I think I have severe trauma. When the word "coagulate" was mentioned, my mind changed it to "Coagulation Cascade". Oh the horrors! Is like hearing "Krebs Cycle" and "Electron Transport Chain" in a single phrase!
Hi Ahmed! Thanks for the feedback! Our videos at osmosis.org have assessment questions and high-yield notes that you may access anytime! Feel free to sign up for a free trial account if you haven't yet! 💕
I knew only a little of the wounds that occurred outside the body and didn't know the wounds or tissues inside the body, but thanks to this, I learned about various wounds and tissues outside and inside the body.
Just to add... Haemostasis itself is composed of five steps Vascular spasm Platelet plug formation Cascade (itself composed of many steps) Clot retraction and repair Fibrinolysis
I have seen or heard of some of the wounds on the human body, so I know some things, but I thought the knowledge I knew was very shallow. This is because I thought it was more diverse than I thought and taught me deeply about one thing. Also, I didn't know the treatment methods properly, but it was amazing to know.
Do analgesics like Tylenol and ibuprofen significantly interfere with the inflammatory stage and thus delay wound healing by 2ndary intent? Is one worse than the othe? Lastly, are there any significant difference in healing in the oral cavity, eg, tooth loss or extractions? Thank you.
Tylenol, or acetaminophen, is an anti pyretic primarily in additional to being an analgesic. Ibuprofen and most other nsaids are non steroidal anti-inflammatory and while also have analgesic properties, its primary function is to inhibit the inflammatory response aka swelling. Ibuprofen and nsaids work in the blood stream and prevent a certain stage of inflammation which prevents the process. This results in reduction in swelling which results in pain relief because the pain is from the increased pressure in the area from excess swelling. Acetaminophen or Tylenol doesnt do any of this; it works in the brain, the hypothalamus i believe, off the top of my head, and in the brain, it binds to receptors that cause the pain response and essentially tells the hypothalamus that everything is okay and they dont need to activate the cascade response like fever. Its analgesic properties occur secondary because the pain receptors are not being activated like they would normally. So with this understanding, Ibuprofen and Tylenol affect the process differently. Generally acetaminophen wont interfere with local inflammation like on a wound because the inflammation process is still occuring at that level. Ibuprofen however would potentially interfere with healing because the lack of inflammation prevents blood from transporting nutrients as quickly. However these are all considerations for treatment with a balance in mind. While we want a quick healing process of an injury, if the swelling is so extensive it cuts off circulation to the rest of the limb or prevents the injured area from being mobile then its warranted. If the swelling causes too much pain then the physiological response too the pain can divert energy and resources away from the injury. We have to remember that the body is not smart, just a machine and it will do something regardless of the affect on the larger system because it just reacts. As for your mouth question, different tissue has different needs for repair and saliva has alot of enzymes and nutrients that promotes healing in the mouth because it kills most forgein bodies and the protein amalyse can provide new protein structures for cell repair faster than other areas. In general to promote healing in most places, keep the area moist, protected from outside infections, and provide the body with rest of nutritional food. This will provide optimal chance for cell regeneration. I worked a pediatric clinic and many of my young patients had quick healing injuries because we cleaned them, covered them, and gave them rest and a chance to heal...and kids are good at following doctors instructions whereas adults often have differing opinions based on life experiences and anecdotal knowledge like the "let a wound breathe" concept. This can be good for a wound that has alot of discharge but most wounds are just being exposed to more bacteria and healing is delayed. The body is good at getting back to homeostasis, we just need to help it out.
Inflammatory is an important step but if this step is there for a longer time than usual than would healing slows as Transition from the inflammatory to the proliferative phase is a key step for faster recovery so to take anti-inflammatory drugs do not slows healing but we can say help to accelerate the step
My late husband had a good friend in Mobile, AL named “Chuck” Elsevier. The name “Elsevier” is so unusual, I am wondering if you are related to him. I would enjoy getting in touch with Chuck.
I think I have severe trauma. When the word "coagulate" was mentioned, my mind changed it to "Coagulation Cascade". Oh the horrors! Is like hearing "Krebs Cycle" and "Electron Transport Chain" in a single phrase!
You are mentioning all my fears in one comment that's not fair 😅
You can make these videos even more amazing if you add a quiz of 2 or 3 questions in the end for self assessment and that would make it perfect ✨✨
Hi Ahmed! Thanks for the feedback! Our videos at osmosis.org have assessment questions and high-yield notes that you may access anytime! Feel free to sign up for a free trial account if you haven't yet! 💕
Thanks for helping me understand my own wound better. I feel more at peace with what's happened because I now understand the process and type.
You're welcome! 💖
I knew only a little of the wounds that occurred outside the body and didn't know the wounds or tissues inside the body, but thanks to this, I learned about various wounds and tissues outside and inside the body.
The way you teach is just lovely.
Thank you! ❤️
Ive learned way more than i have learned in 2h long lectures.. bless you man❤️❤️
Happy to help! ✨
Just to add... Haemostasis itself is composed of five steps
Vascular spasm
Platelet plug formation
Cascade (itself composed of many steps)
Clot retraction and repair
Fibrinolysis
I have seen or heard of some of the wounds on the human body, so I know some things, but I thought the knowledge I knew was very shallow. This is because I thought it was more diverse than I thought and taught me deeply about one thing. Also, I didn't know the treatment methods properly, but it was amazing to know.
Is this process similar to muscle healing from a tear/strain? minus the epithelial and stem cells? Do you have a video for reference? Thank you
Thank you so much Osmosis! 🌸
I can never thank you enough for saving my precious time during final exams.
Peace & blessings !🕊🌸
Always our pleasure! 🥰
this video has made me like share and subscribe, Good work
Thank you! 💕
Do analgesics like Tylenol and ibuprofen significantly interfere with the inflammatory stage and thus delay wound healing by 2ndary intent? Is one worse than the othe? Lastly, are there any significant difference in healing in the oral cavity, eg, tooth loss or extractions? Thank you.
Tylenol, or acetaminophen, is an anti pyretic primarily in additional to being an analgesic. Ibuprofen and most other nsaids are non steroidal anti-inflammatory and while also have analgesic properties, its primary function is to inhibit the inflammatory response aka swelling. Ibuprofen and nsaids work in the blood stream and prevent a certain stage of inflammation which prevents the process. This results in reduction in swelling which results in pain relief because the pain is from the increased pressure in the area from excess swelling. Acetaminophen or Tylenol doesnt do any of this; it works in the brain, the hypothalamus i believe, off the top of my head, and in the brain, it binds to receptors that cause the pain response and essentially tells the hypothalamus that everything is okay and they dont need to activate the cascade response like fever. Its analgesic properties occur secondary because the pain receptors are not being activated like they would normally. So with this understanding, Ibuprofen and Tylenol affect the process differently. Generally acetaminophen wont interfere with local inflammation like on a wound because the inflammation process is still occuring at that level. Ibuprofen however would potentially interfere with healing because the lack of inflammation prevents blood from transporting nutrients as quickly. However these are all considerations for treatment with a balance in mind. While we want a quick healing process of an injury, if the swelling is so extensive it cuts off circulation to the rest of the limb or prevents the injured area from being mobile then its warranted. If the swelling causes too much pain then the physiological response too the pain can divert energy and resources away from the injury. We have to remember that the body is not smart, just a machine and it will do something regardless of the affect on the larger system because it just reacts. As for your mouth question, different tissue has different needs for repair and saliva has alot of enzymes and nutrients that promotes healing in the mouth because it kills most forgein bodies and the protein amalyse can provide new protein structures for cell repair faster than other areas. In general to promote healing in most places, keep the area moist, protected from outside infections, and provide the body with rest of nutritional food. This will provide optimal chance for cell regeneration. I worked a pediatric clinic and many of my young patients had quick healing injuries because we cleaned them, covered them, and gave them rest and a chance to heal...and kids are good at following doctors instructions whereas adults often have differing opinions based on life experiences and anecdotal knowledge like the "let a wound breathe" concept. This can be good for a wound that has alot of discharge but most wounds are just being exposed to more bacteria and healing is delayed. The body is good at getting back to homeostasis, we just need to help it out.
Inflammatory is an important step but if this step is there for a longer time than usual than would healing slows as Transition from the inflammatory to the proliferative phase is a key step for faster recovery so to take anti-inflammatory drugs do not slows healing but we can say help to accelerate the step
My late husband had a good friend in Mobile, AL named “Chuck” Elsevier. The name “Elsevier” is so unusual, I am wondering if you are related to him. I would enjoy getting in touch with Chuck.
good job
it is a good explanation
Thank you! 💕
6:24 took me out😭
Love it
❤
☂️🍎🍉🍌🍏🍓
🍇🍋🍐🍍