I'm impressed with the number of people taking the time to complain (sometimes quite angrily and bitterly) in the comments about the absence of slides without taking that same time to look in the description to find them. This is a common format to have the video of the presenter and then a separate link to the slides. It's beautiful how much high quality free educational materials are out there.
Hes a very good speaker and has good slides .... yes I agree .... {the audience seemed so disinterested .... like kids in school room chewing gum and throwing spitballs ....]
Yes thank you for saying this! It is so impressive how many people are angrily complaining about they're not being slides when there's a link in the description.
Dr. Attia is fuckin dope. I was critical after listening to him during an interview for the 1st time because he seemed cocky, but I misinterpreted his command of his overall knowledge base. He’s not cocky, he just knows his stuff. Much appreciated Doc, thank you 🙏
If you think Cholesterol and saturated fat are harmful, just look at Peter Attia, and Gary Traubes, they both look very healthy and strong for their age.
Just being healthy now is not the issue, the issue is what will a person's health be in 20-30 years. Nearly all long lived groups eat primarily plant food and little meat. The ancient Eskimo mummies were big time meat eaters and had significant atherosclerosis and osteoporosis.
Finally! Someone who can explain my problem to me.. Familiar hyper-lipidemia. Plant sterols, I've taken for years because I have suffered terrible side effects from Statins. Should I stop plant sterols? Hmmmm? Would love to have Dr. Attis as my physician!
I have had high cholesterol for years. In 2011 I finally had a check up with a cardiologist. I had a neck artery scan which showed at least with those arteries that my arteries were very close to normal after 20 years of cholesterol levels anywhere from 230 to 290. The doctor wanted to put me on statiins but I refused. My mom had problems on statins and I found after her death her brother also had muscle issues when on statins. I go in next month to have a cardio check up with a new doctor so it will be interesting to find out my results. I don't want to take the risk of taking statins if 2 close family members both had a reaction to them.
The food and beverage manufacturers tried pure fructose as a sweetener, but because it is not well tolerated by most individuals they dropped their efforts. Pure fructose is not well absorbed and ends up in the bowel where it is broken down by bacteria and causes bloating and gas. This may be why the HFCS group had higher trig levels than the pure fructose group. The glucose might aid the absorption of fructose.
Fructose can only be processed by the liver, not the bowel. This is how some people end up with non-alcoholic fatty liver, consuming too much fructose.
How about doing this again and this time let us see the diagrams and what it is you are talking about so we can identify with what you are talking about.
If you have a lot of free time to do so, there are a lot of detailed diagrams among the cholesterol posts on his blog. Nine parts, plus an intro post. peterattiamd.com/category/cholesterol-2/
So much important useful information, except the videographer missed the boat of not showing any of the visual slides. Why are you filming the audience and not the slides. Very frustrating.
18:50 " It is a disease of LipoProtiens " , Question : In the complete absence of inflammation are the lipoprotiens still a problem? And if not then it is NOT a disease of LP's but a disease of inflammation. Eskimos all had high blood lipids and essentially zero CardioV Disease
Good question. I find it hard to believe, that a mechanism so vital for life (the boat carrying the cargo to where it needs to go) is flawed from nature, and allows the LDL to penetrate the endothelium and deposit the cargo there. Reducing chronic inflammation seems to be the key, as I see it (be it caused by a bad diet or otherwise unhealthy lifestyle).
A trip to the grocery store tells me things are getting worse not better with the stuff they are calling food. Shop and eat wisely if you value your health.
Camera man, how about showing us what everyone can see, the screen? I am sure we can hear the speaker as well see whats on the screen since we are on Keto and our brains are now smarter. What say you?
Great talk to go along Dr. Attia's Cholesterol series of articles in his blog. It's a shame there were additional cameras to take different sections of the audience but not of the slides being presented, which would make this video more valuable.
i recommend you go to PLANT POSITIVE, for attia,s true motives behind his low carb promotion. its simply false and staturated fat and cholesterol are at the root of arterosclerosis
@@cypriano8763 P. Attia: *presents reams of evidence that shows it's not that simple* You: BUT PLANTS AND HE LIES Try contesting the evidence instead of just making shit up about the presenter.
@@cypriano8763 I'm not here debating keto. Again, it is not that simple and it only ever seemed that simple because counterevidence was suppressed. www.sciencedirect.com/science/article/pii/S0735109720356874 Also, side note, stop conflating source and makeup of diet. There are keto vegans and low-fat animal eaters.
Peter's comments and slides showing the comparison of glucose, fructose, and HFCS are confusing and inaccurate. Fructose on the slide should be re-labeled "sucrose" as he states when he first introduces it at 31.53. When questioned at 34:54 by someone in the audience about not seeing sucrose on the slide, he then states it is all fructose, which contradicts what he said earlier and makes no sense. Sucrose is 50% fructose and 50% glucose, not 100% fructose. If re-labeled as sucrose, the slide and what he says will make sense. Pure 100% glucose shows the lowest rise in triglycerides followed by sucrose (50% glucose & 50% fructose), followed by HFCS (45% glucose & 55% fructose). The villain is the fructose. The higher the percentage of fructose, the greater the increase in triglycerides. This is because 100% of the fructose is metabolized by the liver as opposed to only 20% of the glucose. The liver will convert the excess to fat and export it.
Hey +AncestryFoundation, I suggest that you put an "annotation" at the beginning of this video to highlight the link to Dr. Attia's slides. The link is there in the description, but a lot of people (including me) seem to be missing it.
You need a new camera man, he consintrates on you then the audience. Not once does he show the slides you are talking about. I would appreciate it if you show your diagrams instead of the audience or you all the time. Your lecture is great, but your slides would help it be more informative. Thank you.
I could live on twigs and I'd make a lot of cholesterol. I think that might be why I"ve lost my appendix and gall bladder like my mom and even my grandma lost her gallbladder at 90 back in 1995.
At the 10:05 mark, Dr. Attia makes a statement that on a molecule to molecule comparison basis phytosterols are far more atherogenic than cholesterol. Does anyone have a citation for any research studies supporting that statement? I have been looking for a research report supporting that, but all I can find are research study reports and journal articles proclaiming phytosterols and phytosterans as reducing atherogenic and CVD risk by reducing cholesterol.
We aren't supposed to "fixate" on the particle size, yet the sdLDL particles are evidence that something is wrong in our system. Sounds like that's exactly what I should be looking at if it's going to eventually kill me. If the particle count is up, more than likely they are the smaller and denser ldl - it's all related, it is in my blood labs anyway. So the ultimate goal is to resolve/figure out what is causing this inflammation that is giving me the high Lp-PLA2 number that he refers to at the end of the presentation.
For those looking for more charts, diagrams and other visual details, there are nine blog posts with plenty of them: peterattiamd.com/category/cholesterol-2/
reliberal: this comment area doesn't allow web links; however, if you go to Slidesharet and type in Peter Attia in the search field, you should find the presentation.
Yeah - check out Dr Attia's series (the straight dope on C) on this topic in his blog - The Eating Academy - I found the slides I was looking for there Dr Attia - thanks for the work you are doing to make all of this understandable
As of 17 Nov 2017, "This account has been terminated due to multiple or severe violations of UA-cam's policy against spam, deceptive practices, and misleading content or other Terms of Service violations."
Dang! I was looking forward to this talk because I really admire Dr. Attia and have learned a lot from his videos. However, I only got about half way through this one because I found it impossible to follow without seeing the slides that he was constantly referencing. Why, oh why, would you put together this video and leave out half of the presentation - the slides? Please, please, as Emanuela Davis and others request below, can you possibly recut the video and include the slides?
High blood pressure, arterial stiffness dt AGEs, high fasting glucose to name a few risk factors. Also, particle count is more or less a probability game. The more particles you have flowing through your blood stream, the greater the risk one will get caught, become oxidized, and initiate the inflammatory process.
Excess sugar especially processed sugars, act like 'shards of glass' in our blood streams, this alone can tear arteral walls. I think Peter Attia should get together with Dr. J Bergman and Jason Fung. They would make a team no-one would go up against.
Click to 19:10. It seems this is due to an interruption in the intestinal epithelial wall. Once the gap junctions separate particles leak from the gut. Intestinal permeability...my understanding is this is a result of an inflammatory process.
I know your comment is a year old, but in case you see my comment...check out Ivor Cummins videos and research CAC scan/score. Calcium is the culprit, the body responds to inflammation and calcium gets put in the soft tissues, including blood vessels.
I had A STEMI Widowmaker in December of 2018, which stopped my heart for five mins. At the time I weighed 226, smoked 6-8 cigars a day and ate, on average, 2 pounds of candy a day. I stopped all that, dropped carbs, processed food, and most sugar. I don't to any HFCS. My LDL-P is 2286. WTF? I I'm having a hard time finding a cardiologist who hasn't had the Kool-Aid. I need to give somebody I can trust on this. I'm 62 years old male. Any suggestions on where to turn?
So not once in there did I hear why having more cholesterol is better. I heard why processed sugar and in particular fructose is bad. I heard some fantastic biochemistry and general information about why the medical community needs to talk with more nuance about cholesterol and the many molecules that mediate its use, transport, and absorption. Dr. Attia seems to know his information extraordinarily well, especially when it comes to the aging literature. However, I have never gotten a satisfactory answer for his and Dr. Rhonda Patrick's preference of the ketogenic/paleo diet, which I am assuming is who this talk was aimed toward. The keto diet does seem to be optimized for those struggling with mental health issues such as epilepsy, MS, and potentially some variants of Alzheimer's and dementia. But I don't understand why it is advocated from these researchers as a full-time diet. The best I've gotten is that it is mimetic of fasting mechanisms. However, I feel like Dr. Longo's (ua-cam.com/video/evGFWRXEzz8/v-deo.html), Dr. Fung's (ua-cam.com/video/jXXGxoNFag4/v-deo.html), and Dr. Panda's (ua-cam.com/video/iywhaz5z0qs/v-deo.html) fasting regimes convey most of these benefits anyway, particularly Dr. Longo's prolonged (5-day) fasting mimicking diet. I could see going into a ketogenic state to metabolically challenge the body and keep the metabolic system adaptive. That kind of hormetic stressor seems like it could be beneficial for the body every once in awhile. But their are so many rebound effects if you slip off the diet. Since you are essentially triggering the same mechanisms as fasting. I am primarily concerned because quite a bit of research seems to be pointing toward animal proteins having higher proportions of leucine which triggers the mTor pathway. And most of the mainstream adherents of keto lean heavily on dairy and meats. There are primarily plant-based keto diets but they still come with the same rebound problems if people don't adhere to them strictly and wean off of them when they transition out. I feel like there is a place for a ketogenic diet, but I don't know that it is as a long term feeding strategy. I feel like a pescatarian, wholly plant-based, or 2 day a week omnivore would be the best long term plan, particularly focusing on complex carbohydrates from vegetables and legumes with limited amounts from grains and simpler starches, such as white potatoes. This way you get plenty of fiber to trigger satiety, nurture a complex microbiome, and get a well-balanced range of micronutrients.
I worry more about pollutants in food instead of cholesterol so I would prefer to limit my wild seafood to either monthly or zero (just rely on vitamin b12 supplements). The healthier pre industrial food can no longer be replicated bec of overpopulation and pollutants are now everywhere even in antarctica and each of the food items we consume have to be evaluated for benefits and risks using current science. The war time or post war time healthy okinawa diet is also hard to replicate now.
So the question is, how do we get this information to the mainstream. The ones preached too to, 'eat your healthy grains, the food pyramid and myplate & low fat, etc...'? I love the videos by Dr. Attia, Dr. Patrick, Dr. D'agostino, and so many others but, sadly, they are preaching to the choir.
Forgive me for not having 39minutes to watch the entire presentation. I'm currently on a Ketogenic diet. Do I have to worry about cholesterol or not? I'm eating meats heavy in fat mostly every day.
You do *not* have to worry about cholesterol on a ketogenic diet (or any other diet for that matter). Cholesterol never was the problem, and your own body makes a lot more cholesterol than you consume with your food.
Cholesterol is present whenever there is inflammation, so it may be a marker, but it's not the cause. The biggest culprits of chronic inflammation are highly processed carbohydrates (sugar, flour etc.), excess consumption of omega-6 vegetable oils (soybean, sunflower etc). Low magnesium can play a role. The reason cholesterol and saturated fat were demonized in the past is most likely because cholesterol is *always* present when inflammation is happening, so it was misunderstood. Cholesterol doesn't cause the inflammation, it always comes to heal. Are we going to blame firemen for starting the fire just because we see them every time there is a fire? Cholesterol is so important for your health that your body produces most of it. You *do not* have to worry about the cholesterol that comes with your food. If you eat less, your body just makes more.
Vegans are healthier *than people who eat fast food and junk* (i.e. the SAD) which isn't very hard to do. Other than that they are not healthier than anybody else. And they don't live longer either. Please, spare me the vegan propaganda. Thank you!
Unprocessed food omnivore diet will probably be more popular if it can help prevent hair loss & can help grow hair. The government has no minimum requirement for cholesterol so I don't go out of my way to get more cholesterol. I am still getting some cholesterol in my diet from my weekly seafood (wild clams usually). My guess is it is safer to let the body make the cholesterol as needed to avoid too much cholesterol. Have not heard much about many people having trouble making cholesterol.
Most of the World outside the U.S. & U.K. (and Keyes influence) worries about too little cholesterol. Cell walls and hormones are made of cholesterol. 150 is the minimum desired blood level, and 200-250 is optimal. 400+ simply means you are eating artery-lining-destroying foods, like Canola Oil (GMO Rapeseed Oil); Industry studies showing it is 'heart healthy' are VERY short term: test is usually just 3 hours after consumption of a spoonful; & NOT after 3 years of frequent use. MSG ('natural flavors') and Citric Acid (a corn product) can put holes in things, too. High cholesterol (>>250? ) is just a sign of long term arterial inflammation. Body coats inflamed areas and holes in the Endothelial lining with it, like a scab. Lowering cholesterol artificially without addressing the cause of the inflammation (low grade mutated HHV-family viral infection?) increases 'all-cause' mortality, but doctors rarely read the original medical studies. Nor studied the newer viruses until recently: Cincinnati EBV April 2018 study, linking it to 94+ chronic diseases. Almost every adult worldwide now carries at least one strain of EBV (HHV-4) semi-dormantly. Dietary cholesterol has little to no relation to blood cholesterol. High triglycerides and a 'fatty' clogged liver-filter is what we do need to worry about! Need low fat, high phytonutrient & high antioxidant diet to reverse it. It will also reverse HBP/LBP, which is the body adapting or not adapting to the liver being clogged. Most current BP Meds do not detox or unclog the liver and fix the underlying problem. So eat your colorful (organic) fruits, berries, greens, herbs, spices, and vegetables, just like your grandma always told you! If she had a garden in the back yard, she probably lived into her 90s, despite smoking, etc. Need to temporarily lower the amounts of meats, fats, eggs, butter, nuts, and seeds, IF you have 'fatty liver' (rounded tummy), HBP, or diabetes, until your liver heals. Also need to cut down on mucus-causing foods, like dairy, gluten, soy, corn products, anything GMO or processed, plus any animal (esp. pork), fowl, or farmed fish fed GMO foods (grains, kibble). Mucus can clog the liver. The inflammed & clogged liver-filter eventually becomes 'insulin resistant'. Processing excessive or toxic fats stresses the clogged liver-filter, and therefore your guts (via bile), kidneys, heart & brain (via blood), and muscles & skin (via lymph); which is where a clogged 'fatty' liver sends the toxins it can't absorb or process. Since everyone is different, if very low carb Atkins or Keto hasn't cured you of (whatever annoys you) within 3 months, try
Re: environment: Women's fertility levels are dropping each decade, and menses are coming earlier and earlier. Age 14 was normal 50 years ago; now it is often around 9. In +40 years, it will be age 5 with 50% fewer successful pregnancies. Too many phytoestrogens in the environment? In GMO soy? Dairy? 'Processed' B.C. pills in the water supply? ...Male fish are disappearing from our rivers, too. Not sure if more men going bald is related, although whacky hormone levels and Alopecia (from the toxins) may be. Cancer cure rates have not improved in the past 70 years, and now 1 in 3 adults and pets get cancer. Pre-industrial age, it used to be VERY rare. For-profit Big Corporations feed and medicate both. Lower fertility sure beats a plague for God-given population control. Our World does need less people, and more natural unpolluted wilderness, rivers, and farms in order to be sustainable.
this is pretty hillarious. I've listened to a lot of Attia, and u get about the same info every time--elaborate intelligent descriptions, conclusion--unknown. In this case Attia ends--if u have a large # of particles (cholesterol)--which everybody that consumes high fat does(a fact Attia omits)--does it matter? Attia--I don't know. Should have opened with that doc. would provide better perspective on the info given.
He's elaborating on one of the major questions for low carb / ketogenic diets. Why is it that so many bio-markers can drastically improve but one of them usually gets worse. For what it's worth, a year and a half into a ketogenic diet and my LDL-C and LDL-P have both gone down from when I started, so your statement that "everything that consumes high fat does" is a false absolute. You might also look up Dave Feldman. Interesting stuff.
@@Xilixsys i've looked extensively at Feldman, an early heart attack candidate. Feldman is so full of it--trying to justify his through the roof chloesterol readings. as to ur diet markers,depends on were u started. Nothing Attia said supports high fat diet.
@@ratherrapid so why is Feldman ‘full of it’? He demonstrates with his N=1 experiments, which have been broadcast live by the way, that you can get your ldl down extremely low by eating an extremely poor diet. Looks to me like it’s you trying to justify your view which isn’t the same as Feldmans. So please explain why you think he’s incorrect!
@@paulg687 i quit Feldman vids about two years ago. my post, instead of stating Feldman is "incorrect" implies that Feldman is disingenuous. At that time his chloesterol readings were extremely high and his schickt was that the high readings are without consequence to cardiovascular health. I quit Feldman when i became convinced from other sources that high chloesterol is indeed a serious threat to heart health, contrary to Feldman at that time.
@@ratherrapid yeah ok, but why do you think he was disingenuous? He literally demonstrates your ldl can seriously be brought down in a week by a terrible diet. Conversely a better diet raised it. His experiment and its results are irrefutable and it was done in real time and predicted upfront. One of his main arguments was that cholesterol wasn’t the real reason for ldl - its triglyceride delivery. Do you believe that to be incorrect? Which bit specifically were you unhappy with?
I imagine 99% of the people in the YMCA audience went home and when asked what he talked about said "blah, blah, blah, colesterol is good for you" They likely couldn't even follow the bouncer and ticket taker part because of the severe sugar withdrawls they were going through from not eating for 39 minutes.
Stop concentrating on LDL-C and worry more about LDL-P. Cholesterol is not the cause of CVD. (BTW, we've known that since the 1960's--but Ancel Keys got his diet-heart hypothesis on the radar and got everyone worked up about cholesterol. A much better indicator of risk is the patient's ratio of trigs to HDL, and if you want a _real_ measure of CVD, order a CAC scan.) We know now that Keys cherry-picked the seven countries that supported his diet-heart hypothesis from among the twenty-two he measured. Harcombe's reanalysis of his total data failed to show any correlation at all. No subsequent study, including Keys' own Minnesota Coronary Study, has ever verified a correlation between cholesterol and heart disease. In fact, several studies, in particular the Women's Health Initiative and the Framingham data, show an inverse correlation between LDL and heart disease, particularly in the elderly. Not only that, but recently-published sugar industry memos have revealed that the sugar industry paid off several Harvard researchers, including Stare and Willet, to demonize saturated fat in order to take the focus off of sugar. If you want references to the relevant studies, take a look at _Good Calories, Bad Calories,_ by Gary Taubes (2007) and _The Big Fat Surprise,_ by Nina Teicholz (2014). It's a sad commentary on the state of nutrition science that investigative reporters know more about the actual science than "experts" in the field.
I'm impressed with the number of people taking the time to complain (sometimes quite angrily and bitterly) in the comments about the absence of slides without taking that same time to look in the description to find them. This is a common format to have the video of the presenter and then a separate link to the slides. It's beautiful how much high quality free educational materials are out there.
that's all fine and dandy if you can sync up the slide to what he's speaking about (in ones mind) ... i could care less about audience reaction.
instead of showing "audience reactions" , it would be much more useful to show the slides he's talking about. No ? Is it just me ?
mdesm2005 ... see the description
How do I know which slide to follow Smart Paul Geno
I was thinking the exact same thing. Would really have preferred to see the slides instead of the audience.
Hes a very good speaker and has good slides .... yes I agree .... {the audience seemed so disinterested .... like kids in school room chewing gum and throwing spitballs ....]
Link to the slides is in the description.
Pull up the slide deck (linked above) in a separate tab and watch it simultaneously.
Thank you!!!
Thank you thank you thank you for saving this presentation for me!
Yes thank you for saying this! It is so impressive how many people are angrily complaining about they're not being slides when there's a link in the description.
RIP mobile users
Thank you!!! 😊
to make it really simple adopt high fat, moderate protein and low card or NO carb at all.
Dr. Attia is fuckin dope. I was critical after listening to him during an interview for the 1st time because he seemed cocky, but I misinterpreted his command of his overall knowledge base. He’s not cocky, he just knows his stuff. Much appreciated Doc, thank you 🙏
he is a cocky mfer, surgeons usually are. But he knows his stuff.
You can tell this guy is crazy smart.
If you think Cholesterol and saturated fat are harmful, just look at Peter Attia, and Gary Traubes, they both look very healthy and strong for their age.
Just being healthy now is not the issue, the issue is what will a person's health be in 20-30 years. Nearly all long lived groups eat primarily plant food and little meat. The ancient Eskimo mummies were big time meat eaters and had significant atherosclerosis and osteoporosis.
John, you are "spouting ignorant paleo propaganda" what is your evidence that Okinawans, Adventists eat more meat than SAD? Clearly you are wrong.
Finally! Someone who can explain my problem to me.. Familiar hyper-lipidemia. Plant sterols, I've taken for years because I have suffered terrible side effects from Statins. Should I stop plant sterols? Hmmmm? Would love to have Dr. Attis as my physician!
I have had high cholesterol for years. In 2011 I finally had a check up with a cardiologist. I had a neck artery scan which showed at least with those arteries that my arteries were very close to normal after 20 years of cholesterol levels anywhere from 230 to 290. The doctor wanted to put me on statiins but I refused. My mom had problems on statins and I found after her death her brother also had muscle issues when on statins. I go in next month to have a cardio check up with a new doctor so it will be interesting to find out my results. I don't want to take the risk of taking statins if 2 close family members both had a reaction to them.
The food and beverage manufacturers tried pure fructose as a sweetener, but because it is not well tolerated by most individuals they dropped their efforts. Pure fructose is not well absorbed and ends up in the bowel where it is broken down by bacteria and causes bloating and gas. This may be why the HFCS group had higher trig levels than the pure fructose group. The glucose might aid the absorption of fructose.
Fructose can only be processed by the liver, not the bowel. This is how some people end up with non-alcoholic fatty liver, consuming too much fructose.
How about doing this again and this time let us see the diagrams and what it is you are talking about so we can identify with what you are talking about.
There is a version with diagrams. It's called "Dr Peter Attia - The Straight Dope on Cholesterol". It's by drcldrcl.
the description has the link to the slides: slidesha.re/WJCokS
Emanuela Davis 41,689
version with diagrams
www.mymwg.com/forums/threads/dr-peter-attia-the-straight-dope-on-cholesterol-video.535/
If you have a lot of free time to do so, there are a lot of detailed diagrams among the cholesterol posts on his blog. Nine parts, plus an intro post.
peterattiamd.com/category/cholesterol-2/
So much important useful information, except the videographer missed the boat of not showing any of the visual slides. Why are you filming the audience and not the slides. Very frustrating.
I would love to have seen the presentation he is pointing at all the time... Very interesting anyways! Thank you, much Love
so reading 1 sentence of the description is too much but ofc u would look at the slides
Wonderful presentation! Highly motivated speaker and lots of information and science data. Success!
18:50 " It is a disease of LipoProtiens " , Question : In the complete absence of inflammation are the lipoprotiens still a problem? And if not then it is NOT a disease of LP's but a disease of inflammation. Eskimos all had high blood lipids and essentially zero CardioV Disease
Good question. I find it hard to believe, that a mechanism so vital for life (the boat carrying the cargo to where it needs to go) is flawed from nature, and allows the LDL to penetrate the endothelium and deposit the cargo there. Reducing chronic inflammation seems to be the key, as I see it (be it caused by a bad diet or otherwise unhealthy lifestyle).
show the slides instead of looking at him.
or instead of looking at the audience
I have to agree. If he wasn't so pretty to look at I would not have made it through the video without the slides.
A trip to the grocery store tells me things are getting worse not better with the stuff they are calling food. Shop and eat wisely if you value your health.
Dr. Attia, I would love to have you as a guest on my podcast. It's so important that people understand the truth about cholesterol!
Filming the crowd detracts in a major way from this fine presentation. Please refrain in the future.
Thank you from the bottom of my heart
great talk. Gotta love Dr. Attia!
Link to the Slides in the description : slidesha.re/WJCokS
Camera man, how about showing us what everyone can see, the screen? I am sure we can hear the speaker as well see whats on the screen since we are on Keto and our brains are now smarter. What say you?
🤣🤓👩💻 🧠
Great talk to go along Dr. Attia's Cholesterol series of articles in his blog. It's a shame there were additional cameras to take different sections of the audience but not of the slides being presented, which would make this video more valuable.
i recommend you go to PLANT POSITIVE, for attia,s true motives behind his low carb promotion. its simply false and staturated fat and cholesterol are at the root of arterosclerosis
@@cypriano8763
P. Attia: *presents reams of evidence that shows it's not that simple*
You: BUT PLANTS AND HE LIES
Try contesting the evidence instead of just making shit up about the presenter.
@@thefisherking78 plant positive destroys that guy. Keto is a dumb diet period
@@cypriano8763 I'm not here debating keto. Again, it is not that simple and it only ever seemed that simple because counterevidence was suppressed.
www.sciencedirect.com/science/article/pii/S0735109720356874
Also, side note, stop conflating source and makeup of diet. There are keto vegans and low-fat animal eaters.
Peter's comments and slides showing the comparison of glucose, fructose, and HFCS are confusing and inaccurate. Fructose on the slide should be re-labeled "sucrose" as he states when he first introduces it at 31.53. When questioned at 34:54 by someone in the audience about not seeing sucrose on the slide, he then states it is all fructose, which contradicts what he said earlier and makes no sense. Sucrose is 50% fructose and 50% glucose, not 100% fructose. If re-labeled as sucrose, the slide and what he says will make sense. Pure 100% glucose shows the lowest rise in triglycerides followed by sucrose (50% glucose & 50% fructose), followed by HFCS (45% glucose & 55% fructose). The villain is the fructose. The higher the percentage of fructose, the greater the increase in triglycerides. This is because 100% of the fructose is metabolized by the liver as opposed to only 20% of the glucose. The liver will convert the excess to fat and export it.
Excellent point. But I take it that this is still in line with the bottom-line of Attia's argument, right?
All very well and good. But where does one find a primary care physician in Canada who knows or even cares about such things?
the slides are linked in the description dont trash the poor cameraman
Why do you show us the audience on occasion but not the slides?
Hey +AncestryFoundation, I suggest that you put an "annotation" at the beginning of this video to highlight the link to Dr. Attia's slides. The link is there in the description, but a lot of people (including me) seem to be missing it.
that initial quote was from Bastiat. that man was a gift to humanity.
You need a new camera man, he consintrates on you then the audience. Not once does he show the slides you are talking about. I would appreciate it if you show your diagrams instead of the audience or you all the time. Your lecture is great, but your slides would help it be more informative. Thank you.
Please correct me if I'm wrong but doesn't gut health has a lot to do with atherosclerosis?
I could live on twigs and I'd make a lot of cholesterol. I think that might be why I"ve lost my appendix and gall bladder like my mom and even my grandma lost her gallbladder at 90 back in 1995.
Amen! I want the slides! They are there for a reason.
At the 10:05 mark, Dr. Attia makes a statement that on a molecule to molecule comparison basis phytosterols are far more atherogenic than cholesterol.
Does anyone have a citation for any research studies supporting that statement?
I have been looking for a research report supporting that, but all I can find are research study reports and journal articles proclaiming phytosterols and phytosterans as reducing atherogenic and CVD risk by reducing cholesterol.
check out Dr. Attia's blog where he's written about this exact topic: peterattiamd.com/the-straight-dope-on-cholesterol-part-i/
Sorry we cannot see the diagram you are talking about ,if you please make it visible thank you
We aren't supposed to "fixate" on the particle size, yet the sdLDL particles are evidence that something is wrong in our system. Sounds like that's exactly what I should be looking at if it's going to eventually kill me. If the particle count is up, more than likely they are the smaller and denser ldl - it's all related, it is in my blood labs anyway. So the ultimate goal is to resolve/figure out what is causing this inflammation that is giving me the high Lp-PLA2 number that he refers to at the end of the presentation.
Why are the slides or illustrations not shown?
For those looking for more charts, diagrams and other visual details, there are nine blog posts with plenty of them:
peterattiamd.com/category/cholesterol-2/
nice crowd shots..... wayyyyy more interesting than slides!
cant believe we cant see the slides!
Awesome - but where are the slides?
I'm not no kind of a medical doctor and I was wondering why they wouldn't show in the slides
Link to the slides is in the description.
Incredible presentation.
reliberal: this comment area doesn't allow web links; however, if you go to Slidesharet and type in Peter Attia in the search field, you should find the presentation.
Under the "About" tab, you can find the link to the slideshare.
Will Lp(a) and LP-PLA2 tell you the same thing on a blood panel? My Lp(a) is
If you are going to upload this; a splitscreen (with the slides) is vital. Some sites do this. This was embarassing.
Yeah - check out Dr Attia's series (the straight dope on C) on this topic in his blog - The Eating Academy - I found the slides I was looking for there
Dr Attia - thanks for the work you are doing to make all of this understandable
There's a version on UA-cam that also includes the slides. Search for the user drcldrcl.
As of 17 Nov 2017, "This account has been terminated due to multiple or severe violations of UA-cam's policy against spam, deceptive practices, and misleading content or other Terms of Service violations."
I couldn’t find this
Dang! I was looking forward to this talk because I really admire Dr. Attia and have learned a lot from his videos. However, I only got about half way through this one because I found it impossible to follow without seeing the slides that he was constantly referencing. Why, oh why, would you put together this video and leave out half of the presentation - the slides? Please, please, as Emanuela Davis and others request below, can you possibly recut the video and include the slides?
Crystal Plaid ... slides are in the description
He skipped a key point -- how does the LDL get through/under the epithelium in the first place?
High blood pressure, arterial stiffness dt AGEs, high fasting glucose to name a few risk factors. Also, particle count is more or less a probability game. The more particles you have flowing through your blood stream, the greater the risk one will get caught, become oxidized, and initiate the inflammatory process.
exactly!
Excess sugar especially processed sugars, act like 'shards of glass' in our blood streams, this alone can tear arteral walls. I think Peter Attia should get together with Dr. J Bergman and Jason Fung. They would make a team no-one would go up against.
Click to 19:10. It seems this is due to an interruption in the intestinal epithelial wall. Once the gap junctions separate particles leak from the gut. Intestinal permeability...my understanding is this is a result of an inflammatory process.
This is weak without the slides, I love Dr. Attia but this viewing is frustrating
Mark Strozier link to slides in the description
Would have been really good with the diagrams :/
Look in the description box. There's a link to the slides there. (Unfortunately I didn't notice until the end, so now I'll have to watch it again.)
we missed interesting slides
I would love to see the slides - can we get them from Dr. Attia?
Yes, when he points at slides but we can't see them, the video is much much less useful. Please post the slides. :-)
why can't I just download the slides? painful. stupid actually
Any idea what the takeaways are for coronary health? All I got out of it was "reduce carb intake to reduce triglycerides", but it's way over my head.
I know your comment is a year old, but in case you see my comment...check out Ivor Cummins videos and research CAC scan/score. Calcium is the culprit, the body responds to inflammation and calcium gets put in the soft tissues, including blood vessels.
What a good video!!! Thank you
I had A STEMI Widowmaker in December of 2018, which stopped my heart for five mins. At the time I weighed 226, smoked 6-8 cigars a day and ate, on average, 2 pounds of candy a day. I stopped all that, dropped carbs, processed food, and most sugar. I don't to any HFCS. My LDL-P is 2286. WTF? I I'm having a hard time finding a cardiologist who hasn't had the Kool-Aid. I need to give somebody I can trust on this. I'm 62 years old male. Any suggestions on where to turn?
There's one doctor I heard of, "Dr. Peter Attia". Google him
I can't stop watching this... this is so geeky.
What about the increase risks with animal protein and the cancer. If we eat more cholesterol we eat more animal protein
So not once in there did I hear why having more cholesterol is better. I heard why processed sugar and in particular fructose is bad. I heard some fantastic biochemistry and general information about why the medical community needs to talk with more nuance about cholesterol and the many molecules that mediate its use, transport, and absorption. Dr. Attia seems to know his information extraordinarily well, especially when it comes to the aging literature. However, I have never gotten a satisfactory answer for his and Dr. Rhonda Patrick's preference of the ketogenic/paleo diet, which I am assuming is who this talk was aimed toward.
The keto diet does seem to be optimized for those struggling with mental health issues such as epilepsy, MS, and potentially some variants of Alzheimer's and dementia. But I don't understand why it is advocated from these researchers as a full-time diet. The best I've gotten is that it is mimetic of fasting mechanisms. However, I feel like Dr. Longo's (ua-cam.com/video/evGFWRXEzz8/v-deo.html), Dr. Fung's (ua-cam.com/video/jXXGxoNFag4/v-deo.html), and Dr. Panda's (ua-cam.com/video/iywhaz5z0qs/v-deo.html) fasting regimes convey most of these benefits anyway, particularly Dr. Longo's prolonged (5-day) fasting mimicking diet. I could see going into a ketogenic state to metabolically challenge the body and keep the metabolic system adaptive. That kind of hormetic stressor seems like it could be beneficial for the body every once in awhile. But their are so many rebound effects if you slip off the diet. Since you are essentially triggering the same mechanisms as fasting.
I am primarily concerned because quite a bit of research seems to be pointing toward animal proteins having higher proportions of leucine which triggers the mTor pathway. And most of the mainstream adherents of keto lean heavily on dairy and meats. There are primarily plant-based keto diets but they still come with the same rebound problems if people don't adhere to them strictly and wean off of them when they transition out. I feel like there is a place for a ketogenic diet, but I don't know that it is as a long term feeding strategy. I feel like a pescatarian, wholly plant-based, or 2 day a week omnivore would be the best long term plan, particularly focusing on complex carbohydrates from vegetables and legumes with limited amounts from grains and simpler starches, such as white potatoes. This way you get plenty of fiber to trigger satiety, nurture a complex microbiome, and get a well-balanced range of micronutrients.
I worry more about pollutants in food instead of cholesterol so I would prefer to limit my wild seafood to either monthly or zero (just rely on vitamin b12 supplements). The healthier pre industrial food can no longer be replicated bec of overpopulation and pollutants are now everywhere even in antarctica and each of the food items we consume have to be evaluated for benefits and risks using current science. The war time or post war time healthy okinawa diet is also hard to replicate now.
Slide show is available on Slideshare
So the question is, how do we get this information to the mainstream. The ones preached too to, 'eat your healthy grains, the food pyramid and myplate & low fat, etc...'? I love the videos by Dr. Attia, Dr. Patrick, Dr. D'agostino, and so many others but, sadly, they are preaching to the choir.
Challenging to follow without my “medical books” is there a “cholesterol for dummies“ version please? Asking for a friend.
too bad we can't see the slides
This is so far over my head how did I get here
I want to see the slides!!!!
Why do the boats dump the cargo at the artery wall. You jump aroung the most important part.
I wanted to see the diagrams
Great talk, thanks for the video
Forgive me for not having 39minutes to watch the entire presentation. I'm currently on a Ketogenic diet. Do I have to worry about cholesterol or not? I'm eating meats heavy in fat mostly every day.
You do *not* have to worry about cholesterol on a ketogenic diet (or any other diet for that matter). Cholesterol never was the problem, and your own body makes a lot more cholesterol than you consume with your food.
DCD : Think this is funny, huh? Well, maybe you ought to do a bit of research before posting a misinformed comment. Thank you!
Cholesterol is present whenever there is inflammation, so it may be a marker, but it's not the cause. The biggest culprits of chronic inflammation are highly processed carbohydrates (sugar, flour etc.), excess consumption of omega-6 vegetable oils (soybean, sunflower etc). Low magnesium can play a role. The reason cholesterol and saturated fat were demonized in the past is most likely because cholesterol is *always* present when inflammation is happening, so it was misunderstood. Cholesterol doesn't cause the inflammation, it always comes to heal. Are we going to blame firemen for starting the fire just because we see them every time there is a fire? Cholesterol is so important for your health that your body produces most of it. You *do not* have to worry about the cholesterol that comes with your food. If you eat less, your body just makes more.
Vegans are healthier *than people who eat fast food and junk* (i.e. the SAD) which isn't very hard to do. Other than that they are not healthier than anybody else. And they don't live longer either. Please, spare me the vegan propaganda. Thank you!
Wrong again. Your information is outdated. DO YOUR RESEARCH!
I’d much rather see the diagrams than the audience
The Plant Positive UA-cam channel has lots of Attia's diagrams. Check it out.
should have put the camera on the power points
Thank you Richi
Thank you Stephen
The word 'meditated' in the slides should be 'mediated.'
Ok so how and why is athlerosclerosis caused by cholesterol.
May as well say the sin qua non of a broken arm is a cast. Like the cast causes the broken arm.
this guy looks like vin diesel.
Unprocessed food omnivore diet will probably be more popular if it can help prevent hair loss & can help grow hair. The government has no minimum requirement for cholesterol so I don't go out of my way to get more cholesterol. I am still getting some cholesterol in my diet from my weekly seafood (wild clams usually). My guess is it is safer to let the body make the cholesterol as needed to avoid too much cholesterol. Have not heard much about many people having trouble making cholesterol.
Most of the World outside the U.S. & U.K. (and Keyes influence) worries about too little cholesterol. Cell walls and hormones are made of cholesterol. 150 is the minimum desired blood level, and 200-250 is optimal.
400+ simply means you are eating artery-lining-destroying foods, like Canola Oil (GMO Rapeseed Oil); Industry studies showing it is 'heart healthy' are VERY short term: test is usually just 3 hours after consumption of a spoonful; & NOT after 3 years of frequent use. MSG ('natural flavors') and Citric Acid (a corn product) can put holes in things, too.
High cholesterol (>>250? ) is just a sign of long term arterial inflammation. Body coats inflamed areas and holes in the Endothelial lining with it, like a scab. Lowering cholesterol artificially without addressing the cause of the inflammation (low grade mutated HHV-family viral infection?) increases 'all-cause' mortality, but doctors rarely read the original medical studies. Nor studied the newer viruses until recently: Cincinnati EBV April 2018 study, linking it to 94+ chronic diseases. Almost every adult worldwide now carries at least one strain of EBV (HHV-4) semi-dormantly.
Dietary cholesterol has little to no relation to blood cholesterol.
High triglycerides and a 'fatty' clogged liver-filter is what we do need to worry about!
Need low fat, high phytonutrient & high antioxidant diet to reverse it.
It will also reverse HBP/LBP, which is the body adapting or not adapting to the liver being clogged. Most current BP Meds do not detox or unclog the liver and fix the underlying problem.
So eat your colorful (organic) fruits, berries, greens, herbs, spices, and vegetables, just like your grandma always told you! If she had a garden in the back yard, she probably lived into her 90s, despite smoking, etc.
Need to temporarily lower the amounts of meats, fats, eggs, butter, nuts, and seeds, IF you have 'fatty liver' (rounded tummy), HBP, or diabetes, until your liver heals. Also need to cut down on mucus-causing foods, like dairy, gluten, soy, corn products, anything GMO or processed, plus any animal (esp. pork), fowl, or farmed fish fed GMO foods (grains, kibble). Mucus can clog the liver.
The inflammed & clogged liver-filter eventually becomes 'insulin resistant'.
Processing excessive or toxic fats stresses the clogged liver-filter, and therefore your guts (via bile), kidneys, heart & brain (via blood), and muscles & skin (via lymph); which is where a clogged 'fatty' liver sends the toxins it can't absorb or process.
Since everyone is different, if very low carb Atkins or Keto hasn't cured you of (whatever annoys you) within 3 months, try
Re: environment:
Women's fertility levels are dropping each decade, and menses are coming earlier and earlier. Age 14 was normal 50 years ago; now it is often around 9. In +40 years, it will be age 5 with 50% fewer successful pregnancies.
Too many phytoestrogens in the environment? In GMO soy? Dairy? 'Processed' B.C. pills in the water supply?
...Male fish are disappearing from our rivers, too.
Not sure if more men going bald is related, although whacky hormone levels and Alopecia (from the toxins) may be.
Cancer cure rates have not improved in the past 70 years, and now 1 in 3 adults and pets get cancer. Pre-industrial age, it used to be VERY rare. For-profit Big Corporations feed and medicate both.
Lower fertility sure beats a plague for God-given population control.
Our World does need less people, and more natural unpolluted wilderness, rivers, and farms in order to be sustainable.
From the look at the audience I'm not the only one that don't have a clue of what he's talking about 😆
Could we please see the slides instead of the audience ? !!!!
These thumbs down must be from medical professionals supporting statins, means billions of profits.
The Irish guy corrected the great one.
..Get in !!!
What about LP(a) ?
OK, cameraman, what's the fascination with the audience?
Two years in a row now that they dont film the slides...
24:22 That's what she said.
when you going to come to oregon to do speech ? peter attia ?? please come to oregon if need place to stay it free for you sir
this is pretty hillarious. I've listened to a lot of Attia, and u get about the same info every time--elaborate intelligent descriptions, conclusion--unknown. In this case Attia ends--if u have a large # of particles (cholesterol)--which everybody that consumes high fat does(a fact Attia omits)--does it matter? Attia--I don't know. Should have opened with that doc. would provide better perspective on the info given.
He's elaborating on one of the major questions for low carb / ketogenic diets. Why is it that so many bio-markers can drastically improve but one of them usually gets worse.
For what it's worth, a year and a half into a ketogenic diet and my LDL-C and LDL-P have both gone down from when I started, so your statement that "everything that consumes high fat does" is a false absolute.
You might also look up Dave Feldman. Interesting stuff.
@@Xilixsys i've looked extensively at Feldman, an early heart attack candidate. Feldman is so full of it--trying to justify his through the roof chloesterol readings. as to ur diet markers,depends on were u started. Nothing Attia said supports high fat diet.
@@ratherrapid so why is Feldman ‘full of it’? He demonstrates with his N=1 experiments, which have been broadcast live by the way, that you can get your ldl down extremely low by eating an extremely poor diet. Looks to me like it’s you trying to justify your view which isn’t the same as Feldmans. So please explain why you think he’s incorrect!
@@paulg687 i quit Feldman vids about two years ago. my post, instead of stating Feldman is "incorrect" implies that Feldman is disingenuous. At that time his chloesterol readings were extremely high and his schickt was that the high readings are without consequence to cardiovascular health. I quit Feldman when i became convinced from other sources that high chloesterol is indeed a serious threat to heart health, contrary to Feldman at that time.
@@ratherrapid yeah ok, but why do you think he was disingenuous? He literally demonstrates your ldl can seriously be brought down in a week by a terrible diet. Conversely a better diet raised it. His experiment and its results are irrefutable and it was done in real time and predicted upfront. One of his main arguments was that cholesterol wasn’t the real reason for ldl - its triglyceride delivery. Do you believe that to be incorrect? Which bit specifically were you unhappy with?
why aren't you showing the charts, it doesn't feel good when we're excluded like that,
Did i miss his comments on 'statins' ?
I imagine 99% of the people in the YMCA audience went home and when asked what he talked about said "blah, blah, blah, colesterol is good for you" They likely couldn't even follow the bouncer and ticket taker part because of the severe sugar withdrawls they were going through from not eating for 39 minutes.
You don't know anything about them. You just want to be a dick.
Awesome.
The cameraman used to work at Stand Up's, kek.
I m a medical doctor but I got very little what he said. What's the take away message ??
Stop concentrating on LDL-C and worry more about LDL-P. Cholesterol is not the cause of CVD. (BTW, we've known that since the 1960's--but Ancel Keys got his diet-heart hypothesis on the radar and got everyone worked up about cholesterol. A much better indicator of risk is the patient's ratio of trigs to HDL, and if you want a _real_ measure of CVD, order a CAC scan.)
We know now that Keys cherry-picked the seven countries that supported his diet-heart hypothesis from among the twenty-two he measured. Harcombe's reanalysis of his total data failed to show any correlation at all. No subsequent study, including Keys' own Minnesota Coronary Study, has ever verified a correlation between cholesterol and heart disease. In fact, several studies, in particular the Women's Health Initiative and the Framingham data, show an inverse correlation between LDL and heart disease, particularly in the elderly. Not only that, but recently-published sugar industry memos have revealed that the sugar industry paid off several Harvard researchers, including Stare and Willet, to demonize saturated fat in order to take the focus off of sugar. If you want references to the relevant studies, take a look at _Good Calories, Bad Calories,_ by Gary Taubes (2007) and _The Big Fat Surprise,_ by Nina Teicholz (2014). It's a sad commentary on the state of nutrition science that investigative reporters know more about the actual science than "experts" in the field.