How Some Generic Drugs Could Be Killing Us
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- Опубліковано 22 сер 2024
- Gaps in how the U.S. Food and Drug Administration evaluates the safety of generic drugs allowed cancer-causing impurities to end up in blood pressure pills taken by many Americans.
#BloombergBusinessweek #Storylines #Pharma
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This is not the cost of "cheaper drugs". The cost of drugs in the US is the highest in the world.
This is the cost of for-profit unregulated pharmaceutical production.
CHINA
Have you learn nothign after watching this video. Gotta blame China
Unregulated pharmaceutical production that has infiltrated and contaminated the FDAs regulated pharmaceutical production stock, thus making it toxic for human consumption.
@@Trgn China has got nothing to do with this. The americans ordered cheap harmful drugs for their citizens because they don't care about people.
Yeah I stopped watching right there. In any advanced country you can get the same safe drugs for pennies. 🙄
As a chemist, we have too much faith in the pharmaceutical industry.
Well when you let the dea restrict drug through the war on drugs and then trust these people to supply drugs you allow for problems like this to happen most of the medicine and furthermore allow less people to get the right treatment. They restrict chemicals, and drugs based on there views of politics they don’t do tests properly because they only want 1 company to look over said drugs. So there a major problems with the fda and the big pharma industry
Exactly why we need generic drugs.
If you know anything about chemistry you will know that this was such a school boy mistake. They developed a way cheaper method to synthesize valsartan but forgot the last washing step. Some people might say they did it on purpose to save money. But every undergrad chemistry student would be have been able to spot the mistake in the cheap synthesis causing these problems
What country do you live in, in which chemical synthesis is taught at school whilst a boy?
At best, we did basic titration here.
@@kaydog890 Germany. I had it in my first semester of pharmacy. But I choose to not take chemistry as my primary in high school.
Some people will even have it in high school
no one has actually quantified the amount of NDMA in these mixups to my knowledge and its typically only certain batches.
To me it seems much more likely that because there isnt enough demand to run these chinease/indian super plants around the clock all year long, the plants are constantly switching between different in demand products, either drugs or simple chemical manufacturing when no one is looking. the NDMA that is randomly poping up in every drug now, valsartin -> levothyroxine -> metformin, I believe its solvent that is being left in odd parts of the plant, condensers, rubber parts.
it is industrial greed and globalism that has gotten us here. its not a simple school boy mistake in my opinion.
@@vevenaneathna but in the case of the Valsartans it was a simple mistake. They left out a washing step. Also they used the wrong solvent. If you just draw the ingredients you will see how NDMAs are formed :)
Simple school boy mistake there
@@CaptivaLP idk every 2-3 months my pharmacy gets another recall notice on another random drug due to NDMA. its gotta be something with the plants not specific to a certian drug's synthesis
The fda has had this lack of testing problem for so long that theyre practically a joke at this point.
They've been cronically underfunded and powerless dealing with companies
They need more funding so they can have a bigger scope. Big Businesses lobby against providing them funding so they can avoid scrutiny and maximize profit while minimizing regulations.
A lot of people don't want to increase government funding even when in this case it would be far more beneficial for this country. Also you have both drug companies and the "alternative medication" groups that would lobby against it. Heck there are a lot of stuff in so called health stores that have a lot of false ingredients and people like them benefit from the FDA being underfunded.
Money makes people turn a blind eye
Foreign company: Hey we changed some formula, but it should be ok..
FDA: Cool..
The very fact that lobbying is legal in USA aides this kind of tragedies.
"karen was one of the kindest-"
_didnt expect that one_
If this happened to me someone would finally be forced to say something like: "yeah he was mostly a foul tempered prick and especially so in the mornings, but l guess every human life has an actual innate intrinsic value regardless."
@SofaKingShit that's frickin hilarious
A huge problem is that we have a system that the pharmaceuticals self report to the FDA . The FDA should be doing the testing since most of the R&D is done by University and subsidies anyway.
you would need to tax the rich for this luxury my friend, otherwise it will get worse I'm afraid
You can tax the rich all you want...the rich passes to us i different ways. @josephyoung6749
I was hearing her say MDMA! I was like,
'Whaaaat? A carcinogen? Nooooooo!'.
My father died of a rare cancer at only 53 years old. He'd taken Zantac daily for many years and was consistently exposed to lubricating machine solvents in his work. Both are implicated for the presence of NDMA. The lack of consumer safety is infuriating. And it's heartbreaking to know that others have and will suffer unnecessarily.
Sorry for your loss. This is so sad.
All what is introduced in this thread is to support monopoly about criticising the generic drugs.
The patent is not 10-20 years even treps treaty ask for at least 25 years and us is given even more and sometime double this period by loopholes in their system.
"The quality can suffer sometimes when money is the bottom line" 6:14. I mean this is true, but there is no way this woman would say something like this about brand name drugs like insulin (which is over $600 a month for those without insurance). This is the fault of an inefficient government and greedy corporations, not Americans seeking more affordable drugs because health care costs in America are ridiculous.
Can you imagine if we had taken all that money on the failed war on drugs on drug safety instead.
Or you know, education... health and well being being on the top of the agenda.
profit over someone's life? this is how we know we've failed as humans.
Some people are weird
This is precisely how the Military Industrial Complex works too. Hasn't stopped us from being fascinated by fighter jets , cruise missiles and sniper rifles. Buddha and Gandhi's teachings are wasted on us.
Eh I'm fine with blood money from Lockheed Martin
Covid
Please tell me who to contact. I’ve been on this drug for 16 years and now I’m being seen for possible liver cancer
Should've done research about what you taking man. These Americans don't give a fuck about you
I wish you well Adrianne
Wow Bet you've never ingested anything without researching it and every chemical in it. Our food products, are just as bad as pharmaceuticals on cancer causing additives, colors, BPAs, preservatives etc. Obviously even if they did there research, there was NO information 14 years ago to suggest that this drug caused cancer. So Jeremiah how about a little fucking compassion.
Still many of these drug companies charge prices that cant be explained with the research cost. Just look at the price difference in the us and europe
Most of the research is done or covered by the government anyway. Big pharma just wants that double dip.
Yeah, because the US government gives them the right to do so. Unchecked capitalism is great isn't it?
Its about the market. In the US insurance companies make deals and pay far less than sticker. Also, not all generics for one drug are made by the same company.
@@cancerino666 can you contact me please
So, explained what is probably meant with the EKG pulse:
The EKG pulse is probably a graph of a gas chromatography detector (I am not a chemist but recently spent a night watching videos about gas chromatography so I have some basic knowledge about it).
This method splits a mix of substances by vaporizing the substances and letting them get carried through a long coil of glass tubing inside an oven by an inert gas. Depending on the type of molecule it will take longer or shorter for a given substance to reach the other end where it will end up in some kind of detector.
So, (simplified) if you know how long it will take NDMA to get carried trough the coil you can look at the graph, see that spike, notice that it is at the same time that NDMA would appear and, well, be pretty sure that your sample contains NDMA.
In reality the detector always puts out noise to some degree, so having some small peak somewhere might also be the product of not doing the gas chromatography correctly or having some other issues (-> what they called "ghost peaks")
At which point you do a confirmatory test. If it's random noise, you shouldn't get the same peak. This is besides the fact that all pharmaceutical testing is heavily controlled and a noise peak would be a deviation from the standard test result. This was blatant negligence on the bulk supplier. Novartis managed to identify it even though it wasn't the producer, which speaks to the difference in the standards of testing between the two companies.
Ah. They played the same trick as Boeing did.
"Safety Critical": "False"
Lol there is no such thing as "ghost peaks" on an NMR test. Finding unknown peaks means that there is most certainly some contamination and calling them "ghost peaks" is just lazy chemistry.
To me it sounds more like willfull blindness.
I think the FDA needs to have more funding, and be given more powers. It's entire purpose is to protect Americans from contaminated food and drugs, but clearly by not regularly inspecting generics, they've failed in that duty.
We all know where Bloomberg stands on healthcare costs.
Generic is not problem. The not testing generic drug before approving is.
I hate how they allow so much toxins in our food and drugs and the companies will say, how it’s such a small amount that it’s harmless. Yes maybe taking or eating something once or twice it is. I’ve always thought, what about over a lifetime or over 20 years?
Ok. I will stop buying generic drugs. But can you tell me how I will be able to afford non-generic medicines when the US itself had skyrocketed the prices?
I thought Americans were paying outrageous prices for drugs. Relying on China for drugs is a wrong decision
Just so you know this is a total propaganda piece.
What we learned from the Martin Skreli incident is that drugs are priced at what the execs understand to be the most they can charge without losing too many customers. In this video one of the experts says safety is one of the costs. -And if pills were priced based on cost to produce that would be true. BUT IT'S NOT. They price them based on what they can get. Period. So safety doesn't cost more. Having corporations costs more.
Secondly, they say generics aren't as safe. But that's total bullshit too. Think about it, if it's been on the market long enough for the patent to expire, then it's probably very safe. So the only problem is that producers need to be tested/regulated, like every other industry. How hard do you think it is for the FDA to test a few samples from each major provider? every now and then? Really people we don't EXPECT that of our government? That's fucking pathetic, and the takeaway message shouldn't be that generics are bad, it should be that our government's fucking pathetic, and now that Bloomberg is an untrustworthy source of news.
I really hate your narrative against generics and makes me think this video was sponsored by big pharma. I think this was a case of a few bad apples which should be weeded out by proper testing by the relevant authorities.
As a doctor from a developing country, generics have been a lifesaver for our populations. This kind of fear mongering is dangerous
The problem is no the generic drug, thr problem is where and who manufactured, outsourcing medication and ingredients from certain countries are very worrisome.
In my opinion, Aurobindo is the worst pharmaceutical company. All of the medications I have had from them seem like the dosing is off. If you take a daily pill for whatever reason, then I'd try and steer clear of this generic company.
It is the same idea as having a recall on cars.
They will only give out a recall if the amount of people dying or getting hurt are suing is more than the cost of the recall.
The amount of people dying or getting hurt should be 0.
But it is probably cheaper to keep the people quiet that are dying from these products versus fixing the product from killing people.
F is this world we live in.
I'm extremely suspicious at the fact that Bloomberg is putting out this kind of content considering Mike's history of corruption.
that's why they made sure to say that the cause is "people want cheaper medicine". They are trying to convince the public that prices must remain ridiculously high, otherwise they cant' guarantee our safety
The problem is not the cost to produce the medications (it cost cents to produce hundreds of pills) the problem is the healthcare system in Germany nearly every medication is covert to 100% by all health insurances and we don't have contacted generic medications
Hi! Can you expound in this? I can't understand what you mean.
They stole that womans life !
These drug companies deserve to be dismantled. This is so disgusting.
Replaced with what? How do you convince people to go with tearing down a business millions are dependent on? Many of them are evil in their practice, but you can't just tear it down
@@kevinc9065rely solely on one manufacturing company and ensure quality, purity, and consistency. With too many companies it’s hard to keep track, but simply expanding one company to a larger mass production capability would work far better. The people deserve real drugs, getting bogus drugs from a pharmacy is the biggest slap in the face.
I had a reaction to one medication that caused me to almost stop breathing. I was then given a replacement that was shortly after found to be causing liver damage. How are these things making into the market at all? Since then, I've taken nothing more than Panadol and that, only once a year.
Most drugs have some kind of side effects.
They get allowed when the benefits are thought to outweigh the possible harm
It is not about cheap or expensive drug it is about greed and the bottom line that hurt the consumer regardless whether the drug is cheap or not.
A drug that cost $10 to manufacrure should not cost us $800
It was a global recall and most came from India. How this story can focus on China is just politics to maintain American hegemony
Chinee bat soup generic
@@80sidd 👈👈👈beggar pajeed
thats so badly explained generics costs 20 times less than the original and thats what matters to 99% of people who need it on regular basis and if done as should they are perfectly safe the problem is a bad manufacturing which has nothing to do with its being generics
best comment. generic is not problem. The not testing generic drug before approving is.
This is criminal. Justices must be served
Same thing with Zantac.
Now I know why India became a generics hub, never made a lot of sense.
Well here we come, government generics manufacturer? I mean how else are you going to prevent farma shitting on you?
6:30 Outsourcing is the fault of companies in the US, not whatever poor country is being exploited for cheap labor.
Instead of being embargoed and sued into oblivion after this debacle, this company won "six bids". Worse still, we don't even know how many of these cases exist and we're dependent on these these foreign controlled companies for most of our medical supplies when we can't audit or punish them for these fatal drugs.
Wait till you hear what’s in baby food
Highly recommend *Bottle of Lies* by Eban. And remember regulations are justified and much is under-regulated. It takes tremendous consumer action to countervail politicians and their corporate patrons.
this video is paid by drug company
2:43 not to be annoying but saying something is used in rocketfuel doesn't really mean anything inherently. Most rocket use either highly refined jetfuel(Saturn V 1st Stage, Flacon 9 all Atlas V) highly refined natural gas(Starship and New Glenn) or Hydrogen (Space Shuttle, SLS, Delta IV)
My Metformin has been recalled a few times so far.. at least 3 companies ..
🙏
Its up too 6 companies now.
The same thing happened with ranitadine
Evil FDA
anyone know of some more in depth reporting into meds like valsartan... my mom used to take this and recently got diagnosed with a brain turmor... im gonna have to go down that rabbit hole and see if it could be related...
in this day and age. You cannot trust anything.
07:49 left behind the tree on the ground. :D
Great Reporting.
Put these people on trial for murder NOW.
I'm sorry but this woman souds like shes gonna cry every second
So?
its a sad story
Most of the generic pills are now outsourced to China and India where, the standard for the safety and quality are not really the top priority. I forgot the name of an author, but I was listening to NPR Fresh Air podcast about this crisis. You will be surprised to find out about the poor manufacturing standard these countries have.
A lot of those manufacturing facilities in India or China are usually located right next to slums. Old machines have been worn out, to a point not working properly or mixing tainted ingredients to the production. Often time, employees at those Indian and Chinese factories destroy evidence before US FDA representatives show up(Outsourcing companies tip each other)...the stories are SHOCKING.
Search on Bing or Google about NPR Fresh Air podcast about generic drug crisis...it was aired sometime last year.
This video made me not to trust the FDA
You do know the Trump lessened restriction and inspections.. hopfully Biden will reverse all these ..
The problem is like they said in the vid the fda is underfunded
Did you actually see the video?
Don't do drugs.
It’s all about money at the end of the day 😤😔
Real news
Why are the two ladies in this video coming across as shifty? Reminds me of the reporter from the wire season 5 lol!
This is a real issue, but the concept of "generic drugs" is horribly explained...generic drugs are the exact same drug as brand name (in the USA generics only have to contain 90% of the brand name dose; A generic 2mg Xanax/Alprazolam tablet only actually contains 1.8mg alprazolam...but it is the same exact drug just a slightly lower dose) what they are talking about is accidental toxic impurities that were not fully removed... But I cannot stress any further that they are the same exact medicine in brand/generic drugs...
Source: I work in healthcare
Generic is the same bioavailability as brand name..no difference
@@80sidd generic only has to be 90% as effective as brand name by law in USA. So a generic 10mg escitalopram only needs to contain 9mg by law
The problem is where and who's manufacturing those drugs
This is the cost of wealth inequality, I know quite a few people that if they were in charge of either the fda or the drug maker, they'd have stopped the continuance of this disgusting behavior that is still continuing daily all over the qorld
Get rid of the music and I don't think this could be called a "Horror Story"
This world makes me sick!
The Pharmaceutical industry is also part of their depopulation project. I took a generic HCTZ 12.5 made in China and a generic Amlodipine 5mg made in India. I almost died…..
she looks like that CIA lady
So dramatic, look at your corporations and you really should point your finger outwards. It's funny you said how the Chinese wanted to "save" money but didn't Novartis wish to save cost too? Hmm, doesn't sound capitalism to me.
true when US system fails then they have to blame china and India for no reason,
@@blackcat-mp7kh no, Americans would never do that to India as Indians have been very submissive and obedient to them, else Microsoft and Apple will not expand their customer service line (Microsoft) and full production (Apple) over to India following China's trade wars with the US started by Mr. Trump
If only Moral Education is as important as Modern Education, we wouldnt be witnessing this. Yet people just can't see it..
Not sure what is meant by modern education. Interesting point on moral education though. The question becomes who's morals? I've been to places that are obectively counter to the morals I was raised with. The morals of business are not always aligned eaither.
Cost sheet savings, synergy, leveraging global trade... reason for shifting all our crucial needs and industries overseas.
if i were an engineer, i'll also mesmerised with how the inspector identify the small peak in the EKG pulse that identified NDMA. a small thing, that make huge difference.
The EKG pulse is probably a graph of a gas chromatography detector (I am not a chemist but recently spent a night watching videos about gas chromatography so I have some basic knowledge about it).
This method splits a mix of substances by vaporizing the substances and letting them get carried through a long coil of glass tubing inside an oven by an inert gas. Depending on the type of molecule it will take longer or shorter for a given substance to reach the other end where it will end up in some kind of detector.
So, (simplified) if you know how long it will take NDMA to get carried trough the coil you can look at the graph, see that spike, notice that it is at the same time that NDMA would appear and, well, be pretty sure that your sample contains NDMA.
In reality the detector always puts out noise to some degree, so having some small peak somewhere might also be the product of not doing the gas chromatography perfectly or having some other issues (-> ghost peaks)
This is pretty interesting
How about the original valsartan? Nobody check on it.
The first part of the video literally explained the rigors in which it was checked.
You should be ashamed of insinuating that this is due to 'cheaper drugs'. It's not even remotely about that, are you f-ing kidding me? This is about greed and corruption.
I don't think they were kidding. They really want you to believe it lol
Sometimes animals are better than human
Ya, except when kibbles poops on my bed sheets. In which case animals are worse than humans.
If you look at the bottle MFG its SOLCO. Solco is a Chinese owned subsidiary in NJ USA If you look at the labels it is made in China and imported into NJ for Solco Healthcare.
donald trump was right about pharma , that US should bring back pharma back to US , and manufacturing jobs to.
ohh really like US companies are doing fair business? search for opioid epidemic and there are many more cases where us companies played with ppls life. this western media will always downplay developing countries for no reason
Yet he did fuck all to make it happen. All promises and no follow through.
Stop getting obese, eating trash, start exercising...even though its company's fault, its high time americans be healthy instead of relying on drugs for even sleep nowadays (ik some may have real issue) my grandpas is 80yo without a stick or any disorder/diseases in a 3rd world country
Sponsored by Novartis so that people stop using generic drugs
As a chemist, I never ever heard of ghost peaks. Those chemists in China were simply to dumb to perform even most simple tasks.
for FDA is dumb enough to not have proper test facility and have skilled works to to detect errors in the test ?
It's not that they are dumb. They don't care. They want to make money and will cut corners and make things up to do it.
Always progressing. We just need to make sure we learn from all mistakes even 100 years down the line.
pre covid comment=you get what you pay for&what about production enviromenrntal concerns. current covid = pre covid comment & now vulnerable supply chains concerns..
I can't take any video that starts with "Karen" remotely seriously. What's wrong with me?!
It's not vulnerabilities in a system, it is a shitty system, underfunded and with loopholes baked in by design!
Fffffuuuuuuuuu!
Runs off to check medience he has been giving his son for 3 YEARS!!!!!
this is literally propaganda for big pharma's price gouging
It is an interesting spin
Hope this doesnt deter people from covid vaccines
Covid vaccine is booming. I've been selling my own version distilled from real organic Tuscan honey right out the back of my van. I even made enough to by a bigger rice cooker which I use to keep my needles clean. Safety first!
ofc
Bribed, Chinese norm
Does this apply to all ALL angiotensin reception blockers?
as far as i know that's not the case, it doesn't even apply to all Valsartan's generics, this whole problematic is about the methode of production.
GREED
Americans need to eat healthy, stop expecting drugs to cure everything, and accept that they will die. If your unhealthy, on meds, and you die, it is not someone else's fault. It's sad but it started with your bad choices.
im so glad im european
Take me with you
buy chainlink!
Buy tinfoil !!!...You know hats for you and your friends.
@@wolfvale7863 ok boomer
@@wolfvale7863 if you had listened to me this morning your portfolio would be up 10 percent but what do i know.
Fence....? 🤠🤷♂️✌🏼
China
Another video to scare you into being angry. When in reality all you eat, drink, and live for is volatile to you. Remain healthy through food no pill will save you.
Is Bloomberg trying to be a horror show now?
Our body can heal itself all you have to do is eat right and exercise. Eat more tropical fruits and veggies you grow.
still waiting for my arm to grow back
I finally grew mine back after three weeks of celery and strawberries. Don't forget the sugar!
And Biden was in the White House house how long ????
Both political parties are complict. Wake up homie.