A Vaccine That Makes Your Immune System ... Forget?
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- Опубліковано 21 гру 2023
- Vaccines for covid or the flu teach your immune system to remember a threat so that it responds when that threat shows up. Some researchers want to delete immune memories instead, because those aberrant memories are the cause of autoimmune diseases like MS, Celiac, and Crohn's disease.
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As a transplant recipient who relies on massive doses of immune suppressing medications to keep my donors organ safe I can't help but hope some day this can be used to help people like me.
I have a friend who had a transplant and explained this, this is the first thing that popped up to my head. I really hope this works out!
I may soon be joining you, if events proceed as expected.
Same here friend, cheers for that.
I’m a kidney transplant patient! This is huge!!!
Wouldn't your body just retarget the transplant? YKnow, since it isn't your bodies cells
As someone who suffered crippling allergies earlier in life who was allergic to literally every single thing I was tested on and who still has an autoimmune disorder, this is great news.
im right there with you too, definitely not suffering alone lmao. imagine someone actually doing something about autoimmune disorders like this! It seems sometimes like nobody cares, truly, in research nd health... IT's all just treating symptoms and shrugging the rest of the time....
This is dangerous we shouldn’t be playing god with stuff that should be left alone
@@BargerClan I think we unfortunately crossed that bridge a long time ago when we started doing things like weaponizing viruses and bacteria. Every technology has the potential to do harm as well as good, and short of suspending all technological progress usually the best we can do is try to use new technology wisely and suspend the most dangerous iterations, which is why we've done things like ban certain types of extremely dangerous weapons entirely and limit the proliferation of others.
Honestly if you want to hear about something far more dangerous and shocking in its implications...look up Operation Sea Spray. The US Navy in 1950 decided to do bioweapon defense testing in San Francisco with a supposedly harmless microbe. The public had no idea, gave no consent, and it wasn't as harmless as they thought it was. That they would do something like that without any consent or even simply telling people in the supposed bastion of the free world in the 20th century is absolutely mind boggling. 😮😮 I think the only thing we can really say is such was the incredible fear of the USSR during the Cold War.
@@BargerClanI agree. We have a come a long way but I think we are getting a little to comfortable with experimenting with stuff.
@@BargerClan you say that now but if you're sick with autoimmune disease you'll get the treatment anyways. The religious always complain at first, but in the end they'll be customers of the latest breakthroughs just like everyone else.
As someone with a chronic autoimmune that is not curable and caused by an inflammation something like that would be life changing for me.
just get more covid boosters
Vaccines are the cause of your autoimmune disease, not the solution.
This is so cool! Imagine a day when doctors routinely say things like, "It seems you have diabetes. I'll schedule you for an outpatient liver biopsy next week so we can prepare your Invax-D, you should be fine on that for a couple weeks, then you'll be good to go. Just watch your sugar intake until then, okay?"
lol and give up all those insulin profits? Bless your heart.
@@p0llenp0nyThis isn't the dialysis industry.
@@gljames24 They're trying.
@@p0llenp0ny *Sigh* You sound like my conspiracy theorist father, who was convinced "there is a cure for cancer, but 'they' are covering it up because doctors make more money from repeat cancer treatments than from cures."
I spent most of my life trying to talk some sense into him, especially when I eventually got to university to study biomedical engineering with a focus on cancer research, but I eventually learned that people who see the worst in "them" (whoever "they" are) cannot be reasoned with. And it's just tiring trying to.
So you have a nice life, friend. A life free of polio, despite somehow Big Iron Lung, and one free of smallpox despite Big Tecovirimat. Enjoy the life you've chosen to use to assume everyone wants you sick, which you've been given in part by people who have made sure you're less likely to get sick.
The only thing with type 1 diabetes is that u dont have any beta cells anymore so youd need new ones. There was an attempt at a cure a few years back that took fetal stem cells (which are different from non-fetal stem cells because they can become anything) and made them into beta cells but when they were put into test subjects, the immune system just killed them again. If both of these were combined, that could potentially be an actual cure
Cant wait for them to do this for crohns and colitis. Bit rude to go after my bowels just for existing
It would be life changing. Only had colitis for a year and im so tired of it. Also randomly getting allergies and inflammation in my gum, its like my body doesnt want to exist anymore. From being perfectly fine.
@@XirpzyIn the same boat with crohns
childhood vaccines caused your crohns, it's not the solution to them.
Helping people who suffer from autoimmune diseases like me is the reason i want to go into biomedical engineering/general biomedical lab work. Its been so hard for me to even figure out what's happening and how to adjust to life with my chronic illnesses, and I want everyone to have proper access to adequate, affordable, and accurate testing. I hope this takes us a step forward, and I hope future generations have it easier in the unknown world of autoimmune disease.
Vaccines are the reason you suffer from autoimmune disease.
My celiac can be defeated....I can't tell you how excited I am... and weeping? I don't know how to feel about this news. But I'm excited to see where this goes
Can you even imagine not having to worry about going to lunch with people, or if the beans you bought were processed on the same machines as wheat? Or having a sandwich made with bread that wasn't like eating sugar flavored paper, and didn't cost three times as much? Or having a dog and their dog food didn't make you sick? I hope it doesn't take them 10 years to do this. Fingers crossed!!!!
I'll race you to the front of the line! 😂
@@musingwithreba9667 heck ya! I'm so excited!
@@shakeyj4523 and not having to read labels anymore. Or being able to have a normal date with my wife. Or not having to ask the waiter a hundred questions only to find out they are not safe to eat at
if they don't understand the disease well enough to prevent it/treat it, they can't say this works.
I love when my immune system is so good they attack my myelin sheath 🧠
I know right. I love when mine attacks my spinal cartilage.
Mines attacks my neighbors
@@williamkirkland2222 Human body is a perfect machine nothing is wrong with it... :(
Your immune system is a finely trained army.
Autoimmune diseases is a bit like your finely trained army is filled by The Keystone Cops led by Frank Drebbin (the guy from The Naked Gun movies).
Mine is even better... it also attacks my intestine and my spine. The triple threat.
I have several auto immunes. I'm 70, and they've really taken their toll, so it probably won't help me. But for my nieces, friends kids and grands, This would be a wonderful thing 🤞🏽🙏🏽❣️💜💙💜
I hope they do this for Crohns Disease soon as well
your childhood vaccines caused your crohns, another injection won't cure you. If they can't cure you without an injection because they don't understand the disease well enough to do so, this won't help.
YES! This can't come fast enough. I have a terrible case of primary progressive MS which can't even be suppressed (the only medication is Ocrelizumab with the best case outcome of "hey, it'll only get worse with 70% of the speed") and this year has been especially devastating. Having the outlook of walking again in a couple of years is the best christmas present you could give to me.
I hope it happens for you. I'm on the same drug, but I'm new enough to the MS Family we think I only have RRMS so far.
You will walk again. 🫰🏻
As a T1D who also has a son and daughter-in-law who are also T1D, this video brought me to tears. Imagine being able to determine the existence of genetic markers for a disease, and tailor a few injections that will prevent a lifetime of suffering! That would be so amazing!
MS treatment is looking promising. Lucid MS from FSD Pharma just finished Phase 1 human trials and now I learn about these "anti-vaccines" being studied in Germany! Thanks for publishing your souces SciShow team! In 3-5 years maybe I'll be able to walk again!
yes but any of the thsoe phase 1 human trials got got covid-19 in 2020-2022 in the usa trials died bescue the covid-19 virus bascly was made by china to take advatage of it when in the same body that had the ms treatments to bascly have super leathel levels on perpose. i have seen those reults myself. never ever get ms treamtns when you got a covid-19 virus bescue chnia made that virus to take full advantage to highjack the bodys antigen maker sistem in the liver that then alow covid to bascly have no resace for your own imnuse sistem unbale to fight back. how else why covid-19 was such a big mencae when it got out of the labs bescue chnia made it that way on persoe with the genticaly engrenad anti obdy makerers that wrement to be used with ms treamants to bascly used as a mulvector anit imnusistem antibody conter mensues.
Fingers crossed! You will walk. ☝🏻
I couldn't find anything that says it's being studied in Germany, where did you get that from?
I’m rooting for you, one MS fam to another!!
YES! Fingers crossed 🤞 🙏 I would love to have full use of my dominant hand and full cognition restored. ❤ From one MS Warrior to another.
If they don't call this a baccine (back-seen), they're missing a major opportunity.
Unccine. It makes your immune system unsee.
Can't wait until all the anti-vaccers try and do that to "reverse their child's autism."
a rollvacc
Eniccav. Plural will be seniccav, naturally
@@QwoaXcan they give this to anti vaxxers to cure their pretend see?
As someone with MS, this could be a game changer in a lot of ways.
I really hope it works perfectly and there comes a day when we only speak about MS in past tense, or as one of those things that people sometimes experience briefly in childhood and then never again.
Another MSer here.
My mom has MS, for good 18 years or so. She is near 60yo and not mobile. As someone who had a chance to see the development of this disease I wish we - as humanity - had any way to eradicate it once for all.
@@laviwastaken9845 It looks like we might. I hope it works, and that it's able to help your mother.
Yes, PPMS is what Nuerologist says and it has a very depressing year not being able to work 😢.
I wonder if this could also help with organ recipients
That's a really good point!!
I was thinking about that too. It'd be huge
Sure seems like it ought to!
Heart transplant recipient here. This sounds like a good start. The anti-rejection drugs are the hardest part.
I have MS and this has me is tears, feels like we are so close.
That would be a massive advancement in treating or even curing autoimmune diseases!
Or itd give you a new disease.
Good! Because 10% of you who got flooded with a certain spike protein, now have autoimmune diseases. You best hope that these baccines do make progress.
@@nico3727or curing immune diseases
@@nico3727 How
@@Jongivitis maybe by having the immune system "forget" that specific protein, an bacteria or virus with the same protein can go under the radar. But i could be completely wrong, just a guess
Honestly i think even if this just becomes a way to prevent type 1 diabetes and other diseases i think its absolutely worth it. Ive been suicidal because of my diabetes and preventing others from having to go through that and risk them losing the fight, its worth it. I also knew someone who lost their battle with depression after nothing helped their MS symptoms. The amount of pain everyone around them felt was extreme. If we can treat or prevent these conditions, lives can be saved
After a few more decades of development and experiments, this would be amazing for lupus, rheumatoid arthritis, and Crohn's patients, among other sufferers like those with Hashimoto's thyroiditis.
As someone with alopecia, osteoarthritis and eczema... I hope this vaccine works soon!! 🤞🤞🤞
Only $600,000 a dose!
@@p0llenp0nyI've seen you commented defeated statements like this. You are right that capitalism is broken but really, allow people to be hopeful. 😨
@@VizzyInks Defeated? lol It's the reality. You can pretend it isn't, I suppose.
Thats in the US. In Europe is will probably be waaaay cheaper
Osteoarthritis? IDK. Rheumatoid arthritis it should work for.
This comment section - and all of us in it who are so desperately hoping for this technique to lead to real-world treatments/cures - shows how devastating these diseases can be and how rotten the current treatment options are. Phase 1 is very early in the process, but having hope is everything.
10% of the population now have an AD since 2019. Having a brain is more important.
Autoimmune disease feels like your own body is at war with you. I imagine cancer patients feel the same. You cannot just fight it with a positive attitude because you are fighting your own body. You also keep wondering when you are in remission, whether it will come back. You can be constantly on the lookout for returning symptoms. Then there is the concern about being in contact with people that might be infectious with something because you are immunosuppressed.
Would LOVE to see an episode of the anime "Cells at Work!" about this. A special ops robot virus breaks into the body and goes through Bond-esque levels of shennanigans all to cross "pancreas" off the Immune Systems Enemies List. Amazing.
omg. Make that webcomic and I'll support your patreon
As somebody with MS I have followed the progress of this for ages. I am SUPER excited about it. If it works and passes human trials I could finally not have to actively damage my immune system
I've just had a confirmed diagnosis of Coeliac Disease. For now I'm getting started on the gluten-free diet, but it's great to think I might not always have to!
1:14 - It's ironic, because my Father has diabetes, my sister has celiac disease and my mom has multiple sclerosis. I am not kidding.
I have Celiac Disease, my Mom has Psoriasis, and my Dad and Grandmother had Diabetes. I'm not kidding either.
my sis has Diabetes, mom died of MS, I have MS. no joke
Do you have Psoriasis as well, perhaps?
I have hashimoto's, mother has MS + pernicious anaemia, her dad has T1 diabetes + psoriasis + parkinsons (and several of his siblings also have T1D or other ai disorders, and their mother had something going on but too long ago to have been diagnosed I guess). other immediate relatives with disorders and in the diagnostic process too. Specialists call us the perfect cluster!
I know I have markers for rheumatoid arthritis, and also something wacky happening after a super bad run in with covid a year ago now. Waiting til jan to see my dr...
@@tphotos3485 I just read an article (scientific) about having suspicions that Covid can trigger Rheumatoid Arthritis and other autoimmune disorders. Interesting. I hope your tests are negative.
I knew immediately what this was about as someone with so many allergies T_T
same, I miss cheese and bread
This would be so amazing!! I am a type 1 diabetic, and one of my biggest fears is passing it to my kids! If this vaccine were to be approved, I’d be so happy with the prevention side of it 🥰🥰🥰
I love when my immune system is so good it attacks harmless peanuts
Then it's not good.
I needed this in my life. As someone who has always struggled with an autoimmune disease that I was born with. Superset drugs have helped greatly but then leaves me exposed to everything else. Thank you to everyone who has donated and researched for years on this kind of stuff. It is hard work but it is greatful work.
Same here I’m hopeful for something like this in the near future even if it is ten years away
I have Ulcerative Colitis and man I'm glad this is coming but damn. I could've used this about two years ago when I was Diagnosed
As someone with MS I really hope this becomes an actual reality
Would love to hear an update on this, because if it works it would revolutionize healthcare
As someone with Crohn's and Pyoderma. Also having a little sister with MS. I might cry at even the smallest amount of hope this supplies.
I just had a look at the sources you provided. These are some high quality primary sources, and you represented them faithfully! Great work!
I think it'd be awesome for me to stop being allergic to the cat I live with, but I can only imagine the excitement of this development for people with more severe autoimmune disorders!
I have a cat allergy too, I’m with you on that one.
We already have ways to make allergies less severe -- a long series of injections, or for some allergens a long series of tablets you can put in your mouth, to gradually expose your body to increasing doses of the allergen and train your body to react less. You can ask a doctor about sublingual immunotherapy if you're interested -- I think they have it for cat allergies.
Doesn't work for autoimmune diseases, though. It's great news that they're making progress on that front. (At least in mice! What works for mice doesn't always work for humans.)
As someone with RA and SLE, its hard to currently medicate because many meds are counter to each other, so having both is a double whammy. Even if i could only 'cure' one of them, it would make treating the other easier and more effective.
Very useful for countering autoimmunity and donor rejection.
Wouldn't this also work for organ transplants, to specifically subdue immune response targeting the foreign organ instead of a wide suppression of the immune system?
Oooh, that's possible!
Yeah it could. You may make this for everything, even for foreign objects like virus antigens. The principle is pretty easy to do for many things but I am sure it has some limitations like how vaccines have. For some reactions this may be ineffective or have low effectivity than others.
I think it would have to target a great many different antigens, and a different set for each donor-recipient pair. My guess is that it won't be possible for some time, and even then, at great expense. A treatment for a specific autoimmune disease in which all patients basically need the same tagged protein is far more feasible. This is a very exciting development!
That was my first question to. Couldn't you then transplant a human head no problem.
@@zombie_snax The reason why human head transplantation is pretty difficult is first brain cells dies pretty quickly second you have a lot of things to sew veins arteries and nerves especially. Spinal cord nerves especially known for difficult to heal. Therefore organ rejection is not one of the reasons why it is pretty much impossible right now. Basically we have never come that close to worry for organ rejection
A cure for Multiple Sclerosis would indeed be wonderful!
I just wanna say thank you for mentioning type 1 diabetics in a factually accurate way. Theres so much misinformation and i wanna let you all know it means a lot to at least 1 type 1 diabetic
I used to have an autoimmune disease called ITP… though I’m in remission now, this makes me happy.
How did you go into remission?
@@Stella_9517 idk, it honestly just happened… I was just a kid at the time
I hope they do a trial for EoE. I’d jump to be part of that in a heartbeat. It’s such a horrible painful invisible disease to live with. This video gives me hope that maybe someday there might be a way to ease the pain for me and people like me.
What is EoE?
@@VizzyInks Eosinophilic Esophagitis. It’s an autoimmune disease where the eosinophil white blood cells build up in the esophagus in response to food. It causes:
* Difficulty swallowing
* Food getting stuck in the esophagus after swallowing
* Chest pain
* Backflow of undigested food
* Difficulty eating
* Vomiting
* Abdominal pain
* Poor growth, malnutrition and weight loss
Oh god, I go through horrid bouts of eosinophilia, generalized super high levels of eosinophils that don’t even respond to steroids. I’m so sorry, I know that EoE is awful, and I feel your pain.
I love this kind of good news. If it's a bit late for me, I hope it will help a lot of people in a near future.
Why is it late for you? 😢
@@VizzyInks I had my thyroid removed following an autoimmune condition. It won't grow back, sadly.
Perhaps for osteoarthritis, from which I also suffer and which is on the autoimmune spectrum, there can be a "vaccine"... the future will tell.
This is amazing!!! I really hope this gains traction because it would change sooooo many people’s lives!!
I'm so happy to hear this!!! I have systemic sclerosis sine scleraderma, which isn't fatal unless it effects the lungs or heart and I was just diagnosed with lung disease, so this can't come fast enough! 🥳🥳🥳
Hank said about his lymphoma diagnosis that it was the best year in history to be diagnosed - meaning that every year brings advancement in treatment. I can confidently say as someone whose chronic autoimmune diseases developed only a couple years ago, this is the best year in history to have an autoimmune disease. I'm so excited about the idea of not fearing gluten contamination, and I hope this means that rheumatoid arthritis could also go into remission.
This is so huge! Wishing luck to everyone waiting and hoping now!
I hope this turns out to be fully viable. I've got relatives wih Ehlers-Danlos who could really take advantage of it!
I don't think it will. Ehlers-Danlos is a genetic disease, not an autoimmune disease.
Ehler-Danlos is not an autoimmune disease this wont have any effect on that disease. It is purely genetical and there are some gene editing research in pre-clinical phase that can potentially cure it completely if they can find every mutation that causes it. FDA is very slow at approving gene editing treatments so there is only limited life-threatening genetical diseases that is actively used to treat right now such as SMA,spinal muscular atrophy etc.
@@IsYitzach Well, crud. Turns out I misremembered what I was told about it. Appreciate the clarification.
@@exosproudmamabear558 Gene editing overall will be very helpful for a multitude of things. Coupled with vaccines and and forget vaccines, we'll definitely be making some serious headway in the disease issues that plague use as a species.
That's really cool. And it sounds like it could treat allergies too? That's a huge amount of suffering that could one day be eliminated.
I would give up both of my legs if it were to mean that I didn't have allergies anymore.
If you have allergies you could just walk it off.
Profound life-changing news. Thankyou...
I love to see this! I hope this turns into lots of good treatments for people. Maybe one day this could help combat my eosinophillic esophagitis.
Thank you for the date stamp when discussing “current” research.
These are fantastic developments! Autoimmune issues are so debilitating; it’ll be wonderful to have better ways to treat or even cure them!
Hmm, are there _pathogens_ that exploit this immune calming pathway?
If they could figure out how to hijack existing p-Glu/p-Gla tags or somehow make their own, maybe? Spooky thought, but also seems like a tough route given the need to generate sugars that might well be host-specific.
Sounds like a very good question. Pathogens are a lot better at biology experiments than we are -- they've been running bacteria-sized experiments since the beginning of life on Earth. If they can't do it, it must be fiendishly difficult.
This makes me extremely happy to hear as someone with a chronic autoimmune condition
Love the Film date callout, thanks!
Daaaang! That sounds fantastic! We need more of these hopeful news. Thanks scishow!
I saw a video recently that put forth that maybe our sometimes overly aggressive immune systems that result in autoimmune disorders might have arisen during the Bubonic plague that ravaged Europe in the Middle Ages. It noted that maybe if someone had a really aggressive immune system, they might have a slight, but significant chance of surviving, and so be able to pass that characteristic on to their offspring. Interesting concept!
I developed an auto immune disease after getting COVID. The specialists are still trying to bail down what exactly I have as there are too many diverse symptoms.
Anyone else have this post COVID?
I haven't had covid (touch wood), but it's quite common for a virus to trigger autoimmune disease in people who are susceptible, unfortunately 😔
@@musingwithreba9667 Yup, I recently developped psoriasis shortly after getting the flu. Go figure.
I developed a condition called POTS, essentially your blood vessels don't do their job properly so you get a high heart rate, dizziness, blood pooling in hands/feet, fainting in some cases.
Also lots of people have been developing MCAS after Corona, which I find strange but the virus must have dysregulated the immune system in a way that causes that issue
@@gaellemat ugh....sorry! I've had psoriasis since I was a baby. It's not fun.
@@aaronm51921 my gosh that's so scary! Is there any treatment?
As someone who doesn't have any autoimmune disease, I still think this is pretty neat. Good job science!
Celiac reporting in, this is incredibly exciting; i grew up eating stuff that we later discovered i cant eat, so if this works, i’ll be able to eat the childhood comfort foods, lol
I have an uncommon autoimmune disorder and I know it'd take ten or more years to get a treatment like this for it, but it'd be a wonderful thing.
Wow ! This info is extremely important. Good job to the narrator.
Wow, this should be big news, glad this channel is talking about it.
It would be amazing to see if this could apply at all to mast cell issues. I have horrid mast cell activation and really there’s not much you can do outside of our current treatments. Anything above OTC allergy meds are so expensive and not covered by insurance there’s no way…
Yo, this is such a huge step towards relieving transplant recipients, cancer patients, and people with autoimmune diseases. I'm looking forward to the updates
Got diagnosed with MS this year. I hope this works as a treatment; I know it’s perhaps too optimistic but this looks interesting!
Same same!
As the mother of a child with T1D, this wonderful to see. I hope the trials all go well!
My mother has severe hives and rashes caused by both stress and adverse reaction to food colorants... not being able to share little snacks or drinks seems like a silly thing to be sad about, but I'd love to see the day I can share a candy bag with my mom without worrying about her health. This could change everything for so many people...
This is so cool!! I have type 1 diabetes and so I always love videos like this, so interesting and hopeful how medicine is improving!
THIS IS ABSOLUTELY EXTRAORDINARY!
Interesting video! As a small hint/feedback I suggest adding a ~0.25s pause between sentences. It's nice to have a rapid video, but it's also a little exhausting hearing sentences without natural break.
Thanks to all the people working on this kind of cures and vaccines... Really thanks a lot and hopefully it is released as treatment soon for other autoimmune disorders. Hopefully for immune thrombocytopenic purpura
As a Celiac girli le from a Celiac family, this is literally the best news we could have - here's to successful, large clinical trials, widespread distribution, and cheap/free access!!
As someone with celiac and potentially an autoimmune form of hypopituitarism, I'm so on board with this!
Oh man this is the most exciting thing I have heard in a long long time!!
As a person with a body, this will help me live!
Omg I hope this is made public soon
You forgot to mention allergies, and also eczema. In my reading I've run across the notion that eczema is an allergy, but if it was, then the Zyrtec I take daily to allow me to live with cats would have prevented the eczema. Or the type-2 antihistamine in the meds that reduce stomach acid would have treated it --- but neither was true. Sure, there is "allergic dermatitis," and maybe antihistamines help that type, but they don't do a bloody thing for "atopic dermatitis," TRUE eczema.
I already had mild eczema around my ankles at the time I got my 3rd COVID19 shot, the "booster." But 6 weeks after taking that booster, my eczema went from annoying around my ankles to whole-body itching that rarely let me get more than a couple hours sleep at a time, and resulted in scabs all over my body, from all the scratching -- it was like having millions of fleas all over my body. The mRNA vaccine made my immune system start attacking ME. I'm definitely NOT an antivaxxer, but I'm not sure I'll take another mRNA vaccine, given the mayhem and agony that the booster caused me. I've had COVID twice, and I'm glad I didn't die of it... but itching like that made me not want to live at all!
So I might be able to lose my allergies, and my mother might be able to lose her arthritis and people with second-hand organs might be able to have them put on a white list? Really looking forward to seeing how well this therapy works in humans.
Has this been tested as a replacement for anti-rejection medication for people with limb/organ transplants? I feel as though this would be a far better alternative to the autoimmune suppressants and would likely have a higher success rate without the downsides of immune system suppression
I’ve got a handful of autoimmune diseases, this would be life changing for me 🙏🏼
as someone with celiac disease, this would be absolutely incredible!!
So cool! Allergies and autoimmune diseases are messed up. Being able to remove them would be great.
This is amazing news indeed. Giving hope to people with autoimmune deseases and after transplantations.
This would be so incredible if with a transplant surgery, they would give a vaccine teaching immune system to accept a transplanted organ.
This is soooo exciting
As a Type 1 diabetic, the idea that one day I might be able to get a pancreas transplant is inspiring!
This is truly amazing :O
Where can I join the studies for this? I'm tired of being allergic to everything.
Sounds like an allergy solution
Awesome we need it quickly alot of patients are suffering
Wonder if this would resolve ITP.. this is groundbreaking for autoimmune diseases! Gonna share with the group I joined from my own experience.
In a world constantly beset by terrible news, this kind of stuff is the light in the darkness that reminds me that humans are awesome and really do want to help each other.
Yesterday, I was mentally theorizing that medical science should develop a treatment that turns off a specific autoimmune response. 24-hours later this UA-cam video pops up. This keeps happening to me. I think of some new concept and within 3-days UA-cam is presenting it. Either I have the ability to predict the future or UA-cam has the ability to read minds.
Third option: you've just cherry-picked a few specific coincidences and failed to notice the vast majority of your thoughts don't appear on youtube and the vast majority of the videos in your feed aren't something you thought about recently.
That was already factored in.@@aysnov
Baader-Meinhof phenomenon or frequency illusion
I've thought about precognition for a while and I think it's actually a product of the brain picking up on subtle cues that aren't actively registered by the subconscious. Like knowing it will rain, maybe one notices pressure changes that we don't think about, or guessing someone is sick, might of smelled it with out realizing. I think the same happens when we see patterns of new or recently discovered topics circling around. Perhaps your brain picked up on some other "context clues" that either guided you to this video, or other things in the field have been going on, so it was likely for scishow to do a video on it.
It could also just be coincidence. That's always a possibility that we forget, because we're pattern seekers and tend to think nothing is random.
Icr the name, but I heard an idea once I liked the sound of. (Besides the other replies with valid suggestions too, of course.)
The idea went: sometimes conditions are conducive to making certain connections. Like if enough people sit in traffic, someone is likely to get annoyed enough to put sustained effort into planning solutions.
Altho wherever I heard it from, the context was more about how scientific discoveries / hypotheses and theories are explored around the same time by different peoplpe in the same field.
I caught cold sores 10 years ago and ever since then, my immune system just attacks all random parts of me from random internal and environmental triggers. It also has an exaggerated response to regular pathogens like treatable fungal, bacterial, and viral infections. This even includes medications for the infections!
All this overreacting of the immune system simultaneously fatigues it, CAUSING more opportunistic infections to happen.
None of these are allergy responses either. Doctors are really confused as to "what to call this disorder," so they choose NOT TO TREAT IT because it is a disorder that "exists but doesn't have a known pathogenesis," so they can't put a medical code on it to prescribe treatments. They're also uninterested in studying it because it is complex and maybe an orphan disease.
I hope this treatment can help people like me too. (Honestly, I'd probably have a reaction to the vaccine to stop the reactions. lol)
Anybody else out there with this issue?
They... they can't even code it as like 'idiopathic systemic immunodepletion' or something?! Wtf.
Are they even *trying* to help you as a human person with a body and a life to live.
@@MxVerdaArt No. They aren't. Prior to the pandemic, I visited NIH, a bunch of specialty hospitals on the East Coast. Some of the most prestigious medical institutions in the country.
All of them acknowledged something was wrong, and then tried to gaslight me by saying it was psychsomatic. I have never seen so many hospitals lose specific bloodwork that indicates the serum levels for the deficiency, but they all managed to. Thankfully, I kept copies (bc of electronic records), and would keep resending, but was just ignored. They even tried to lock me up once.
Then the pandemic happened, and people started having Long COVID symptoms, and the medical establishment had to acknowledge that viral infections can cause onsets of genetic issues this way.
Now doctors know the truth, acknowledge something is wrong, and turn me away specifically because the case is complicated and the only known treatment currently is gammaglobulin, and they don't want to fight the insurance company for it.
Look up natural killer cell deficiency syndrome if you're interested in knowing more. It usually has a childhood onset but more people are undiagnosed and developing it in adulthood. The doctors studying it will only diagnose it if you have one the genetic defect abnormalities, but it's so newly discovered that they haven't FOUND all the markers yet. If you don't have one of the 3, they are like, "You have it somehow. But we can't put it down bc the diagnostic criteria requires a genetic marker."
Clinically and blood serum-wise, I meet all the criteria. They've left me like this with no treatment for 4 years now. Before that, I was on gammaglobulin which helped. They took me off. They also took me off my antivirals and I had to quickly find a new doctor before I developed seizures and brain inflammation.
Doctors are just checking out on complex patients. I pass on the word whenever I can: get out of the US if you are able. Learn about your conditions and change your lifestyle to hold you over. Find a foreign doctor and a health advocate (preferably male bc of sexism in medicine) as soon as you can.
@@Sidera17 woah that's insane I'm sorry you gotta deal with such a headache:(
Out of dumb curiosity, could it be related to the Herpes virus? I know they cause cold sores and also are good at hiding from your immune system so I could imagine it like a messy game of cat n mouse. Probably not though I'm just shooting blindly with my ignorance
Thanks!
@2:08
Phenomenal news, especially for people with diabetes and intestinal issues; the liver effectively being the judge of what gets attacked by T Cells or not is yet another reason why it has the distinct ability to regenerate -- why no other organ can regenerate still eludes us however.
Also, as someone who has a decent knowledge of human anatomy, that inverted liver is pretty cursed.
Just a guess, but I'd say it could be likely others don't because of the "spore" rule. If the building blocks of existence take "credits" from being complex structures, then if something isn't outright detrimental to survival and procreation, why "waste" credits on it? Specific organs/tissues having the ability to be resilient in many forms are generally super useful, but to be so complex to have many redundant systems and regeneration would take even more DNA/genetic credits so to speak.
Effectively, it's a flaw in not being designed, but simply a product of circumstance. Gene editing and medicine overall are basically us working to design ourselves. Fixing all the many holes left by evolutions inability to really care.
@@vixxcelacea2778
l can at the very least think of the heart and even some critical areas of the brain (think the amygdala, hippocampus and such) where their failure would be detrimental to survival and procreation, if not a few unique others like the pancreas, so l don't think that's quite it.