HRCT: Consolidation, Acute Lung Injury, and Organizing Pneumonia

In this talk, Dr. Seth Kligerman discusses CT findings related to consolidation, acute lung injury, and organizing pneumonia. The focus is on the fragility of normal alveolar wall histology, emphasizing the roles of type 1 and type 2 pneumocytes. Dr. Kligerman explores the response to lung injury, detailing the cascade from basement membrane damage to fibrosis, with organizing pneumonia being a common outcome. The talk covers various patterns observed in lung injuries, such as peribronchiolar consolidation, subpleural sparing, and reverse halo signs. Dr. Kligerman emphasizes the importance of understanding these patterns in diagnosing conditions like organizing pneumonia, which can arise from infections, inhalational injuries, drug reactions, and collagen vascular diseases. The presentation concludes with insights into the repair process and the potential progression to fibrosis in some cases.