Plastic found in our Arteries, but it’s Not all Bad News [Study 283]
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- Опубліковано 14 кві 2024
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References (Copy & paste DOI into Search Engine)
[1] [Study 283] doi:10.1056/NEJMoa2309822
[2] my.clevelandclinic.org/health...
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#heartdiseaseawereness #cardiovasculardisease #plasticfree
![Microplastic Dangers? [How to Avoid Microplastics] - 2024](http://i.ytimg.com/vi/1qrf3b5RcUo/mqdefault.jpg)
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Hey Nic,
Thank you for all the work you have done. Your content is gold.
It might be interesting to discover the half-life of these microplastics and / or studies related to clearing them.
Other than plaque, where else do they reside in the body? Or do they remain in our blood?
PFOA, PFOS, and PFHS have half-lives over 7 years, reportedly.
For my part I donate blood as often as often as I am able.
Thanks
What if inflammation is caused partially by the plastics
@@franzb69 🔥
My client the Michelin Man has asked me to assure you he consists entirely of rubber, contains absolutely no plastic, and deeply resents this aspersion cast upon his character.
The rub is from the pickpocket sliding your goods away
Well, as well he should!
He's synthetic rubber and he knows it!
@@michelem226 No relation?
Down with plastics, up with glass. I love glass.
I prefer glass, too! I know it costs less to transport plastic, but I think it would be nice to go back to the days when we could be “reimbursed” for recycling glass - it would encourage the use of glass & IMHO might increase other types of recycling.
Filtered water in stainless steel bottles, no non-stick cookware, no plastic wrapped frozen dinners, no disposable plastic bowls, dishes, forks, spoons and knives. This cuts back at least some of the amounts of plastic ingested. But then there is the forever chemicals hanging around... wild goose chase.
Great comment! And yes.. definitely feels like we’re in a “Twilight Zone” version of a “Alice in Wonderland”….
Nice quote. "Take the data as it is, without over-extrapolating". Sounds like a key piece of reliable science
They should of also checking testerone levels in that study.
“Big water bottle” is always watching you.
Making sure I don’t diss them
shouldn't it be "big bottled water"?
Is there just a big ass sentient watter bottle out there?
@@BorisK296Big Water Bottle does have that menacing vibe. Big Bottled Water just makes me want to pee.
@@bearcubdaycare 😂exactly
My father worked for a glass company. The day my mother set our table with new modern plastic plates, he fell to his knees in tears, jumped up and tossed the plates out the front door like frisbees.
Laboratory studies have shown that microplastics and nanoplastics can cause various adverse effects in cells and animals, including inflammation, oxidative stress, and genotoxicity. These effects are often related to the plastics' size, shape, and chemical composition.
Research by Prata et al. (2020) demonstrated that inhalation of microplastics could lead to inflammatory responses and potential respiratory issues in mammalian models.
This is absolutely incredibly creepy, I'm sorry, but I don't want plastic in my arteries, for any reason, our world is becoming so polluted it's very sad
This carotid endarterectomy was done on patients who actually needed one, because they are occluded or near-occluded and symptomatic.
I'm surprised they found people with no microplastics in their blood.
Perhaps some people have a better ability to break down plastics or remove it from the body.
Perhaps their gut biome is able to deal with the microplastics?😊
Plasma donation helps
Just no plastic in their plaque, right?
My mother had that surgery you're talking about in the beginning.
At first I thought it was cool and wondered if they could do that in every blocked blood vessel but then I realized all the complications with the scar tissue etc.
A few years later she had a myocardial infarction (I think) and I've always wondered if it could've been because of the surgey?
Non-native speaker here so please excuse any spelling mistakes.
Your mother is braver than I am. I'm sorry she had a heart attack, however. Seems unlikely to be related, because keep in mind that plaque build up doesn't occur in only one place. Your English is great!
@@Physionic Thank you for putting those thoughts to rest. 🙏
I have to say that I love watching your videos.
You're my definition of a wholesome role model and I hope your channel blows up.
You've helped me with a lot of questions I had and I'm very grateful.
Out of an abundance of caution, I stopped drinking water bottled in plastic five years ago. I cringe when I see people refilling single-use plastic water bottles…especially when they add flavoring or citrus which may erode the plastic.
I've refused to use those for years due to how horrible they are environmentally
@@dannyspitzer1267i did the same and added citrus etc.... We are in a terrible pickle with how we have assaulted our own biomes and that of earth with petrol derivitives.
Those bottles are PET. PVC and PE make me think of old deteriorating water mains and distribution lines as the cause. Some plastic water mains are 50-60 years old and of inferior quality and have been high pressure flushed, chlorinated, mechanically cleaned etc. Those pipes are fine mechanically for another 50 years but their interior surface might be shedding microplastics into the water.
@@jmc0369boy are you confused. Just keep believing the lies spoon fed to you by the media.
You do realize that all water passes through plastic pipes to get to your house.
On a related subject - persistent chemicals, I learned a while back that routine longer term blood donations can greatly reduce these chemicals in the body which almost everyone has (fire retardants being common). I switched from whole blood donations to platelet and plasma donations about 2 years ago. The greatly increased donation frequency and has an indirect side effect of allowing me to turn over plasma volume many times (about 8 plasma volumes so far), so guessing this might also have an effect on micro plastic for anyone with a load. But I am not a user of plastic bottles and am on a home well so guessing I am low.
Plastic bottles aren’t PVC or PE. Water pipes are often PE and sometimes PVC. Early plastic water mains and distribution pipes are 50-60 years old now and they used lesser quality plastic and have been flushed, mechanically cleaned and subjected to chlorinated water all this time. Mechanically they are fine for another 50 years but the surface could be deteriorating and shedding platics into the drinking water.
Since 40% don’t have it that makes me think those 40% don’t have old plastic water mains or distribution pipes and the other 60% do to some extent.
I hope there will be studies about the material dynamics of microplastics and plaque: e.g. does plaque passively absorb microplastics, or are microplastics causative in plaque formation
My feeling is that those plastics that are most likely to degrade probably contribute the most to our micro plastic load. I gave up plastic cups for this reason. I do use a plastic sports bottle, but change the water frequently and don't drink the last bit in the bottom. I have experienced the taste of plastic in water that sits in the bottle and the last bit. I use glass jars for anything that has to sit or stored in the refrigerator.
I used to have a glass bottle to keep water in the fridge, until I found a piece of glass sitting on the bottom. It had broken off the bottle, and was lying there invisibly because it was the same refractive index as water. I decided then that maybe microplastics wasn't so bad.
What about all the microglass tearing up our urethras?
What if.... a lining of microplastics decreased leaky gut in some people?
There is a video on youtube with a php degree who specialized in effects of plastic in organic matter. She said that it takes the body about 6 days to get rid of plastic that's been consumed through food and liquids.
Would you have the title of the video, please?
@@r.guerreiro140 i checked my yt history but it's not there
@@r.guerreiro140 I think her name was Shanna Swan
100 percent science fiction fear porn nonsense.
I wonder how long if you’ve been exposed to/ consuming plastics for decades…?
The PE and PVC content suggest to me it’s from piped water. If it was mainly from water bottles or microplastics from clothes drying it would be mainly PET or polyester respectively. Many food containers are PP (lunch boxes etc and plastics meant to be microwaved) or PE (cling films and low temperature food containers); a few PS (e.g. Coffee cups). The most abused plastics here are made of PP; reused; eaten directly out if them etc. That’s why I expect these are old deteriorating PE pipes.
So banning or avoiding plastics in drinking water and food containers/wrap would be the most impactful changes to make?
I know it would be practically impossible to replace all residential/drinking water PVC piping, but it could at least be phased out in new construction and repairs.
Physionic, a channel about English idioms with occasional diversions into insights on health.
And there it is. He's finally talking about. Now I'm very curious what he has to say. The harder stuff is always the most difficult to talk about because it's terrifying implications.
My uncle had this surgery after a series of fainting spells which resulted in pretty serious head injury. He was indeed as good as new. He did have a heart attack recently though. Roughly 8 years later. It has been a few months and he is recovering.
Always important to distinguish between associative studies and causative ones!!!
What about the endocrine disruption of said plastics etc? Have you done a video on this?
I think the real danger is the continual leaching of hormone-like chemicals.
Estrogen hell. Forever. 💩
How about doing a breakdown of the twin study and telomere length. Which is a marker for longer life expectancy.
Go to the grocery store and try to buy something that isn't packaged in plastic. Is bottled water worse than other things? Is the skin a good barrier to keep out PE and PVC? My guess would be that synthetic clothing wouldn't be the main source, food packaging would. The microplastics were found inside macrophages. That means the immune system considered them antigens. But what are these macrophages doing in the plaques anyway? Did they get trapped inside? Or did the plaques look like infection sites? Considering where they were taken from, it would be good to know why the plaque is building up there.
Glottochronology 101: "Early recorded use refers to a type of 16th century horse race where everyone had to try to follow the erratic course of the lead horse, like wild geese have to follow their leader in formation."
.....like following UA-cam gurus as they change course? Cool.
@@laurahiggins8594 *LOL* Touche!
Our prior on plastics causing inflammation should be pretty high.
Old cancer studies involved sticking physical obstructions into tissue and waiting for the inflammation and disrupted cellular communication to kick in.
Additionally, microplastics likely interfere with our ability to resolve inflammation.
I imagine that chasing a wild goose would become a bit of a wild goose chase. But apparently that's not the etymology, which includes a use by Shakespeare, and prior to that, horse racing.
Chasing goose seems like a wild and dangerous sport to me 😂
That’s a surgery for people with carotid artery blockages. My mother had it over 20 years ago. People opted for the surgery because they didn’t want strokes or trans ischemic attacks.
Really interesting! Many thanks for sharing.
The fact there are microplastics in our arteries should ring the bell about public plastic regulation. I really don't care if it seems harmless, however I don't think any sane human claim that it is and will certainly be harmless in the future.
Great stuff as usual . Plastic is the new lead (Pb). !
love your content, i dont miss a single video
Thanks!
same for me!
6:19 plaque is filled with “foam cells” which as former macrophages. It could be that as macrophages pick up plastic, the will accumulate in tissues where macrophages accumulate (in the endothelial foam cells).
I've decided to run all my blood through an R.O. filter just to be safe. I 3D printed one out of plastic.
Excellent... that will definitely work.
Brilliant!!
I would be very interested in knowing why 40 percent in that study had little plastics in their body.
Gut bugs that broke down the plastic? Good city water? Well/cistern water?
It's only guesses until someone asks them.
Yeah, that INCREDIBLY major disparity from everything I've heard, so far, really concerns me most of all with this - I have yet to hear about ANY study where biologically-lodged microplastics were not _ubiquitous_ - !!!
So - wtf is up, here? What's the truth?? Did THIS study somehow not measure perhaps _finer_ microplastic content presence? _Lower_ microplastics levels presence? _NON-cardiovascular_ tissue microplastics presence?
I have been drinking my water from plastic bottles for decades and will continue to do so. You can't always be unsettled by everything.
I would put this in the jury as out category because it always is in this kind of situation.
George Davis
Wow, you are really wound up today concerning this subject 😂😂😂
Just wait until Wednesday… :)
Could be BPA or phthalates which leach. Would have been easy to measure.
Why would there be BPA and phtalates in PE and hard PVC? If water bottles etc were the main contributor it would be PET.
I bought a glass jar blender, cottons bed sheets and blanket, a cotton mop, silicone freezing bag, silicone dish cleaning pads, a steel frying pan instead of my non stick pan, I dished my rice cooker, my frying pan, my plastic food processors my bed sheet and blanket, my plastic container and food processor, I will buy organic wood toothbrushes this week
I have seen suggestions that increased plastic burden is associated with higher consumption of highly processed foods. Could this be a missed factor?
"Aye there's the rub," ......Hamlet, BTW! One of the MOST frequently quoted plays for precious little sobriquets! Alas poor (you insert the name as needed,).......I knew him well!
Yorick!
@@azok5963 I knew it was Yorick,.....i was indicating how many times in our lives have we "petrsonallY" used said phrase for personal assignmenty? Eg....an acquaintance or friend dies and you may..............ohhh forget about it! I really cannot believe how stupid some people are ! Judas Priest!
Let me guess: those without microplastics hardly eat fish.
This scares the hell out of me
Maybe with all the plastics and preservatives we will live forever
Micheline Man aka Bibendum 😉Very informative video as usual! Thanks!
Could you do a video talking about Rhodiola Rosea ? Thanks for the great videos ❤
I certainly can
I remember seeing a study (though painfully I cannot find it) pointing out that people who lived before plastics were used ubiquitously also still had the plastics in their arteries. Thus supporting the idea that it isn't from plastic usage.
but im sure their levels were also lower than what we found commonly in the body of modern human?
@@mrgrumpycat9049 Possibly, but it really doesn't matter. If you found any at all, then you know there is another mechanism than ingesting modern plastics.
@@InfiniteQuest86 I'm pretty sure back then, the exposure of microplastics came from the industrial waste products and air pollutions?
Did the study take into account other lifestyle effects. I believe it is common to find correlations between income and how much one eats packaged foods. Is the plastic a correlation or causation of inflammation?
WRT your "H311 NO!" it is indeed ALWAYS best to explore non-invasive solutions FIRST; that being said, if the plaque is cutting off the blood supply to the brain, the invasive technique may have been warranted...
I wonder if people with some degree of leaky gut syndrome tend to accumulate more microplastics in their bodies(and hence their arteries) simply because more plastic is infiltrating their bloodstream from their digestive system through what they eat and drink(as well as what they inhale since much of that microplastic winds up being ingested as well)?
“Thus conscience makes cowards of us all”
maybe smoking cigarette or others bad habit could increase the amount of plastic in the body, or decrease the body capacity to expell them?
Don't worry guys it's HDL-plastic it's actually cardio protective.
Ah - Great point! I guess we can all now rest easy... 👍
The inflammatory response is how the body is supposed to respond to foreign objects in places where they don't belong.
That doesn't explain inflammation from hitting your elbow on something.
At a molecular level, seems unfeasible that such and inert compound as poliethylene can have any interaction with our metabolism are all
@@VegetaPrinceOfSaiyanscoordination problem.
Who doesn't want a free Carotid Artery deplasticification?
This makes me think of one of my favorite songs to sing and play on the guitar, Fake Plastic Trees by Radiohead 🙂 💚
60%? What was the percentage of obese people?
Check out the baseline data shown
Most of my salad eating comes from the grocery store in meal-sized plastic bowls with a plastic fork. I currently throw out the plastic fork, but now I'm wondering about the container it comes in. I don't want to stop those salads because they are so convenient.
From my understanding plastics bleed in to liquids easier than solids. The dressing would probably be the most “contaminated” while the salad leafs and all could be negligible
Yes, I _imagine_ that the more acidic the substance (mainly liquids), like vinegar/many dressings, are worse (but definitely don't take that as necessarily factual; I don't know that). I might also wonder if oils absorb/dissolve microplastics, oil being oleophillic itself, and plastic being petrochemical in nature.
But these ARE things I really, _really_ hope we'll all be learning about, as the general public, before too long... It's just too ubiquitously important to public health, going forward, for us to not gain some kind of general working knowledge about it.
@@justinklenk that would make sense.
My ultimate hope is all the preservatives and plastics have a benefits of prolonging our lives indefinitely 🤞
@@bigthunder7002
One can dream... Lol
@@justinklenk Thanks for all the great replies, which provide some interesting things to think about.
Perhaps with a little more effort, I could buy the salad dressing that I most commonly use in glass bottles and then discard the fork, washing the leaves before transferring them into a bowl.
This is all precautionary, but I didn't transition away from over-processed foods just to start accumulating plastics in my arteries.
I have had two carotid endarterectomy’s. Piece of cake!
When petrochemicals (including plastics) are burned in people's yards, I have inflammation from breathing the particles in the smoke. In my experience, inhalation of plastics causes more concern than consumption of nanoplastics.
Hell no! 😂. Totally agree. Those volunteers are super brave… or, incredibly gullible.
That's a big HELL NO! From me as well
Maybes a follow up video on how to counteract this (if possible)? Sauna, exercise, nattokinase...
A guy that lived with me for a while had this done. How is it done? Because they'd have to get under the endothelial layer, wouldn't they? I don't see how you can just pull out some plaque unless you do some major damage to the artery.
If we reverse the cause then maybe inflammation made it easier for plastic to get stuck, like how LDL cause more problems in the presence of high blood pressure.
hey can you analyse the research that says that consuming dihydrogen monoxide causes increased urination?
Totally a myth. It’s a conspiracy. 😜
That's because it contains lots of vitamin P.
That's what the secretive propaganda machine wants us all to believe, brother! Trust me.
Just come to my Flat Earth Society meeting tonight, and I'll explain like, _everything,_ man... 👍
I'd be interested in correlations between plastic consumption and sugar consumption. Big sugar trying to find a scapegoat.
Thank you for this great video! I made a video on the exact same paper and came to the same conclusions. A fantastic paper that is very thought-provoking, but in no way can we prove causality from it. Should we pay attention to it and potentially change our patterns to lessen our plastic burden? Absolutely. Does it prove that micro plastics cause heart disease? Absolutely not. Thanks for the nuance!
Leaky gut maybe causes both?
The plastic in our arteries is not yet radioactive! Good news abound friends!
😂
😂 "Big Water Bottle". I have heard of ''going on a wild goose chase" all my life. Unfortunately, I have been on a few in the true sense of the phrase a few times in my younger more naive times too. 😐 Thanks!
Was there any correlation with diet? Especially people who eat or avoid seafood which is a huge contributor to microplastic intake
Please note that carotid endarterectomy is a proven scientific procedure to help in stoke prevention in patients who have been detected to have more than 70% stenosis or narrowing of the carotid artery. So no vascular surgeons would perform or advice to undergo carotid endarterectomy 🤓 to detect microplastics.
The lack of a health oriented approach is the common factor. People who care vigilantly for their health do not drink from plastic often at all. It is one's approach and philosophy of how best to live life which affects all aspects of our health. Kudos on the "Big Water Bottle" :)
Is there an easier way to test for microplastics, like a blood test? You're not alone in your aversion to having your aorta opened up. If there was a less invasive test, we could hopefully correlate lifestyle or physiology with the presence of microplastics
Did the people who had the worst outcomes also have the most plaque overall? Were there any cases where the outcome did not correlate with total plaque? If plastics were the cause, I would expect people who have lower total plaque but higher plastic percentage to have notably worse outcomes than people with similar plaque levels but lower plastic percentages.
Wondering if sweating (such as in a sauna setting) could be an effective way to excrete these compounds.
The body has a robust lymphatic system to get rid of trash and toxins.
Endartectomies are common place and have been for decades. That is the problem with non physicians talking about medical issues . They have no experience
How did they find patients without mnps?
They didn't specifically look for them
Could the effect of pulling microplastics out of the artery cause more damage and therefore encourage further and increased formation of plaque?
Dude, you are hilarious!
Given how biologically inert plastic is, I would be surprised if it is causing the inflammation.. I always imagined that it would physically block intracellular functionality and fk me up somehow.... Will be looking forward to more research in the space.
(I am at 80% watch time)
Wild geese fly making them impossible to chase, farm geese have one wing clipped, making them dinner.
So when those cells die where do the microplastics go? I read somewhere that the only way to shed microplastics is sweat. Is that true?
And I have to have my carotid plaque removed. Now I'm a bit freaked out about that.
Love your “Big Water Bottle” comment!😆👍
Was the virus that must not be named discussed as a confounding factor?
Isn't also possible explanation of the data that inflamation causes higher retention / impaired disposal of consumed microplastics?
Maybe the macrophages already had plastics when they got stuck in the plaque. Anyway, this won't stop me from enjoying my daily PVC pipe smoothies😅
Life in plastic. It's fantastic.
looks like they could take blood and measure the plastics and cholesterol and come up with a formula to figure out the potential risks of heart failure or strokes.
Is it true that you can remove it with plasma donations?
Could ultra processed food consumption be the connection? UPF is always wrapped in plastic it also is not good for health in other ways. Some people eat much more UPF than others?
Question: does consuming plastic cause plastic in the arterial plaque?
Maybe drinking sodas out of plastic bottles?
It's "Where's the rub?" not "what's the rub?"
I think this study is about as strong of a link as smoking
So, go keto or keto-vore & check out how to clean/clear out your arteries.
Sounds like about the best we can do.