I'm type 2diabetic, I'm not on any prescription medication I'm diet controld, I take ALA every day along with Benfotiamin and I'm feeling great, plenty of vegetables ,almond milk, whole meal brown bread, I stay away from sugar and fried foods and a low consumption of meat, that's the way to go 🚶♀️ 💯🇬🇧
If you have insulin sensitive and pulmonary hypertension you should definitely investigate Alpha Lipoic Acid. I was stunned with how well it worked for me. However, do your research as you should with any supplement, but for me it was miraculous
I am surprised there is no mention of peripheral neuropathy. I have been taking this for years now for my idiopathic neuropathy along with L-Carnitine. I cant afford to take as much as I would like but it does help whereas nothing else has. I can tell the difference if I ever run out. I pay more for the R-lipoic stabilized version.
I believe it's also useful in case of Bell's palsy. I have given it to 2 persons with this conditions. Both reported fast improvement after taking ALA in the 50-50 form. Plus also they complemented with Lions mane.
I have been taking 600mg of ALA together with Acetyl L-carnitine for about 1 month now as part of supplements I hope will help reverse the Graves disease diagnosis I got in July this year. Glad to know I will be getting all these other benefits. Very informative presentation so definitely subscribing.
R-Lipoic Acid increases acetylcholine production by activation of choline acetyltransferase and increases glucose uptake. This process supplies more Acetyl-CoA for the production of acetylcholine. The only other things you need to make acetylcholine are choline molecules in your brain by using either CDP-Choline or Alpha GPC along with Vitamins B1 & B5. I do NOT recommend lecithin because you do not know how much choline you'll get from it or whether it will even cross the blood-brain barrier. Better to use the above.
Alpha Lipoic Acid is going to mess with your thyroid meds. So if you use it you'll need to keep an eye on your numbers. And increase your Levothyroxine enough to feel 'normal' again.
ALA also works as a dual electron donor and acceptor. As an acceptor it can convert reduced NADh to NAD+ which is smarter than using faddish NAD precursors.
David, thanks so much for the enormous amount of informative content you share. particularly on ADHD and nootropics. For many years I and health professionals failed to spot the inattentive-ADD /ADHD in me. I could not fathom why I was never able to rest or sleep properly. I had misdiagnosed the restlessness as GAD- though I do suffer with anxiety too. The ADHD discovery may now help me to have a real chance at life!
Peter, I was not diagnosed Adult ADD until much later in life. I wonder what my life and career would have been like if I knew this when I was in my early 20's.
Thank you for this video. I have a couple of questions. Question 1: I see some brands offering 600mg of ALA. Assuming it's a 50/50 blend of R and S, is it worthwhile getting a blend or is it better to stick with just the R form? Question 2: I recently came across DL-ALA, which claims to be more stable. Is this a good option and would this also be a 50/50 blend or something entirely different? I'm hoping to treat Alzheimer's. Thank you.
R-ALA has been shown to be up to 12 times more effective than S-ALA which is good enough for me. It has the most research backing its use as well. Best to get a patented form or R-Lipoic Acid like that found in Performance Lab Energy: pulse.ly/h4yn8mjwqr
For me works well S form than the active form R. I feel agitated with R form ,it lowers my blood sugar and i feel bad after taking it for few days. My experience:) Thanks!
@@NootropicsExpert Thank you for this info, however, I take my RLA with a meal. I will definitely start taking again on an empty stomach, which I did at first. Then a vid I recently watched said to take RLA with Selenium and food. I have to say I have been quite agitated and annoyed, as well. Extremely grateful to you!
Steve, not specifically for bone health because this channel is about brain health and cognition. But I do talk about Vitamin K2 for its nootropic benefits in this video: pulse.ly/5tud7jik8k
Thank you for your imformation, i am taking Alpha Lipoic Acid, i feel a diference in my brains, a good antioxidant, Thank God for it, i believe Hé send His Ángeland show me this great supplement ALA 👍.God Bless you.
I have nerve issues with my knees and just started taking the R version of ALA. I found one that is certified by the NFS/ANSI 173 if that means anything. I know it may take a while to work.
Performance Lab Energy uses a patented form of natural R-Lipoic Acid: pulse.ly/8dzyy6oa8d. It provides a nice, smooth, clean boost in energy. Or a standalone product I recommend is: pulse.ly/3du4wbpuna. (Amazon)
Janet, you get an effective dose of R-Lipoic Acid in this supplement: pulse.ly/gazp7pkkd6. which is my favorite form and supplement in this category. It works!
David, you say that the "R" form is natural, could you tell me it is plant or animal-based? And if from animal, what types of animals and what part of the animal is it made from? Thank you.
ALA is unique among other antioxidants because it is both water- and fat-soluble. So, to get its full benefit it needs to be taken with a healthy oil or food containing healthy fat.
I just bought a bottle of Alfa lipoic acid with Acetil L carnetine don't know if it's good mix looking for something that works in my neuropathy on bottom of my feet
Head First 2nd Edition is available in the EU and worldwide. Try Amazon first. But it may take a couple of weeks to get back on shelves everywhere is what I've been told by the publisher.
BB. the links to my free book as well the link for Head First work for me. Maybe there is something in your browser settings that is blocking it. I test everyone of these links before publishing a video. Here is a link to my calendar if you'd like a personal consultation: pulse.ly/459ztz2ur2
Frank, if you use R-Lipoic Acid which is the natural form of this antioxidant found in your body you can use the recommended dosage daily for life if it helps you.
Hello thank you for your much valued videos. Just to check my understanding, I have a question. 11.20 you say, ‘performance lab uses pure RLA, 150mg’. At 13.54 you say, the sodium salt version is more easily absorbed than the natural form. And is contained in performance lab? I need to check cos as you say this video is an update from several years ago and the science may have changed. Thanks from Kay
Kay, the science for this remains the same. Our body using the form R-LA and not the synthetic S-LA. The Performance Lab Energy supplement uses a patented from of R-LA called Microencapsulated Bio-Enhanced® R-Lipoic Acid
Some more recent research shows ALA can be effective for symptoms of dementia. But more needs to be done to verify these findings. But if I was suffering with dementia I'd be using every thing I could think of to deal with it including ALA.
Michael, according to recent studies the L-Carnitine in red meat is converted by a specific bacteria in your gut to produce TMAO. Which is what causes the damage to DNA. But not sure why dietary fats make you dizzy. Could be something to do with your microbiome.
@@NootropicsExpert sir why every food and all supplements n medications cause me a nerve pain specially at one side of the body even face , inside left side tongue , left eyes, left abdomen, left side leg , hand . No doctors diagnosed me this one . Hope you are expert in this field , know better in this. My life is living hell, no hope 🙏 Even there is a kind demylination in the every corner of the body .
Michael, I am not a doctor and haven't even played on on TV. So what you are dealing with is beyond even my 10,000+ hours of research. I suggest searching for a naturopath near you and ask them if they can treat what you are dealing with before making an appointment.
Why has it taken sooooo long to get the ALA message out to the public ? I was treated for cancer with IV ALA two plus years ago. No cancer now. Medical mafia tried to run doc out of business.
Ever since I started taking ALA 2 weeks ago, i've been severly constipated, do you happen to know why, and is anyone else reporting this too? (it's pretty concerning because ALA really DOES help my neuropathy in my feet, so i'd hate to stop using it)
Ian, let us know how it goes. Because I do have a protocol for Long-COVID which has worked for a lot of people. I haven't written an article or done a video yet so would need to share it during a consultation.
@@NootropicsExpert Feel good today, so its taken only 6 days to get better. The ALA gave me a short fever each time I took it in the first 3 days, which I think were good fevers helping me get better faster. I like your videos, and I also taking blackseed oil.
From the research I've seen so far most eventually get their sense of smell back. But it takes time. I am not aware of a particular supplement that will speed this healing process.
Tracy, it seems that a couple of companies have come out using the same patented form of R-Lipoic Acid I talk about in this video. But so far none of the ones I have found are "pure". They contain "other ingredients" like magnesium stearate and silicon dioxide. And Performance Lab Energy does not.
I'm type 2diabetic, I'm not on any prescription medication I'm diet controld, I take ALA every day along with Benfotiamin and I'm feeling great, plenty of vegetables ,almond milk, whole meal brown bread, I stay away from sugar and fried foods and a low consumption of meat, that's the way to go 🚶♀️ 💯🇬🇧
Thanks Maggie.
Lipoic acid from 600mg to900mg ,benfothiamine, l carnosine vanadium and chromium.
I want some Oreo cookies but I’m T2 as well. I use ALA and metformin along with exercise. I just have a hard time with sweets.
If you have insulin sensitive and pulmonary hypertension you should definitely investigate Alpha Lipoic Acid. I was stunned with how well it worked for me. However, do your research as you should with any supplement, but for me it was miraculous
I am surprised there is no mention of peripheral neuropathy. I have been taking this for years now for my idiopathic neuropathy along with L-Carnitine. I cant afford to take as much as I would like but it does help whereas nothing else has. I can tell the difference if I ever run out. I pay more for the R-lipoic stabilized version.
Cindy, it is not mentioned because this channel is about 'nootropic' supplements. In other words supplements that help the human brain.
Thanks again.
I alternate between Resveratrol and ALA. Zero side-effects between either.
I believe it's also useful in case of Bell's palsy. I have given it to 2 persons with this conditions. Both reported fast improvement after taking ALA in the 50-50 form. Plus also they complemented with Lions mane.
Thanks for the report Rafael. Much appreciated!
I used to take this.
Now that I know it's nootropic,I'll definitely buy it again.
I have been taking 600mg of ALA together with Acetyl L-carnitine for about 1 month now as part of supplements I hope will help reverse the Graves disease diagnosis I got in July this year. Glad to know I will be getting all these other benefits. Very informative presentation so definitely subscribing.
Thank you Anne!
Thanks a lot for the High Quality Content.
Thank you for watching Domenik.
Another excellent & very informative video, thank you David!
Thank you Rick! Much appreciated.
Thanks for the Performance Lab ENERGY Recommendation 👍 & Another Very Informative Video 💯
Thanks TC
Very good antioxidant!
Excellent, THANK You 😊👍
You are very welcome! Thanks.
Thank you for the updated review of this very important supplement, much appreciated!
Thanks!
Should we also take sunflower lecithin in order to provide us with acetyl choline?
R-Lipoic Acid increases acetylcholine production by activation of choline acetyltransferase and increases glucose uptake. This process supplies more Acetyl-CoA for the production of acetylcholine.
The only other things you need to make acetylcholine are choline molecules in your brain by using either CDP-Choline or Alpha GPC along with Vitamins B1 & B5.
I do NOT recommend lecithin because you do not know how much choline you'll get from it or whether it will even cross the blood-brain barrier. Better to use the above.
Thank you. It's very helpful information.
Great video with a clear and to-the-point explanation👌!
Thanks Mark!
I'm type 2 diabetic and I take Levothyroxine, & Metformin; should I take Alpha Lapoic Acid?
Alpha Lipoic Acid is going to mess with your thyroid meds. So if you use it you'll need to keep an eye on your numbers. And increase your Levothyroxine enough to feel 'normal' again.
Thank you!!!!!! I have been using ALA,for about 5months now for Neurology problem. Am I doing the right thing??
Gina, you sure are and you'll have even more success if you used the natural form R-Lipoic Acid.
Hi there! Thank you for the update! Love your work. Will you make a video about hydrogen water?
Lily, probably not unless it has some spectacular nootropic value and a bunch of clinical studies backing its use as a nootropic.
I started getting muscle cramps when I took alpha lipoic acid. When I stopped taking it the cramps disappeared. Any suggestions or insights?
Reduce your dose or try the natural form R-Lipoic Acid instead.
So don’t take it before bed?
ALA also works as a dual electron donor and acceptor.
As an acceptor it can convert reduced NADh to NAD+ which is smarter than using faddish NAD precursors.
David, thanks so much for the enormous amount of informative content you share. particularly on ADHD and nootropics.
For many years I and health professionals failed to spot the inattentive-ADD /ADHD in me. I could not fathom why I was never able to rest or sleep properly.
I had misdiagnosed the restlessness as GAD- though I do suffer with anxiety too. The ADHD discovery may now help me to have a real chance at life!
Peter, I was not diagnosed Adult ADD until much later in life. I wonder what my life and career would have been like if I knew this when I was in my early 20's.
Thank you for this video. I have a couple of questions. Question 1: I see some brands offering 600mg of ALA. Assuming it's a 50/50 blend of R and S, is it worthwhile getting a blend or is it better to stick with just the R form? Question 2: I recently came across DL-ALA, which claims to be more stable. Is this a good option and would this also be a 50/50 blend or something entirely different? I'm hoping to treat Alzheimer's. Thank you.
R-ALA has been shown to be up to 12 times more effective than S-ALA which is good enough for me. It has the most research backing its use as well.
Best to get a patented form or R-Lipoic Acid like that found in Performance Lab Energy: pulse.ly/h4yn8mjwqr
Awesome ! Thank you very much !
Awesome! Thank you!
Thank you so much!
Welcome!
For me works well S form than the active form R. I feel agitated with R form ,it lowers my blood sugar and i feel bad after taking it for few days. My experience:) Thanks!
Hamid, whatever works is the right supplement for you.
@@NootropicsExpert Thank you for this info, however, I take my RLA with a meal. I will definitely start taking again on an empty stomach, which I did at first. Then a vid I recently watched said to take RLA with Selenium and food. I have to say I have been quite agitated and annoyed, as well. Extremely grateful to you!
Thanks Juli.
David, I really enjoy your videos. Have you done one on Vitamin K2 Mk7 for calcium redistribution for bone health and decalcification of arteries?
Steve, not specifically for bone health because this channel is about brain health and cognition. But I do talk about Vitamin K2 for its nootropic benefits in this video: pulse.ly/5tud7jik8k
Thank you for your imformation, i am taking Alpha Lipoic Acid, i feel a diference in my brains, a good antioxidant, Thank God for it, i believe Hé send His Ángeland show me this great supplement ALA 👍.God Bless you.
Thanks Janet!
Thank you!🙏🏻
Welcome!
I have nerve issues with my knees and just started taking the R version of ALA. I found one that is certified by the NFS/ANSI 173 if that means anything. I know it may take a while to work.
Great video brotha, is there a brand you recommend? thank you
Performance Lab Energy uses a patented form of natural R-Lipoic Acid: pulse.ly/8dzyy6oa8d. It provides a nice, smooth, clean boost in energy.
Or a standalone product I recommend is: pulse.ly/3du4wbpuna. (Amazon)
I buy it ALA from Swanson but i would like to buy from you , do you have a site?? thank you.
Janet, you get an effective dose of R-Lipoic Acid in this supplement: pulse.ly/gazp7pkkd6. which is my favorite form and supplement in this category. It works!
David, you say that the "R" form is natural, could you tell me it is plant or animal-based? And if from animal, what types of animals and what part of the animal is it made from? Thank you.
Mika, R-Lipoic Acid is naturally produced in your body.
Great video.
🙂
My ALA is from herbs of gold and the instructions is take it with food, should I?
ALA is unique among other antioxidants because it is both water- and fat-soluble. So, to get its full benefit it needs to be taken with a healthy oil or food containing healthy fat.
Thank you so much for all you do, David! Wonderful information.
Much appreciated Tom. Thanks!
Thank you! Really appreciate your videos. They're filled with much good information!
Much appreciated. Thanks.!
Very helpful.
Much appreciated. Thanks.
I take R-lipoic acid any difference?
R-Lipoic Acid as I mentioned in the video is the natural form of Alpha Lipoic Acid that your body and brain uses.
I just bought a bottle of Alfa lipoic acid with Acetil L carnetine don't know if it's good mix looking for something that works in my neuropathy on bottom of my feet
That combination is a good one for increasing energy.
Does ALA increases or decreases acetylcholine?
Increases acetylcholine synthesis.
Awesome background!
Thanks! That was my wife's idea so I'll pass it along to her.
I couldn't find the supplement on the website you linked
Sara, the link just under the video takes you to Performance Lab Energy which contains patented version of the R-LA form of Alpha Lipoic Acid.
5200 mg per day based on 240 mg per pill, I would be taking 21 pills per day. Is that 5200 mg per day correct for anti-oxidant treatment correct?
Alpha-Lipoic Acid dosing for antioxidant benefits is 50 - 100 mg per day.
@@NootropicsExpert Thank you I mis-heard you.
Hi your book head first is not available in EU ? could you suggest where to buy it, thanks
Head First 2nd Edition is available in the EU and worldwide. Try Amazon first. But it may take a couple of weeks to get back on shelves everywhere is what I've been told by the publisher.
Hi David the link to your book is not active, also what's the best way to book a 1 on 1?
Thanks mate
BB. the links to my free book as well the link for Head First work for me. Maybe there is something in your browser settings that is blocking it. I test everyone of these links before publishing a video.
Here is a link to my calendar if you'd like a personal consultation: pulse.ly/459ztz2ur2
clear lactate synergistically with methylene blue
How long do I drink this alpha lipoic acid..
For as long as you need it.
Why does nobody ever mention how long to take it for. Is it 1 month 6 months or for life?
Frank, if you use R-Lipoic Acid which is the natural form of this antioxidant found in your body you can use the recommended dosage daily for life if it helps you.
Can it be taken with Huperzine
Yes it can.
Hello thank you for your much valued videos. Just to check my understanding, I have a question. 11.20 you say, ‘performance lab uses pure RLA, 150mg’. At 13.54 you say, the sodium salt version is more easily absorbed than the natural form. And is contained in performance lab? I need to check cos as you say this video is an update from several years ago and the science may have changed. Thanks from Kay
Kay, the science for this remains the same. Our body using the form R-LA and not the synthetic S-LA. The Performance Lab Energy supplement uses a patented from of R-LA called Microencapsulated Bio-Enhanced®
R-Lipoic Acid
Will this help for white matter disease?
Debbie, see the section of my video on brain aging called "Vascular Dementia" at 23:37 in this video pulse.ly/yynq3yeztp
What about other types of dementia?
Some more recent research shows ALA can be effective for symptoms of dementia. But more needs to be done to verify these findings.
But if I was suffering with dementia I'd be using every thing I could think of to deal with it including ALA.
Sir , do you know why carbs n some red meat daily for year damaged my mitochondria! Now if I eat dietary fats I get dizzy ! Why ?
Michael, according to recent studies the L-Carnitine in red meat is converted by a specific bacteria in your gut to produce TMAO. Which is what causes the damage to DNA.
But not sure why dietary fats make you dizzy. Could be something to do with your microbiome.
@@NootropicsExpert sir why every food and all supplements n medications cause me a nerve pain specially at one side of the body even face , inside left side tongue , left eyes, left abdomen, left side leg , hand .
No doctors diagnosed me this one . Hope you are expert in this field , know better in this.
My life is living hell, no hope 🙏
Even there is a kind demylination in the every corner of the body .
@@NootropicsExpert sir, do you help me on this , if I consult you ?
Michael, I am not a doctor and haven't even played on on TV. So what you are dealing with is beyond even my 10,000+ hours of research.
I suggest searching for a naturopath near you and ask them if they can treat what you are dealing with before making an appointment.
Why has it taken sooooo long to get the ALA message out to the public ? I was treated for cancer with IV ALA two plus years ago. No cancer now. Medical mafia tried to run doc out of business.
Steve, thanks very much for your input.
What dose injection
I am only familiar with dosages in capsule form. Not for injections. Maybe someone else has experience with this method.
Ever since I started taking ALA 2 weeks ago, i've been severly constipated, do you happen to know why, and is anyone else reporting this too? (it's pretty concerning because ALA really DOES help my neuropathy in my feet, so i'd hate to stop using it)
Corky, are you on meds for thyroid or diabetes?
👍👍👍
On the treadmill it makes me heat-up more. Anyhow, I now got COVID so I am taking a few ALA tablets to help me recover.
Ian, let us know how it goes. Because I do have a protocol for Long-COVID which has worked for a lot of people. I haven't written an article or done a video yet so would need to share it during a consultation.
@@NootropicsExpert Feel good today, so its taken only 6 days to get better. The ALA gave me a short fever each time I took it in the first 3 days, which I think were good fevers helping me get better faster.
I like your videos, and I also taking blackseed oil.
From the research I've seen so far most eventually get their sense of smell back. But it takes time. I am not aware of a particular supplement that will speed this healing process.
Have you every checked out Life Extensions R-Alpha Lopic Acid?
Tracy, it seems that a couple of companies have come out using the same patented form of R-Lipoic Acid I talk about in this video. But so far none of the ones I have found are "pure". They contain "other ingredients" like magnesium stearate and silicon dioxide. And Performance Lab Energy does not.
❤
FIRST!
I find it seems help with Parkinson's movement
I think you will find it even more effective if you combine it with Acetyl L-Carnitine (ALCAR).