Your summary to this video summarises why I listen…& learn! It’s you’re balanced, undogmatic, open-minded approach, which is all about communicating & pushing forward the science…not simply a particular message.
@@nicknorwitzPhDI agree with Steve. That being said I think it’s time you upgrade your microphone. Please? My old ears have not yet been fixed with carnivore 😅
The question Nick always conveniently ignores on X. “Nick. Why do you spend so little time discussing LDL clearance? Presumably everyone on a lchf diet has high VLDL output. It seems like massive LDL receptor down regulation explains the syndrome much better.” Adding carbs stimulates insulin, which up regulates LDL receptors”
I don't ignore this question. I just answer it far too frequently. So how about I explain your question with more questions (1) refer me to any literature showing insulin could account for the magnitude of the effect we see (2a-b) how does insulin-induced up regulation of LDL explain the triad [beyond isolated LDL-C; re HDL-Cs in the 120s?! up from a baseline in to 50s/60s?] and/or (b) exercise-induced exaggerations in the triad. An LDLR-focused explanation is insufficient. Also, I don't see undereducated T1D with LDL of 450mg/dl that often... @@davidzip8841
Bro… please don’t stop making videos!! I soooo appreciate your wisdom and insight. You are a rock star in this space and most importantly a scholar of the highest quality!! Stay curious my friend!!!
No way! I removed fibre, plants, carbs, seafood, and poultry from my diet for a reason. This has been miraculous, and I'm not going to change it because of an unimportant lab value.
I'm not lean mass but my LDL way up and a very low carb diet. It seems like between the lines several of the solutions for getting the LDL back down sabotage the keto diet, especially fix it by adding carbs!, Sheeze. One doctor said stay low carb but avoid saturated fats. Low carb + avoiding saturated fats = a miserable diet. There's so much more to that fat story I'll not go into. I have a spreadsheet where I calculated the carb to fiber ratio. This video is reminding me to revisit that. Chia seeds at the top, must remember to always add to salad. Lily's Stevia chocolates, still too many carbs and hard to control consumption. Same with Pecans that I used to buy and eat a bit but too frustrating, portions to small so rely on broccoli, cauliflower, and spinach. There's no magic bullet. I feel the weight loss, end of high blood pressure, end of diabetes, fatty liver, higher HDL, lower triglycerides all together out way concerns about LDL. LDL a long complicated story as to other reasons I wouldn't worry about it if my Dr. would stop making me doubt my own research.
You doctor has to say that or they could lose their licence. Also, you've researched it, your doctor likely hasn't, they are just parroting what the pharmaceutical industry told them (many medical schools take their funding from the pharmaceutical industry so it starts early in their career). I agree though, it is difficult. I eventually got to the point where I figured even if they could guarantee I would live 10 yrs less, the improvement in my quality of life from following this diet was worth it. After that it doesn't matter what they say.
Can't agree more when the world is not clear about the significance of high LDL. I also feel helpless. Adding net 100g net carb means >> 100g of total carb especially for low GI food. Does this mean abandoning keto or carnivore ? I feel like victim of the insuffiency in the health profession.
Sounds like you use keto for weight loss and the benefits that go along with weight loss. So you don’t need to be in ketosis for your health. Adopting a high fibre Mediterranean diet would give you the same advantage regarding avoiding sugar and processed foods and keep your lipids in the normal range. Nick has a Mediterranean recipe book if you want to try. I recommend.
I agree with your thought process. My LDL is 265. I am currently Keto. My Dr has had the conversation that "I am going to die before I hit 60, if I don't get it down.". She doesn't want to hear about how I've lost 80 lb, lowered my A1c, lowered my BP. My HDL and Triglycerides are within range. Jeez.
Hey, thanks for this. My husband’s doc is always freaking over his LDL. After reading your Oreo cookie experiment, and being well versed in the lipid energy hypothesis, I asked my husband if he wanted to game the next tests so his doc would be less concerned. We will implement some of these 2 weeks before his blood tests. He is not quite LMHR, but almost. Keto/low carb since 2018, lost weight, got rid of metabolic syndrome and feel the energy of good health.
LOVE your practical videos ! I'm LMHR and have gone on a statin (40 mg Rosuvistatin) after a years of 2 of fighting with my cardiologist. (family history fatal MI in a parent at age 51) and for the month before going on the statin, I tried the half a sweet potato and did a recheck of the lipids. They were exactly the same as before making that change. I have BMI 20.5, 62 yo female, runner, cyclist, yogi, use a strength trainer 2x a week for 1.5 years and am on HRT (including testosterone). My eating window is generally 6-8 hrs. I'm also on low dose amlodipine (2.5 mg) for mild hypertension (and Raynaud's syndrome, which the calcium channel blocker has helped symptoms). I am watching and waiting for some results of the LMHR study which is underway. My coronary calcium CT test 2 years ago was zero. I know the statin is not a settled issue and have chosen to go on it with much thought. I have no noted side effects from the statin and I take CoQ10 to possibly mitigate the muscle side effects. I ordered the mac bundle as well as the chocolates (I subscribe to the chocolate almond bars already but am going to try the ginger 95%) Thanks. I am very curious how long the added carbs would take to see a change in LDL. I have been keto since 2011. I understand this is not medical advise.
thank you Nick - this video is wonderful. I love that you are giving folks the information and not telling them what to do. Experiment on yourself. I also "love" that you are able to bring folks together and that they can agree on the data. Love the document. I am a LMHR
This is exactly in line with my experience. If you are fit, healthy and active, doing IF etc but your LDL is too high, gain some body fat, limit activity, go to bad with full stomach and after few days your LDL will improve. Overall health will deteriorate. This should be treated as best evidence that something is fundamentally wrong with traditional guidelines on lipids.
Thank you so much for your response. I’m 74 and have been eating a very low carb, no sugar diet for decades and for decades my doctor has been insisting I take statins. He continually says I should have had a heart attack years ago. Berates me but I have not given in. As a matter of fact the lower I take my carbohydrates the higher my ldl goes. My In Body overall score is .386. I’m in good shape but he just doesn’t see it or he’s in a cognitive dissonance. The cholesterol hype really must be put to rest. Thanks again.
@@thehappyfellow5500 THis wont work. I eat lower calories and no carbs and my LDL went up like most people. It was when I Ate MORE. Mainly eggs, liver and fish that my ldl went down. If you get enough HDL it will carry it through your body and help it pass . That's how you lower LDL. Your body needs cholesterol and will produce it anyways however it goes into Hyperdrive when you avoid it altogether and triples output.
Yea, I'm of the belief that LDL is a benefit in the context of keto, which is scarcity in nature. It's part of the immune system, which makes sense if you're hunting and scavenging. I suspect it might play a role in longevity, too, at least for me. I come from centenarians. My LDL has always been high. And when I was vegan and lowered it just 22 points, my memory turned to shite. It went back to normal with animal foods in four days. Humans think they know stuff...sorry...nature will beat us every, single, time.
Hi Nick, this has been the best UA-cam video I’ve ever seen explaining this. I have been low carb since 2019 and my lipid levels have doubled since going low carb and more saturated fats. I was on 40mg of Simvastatin from 2008-2018 and stopped taking from all the problems I heard about them. My levels were pretty much kept in check with the statin and eating a SAD diet. I’m 60 now but have eaten the SAD diet for all my life, with being pre diabetic range for the last 25-30 years or maybe even more. I just had my last labs done about a week ago and finally decided to go on a low dose, 10mg. of Crestor and doc will retest in 2 months. In the meantime, I am cutting back on saturated fats and adding in more fiber, since being on keto I was eating very little. I also started lifting weights and I do walk most days of the week. Last night I ate a mix of smoked salmon and sardines with some roasted red peppers and this morning my blood sugar reading was 86. Usually it’s around 95-105 with low carb diet. Today, I lifted weights and an hour later my blood sugar was 90, haven’t seen this number early in the afternoon, it usually comes down in 80’s and 90’s at night. So I hope eating more of a Mediterranean diet and weight lifting helps my insulin sensitivity and my lipid profile because as you’ve mentioned in your video, that high fat low carb might not work for some people. You made me a subscriber!!😊😊😊
Why should we micromanage our cholesterol and LDL levels? Doesn't our genes and our bodies do that for us based on our physiologic needs? I could see doing this short term to pass a physical for a job or to get insurance. Just because you can lower these values, doesnt mean you should. Also, be aware that foods you have recommended to lower LDL such as sweet potatoes, tahini, and chocolate are very high in oxalates. Oxalates prevent the absorption of minerals and accumulate in all the tissues of the body causing arthritis, osteopenia, anemia, fibromyalgia, bladder pain, urinary stones, etc.
I really appreciate your channel. I know you are going against what I call the cathedral of modern medicine, so I really admire your courage. I went keto to help with my mood and ended up being a full-blown exercise addict. Your insights are a tremendous help on my journey. I'm really hoping you get the following you deserve. Just don't give up because of low follower count... please.
Being a T1D and an a LMHR it is difficult to find the solution. No carb way of eating stabilised my blood sugars and lowered my A1c to 4,8% for the last three years.
Thank you for being objective in your gradual journey and desire to seek out the truth. Bright individuals like yourself aren't interested in dogma and tribalism, rather you are interested in the learning journey itself, no matter where it leads.
Too many comments on here from people that know very little about lipoproteins, but passionately parrot their favorite influencer lines. I doubt many of the commenters are medical doctors or PhD holders in a relevant field. Keep up the good work and wishing you success in your future medical career.
Thanks for the video and handout! I was really glad to hear that Keto burns PUFA preferentially, I saw a couple papers on it tonight. I've been looking for ways to burn PUFA stores. Was also glad you mentioned chia and flax, something I mentioned in a comment earlier this week. It is very nice that you often read and respond to comments here. Very informative, keep up the great work! Personally I'm aiming to avoid processed seed oils and high Omega 6 foods. I blame PUFA consumption for weight loss stalls I've experienced and for regaining some weight back on keto several years ago. Glad to be back on keto now but I'm intending to balance my omega ratio and reduce seed oils this time.
ive been on keto for 4 years now. never felt better. but a couple years ago i went to thailand and had a physical from some of the best doctors in the country. my LDL came back as like 400. it was really alarming for them. I was never really that over weight, but i did keto cuz it helped with a lot of different issues i was getting. it cleared up my skin and helped my breathing. I use to think i had asthma, but i later found out it was just me spiking my blood sugar. Nowaday, in my mid 30s, i feel better than i ever have. Im a big tennis player so cardiovascular performance is really important to me. I can tell when im keto, my energy levels are more stable and i can get full breaths of air. Im never out of breath when exercising. But seeing my LDL so high, the doctor basically told me to stop keto once ive "lost the weight" . Its hard to know what right because i feel and look good, but the "professionals" are saying to stop. Also, i basically do everything mentioned in this video already. I eat soluable and insoluable fiber. I have a large bowl of mixed salad everyday (like 72oz worth). I make my own dressing with extra virgin olive oil. I only cook with avacado oil. Eat macadamia nuts, lean on fish or lean cuts of meat. I eat almost a psychopathically clean diet. One thing to note, when i took the blood test in Thailand, I was told to not eat for 10 hours and not even drink water. This is unheard of and I wonder if something was lost in translation. When my blood work came back, they said i was dehydrated (and to drink more water) and my ketone levels were really high. At that point i probably had been fasting from food and water for over 12 hours cuz its hard to plan a perfect 10 hour fast. i suspect that being in such a fasted state with high ketone might have to do with my elevated LDL levels. I also had lots of quale eggs and salad the night before. These days, im trying not to be so strict keto, it seems to me just adding carbs allows ur LDL levels to come down. But as a result im not as lean as i was and my skin kinda breaks out time to time now. Its a little unfortunate, but im trying to play my odds and not completely discredit what the doctors are saying. Also if i do have carbs, i try to pick healthier choices. No high processed carbs. Il lean onto things like chickpeas /whole foods. Ive been meaning to get my blood work checked again. bet my LDL will look better now, but at what cost.
Find yourself a cardiovascular risk calculator. Put in all your metrics as they were and see what risk their is. Then put in the same metrics but with your LDL in a 'healthy' range. Finally put in the original metrics with high LDL but with your original higher weight. You might be surprised to see how little lowering your LDL reduces your risk of heart attack, compared to reducing your weight, given all the dire warning from doctors,, as in by their own calculators it may be a net benefit. They you can decide if that small increased risk of heart attack (not death, heart attack) is worth the increased quality of life following the diet. For me reducing my LDL to normal would reduce my risk of heart attach by 0.1% over 10 yrs. That's not high enough to stop the diet given the benefits I see. The fact that I have bipolar and migraine increased my risk by 1.1% (they were options on the one I used). Keto effectively manage my bipolar without medication and to a lesser extent the migraine, so seems like keto overall reduces my risk of heart disease by about 1% over 10 yrs all tings considered. Then there is also the fact that psychiatric medication causes diabetes that would massively bump up my risk much more than even just having bipolar and migraine, so it probably actually drops my risk further given if I wasn't following the diet I would need medication .
@@mimiverschueren4683 qrisk it's UK based, it uses postcode to calculate the risk, but that is optional and if you're in a country similar to the UK it'll probably still give you an idea.
I had a blood panel done a few years back while I was losing weight in ketosis. Same advice. Arrive fasted overnight. They do it to measure morning blood sugar but of course it will raise your LDL regardless of your diet. Mine was super high and I have never tested that high before. In fact they used to say my cholesterol was good. My best results were on a high fibre diet.
Who do you suggest? I've offered to "discuss" LMHR (or debate) with Attia, Layne, Dayspring... none have accepted. But I do enjoy a good 'exchange of ideas'
@@baccaratfitness2360 " If ldl particles stay around too long they can become oxidized and glycated which makes them inflammatory which can cause atherosclerosis. " That is one of the many mechanisms how atherosclerosis comes to be. But already the state in which LDL particles stay around very long is a symptom of metabolical dysfunction. And that metabolical dysfunction is causal for the other mechamisms which cause atherosclerosis / prevent the healing of the arteries. So the metabolic dysfunction MUST be the target, not a symptom thereof...
@@btudrus No, LDL particles can stay around if someone has familial hypercholesterolemia too because their liver has either fewer LDL particle receptors or Dysfunctional ones that are unable to remove them from the blood. Listen to Chris Masterjohn’s podcast on living with h-FH (heterozygous familial hypercholesterolemia). Since my heart attack I’ve been looking for and researching information on this and there isn’t a lot out there but his understanding is thorough and helpful. Would you consider me to be metabolically unhealthy if I’m lean, muscular and have triglycerides in the 50’s, HDL around 70 fasting insulin at 5? FH is a genetic disorder. Masterjohn’s in depth analysis explains the role of insulin signaling, stress response, pcsk9 inhibitors and much more.
This is invaluable information for someone who's trying to get LDL in check while being on strict keto. Especially the fiber part, given the well-known benefits of it. A while ago I also checked if switching from metal to paper coffee filters would have any impact on my LDL, and it kinda did, not dramatically though.
Man when adding Oreos, decreasing your activity and gaining weight are a Doctor's recommendation for lowering cholesterol, something's gotta be fucked with our understanding of cholesterol....
Almost seems like he's trying to navigate his own bias about keto being superior, trying to solve issues he created first. Be keto! But also eat oreos, they're not Keto but something about oreos is helping... i wonder what it might be...
There is healthy LDL ( big fluffy particles) and unhealthy LDL (small particles). No point in having low LDL if it's healthy. With keto or LCHF you don't need to watch your LDL, your body is making it as much as it needs to. We are different and have different LDL numbers, there is no one number to apply to everyone.
Thanks Dr Nick! A couple of thoughts post-video: The fact that LDL-c (and other parameters) are so labile makes a mockery of the idea that you can predict anything (like mortality from heart disease) from 1 measurement of a labile biomarker. Likewise: that the numbers can be manipulated through dietary hacks. So I am a LMHR and my LDL-c would give the average cardiologist an event. However, all my other numbers are wonderful, and if I really wanted to game the system, I could consume a 100g of carbs for a week or 2, back off the exericse at the same time, and eat more often, prior to my next blood test. But .... why bother? I treasure nutritional ketosis. For me personally, it is not worth trying to keep statin-obsessed doctors happy.
Actionable tools, my man 👊 As an ex keto guy, i appreciate this info. I've changed to Hubermans advice on a omnivore type diet. I originally used keto for the mental benefits, and i can testify that it does provide mental clarity, and i only did it for 6 months, following Dr Bergs version of healthy keto. I turned away after realising my strength was degrading, and so ive borrowed a mixture of both, using IF and organic whole foods to arrive at a omnivore diet. Im hoping that with healthy nutrition, exercise (hubermans protocols; cold/heat therapy, strength & cardio training etc) and a job that requires i move around all day, averaging 15k steps a day, im hoping that gives me the benefit of a long and healthy lifespan. Attia had me worried about LDL, so im focusing on high VO2 training to offset any LDL effects from nutrition. If my matrix for healthy living makes sense, let me know what you think i should do as an omnivore guy to make it better 👊😎
"strength & cardio training etc and a job that requires i move around all day, averaging 15k steps a day" sounds pretty great to me... I'm jealous ;) ... except you can keep your cold shower... I will never! ;)
@@nicknorwitzPhD cold showers i do twice a week, great when you need a shot of adrenaline. Sux to think about, but great once youve done it a few times. I do an ice bath after a 2hr run once a week. It took me three weeks to get comfortable with the idea of regular cold therapy, really does help to have Huberman walk through the required mindset to make it work, otherwise, id agree with you.
@@scotchbarrel4429Berg is a con. His version of keto is not healthy, it helps him sell supplements. Anthony Chaffee MD has the best dietary advice on UA-cam.
Thankyou . I watched this again .and understand it better . I would love to see a vidio on the oils and fatts you use and why and how . Thankyou for all you do and share with us .
From the lay person research I have done into LDL related to metabolism and cardiovascular health, I am no longer convinced that high LDL is necessarily a danger. Especially since I am lean and healthy. I believe there's still so much about LDL we don't fully understand that it could be more dangerous to go messing around with than not when it does not seem to negatively impact people without cardiovascular inflammation.
Thank you so much Reading the comments, I realized I did not give you credit or thanks for the handout & for even presenting these videos to help inform the masses. Luckily there are more professionals coming out every day & going directly to the people.
Great job Nicholas! Thank you so much for your explanation. I am a nutritionist from Portugal and like to "play" with keto/ Carb cycling. That said, i have been really enjoying your videos and your very open minded aproach and style. Justo one thing, what about raw avocado? I love chocolate as well but avocado is just fiber and essencially MUFAs.
I’ve been on Keto for 6 years now. I lost 150lbs and it’s a good thing - I required an Aortic Valve replacement 2 years ago. My coronary arteries are all clean though. I required a heart catheterization before my open heart surgery. My lipids on Keto are: Total Cholesterol=186, Triglycerides=46, HDL=62, LDL=115, VLDL=9
@akunamatata4266 aortic valve is a common need for surgical replacement due to birth defects such as bicuspid valve. The heart arteries are clear and the rest of the heart is fine outside of the common bicuspid birth abnormality.
Please do a video on people with suspected familial hyper cholesterolemia. I used keto to basically save my life from multiple auto immune diseases. I completely recovered. Fast forward… With a cholesterol of 380, small, particle sizes, high levels of apob.... unfortunately, I am not a lien mass hyper responder… As my triglycerides seem to go up with my cholesterol. As a result, I am revisiting a pescatarian diet via orders by my Functional Medicine physician. Hoping I do not run into trouble reintroducing beans, and some gluten-free grains like wild rice and quinoa into my diet.
I really appreciate how you are not afraid to name the issue of physician and patient concern about high LDL on keto. I’m really hoping that high LDL on keto does not have the same damaging effect as high LDL on a mixed diet. Hopefully that information is coming soon.
the problem there is keto is that is not really a well defined diet. Lets say that the only thing that matter is LDL oxidation, then there isnt a strong reason why the fiber-extreme region of keto wouldn't cause the same, as you are eating a lot of thing that could mess with pOx balance, and the reduction in cholesterol could be as well a move to ketosis to glucose production, which is completely independent of LDL oxidation. depending on age, the carnivore-extreme of keto (the so called ketovore) could also be unsafe because of unknown long term effects of the past diets that could affect permanently the capability/functionality of endogenous Redox buffering in the system. the second part is more unlikely, but it is still a possibility. Also keto is a medium to deficient protein diet (as softly inhibits ketosis), so the likelihood of full glutathione production/uric acid is quiet dependent in the protein choices, if it is even possible to reach full glutathione production in a medium protein diet.
If you're doctor is worrying you before you decide what to do make sure you understand the magnitudes of the risk you are dealing with. Find a cardiovascular risk calculator online that includes some of the things you have under control using the diet if relevant (in the UK qrisk is a validated option). Put in your metrics as they are now. Then answer the questions again with the LDL in a normal range and see what the difference is. For me 0.1%, over 10 yrs risk of heart attack. There is no way I am taking a statin, and that risk isn't worth giving up the benefits I've experienced (I need to be in ketosis to get those benefits and I don't do well with plant oils even the good ones). It's also on a par with my risk of dying in a RTA in the same time frame given the mileage I travel and I'm not planning on stopping travelling to work either. If you've seen a benefit from the diet such as weight loss, also try putting in you're metrics with your original weight and lower LDL (because that's where your going back to if you give up the diet) and see what your risk would be then. For me the ketogenic diet is definitely a net benefit in terms of my risk of heart disease (overall 8.7% risk prior to diet vs 1.4% risk after). Doctors focus too much on LDL but that isn't the only risk factor for heart disease and the ketogenic diet improves may of the others.
Since Dr. Cromwell is a collaborator, let’s hear what he says about ApoB. “1. ApoB lipoproteins are a causal component in the development of atherosclerosis. 2. The risk posed by ApoB is a function of quantity over time. The higher the ApoB and the longer the high ApoB exists, the greater the ASCVD risk. 3. In the absence of data to the contrary, it is presumptively unhealthy for ApoB to remain high for extended periods in most physiologic states. 4. The ASCVD risk of high ApoB over short periods differs from that of high ApoB over long periods.”
Ad 1. Causal component doesn't mean neither "necessary" nor "sufficient". Ad. 2. That is simply not true. Ad. 3. There is already evidence to contrary. Ad. 4. So what?
@_________9996it’s a Cleveland clinic study vilifying 4PY…a metabolite of niacin. The study has some holes in it, and is unconvincing. Check out Dr. Ford Brewer’s take on it.
I'm a LMHR doing a therapeutic Keto Diet and can't and won't go back to carbs. Just finished a 30 days water fast. I used to have a high LDL. Had a blood panel done days after the water fast. My LDL is now in the 'healthy range'.
@@nicknorwitzPhD I did my own n=1 experiment too b4 your video came out. indeed from my own, 1) increased in carbs is a strong factor- 100-150g per day. 2) reduced in physical activity- cut from brisk walking 6-8km daily by half. 3) Increase intake of fiber basically from China seeds, flaxseed meal and psyllium husk. 4) didnt test increase in weight, as I am T2D and have hard time putting on weight n was one of the reason i switch out from strict keto. 5) Fasting- the last meal and first meal gap ranges from 15-19hrs , not sure how it impact LdL. 6) I did have morning fasting blood ketones of 0.5mmol. Question regarding fiber, is the effect from fiber or from the plant sterol which are also presence in most of them ?
Great vid. I added carbs. Ldl 270 to 130. Tahini is great. Try this for a dessert- Tahini, sesame seeds, low caeb sweetner, some chopped almonds. It's my go to dessert.
Since you now advertise for palmitoleic acid (16:1n-7), may we ask your opinion about the paper with DOI:10.1093/ajcn/nqab195, which found that people in the highest quintile of palmitoleic acid in the bloodstream had a lifespan an average of 6.62 years less than people in the lowest quintile? Cf. table 3. Thanks.
*When speaking of dietary fiber/ fibre, only its singular is used, as in "There are different kinds of dietary fiber." The plural, fibers/fibres is used only when speaking of component structures within larger structural or functional units, like muscle fibers, or woven plant fibers).* Every time you said, "Fibers," it sounded like you had gone off to talk about weaving or macramé.
keto has been around for over 100 years, epileptics who are non responders to medication have been on this diet for long enough to know- do they have a statistically higher propensity for heart disease?
The first sentence of the paper’s summary is: “Dietary fibers act through the microbiome to improve cardiovascular health and prevent metabolic disorders and cancer.” Does this statement presume the high LDL is bad for cardiovascular health and that by lowering LDL then cardiovascular health is improved? If one assumes that LDL isn’t universally negative regarding cardiovascular health, then the summary is at best only conditionally true.
Appreciate you Amy! And oddly haven't gotten trolled on that point yet. But they can enjoy the vision of my 1:1 erythrocyte n6-3 ratio while I enjoy coconut butter-tahini Halva!
I just read Toxic Superfoods, dark chocolate, almonds and spinach are amongst the highest in oxalate content and they are also some of the most common go tos in keto. White chocolate is safe and there are still plenty of alternatives for us
Cannot locate the one pager google document. I am on the edge of LMHR and making an LDL lowering experiment to show a lesson to my resident GP who is taught to abide by nothing but Framingham risk calculator.
Timely for me. I started keto because of a pre-diabetes diagnosis. Lifelong lean and running since I was 20. I’m 71 now. Cardiologist wants my LDL below 50 because I had a CAC of 120 in 2016. She’s increased my rosuvastatin from 10 to 20 mg. That lowered my LDL to 74. So now I’m taking 40 mg rosuvastatin. Spot checking my blood glucose leads me to believe that my next A1c will put me back in the pre-diabetes range. I added in 100-200 gm carbohydrates about a year ago. That put my LDL in the 80-100 range with the 10 mg rosuvastatin.
Instead of using a massive dose of statins, the latest approach is to combine a low-dose statin with ezetimibe. Much more effective with a lower chance of negative sides.
You sound like me, started keto (previously SAD) for an A1c of 5.8. On carnivore/keto (6 months) 6.0 A1c (but glycated albumin 13.3 not prediabetic) my CAC is 175 at 55. LDL extreme high. Very lean, will contemplate statins after trying “some carbs” for awhile. If I had a cac of 0 it would make my choice easy but for now, I’ll try a few hacks (maybe even a little carb and PUFA 😮).
@@brianshockley8161 I’ve been on rosuvastatin since 2016. I’ve had no side effects that I know about. I don’t like taking medication, even OTC. But, lots of heart disease on my father’s side of the family. Like you the CAC was the factor that made me decide to start a statin. PS - I’m getting another CAC next week. My PCP advised against it due to radiation exposure. But, I’m willing to take that risk just to know what’s been happening in the last 8 years.
Two questions: 1. What is the mechanism by which fibre lowers LDL? 2. How does increasing your weight via muscle vs. fat compare with respect to lowering LDL? On a surface level based on the LEM it would seem adding muscle is not helpful, as it just increases your energy demands and thus the need to ship fats around.
Tahini-wise: Pro tip from famed chef, Michael Solomonov: first, macerate the chopped garlic in the lemon juice. The longer, the less sharp the garlic flavor.
Is LDL level of any significance at all at least in the setting of a low BMI and an HDL level of > 60 together with a TG/HDL ratio of < 1.5 or even better 1 or less. LMHRs (Lean Mass Hyper-responders) are an arbitrary but useful construct? I am a retired physician and Nick Norwitz, PhD, Ben Bikman PhD, and Dr. Paul Mason are some of my favorite medical gurus. I am 80 years old. On a ketogenic diet over 23 months my TG/HDL ratio is markedly decreased, My HDL has increased from 42 to 60. My TGs are down. from 100 to 150 to 60-75. My weight has decreased from 195 to 160 over the same period. But my LDL has increased to 130. I have some skepticism about whether LDL is really much of a factor in causing heart disease. Assuredly BMI, Insulin Resistance, Diabetes, and Hypertension are incredibly more important than LDL or even APO-B as related to one's developing heart disease! Dave Feldman and Nick Norwitz are heroes of mine. That being said, studies need to be done on a broad groups of people who are LHMRs! In my own case in 23 months, I have managed to get off Amlodipine for hypertension, and off Metformin for Diabetes. I stopped my statin 3 years ago because statins increase the risk of Diabetes and because of my increasing skepticism that that there was any net positive benefit to harm ratio. I eat no "seed oils" at all. They were unknown before about 1900 and beyond that because they are PUFAs and have multiple double bonds, they are often oxidized in the bottle before being ingested. I quit takin fish oil after reading that > than 60% of brands tested were proven to be rancid ie oxidized. I, like Nick, do not think everybody needs a ketogenic diet. But over many years, I became a carbohydrate addict to the point that I must avoid sugar and even fruit, If I buy a quart of blueberries, I will eat them all within an hour. I hope this long post helps at least one other person!
No oreo toxic cookies for me🤮🤮🤮 And here in America they spray with pestesides all fruits and veggies🤮. That's why i use to have cramps, and gut issues before. For 2 years now i do lion/ omad, at 52❤ and i feel like 22❤.
The veggies have their own defense toxins. That’s what is messing your guts up. Slow poisoning is still poisoning. They don’t want to be eaten by you. They can’t run. They taste like crap because you aren’t supposed to eat them.
@MariuszChr I expect that was a sarcastic comment. Keto Oreos would be low carb and thus not give the cholesterol lowering effect. Not sure why one would want to lower a transport molecule that your body is producing, IMO: to return damaged or used cholesterol to the liver to be broken down or filtered as necessary. I propose that a mixed diet doesn't contain enough cholesterol and the Randall Cycle prevents cells from absorbing the proper amount for cellular repair and proper autophagy.
Never had the Catalina Crunch rip off... can't imagine it's that good. www.iherb.com/pr/catalina-crunch-keto-friendly-sandwich-cookies-chocolate-vanilla-16-cookies-6-8-oz-193-g/107051?gad_source=1&gclid=CjwKCAiA_5WvBhBAEiwAZtCU7ySA1-N2pGJqjw59fPhFxc0wbSa3-nWB4ebwcAFoTWZ5olRfmT3KCBoCrx8QAvD_BwE
PS Your description of how to add a ketone level "buffer" in order to play with adding more carbohydrate containing foods is spot on, in my experience.
Hey Nich! Great video, sort of a lengthy question if you have the time. Ive been worried about the 3-6 ratio as my liver enzymes went real high increasing my fats from conventional beef, canned sardines etc. (had plenty of greens, I now buy organic) I've since switched to grassfed sources and started taking cod liver oil daily. I'm a very skinny guy and am not worried about getting any subcutaneous fat so I've since left ketosis with complex carb sources. Would having these 'healthy' omega 3 fat sources still cause a 'toxic' environment for my liver as Im not keeping my net carbs low? (High fat+high carbs inherently damaging to liver?) I am scared to have things like nuts and fruits now as well and I'm wondering where these fit into the mix for someone like me. Thank you for helping so many people with your content!
My HDL-C is always 80 or above, and my triglycerides are always 60 or below. My BMI is always less than 21. BP always less than 120/80. HOMA-IR less than 2. I recently asked my primary to prescribe a statin because I understand independent risk variables. Nick does not. That reduced my LDL-C to 79.
True, but almost everything he does is broadcast and amplified by his cohorts to stand for the proposition that elevated ApoB/LDL-C is not problematic, and that statins are useless when compared to Oreo cookies, and other such nonsense. And then he just stands idly by because he’s not saying this, Dave Feldman is the one spreading such nonsense. That hardly leaves him blameless.
Some people on ketogenic diets are pretty low BMI, so an increase in BMI would not necessarily be a bad thing. There is also such a thing as diminishing returns for health benefits gained from exercise, which is a nuance that could be applied here. He clearly gave an example of the changes he noticed in himself when putting muscle and just a little bit of fat. With the way you are commenting, just throwing out negative connotation with no logical points being made, it doesn't do anything productive. Perhaps be a little more open minded and you will see that the nuance in the discussion might be able to teach you something.@@davidzip8841
Hi sir just new to your channel... enjoying it but feel its all a bit over my head... Very interested in the one pager document but I'm not seeing in on the community page? I feel like if i could see this it might help me absorb and understand a bit better Thanks
This is fantastic! Thank you so much! LMHR here - LDL 311, HDL 118, TG 53, BMI 17! CAC score 0 !! Loved the other ideas for keto beyond carnivore! Are you ever looking for subjects for studies???
@@Iam-not-as-grumpy-as-Isound TY. what do you think is best way? Does he have an email? I wrote to Dave Feldman on the twitta :) but I suppose these folks don't read social media comments.
Does MCT oil or exogenous ketones lower LDL on keto? Based on my surface understanding of LEM it could., because more ketones means 1) less need for fat transport via LDL and 2) body consumes less glucose and thus if high LDL is triggered by depletion of glycogen, then the body consuming less glucose means glycogen gets less badly depleted -> less LDL
why do I need to lower the cholesterol mate? Many studies, the real ones I am referring to state exactly the opposite, I hope you read this comments, thanks
Isn't it that when you apply some/many of those LDL lowering measures, you do indeed see the decrease in LDL-C in your blood, but at the same time you see other lipid markers go in the "wrong" direction? Like higher triglycerides, lower HDL.
Thanks for the info. LMHR doing low carb and 16:8 IF, very lean with bmi around 16.5. I have to reduce my LDL to please my doctor so that she can stop pushing statins to me. Adding carbs does cause GI issues for me, but I will try your suggestion of adding MCT oil.
This is a really helpful video, thanks Nick! I'm a hyper-hyper-responder, so I'm keen to explore all my options - I also want to be prepared for the inevitable statin conversation when I see my doctor. I haven't been able to find the link for the google doc you mentioned though, has it been removed? Thanks again!
@nicknorwitzPhD Very! I'm spending the weekend down the LMHR rabbit hole and loving it 😁. Could you send me the Google doc link for the summary document you put together with Hill, Baker & Cromwell, I'd like to print it off. Thanks again!
@@kuna129 there is no mechanism how these could be good. also, every plant contains plant toxins which will contribute to chronic inflammation and thus to AX.
@@btudrus:) "plant toxins which will contribute to chronic inflammation and thus to AX" - doesn't make a lot of sense. AX is not a disease. AX is an abbreviation for Arabinoxylan, indigestible polysaccharide found in grains. Grains also contain starches, which are not keto-friendly. My Q was about using psyllium husks that have no starch as a source of AX. Fiber could cause problems for some people, similar to milk - some could drink gallons of milk with no ill effects, some would get intolerance to lactose or allergy to milk proteins. "there is no mechanism how these could be good" - someone misinformed you. Fiber is a good food source for the intestinal microflora, and healthy, diverse microflora is a large contributing factor for human health.
LEM really explains the elevation of LDL for lean individuals that need the liver to traffic fats for daily living metabolic needs. People who have more fat stores, or who are eating lots of carbs will not need the liver to traffic these fats, so don’t need the elevated LDL. If not LMHR, I’d be looking at insulin resistance as a major risk factor.
@@KeepingItReal321 But elevated LDL has always been flagged as the main culprit of CVD. Therefore, there must be a reason for high LDL other than Ketogenic+LMHR, right? And if LEM is a general model, it should explain high LDL in this other (much more common) context. And also, it should explain the lowering of LDL by all these other methods Nick is talking about. So, basically, what I'm asking is a clearer and detailed explanation of all these other methods and what does LEM has to do with them. And if LEM does not apply, explain why not and then present a more general model that do explains.
So you are really suggesting people to jump through all those hoops just to calm down your doctor, who might be worried about your LDL level, although you yourself know for a fact, that LDL has nothing to do with CVD or any other health issues? mmmkey. 🤨
We need to keep repeating that Keto is good for Diabetes Obesity Epilepsy Mental illness Addiction Cancer And as for LDL Logic dictates then if you go way up on your fat the molecules of transport that fat will increase... LDL
Nick- please slow down (yes I know I can select to do this), because closed-caption isn't getting your message correctly. When you said insoluble is the better choice it writes soluble. What else is it not getting right because of the speed in which you speak?
I wouldn’t trust automatic closed captions with any scientific content. ApoB is Applebees 😂. Just listen to the speech and turn up the volume and put at 0.75 if you want. Ty
Why would you want to lower your LDL given how important it is as the transporter of cholesterol, and cholesterol is like so fundamentally essentially important to life? Didn't your body manage your cholesterol strictly by itself? Didn't someone use Oreo to lower LDL?
I’m a classic case of lean body mass hyper responder. Tried the experiment with adding back carbs to lower my cholesterol. Two weeks eating sweet fruits. Nothing changed. How could it be?! Actually due to steroid abuse I have a lot of plaque built up in my coronary arteries. Of course, doctor insist on statins which I want to avoid. I thought adding back some proper carbs would be the solution, but it didn’t work unfortunately. Dr. Norwitz, could you please tell me what I’m doing wrong? I have only my glucose went up .
Your summary to this video summarises why I listen…& learn! It’s you’re balanced, undogmatic, open-minded approach, which is all about communicating & pushing forward the science…not simply a particular message.
I deeply appreciate this comment. Thank you.
@@nicknorwitzPhDI agree with Steve. That being said I think it’s time you upgrade your microphone. Please? My old ears have not yet been fixed with carnivore 😅
The question Nick always conveniently ignores on X.
“Nick. Why do you spend so little time discussing LDL clearance?
Presumably everyone on a lchf diet has high VLDL output.
It seems like massive LDL receptor down regulation explains the syndrome much better.”
Adding carbs stimulates insulin, which up regulates LDL receptors”
I don't ignore this question. I just answer it far too frequently. So how about I explain your question with more questions (1) refer me to any literature showing insulin could account for the magnitude of the effect we see (2a-b) how does insulin-induced up regulation of LDL explain the triad [beyond isolated LDL-C; re HDL-Cs in the 120s?! up from a baseline in to 50s/60s?] and/or (b) exercise-induced exaggerations in the triad. An LDLR-focused explanation is insufficient. Also, I don't see undereducated T1D with LDL of 450mg/dl that often... @@davidzip8841
@@nicknorwitzPhD Please explain in a video
Bro… please don’t stop making videos!! I soooo appreciate your wisdom and insight. You are a rock star in this space and most importantly a scholar of the highest quality!! Stay curious my friend!!!
No way!
I removed fibre, plants, carbs, seafood, and poultry from my diet for a reason.
This has been miraculous, and I'm not going to change it because of an unimportant lab value.
Congrats?
I'm not lean mass but my LDL way up and a very low carb diet. It seems like between the lines several of the solutions for getting the LDL back down sabotage the keto diet, especially fix it by adding carbs!, Sheeze. One doctor said stay low carb but avoid saturated fats. Low carb + avoiding saturated fats = a miserable diet. There's so much more to that fat story I'll not go into. I have a spreadsheet where I calculated the carb to fiber ratio. This video is reminding me to revisit that. Chia seeds at the top, must remember to always add to salad. Lily's Stevia chocolates, still too many carbs and hard to control consumption. Same with Pecans that I used to buy and eat a bit but too frustrating, portions to small so rely on broccoli, cauliflower, and spinach. There's no magic bullet. I feel the weight loss, end of high blood pressure, end of diabetes, fatty liver, higher HDL, lower triglycerides all together out way concerns about LDL. LDL a long complicated story as to other reasons I wouldn't worry about it if my Dr. would stop making me doubt my own research.
Just eat carnivore...it's simple and works great. Very little trash, food waste or excrement. Plants are what my food eats.
You doctor has to say that or they could lose their licence. Also, you've researched it, your doctor likely hasn't, they are just parroting what the pharmaceutical industry told them (many medical schools take their funding from the pharmaceutical industry so it starts early in their career). I agree though, it is difficult. I eventually got to the point where I figured even if they could guarantee I would live 10 yrs less, the improvement in my quality of life from following this diet was worth it. After that it doesn't matter what they say.
Can't agree more when the world is not clear about the significance of high LDL. I also feel helpless. Adding net 100g net carb means >> 100g of total carb especially for low GI food. Does this mean abandoning keto or carnivore ? I feel like victim of the insuffiency in the health profession.
Sounds like you use keto for weight loss and the benefits that go along with weight loss. So you don’t need to be in ketosis for your health. Adopting a high fibre Mediterranean diet would give you the same advantage regarding avoiding sugar and processed foods and keep your lipids in the normal range. Nick has a Mediterranean recipe book if you want to try. I recommend.
I agree with your thought process. My LDL is 265. I am currently Keto. My Dr has had the conversation that "I am going to die before I hit 60, if I don't get it down.". She doesn't want to hear about how I've lost 80 lb, lowered my A1c, lowered my BP. My HDL and Triglycerides are within range. Jeez.
Hey, thanks for this. My husband’s doc is always freaking over his LDL. After reading your Oreo cookie experiment, and being well versed in the lipid energy hypothesis, I asked my husband if he wanted to game the next tests so his doc would be less concerned. We will implement some of these 2 weeks before his blood tests. He is not quite LMHR, but almost. Keto/low carb since 2018, lost weight, got rid of metabolic syndrome and feel the energy of good health.
Let us know his results
If you manipulate the results you should educate your doctor not fool them.
LOVE your practical videos ! I'm LMHR and have gone on a statin (40 mg Rosuvistatin) after a years of 2 of fighting with my cardiologist. (family history fatal MI in a parent at age 51) and for the month before going on the statin, I tried the half a sweet potato and did a recheck of the lipids. They were exactly the same as before making that change. I have BMI 20.5, 62 yo female, runner, cyclist, yogi, use a strength trainer 2x a week for 1.5 years and am on HRT (including testosterone). My eating window is generally 6-8 hrs. I'm also on low dose amlodipine (2.5 mg) for mild hypertension (and Raynaud's syndrome, which the calcium channel blocker has helped symptoms). I am watching and waiting for some results of the LMHR study which is underway. My coronary calcium CT test 2 years ago was zero. I know the statin is not a settled issue and have chosen to go on it with much thought. I have no noted side effects from the statin and I take CoQ10 to possibly mitigate the muscle side effects. I ordered the mac bundle as well as the chocolates (I subscribe to the chocolate almond bars already but am going to try the ginger 95%) Thanks. I am very curious how long the added carbs would take to see a change in LDL. I have been keto since 2011. I understand this is not medical advise.
fasting insulin = 1.7
thank you for bringing rigorous study to diet. Sorely needed
thank you Nick - this video is wonderful. I love that you are giving folks the information and not telling them what to do. Experiment on yourself. I also "love" that you are able to bring folks together and that they can agree on the data. Love the document. I am a LMHR
hello....can you point me to the link for the how to at the end of his presentation? thnx if you are able, if not no worries
This is exactly in line with my experience. If you are fit, healthy and active, doing IF etc but your LDL is too high, gain some body fat, limit activity, go to bad with full stomach and after few days your LDL will improve. Overall health will deteriorate. This should be treated as best evidence that something is fundamentally wrong with traditional guidelines on lipids.
Or just eat a whole food diet with lower calories and have all the benefits with the low ldl.
Thank you so much for your response. I’m 74 and have been eating a very low carb, no sugar diet for decades and for decades my doctor has been insisting I take statins. He continually says I should have had a heart attack years ago. Berates me but I have not given in. As a matter of fact the lower I take my carbohydrates the higher my ldl goes. My In Body overall score is .386. I’m in good shape but he just doesn’t see it or he’s in a cognitive dissonance. The cholesterol hype really must be put to rest. Thanks again.
@@rumproast5159 Thank you for that.
❤🌹🦉🗝🎩
@@thehappyfellow5500 THis wont work. I eat lower calories and no carbs and my LDL went up like most people. It was when I Ate MORE. Mainly eggs, liver and fish that my ldl went down. If you get enough HDL it will carry it through your body and help it pass . That's how you lower LDL. Your body needs cholesterol and will produce it anyways however it goes into Hyperdrive when you avoid it altogether and triples output.
Yea, I'm of the belief that LDL is a benefit in the context of keto, which is scarcity in nature. It's part of the immune system, which makes sense if you're hunting and scavenging. I suspect it might play a role in longevity, too, at least for me. I come from centenarians. My LDL has always been high. And when I was vegan and lowered it just 22 points, my memory turned to shite. It went back to normal with animal foods in four days.
Humans think they know stuff...sorry...nature will beat us every, single, time.
Hi Nick, this has been the best UA-cam video I’ve ever seen explaining this. I have been low carb since 2019 and my lipid levels have doubled since going low carb and more saturated fats. I was on 40mg of Simvastatin from 2008-2018 and stopped taking from all the problems I heard about them. My levels were pretty much kept in check with the statin and eating a SAD diet. I’m 60 now but have eaten the SAD diet for all my life, with being pre diabetic range for the last 25-30 years or maybe even more. I just had my last labs done about a week ago and finally decided to go on a low dose, 10mg. of Crestor and doc will retest in 2 months.
In the meantime, I am cutting back on saturated fats and adding in more fiber, since being on keto I was eating very little. I also started lifting weights and I do walk most days of the week. Last night I ate a mix of smoked salmon and sardines with some roasted red peppers and this morning my blood sugar reading was 86. Usually it’s around 95-105 with low carb diet. Today, I lifted weights and an hour later my blood sugar was 90, haven’t seen this number early in the afternoon, it usually comes down in 80’s and 90’s at night.
So I hope eating more of a Mediterranean diet and weight lifting helps my insulin sensitivity and my lipid profile because as you’ve mentioned in your video, that high fat low carb might not work for some people.
You made me a subscriber!!😊😊😊
Cholesterol 431,ldl 315,trg49,hdl 100, it's ok
Why should we micromanage our cholesterol and LDL levels? Doesn't our genes and our bodies do that for us based on our physiologic needs?
I could see doing this short term to pass a physical for a job or to get insurance. Just because you can lower these values, doesnt mean you should.
Also, be aware that foods you have recommended to lower LDL such as sweet potatoes, tahini, and chocolate are very high in oxalates. Oxalates prevent the absorption of minerals and accumulate in all the tissues of the body causing arthritis, osteopenia, anemia, fibromyalgia, bladder pain, urinary stones, etc.
You are freaking brilliant!! So many gems here!! Thank you!
I really appreciate your channel. I know you are going against what I call the cathedral of modern medicine, so I really admire your courage. I went keto to help with my mood and ended up being a full-blown exercise addict. Your insights are a tremendous help on my journey. I'm really hoping you get the following you deserve. Just don't give up because of low follower count... please.
Appreciate it. Cheers :)
More videos like these on the benefits of eating certain foods. Great! Thanks, Nick.
Being a T1D and an a LMHR it is difficult to find the solution. No carb way of eating stabilised my blood sugars and lowered my A1c to 4,8% for the last three years.
Valter Longo Ph.D is curing T1D in mice, read his work.
That’s amazing. I assume that you are on insulin as well.
@@jamesdellaneve9005 Sure, I wouldn't survive without it.
How do you deal with your Endo & PCP with your high LDL? Do they suggest you take a station?
They can suggest. You dont have to take. Do Your research.
Thank you for being objective in your gradual journey and desire to seek out the truth. Bright individuals like yourself aren't interested in dogma and tribalism, rather you are interested in the learning journey itself, no matter where it leads.
Too many comments on here from people that know very little about lipoproteins, but passionately parrot their favorite influencer lines. I doubt many of the commenters are medical doctors or PhD holders in a relevant field.
Keep up the good work and wishing you success in your future medical career.
Thanks for the video and handout! I was really glad to hear that Keto burns PUFA preferentially, I saw a couple papers on it tonight. I've been looking for ways to burn PUFA stores. Was also glad you mentioned chia and flax, something I mentioned in a comment earlier this week. It is very nice that you often read and respond to comments here. Very informative, keep up the great work!
Personally I'm aiming to avoid processed seed oils and high Omega 6 foods. I blame PUFA consumption for weight loss stalls I've experienced and for regaining some weight back on keto several years ago. Glad to be back on keto now but I'm intending to balance my omega ratio and reduce seed oils this time.
Happy you're finding what works for you as an n = 1! That's always "the way!" Keep killing it and thanks for the engagement and $5 :). Means a lot.
Best supplemental fibers are psyllium seed husk and flaxseed, as well as beta-glucans
ive been on keto for 4 years now. never felt better. but a couple years ago i went to thailand and had a physical from some of the best doctors in the country. my LDL came back as like 400. it was really alarming for them. I was never really that over weight, but i did keto cuz it helped with a lot of different issues i was getting. it cleared up my skin and helped my breathing. I use to think i had asthma, but i later found out it was just me spiking my blood sugar. Nowaday, in my mid 30s, i feel better than i ever have. Im a big tennis player so cardiovascular performance is really important to me. I can tell when im keto, my energy levels are more stable and i can get full breaths of air. Im never out of breath when exercising. But seeing my LDL so high, the doctor basically told me to stop keto once ive "lost the weight" . Its hard to know what right because i feel and look good, but the "professionals" are saying to stop.
Also, i basically do everything mentioned in this video already. I eat soluable and insoluable fiber. I have a large bowl of mixed salad everyday (like 72oz worth). I make my own dressing with extra virgin olive oil. I only cook with avacado oil. Eat macadamia nuts, lean on fish or lean cuts of meat. I eat almost a psychopathically clean diet.
One thing to note, when i took the blood test in Thailand, I was told to not eat for 10 hours and not even drink water. This is unheard of and I wonder if something was lost in translation. When my blood work came back, they said i was dehydrated (and to drink more water) and my ketone levels were really high. At that point i probably had been fasting from food and water for over 12 hours cuz its hard to plan a perfect 10 hour fast. i suspect that being in such a fasted state with high ketone might have to do with my elevated LDL levels. I also had lots of quale eggs and salad the night before.
These days, im trying not to be so strict keto, it seems to me just adding carbs allows ur LDL levels to come down. But as a result im not as lean as i was and my skin kinda breaks out time to time now. Its a little unfortunate, but im trying to play my odds and not completely discredit what the doctors are saying. Also if i do have carbs, i try to pick healthier choices. No high processed carbs. Il lean onto things like chickpeas /whole foods.
Ive been meaning to get my blood work checked again. bet my LDL will look better now, but at what cost.
Find yourself a cardiovascular risk calculator. Put in all your metrics as they were and see what risk their is. Then put in the same metrics but with your LDL in a 'healthy' range. Finally put in the original metrics with high LDL but with your original higher weight. You might be surprised to see how little lowering your LDL reduces your risk of heart attack, compared to reducing your weight, given all the dire warning from doctors,, as in by their own calculators it may be a net benefit. They you can decide if that small increased risk of heart attack (not death, heart attack) is worth the increased quality of life following the diet. For me reducing my LDL to normal would reduce my risk of heart attach by 0.1% over 10 yrs. That's not high enough to stop the diet given the benefits I see.
The fact that I have bipolar and migraine increased my risk by 1.1% (they were options on the one I used). Keto effectively manage my bipolar without medication and to a lesser extent the migraine, so seems like keto overall reduces my risk of heart disease by about 1% over 10 yrs all tings considered. Then there is also the fact that psychiatric medication causes diabetes that would massively bump up my risk much more than even just having bipolar and migraine, so it probably actually drops my risk further given if I wasn't following the diet I would need medication .
@@sadtosuccessHi, just asking, what risk calculator(s) did you use?
@@mimiverschueren4683 qrisk it's UK based, it uses postcode to calculate the risk, but that is optional and if you're in a country similar to the UK it'll probably still give you an idea.
@@sadtosuccess Thxs for your quick reply!
I had a blood panel done a few years back while I was losing weight in ketosis. Same advice. Arrive fasted overnight. They do it to measure morning blood sugar but of course it will raise your LDL regardless of your diet. Mine was super high and I have never tested that high before. In fact they used to say my cholesterol was good. My best results were on a high fibre diet.
would be great to see you debating on other people's channels, I don't think anyone else understands the science like you do
Who do you suggest? I've offered to "discuss" LMHR (or debate) with Attia, Layne, Dayspring... none have accepted. But I do enjoy a good 'exchange of ideas'
Debate Bart Kay
Is there any reason to lower LDL other than to keep your doctor happy?
If ldl particles stay around too long they can become oxidized and glycated which makes them inflammatory which can cause atherosclerosis.
@@baccaratfitness2360 That is if the LDL is mostly type B particles and high TRG.
How does one lower apo-b?
@@baccaratfitness2360 " If ldl particles stay around too long they can become oxidized and glycated which makes them inflammatory which can cause atherosclerosis. "
That is one of the many mechanisms how atherosclerosis comes to be.
But already the state in which LDL particles stay around very long is a symptom of metabolical dysfunction. And that metabolical dysfunction is causal for the other mechamisms which cause atherosclerosis / prevent the healing of the arteries.
So the metabolic dysfunction MUST be the target, not a symptom thereof...
@@btudrus No, LDL particles can stay around if someone has familial hypercholesterolemia too because their liver has either fewer LDL particle receptors or Dysfunctional ones that are unable to remove them from the blood. Listen to Chris Masterjohn’s podcast on living with h-FH (heterozygous familial hypercholesterolemia). Since my heart attack I’ve been looking for and researching information on this and there isn’t a lot out there but his understanding is thorough and helpful. Would you consider me to be metabolically unhealthy if I’m lean, muscular and have triglycerides in the 50’s, HDL around 70 fasting insulin at 5? FH is a genetic disorder. Masterjohn’s in depth analysis explains the role of insulin signaling, stress response, pcsk9 inhibitors and much more.
This is invaluable information for someone who's trying to get LDL in check while being on strict keto. Especially the fiber part, given the well-known benefits of it. A while ago I also checked if switching from metal to paper coffee filters would have any impact on my LDL, and it kinda did, not dramatically though.
Good luck with having digestive problems and breathing problems and a bit of malabsorption and other ills with all those fibres and plant toxins.
Man when adding Oreos, decreasing your activity and gaining weight are a Doctor's recommendation for lowering cholesterol, something's gotta be fucked with our understanding of cholesterol....
Almost seems like he's trying to navigate his own bias about keto being superior, trying to solve issues he created first. Be keto! But also eat oreos, they're not Keto but something about oreos is helping... i wonder what it might be...
There is healthy LDL ( big fluffy particles) and unhealthy LDL (small particles). No point in having low LDL if it's healthy. With keto or LCHF you don't need to watch your LDL, your body is making it as much as it needs to. We are different and have different LDL numbers, there is no one number to apply to everyone.
Or fucked with Doctor's recommendations.
Totally love how you completely strawmanned and misrepresented all of the advice given here.
@@fowlerfitness592 I didn't do either of those things, but whatever helps you sleep at night.
Thanks Dr Nick! A couple of thoughts post-video: The fact that LDL-c (and other parameters) are so labile makes a mockery of the idea that you can predict anything (like mortality from heart disease) from 1 measurement of a labile biomarker. Likewise: that the numbers can be manipulated through dietary hacks. So I am a LMHR and my LDL-c would give the average cardiologist an event. However, all my other numbers are wonderful, and if I really wanted to game the system, I could consume a 100g of carbs for a week or 2, back off the exericse at the same time, and eat more often, prior to my next blood test.
But .... why bother? I treasure nutritional ketosis. For me personally, it is not worth trying to keep statin-obsessed doctors happy.
Actionable tools, my man 👊
As an ex keto guy, i appreciate this info. I've changed to Hubermans advice on a omnivore type diet.
I originally used keto for the mental benefits, and i can testify that it does provide mental clarity, and i only did it for 6 months, following Dr Bergs version of healthy keto. I turned away after realising my strength was degrading, and so ive borrowed a mixture of both, using IF and organic whole foods to arrive at a omnivore diet. Im hoping that with healthy nutrition, exercise (hubermans protocols; cold/heat therapy, strength & cardio training etc) and a job that requires i move around all day, averaging 15k steps a day, im hoping that gives me the benefit of a long and healthy lifespan. Attia had me worried about LDL, so im focusing on high VO2 training to offset any LDL effects from nutrition. If my matrix for healthy living makes sense, let me know what you think i should do as an omnivore guy to make it better 👊😎
"strength & cardio training etc and a job that requires i move around all day, averaging 15k steps a day" sounds pretty great to me... I'm jealous ;) ... except you can keep your cold shower... I will never! ;)
@@nicknorwitzPhD cold showers i do twice a week, great when you need a shot of adrenaline. Sux to think about, but great once youve done it a few times. I do an ice bath after a 2hr run once a week. It took me three weeks to get comfortable with the idea of regular cold therapy, really does help to have Huberman walk through the required mindset to make it work, otherwise, id agree with you.
@@scotchbarrel4429Berg is a con. His version of keto is not healthy, it helps him sell supplements. Anthony Chaffee MD has the best dietary advice on UA-cam.
Thankyou . I watched this again .and understand it better .
I would love to see a vidio on the oils and fatts you use and why and how .
Thankyou for all you do and share with us .
From the lay person research I have done into LDL related to metabolism and cardiovascular health, I am no longer convinced that high LDL is necessarily a danger. Especially since I am lean and healthy.
I believe there's still so much about LDL we don't fully understand that it could be more dangerous to go messing around with than not when it does not seem to negatively impact people without cardiovascular inflammation.
Thank you so much Reading the comments, I realized I did not give you credit or thanks for the handout & for even presenting these videos to help inform the masses. Luckily there are more professionals coming out every day & going directly to the people.
Great job Nicholas! Thank you so much for your explanation. I am a nutritionist from Portugal and like to "play" with keto/ Carb cycling. That said, i have been really enjoying your videos and your very open minded aproach and style.
Justo one thing, what about raw avocado? I love chocolate as well but avocado is just fiber and essencially MUFAs.
I’ve been on Keto for 6 years now. I lost 150lbs and it’s a good thing - I required an Aortic Valve replacement 2 years ago. My coronary arteries are all clean though. I required a heart catheterization before my open heart surgery. My lipids on Keto are: Total Cholesterol=186, Triglycerides=46, HDL=62, LDL=115, VLDL=9
Didn’t understand your heart was good but you needed surgery?
@akunamatata4266 aortic valve is a common need for surgical replacement due to birth defects such as bicuspid valve. The heart arteries are clear and the rest of the heart is fine outside of the common bicuspid birth abnormality.
How high is your LPa???
Please do a video on people with suspected familial hyper cholesterolemia.
I used keto to basically save my life from multiple auto immune diseases. I completely recovered.
Fast forward… With a cholesterol of 380, small, particle sizes, high levels of apob.... unfortunately, I am not a lien mass hyper responder… As my triglycerides seem to go up with my cholesterol.
As a result, I am revisiting a pescatarian diet via orders by my Functional Medicine physician. Hoping I do not run into trouble reintroducing beans, and some gluten-free grains like wild rice and quinoa into my diet.
I really appreciate how you are not afraid to name the issue of physician and patient concern about high LDL on keto. I’m really hoping that high LDL on keto does not have the same damaging effect as high LDL on a mixed diet. Hopefully that information is coming soon.
the problem there is keto is that is not really a well defined diet.
Lets say that the only thing that matter is LDL oxidation, then there isnt a strong reason why the fiber-extreme region of keto wouldn't cause the same, as you are eating a lot of thing that could mess with pOx balance, and the reduction in cholesterol could be as well a move to ketosis to glucose production, which is completely independent of LDL oxidation. depending on age, the carnivore-extreme of keto (the so called ketovore) could also be unsafe because of unknown long term effects of the past diets that could affect permanently the capability/functionality of endogenous Redox buffering in the system. the second part is more unlikely, but it is still a possibility.
Also keto is a medium to deficient protein diet (as softly inhibits ketosis), so the likelihood of full glutathione production/uric acid is quiet dependent in the protein choices, if it is even possible to reach full glutathione production in a medium protein diet.
If you're doctor is worrying you before you decide what to do make sure you understand the magnitudes of the risk you are dealing with. Find a cardiovascular risk calculator online that includes some of the things you have under control using the diet if relevant (in the UK qrisk is a validated option). Put in your metrics as they are now. Then answer the questions again with the LDL in a normal range and see what the difference is. For me 0.1%, over 10 yrs risk of heart attack. There is no way I am taking a statin, and that risk isn't worth giving up the benefits I've experienced (I need to be in ketosis to get those benefits and I don't do well with plant oils even the good ones). It's also on a par with my risk of dying in a RTA in the same time frame given the mileage I travel and I'm not planning on stopping travelling to work either.
If you've seen a benefit from the diet such as weight loss, also try putting in you're metrics with your original weight and lower LDL (because that's where your going back to if you give up the diet) and see what your risk would be then. For me the ketogenic diet is definitely a net benefit in terms of my risk of heart disease (overall 8.7% risk prior to diet vs 1.4% risk after). Doctors focus too much on LDL but that isn't the only risk factor for heart disease and the ketogenic diet improves may of the others.
Subscribed. Love Taza! I was eating Lindt 95% for a while until I read about the potential heavy metals and switched to Taza 95%.
It's great, right!?
Nice video Nick and as you say the information is to be used as a guide for those who may wish to use it, nothing more 👍
I want to live longer. Keeping my LDL. Thx Nick, really enjoy your analyses.
Nice, Nick! Leveling up the video production! Kudos!
Excellent content & great presentation style. fully appreciate the true science non-tribal approach!
Thanks! Appreciate this
Since Dr. Cromwell is a collaborator, let’s hear what he says about ApoB.
“1. ApoB lipoproteins are a causal component in the development of atherosclerosis.
2. The risk posed by ApoB is a function of quantity over time. The higher the ApoB and the longer the high ApoB exists, the greater the ASCVD risk.
3. In the absence of data to the contrary, it is presumptively unhealthy for ApoB to remain high for extended periods in most physiologic states.
4. The ASCVD risk of high ApoB over short periods differs from that of high ApoB over long periods.”
Can’t wait for PCSK9 inhibitors to become generic.
Ad 1. Causal component doesn't mean neither "necessary" nor "sufficient".
Ad. 2. That is simply not true.
Ad. 3. There is already evidence to contrary.
Ad. 4. So what?
@@btudrus Keeping your head in the sand I see.
@@ApoBeef "Keeping your head in the sand I see."
LOL, you are brainwashed by all that unscientific nonsense and reluctant to see the facts...
@@ApoBeef He's not wrong.
Regular release niacin 1000mg BID dropped mine significantly. Added bonus….it burns so good.
Niacin is bad for your liver and increases homocysteine. I prefer taking fish oil or krill oil.
@_________9996 I’ll check it out. Thank you for taking the time to post this.
@_________9996it’s a Cleveland clinic study vilifying 4PY…a metabolite of niacin. The study has some holes in it, and is unconvincing. Check out Dr. Ford Brewer’s take on it.
Super useful info, especially didn't know about PUFAs more readily converting to ketones than what SFAs do!
I'm a LMHR doing a therapeutic Keto Diet and can't and won't go back to carbs. Just finished a 30 days water fast. I used to have a high LDL. Had a blood panel done days after the water fast. My LDL is now in the 'healthy range'.
This is definitely a much better video compared to that Oreos , Keep up the good wok Nicholas- really well done 👍
not sure I agree, lol... but thanks for the kind words on this one ;)
@@nicknorwitzPhD I did my own n=1 experiment too b4 your video came out. indeed from my own, 1) increased in carbs is a strong factor- 100-150g per day. 2) reduced in physical activity- cut from brisk walking 6-8km daily by half. 3) Increase intake of fiber basically from China seeds, flaxseed meal and psyllium husk. 4) didnt test increase in weight, as I am T2D and have hard time putting on weight n was one of the reason i switch out from strict keto. 5) Fasting- the last meal and first meal gap ranges from 15-19hrs , not sure how it impact LdL. 6) I did have morning fasting blood ketones of 0.5mmol. Question regarding fiber, is the effect from fiber or from the plant sterol which are also presence in most of them ?
This is perfect for me. Thanks so much. I will do the lean-mass protocol. My LDL is super high.
Great vid.
I added carbs. Ldl 270 to 130.
Tahini is great. Try this for a dessert- Tahini, sesame seeds, low caeb sweetner, some chopped almonds. It's my go to dessert.
Since you now advertise for palmitoleic acid (16:1n-7), may we ask your opinion about the paper with DOI:10.1093/ajcn/nqab195, which found that people in the highest quintile of palmitoleic acid in the bloodstream had a lifespan an average of 6.62 years less than people in the lowest quintile? Cf. table 3. Thanks.
*When speaking of dietary fiber/ fibre, only its singular is used, as in "There are different kinds of dietary fiber." The plural, fibers/fibres is used only when speaking of component structures within larger structural or functional units, like muscle fibers, or woven plant fibers).* Every time you said, "Fibers," it sounded like you had gone off to talk about weaving or macramé.
I can't find the link to your one pager that is mentioned in the collaboration outtake section. Could you repost?
keto has been around for over 100 years, epileptics who are non responders to medication have been on this diet for long enough to know- do they have a statistically higher propensity for heart disease?
Excellent evidence based info.
Thanks!
The first sentence of the paper’s summary is: “Dietary fibers act through the microbiome to improve cardiovascular health and prevent metabolic disorders and cancer.”
Does this statement presume the high LDL is bad for cardiovascular health and that by lowering LDL then cardiovascular health is improved? If one assumes that LDL isn’t universally negative regarding cardiovascular health, then the summary is at best only conditionally true.
Cue the PUFA-phobes to come in and crucify you for the sesame oil. 🙄😉 Thanks so much for your work, Nick - we appreciate you!
Appreciate you Amy! And oddly haven't gotten trolled on that point yet. But they can enjoy the vision of my 1:1 erythrocyte n6-3 ratio while I enjoy coconut butter-tahini Halva!
I just read Toxic Superfoods, dark chocolate, almonds and spinach are amongst the highest in oxalate content and they are also some of the most common go tos in keto. White chocolate is safe and there are still plenty of alternatives for us
Where is the paper? Cannot locate
Cannot locate the one pager google document. I am on the edge of LMHR and making an LDL lowering experiment to show a lesson to my resident GP who is taught to abide by nothing but Framingham risk calculator.
Timely for me. I started keto because of a pre-diabetes diagnosis. Lifelong lean and running since I was 20. I’m 71 now. Cardiologist wants my LDL below 50 because I had a CAC of 120 in 2016. She’s increased my rosuvastatin from 10 to 20 mg. That lowered my LDL to 74. So now I’m taking 40 mg rosuvastatin. Spot checking my blood glucose leads me to believe that my next A1c will put me back in the pre-diabetes range.
I added in 100-200 gm carbohydrates about a year ago. That put my LDL in the 80-100 range with the 10 mg rosuvastatin.
Statins raise blood glucose. They are a double edged sword.
Instead of using a massive dose of statins, the latest approach is to combine a low-dose statin with ezetimibe. Much more effective with a lower chance of negative sides.
You sound like me, started keto (previously SAD) for an A1c of 5.8. On carnivore/keto (6 months) 6.0 A1c (but glycated albumin 13.3 not prediabetic) my CAC is 175 at 55. LDL extreme high. Very lean, will contemplate statins after trying “some carbs” for awhile. If I had a cac of 0 it would make my choice easy but for now, I’ll try a few hacks (maybe even a little carb and PUFA 😮).
@@brianshockley8161 I’ve been on rosuvastatin since 2016. I’ve had no side effects that I know about. I don’t like taking medication, even OTC. But, lots of heart disease on my father’s side of the family. Like you the CAC was the factor that made me decide to start a statin.
PS - I’m getting another CAC next week. My PCP advised against it due to radiation exposure. But, I’m willing to take that risk just to know what’s been happening in the last 8 years.
Great info I’ve been trying the fiber way since my walnut diet doesn’t work as well on low carb. And 100% dark chocolate.
Two questions: 1. What is the mechanism by which fibre lowers LDL? 2. How does increasing your weight via muscle vs. fat compare with respect to lowering LDL? On a surface level based on the LEM it would seem adding muscle is not helpful, as it just increases your energy demands and thus the need to ship fats around.
Tahini-wise:
Pro tip from famed chef, Michael Solomonov: first, macerate the chopped garlic in the lemon juice. The longer, the less sharp the garlic flavor.
Thanks for sharing
Is LDL level of any significance at all at least in the setting of a low BMI and an HDL level of > 60 together with a TG/HDL ratio of < 1.5 or even better 1 or less. LMHRs (Lean Mass Hyper-responders) are an arbitrary but useful construct? I am a retired physician and Nick Norwitz, PhD, Ben Bikman PhD, and Dr. Paul Mason are some of my favorite medical gurus. I am 80 years old. On a ketogenic diet over 23 months my TG/HDL ratio is markedly decreased, My HDL has increased from 42 to 60. My TGs are down. from 100 to 150 to 60-75. My weight has decreased from 195 to 160 over the same period. But my LDL has increased to 130. I have some skepticism about whether LDL is really much of a factor in causing heart disease. Assuredly BMI, Insulin Resistance, Diabetes, and Hypertension are incredibly more important than LDL or even APO-B as related to one's developing heart disease! Dave Feldman and Nick Norwitz are heroes of mine. That being said, studies need to be done on a broad groups of people who are LHMRs! In my own case in 23 months, I have managed to get off Amlodipine for hypertension, and off Metformin for Diabetes. I stopped my statin 3 years ago because statins increase the risk of Diabetes and because of my increasing skepticism that that there was any net positive benefit to harm ratio. I eat no "seed oils" at all. They were unknown before about 1900 and beyond that because they are PUFAs and have multiple double bonds, they are often oxidized in the bottle before being ingested. I quit takin fish oil after reading that > than 60% of brands tested were proven to be rancid ie oxidized. I, like Nick, do not think everybody needs a ketogenic diet. But over many years, I became a carbohydrate addict to the point that I must avoid sugar and even fruit, If I buy a quart of blueberries, I will eat them all within an hour. I hope this long post helps at least one other person!
Why should I lower LDL when higher LDL levels are found in centenarians?
No oreo toxic cookies for me🤮🤮🤮
And here in America they spray with pestesides all fruits and veggies🤮. That's why i use to have cramps, and gut issues before. For 2 years now i do lion/ omad, at 52❤ and i feel like 22❤.
My Stomach and Intestines have never been better after 4 months on Carnivore AND 75 LBS Lighter
Organic vegetables & fruits don’t have glyphosate & a lot less and not harmful pesticides.
@@aliciastanley5582 They Use Government Approved Organic Pesticides , GOOGLE IT
The veggies have their own defense toxins. That’s what is messing your guts up. Slow poisoning is still poisoning. They don’t want to be eaten by you. They can’t run. They taste like crap because you aren’t supposed to eat them.
@@akak5128 yeah that’s all I got and I don’t have any problems with the organic. If I eat in a restaurant I can taste the chemicals on salad.
Does Oreo make a Keto version of their product?
Don't do that. Any miracle keto variants of products are going to make your cravings super high, which will make you prone to overeating.
@MariuszChr I expect that was a sarcastic comment. Keto Oreos would be low carb and thus not give the cholesterol lowering effect.
Not sure why one would want to lower a transport molecule that your body is producing, IMO: to return damaged or used cholesterol to the liver to be broken down or filtered as necessary. I propose that a mixed diet doesn't contain enough cholesterol and the Randall Cycle prevents cells from absorbing the proper amount for cellular repair and proper autophagy.
@@MariuszChr Sarcasm.
Never had the Catalina Crunch rip off... can't imagine it's that good. www.iherb.com/pr/catalina-crunch-keto-friendly-sandwich-cookies-chocolate-vanilla-16-cookies-6-8-oz-193-g/107051?gad_source=1&gclid=CjwKCAiA_5WvBhBAEiwAZtCU7ySA1-N2pGJqjw59fPhFxc0wbSa3-nWB4ebwcAFoTWZ5olRfmT3KCBoCrx8QAvD_BwE
@@faisal-ca ok, it was highly plausible to be a serious question
This is so helpful Nick! Top notch info. Thank you.
PS Your description of how to add a ketone level "buffer" in order to play with adding more carbohydrate containing foods is spot on, in my experience.
Appreciate it!
Can’t find the 1 pager?
He’s correct on fish and seafood.
Hey Nich! Great video, sort of a lengthy question if you have the time.
Ive been worried about the 3-6 ratio as my liver enzymes went real high increasing my fats from conventional beef, canned sardines etc. (had plenty of greens, I now buy organic)
I've since switched to grassfed sources and started taking cod liver oil daily.
I'm a very skinny guy and am not worried about getting any subcutaneous fat so I've since left ketosis with complex carb sources. Would having these 'healthy' omega 3 fat sources still cause a 'toxic' environment for my liver as Im not keeping my net carbs low? (High fat+high carbs inherently damaging to liver?) I am scared to have things like nuts and fruits now as well and I'm wondering where these fit into the mix for someone like me. Thank you for helping so many people with your content!
Totally agree on the Macadamia! Best nut ever! Also for non-keto people. 🙂
You get it!!!
@@nicknorwitzPhD Yay!! 🙂 Btw, I like your cookbook. And no, I do not follow the Keto diet. But I recognize good food when I see it 🙂
How I long for condensed versions!
thank you for mentioning the lead and cadmium in chocolate, i will check out this taza bar
My HDL-C is always 80 or above, and my triglycerides are always 60 or below. My BMI is always less than 21. BP always less than 120/80. HOMA-IR less than 2. I recently asked my primary to prescribe a statin because I understand independent risk variables. Nick does not. That reduced my LDL-C to 79.
To be fair, Nick never says that apoB doesn’t matter. As much as his followers want him to.
@@byronfreemanDOExcept reducing LDL-C and apoB in itself causes no negatives in humans.
True, but almost everything he does is broadcast and amplified by his cohorts to stand for the proposition that elevated ApoB/LDL-C is not problematic, and that statins are useless when compared to Oreo cookies, and other such nonsense. And then he just stands idly by because he’s not saying this, Dave Feldman is the one spreading such nonsense. That hardly leaves him blameless.
His solution is to stop exercising and gain weight. Both two star solutions! Good Lord.
Some people on ketogenic diets are pretty low BMI, so an increase in BMI would not necessarily be a bad thing. There is also such a thing as diminishing returns for health benefits gained from exercise, which is a nuance that could be applied here. He clearly gave an example of the changes he noticed in himself when putting muscle and just a little bit of fat. With the way you are commenting, just throwing out negative connotation with no logical points being made, it doesn't do anything productive. Perhaps be a little more open minded and you will see that the nuance in the discussion might be able to teach you something.@@davidzip8841
Hi sir just new to your channel... enjoying it but feel its all a bit over my head... Very interested in the one pager document but I'm not seeing in on the community page? I feel like if i could see this it might help me absorb and understand a bit better
Thanks
I'm low-carb and pretty healthy and active. Why should I try to lower my LDL other than to make my doctor happy?
Nick, I think it's only fair to mention that both dark chocolate and sesame are extremely high in oxalates.
This is fantastic! Thank you so much! LMHR here - LDL 311, HDL 118, TG 53, BMI 17! CAC score 0 !! Loved the other ideas for keto beyond carnivore! Are you ever looking for subjects for studies???
They are. You should contact him.
@@Iam-not-as-grumpy-as-Isound TY. what do you think is best way? Does he have an email? I wrote to Dave Feldman on the twitta :) but I suppose these folks don't read social media comments.
Does MCT oil or exogenous ketones lower LDL on keto?
Based on my surface understanding of LEM it could., because more ketones means 1) less need for fat transport via LDL and 2) body consumes less glucose and thus if high LDL is triggered by depletion of glycogen, then the body consuming less glucose means glycogen gets less badly depleted -> less LDL
why do I need to lower the cholesterol mate? Many studies, the real ones I am referring to state exactly the opposite, I hope you read this comments, thanks
Asalamalaikum awesome video God bless for the wonderful information you shared brother.
So nice of you 😊
fascinating information!!!!
Glad you think so!
Isn't it that when you apply some/many of those LDL lowering measures, you do indeed see the decrease in LDL-C in your blood, but at the same time you see other lipid markers go in the "wrong" direction? Like higher triglycerides, lower HDL.
Thanks for the info. LMHR doing low carb and 16:8 IF, very lean with bmi around 16.5. I have to reduce my LDL to please my doctor so that she can stop pushing statins to me. Adding carbs does cause GI issues for me, but I will try your suggestion of adding MCT oil.
Great info, thnx. Please tell me where to download the 1 page paper, can´t find it anywhere 🤔
Great channel you have here! Glad I subbed!
Woot! Welcome welcome!
This is a really helpful video, thanks Nick! I'm a hyper-hyper-responder, so I'm keen to explore all my options - I also want to be prepared for the inevitable statin conversation when I see my doctor. I haven't been able to find the link for the google doc you mentioned though, has it been removed? Thanks again!
Glad it was helpful!
@nicknorwitzPhD Very! I'm spending the weekend down the LMHR rabbit hole and loving it 😁. Could you send me the Google doc link for the summary document you put together with Hill, Baker & Cromwell, I'd like to print it off. Thanks again!
Are psyllium husks good for AX?
no
@@btudrus:) Why?
@@kuna129 there is no mechanism how these could be good.
also, every plant contains plant toxins which will contribute to chronic inflammation and thus to AX.
@@btudrus:) "plant toxins which will contribute to chronic inflammation and thus to AX" - doesn't make a lot of sense. AX is not a disease. AX is an abbreviation for Arabinoxylan, indigestible polysaccharide found in grains. Grains also contain starches, which are not keto-friendly. My Q was about using psyllium husks that have no starch as a source of AX.
Fiber could cause problems for some people, similar to milk - some could drink gallons of milk with no ill effects, some would get intolerance to lactose or allergy to milk proteins.
"there is no mechanism how these could be good" - someone misinformed you. Fiber is a good food source for the intestinal microflora, and healthy, diverse microflora is a large contributing factor for human health.
Arabinoxylans, AX, not just beta glucans in barely, that’s new to me! love hearing about all these hacks, keep these videos coming, thanks!🙌💪
Can you explain the reduction of LDL using the LEM for all the cases you presented bedsides the LMHRs?
Less fatty acids needed and therefore less released from adipose and less packed into new ldl at the liver. So less LDL
LEM really explains the elevation of LDL for lean individuals that need the liver to traffic fats for daily living metabolic needs. People who have more fat stores, or who are eating lots of carbs will not need the liver to traffic these fats, so don’t need the elevated LDL. If not LMHR, I’d be looking at insulin resistance as a major risk factor.
@@KeepingItReal321 But elevated LDL has always been flagged as the main culprit of CVD. Therefore, there must be a reason for high LDL other than Ketogenic+LMHR, right? And if LEM is a general model, it should explain high LDL in this other (much more common) context. And also, it should explain the lowering of LDL by all these other methods Nick is talking about. So, basically, what I'm asking is a clearer and detailed explanation of all these other methods and what does LEM has to do with them. And if LEM does not apply, explain why not and then present a more general model that do explains.
Thanks Doc.
Why would you want to bring your LDL down?
So you are really suggesting people to jump through all those hoops just to calm down your doctor, who might be worried about your LDL level, although you yourself know for a fact, that LDL has nothing to do with CVD or any other health issues? mmmkey. 🤨
What link do we click to access the Google doc you mentioned at the end?
I love the content. Where is the one page google doc?
Thanks, Nick!
Why would a lean mass hyper responder what to lower their cholesterol? What are the long term effects if they don’t?
What are the long term effects if they do?
We need to keep repeating that
Keto is good for
Diabetes
Obesity
Epilepsy
Mental illness
Addiction
Cancer
And as for LDL
Logic dictates then if you go way up on your fat the molecules of transport that fat will increase... LDL
I do not see the link for house of macadamia
Why would you need to lower your LDL? The literature points to it actually increasing lifespan, not lowering it.
Nick- please slow down (yes I know I can select to do this), because closed-caption isn't getting your message correctly. When you said insoluble is the better choice it writes soluble. What else is it not getting right because of the speed in which you speak?
I wouldn’t trust automatic closed captions with any scientific content. ApoB is Applebees 😂. Just listen to the speech and turn up the volume and put at 0.75 if you want. Ty
Why would you want to lower your LDL given how important it is as the transporter of cholesterol, and cholesterol is like so fundamentally essentially important to life? Didn't your body manage your cholesterol strictly by itself? Didn't someone use Oreo to lower LDL?
I’m a classic case of lean body mass hyper responder. Tried the experiment with adding back carbs to lower my cholesterol. Two weeks eating sweet fruits. Nothing changed.
How could it be?!
Actually due to steroid abuse I have a lot of plaque built up in my coronary arteries. Of course, doctor insist on statins which I want to avoid. I thought adding back some proper carbs would be the solution, but it didn’t work unfortunately.
Dr. Norwitz, could you please tell me what I’m doing wrong?
I have only my glucose went up .