Ageing, Senescence and the Kidney | Dr David Ferenbach

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  • Опубліковано 2 лис 2024

КОМЕНТАРІ • 11

  • @eugeniebreida1583
    @eugeniebreida1583 2 роки тому +1

    My word, such an engrossing presentation, and presentation style, Dr. Fedenbach!
    I can hardly imagine this material coming more alive to a layperson - not to mention to other scientists at your level of discovery. Brilliant.
    Thank you for your obvious effort in bringing this material together.

  • @rustybolts8953
    @rustybolts8953 2 роки тому

    Just discovered NUS Young Loo Lin videos. Will be watching every single one. They are so very informative and technically detailed. Yet clear and understandable. Leaving little to Google or Duck.

  • @abdelilahbenahmed4350
    @abdelilahbenahmed4350 2 роки тому +1

    Thx for all these valuable infos. Could autophagy through eliminating senescent cells help in improving renal function ? If so what would be the most effective intermittent fasting regimen ?

    • @nattydred2593
      @nattydred2593 2 роки тому +1

      I'm curious about this too. Knowing something like this would provide a very welcome link between this research and something actionable. Actually any information about lifestyle factors that contribute to kidney injury or health.

    • @nattydred2593
      @nattydred2593 2 роки тому +2

      I've just viewed Prof Luigi Fontana's presentation from Sept 15, and he cites data that suggests that:
      - intermittent fasting appears to be clearing senescent cells according to some bio markers
      - intermittent fasting appears to be improving kidney function (as measured by markers such as serum albumin)

    • @abdelilahbenahmed4350
      @abdelilahbenahmed4350 2 роки тому

      @@nattydred2593 Great. Thank you very much.

    • @eugeniebreida1583
      @eugeniebreida1583 2 роки тому

      Well, this is a lab w/specific research underway. I might think a primary benefit to kidney health we control might be regular hydration - w/proper electrolyte balance, and preventing excessive protein breakdown (muscle wasting?)
      Mine are guesses, but just to say an entirely different ball of wax to subject of presentation.
      Dr Google might be your man when it comes to clinical/diet/health related “maintaining optimal kidney function”

    • @eugeniebreida1583
      @eugeniebreida1583 2 роки тому

      Why am I under the impression Senescent cells do not autophage?

  • @rhyothemisprinceps1617
    @rhyothemisprinceps1617 2 роки тому

    It's been a few days since I watched - IIRC there was something about sex differences & also something about hypoxia. PON2 activity is higher in the female brain & this relates to increased hypoxia tolerance. I think PON2 is also expressed in kidneys.