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That’s a great question! In organic chemistry, "ONs" refers to a sulfonate leaving group, where the sulfur atom acts as the leaving group; essentially, it's a sulfur-based group that readily departs from a molecule during a nucleophilic substitution reaction due to its ability to stabilize the negative charge through resonance, making it a good leaving group!
How did you do? I'd love to hear your proposals for next week's mechanism so drop them down below! Subscribe for more chemistry content, and hit the notification bell to stay updated! #ScienceCommunity #MechanismMonday #OrganicChemistry
Nice
Thanks! You were first!
fyi the scheme in the white box has the wrong product drawn. i was confused looking at the thumbnail before watching this.
Haha. Great catch!
What ONs stands for? ON2? I think I don't know this leaving group.
That’s a great question! In organic chemistry, "ONs" refers to a sulfonate leaving group, where the sulfur atom acts as the leaving group; essentially, it's a sulfur-based group that readily departs from a molecule during a nucleophilic substitution reaction due to its ability to stabilize the negative charge through resonance, making it a good leaving group!
Its a nosyl group, similar to tosyl except its para nitro instead of paramethyl.
But tBuOk is bulky base so grabbing an acidic H from 1:45 here. But im not sure maybe it could