Haemolytic Anaemia - classification (intravascular, extravascular), pathophysiology, investigations

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  • Опубліковано 10 лют 2025
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    "Haemolytic anaemia is defined as anaemia due to premature destruction of RBC. RBC also known as erythrocytes are produced in the bone marrow and then enter circulation to become mature. The mechanism of RBC haemolysis can be intravascular which means destruction of RBC within the vasculature or haemolysis can occur extravascularly. Which means haemolysis outside the vasculature typically in organs such as the spleen and liver where the reticuloendothelial system resides.
    Haemolysis stimulates the kidneys to produce EPO a hormone which stimulate erythropoesis the production of RBC. RBC are produced via the myeloid progenitor cell line to become erythrocytes in the bone marrow. Erythropoesis is also stimulated by other hormones including androgens and thyroid hormone."
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КОМЕНТАРІ • 133

  • @armandohasudungan
    @armandohasudungan  2 місяці тому +2

    🎥 DON'T JUST WATCH, LEARN ACTIVELY! TRY THE QUIZ! 🤓
    youmakr.ai/test-playground/questionnaire/673d394b859b9c170836ebff

  • @Allan.drummer
    @Allan.drummer 6 років тому +129

    Amazing! Best G6PD deficiency explanation yet. Short and sweet. How have you not won a noble prize for these drawings and explanations!?!

    • @SHOIBG10
      @SHOIBG10 3 роки тому +3

      He classed G6PD under intracapsular, extravascular. it is intracapsular but its a intravascular disease not extravascular!!!

  • @DrMpeliFM
    @DrMpeliFM 3 роки тому +3

    Thank you so much Osmosis! 😄, it's been 5 years in Med School🇹🇿. Never Felt so excited and got Hands on Medical Content to Learn, Thank you for that

  • @user-fx7pj3sk1r
    @user-fx7pj3sk1r 6 років тому +34

    The best physiology youtube channel - for medical science, veterinary science

  • @avjitsingh1404
    @avjitsingh1404 6 років тому +14

    Its an honor to have got some knowledge through your pictorial presentation. You are a real big help to lot of different students from different fields. Thanks alot Sir, God Bless you always!

    • @DentalClinician
      @DentalClinician 5 років тому +1

      ua-cam.com/play/PLT0nQuD9NwdlltAaSinDkdsTRUfBSob4l.html

  • @InsightfulScience
    @InsightfulScience 6 років тому +8

    Armando, you are so close to one million! You'll be there in under a week! Big congratulations my man!

  • @DocNaDer_2023
    @DocNaDer_2023 5 років тому +3

    best channel ever ! u saved my medical exams 😍

  • @pennylayne710
    @pennylayne710 5 років тому +12

    I would love to see the behind the scenes on this! Like how do you always have enough space!? Excellent videos. I've watched many in preparation for BOARDS. Thanks!

  • @Morlan-h4q
    @Morlan-h4q 7 місяців тому

    Armando , may God continue to bless you. Great medical content.

  • @abdullahalameer5557
    @abdullahalameer5557 Рік тому +1

    Amazing & astonishing… literally worths the 13 min!!! Thanks!👌

  • @mohammedsalahadin1680
    @mohammedsalahadin1680 2 роки тому

    I can’t stop thanking you, it was so helpful thanks dear❤❤❤

  • @user-tb4vx5kp1q
    @user-tb4vx5kp1q 4 роки тому +14

    Thank you so much, great explanation as always. I would like to note that the enzyme is called G6PD and the "D" stands for dehydrogenase not deficiency, so the correct name is "G6PD deficiency". Thanks again!

  • @joycezhang3966
    @joycezhang3966 2 роки тому

    Thanks!

  • @CynBH
    @CynBH 6 років тому +1

    I've had one dog and one cat killed by autoimmune hemolytic anemia. Until my shepherd mix got it, I had never heard of it. Ten years later when our cat was diagnosed, I was devastated. My dog's disease progressed slowly, so he actually died from the anemia. The cat's disease progressed so rapidly that she actually went into liver failure from the sharp increase in bilirubin.

  • @leodash5835
    @leodash5835 5 років тому +1

    Its really magical how you explain this and it gets so easy man you are my hero

  • @fasamah.kollie8767
    @fasamah.kollie8767 2 роки тому

    Greats 🤝it’s worth my appreciation. The foundation is builded.

  • @DrAdnan
    @DrAdnan 6 років тому +6

    Watching these along with sketchy is gold 👏

    • @itsfootballnotsoccer6140
      @itsfootballnotsoccer6140 Рік тому

      woah thanks for the recommendation mate ..i know I'm 4 years late but you've helped a fellow student here

  • @noornzar9305
    @noornzar9305 Рік тому

    Medical students need more videos like this

  • @ecedenizturan784
    @ecedenizturan784 9 місяців тому

    Excellent excellent excellent explanation thank you

  • @anime2002LOL
    @anime2002LOL Рік тому

    رائع جدا
    شكراً لجهودك العظيمه 🥰🌟

  • @xZenize
    @xZenize 6 років тому +3

    Your videos are soooo helpfull, but im really having trouble with understanding the mechanisms of cytokines. I would be so thankfull if you could explain a little bit about cytokines! Thanks in advance you're the best!

  • @vartikashukla8914
    @vartikashukla8914 3 роки тому

    Wowwww...fabulously explained
    Thankyou so much🙏❤

  • @mitalipriyadarshani2526
    @mitalipriyadarshani2526 3 роки тому

    You are awesome and unique😍😍 you cleared my baseline concept👍Thank you so much

  • @saravera5784
    @saravera5784 5 років тому +1

    Wonderful video. It's Malaria & BABESIOSIS in extracorpuscular haemolysis. Bartonellosis includes Cat Scratch disease, Trench Fever & Bacillary Angiomatosis.

    • @snigdhashanti6839
      @snigdhashanti6839 5 років тому +1

      perfect!! wondering how no one corrected it. Also isnt it G6PD Deficiency?

  • @mohammedabd6696
    @mohammedabd6696 4 роки тому +1

    You are fabulous

  • @sivilifestyles
    @sivilifestyles 2 роки тому

    fantastic explaination 😊

  • @joy4336
    @joy4336 6 років тому +4

    Nice video...need more

    • @DentalClinician
      @DentalClinician 5 років тому +1

      ua-cam.com/play/PLT0nQuD9NwdlltAaSinDkdsTRUfBSob4l.html

  • @raycagegaming
    @raycagegaming 5 років тому

    I came here for the G6PD deficiency explanation and it did not disappoint.

  • @shahzaibkhan-jo9fn
    @shahzaibkhan-jo9fn 6 років тому +2

    Amaaaaaazing dear

  • @patriciadesouzapimenta5127
    @patriciadesouzapimenta5127 2 роки тому

    Great video!! thank you!

  • @sz93-p5i
    @sz93-p5i 6 років тому +1

    That pdf make me thankful ♥️

  • @santiagoespiritualidad3857
    @santiagoespiritualidad3857 6 років тому

    Hola amigos son geniales,un abrazó desde colombia

  • @daniadm1223
    @daniadm1223 2 роки тому

    Very helpful thanks 😊

  • @rohitpadme1478
    @rohitpadme1478 6 років тому +3

    3 am .in india...osm..👍

  • @praveenavr2747
    @praveenavr2747 5 років тому

    Its very usefull to dental students also

  • @santiagomaciasvillegas2186
    @santiagomaciasvillegas2186 6 років тому +1

    Son geniales amigos,un abrazo desde San Jerónimo Antioquia colombia

  • @abdullahmohammed2553
    @abdullahmohammed2553 6 років тому +1

    very helpful. Thank you very much

  • @luichilml
    @luichilml 5 років тому

    YOUR VIDEOS ARE GREAT!

  • @TheFirozRizvi
    @TheFirozRizvi 4 роки тому

    So helpful! Thank you!

  • @moathbanimelhem1860
    @moathbanimelhem1860 5 років тому

    Keep going you are doing amazing work

  • @kay6914
    @kay6914 5 років тому

    Amazing!! You made it so simple ❤️

  • @naveenan8709
    @naveenan8709 Рік тому

    Hello sir ,can u tell how hemolytic anemia can affect the function of other essential organs ?

  • @lesliecooper801
    @lesliecooper801 5 місяців тому

    Erythroid progenitor not myeloid but great video overall. Thank you

  • @rushikeshharne3194
    @rushikeshharne3194 6 років тому +2

    Loved it

  • @joannadaniel9396
    @joannadaniel9396 17 днів тому

    thank you!

  • @muhammadkamran4798
    @muhammadkamran4798 5 років тому

    Mind blowing

  • @kasunsanjeeva8787
    @kasunsanjeeva8787 5 років тому

    supper explanation

  • @TheSaneInternational-SNI
    @TheSaneInternational-SNI 6 років тому +1

    its 3 am!!
    love from India 😊😊

  • @anuragtiwari917
    @anuragtiwari917 4 роки тому

    In warm autoimmune hemolytic disease, body temperature is at 37 degrees only.

  • @hammhann3818
    @hammhann3818 4 роки тому

    Thaaaaaaanx 🌹❤️🌹🎉

  • @meloked7516
    @meloked7516 3 роки тому +1

    is G6PD should intravasculer haemolysis, right? its make hemoglobynuria so it should be intravasculer hemoliysis

  • @dinaalbushra5364
    @dinaalbushra5364 2 роки тому

    Amazing thank u

  • @prikwilson
    @prikwilson 6 років тому +1

    Kindly add a video on emergency drugs if possible..

  • @aytakchichak7456
    @aytakchichak7456 4 роки тому +1

    thanks alot.How can we get the pdf of your drawings plz?

  • @shimadavari4501
    @shimadavari4501 5 років тому

    best out of best

  • @berserkberry9284
    @berserkberry9284 5 років тому +1

    Armando, you've got an attractive voice.

    • @nazzib3657
      @nazzib3657 5 років тому

      Ashwarya jain
      Girl calm down

  • @maro9999999991
    @maro9999999991 4 роки тому

    Genius !!

  • @SpacelessTimeless
    @SpacelessTimeless 4 роки тому

    It is actually G6P”D” deficiency, “D” is stand for Dehydrogenase

    • @prosurgeon6957
      @prosurgeon6957 3 роки тому

      im sure he knows that 2 years later : )

  • @bilalturkan8004
    @bilalturkan8004 Рік тому

    G6PD deficiency causes intravascular hemolysis hence patients present with haemoglobinuria which is dark or red urine often mistaken as haematuria.

  • @medicosthings...8132
    @medicosthings...8132 6 років тому +11

    Please use English subtitles in your videos because of difference pronunciation if different country

  • @farzanasharminnipa7812
    @farzanasharminnipa7812 Рік тому

    Thank you

  • @JR-gv4ew
    @JR-gv4ew 3 роки тому

    Thank u Sir

  • @Reem-ki4fj
    @Reem-ki4fj 2 роки тому

    perfectly perfect

  • @nal9345
    @nal9345 5 років тому +6

    it would be nice if you upload what you draw as a pdf, so i can print and study it. please consider this:(

    • @emrebaris8085
      @emrebaris8085 5 років тому

      It's on his website.

    • @DentalClinician
      @DentalClinician 5 років тому +1

      ua-cam.com/play/PLT0nQuD9NwdlltAaSinDkdsTRUfBSob4l.html

  • @TheX7mood
    @TheX7mood 4 роки тому

    Well explained!!

  • @ClaraLL
    @ClaraLL 6 років тому

    Good Stuff :)

  • @imperiusss
    @imperiusss 5 років тому +5

    But with G6PD deficiency, you have also intravascular hemolysis, not only extravascular!

  • @13haiamrit
    @13haiamrit 3 роки тому

    Haptoglobin is less because in Hemolytic Anemia, it is being used up a lot than usual??

  • @jk1239
    @jk1239 2 роки тому

    Sir please tell how to get your notes pdf plz 🙏

  • @hazalsarird1219
    @hazalsarird1219 4 роки тому

    video ends unexpectedly :D

  • @EssexEx
    @EssexEx 2 роки тому

    Wouldn’t haptoglobin levels increase if there’s more haeme in circulation? Or are they not produced more in proportion to the haeme increasing in the body?

    • @Mariam-g9e
      @Mariam-g9e Рік тому

      Hemoglobin actually binds with heptoglobin and this complex is eaten up by macrophages that's why heptoglobin level decreases

  • @srirambhardwaj2343
    @srirambhardwaj2343 5 років тому

    Thank.you.very.much.sir.

  • @AlohaUlises
    @AlohaUlises 6 років тому +3

    Kundos on you getting a sponsor!!! Great!!!! :D :D

  • @GeorgeAscue
    @GeorgeAscue 6 років тому

    Thanks

  • @GhulamMurtazaDahar
    @GhulamMurtazaDahar 6 років тому

    which software do you use?

  • @mroosie7488
    @mroosie7488 5 років тому +12

    I'm here 1 day before my finals..

  • @ozzyoz6206
    @ozzyoz6206 6 років тому +2

    Your legacy will be bigger than Netter

  • @muhammadidrees5172
    @muhammadidrees5172 3 місяці тому

    Notes available please

  • @knightstormbringer
    @knightstormbringer 6 років тому +1

    Just to clarify, G6PD is intravascular, right?

    • @armandohasudungan
      @armandohasudungan  6 років тому +2

      Hey, its one of those which are both intravascular and extravascular most likely. But because it is abnormal will definitely be cleared up by the spleen/liver.

  • @suryaa109
    @suryaa109 2 роки тому

    What's the permanent solution for hemolytic anemia?

  • @goncalosanhudodeportocarre9591
    @goncalosanhudodeportocarre9591 6 років тому +1

    Great video, like always, but isn't the sound cut off at the end?

    • @armandohasudungan
      @armandohasudungan  6 років тому +1

      Haha you are right. It was meant to say extracorpuscular and intracorpuscular causes of haemolysis. Cheers!

  • @Jen6374
    @Jen6374 5 років тому +2

    I have this No fun I was 2 pints short of blood almost killed me I had transfussion

    • @patriciawilder66
      @patriciawilder66 5 років тому

      How do you find out if you are short of blood, I've been sick with this anemia for some time, getting much worse, constantly needing to sleep, and dizzy all the time 😪

  • @harinipreethi5932
    @harinipreethi5932 3 роки тому

    Why neutrophilia and thrombocytosis in hemolytic anemia

  • @sayyedsayam8158
    @sayyedsayam8158 4 роки тому

    2 nd half month to go for Exams

  • @lunamoondrop
    @lunamoondrop Рік тому

  • @rehabhh5834
    @rehabhh5834 Рік тому

    But g6pd deficiency is intravasculer hemolysis

  • @shaimaa1611
    @shaimaa1611 Рік тому

    Wow

  • @stelonkangabam4567
    @stelonkangabam4567 5 років тому +2

    I wanna marry this guy😂

  • @ريحانةريحانة-ر7ط6ق
    @ريحانةريحانة-ر7ط6ق Місяць тому

    هل يمكن اضافة لغة عرببة

  • @samsungm4124
    @samsungm4124 Рік тому

    WTH?!
    G6pd is intravascular not extravascualr hemolysis

  • @user-xn8dp5zy8t
    @user-xn8dp5zy8t 6 років тому +1

    Allow the ads bro

  • @anasalhumaidi6775
    @anasalhumaidi6775 Рік тому

    ياريت يترجم كلامه للعربي

  • @fikrikiky8445
    @fikrikiky8445 6 років тому

    Like

  • @Arbazkhan-qe1mu
    @Arbazkhan-qe1mu 6 років тому

    Not bad

  • @Prachee1318
    @Prachee1318 6 років тому

    ew your accent

  • @Arbazkhan-qe1mu
    @Arbazkhan-qe1mu 6 років тому +1

    Somewhat boring

    • @CynBH
      @CynBH 6 років тому +14

      Yours is a somewhat unnecessary comment. It's a medical lecture, not an action movie. It's meant to be informative (which this video is), not entertaining. Those of us who are trying to learn are actually interested.

    • @kamaltahir6440
      @kamaltahir6440 6 років тому +1

      It's interesting actually

    • @stelonkangabam4567
      @stelonkangabam4567 5 років тому

      It's interesting actually and helpful as well.

    • @reefraz6963
      @reefraz6963 5 років тому +1

      Ur in wrong channel. Plz go away n delete ur comment as well

    • @DentalClinician
      @DentalClinician 5 років тому +1

      @@reefraz6963 ua-cam.com/play/PLT0nQuD9NwdlltAaSinDkdsTRUfBSob4l.html

  • @user-fi5mn8gv4z
    @user-fi5mn8gv4z 3 роки тому

    thanks