How to calculate inbreeding from a pedigree chart

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  • Опубліковано 8 лют 2025
  • Though there are computer programs, which will calculate the inbreeding coefficient automatically, based on pedigrees entered into a database, it is still handy to be able to calculate the inbreeding in less complicated pedigrees manually. Here is a short description on how to calculate the inbreeding coefficient from a pedigree by using the path coefficient method.

КОМЕНТАРІ • 122

  • @ThiagoBenazziMaia
    @ThiagoBenazziMaia 4 роки тому +7

    Thank you, 4 book pages of my book and I didnt understand. I watched 3 minutes of your video and now I got it. Thank you

  • @theyellowsparks
    @theyellowsparks 6 років тому +9

    Thanks so much for this! My actual textbook doesn't seem to do a good job of showing examples... I needed help on the third example and you nailed it! Thanks!

  • @fortunatembongo7200
    @fortunatembongo7200 5 років тому +3

    Thank you so much, I never thought I would understand this in 15 Minutes.

  • @moniabenadda9995
    @moniabenadda9995 7 років тому +15

    Thank you so much u cant believe how much this helped me preparing for my finals ❤️❤️

  • @anushkaathukorala_vonserendib

    One of the best videos. Explained very well and easy to understand it. Thanks a lot.

    • @GeneticsLessons
      @GeneticsLessons  Рік тому +1

      I have many more videos on this topic with more complex examples.

    • @anushkaathukorala_vonserendib
      @anushkaathukorala_vonserendib Рік тому

      Yes I will watch but as someone who do not have scientific background it takes me sometime to understand it but I am really interested in COI. Can you please tell me do you explain " Weight's or Hardiman's COI?

    • @anushkaathukorala_vonserendib
      @anushkaathukorala_vonserendib Рік тому

      I am Breeding dogs and I see COI in the dogs pedigrees and that is why I want to learn about it. 😊 By the way in the second example should the answer be 1/64? Or am I wrong?

  • @Lau_ma_lu
    @Lau_ma_lu 5 років тому +1

    I´m very happy about finding your channel! You have helped me a lot already. Enjoy your day, thank you.

  • @swethaeswathe6144
    @swethaeswathe6144 2 роки тому +1

    Easily understood sir. . thank you sir 🙏keep doing..

  • @NguyễnNgọcTuyếtNhi-p5k

    Thank you for your explanation. I'm able to solve my exercise related to pedigree analysis

  • @anushkaathukorala_vonserendib

    This video is very useful to me as a breeder because I see COI in dogs pedigrees. ❤

    • @GeneticsLessons
      @GeneticsLessons  Рік тому

      Do you know that I have a playlist - dog's breeding? Check it out.

  • @nageshgorsera8569
    @nageshgorsera8569 8 місяців тому

    thank you so much. it was easy to understand and after a bit of practice it was fast .

  • @hania.1220
    @hania.1220 3 роки тому

    You are my saviour!!thank you so much. You explained it clearly and easily⚘

  • @dicungDon
    @dicungDon 9 років тому +7

    Thank you very much for your explanation. It was clear and easy to understand :-D

  • @mhackbardt
    @mhackbardt 8 років тому +2

    Getting ready for the genetic counseling boards. thank you.

  • @richardanaru5618
    @richardanaru5618 7 місяців тому

    Thanks, you have enlightened me!

  • @suberuhamzaho546
    @suberuhamzaho546 3 роки тому

    Thank you for this explanation! You sure are gna making me pass my finals👍🏾

  • @samrawitgebeyehu7648
    @samrawitgebeyehu7648 2 роки тому

    Thank you so much! Very clear description!!!

  • @fathimanajla5913
    @fathimanajla5913 2 роки тому

    Thank you
    Clear Explanation🙌

  • @snigdhabanerjee5395
    @snigdhabanerjee5395 6 років тому

    Thank you so much sir...ur all videos on imbreeding helped me a lot sir....

  • @dheerajpatkar4080
    @dheerajpatkar4080 5 днів тому

    can i follow this video for CSIR NET Examination ?

  • @ewanentiege8931
    @ewanentiege8931 4 роки тому

    Thanks very much. Well explained n simplified

  • @erickaoctaviora696
    @erickaoctaviora696 6 років тому +1

    Thank you so much! Its helped me a lot.

  • @tabbutabbu7075
    @tabbutabbu7075 6 років тому

    Thanku very much sir....
    Very easy trick to solve the problems....

  • @Goodness_m-b4f
    @Goodness_m-b4f 4 роки тому

    Thank you so much
    I finally understand this

  • @CHEH_tf
    @CHEH_tf 3 роки тому

    thx bro that's really useful

  • @NM-tx7zm
    @NM-tx7zm 4 місяці тому

    Very helpful!

  • @imaspinner76
    @imaspinner76 2 роки тому

    I realize this video is 7 years old. BUT I can't find the answer to my question. Though I haven't watched every coefficiency video you have. I breed goats and I am just learning coefficiency in breeding. Thank you by the way for making these videos!
    I have a diagram I'd love for you to look at. But no way to send it to you.

    • @GeneticsLessons
      @GeneticsLessons  2 роки тому

      I have many more examples of inbreeding - which covers basically 90% of all cases. Please check the folder "inbreeding".
      You may send me a link to google doc - or write to my email which you can find in "about this channel".

  • @russell1841
    @russell1841 4 роки тому

    This is amazing. Thanks!

  • @arias.p4355
    @arias.p4355 4 роки тому

    Thank you very much...it was helpful 💖

  • @sarahbelaid2897
    @sarahbelaid2897 8 місяців тому

    please in our lessons they did the same like you did but for exemple they did (1/2)6 but thery multiplie the result to 4 they said because they are 4 possibilities and i didnt understand when we mutuplie the inbreeding to a number in which case and how

    • @GeneticsLessons
      @GeneticsLessons  8 місяців тому

      Just watch my other videos in "inbreeding" playlist.

    • @sarahbelaid2897
      @sarahbelaid2897 8 місяців тому

      ​@@GeneticsLessons which video please

    • @GeneticsLessons
      @GeneticsLessons  8 місяців тому

      I have many -any which have "inbreeding" in their name.

  • @nasserbenomar
    @nasserbenomar Рік тому

    MAN ! ! thank you so much .. but sometimes its 1/2 and sometimes solid 1 .. so what the differences ? because this part a bit not clear

    • @GeneticsLessons
      @GeneticsLessons  Рік тому

      I have about 100 videos on this topic - just watch more videos and you will understand how it works.

  • @fanifariedah
    @fanifariedah 7 років тому +1

    its easy to understand... thank you

  • @sashikantaparida9763
    @sashikantaparida9763 7 років тому +3

    Thank you sir.

  • @saadisabrina2527
    @saadisabrina2527 3 роки тому

    thanks so much really interessting

  • @roro3793
    @roro3793 6 років тому +2

    Thank you for your video I really enjoy learning about genetics. I have a question. Say I wanted to systematically check every individual recessive allele in an individual mouse. It's my understanding that you could use line breeding to increase the inbreeding coefficient. So breeding daughter back to father after 5 or more generations should bring you close to 100% coefficient. And at that point majority of the genes would be homozygous.
    Now say instead I made a cross between two unrelated mice. And then I took 5 daughters from that one pairing and bred them all back to the father. In theory the majority (near 100%) of the fathers alleles would be represented as homozygous across all grandchildren children but the inbreeding coefficient of each individual would only be 25%. Is this correct?

    • @GeneticsLessons
      @GeneticsLessons  6 років тому

      These videos might help you:
      Simple Inbreeding Problem and Solution ua-cam.com/video/WK-IVGvvDUU/v-deo.html
      How to Find Inbreeding Coefficient (advanced problem) ua-cam.com/video/BH07HbEkx6s/v-deo.html

  • @bibliothekdeshorrors4084
    @bibliothekdeshorrors4084 4 роки тому

    Great explanation. But I have a question. What if the common ancestor appears multiple times in the pedigree? For example:
    A appears on the fathers as the great grandfather but on mother's side as the father AND grea great grandfather. How would I count that? As one sire appears three times in a pedigree?
    Do I only take the closest one to the mother so the father?

    • @GeneticsLessons
      @GeneticsLessons  4 роки тому

      I have many more examples of inbreeding - just search my channel.

  • @Chrysalis-y4n
    @Chrysalis-y4n 2 роки тому

    Thank you so much❤

  • @NourBellil-mb1hp
    @NourBellil-mb1hp 10 місяців тому

    Thank you so much !

    • @GeneticsLessons
      @GeneticsLessons  10 місяців тому

      Today, I am starting a new series of short videos debunking the 'Out of India' theory.
      ua-cam.com/users/shortsnv3YrBrGXdU

  • @karinkburns
    @karinkburns 8 років тому +1

    Thank you. Ochin intereshna.

  • @luizfilipepaiva2777
    @luizfilipepaiva2777 2 роки тому

    Can i use that to calculate inbreeding in humans..?

  • @user-cz3bf6cb4c
    @user-cz3bf6cb4c 3 роки тому

    is this wright or handimans method?

    • @GeneticsLessons
      @GeneticsLessons  Рік тому

      Watch my new video: How closely Adolf Hitler's Parents we related? ua-cam.com/users/shorts8kajiIuUwxw

  • @Shagunagarwal.
    @Shagunagarwal. 4 роки тому

    Mannn u r the best

  • @pastat40
    @pastat40 8 років тому

    What if some individual already was inbreeded? For example, what if individuals C and A in your third case were inbreeded. Lets say C had 0,5 and A had 0,25. What then?

    • @GeneticsLessons
      @GeneticsLessons  8 років тому

      Than it would be reflected on inbreeding coefficient you have to multiply by this inbreeding numbers.

  • @esoheiyare9874
    @esoheiyare9874 8 років тому +1

    Thank you very much

  • @XXTheDonkey
    @XXTheDonkey 5 років тому

    I have a hw problem that starts with 2 separate lineages that eventually come together...and im very confused

    • @GeneticsLessons
      @GeneticsLessons  5 років тому

      Check my playlists - I have tens of videos on this topic.

  • @reemaxx2080
    @reemaxx2080 7 років тому

    What does it mean when the numbers are bigger or lower? I mean in your example baby no2 is 1/32 and baby no3 is 1/16 . Dose it mean that baby no3 is inherting more from thier parents and ancestors ?
    Dose it have anything to do with passing and pushing harmful genetics?

    • @GeneticsLessons
      @GeneticsLessons  7 років тому +1

      The bigger the number the bigger probability to inherit SAME allele . Say probability 1/16 is bigger than 1/32.

    • @alokneet
      @alokneet 5 років тому

      @@GeneticsLessons Nicolay

  • @adityakhanijo7433
    @adityakhanijo7433 4 роки тому

    Amazing!

  • @arisgolseen2693
    @arisgolseen2693 4 роки тому

    What does it mean if "No common ancestry was found in 5 generations"?

    • @GeneticsLessons
      @GeneticsLessons  4 роки тому

      Same ancestor from both mother and father side.

  • @Yue_Jin
    @Yue_Jin 6 років тому

    explaining how u get the 1/8 or 1/32 would be of great help.

    • @GeneticsLessons
      @GeneticsLessons  6 років тому +1

      This is exactly what I do in this video.

    • @GeneticsLessons
      @GeneticsLessons  6 років тому

      Here is another video on this topic: ua-cam.com/video/nePPKuwphn8/v-deo.html

  • @GeneticsLessons
    @GeneticsLessons  5 років тому

    Watch my new video:
    "Inbreeding and Loss of heterozygosity explained" ua-cam.com/video/5NYEJ1XbhQ4/v-deo.html

  • @elijahavante2127
    @elijahavante2127 6 років тому

    If offspring “I” produce offspring Male (M) and Female (F) and inbred produces offspring (O). What will be the inbreeding Coefficient of (O). Thank you awesome videos. Subscribing for more

    • @GeneticsLessons
      @GeneticsLessons  Рік тому

      Watch my new video - How to live much longer: ua-cam.com/video/nW4ma5Y5liE/v-deo.html

  • @KateeAngel
    @KateeAngel 8 років тому

    Вам нужно работатт над произношением. Сильный русский акцент на английском - это что-то ужасное. По себе знаю) А видео очень информативны!

    • @GeneticsLessons
      @GeneticsLessons  8 років тому

      Я работаю, у нас в университете полно иностранцев которые говорят с акцентом - и ничего ужасного..

  • @walaaesseid9348
    @walaaesseid9348 2 роки тому

    thank u

  • @dauren.00
    @dauren.00 3 роки тому

    Русский боженька, спасибо что вы это объяснили

    • @GeneticsLessons
      @GeneticsLessons  3 роки тому

      Пожалуйста. У меня еще есть много видео на эту тему с более сложными примерами.

  • @GeneticsLessons
    @GeneticsLessons  4 роки тому

    New video: Pedigree vs. Arrow diagram (path analysis) ua-cam.com/video/4HeLMpQra7Y/v-deo.html

  • @sheikhseerat7105
    @sheikhseerat7105 5 років тому

    Helpful

  • @bonimaxwadenmark1
    @bonimaxwadenmark1 5 років тому

    Am learning here

  • @GeneticsLessons
    @GeneticsLessons  6 років тому

    Watch my new video:
    Adolf Hitler: Genetics vs Eugenics ua-cam.com/video/D7cFfS3KfY0/v-deo.html

  • @pseudopetrus
    @pseudopetrus 2 роки тому

    Now I know how I can marry my chickens!

  • @ninalilija7039
    @ninalilija7039 3 роки тому

    how is 1/32 + 1/32 = 1/16??? please help

    • @GeneticsLessons
      @GeneticsLessons  3 роки тому +1

      1/32 +1/32 = 2/32 = 1/16
      same as 1/4+1/4=2/4 = 1/2

  • @dankobucanac4809
    @dankobucanac4809 8 років тому +1

    Hello Nikolay, please check your Gmail inbox...

  • @pavelgrigorchuk5568
    @pavelgrigorchuk5568 7 років тому +1

    А почему не на русском??

    • @GeneticsLessons
      @GeneticsLessons  7 років тому

      Всетаки строительство 2000 церквей за последние 5 лет не прошло даром :-) Плоды не заставили себя долго ждать.

  • @alokneet
    @alokneet 5 років тому

    Nicolay

  • @molekul8085
    @molekul8085 5 років тому

    your accent is so hard

  • @alokneet
    @alokneet 5 років тому

    Nicoli

  • @TonyTorzido
    @TonyTorzido 6 років тому

    daddy nikolay

    • @omp199
      @omp199 4 роки тому

      If Nikolay was your daddy, and you made a baby with him, what would the coefficient of inbreeding of that baby be?

  • @anthonylewis7812
    @anthonylewis7812 3 роки тому

    thank you so much

  • @allblackeverything405
    @allblackeverything405 3 роки тому

    Thank you so much