Acid/Base Chemistry in Medicinal Chemistry

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  • Опубліковано 29 лис 2024

КОМЕНТАРІ • 27

  • @BarrySRNA
    @BarrySRNA 10 місяців тому +2

    So how do you determine if a drug is basic or acidic based on pKa?

  • @iloveMjoda
    @iloveMjoda 12 років тому +1

    Oh thank you for replaying ! One question if you have time :D ! this has a lil to do with acids and bases which I don't get .... I know what acids and bases are. Acid are that Produce hydrogen ions (H+) when mixed with water and bases Produce hydroxide ions (OH-). My question is what acids and bases really do! are one dangerous than the other ? or cause a stronger reaction like if you put acids or bases to your hair it will change color! that's what I don't really get !

  • @zaman0103
    @zaman0103 11 років тому +1

    one of the best explanation

  • @cat875
    @cat875 3 роки тому +1

    awesome video!
    Favor for baby chemistry students like me: can you connect this to the salt form of the drug prior to it dissociating to an acid? I am just confused because the acidic form at this point will be an anion so is ionized, how will this pass through the lipid membrane?
    can you also add why the salt form of the drug is important for its solubility and absorbability?

  • @gotwalsb
    @gotwalsb  12 років тому

    it just means that the solution has a concentration of hydrogen ions (H+) of 0.0000001 moles of hydrogen ions in one liter of water. That's in the middle of the pH scale, so we call it "neutral", meaning it's BOTH an acid AND a base...amphoteric is the term.

  • @Mssugarcane89
    @Mssugarcane89 12 років тому +2

    You explain everything so clear. Thank you!

    • @gianniellis7721
      @gianniellis7721 3 роки тому

      i realize I am quite off topic but do anybody know of a good site to watch newly released movies online ?

  • @jennifernguyen3554
    @jennifernguyen3554 7 років тому +1

    your video helped me tremendously. thank you!

  • @iloveMjoda
    @iloveMjoda 12 років тому

    More back round about acids and bases !

  • @VentusK
    @VentusK 8 років тому

    beautiful podcast

  • @NithinJohnVarghese
    @NithinJohnVarghese 8 років тому

    Thank you very much.its very helpful to improve Myself.

  • @kaushiktrivedi351
    @kaushiktrivedi351 6 років тому

    Very useful

  • @mohammedalmabrouk3315
    @mohammedalmabrouk3315 11 років тому

    i'm postgraduate student & i wanna to study pharmacology so i need some help if u can about the subjects that related to postgraduate pharmacology M.D & PhD....

  • @raudoniguzikai
    @raudoniguzikai 11 років тому

    Very useful. Thank you!!! :)

  • @sonicbouy
    @sonicbouy 9 років тому

    very helpful

  • @iloveMjoda
    @iloveMjoda 12 років тому

    I know having a ph of 7 means its neutral meaning it has no effect whats so ever ! am correct ? or wrong ?

  • @dorctormido5104
    @dorctormido5104 8 років тому

    Thanks alot.

  • @Thu2za
    @Thu2za 9 років тому

    so helpfull thanks a lot :)

  • @gotwalsb
    @gotwalsb  12 років тому

    This podcast assumes that the viewer has taken basic chemistry and knows what acids and bases are. This podcast ONLY talks about acid/base chemistry in drug design. There are plenty of other resources on introductory acid-base chemistry!

  • @NextgenBeast93
    @NextgenBeast93 6 років тому

    He was talking too much and going too fast people can hold no more than 7-9 things in their memory at once.

    • @cat875
      @cat875 3 роки тому

      you can adjust the speed of the video

  • @doctorfaranali7239
    @doctorfaranali7239 8 років тому

    Bakwas

    • @zenab9976
      @zenab9976 8 років тому +1

      What is the mean of bakwas

    • @JaiSinghDhaliwal
      @JaiSinghDhaliwal 3 місяці тому

      ​@@zenab9976It means Rubbish