Genius CUBANE Synthesis by Nobel Laureate & Overpriced Drugs | Organic Chemistry (MacMillan)

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  • Опубліковано 6 вер 2024

КОМЕНТАРІ • 55

  • @totalsynthesis
    @totalsynthesis  Рік тому +11

    Thanks for watching!
    Massive thank you to all channel supporters!
    instagram.com/totalsynthesis_official/; www.patreon.com/totalsynthesis

  • @agiantdinosaur
    @agiantdinosaur Рік тому +30

    Finally... enough classes in biochemistry, organic chemistry, and medicinal chemistry and I can FULLY comprehend this video. Solid video as always.

  • @TheDeltaboss
    @TheDeltaboss Рік тому +182

    Tom I know you'll be watching this.... You should be writing your thesis.

    • @maley_malo8726
      @maley_malo8726 Рік тому +20

      Don’t listen to him, Tom! You have a plenty of time

    • @PoseidonDiver
      @PoseidonDiver Рік тому +16

      That's right Tom, plus, the sooner you fall behind the more time you have to catch up!

    • @ExtractionsAndIre
      @ExtractionsAndIre Рік тому +100

      I finished a chapter this week ok i'm on a breakkkkkkkkkkkkkkk

    • @keithcarpenter5254
      @keithcarpenter5254 Рік тому +5

      ​@@ExtractionsAndIre 😂 Have you got an alert set up for any video with cubane references?! Lol

    • @ExtractionsAndIre
      @ExtractionsAndIre Рік тому +19

      @@keithcarpenter5254 No I just like cubane videos! And this is a good one!

  • @eselarsch88
    @eselarsch88 Рік тому +14

    Hypercubane looks like straight out of the Journal for Immaterial Science.

    • @totalsynthesis
      @totalsynthesis  Рік тому +3

      Thats just what I thought, lol. Need to read into those predictive calculations and see if its interesting enough for a future video

  • @That_Chemist
    @That_Chemist Рік тому +8

    👀

  • @PoseidonDiver
    @PoseidonDiver Рік тому +5

    Ohhh this is gonna trigger @ExtractionsAndIre
    🤣🤣🤣🤣🤣

  • @edced_
    @edced_ Рік тому +7

    i am finishing my first year in biomedical sciences, do i understand everything in this video? no. Does it make me want to continue studying so that i can understand everything? absolutly.
    Great video

    • @totalsynthesis
      @totalsynthesis  Рік тому

      Amazing, thats the spirit!

    • @gio9789
      @gio9789 Рік тому +2

      i'm finishing my first year in farmaceutical chemistry. i didn't understand much either. but it still fascinates me

  • @rileymerson8781
    @rileymerson8781 Рік тому +12

    I’m just waiting for Cubane drugs🔥
    Cuba-cocaine probably goes hard
    Or 6 step LSD synth you uploaded x cubane

    • @ghostwriter1415
      @ghostwriter1415 Рік тому +1

      So there really is no plausible, chemical pathology for any physical/psychological illness? If a molecule look's neat, like a house, see what it does in a mouse?

    • @totalsynthesis
      @totalsynthesis  Рік тому

      Lol

    • @pucky8231
      @pucky8231 Рік тому +1

      get a little cubestasy ?

    • @rileymerson8781
      @rileymerson8781 Рік тому +2

      @@pucky8231 the world just isn’t ready for cuba-methamphetamine

    • @Flesh_Wizard
      @Flesh_Wizard 10 місяців тому

      ​@@rileymerson8781 *tweaks geometrically*

  • @SJCooper
    @SJCooper 4 місяці тому +1

    Awesome job on the video! Really beautiful chemistry here!

  • @Breakingcraft
    @Breakingcraft Рік тому +11

    You cant talk about Cubane without mention the australian guy!

  • @ErulianADRaghath
    @ErulianADRaghath Рік тому +12

    You know, with how difficult Cubane is to synthesize, we should call it Cu-Pain instead lol

  • @flowerpt
    @flowerpt Рік тому +2

    Wild. I had no idea about these structures. No doubt this is gonna cost me 4 hours of reading time this weekend! Great vid. Oh, plus Argentina.

  • @multiarray2320
    @multiarray2320 5 місяців тому +2

    waiting for nilered to synthesize cubane :)

  • @nathantang9964
    @nathantang9964 Рік тому +1

    Glad to see the channel growing and that you have more time to make videos

    • @totalsynthesis
      @totalsynthesis  Рік тому

      Thanks man! Unfortunately Ive been quite busy recently but hope I can get back to the same pace in summer

  • @joe47771
    @joe47771 24 дні тому +1

    nothing beats bucky ballz

  • @adrianpip2000
    @adrianpip2000 Рік тому +1

    Still waiting for someone to come up with nice synthetic routes to make polysubstituted cubanes. I have a specific motif I dream of trying to make, but the benzene variant is 1,2,4,5-tetrasubstituted. While I have a few half-arsed ideas based on digging in some old literature, I doubt they would work tbh.

  • @nathantang9964
    @nathantang9964 11 місяців тому +1

    Do you have a source for the quasi favorskii hypothesis?

    • @totalsynthesis
      @totalsynthesis  11 місяців тому

      Source is Bredt's rule, haha

    • @totalsynthesis
      @totalsynthesis  11 місяців тому

      Quick search gave this for example: www.studocu.com/in/document/pondicherry-university/advanced-organic-chemistry/quasi-favorskii-rearrangement/46811769

  • @rufusjordan7733
    @rufusjordan7733 Рік тому +1

    I saw a question about cubane in a chemistry Olympiad.

  • @bdnugget
    @bdnugget Рік тому +1

    Excellent vids m8

  • @NoNameAtAll2
    @NoNameAtAll2 Рік тому +2

    "friend deuterium" = NileRed
    cody's lab, you lost your chance when you had it

  • @phanomtaxskibididoodoo
    @phanomtaxskibididoodoo Рік тому +2

    Cubane sounds like a rappers name.

    • @petevenuti7355
      @petevenuti7355 Рік тому

      I thought it was the guy from Shark Tank , Mark Cubane 😜

    • @Flesh_Wizard
      @Flesh_Wizard 10 місяців тому

      I was thinking grunge
      Kurt Cubane 😂

  • @irgendwieanders2121
    @irgendwieanders2121 Рік тому +1

    Nein, nicht wirklich...
    Ein Österreicher.
    Uni oder Rosensteingasse auch?

    • @totalsynthesis
      @totalsynthesis  Рік тому

      Close! But DACH region is correct

    • @irgendwieanders2121
      @irgendwieanders2121 Рік тому

      @@totalsynthesis Warum meine Antwort darauf gelöscht werden mußte, erschließt sich mir überhaupt nicht...

    • @totalsynthesis
      @totalsynthesis  Рік тому +1

      @@irgendwieanders2121 Wait what? I didn't delete anything. I only delete comments on my psychedelic videos which attract bunch of spamming fake accounts selling shrooms

  • @laslaw9887
    @laslaw9887 4 місяці тому

    ua-cam.com/video/uQ3YLRpaMlU/v-deo.html
    bycyclopentanes u mean?
    just say "propellanes"

  • @alllove1754
    @alllove1754 Рік тому +1

    Very exciting to see new ways to this! I'm hoping that it's obvious use in quantum machines is soon