Insulin resistance and why we get sick with Prof. Ben Bikman - Diet Doctor Podcast
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- Опубліковано 19 чер 2024
- Is too much insulin a root cause for the chronic diseases that plague modern society? According to Professor Ben Bikman, it likely is.
And he should know. Professor Bikman is a scientist and researcher who specializes in insulin and its effects on our health.
In his new book, Why We Get Sick, Dr. Bikman makes a case for why we need to target insulin levels to improve global health. As you’ll hear him say, lifestyle choices can cause insulin resistance, and they can cure it, too. The tools are at our disposal; we just need to know what they are and how to use them.
Dr. Bikman speaks with a combination of authority and humility that’s rare in today’s world of soundbites. I appreciate his expertise and his approach, and I hope you will as well.
Table of content
0:00 Introduction
2:15 Welcome, Prof. Ben Bikman
3:34 A dissenting voice between the medical and research community
5:01 How Ben defines insulin resistance
7:06 Insulin resistance in different cells of the body
11:12 You can't have insulin resistance without hyperinsulinemia
12:14 Some basic functions of insulin
15:13 Common threats that insulin has in its function
18:25 Level of evidence linking high insulin to diseases
22:52 Insulin resistance and its part in most chronic diseases
30:41 Beta cell failure in type 2 diabetes
33:15 The primary and secondary causes of insulin resistance
39:54 The types of food and eating frequency matter
41:45 Effect of saturated fat in muscle-insulin sensitivity
45:46 Condition of reversed metabolic flexibility
51:25 Exercise and insulin resistance
54:10 The types of exercise to combat insulin resistance
57:55 Is a low-carb diet the only way to reverse insulin resistance?
1:02:50 Fasting to improve insulin resistance
1:08:22 Where to find Prof. Bikman
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Went to my Endocrinologist today. I was put on a new condensed insulin and they have raised it till I am at 200 units now. I told my doc I gained 25 pounds in the last few months. She said there is nothing that can be done. I was discouraged until someone mentioned your book "Why We Are Sick." Just ordered it and looking forward to reading it
We also have a free two week getting started challenge on our website that you may find helpful!
www.dietdoctor.com/low-carb/get-started
how irresponsible. How can they not know that insulin would lead to weight gain or did they not even bother to tell you that might happen? That's been common knowledge since people started taking insulin for Type 1; they start gaining weight and it was considered a good thing because they were wasting away before. I'm glad you found out that something can be done before it becomes another health issue for you. Good Luck and Be well.
@@Metqa They told me obesity wasn’t as important as keeping my sugars down.
@@SharonH56 don't eat the carbs and sugar will stay down. It's like giving a person with a nut allergy peanuts and saying don't worry, just use your epipen
Weight lifting/building muscles is the ultimate key to reverse insulin resistance, NOT weight loss alone.
Take aways:
Intermittent fasting
Low carb low sugar high protein good fat diet
Movement/exercise
Reduce stress
Sleep well
Thank you both 🙏🏼
Good Summary
What foods?
Wrong conclusion - high protein was never discussed in this video. Only low carb was, and low carb does not automatically mean high protein.
Lppo
@anil study There was a recent clinical trial where Yoga was found to reduce the A1c (blood glucose average).
I was 343lbs in April of 2022, today I’m at 248 lbs. How? Learned about insulin. Started IF and cleaned up my diet. (As little sugar as possible, no bread, pasta etc and whole food’s only) 52m. 233lbs on 1/6/23
I’m 2.5 weeks if at my worst I was around 228 now at 173. Still
Have work to do but I am trying to learn as much as possible.
@@camsteremail Bikman is a great teacher.
On problems of prosperity: I grow all my own fruits and vegetables, and enough for relatives and neighbors to get some. Many days, I am outside 5-6 hours per day, moving compost or mulch, digging, tying up, weeding, mowing with a push mower, raking, turning compost. I also go fishing now and then. So much of my food is fresh, maximum nutrition, eaten or frozen within minutes or, at worst, hours of harvest. I get more Vitamin D from the sun than most. And there are mood-elevating chemicals in soil, they say, so I work glove-free and barefoot. Some years, I get a deer a relative has hunted. This year, I'm getting hens for eggs. With all my mind, heart, and body, I believe this is closer to what we're supposed to do, what our bodies are hardwired to do. Sitting in a cubicle for 9 hours and eating sugar most assuredly is not.
What a wonderful life you have crafted for yourself. Your family and friends are lucky to have you.
Let me remind you one thing if you haven’t realized…. Your happy life is give by the prosperity of the city or the country you are in….., right on top of others’ less happy life.
You need to realize many people don’t even have a yard to get the proper sunshine. My home doesn’t have a yard for vegetables at all, not to mention my job doesn’t give me any time to actually do it.
Humans have been around for 250,000 or so years. The subsistence agriculture you are engaged in has only been around for 10,000 or so years. Hunting and gathering our food in the wild is the true norm for most of our time as a species. :-)
I absolutely agree with you. Isn't it ironic how the more we "evolve" the less we do and know. Nothing will bring us the satisfaction of working for our own wellness xD
wow
Dr. Scher is a great interviewer. I said that before and I had to say it again.
Totally agree with you and love Ben Bikman too, so articulate .... both of them
Ben Bikman is one of the great modern heroes of our times. I wondered many times how many millions of lives will he save by shifting the paradigm on diabetes and the perception we have of insulin? Tens of millions? Hundreds? Certainly over time. Of course to that many others contribute, from health coaches to doctors and dietitians that similarly contributed to changing outdated attitudes in the medical establishment, but research professors have a special place among them for providing the explanations and the evidence all the rest use to proliferate the knowledge. His Children should be(and am sure they are) very proud of their father.
Either the world will wake up or they will be woken up - Metabolic disease is bankrupting healthcare and social security.
Amen
If you love to get a bit deeper into the how and why of things, this is by far the best health podcast on the planet. Cutting edge science explained by leaders in their field, presented by a world-class interviewer. For all the rot out there let us not take for granted what we have here. Thankyou Diet Doctor, guests and all those behind the scenes.
I enjoy Bikman. But I have to say some of this stuff is over my head. Trying to heal a fatty liver. Ugh
But how do you which one you are?
@@brendakemp9060 Low carb, no seed oils, no processed or junk food, healthy fats, and watch the fructose. Over eating fructose (which is 50% of our table sugar) is the quickest way to NAFLD. Best of luck.
@@brendakemp9060
What worked for me was NO GRAINS , NO FRUITS & NO POTATOES! Find your own carbohydrates threshold! It is below 100 gram per day .
I am doing fasting with low carb and it works.OMAD helps me with my insulin resistance. The key is I eat even less than I ate before now and much less carbs. I lowered my calorie intake. Feeling full is not easy when you have insulin resistance. So eating only once is much easier for me. I feel full and stop eating. So I eat half of what I was eating before I started OMAD. I eat very few carbs. I feel so good after around 18-19 hours of fasting. I am doing this to get rid of my insulin resistance and the infections that it is causing in my body.
Nice work, Karen…stay triggered 🥰
Me too. I had the same issue of never feeling satiated. OMAD/low carb works. And the weird thing? It’s not hard. Congratulations.
Keep it up, that strategy worked for me and I’m in my sixties. If I’m away from home or busy at mealtime, I look at it as great opportunity to extend my fast. I still have enough fat on my body to feed me for a while 🤣
@@skeptigal8899 it is me too! OMAD works for me!
@@skeptigal8899 you are lucky.
I'm very happy to listen to this podcast while fasting for 48hr, knowing both my insulin/glucose levels are super low. Amazing talk.
I’m 52 and have no medical education but I keep reading and studying this stuff trying to understand it more deeply. I wish I could help to get it out to more people even though I’m not qualified to do so. I’m carnivore 4 years and into mobility training, best way I can help is to live as an example.
The passion of both of these men is inspiring! Best interview I've seen in years.
totally agree
@@dmahadeo poker j on llama lol juju and
Dr. Scher is my favourite interviewer. He always know what to ask, when to ask and how to ask...so that we can understand the topic better. Thanks!
I can listen to professor Ben every day! 🎉 He is BRILLIANT❤
OMG. I just started reading Why we get Sick this a.m.! I also sent 2 copies to relatives❤
This is next on my list. I am reading or read Lies My Doctor Told Me, the Big Fat Surprise, The Case Against Sugar, Stall Slayer, The Salt Fix, and Why We Get Fat
@@AnnetteLG Why we get fat (Taubes) has been my favorite but I think Why We Get Sick might become my new favorite
@@tammyb8742 Yes, Taube's, why we get fat is a great book. I have to read dr. Ben's book now.
I do intermitent fasting.... And we are taught to never eat 4 hours before going to bed..... YES you have to have a plan to break the fast....AND I do it to control blood sugars.... 1 meal a day. and when it doesnt work, go back to mixing up my fasting plans.... LOVE this education.
Yesterday I had breakfast…rare for me anymore. I was actually hungry, like somatic hungry, not the I think I want to eat something tested my blood sugars, cause I thought I was going to get a sugar low. Diabetic in the process of reversal
Damn! This episode explained EVERYTHING that is going on with my diabetes, glucose monitoring, gaining fat etc... also explains the last 20 years of being very fit and still carrying 20-30 lbs of extra fat. Thanks y'all.
Dr Bikman is amazing
His book is fantastic. One of my favorites.
He’s very humble and very thoughtful
I think you need a second opinion. Take 7 minutes out of your day and listen to this guy. Easy to understand and the opposite opinion.ua-cam.com/video/7Ij0iyrdm2M/v-deo.html
@@ddhqj2023 how about if neither the vegan Dr, nor the carnivore/ keto Drs are wrong. From what I've gathered there are certain ingredients that should not be mixed together. I've heard of vegan and keto dieters have heart attacks, and I think is because they weren't truly vegan or keto, they were just trying to be, and were cheating allot. In addition, community, gratitude and genuine happiness are almost always under represented in these type of interviews. We need to be careful of reductionist thinking. Look up the oldest people on the planet, they are neither strict vegans or carnivore/keto, and actually, they lean slightly to more animal based diet. Google, what the oldest people in the world eat and drink everyday. Let me know your opinion. Is like to read your thoughts, and no I'm not being a smartass, I really would like to read your opinion. Thanks.
@@ddhqj2023 And one more thing, you have to admit that the Vegan Drs. never make the distinction between the type of fat that is found in grass feed grass finished beef vs grained feed beef, and that's not an irrelevant comparison. I've always wondered why they lump all of it together.
@@latinboyyy305 Why would they differentiate between grass fed fat or grain fed fat. It's all the same in that it contains bacteria that when cooked, turn into endotoxins, leak into your bloodstream and cause inflammation at the cellular level. And chronic inflammation is a precursor to various disease processes. Disease processes which over time, may morph into obesity, diabetes, heart disease, cancer, skin ailments, etc.
Dr Scher always asks great questions
Love Dr Bikman. Could listen to him talk for hours.
I am reading Dr. Bikman's book right now. This is a great interview with wonderful, life changing information being shared.
Thank you dr. Ben and dr. Bret. Excellent interview.
Professor Benjamin Bikman and Dr Sher are two of my favourite Teachers, thanks guys.
If I may add, Dr Paul Mason is very knowledgeable too.
@@vilmasarraf6895 Oh yes.
Awesome interview, thank you dr. Scher and prof. Bikman! Just a note: if you do time restricted eating/IF/OMAD combined with LC for a while a do it correctly, e. g. you are fat adapted, your hunger and cravings go away. When you then eat nutritionaly dense food and quality protein and fats, it is actually hard to overdo => satiating effect of protein and fat. Your hormones kick-in and your body tells you when to stop. You just have to watch for meal timing and like Prof. Bikman said, don’t eat right before bed. Finish at least 2 hours or more before sleeping.
Lol You summarized his book in one paragraph.🤗
@@2fixmj563 Thank you! ;-)
That's what I should try.
I have been doing OMAD for over two years with zero success. Sometimes I have two meals in 4 hours and fast for 20 hours.
In fact I think I have gained some weight and inches over the years with fasting.
I eat OMAD and do resistance workouts 3-4 times per week and do 30 min cardio immediately after resistance training, in addition in the last 5 weeks I walk for one hour at least five times per week. It would be great to see some progress finally :)
In not sure what I'm doing wrong.
Thank you.
@@EEEBA1 what are you eating?
Did you make any progress in the meantime?
@@chesscoachgerry4140 I stooped working out and doing cardio four months ago thinking I'm over doing it. I lost a few pounds that's all.
I'm back to eating almost everything meaning more carbs but still no fast food, soda, sweets etc. I really don't know why I couldn't lose fat for years.
It would be interesting to see a study on how hyperinsulinemia affects gut bacteria. I have a strong feeling that stuff like SIBO is very much something that is affected by high insulin levels, with insulin being the proliferator or growth factor. What do you think Dr. Bikman?
Wow! This is the first time Ive seen someone else thinking this too. Would love to hear this discussed.
that was great. Thank you both.. I rarely watch videos this long, this one was well worth it!
I also repeat...this is the best most informative dietary health channel on UA-cam or anywhere for the topics covered. Even in simple Google searches for text, Diet Doctor is simply the most on point purveyor of relative information of dietary concerns. The in depth information they provided makes it easy to decipher and understand fact from fiction. Many thanks...
Listened to Ben and read his book. Use a 6 hour eating window. Starting around noon. After many diets went low carb , med protein diet. Along with moderate exercise dropped 60 lbs in year. A1C now at 5.5 down from 5. 9
I know well Dr Jason Fung’s work but that’s the first time to watch Prof Bikman. I purchased his book on kindle and start reading immediately
The scenario that you mention at the end where OMAD becomes a mini binge was me when I first started. I knew it wasn't ideal, but it was better than eating ("sugar") all day and it was what I could manage at that time. Gradually it is improving as I get more educated and healthier, without me having to try really too hard. It's a mistake to assume our long term results will be based on how good or bad our plan is when we first start out. Do what you can, even if it's a little. If you have to promise yourself a high carb reward to get through your first ten 20- hour fasts, who cares? Just gradually keep trying to do better when you are able. As they say, the perfect is the enemy of the good.
I agree, I cut my sugar intake slowly over 3 years. I didn't have much of a plan only to cut it out completely at some point. Initially I would only buy packaged food with 20gsugar/100g, then after few months would only buy products with 10g sugar or less in 100g of the product. Finally it was less than a 5g sugar and then went down to 1 tsp/week. This wasn't overly difficult bearing in mind how addictive sugar can be.
The best and socially helpful channel on UA-cam or anywhere else . Period ... Thanks doc 👍
Omg... im an RN and budding freelance research writer.
I'm going to read all of your work! I would love to work with you one day. I'm over coming insulin resistance, fatty liver, losing weight, and ketovore/ IF daily. Down 33 lbs since March 19th. Battling cancer now, which as we all well know cancer is just metabolic disorder of the mitochondria....we've even sickened them with our SAD!
TYFS,
Jen
Great. Love Dr. Bikman. Great questions and focused discussion.
This is really great interview. Thanks to both of you.
I loved this talk so much. This answered all the questions I've had in my mind!
Thanks for both of you great interview
Dr Ben Bikman a fine thinker. I am highly enlightened. Keep it up.
Thank you Dr Bikman. You really educate me of how to take care of myself. I need to order book, WHY WE GET SICK. ALSO GIVE THANKS TO THE INTERVIER. YOU HAVE A GREAT KNOWLEDGE 👍. MAY GOD BLESS YOU BOTH.🙏💝💯
Discovering Prof Ben Bikman is like finding gold. Subscribing - great content. Grateful to my YT feed for this one! Off to buy the book too. Thank you for this interview.
Well vegetarianism didn't work for me for 20 years and sadly, keto carnivore even at 90% is what has helped me tremendously.
Just finished his book yesterday and used this to reinforce the info. Good interview. Passing it in to my kids.
Ben Bikman is awesome! Thank you so much for this information!
Fantastic interview! Thank you
Wow! Great interview. Thanks again. Well balanced info.
I love Ben Bikmen. His description of cells being overfed leading to insulin resistance explains why some people have weight loss stalls on low carb diets. To me, that seems like an important breakthrough.
I gotta say….. you’re both great guys! Thank you. 🙏🏼🙏🏼🙏🏼
This is one that I'll have to listen to more than once. Excellent!!
Dr. Bikman, thank you for this information. I am looking more into these concepts you are presenting. 😊
This discussion is a gem!
Loved this interview. So informative
Dr Scher und Dr.Bikman, great video
with all the problems of today and all the solution, it is so good, easy explained. Thanks from Germany
Eszter Horvath
Love me some Dr Bikman. He is so well informed 👍💪🧠
very helpful suggestions. i liked the "specifics" given . binging triggers explanation appreciated.
I would love to have Ben Bikman reconcile his research findings on the impact of insulin resistance on our bodies and metabolic syndrome plus other chronic diseases vs Dr. Rick Johnson’s research on the connection between fructose on uric acid and then on insulin resistance and metabolic syndrome. Bikman focuses on glucose and insulin while Rick Johnson focuses on both fructose and glucose, with uric acid being a key intervening factor.
I'd like to see a collaboration between Dr Bikman and Dr Lustig. That would be the best of both the research and clinical worlds.
So much relevant information about insulin. Thank you so much for doing what you do!
This guy is one of the best. I may actually get the book. I need to summarize what he says so I can influence family.
Thank God there are Doctors and scientists like Dr. Bikman because quite frankly this stuff bores me to death.
As a type II diabetic.......I am so happy there are people who have an interest in this.
This interview is extremely dense with information. It's almost mind boggling.
It was a very useful interview. Thanks for inviting Prof. Ben Bikman.
Was glad to hear Dr. Bikman say that IR is not THE factor of disease, but that it's an important link to causal effects of illness. I've watched podcasts that state he only focuses on IR, and now I know that's not the case. Dr. Bikman sees IR as a major player, and from what I see, that is certainly the case. His study of insulin is very telling, and needs those who can work with him from there.
Re Cortisol and insulin resistance. I recently had 5 days off travelling 3 hours to a beautiful country location and felt extremely relaxed. I noticed my fasting glucose went down by .6 mmol to 4.2 while away. As soon as I came back to the big smoke it went back up by .6 mmol to 4.8. My guess is Cortisol.
Cortisol I suspect is my greatest problem at the moment. I am a chronic insomniac and battling with minor autoimmune (rheumatoid arthritis) for many years now
@@dmahadeo have you tried a low carb diet?
@@scotchfillet For the last three and a half years generally. Went carnivore for three months a while back. The less carb I eat the higher I suspect my cortisol goes - heart racing, etc. But I am still committed to low carb. Been playing with electrolytes and minerals hoping to achieve some results
Very interesting. There's always more to learn about this topic.
Thank you, I enjoyed!!!
Spectacular interview; even the second time watching it!
You are an outstanding Scientist who has changed my life.I do appreciate your U-Tube very valuable information.I have also bought your book Why We Get Sick,from Amazon.
Your book is a gem for health seekers.
Thanks so much for sharing your deep knowledge and research on diabetes.
God bless you and your family.
Thank you. I've learnt so much.
Excellent, thank you very much !
Very good lads. Here’s as additional thought from my experience. Twelve months careful dieting wasn’t enough. When I added an 18/6 autophagy method, WOW. Every one is different I know but this was astonishing. Cheers Mike
Great, as always.
Thank you Both. So much great information..
I have his book and LOVE IT 🥰
These Gentlemen are saving mankind. Keep up the good work. You are saving many lives withought even knowing it. I am indebted to you.
As always I love Prof. Bikman's knowledge on insulin. I also brought his book. I just want to touch on OMAD. I have been doing intermittent fasting for decades. It used to called skipping meals. But anyway, I find that Your body don't allow OMAD Binge because you actual get fuller faster when eating OMAD. It is when you allow few hours of eating your OMAD that can cause binge. So, if you pile up a table full of food only eating as much as you can til you feel full, you will not binge comparing to allowing yourself few hours to eat a meal.
I read it, great book
Agree
Love Dr. Ben
Thank you both.
So over my head! I barely understand it. I'll need to watch several times. 😯
Wonderful interview. Thank you.
Yes, the paradigms must change both looking at the glucose/insulin problem and also the ROS/LDL problem. We must also understand transient receptor potential channels and how they play critical parts in all of these scenarios.
Super helpful in deepening my understanding of 'metabolic syndrome. thank you
This makes so much sense and explains so many things!
I was rolling with Ben, and I did not miss a step. Wish he could just kept going uninterrupted.
This is to me the best explanation of insulin resistant. I am 71 years old and still working to keep my body active and I'm trying to follow low carb diet socI can reduce some weight because of my knee problem and to keep my blood sugar level to normal as I have been on borderline high. Thanks for the informations and I am for sure will share this to those who need this eye opening topic.
Big Thank You❤️, Learn Volumes from this Podcast 🙏
Bikman is very good. It is so weird that some people actually put thumbs down on this
They probably work for the company who makes metformin. Lol!!
Bet they’re vegans!
Professional jealousy?
Great discussion, but y'all missed a big point. Keto/low carb eliminates the hunger problem.
I don't see how I could do int. fasting on a low fat high-carb diet - the hunger would kill me.
Eating fat on keto = no hunger. It's truly amazing. I bet most people are much more likely to fast more effectively if they eat keto (or low carb maybe) when they eat. One of you may have mentioned the hunger thing earlier, but it would have been great if one of you had brought it up on the keto/low carb vs low-fat-hi-carb and int. fasting section.
Lots of stuff to think about here. Thanks.
Great video,I love this video,
This is excellent at explaining type 2 diabetes.
at 5 min it finally starts
nice info
This podcast is right up there with #57!
As an RN for 41 years, now retired, my question is why do MDs not have continuing education that addresses new studies relating to this problem....? Do they not see that what they have been telling us to do for the last too many decades has not worked. No curiousity?? For shame!!!
Great practical advice
Another excellent interview. Thanks to you both.
I almost didn't listen to this one. Since I've heard Ben speak many times. Glad I did and will get the book to add to my low carb collection
It’s not just what you eat, it’s how often you eat. I wonder if the communities of people who ancestrally eat high carbohydrate diets also snack all day long. And I bet they’re not sitting behind their desks on their computers all day.
... excellent presentation.
Two lovely souls.
It seems that they both are truly interested in helping people!!!
Very good information. was not sleeping well and my work and life overall have been very stressful for the last 10 years. Luckily, my blood pressure is always normal and my lipid panels except LDL (slightly high) are also normal. What has worked for me to return to my normal pre prediabetes state has been 16/18 IF with two meals. On weekends, I can go for a whole day for one meal only. However, I do not want to lose any more weight, and I will stop the weekend 24. I find it very easy for me to do since even before learning I was prediabetic, I was skipping meals almost everyday and I am a small eater.
This is how I found out that I had hyperinsulinemia: After listening to a video with Jason Fung I decided to cut my carbs one day. My body reacted strongly the following night (heart racing, hunger, sweating, restlessness) and I had a strong episode of hypoglycemia the following morning (weakness, shakyness, more sweating). I do not take any medication to lower blood glucose and was never diagnosed diabetic (I haven't had my blood glucose checked in years). That episode of hypoglycemia that I was able to recognize easily as I am a nurse made me realize that I needed to really cut down my carbs and change my diet to lower and hopefully reverse my hyperinsulinemia. By the way, I am in my sixties and always had issues with controling a healthy body weight.
Have you reduced your hyperinsulinemia? I too have hypoglycaemic episodes.
@@kaygibson8942 I think I did but didn't get tested for it. After six months of a low carb diet my hb1C was at 5.1. I do not have any hypoglycemic episode anymore. But I have completely changed my diet and reduced my carbs to only vegetables, nuts, some fruits and sometimes some dairy but no more grains.
I have faith in Dr Bikman’s science. Stay the course Ben.
Great podcast
I disagree “we don’t get paid” with regards of us medical doctors. The physiology, pathology etc all part of medical school. Nothing stops docs continue to be curious , exercising a common sense . I connected dots on hyperinsulinaemia to HT, PCOS , Diabetes etc a while ago and really needed evidence ..
You are doing an amazing job guys !! So hard to get through minds and hearts, we need you … your links to your podcasts on our hospital website page now!