatMurgatroyd 8 років тому +47

      +Oh Sykezz
      you're so thankful that his DNA replicated...

    • @tannu8447
      @tannu8447 6 років тому +1

      hahhhahhah @the cat...

    • @Obibopbop
      @Obibopbop 3 роки тому

      @@TheCatMurgatroyd Lol

  • @ThabigT101
    @ThabigT101 9 років тому +64

    So i showed my biology teacher this video now when we were learning about cells and DNA, and he literally added it to his slideshows
    You are awesome mr Andersen!

  • @dragonsurge1
    @dragonsurge1 9 років тому +16

    Dude you are the science version of khan academy. Watching you vidios has made me feel much more confident about my upcoming science test.

  • @alexaparrales530
    @alexaparrales530 7 років тому +34

    God bless you Mr.Anderson, you are such a great teacher and you know how to really explain things well.

  • @shosha1771
    @shosha1771 7 років тому +35

    I've been getting A's because of you man. Not everyone can be a science teacher. Thank you

    • @antiiv11
      @antiiv11 7 років тому

      shadan hani glad I could help

  • @sanbehzad
    @sanbehzad 8 років тому +3

    I'm a Med 1 student, and i really enjoy the way you clarify every single thing in your videos. I think you have a great picture of nature and science in your mind. You go through all small details which it helps students to understand the basic of all meterials so clearly and get ready to move on to the advance levels. I have the utmost respect for you. I really appreciate it.

  • @sentientgarbages4435
    @sentientgarbages4435 3 роки тому +3

    I just wanted to stop by and say thank you for making these videos. I am a college student going into neurochemistry, and I am starting my intensive classes this fall. I'm going through all these videos to help refresh my memory and study before classes begin, and your videos have been the most helpful. Your pace, explanations, and even comparisons are easy to understand for me and entertaining at the same time. Thank you for helping my academic journey be less stressful!

  • @milenpatel
    @milenpatel 10 років тому +19

    I needed this video from basic biology and now I am in Advanced Molecular cell biology and still need it. Gotta love Mr. Anderson

  • @unfaithful1034
    @unfaithful1034 9 років тому +26

    Aish thanks lol
    All my science teacher seem to like stretching out their lessons and then I just get lost in the middle. You make it short and sweet. I actually get it now. I got more from this than the 2 periods of class I got. (My teacher is good, it's just I get bored once the teacher starts to talk about something else or make their analogy too long and then i just stop listening altogether)

    • @zaighamabbas2041
      @zaighamabbas2041 9 років тому +5

      same here............ i mean sometimes one is understanding perfectly but then the teacher(all respects and praises-not trying to be disrespectful) tells of a really messed up analogy and everything gets confusing

  • @bartholomewtheapostle8664
    @bartholomewtheapostle8664 8 років тому +141

    who else cramming for the ap bio exam tomorrow

    • @Cocohorse2648
      @Cocohorse2648 8 років тому

      me omg

    • @xxyeongi
      @xxyeongi 7 років тому +2

      History repeats :( my exam is tomorrow

    • @mgt7447
      @mgt7447 4 роки тому +2

      @Mathias Bendickson a 4 year timeline my test is this week corona edition im scared lol

    • @mrkrabs7321
      @mrkrabs7321 4 роки тому +3

      2 DAYS BOYS

    • @theboy6435
      @theboy6435 4 роки тому +2

      ahh shit

  • @djdeadhorses
    @djdeadhorses 4 роки тому

    your videos always help clear up anything i may have missed or didnt understand perfectly. whenever i need to study i look for your videos.

  • @janb.9046
    @janb.9046 2 роки тому +1

    My own instructor throws so much at us and in such a fragmented way. Thank you, Mr. Anderson!

  • @shayneallen7235
    @shayneallen7235 7 років тому

    I've been watching your videos for my bio classes and I just can not thank you enough. If you were my personal teacher, my future would be endless. Thank you, Mr. Anderson.

  • @camman1056
    @camman1056 9 років тому

    You're the best genetics teacher on here, I'm at a decent uni and even they just resort to waffling on and on without giving many solid explanations.

  • @IronIsSolace
    @IronIsSolace 11 років тому

    thank you so much for posting these Paul. this really helps those who are having trouble with bio because it feels more like a 1 on 1 teaching session, sort of like having a tutor, instead of a single teacher and a class of 40. keep up the good work!

  • @MissDelgado1
    @MissDelgado1 9 років тому +185

    The best science channel by far!!! You've helped me learn so much! Thank you! :)

    • @Bozemanscience1
      @Bozemanscience1  9 років тому +26

      ADRIANA KNIGHT Thanks so much. You are very kind.

    • @fmar105
      @fmar105 9 років тому +7

      ADRIANA KNIGHT Agreed. Whenever I get stuck on a concept, this channel always helps clear things up!

    • @GamingStates
      @GamingStates 9 років тому +8

      I watch this to study. Mr. Andersen makes it seem so... Understandable. Idk why

  • @thatonethingthatonetime6357

    Mr Anderson is an incredible individual, if you put the video on 2xs speed, he will talk almost as fast as my professor, couldn’t have gotten through classes without this guy.

  • @rithy8686
    @rithy8686 9 років тому +23

    Thank you for existing~

  • @amandasmith5251
    @amandasmith5251 10 років тому +1

    I'm a non-traditional med school candidate, and you are helping me sooooo much. When I'm a real doctor, I will make a HUGE donation to your efforts. Thanks for everything.

  • @deepthireddyvasi2075
    @deepthireddyvasi2075 9 років тому +5

    watched tons of videos but couldn't get rid of ambiguity regarding DNA REPLICATION.but eventually now i got it in my mind..its all because of this guy. truly that was an A1 podcast...kudos!!

  • @emmasanderson8543
    @emmasanderson8543 6 років тому

    Awesome video! You explain complex concepts in a non intimidating yet still informative way!!! Your teachings on biology chemistry and physics have helped me out alot through ny entire high school career thank you so much!

  • @istel3283
    @istel3283 10 років тому +8

    i have been watching you video nonstop cuz i have final exam in Genetics next week. Thank you

  • @emilie027
    @emilie027 11 років тому

    You are officially my hero! Thank so much for providing the clear-cut explanations I need with words that everybody that doesn't have a biology degree understands in just 10 minutes! I think you have helped countless desperate students, so please, keep it up :D!!

  • @artin9999
    @artin9999 8 років тому +1

    I watch your videos every day for my university biology course. Thank you so much. Your videos are amazing!

  • @Reiko29DBS
    @Reiko29DBS 2 роки тому

    glad you mentioned the backstory on the Okazaki's it's touching and I've been taking biology long enough that I'm shocked that I'm just now learning about it

  • @CandeseMichael
    @CandeseMichael 9 років тому +55

    I wish the replication was conservative so it could be easier to study. Ugh!

  • @mishab7709
    @mishab7709 10 років тому +4

    I'm a freshman in college and I have my final in Biology for majors in two days, and I have been watching your videos nonstop! They are so helpful! Thank you!

  • @louisegroton4722
    @louisegroton4722 7 років тому +1

    I like watching Crash course biology and then this because you go more in depth and I get a better idea of the subject. Thanks for helping me ace all my bio tests!

  • @sreytuoch
    @sreytuoch 10 років тому +2

    I'm taking microbiology this summer. Super fast track, only 8 weeks. We fly through chapters like it's nothing. This helps a lot.

  • @sarahperruzza5675
    @sarahperruzza5675 10 років тому

    Fantastic! I am in a university Cell Biology class and even though I have to go into a little more detail, you have done a better job explaining this process than my professor has all semester! Thank you very much, keep them coming!

  • @cassandcon
    @cassandcon 11 років тому

    So good man! Well done. Best tutorial video I have seen yet on transcription. 10/10

  • @averytilny9084
    @averytilny9084 10 років тому +13

    If I had discovered you at the beginning of the year, ap bio would have been sooo much easier.

  • @robertdlorm755
    @robertdlorm755 7 років тому

    Bless your soul for making these videos Mr. Bozeman

  • @xannaxberryx
    @xannaxberryx 12 років тому

    You make everything so easy to understand and follow!! I'm so grateful for your videos!

  • @paramsengar8716
    @paramsengar8716 5 років тому

    I have an exam on this tomorrow, bless your soul Mr. Andersen thank you so much

  • @liddlemissasian
    @liddlemissasian 9 років тому

    Your videos always save me! They're always so clear and direct! ^_^

  • @tomphillips3174
    @tomphillips3174 9 років тому

    Using your channel to help me get through my exams! So much help!

  • @SirEshtri
    @SirEshtri 9 років тому +39

    easier way to remember which end the stand is - "phosphates are phive ends"

    • @SirEshtri
      @SirEshtri 8 років тому +4

      ***** I have another one to remember all steps of mitosis correctly - I Peed My Adidas Trainers or if you are dirty like me, I Poked Michelle's Ass Thoroughly

    • @SirEshtri
      @SirEshtri 8 років тому

      ***** I just remebered trna is a bus aa is the passenger and the ribosome is the destination.

    • @SirEshtri
      @SirEshtri 8 років тому +1

      ***** sry, I only have mitosis, I memorized replication by searching for video on youtube and looking over the notes then reciting the replication process without help, I repeated this 2-3 times a day.

    • @biasuffi
      @biasuffi 8 років тому +21

      +Eshtri BEGIN = 5 letters, END = 3 letters

  • @B3bita1215
    @B3bita1215 11 років тому

    wow!! I had to learn this in a matter of minutes before my BIG test. Thank you soooo much Mr. Andersen you are a lifesaver :)

  • @mihaiionut2442
    @mihaiionut2442 10 років тому +4

    Thank you very much for your work. We appreciate your efforts.

  • @starflare93
    @starflare93 11 років тому

    Midterm tomorrow. I am a college student and this was just an excellent way to review everything for my test. SO. HELPFUL. THANK YOU.

  • @11muslim4life
    @11muslim4life 9 років тому

    YOU ARE SO GREAT!!! Literally started watching this in Honors Bio 2 years ago, and now I'm in AP Bio (with the same teacher btw) and these videos are still relevant to even advanced content!

  • @yashdeshpande2733
    @yashdeshpande2733 8 років тому +1

    Hats off to you, Mr. Anderson. You've got a ton of knowledge on all life sciences! And more of course.

  • @KendahlLandreth
    @KendahlLandreth 9 років тому

    You are so helpful and an amazing teacher! Thank you so much!

  • @mariahnicole5332
    @mariahnicole5332 2 роки тому

    Currently watching some of his videos and crocheting at the same times. His videos are so great

  • @sindoosawel4507
    @sindoosawel4507 10 років тому

    You just saved me from an hour of deciphering a chapter in my textbook. Thanks!

  • @tenjintsuyu3321
    @tenjintsuyu3321 6 років тому

    this was EXTREMELY helpful, thank you so much! i was so confused in class, but everything makes sense now :D

  • @linaandersson6112
    @linaandersson6112 2 роки тому

    Thank you so much! Your videos has totally SAVED me in uni chem and bio, you have such a simple way of explaining things that really works for my brain lol

  • @switfranc
    @switfranc 11 років тому +1

    clear diagram and a very well-made explanation makes biology much more interesting!

  • @kengilleo7885
    @kengilleo7885 10 років тому +1

    As a retired organic chemist, I've become fascinated with molecular biology and have time to learn. Thanks, this is great stuff.

    • @anshujoshi7842
      @anshujoshi7842 10 років тому

      One of my favourite topic in biology

  • @2116carlos
    @2116carlos 7 років тому +6

    thank you very much, you´re a very good teacher, im from colombia and i enjoy your videos and your pronunciation.

  • @Chenoah.
    @Chenoah. 3 роки тому +1

    I finally understand 3 and 5 prime. It only took years. Thank you!

  • @dannylabelle6933
    @dannylabelle6933 10 років тому

    Thank you so much.I finally understood DNA replication well. You are doing an amazing job putting up these videos.

  • @geoffreymccord372
    @geoffreymccord372 6 років тому

    Mr. Anderson, thank you so much for your videos! You are a God-send! I learn more from your videos than I do from my book.

  • @soccerchica303
    @soccerchica303 10 років тому

    People like you are the ones who are keeping those like me who have horrid biology teachers alive. Thank you.

  • @AB-uj6ej
    @AB-uj6ej 8 років тому

    Seriously ur videos always help so much thank u and keep up the good work

  • @MattyHawkHCF
    @MattyHawkHCF 11 років тому +1

    These videos are extraordinary. Thank you so much for what you do.

  • @ahmadidais5947
    @ahmadidais5947 8 років тому

    one of the best channels, thanks for all the help can you go through the 11 systems of the body briefly thanks

  • @miltonhuynh4209
    @miltonhuynh4209 3 роки тому +1

    I watched this video before a test in high school
    Then I came back to watch it before a midterm in college
    Now I'm back to review for a job interview tomorrow

  • @leverdo1166
    @leverdo1166 4 роки тому

    All your videos are great to learn in an easy and simple approach.A little correction for the picture at 4:59:
    In eukaryotic DNA polymerase, Pol ε (epsilon) is to extend the leading strand during replication, therefore Pol δ (delta) in the picture should be Pol ε (epsilon).
    Pol α (alpha) in the picture could be right polymerase on the lagging strand as Pol α starts replication elongating the primer with ~20 nucleotides.
    But, if it is more than 20 nucleotides, Pol δ (delta) primarily replicates the lagging strand, therefore Pol α (alpha) in the picture might be replaced by Pol δ (delta) as well

  • @cmatthews04
    @cmatthews04 11 років тому

    I'm really surprised you're just a "Mr.". You have the knowledge of a Biology genius that has AT LEAST as a doctorate.
    Thank you so much for helping me understand in 10 minutes what my college professors have tried to teach in a month!

  • @sandraloza-avalos7747
    @sandraloza-avalos7747 10 років тому

    better than my professors. thank you so much. I'm watching all of your videos to review for my exams.

  • @PortalRhyme
    @PortalRhyme 2 роки тому

    My guy posted a video 9 years ago, and he’s still helpin people today

  • @MHSMagicLuver
    @MHSMagicLuver 11 років тому +1

    amazing. missed the first lecture on this and have my second genetics midterm in college next wednesday.

  • @rachelo9oooyohannes254
    @rachelo9oooyohannes254 2 роки тому

    Thank you so much, have exam in few days and really need to understand it in depth and this was perfect example, Really appreciate it!

  • @Aditi_1319
    @Aditi_1319 3 роки тому +1

    this thing took tons of videos to learn but i still can't get it...and now after visiting here it's no brainer...thank you professor... :)

  • @miracleallums19
    @miracleallums19 8 років тому

    So easy to understand. Thank you! Great teaching qualities.

  • @BeautiFuFu
    @BeautiFuFu 12 років тому

    Your videos really help me. My bio professor doesn't lecture at all (which I don't get) he just does quizzes every class with iclickers. so im left to tech myself a whole coarse by reading a book. Reading doesn't really help me understand. Its like reading a book about how to solve algebra problems without really solving them, which is pointless. Your videos gives me the visuals/mini lectures I need to really understand.

  • @mrsmicaela13
    @mrsmicaela13 11 років тому

    I'm an Italian 16years-old student and I'm very pleased to say that YOU ARE BETTER THAN ALL ITALIAN BOOKS I've consulted, ALL ITALIAN TEACHERS I've heard talking about this PUT TOGETHER! THANK YOU

  • @Eztini
    @Eztini 11 років тому

    Greetings mate from a med student with an upcoming genetics exam who completely forgot what he learned in high school! Thanks!

  • @youngchase3636
    @youngchase3636 9 років тому

    very complicated, complex process, but thanks to you sir i can understand it a bit. Thank You very much!

  • @princepawka
    @princepawka 10 років тому +2

    Mr Anderson you have solved the puzzle, 5' to 3'.. Amazing Videos you have. Bless you.

  • @macxxfe
    @macxxfe 7 років тому +2

    Thank you very much. So clear explanation. And thanks for your clear pronunciation.
    Gracias. Saludos desde Argentina.

  • @jerseyboy22000
    @jerseyboy22000 11 років тому

    Nice job Mr. Anderson, Keep making the videos, they are a great help from a students point of view

  • @allextacy
    @allextacy 11 років тому

    you're completely saving my butt with these videos. thank you so much!!!

  • @jantines6840
    @jantines6840 7 років тому

    Thanks for your video's, they are very clear and helpful and they helped me a lot!

  • @doctorich
    @doctorich 10 років тому

    Many thanks...I'm looking at Bio 101 finals next week, and I was never really able to straighten out the basic machinations of replication. Now if I could only get a similar video about the functions of the different types of RNA.

  • @milenpatel
    @milenpatel 11 років тому +1

    OMG!!!! U LITERALLY SAID 3 WORDS AND I FINALLY UNDERSTOOD EVERYTHING! GO MR. ANDERSON!!!

  • @xEmoSunshine14x
    @xEmoSunshine14x 8 років тому +58

    If I close my eyes and listen, you sound a bit like Jim Halpert.

  • @sarahjuliamashburn5618
    @sarahjuliamashburn5618 10 років тому +1

    thank you so much for sharing this with us ! it's been beyond helpful

  • @Bruceskis83
    @Bruceskis83 11 років тому

    The visual for replication was incredibly helpful and made it easier to understand how helicase is melting the DNA so I can be copied.

  • @kyleeconseen2779
    @kyleeconseen2779 9 років тому

    Your video on dna helped me understand so much and know I'm watching this on for my science presentation and hopefully I go to state

  • @user-qo4fj1pe9p
    @user-qo4fj1pe9p 9 років тому

    Thank you for your kind explanation about DNA replication. I understand exactly because of you!

  • @barelyjesus1091
    @barelyjesus1091 8 років тому

    Best channel for learning it helped me study my biology lesson

  • @Angelicmey
    @Angelicmey 8 років тому

    your channel is very helpful, and this video helped me understand the concept. Thank you.

    • @meryemgokturk
      @meryemgokturk 8 років тому

      +‫مريام‬‎ :) my name is meryem tooo how awkward

    • @Angelicmey
      @Angelicmey 8 років тому

      No it's not awkward:) Hello to you:)

  • @kudashmudzamiri2430
    @kudashmudzamiri2430 8 років тому

    Mr Anderson......he just made the way to being my best biology teacher.

  • @sameerav1988
    @sameerav1988 8 років тому

    the best science learning videos i ever came across!!! thank u so much sir for ur support and effort for us.. :) one more new sub for ur channel! :)

  • @dageygalante1
    @dageygalante1 9 років тому

    Best lecture of DNA replication. Thank you very much

  • @holly8454
    @holly8454 4 роки тому

    watched all the ads on this video so you get paid for saving my life

  • @srikarchundru7596
    @srikarchundru7596 4 роки тому

    Thank You,
    Mr. Anderson

  • @DoctorStyle22
    @DoctorStyle22 12 років тому +1

    You saved my understanding for this

  • @caniko2
    @caniko2 8 років тому +2

    IMPORTANT FOR ADVANCED MOLECULAR BIOLOGY. The model figure of the DNA replication mechanism in eukaryotes is wrong:
    DNA polymerase alpha is supposed to be DNA polymerase delta; DNA primase is supposed to be DNA polymerase alpha; DNA polymerase delta is supposed to be DNA polymerase epsilon.
    You are welcome.

  • @Wasabillama
    @Wasabillama 11 років тому

    Mr.Anderson you always say, I hope it was helpful, your videos are always helpful. :)

  • @jaceylewis1267
    @jaceylewis1267 4 роки тому

    This is so much rich knowledge! Thank you sooooooooooooooooooooooooooo much for your help!

  • @minabilgin
    @minabilgin 11 років тому

    Wow this was pretty helpful and really amazing. Thank you for such a nice work like this :)

  • @mahips6045
    @mahips6045 10 років тому

    i was stuck with this dNA for the last 1 week ... thankyou sir ..( MR.Andersen .) " u r a proffesional "

  • @josh-rx6ly
    @josh-rx6ly 9 років тому

    dear sir thanks for the video. one small question in the part where you showed DNA being replaced (lagging end ) you said "so whats evoked is" how ever surely this system would have to of excised in the first cell in order to reproduce so how could it of evoked