Interesting. Mechanism seems to make sense given the antioxidant activity of glutathione. Did they control glutathione levels in the diet of all participants or does supplementation provide a supramaximal dose which makes dietary glutathione negligible?
Thanks doctor, as always another great and informative video. I’m a big follower now after a previous video really helped my condition. Where can you purchase topical glutathione?
Thanks for your kind comments. I am not sure how many products are available in India. I have googled it and here is one I found on amazon India. However, Im sure there are quite a few other products and dermatologists in India may help you with it. www.amazon.in/Trycone-Glutathione-Whitening-Ageing-Vitamin/dp/B07RZXVBX4
It may lighten the skin in some of those who take it. However, not sure if it will brighten the skin. Making it lighter may result in a brightening effect I guess. The oral supplement seems safe in the long term but data of more than a few years is lacking at present.
Philippines!!!!! Yes it's very popular here in the Philippines esp with our celebrities and models. IV glutathione is very effective for whitening and immune booster however oral glutathione is good as an antioxidant supplement.
Hi Doctor, really great review. Can I ask if it safe to use up to 50,000 MG daily of Gluthatione, aim not for lightening but as an antioxidant and anti aging agent. I was told a product called glucenta diamond is good, but the dose is 50,000mg.
I have not heard of such high doses being used for skin conditions. It may be better to use natural modalities like diet to have young appearing fair skin. Here is a video on it. ua-cam.com/video/cqvmt6bYWFI/v-deo.html There are other natural ways of maintaining young skin. Here is a video called Healthy skin, which explains it ua-cam.com/video/CB2D3NUTzDI/v-deo.html Finally, using tinted sun screens on the facial skin will prevent darkening. Here is a video on it ua-cam.com/video/u3cPL4T1g3c/v-deo.html
There are a few creams that can help lighten facial skin,. Here isa video on it ua-cam.com/video/nCAI4PE073k/v-deo.html Using tinted sun screen will also ensure that the existing skin tone does not darken further. Here is a video on it ua-cam.com/video/u3cPL4T1g3c/v-deo.html
It may work for some, but not everyone has benefits from the medication. There are a few creams that can help lighten darker skin on the face. here is an evidence based article that I reviewed earlier ua-cam.com/video/nCAI4PE073k/v-deo.html We also need to ensure that we prevent any sun induced pigmentation by using tinted sunscreens ua-cam.com/video/u3cPL4T1g3c/v-deo.html
There is no direct effect of smoking on glutathione as far as I am aware. For general skin health though, smoking is not ideal. Here is a video that explains this. This looks at all the life style factors that help us have good looking skin. ua-cam.com/video/CB2D3NUTzDI/v-deo.html
In the UK, its the opposite, most want to have tanned skin, so I have not had to use this supplement before. It is very commonly used in the subcontinent and in the Philippines, where not was first tested. In fact, I gather it is given as an IV rather than orally, which makes it more likely to have potential side effects. Most dermatology treatments are not licensed as the there are so many conditions where rigorous studies have not been conducted. Dermatology is mostly an "empirical" subject where doctors use medications that they have been taught to use even though many do not have the double blind scientific evidence that other specialities have. It suggests that more research is needed in dermatological conditions. I try to post research that is double blind and has proof that it worked in scientific studies.
Yes, there are good reports of topical glutathione being helpful too. There are other topical agents that can lighten darkened skin and this is covered in this video. The creams towards the end of the video are available over the counter. ua-cam.com/video/nCAI4PE073k/v-deo.html
Doc, i have occasional pimples but when i do have it takes a while to go and the acne scar remains, the marks are darker and doesnt fade away whats the best way to get rid of it?
There are a few creams that can help reduce facial pigmentation. This vide covers a few of the evidenced based treatments for it. ua-cam.com/video/nCAI4PE073k/v-deo.html
Hii Doctor Had a lot of acne in my teenage but after consulting dermat got rid of those however those acne have remained acne scars which are called as pit scars. Can you help
You are right that scars are more resistant to treatment compared to the active lesions. A variety of treatments including topical retinoids, lasers, peels and dermabrasion have bene used. It may be best to see a dermatologist or Plastic Surgeon.
Thank you for making this video. I'm in USA and this April 13th I took a Determetolagist appointment, I was gonna ask about glutathione 😅. We are planning for pregency this November. So is it safe to take glutathione now?
Generally, most clinicians would like no oral medications to be taken when pregnancy is being considered. Even though glutathione is natural, there have been non studies about its effects on pregnancy. It may be worthwhile using topical (cream) glutathione as that may be safer in pregnancy.
Dr mere nak pe scars he 1 wo sai nai hora 2sal se mene acne scars cream use ki he osse bhi sai nai hoa to Kia use Kare jisse sai hojayy opan pors bhi sai hojay
Hi, I do not know Hindi but I think you are asking about the treatment of acne scars. I have not done any specific videos on acne scars but if they are dark in colour, the treatments mentioned in this video may help ua-cam.com/video/nCAI4PE073k/v-deo.html Also, make sure that the acne is completely under control. Here are a few tips on how to treat acne in Indian skin. ua-cam.com/video/_4PPrl98mi4/v-deo.html
Hi doctor, I am taking oral glutathione at a dosage of 500mg per day . Will it show me results . It’s been around 3 months I have already used but none improvement so far
Supplements may not work in all those who take it. IIt could be beneficial for a majority but there will be some in whom there is no effect. It is important to combine oral agents like glutathione with topical agents like tinted sunscreens to ensure that the existing pigmentation does not worsen. Here is a video on it ua-cam.com/video/u3cPL4T1g3c/v-deo.html
Most supplements are not tested in those who are pregnant. So it may be worthwhile avoiding during pregnancy. If used, a very low dose would be considered.
@@DiscoverDermatology What about liposomal glutathione? for exemple is 500mg of liposomal glutathione more effective than 2000mg of basic oral glutathione? due to bioavailability
Its not really effective for skin lightening I have taken ivs not a single tone improvement I get from it I were bron with fair skin (yellowish) but unfortunately it changed long yr back mybe bad genetics or sun exposure..this all gluta brands just doing their business name of lightening
You are right that not everyone will benefit from glutathione treatment. In every study, there is bound to be failure for at least a few of those who use it. Science just shows if it could be helpful for at least a group of those who use the treatment.
Short and sweet videos doctor, please keep it up
Welcome Kevin, glad you liked it!
Me too
Interesting. Mechanism seems to make sense given the antioxidant activity of glutathione. Did they control glutathione levels in the diet of all participants or does supplementation provide a supramaximal dose which makes dietary glutathione negligible?
Good point. They did not mention it in the study protocol. I suspect it will be difficult to control diets in a study like this.
Thanks doctor, as always another great and informative video. I’m a big follower now after a previous video really helped my condition. Where can you purchase topical glutathione?
Thanks for your kind comments. I am not sure how many products are available in India. I have googled it and here is one I found on amazon India. However, Im sure there are quite a few other products and dermatologists in India may help you with it.
www.amazon.in/Trycone-Glutathione-Whitening-Ageing-Vitamin/dp/B07RZXVBX4
Would you recommend it to be taken for skin brightening and is it safe to take glutathione supplements
Long term or is a break needed ? Thanks
It may lighten the skin in some of those who take it. However, not sure if it will brighten the skin. Making it lighter may result in a brightening effect I guess. The oral supplement seems safe in the long term but data of more than a few years is lacking at present.
Philippines!!!!! Yes it's very popular here in the Philippines esp with our celebrities and models. IV glutathione is very effective for whitening and immune booster however oral glutathione is good as an antioxidant supplement.
Its interesting to note the history of the use of glutathione in the Philippines. Thanks for sharing.
Hi Doctor, really great review. Can I ask if it safe to use up to 50,000 MG daily of Gluthatione, aim not for lightening but as an antioxidant and anti aging agent. I was told a product called glucenta diamond is good, but the dose is 50,000mg.
I have not heard of such high doses being used for skin conditions. It may be better to use natural modalities like diet to have young appearing fair skin. Here is a video on it.
ua-cam.com/video/cqvmt6bYWFI/v-deo.html
There are other natural ways of maintaining young skin. Here is a video called Healthy skin, which explains it
ua-cam.com/video/CB2D3NUTzDI/v-deo.html
Finally, using tinted sun screens on the facial skin will prevent darkening. Here is a video on it
ua-cam.com/video/u3cPL4T1g3c/v-deo.html
@@DiscoverDermatology thank you
Very good Scientific lecture given in a nice way Thanking you so much Sir 🎉
Thanks Rajagopal!
Can you recommend products that are good and safe to use?
There are a few creams that can help lighten facial skin,. Here isa video on it
ua-cam.com/video/nCAI4PE073k/v-deo.html
Using tinted sun screen will also ensure that the existing skin tone does not darken further. Here is a video on it
ua-cam.com/video/u3cPL4T1g3c/v-deo.html
@@DiscoverDermatology how about pills. I have those other products.
I use Luma Glutathione I take 2 capsules 500mgs a day with a meal the way the directions instructed..will that lighten my skin?
It may work for some, but not everyone has benefits from the medication. There are a few creams that can help lighten darker skin on the face. here is an evidence based article that I reviewed earlier
ua-cam.com/video/nCAI4PE073k/v-deo.html
We also need to ensure that we prevent any sun induced pigmentation by using tinted sunscreens
ua-cam.com/video/u3cPL4T1g3c/v-deo.html
Hii Thanks for the video, Does smoking affect glutathione??
There is no direct effect of smoking on glutathione as far as I am aware. For general skin health though, smoking is not ideal. Here is a video that explains this. This looks at all the life style factors that help us have good looking skin.
ua-cam.com/video/CB2D3NUTzDI/v-deo.html
Jus like oral minoxidil which is not FDA approved, is glutathione too used by dermatologist in practice ??? Pls give your answer dr
In the UK, its the opposite, most want to have tanned skin, so I have not had to use this supplement before. It is very commonly used in the subcontinent and in the Philippines, where not was first tested. In fact, I gather it is given as an IV rather than orally, which makes it more likely to have potential side effects.
Most dermatology treatments are not licensed as the there are so many conditions where rigorous studies have not been conducted. Dermatology is mostly an "empirical" subject where doctors use medications that they have been taught to use even though many do not have the double blind scientific evidence that other specialities have. It suggests that more research is needed in dermatological conditions. I try to post research that is double blind and has proof that it worked in scientific studies.
Doctor, is it safe to use topical glutathione?
Yes, there are good reports of topical glutathione being helpful too. There are other topical agents that can lighten darkened skin and this is covered in this video. The creams towards the end of the video are available over the counter.
ua-cam.com/video/nCAI4PE073k/v-deo.html
Doc, i have occasional pimples but when i do have it takes a while to go and the acne scar remains, the marks are darker and doesnt fade away whats the best way to get rid of it?
There are a few creams that can help reduce facial pigmentation. This vide covers a few of the evidenced based treatments for it.
ua-cam.com/video/nCAI4PE073k/v-deo.html
Thank You . Concise and informative .
You are welcome, glad it was helpful!
Hii Doctor
Had a lot of acne in my teenage but after consulting dermat got rid of those however those acne have remained acne scars which are called as pit scars. Can you help
You are right that scars are more resistant to treatment compared to the active lesions. A variety of treatments including topical retinoids, lasers, peels and dermabrasion have bene used. It may be best to see a dermatologist or Plastic Surgeon.
Dr can we take glutathione with traxemic tablet for melasma pls guide .
Yes, they can be used together.
@DiscoverDermatology thank you Dr. Prayers for you 🙏
Thank you for making this video. I'm in USA and this April 13th I took a Determetolagist appointment, I was gonna ask about glutathione 😅. We are planning for pregency this November. So is it safe to take glutathione now?
Generally, most clinicians would like no oral medications to be taken when pregnancy is being considered. Even though glutathione is natural, there have been non studies about its effects on pregnancy. It may be worthwhile using topical (cream) glutathione as that may be safer in pregnancy.
Is there any problem in taking pearlite max tablet 600mg for 3 months?
Not sure what pearlite max contains?
@@DiscoverDermatology I am in Wrexham . Can we get glutathione oral tablets here?
@@pinkcorner9989 Yes, it is available in most health food shops like Holland and Barrats. It is also accessible online.
Interesting topic, thank you!
You are welcome!
Dr mere nak pe scars he 1 wo sai nai hora 2sal se mene acne scars cream use ki he osse bhi sai nai hoa to Kia use Kare jisse sai hojayy opan pors bhi sai hojay
Hi, I do not know Hindi but I think you are asking about the treatment of acne scars. I have not done any specific videos on acne scars but if they are dark in colour, the treatments mentioned in this video may help
ua-cam.com/video/nCAI4PE073k/v-deo.html
Also, make sure that the acne is completely under control. Here are a few tips on how to treat acne in Indian skin.
ua-cam.com/video/_4PPrl98mi4/v-deo.html
Interesting video Diva
Thanks mama!
Hi doctor, I am taking oral glutathione at a dosage of 500mg per day . Will it show me results . It’s been around 3 months I have already used but none improvement so far
Supplements may not work in all those who take it. IIt could be beneficial for a majority but there will be some in whom there is no effect. It is important to combine oral agents like glutathione with topical agents like tinted sunscreens to ensure that the existing pigmentation does not worsen. Here is a video on it
ua-cam.com/video/u3cPL4T1g3c/v-deo.html
Can i taken it during breast feeding??
Most supplements are not tested in those who are pregnant. So it may be worthwhile avoiding during pregnancy. If used, a very low dose would be considered.
intravenous Glutathione is way stronger than oral, due to oral's poor bio-availability despite lozenges first liver pass
Thats is correct. However, the long term side effects of IV glutathione are still unknown and may become apparent many years later.
@@DiscoverDermatology What about liposomal glutathione? for exemple is 500mg of liposomal glutathione more effective than 2000mg of basic oral glutathione? due to bioavailability
@@manisx7490 Not sure. I have not used or researched into liposomal glutathione myself.
Make sure it’s liposomal glutathione
Interesting point
Its not really effective for skin lightening I have taken ivs not a single tone improvement I get from it I were bron with fair skin (yellowish) but unfortunately it changed long yr back mybe bad genetics or sun exposure..this all gluta brands just doing their business name of lightening
You are right that not everyone will benefit from glutathione treatment. In every study, there is bound to be failure for at least a few of those who use it. Science just shows if it could be helpful for at least a group of those who use the treatment.