Fantastic demonstration !🎉 A small typo: in any of first few slide where Negishi coupling mechanism has been shown, there after transmetallation it should take tosylate upon exchange not triflate. In short, it should be ZnBr(OTs) rather than ZnBr(OTf).
@@SimplifyingSynthesis no problem man. Oxydative addition can happen with a Pd II like in the Catellani Reaction for instance but it so rare that i got confused ;)
![Lp. Сердце Вселенной #60 РОЖДЕНИЕ ЛОЛОЛОШКИ [Финал] • Майнкрафт](http://i.ytimg.com/vi/YoR0pAV9FVQ/mqdefault.jpg)
respect your effort
Fantastic demonstration !🎉
A small typo: in any of first few slide where Negishi coupling mechanism has been shown, there after transmetallation it should take tosylate upon exchange not triflate. In short, it should be ZnBr(OTs) rather than ZnBr(OTf).
wtf how the hell paladium II is able to do an oxydative addition??!
Its not. My bad, I should have included activation of the complex to Pd(0)(PPh3)2
@@SimplifyingSynthesis no problem man. Oxydative addition can happen with a Pd II like in the Catellani Reaction for instance but it so rare that i got confused ;)
very interesting but try to make a more easy explication i m not a very good reaction mechanisms person and i need to see more arrows