I remember histidine as an upside down house (H for house) : turn you paper upside down, draw a basic house shape (5 lines). The house smoke at the top right corner (N) coming out of a chimney that runs down the right hand side of the house (the double bond). There is a path leading up to the bottom left corner side (NH), and a solar panel on the left side of the roof (another double bond). If you turn you paper the right way up you can draw the alanine backbone and join them up with an extra line. Thanks, great video!
it's really funny you mentioned this technique because if you go to the Sistine chapel today, there's a gentleman yelling "SH. NO PHOTO. SH." at all times. Kind of takes away from the experience, but I'll never forget Cysteine now.
This video is so helpful with remembering structures! I"m not sure if this is helpful, but for the MCAT I know you have to be quick to recognize if an AA is polar/nonpolar/acidic/basic,etc. which may not allow the time to write out each AA structure. So here's some silly mnemonics.. imagine these coming from a tween girl. 'HAL' basic of you! (Histidine,Arginine,Lysine) Ugh, don't be phobic, try on this FLAV WIG (FLAVWIG goes with the 1 letter abbreviation of the 7 non polar/hydrophobic AAs) Polar is Not QTSY (N for Asparagine, Q for Glutamine(Qutamine), Threonine, Serine, Tyrosine (Y)) Wow, he's so MCSulfur (like Mc.dreamy....idk. but MC is for Methionine and Cysteine for sulfur containing AAs) These are silly but I can't forget the properties of AA R groups now, and I also get an occasional laugh while MCAT studying (which is at times hard to do) Best of luck!
Thank you! And just in case for others, be careful that in 'HAL' basic of you, the A stands for Arginine in this case but that is NOT the single letter abbreviation for Arginine. Just be aware.
to remember the pka of aspartate and glutamate, D (Asp) abbreviation is the fourth letter of the alphabet. E(Glu) abbreviation is 1 letter after D. So therefore the pka is 4.1
Your comment was the first one i saw and i was like “pshh i doubt the comment section is THAT helpful”.... welp i was wrong. People have great ideas in the comments
+Jordan Olsen It is a very nice video, but I don't see the point in remembering all of these Amino acids. This is a topic you look up if it's needed, just like the cellular respiration.
+Marvin Me lol i wish, these are a must know for me in my major... thought i could short term them and look them up later but they have been on every exam so far. not only am i expected to know these like the back of my hand, but im suppose to know which ones are acidic and basic and many other properties of each. This video helped me pass my first exam but i keep having to come back to make sure i still have them.
+AnyiRhema || +Jacob Hoffman Really? Are you studying pharmacy/Biochemistry? If so, there is no doubt you will need them. I fight with other things (metabolism, Physiology, Anatomy) in medicine. This is one out of a lot topics, that's why I assume it is not as important as Anatomy/Physiology for example.
The way I remember the pKa of Asp and Glu is from their 1 letter abbreviation. D is the 4th letter of the alphabet and E is 1 letter further. Therefore, we have 4.1. Great video! So helpful!
Here are the ways I remember the abbreviations for Glutamine: First, I remember that it's Gln, not Glu, because Glutamine has the -amine ending which has an N in it. Then, I make the connection between Gln and Q with the name Glenn Quagmire from Family Guy (GLeNn Quagmire). I hope this helps some people. :)
Not sure if someone else mentioned this, but a way to remember the pka of aspartic acid and glutamic acid would be to recall the single-letter abbreviation of aspartate, which is D. D is the 4th letter of the alphabet, so pka ~ 4 and since the single-letter abbreviation of glutamate is E, you spell 'glue" which has 4 letters. Might be a stretch, but it seems to work for me. Thanks a bunch for all the helpful tips!
OMG.. THANK YOU !!!!!!! I've been trying to remember those amino acids for months !! Took me and hour (learning the method and doing some quick tests over the internet) to learn it BY HEART. I'm so grateful you have no idea.
WOW, just wow. Thank you so much for creating this! It is super helpful and I learned this over the course of 3 hours with breaks. Like everyone who's a mnemonic person and visual learner should look at this! Thanks for taking the time to make this and simplify so much!
For Arginine I know that its abbreviation is "R" and it takes 3 pen strokes to write "R" so 3 carbon chain and then 3 Nitrogens surrounding the fourth and last carbon. Helped me and I hope it helps someone else.
Histidine, His for house! I see the ring attached on it as a pentagon, and it looks like a little house with nitrogens on the roof if you draw it the right way :)
THIS IS THE BEST!!! AHHHH THIS HELPED ME SO MUCH!!!!!! YOU GUYS ARE LIFE SAVERS:) I really appreciate it! Now I can go into my biochemistry exam super confident. No joke, this was super helpful! Again, thank you!
Pka for Aspartate and Glutamate = 4.1 that means D is the letter which comes 4th in the series(of course alphabet). So D=4 and E comes next so variation would be 1 so 4.1. Cheers
I have been avoiding memorizing these for too long, this is the best video ever! Finally learned the amino acids even though they've been taught to me conventionally a couple of times. THANK YOU keep up the amazing work!
ooooooh MY GOD!!! i was freaking out for an exam that i needed to memorize all this. night before my exam i found it and helped soooooooo much!!! thank you for taking the time to make this video for people that can memorize stuff easily. thank youuuu!!!
This is the best way to learn things ever! i wish your channel did more than medical applications. Does anyone know a channel that does this kind of memory assistance for other subjects?
This video is brilliant. It has potentially saved me hours of penciling around on a notepad trying to remember each amino acid individually. :P Thank you so much! :D
you know what...i just appreciate the way this mans mind works!! its mind blowing...the fact that he can find the links to certain stuff..like whoah! real genius.
I love this! Thank you so much!! You should put a link in the description for Part 1 of this video and vice versa (put a link to Part 2 in the description for Part 1) so we can easily go from Part 1 to Part 2. Seriously saving my butt in Pharmacy school!!!
For Glutamine. To remember the letter Q. Think of the muscle group Glutes (Butt) and how they're right next to your Quads (Thighs). GLUT(E)amine - Gln - Q(UAD)
pka for the side chain in the his =6,,you have a pka for the amino group and the carboyl group in his too..and that's true for all amino acids,thank you for making it easy to memorize
This was amazing. Thank you. I have such a hard time learning structures,and you made this really easy. I watched each of the videos twice, and I have it down pretty well. I have an exam covering this material in the morning. Just wanted to say thanks!
For lysine, the letter K reminds me of Potassium since bananas have potassium, I use the Gwen Stefani Song, "Hollaback Girl" to count my carbons starting with drawing the bond from the alpha carbon to the beta carbon. That is your "B" then gamma carbon is "A" then delta carbon is "N" then epsilon carbon is "A" then your amine group is the "N." when you're stressed from studying these amino acids you can just remember "that the s*** is bananas" with lysine. Also, for tryptophan, remember that it's the only one with an indole group and use the three letter name "Trp" as in, "Don't mistakenly Trp on tryptophan."
Asp-D. D is the 4th letter of the alphabet, which you can relate to the pKa of 4.1. Just to use the same trick you did with Lysine. Thanks for the videos, no better way to carry science around than with mnemonics.
Its hard to explain w/o drawing but for Histidine, since its letter is H, draw an H (above the alanine backbone), but imagine that the bottom left line of the H swings up to make a double line (bond) with the horizontal line of the H. so now it basically looks like a four and the horizontal line of the four is a double bond. then just put your N and NH at the top of each line of the H and connect them with a carbon above to complete the five membered ring. It helps to tilt the H to the right.
Histidine R group has a lowercase b shape. The connection can be made because people need Benadryl for allergies (histidine forms histamine through decarboxylation). It's a stretch, but I think it will help me and maybe it will help others.
Glutamine: Glutamine is a "cute" (Q-te) amine :) Cysteine: Hissing sound at the beginnine "SSSSSysteine" --> add a sulfur to backbone Lysine: "Lysine is a Liar, but it's oK" (to remember that the symbol is K and not L); also, the letter K has four points, so there should be four carbons (including the carbon in the backbone) and the last carbon is connected to a positively charged amino group (its positive to offset the negative fact that lysine is a liar lol) hope these helped!
@odearjenzhere: Thank you! We appreciate your appreciation! Spread the word, we will take requests and ideas (we won't 'take' them, we'll help share them). Thank you!
Nice! for Asp (D) and Glu (E), the pka ~ 4, D is the fourth letter, since ASP is closer to the carboxyl group it won the letter challenge....someone probably already said that but it came to mind. Thank you so much! I have been struggling in biochem lecture to understand (hard since there never seems to be a straight line from here to there!)
Abbreviation for aspartate is D. D is the fourth letter of the alphabet... pKa≈4. (Apologies if that's been mentioned before... I'm sure it has.) Also instead of saying a comes before g for aspartate, you could have also said D Comes before E. Thanks BTW, this was super helpful!
Some weird phrases and tricks that are just quirky enough to stick in the memory bank, great video! I am in biochem and I will definitely be passing this onto my peers.
The pKa for these two acids that I have is 4.4. "4" looks a little like "A", and both of these acids are 'A'cidic. Then there are two of these 'A'cidic side chains so you have 'AA' ===> 4.4
Phenomenal, I like to make it a bit simpler for remembering. SCAFY-- Alanine at the middle, on the left I add SH to get Cysteine and OH to get Serine. and on the right, i add a phenyl group to get Phenylalanine and then and OH on top of F to get Tyrosine. TV-- Threonine is just a replacement of one of Valine's methyl group with and OH group
for the pka of aspartic acid and glutamic acid, you can think of it as how the A in Asp looks like a 4 with another line sticking out of the left side of it :)
Another way I usually differentiate between the Glu's and Asp's is that, they go hand in hand, almost similar structures, however, when I think of Glu, I think of GLUTTEN, since a glutten overeats, the Glu's have one more C than Asp's :)
Thanks so much. Helps me alot. for the Asparatic acid ( D ) and Glutamic acid ( E ), Pka = 4.1 we can remember it as : letter D is the number [ 4 ] of the alphabet then [ .1 ] is that letter E comes after D :)
This stuff is so cool. I really want to take organic chem. just for fun. Thanks for the upload, I like the way these are paired with the almost visual-mnemonic sort of aspect.
for the pKa = 4.1 for glutamate the number "4" looks like an upside down "g" for glutamate if you rotate the 4 90 degrees counterclockwise ( a bit of a stretch but it may help)
Here's a helpful hint for remembering the structures for Asparagine/N and Glutamine/Q. Both of the carboxyamide groups. However, the carboxyamide group in "A"sparagine is DIRECTLY attached to the (beta carbon of the) "A"lanine backbone, whereas the carboxyamide group in "G"lutamine is attached to the "G"amma carbon (implying an extra carbon).
Lysine - looks like L 😜 maybe it will help somebody ( L indstead of "k without vertical line ) 2:13 Also Histidine - imidazol group (both have 2 i- letters) By the way- super video! Helped so much 🙂
The easiest way to distinguish between Asp/Glu and Asn/Gln is that you have 1 ass but 2 glutes. Thus there is 1 carbon in between the functional group and the amino acid backbone (1 beta carbon) for Asp and Asn. And since we sit on 2 glutes there are 2 carbons in between the functional group and the backbone (beta and gamma carbon). So all you have to remember is that you have one ass, which contains 2 glutes ;)
The 3 amino acids with a Phenyl group: "Trip To Paris" or Tryp To Paris", TRYPtophan, TyrOsine, Phenylalanine. And continuing with the trip idea, the tryp (trip) was made an a Tyre (tire) shaped like an OH, "Y"?----Y to get to Paris, France, of course! P, F (Phenylalanine is shortened to F, not P.)
Glue E and Asp D both have 4 letters and are the only ones with PKA's around 4!! Or they end in mate and tate and that's 4 letters which is close to PKA of 4.
How I remember Aspartic Acid having a D as its one letter abbreviation is thinking of Aspartic acid as AsparDic acid. And For lysine, I think of LyKsine so its one letter abbreviation would be K for lysine. Hope that helps.
I remember the PKa of Asp/Glu like this: D is the 4th letter of the alphabet, = 4 E is the 5th letter; ONE higher than D = 1 Ergo, 4.1 :) Ty for the vids
I remember histidine as an upside down house (H for house) :
turn you paper upside down, draw a basic house shape (5 lines). The house smoke at the top right corner (N) coming out of a chimney that runs down the right hand side of the house (the double bond). There is a path leading up to the bottom left corner side (NH), and a solar panel on the left side of the roof (another double bond). If you turn you paper the right way up you can draw the alanine backbone and join them up with an extra line. Thanks, great video!
For cystine, I think of the sistine chapel. SH! No talking during the sermon!
it's really funny you mentioned this technique because if you go to the Sistine chapel today, there's a gentleman yelling "SH. NO PHOTO. SH." at all times. Kind of takes away from the experience, but I'll never forget Cysteine now.
And I think Sistine is Pristine to remember that Cystine is Polar. hehe.
Same!!
This video is so helpful with remembering structures!
I"m not sure if this is helpful, but for the MCAT I know you have to be quick to recognize if an AA is polar/nonpolar/acidic/basic,etc. which may not allow the time to write out each AA structure.
So here's some silly mnemonics.. imagine these coming from a tween girl.
'HAL' basic of you! (Histidine,Arginine,Lysine)
Ugh, don't be phobic, try on this FLAV WIG (FLAVWIG goes with the 1 letter abbreviation of the 7 non polar/hydrophobic AAs)
Polar is Not QTSY (N for Asparagine, Q for Glutamine(Qutamine), Threonine, Serine, Tyrosine (Y))
Wow, he's so MCSulfur (like Mc.dreamy....idk. but MC is for Methionine and Cysteine for sulfur containing AAs)
These are silly but I can't forget the properties of AA R groups now, and I also get an occasional laugh while MCAT studying (which is at times hard to do)
Best of luck!
Oh my god! You just saved me from losing some points on the MCAT! thanksss
You're a freaking genius and I love you. Thank you so much.
Thank you! And just in case for others, be careful that in 'HAL' basic of you, the A stands for Arginine in this case but that is NOT the single letter abbreviation for Arginine. Just be aware.
same for L, stands for Lysine (K) NOT leucine
or basic HomewRecKer
List of contents:
Asparagine 0:20
Glutamine 0:20
Cystein 1:50
Lysine 2:13
Arginine 3:25
Histidine 4:25
Aspartic acid 5:28
Glutamic acid 5:28
For glutamine, think "I need to look CUTE (Q), so I have to work on my glutes." Glutamine= "Qutamine".
That is so silly that I will never forget it. Thank you.
+The Billa I was thinking the same thing!
+arielartista Thank you stranger! That helped me :)
Good shit
to remember the pka of aspartate and glutamate, D (Asp) abbreviation is the fourth letter of the alphabet. E(Glu) abbreviation is 1 letter after D. So therefore the pka is 4.1
Vidoe is very well put together, helped me a lot. Also surprisingly helpful comment section. Good job everyone!
Your comment was the first one i saw and i was like “pshh i doubt the comment section is THAT helpful”.... welp i was wrong. People have great ideas in the comments
I think of of Tyrosine as TIRE - OH seen. When he draws it in this video it looks like a tire (the benzene ring) with an OH on top.
those 18 dislikes are the 18 who failed there first amino acid test
+Jordan Olsen that comment was the first misuse of "there" and "their"
+Jordan Olsen It is a very nice video, but I don't see the point in remembering all of these Amino acids. This is a topic you look up if it's needed, just like the cellular respiration.
+Marvin Me lol i wish, these are a must know for me in my major... thought i could short term them and look them up later but they have been on every exam so far. not only am i expected to know these like the back of my hand, but im suppose to know which ones are acidic and basic and many other properties of each. This video helped me pass my first exam but i keep having to come back to make sure i still have them.
+Marvin Me sometimes you really need to, at least in the exam
+AnyiRhema || +Jacob Hoffman Really? Are you studying pharmacy/Biochemistry? If so, there is no doubt you will need them.
I fight with other things (metabolism, Physiology, Anatomy) in medicine. This is one out of a lot topics, that's why I assume it is not as important as Anatomy/Physiology for example.
The way I remember the pKa of Asp and Glu is from their 1 letter abbreviation. D is the 4th letter of the alphabet and E is 1 letter further. Therefore, we have 4.1. Great video! So helpful!
Here are the ways I remember the abbreviations for Glutamine: First, I remember that it's Gln, not Glu, because Glutamine has the -amine ending which has an N in it. Then, I make the connection between Gln and Q with the name Glenn Quagmire from Family Guy (GLeNn Quagmire). I hope this helps some people. :)
Not sure if someone else mentioned this, but a way to remember the pka of aspartic acid and glutamic acid would be to recall the single-letter abbreviation of aspartate, which is D. D is the 4th letter of the alphabet, so pka ~ 4 and since the single-letter abbreviation of glutamate is E, you spell 'glue" which has 4 letters. Might be a stretch, but it seems to work for me. Thanks a bunch for all the helpful tips!
OMG.. THANK YOU !!!!!!! I've been trying to remember those amino acids for months !! Took me and hour (learning the method and doing some quick tests over the internet) to learn it BY HEART. I'm so grateful you have no idea.
mala maya
for Asp (D) D is the 4th letter of the alphabet -- 4 carbons
for Glu (E) E is the 4th letter of the alphabet -- 5 carbons
WOW, just wow. Thank you so much for creating this! It is super helpful and I learned this over the course of 3 hours with breaks. Like everyone who's a mnemonic person and visual learner should look at this! Thanks for taking the time to make this and simplify so much!
For Arginine I know that its abbreviation is "R" and it takes 3 pen strokes to write "R" so 3 carbon chain and then 3 Nitrogens surrounding the fourth and last carbon. Helped me and I hope it helps someone else.
helped me
Good one
Good
Histidine, His for house! I see the ring attached on it as a pentagon, and it looks like a little house with nitrogens on the roof if you draw it the right way :)
THIS IS THE BEST!!! AHHHH THIS HELPED ME SO MUCH!!!!!! YOU GUYS ARE LIFE SAVERS:) I really appreciate it! Now I can go into my biochemistry exam super confident. No joke, this was super helpful! Again, thank you!
for aspartic acid, I pronounce it AsparDic Acid, to remember that the one-letter abbreviation is D.
giggity
I LOVE THIIIISSS!!
the guy saying this seems so shy and sweet and i have a serious crush on this person i've never seen
HA.......gayyyyyyyyyyyyyyyyyyyy
Pka for Aspartate and Glutamate = 4.1 that means D is the letter which comes 4th in the series(of course alphabet). So D=4 and E comes next so variation would be 1 so 4.1.
Cheers
I have been avoiding memorizing these for too long, this is the best video ever! Finally learned the amino acids even though they've been taught to me conventionally a couple of times. THANK YOU keep up the amazing work!
ooooooh MY GOD!!! i was freaking out for an exam that i needed to memorize all this. night before my exam i found it and helped soooooooo much!!! thank you for taking the time to make this video for people that can memorize stuff easily. thank youuuu!!!
These 2 videos saved my butt a couple months ago for my biochemistry test, now i'm reviewing for the final and I still remember them! Thank you!
Do you go to UTSA by any chance? If so - I'm right there with you!
i memorized them in 30 min
and mastered them in 70min
THANK YOU
This is the best way to learn things ever! i wish your channel did more than medical applications. Does anyone know a channel that does this kind of memory assistance for other subjects?
You guys rock! Watched both videos and had all 20 memorized in less than an hour!
This is by far the BEST and most useful video for memorizing the AAs
Another way to remember that Asp is D --> *Asp*artic aci*D* (first and last letters)
This video saved my butt for my biochem quiz. Thank you!!
This video is brilliant. It has potentially saved me hours of penciling around on a notepad trying to remember each amino acid individually. :P Thank you so much! :D
sean & co. you guys are insanely awesome. thank you + much appreciation!
Guys, if I pass my exam it's gonna be all on you and your 2 videos!!!! Thank you soooo much for this! I really appreciate it! Helped me immensely!
you know what...i just appreciate the way this mans mind works!! its mind blowing...the fact that he can find the links to certain stuff..like whoah! real genius.
I love this! Thank you so much!! You should put a link in the description for Part 1 of this video and vice versa (put a link to Part 2 in the description for Part 1) so we can easily go from Part 1 to Part 2. Seriously saving my butt in Pharmacy school!!!
It's really helpful!! I memorized 5 AA each day, and now i won't forget them anymore:))
18 people dislike science! This really helped! Also for W tryptophan say it like Elmer Fudd. TrWyptophan. Stress the W.
For Glutamine. To remember the letter Q. Think of the muscle group Glutes (Butt) and how they're right next to your Quads (Thighs). GLUT(E)amine - Gln - Q(UAD)
I love you guys so much. I'm a visual person by nature because I'm an artist so this really, really helped me!!
this is the most useful video I have EVER seen on youtube. Thank you so much.
pka for the side chain in the his =6,,you have a pka for the amino group and the carboyl group in his too..and that's true for all amino acids,thank you for making it easy to memorize
This was amazing. Thank you. I have such a hard time learning structures,and you made this really easy. I watched each of the videos twice, and I have it down pretty well. I have an exam covering this material in the morning. Just wanted to say thanks!
this video is a serious life saver!!! helped me learn all of them in an hour!
Thank you so much for the videos, they are very helpful. GLU E and ASP D are four letters each and both have carboxylate groups (pka=4)
Just love it!!!! literally in 20 mins I understand everything! Thank You!
For lysine, the letter K reminds me of Potassium since bananas have potassium, I use the Gwen Stefani Song, "Hollaback Girl" to count my carbons starting with drawing the bond from the alpha carbon to the beta carbon. That is your "B" then gamma carbon is "A" then delta carbon is "N" then epsilon carbon is "A" then your amine group is the "N." when you're stressed from studying these amino acids you can just remember "that the s*** is bananas" with lysine. Also, for tryptophan, remember that it's the only one with an indole group and use the three letter name "Trp" as in, "Don't mistakenly Trp on tryptophan."
Asp-D. D is the 4th letter of the alphabet, which you can relate to the pKa of 4.1. Just to use the same trick you did with Lysine. Thanks for the videos, no better way to carry science around than with mnemonics.
Its hard to explain w/o drawing but for Histidine, since its letter is H, draw an H (above the alanine backbone), but imagine that the bottom left line of the H swings up to make a double line (bond) with the horizontal line of the H. so now it basically looks like a four and the horizontal line of the four is a double bond. then just put your N and NH at the top of each line of the H and connect them with a carbon above to complete the five membered ring. It helps to tilt the H to the right.
Histidine R group has a lowercase b shape. The connection can be made because people need Benadryl for allergies (histidine forms histamine through decarboxylation). It's a stretch, but I think it will help me and maybe it will help others.
Thanks for the time and effort to make this video, it helped a lot!
Glutamine: Glutamine is a "cute" (Q-te) amine :)
Cysteine: Hissing sound at the beginnine "SSSSSysteine" --> add a sulfur to backbone
Lysine: "Lysine is a Liar, but it's oK" (to remember that the symbol is K and not L); also, the letter K has four points, so there should be four carbons (including the carbon in the backbone) and the last carbon is connected to a positively charged amino group (its positive to offset the negative fact that lysine is a liar lol)
hope these helped!
Arginine = Argi-Nine = 4+9 =13 for the pKa.
thank you so much to whoever made this. Life savers!!
@odearjenzhere: Thank you! We appreciate your appreciation! Spread the word, we will take requests and ideas (we won't 'take' them, we'll help share them).
Thank you!
Nice! for Asp (D) and Glu (E), the pka ~ 4, D is the fourth letter, since ASP is closer to the carboxyl group it won the letter challenge....someone probably already said that but it came to mind. Thank you so much! I have been struggling in biochem lecture to understand (hard since there never seems to be a straight line from here to there!)
I'll re-comment when I finish reviewing the video for a second time. But thank you so much!
Abbreviation for aspartate is D. D is the fourth letter of the alphabet... pKa≈4. (Apologies if that's been mentioned before... I'm sure it has.)
Also instead of saying a comes before g for aspartate, you could have also said D Comes before E.
Thanks BTW, this was super helpful!
Some weird phrases and tricks that are just quirky enough to stick in the memory bank, great video! I am in biochem and I will definitely be passing this onto my peers.
One of the best vids to help memorize the aa's. Thanks guys!!!
for Glutamine, and easy way to remember that its single letter is Q is this, "Those Glutes are Cute" "Cute->cue->Q"
Gonna have a quiz about these 20 craps tomorrow. Thanks a lot for both of the vids! :)
Trick with Asp-D and Glu-E
The pKA is between 4 and 5. D is the 4th letter of the alph, and E is the 5th letter :)
Such a helpful video! Thank you so much! I was able to learn all of these really quickly! Great video! Couldn't give enough thumbs up!!! 👍
The pKa for these two acids that I have is 4.4.
"4" looks a little like "A", and both of these acids are 'A'cidic. Then there are two of these 'A'cidic side chains so you have 'AA' ===> 4.4
For pKa (4.1) of glutamate and aspartate, they're in one (1) group of 4 (glutamate, aspartate, glutamic acid, aspartic acid) --> 4 in 1 --> 4.1
Phenomenal, I like to make it a bit simpler for remembering.
SCAFY-- Alanine at the middle, on the left I add SH to get Cysteine and OH to get Serine. and on the right, i add a phenyl group to get Phenylalanine and then and OH on top of F to get Tyrosine.
TV-- Threonine is just a replacement of one of Valine's methyl group with and OH group
helped me :) thank you 😃
Many thanks from a Swedish med student in Hungary.
For Histidine I remember it by saying:
"Make a Home Plate with N's."
That way I know it's a 5 member ring, and that there are 2 N's in there.
This is INCREDIBLE. Thank you so much for putting it together!
On Cysteine its 3 letter is Cys the "s" is what helps me remember to add a SH to an Alanine, since Alanine is the "backbone".
Thanks much ... great method for learning as i have biochem 1 exam on wednesday. btw what program and input method was used to do this?
for the pka of aspartic acid and glutamic acid, you can think of it as how the A in Asp looks like a 4 with another line sticking out of the left side of it :)
Another way I usually differentiate between the Glu's and Asp's is that, they go hand in hand, almost similar structures, however, when I think of Glu, I think of GLUTTEN, since a glutten overeats, the Glu's have one more C than Asp's :)
Brandford Adobaw I always think you eat asparagus, then it turns into glucose
Thanks so much. Helps me alot. for the Asparatic acid ( D ) and Glutamic acid ( E ), Pka = 4.1 we can remember it as : letter D is the number [ 4 ] of the alphabet then [ .1 ] is that letter E comes after D :)
Hope you realize that this is mnemonic mastery. Excellent compression of information :). Thx a lot!
This stuff is so cool. I really want to take organic chem. just for fun. Thanks for the upload, I like the way these are paired with the almost visual-mnemonic sort of aspect.
This has made life a hell of a lot easier. Thnx guys ! ! ! :)
for the pKa = 4.1 for glutamate the number "4" looks like an upside down "g" for glutamate if you rotate the 4 90 degrees counterclockwise ( a bit of a stretch but it may help)
Here's a helpful hint for remembering the structures for Asparagine/N and Glutamine/Q.
Both of the carboxyamide groups. However, the carboxyamide group in "A"sparagine is DIRECTLY attached to the (beta carbon of the) "A"lanine backbone, whereas the carboxyamide group in "G"lutamine is attached to the "G"amma carbon (implying an extra carbon).
for aspartate and glutamate you can use the pKa of ~4 to remember that these are the two with the secret 4 letter codes - GluE and AspD
You could even go further than that.
D is the fourth letter of the alphabet, E is the next letter after D (D+1 = E). Ergo:
D= 4 , E= D+1 -> 4,1
Lysine - looks like L 😜 maybe it will help somebody ( L indstead of "k without vertical line ) 2:13
Also Histidine - imidazol group (both have 2 i- letters)
By the way- super video! Helped so much 🙂
The easiest way to distinguish between Asp/Glu and Asn/Gln is that you have 1 ass but 2 glutes. Thus there is 1 carbon in between the functional group and the amino acid backbone (1 beta carbon) for Asp and Asn. And since we sit on 2 glutes there are 2 carbons in between the functional group and the backbone (beta and gamma carbon). So all you have to remember is that you have one ass, which contains 2 glutes ;)
aspartic ACID, glutamic ACID (4 letters, pka= 4)
Great! Tyrosine .... is Y-ro so that gives you your abbreviation and roh gives you the R-OH group (phenol)
The 3 amino acids with a Phenyl group: "Trip To Paris" or Tryp To Paris", TRYPtophan, TyrOsine, Phenylalanine.
And continuing with the trip idea, the tryp (trip) was made an a Tyre (tire) shaped like an OH, "Y"?----Y to get to Paris, France, of course! P, F (Phenylalanine is shortened to F, not P.)
Thank you for the effort to produce this video.
thank you ..i have an exame tomorrow so this is very helpful to memorize
Comments are half my notes! video super helpful and all the responses too!
A is the first letter and G is the 7th letter. If you add them up and divide by two, you get pKa of 4.
Glue E and Asp D both have 4 letters and are the only ones with PKA's around 4!!
Or they end in mate and tate and that's 4 letters which is close to PKA of 4.
Thanks for posting this! It was really helpful for memorizing the amino acids for my organic chemistry final
Pka 4.1, glue is 4 letters. As long as you remember that those are the two for which you use the 4 letter trick thing.
How I remember Aspartic Acid having a D as its one letter abbreviation is thinking of Aspartic acid as AsparDic acid. And For lysine, I think of LyKsine so its one letter abbreviation would be K for lysine. Hope that helps.
THis helped me a LOT, big ups for you and those that helped.
This is literally the best thing ever.
This video is awesome, but could you add hydrogens to histidine and Arginine?
Hello my trick to remembrer the Pka of D and E is that D is the forth letter of the alphabet.
I remember the PKa of Asp/Glu like this:
D is the 4th letter of the alphabet, = 4
E is the 5th letter; ONE higher than D = 1
Ergo, 4.1 :) Ty for the vids
For Arganine, I just think "ARG watches CNNN,"
Best amino acid lecture ever. Thanks!