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- Опубліковано 14 жов 2023
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0:12 Building Blocks for Treatment Plan
0:42 Who is the lecture for?
0:51 Advanced Cancer outside the Prostate
1:03 What is the problem?
1:27 Oversimplification?
1:49 Too many diagnostic options?
1:59 Multiplicity of practice and business models?
2:24 Misunderstood terms and concepts?
2:40 Outdated perceptions?
3:04 Too much information
3:30 Goals of this presentation
4:02 The Basics of Advanced Prostate Cancer
6:13 "Updated" Biology of Advanced Prostate Cancer
6:38 "Clonal" theory of Cancer
6:45 The Heterogeneity of Prostate Cancer Cells
10:20 Systemic treatments as of 2023
10:48 What is a systemic therapy?
11:28 Suppressive therapies
13:05 Cytotoxic therapies
14:12 Mechanism of Action (MOA)
14:52 Testosterone promotes prostate cancer growth
16:01 GnRH Hormone Therapy
16:27 Anti-Androgen Hormone Therapy
16:58 Hormone (Castrate) Resistant Prostate Cancer
17:28 ARPI Hormone Therapy
18:55 Chemotherapy
19:55 Immunotherapy
20:37 Radioligand Therapy
21:40 What's the best way to create a treatment plan?
25:03 Abbreviations pertaining to forms of therapy
25:46 Case study: Newly diagnosed Advanced Prostate Cancer
27:39 Triple therapy
28:51 What if you didn't start with Triple Therapy?
29:48 Case 1: Failing HT?
32:51 Chemotherapy first
34:12 Case 2: Failing HT + ARPI?
38:50 Less differentiated = more aggressive cancer = LESS PSA & PSMA
39:36 PSA Zero
40:24 Case 3: Failing HT + prior CHtx?
42:19 Case 4: Failing HT + ARPI + prior CHtx?
45:35 Proper "care and feeding" of your treatment plan
46:00 Regular and comprehensive follow up is key
47:13 Prior genetic testing
49:36 Updating genetic testing
50:43 Mutations relevant to PARPi
52:13 Mutations relevant to immunotherapy
54:07 Mutations relevant to PARPi or immunotherapy
57:05 Regular and comprehensive follow summary
57:24 Direct treatments as of 2023
58:15 DIY Combat Manual for Beating Prostate Cancer Videos
59:02 Multiple ways that residual disease can be eliminated
59:21 Chest surgery example
59:47 Radiation therapy example
1:01:25 Minimal invasive procedures
1:02:33 Misunderstood concepts
1:03:18 Stand-of-Care
1:05:11 Guidlines
1:05:58 Clinical trials
1:09:43 Oversimplified view of disease
1:10:08 List to bring to with you to physician meetings
1:10:48 Dr. Kwon's Team
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Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians, for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
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How can I contact Dr. Kwon? I am a fellow guitarist and stage 4 PC on triplet therapy, I have a couple of questions for him :-)
Thank you. Videos with subtitles are great for foreigners who are not that good at english. These people can turn on automatic translation to any language.
I have prostate cancer Gleason 3+3=6, I'm 62 and have been watching this channel for a week or so. My father, died this year, age 93. He had his prostate removed in the 1980's (age~ 58) surgically from the rear (at that time this was state of the art and promised less side effects). Then a few months later, he had radiation for three or four months. The cancer returned and his PSA was over twenty in around ten years. He was put on hormone therapy every time his psa would go up very quickly to the upper teens or over twenty. Anyway, his prostate cancer was in his bones ect.. The last three year of his life he began taking some sort of chemo tablets, two per day. This was a last resort by an oncologist and he lived a few more years and was fairly happy despite having to run to the mens room often. Let's hope we can all live to our nineties cancer be darned.
This just happened in the land down under. Follow them.
>>Undetectable levels of Prostate Specific Antigen (PSA) have been reported from the first patient with metastatic castrate-resistant prostate cancer (mCRPC) to ever receive two cycles of Clarity’s 67Cu-SAR-bisPSMA at the 8GBq dose level. PSA is a marker of tumour burden, clinical response to treatment and an indicator of the recurrence of disease for prostate cancer.
Don't know your biopsy results, PSA, ..., but GS6(3+3) cannot metastasize, so it means that the cancer should be localized only in prostate.
You should definitely buy and read the book by Mark Scholz MD: "The Key to Prostate Cancer" from 2018.
You should consider also other options than surgery: Active Surveillance and radiation.
Thanks for sharing this.Really encourages not to loose hopes
The City of Hope is adding Ivermectin to TNBC treatment, University at Glasgow is adding Mebendazole to Docetaxel for PC, Dr. Marc-Eric Halatsch is using Itraconazole in a 9 repurposed drug protocol for Glioma and Glioblastoma. Dr Tom Rogers YT video on Artemisisin and Fenbendazole has some comments you may be interested in.
Fascinating presentation. I am not like a lot of others here because I am just starting and scared out of my shoes. I don't want to make an error. Local Urologist in Greenville SC. I want to do what is best but have no idea where to start. Travel to someplace like Mayo?WU here? of 6 segmennts Gl score of 6 in 5 and 7 in one. However my PSA is>30 which started this.Dr Kwon is the first person who has given me any hope at all. PET Scan scheduled locally.
I found the presentation on the topic of prostate cancer to be the most amazing and comprehensive one I've seen to date. I would like to express gratitude to Dr. Kwon and the PCRI (Prostate Cancer Research Institute) for the presentation and for sharing. I am 66-year-old individual with prostate cancer, specifically a Gleason Score (GS) of 9, and have undergone a prostate operation (2017), hormone therapy, and salvage radiotherapy (2021). My PSA (Prostate-Specific Antigen) has risen to 0.12 ng/mL. I am in a stage of contemplating their next steps in treatment and found the information session to be educational and helpful in providing guidance for their future treatment plan.
I'm 60 and had a radical robot prostatectomy 7 months ago. I just had a PSA .10 and I am now on Androgen and started 48 radiation treatments as we think the cancer is in my Lymphatic near operation site nothing showed on bone scan or other scans, but we believe this treatment plan should be done anyway as one of my nodes that was removed had cancer. I only had 5 radiation treatments so fare and only had talked to doctor about my treatment plans for only 5 minutes, so I know very little about my condition and treatments at this time. Thank you for helping me get up to speed. I'm so hungry for info that I hit up all sites to learn all I can, and this site was the most informative by far.
There can be no better lucid and indepth explanation all about prostate cancer and it's ramifications. I am an advance prostste cancer with metastatis..but the way this dr is pressenting so passionately and qualitatively , at 72 I wish I was a dr like this dr ..I have forgotten about my cancer after listening this dr .great..i am from India
This is the best summary I have ever seen -- excellent information, clearly organised and presented!
Excellent overview of treatments and options - thankyou!!
What a clear and didactic presentation of prostate cancer, and it's different forms of treatment!!!!! My doctor never informed me anything about this and just sent me to ADT for 9 months. And now I am worried to learn that ADT does not kills the cells so my treatment may extend to years ,
As usual, Dr, Kwon is articulate and to the point. Best presenter out there!
Probably the most concise and informative video I have seen since I was diagnosed with prostate cancer in 2018. wish I saw back then.
Thanks to you Dr. Kwon and your entire staff.
Dr. Kwon, this presentation was excellent and extremely informative. I will be meeting with my doctor shortly and plan to discuss some of your points presented here. Thank you again.
Excellent presentation! Thanks for providing a great guide for patients.
Great video that covers all the important points of advanced prostate cancer treatment in plain English. If you want a detailed overview and you are new to this disease, start with this video.
Dr. Kwon's approach to curing advanced prostate cancer rather than using a palliative approach gives hope to afflicted patients.
Thank you, Dr. Kwon!
Thank you so much for this clear and informative video!
My husband is a Mayo Clinic/Rochester patient- diagnosed with low volume mets , Gleason 9, 2 1/2 years ago. Initially treated with 26 rounds of radiation and has been on ADT (Lupron/Abiraterone) since then. PSA remains at
Dr. Kwon and his team and associates are national treasures. I remember sitting on a chair for my first visit and the APRN introduced herself and asked me if I wasted to pursue containment or cure. I was speechless. Cure was not on the radar. Cure is not guaranteed. An associate said I had a 14 percent chance of not being cured. Meeting Dr Kwon was one of the most awesome moments of my life. I have trouble believing he is human and not angelic. Humility, compassion, empathy and caring do not always accompany genius. May God and the real angels protect and bless Dr. Kwon as he is a National treasure and his team sent by God to battle for our lives. Hopefully his understanding of Prostate cancer will spread across the world. God bless the Kwon Team. Thank you.
Where does he work?
Wonderful presentation.. factual and clearly explained and enunciated
Thank you Dr. Kwon
Dr Kwon has been my Doctor for over 3 years the guy knows what he’s doing so listen to him. I started with stage 4 and a PSA of 93 and a Gleason 8. My first doctor started me with 44 radiation treatments. After that luckily my wife got me into Dr Kwon. I have had several different treatments that helped but always came back.I have done 5 of 6 treatments called Lutitium 177. So far my PSA is undetectable nothing new and nothing showing. I am hoping for a remission to last for longer 6 months. I’m very fortunate to have Dr Kwon and once he gets ahold of you he doesn’t let go. Thanks for all he has done.
Where is he located? Thanks
Great Job. God bless the team.
Thank you once again Dr. Kwon.
Thanks! You folks are appreciated!
Dr Eugene kwon...too good ..i am touched with gratitude that this presentation is too good for pstients awareness..
Excellent presentation.
Thank you very much Dr.Kwon.
Absolutely brilliant presentation. UK based here, starting PSA over 1300. Enzalutamide working so far. Long conversation with my oncologist needed now.
Hi. Also in UK. PSA of 310 with multiple bone lesions. Did you start treatment with 14 days Bicalutamide followed by Decapeptyl. If Decapeptyl how soon after did you start on Enzalutamide - was the latter your choice of drug. Thanks
@@stitcheruk1150 I started with a Bicalutamide for 28 days. I then started on Prostap (Lupron) ADT injections, first one was one month then quarterly. Started on Enzalutamide 8 weeks after diagnosis. That was over 3 years ago. PSA currently 0.03, incredible really. Good luck to you.
@@stitcheruk1150 I should add that I wasn't given any choice on the drug. Oncologist just said we're giving Enzalutamide instead of chemotherapy because of Covid.
Absolutely brilliant! Thank you for the privilege of becoming semi-competent in this area. Just finished exhaustive Suppressive Therapy with a rising PSA, thanks to your video, I now have reduced stress an road map to success! Hopefully I can access Chemo and swing back to ARPI if it doesn't work. Thanks again!
Extremely interesting presentation.
I was diagnosed in March with 525 PSA. Metastatic. Prostate cancer in 5-6 areas (back, ribs, pelvis). Started Orgovyx right away and NUBEQA. Soon after, Lutetium. So far I've had 4 of 6 infusions.
PSA down to 2.3 so far and next read-out should be around 1.1. No increase in lesions and decrease in cancer presence.
I have been told that there is no "cure" for what I have, so it's encouraging to hear a different perspective here. My own fight has involved shifting to a plant-based diet (not a big shift), daily resistance exercise, white, green and black tea drinking, and a lot of quick walking/fast running in spurts (morning and evening).
For me, hot flashes are minimized significantly by exercise and some supplement additions (D3, B1, Calcium, Magnesium Glycinate, 5-HTP and Melatonin). The drugs (Orgovyx mostly) definitely increase my anxiety (something I had little of before), but, as I just mentioned, all side effects are reduced or neutralized by vigorous exercise in particular.
I've gained no weight, have gained muscle mass, and focus on this form of exercise as loss of bone and muscle mass is common.
My "fantasy," which is to ultimately take ADT's in intervals, or go off them altogether, seems a little closer after this discussion.
Appreciate this presentation very much.
Very thankful for pcri also glad u all get together to share info,my situation below ,next message
thanks for having a sense of humor! and adding new words to the vocabulary. I have 4 + 3 and I'm trying to get HiFU but what a wait.
very useful information and explanation, thank you
Clear, calm and thought provoking thank you .
Thank you very much Dr Kwon for sharing such important information for those of us trying to understand the complexities of Prostate Cancer. This info was easy to understand and take notes. Nice job...
Thank you for a great presentation it was very helpful
A big thank you for all the information in this video. 58 yrs old, diagnosed last week with skeletal metastasized prostate cancer PSA 2,000, Gleason score of 9. Started Firmagon yesterday, meeting the oncologists tomorrow to discuss starting radiation treatment within the next three weeks. I now have a lot more confidence in the diagnostic process (PSA, prostate biopsy and bone density scan completed) and will take the lists with me tomorrow. Thanks again.
Please update as and when. As another person suffering, it’s somewhat reassuring to follow a person’s journey through this awful disease.
@@stitcheruk1150 Are you really interested in an update?
@@Mark_Lacey Most certainly - I was also diagnosed two weeks ago with skeletal ( multiple lesions ) metastasised prostate cancer, although my PSA was 310. Also have had a biopsy. No idea how long I have had it as no symptoms apart from getting up in the night. Initially refused a PSA by my doctor in 09/2022, who said ‘come back if anything changes’. Nothing changed, however I decided to ask for a Health check which did not include the doctor. At this check in 09/2023 I asked the nurse to also do a PSA test as part of the bloods - this came back PSA 310. So far been given 14 days Bicalutamide ( finished those ) followed by a Decapeptyl injection (3mg) at 14 days to be followed by a larger dose of 11.5mg a month after the first. Still ‘researching’ - hence my interest in your situation and treatment. Thanks for getting back.
Mark - I can no longer see your reply to me.
@@stitcheruk1150 I think because I tried to put my email address here comments got deleted.
Wow! Thank you again for such a detailed presentation. So much data!! Like your other presentation, I will return to this several times to get it in my head. I was a Gleason 9 and had a RP including lymph nodes and all surrounding tissues, but 2 years out still have an undetectable PSA. But I continue to pay attention to the progress in the treatment of metastatic disease.
Thanks for sharing, I have GS4+4, 66YO, 2 years into the combat against PC
Dr Kwon,
Thank you for your excellent presentation.
Please direct me to the PDF file documents that I can take to my doctor.
It's as amazing to hear you quoting a CCR song from the 70's iirc, as it it to hear your depth of knowledge regarding PC. Thank you for this priceless dissertation.
What a goldmine of informations. And I love your humor, and all those allusions, musical or onthers. Thanks a lot !
(p.s. where I could find the 176 hours presentation please ? )
Excellent overview. Spouse has been diagnosed with Gleason 9 with mets to bone and lymph in the 12th month of ongoing treatment for “prostatitis” with antibiotics. I recommend you get an MRI right away when symptoms start, especially when your father had prostate cancer.
Hi from the Uk, following for some considerable time,❤ Eugene and his presentations , has been 12 years to the day presented to oncology with T3a G7 margins clear, up to this point I’ve mostly flatlined PSA from 0.01 to 4.6 since surgically the prostate being removed. As I type it has moved into bone with PSA 40 doubling time four weeks , had the first Chemotherapy last Monday I’ve been treated with the same plan more or less as presentation here suggests.
0.42 after eight sessions of chemo to date
Wow! Great video, I have gone through a lot of treatments and, according to my doctors, am kind of at the end of options except RA223. Your info gave me ideas about what to do now.
For my localised Prostate Cancer, Cyberknife turned out to be a most effective treatment. I had a PSA of 52 and biopsy showed Gleason 3+4 around 7 months back (just before opting for Cyberknife). No adjuvant therapy. Today my PSA is down to 2 with no trace of the disease. Absolutely no side effects. Best to do some research before jumping to any treatment plan out of panic.
Thank U so much!!! 38 months in ,small break from trelstar,but,,failed 1st at16 months then xtandi failed at26 months ,then abirotimone failed ,, branched me out. To a cancer center in SC,,,psa up to 250,,,did taxatere,,knocked it to 125,,,then bone Mets radiated psa to24,,then jeftona only down to 8,,psa creeping up to48 then more radiation same spot but other hip started hurting ,still on trelstar psa124 ,,skipped trelstar 2 months psa now148,did geno test said I was bracket 1 and 2 positive ,did a month of Casodex psa is148 ,,,dr said he could try new med which I hope is a part thatU made it seem might help for that?thanks again for this super packed info,,I feel better already, I've always had great faith in JESUS ,,THAT IS SO IMPORTANT ALSO ,,WERE ALL IN HIS HANDS ,YOUR AWSOME TO DR
I was diagnosed with prostate cancer in 1993. PSA was 300 with every bone in my body having cancer. Given 6 months to live. Oncologists told me Thai is unlikely I will walk in 3 months. My urologist decided to try Lupron to see it would help. Also added casidex.
Within one year my PSA dropped to zero.
Stayed that way for 28 years testosterone was less than 3.for the last 2 years, psa started creeping up. Reaching 3.3 this year. Started Nubeqa earlier this year. PSA dropped to 0.2.
Getting weaker each year. Can’t open soda bottle. I will be 84 next year. Made decisio last week to stop all treatments. Will test again in 3 months to see results.
What do you think of my decision?
Thanks for this very personal info. It's good to know what works for different people. You might want to edit the part where it says Thai. obviously you meant 'that' but DAC! dam auto correct can sometimes be wrong.
U are a fighter u don’t surrender keep strong take vitamin supplements and drink lemon ginger infuse water 💦 Witt a half spoon of Turmeric God bless 🙏
You know your story. Heroic stance vs prostate cancer. It’s a Quality & Quantity journey. I salute you and admire your courage.
Low carb/sugar. D3w/K2-MK7. Cod liver oil, alpha lipid acid. TUDCA! Vit C B's. Minerals mag pot zinc. AND immunological mushrooms, especially phellinus linteus, but including chaga, ganoderma applanatum, tramedes versicolor. Adaptogenic tea would be helpful, too, with eleutherococcus, schizandra, rhodiolia, the logic I'm carthamoides, and ginseng. Research available on pubmed. In particular read on phellinus linteus mushroom. There's more if you have other factors such as weight, insulin, blood pressure issues; they can all be addressed though. I admire your courage!
Automistake: rhaponticum cartamoides
Thank you for this fantastic presentation. It is possible to get a link to your lists. Would be helpful for next consult with my husband and urologist. Thank you.
"10" presentation Doc~
Interesting
Exellent presentation, where can I find information based on possible microscopic prostrate cancer and what treatment plan is recommended for this case?
This is very timely for me. I was treated for Stage IV Prostate Cancer that had spread to my lymph nodes, with a Gleason of 9, in 2018. I had ADT for 18 months and IGRT and was doing very well until a few weeks ago, when my latest PSA had jumped to 30! I’ve just done a PSMA PET scan and it shows that the Cancer has spread to many places in my bones. I just went back on 1st Gen ADT, and I’m looking at options. My Doc had said that maybe I can do Lu177 at an earlier stage, along with 1st and 2nd Gen ADT. We don’t know if they’ll allow me to do Lu177 at this stage, but it might be possible since I’m in the Philippines and they’re not as strict about when to use it here. The argument is that using it earlier, when the Cancer hasn’t become resistant to ADT and therefore more hardy, might have better results. If they won’t allow it, I’ll do Chemotherapy and then do Lu177 if it seems to be coming back. Im hoping to buy as much time as I can, until new treatments come along. What the Doctor said about using these treatments earlier, seems to make sense to me. Im only 61, so I think my body can handle more treatments now, than when I’m older. This presentation was excellent and made me believe that I’m on the right track with triple treatment and adding either Lu177, or Chemo to my treatment plan.
Dx maj'21, dit/do docetaxel, lupron and Xtandi, Zometa for skeletton, march'22 I begann LU177 at my own initiativ, I'm fine 🙏
Hi, very sorry to hear about your current PC, I’m 61 , and recently had a PMSA PET scan as my PSA jumped to 5 , waiting for results.
I’ve had it since 2021, I was just wondering with the jump to 30 and having a terrible result from the scan , were there any symptoms , I ask as at the moment I feel fine, I have come to the conclusion this illness is a sneaky bugger..
Anthony, I had a bad lower back for many years, so I was in constant back pain, so I assumed the back pain was just increasing due to age, however it turned out that exactly where my back issues were, is where the Cancer migrated to, perhaps because it was already inflamed there and the Cancer was drawn there due to the existing damage. I'd also had a broken rib before, and I was having a bit of pain where that had long since healed, so I stupidly assumed that maybe it was just some arthritis there from the previous damage, but once again, the Cancer migrated there as well, and spread to the ribs closest to that area. So the symptoms were really increased pain from other existing injuries. Other than that, nothing else. Also, I'm on Zytiga now, as well as Zoledronic Acid infusions every 28 days. They won't allow Lu177 yet until I've done one round of Chemo, however, my PSA is down to 0.02 now, so the Doc is saying that maybe we'll wait on the Chemo until it seems to be climbing up a bit again since the Chemo attacks dividing cells, and it looks like the hormones have stopped them from doing that, at least for now, so giving me Chemo at this stage would be counterproductive. He'd rather get me through six rounds of the Zoledronic Acid and do another PSMA PET scan and see what things look like.
Thanks for your reply, glad to hear PSA down and you have future options, we are all guilty for putting some symptoms down to age or previous injuries, wish you all the luck moving forward 👍
Thanks for the great informative video. Is there any way to get the slides from this presentation? Once again, outstanding job. Keep up the good work.
Thank you Dr Kwan.
I am so thankful for this presentation, it makes advanced prostate cancer management more understandable. I do have a question, is there a link to download the ' List to bring to with you to physician meetings' ? Thank you in advance.
Thank you very much doctor!! Incredible and open mind presentation, my father is battling with cancer right now his second chemotherapy and many Arpis!! Thank you for the presentation God bless everyone of the Mayo Clinic and the prostate center. I live in Bolivia how can I contact the doctor
Is a handout of the presentation slides available?
Thankyou for the best explanation of options ever. Is it possible to hire you to direct my husbands treatment via video meetings while receiving the treatments locally in the Seattle area? My husband has treatment history with Providence Cancer Center (Everett, WA) and has approached Fred Hutch (Seattle) for a treatment plan as the ADT and ARPI treatments have failed. Suggestion - can you provide your presentation and lists in printable form - with letters on a white background instead of black background?
This may or may not be of use to you, I'm hoping it is.
>>Cooperating with the downregulation of homologous recombination repair ability after AR signaling inhibition, ivermectin increased intracellular DNA double-strand breaks and finally triggered cell death. Our findings demonstrate the anticancer effect of ivermectin in prostate cancer, indicating that its use may be a new therapeutic approach for prostate cancer. >On the other hand, IP6 treatment was able to significantly decrease the expression of Shh across all the study time points.
Thanks so much for this presentation, really well organized and has provided me with the knowledge I need to have when I go meet a different Oncologist to discuss my treatment plan. I had low PSA scores 4.5, high Gleason scores of 6+ and 8+ on two core samples. Completed 44 EBRT radiation treatments, and have been on ADT Hormone Therapy for 9 months, they want me to do 9 more months. This video has confirmed what I thought which is that sufferring through 18 months of ADT Hormone therapy is really palliative and not curative. So again, thank you for all you do and taking the time to publish this video as it at least lets me prepare for the next meeting on Jan 19 to discuss more "optimal" curative therapies moving forward rather than just waiting another year to determine if what's been done has really addressed the aggressive PC.
All the case studies were high volume disease. I’m curious if Dr. Kwon would still use Triplet Therapy for a pt with low volume disease?
Hoping AOH1996 will bear some benefit.
It's interesting that there is no mention of metabolic therapy.
Doctors / Survivors, need your help.. my dad is going through the advanced prostate cancer with metastatic to bones.. he went through turp surgery and then hormone therapy for few months, in Oct 2023 he had 3 cycles of Chemotherapy but the PSA went up to 59, chemo was stopped and given Enzalutamide for 2 months psa went down from 59 to 26, he felt better but eventually he started feeling the bone pain again ; now the doctors gave radiation therapy and apalutamide.. he is very drowsy, tired and I could see he is loosing his strength slowly; any other treatment methods or meds that I should check for my dad to get him back to the normal life.. we are from India and dad gets treated in Chennai .. I appreciate your comments or support to save our family!
Next week is the date that I hear just how bad my cancer is. And seeing that dandelion portion of the video, just wants me to throw up my hands and say f it. I just hope that I have a fighting chance, but even the word fighting means that I lost.
What are the sideeffeckts of chemotheraphi
My Prostate was removed and the PSI was 1.4 but I did'nt follow up due to Insurance and Jobs.Finally got Insurance & tested. My PSI is 43,400. At the Hospital now . I will update you.................
Praying for you.
Please reach to our helpline is you need any help: pcri.org/helpline
We stand with you and hope and pray for the best.
My dad is 67 yrs old he has been diagnosed with prostate cancer which has metastised to the lymphnodes and pelvis girdle as per CT scan and mri with psa of more than 100 with Gleason of 8 he has been put on zoladex injection, zytiga and casodex for 3 months then once tumor burden has reduced he will start on radiation therapy, how aggressive is this treatment kindly reply many blessings to you all
Is it possible to get this standard of treatment in Canada?
Hello, we are not able to answer case questions on our comment section but we can help you through our Helpline who can speak with you either by phone or email. Here is the link to contact them: pcri.org/helpline
I am 68 years old i got malignant biopsy on prostate i got surgery last 2021 and it was growing up 38 gm what should I do Sir?
This video was very good but it doen't help in my husband's situation. He has been prescribed all categories of treatment but his PSA is rising - now 500. What are the next steps? His doctors have said therr is no available treatment at this present. A video about the next step would be helpful.
I would call the helpline of this pcri channel.
Urolift completely and permanently destroyed my life !!!! Now I am faced with my new urologist wanting to do another surgery (greenlight) to correct to the botched UROLIFT procedure.
I am told I would have to self catheterize everyday possible for the rest of my life. My symptoms now are WORSE than before Urolift. Please be advised and don't say I didn't warn you if you get this procedure !!!!!
My dad was diagnosed 18months ago at the age of 74 with prostate cancer, he’s undergone 4 surgeries then started taking chemotherapy, he took 8 sessions of chemo, just finished chemo last month, but again there’s prostate enlargement and blockage of urine.. Dr suggested surgery again but my Dad said I can’t undergo any further surgery because of poor health now. We are really worried about them, he’s pain in all body, he cries bcz of body ache.
What four surgeries? 🤔
Hello so sorry, perhaps he can see a pain management specialist
What about the new treatment vidh laser, to heat upp the tumor, Clinical Laser system from Sweden have invent this , i th8nk you have this system
Recently on a Joe Rogan podcast with Graham Hancock they discussed using a “repurposed” drug fenbendazole for cancer treatment. This treatment is becoming very popular because of the success rates.
Minimum downside with a cure on the upside. What do men have to loose?
Isn't that a dog wormer? Any clinical trials?
Im 65yrs old and for the last 14 months my psa has been 12.4. My Urologist sent me for an MRI scan and the results came back as no cancer but showing inflammation and enlarged prostrate. My Urologist told me ive prostatitis which is the reason for high psa. I mentioned a biopsy but he assured me their is no need for biopsy as their is no target for the needle as no cancer is showing.
My Dad and Grandad both passed away with prostrate cancer. So im a little nervous. This morning i had another psa blood test hoping it has come down 3 months after my last blood test. Need to wait a week for results. 🙏
What is your PSI Rad score given by the radiologist? It should show on your report.
@@tatianaschoenfield9819 my mri scan on my prostrate says it's normal and classified as PIRADS 2. Whatever that means...
@@stephenpisani1730Your Dr. is right. If there were cancer it should show on MRI. This is what showed on my spouse’s MRI and triggered the biopsy. You responded PI Rad 2, which means means low, cancer unlikely to be present. But get another opinion maybe because of the elevated PSA…
I am 65 PSA went from 4 to 4.5. Had the MRI done, they initially told me not to worry, they said the scan showed some small spots, which might, or might not be cancer, and they would follow up with me after Christmas 2022. Fortunately the urologist proceeded with the biopsy procedure, although he and his assistant were sure it wouldn't show anything serious. Well turned out two biopsy cores scored a 7 and an 8 on the Gleason scale. Had 44 radiation treatments and am going through ADT hormone therapy for 18 months, Ugh... I am not doing well with the side effects, bone mass and muscle tissue loss are significant. In any event, I would go to another Urologist with your results so far and get a 2nd opinion about getting biopsy done. I am going to get a 2nd opinion myself from another Oncologist as I'd really rather do something curative about the cancer rather than put it to "sleep" for 18 months and then find out at age 67 that metastasis has occurred. Good luck
I had a MRI with no showing. But later had a biopsy and PSMA scan and cancer was present. Gleason 8, but not outside my prostate. Now seeking the best possible treatment. Listening to all this, it's all a crap shoot. Changing diet, and metabolic may be the way for me.
My psa was 3.9 Gleason 9 , had surgery, 2 years later psa went up to.20 had radiation 37 treatments, 1 year later psa went to 6.8 been on Lupron for 3 years, so far psa .001 , but side effects are awful
What side effects, those of the ADT or of radiation? I am G9, have been on ADT, both generations, for 4 montgs and now contemplating radiation, but concerned about side-effects. Thank you for your comment.
Have followed you for several years and wonder why you have now eliminated beam radiation from your list. Before, you have stated that radiology treatment like SBRT would become the standard for treating advanced metastic prostate cancer.
Opps - should have waited until the 95th minute. Sorry
My father had a surgery first week of this year 2024
Gentlemen, grab your ankles!
PCRI needs to comment on this recent revelation.
>>Undetectable levels of Prostate Specific Antigen (PSA) have been reported from the first patient with metastatic castrate-resistant prostate cancer (mCRPC) to ever receive two cycles of Clarity’s 67Cu-SAR-bisPSMA at the 8GBq dose level. PSA is a marker of tumour burden, clinical response to treatment and an indicator of the recurrence of disease for prostate cancer.
The response you're looking for is in this video: 1:05:58 Clinical trials
@@FightingProstateCancer clinicaltrials.gov/study/NCT04868604
@@FightingProstateCancer The link to the clinical trial for Cu67 has been removed. Twice.
@@DCGreenZone It's only a trial in Phase 1, nothing fancy so far.
@@FightingProstateCancer Phase 1 2A From what I see, and I watched the videos on how it works, Pluvicto hangs onto cells for hours, the double radio ligand Cu67 hangs on for days iirc. There are videos in here.
Está enfermedad es difícil con tratamiento imaginen aquellos que no lo tenemos Dios termina con el sufrimiento del pueblo cubano
It is unethical to recommend "curative pathways for treatment of advanced prostate cancer." Metastatic prostate cancer is not curable in over 99% of patients - it is a lethal disease. "Curative" should be replaced with the word "aggressive"