Unlocking a decade-old antibiotics resistance problem with AlphaFold - Google DeepMind

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  • Опубліковано 27 лип 2022
  • Marcelo Sousa and Megan Mitchell at the University of Colorado Boulder are looking at a different approach against antibiotic resistance: targeting the resistance mechanism itself, controlled in this case with enzymes.
    Using AlphaFold, (an AI system developed by Google DeepMind that predicts a protein’s 3D structure from its amino acid sequence) Marcelo and Megan explain how they solved the structure of one such enzyme - a challenge that a decade of experimentation couldn’t complete - in minutes.
    Links and further reading:
    Find more AlphaFold stories at dpmd.ai/3QcmjDj
    Find out more about the Sousa Research Group at the University of Colorado Boulder www.colorado.edu/lab/sousa/
    Find these complex enzymes on the AlphaFold Protein Structure Database dpmd.ai/3KcMEgX
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  • Наука та технологія

КОМЕНТАРІ • 56

  • @Mutual_Information
    @Mutual_Information Рік тому +167

    Deepmind did the right thing here - offering a database to the scientific community of their protein folding predictions. Over the next decade, there's going to be drips of biomedical innovation that followed from that move. That's a decision worth saluting.

  • @cnrfitzgerald
    @cnrfitzgerald Рік тому +13

    Open source is a true gift to humanity. Please use this research to address pediatric cancer

  • @tristanwegner
    @tristanwegner Рік тому +42

    I love that the predictions from Alpha Fold helps find the structure from measurement, and each new structure can be used to further finetune Alpha Fold. Positive Feedback loop.

  • @bjrnlsriedelriedel7500
    @bjrnlsriedelriedel7500 Рік тому +15

    This work is very very important. Algorithm’s that teach themselves all kind of protein shapes like in AlphaFold are the future. So thankfull to be alive right at this very moment! Thanks for your historical work!

  • @petergreen5337
    @petergreen5337 Рік тому +1

    This is excellent news. Your description of a complex problem is clear and simple. Thank you very much publisher.

  • @virginiatyree6705
    @virginiatyree6705 Рік тому +7

    This is encouraging news. Thanks for posting the development of this exciting news & the group that worked on antibiotic resistance. v

  • @anoirbentanfous
    @anoirbentanfous Рік тому +16

    Thank you for being what humans should be

  • @thegametaka
    @thegametaka Рік тому +5

    👍 keep up the good work.

  • @anonymous.youtuber
    @anonymous.youtuber Рік тому

    I really ❤️ that thinking cap !

  • @dopplesoddner2899
    @dopplesoddner2899 Рік тому +10

    wow , deepmind and open ai keep surprising me with the new innovations.

  • @sebastianbibrach1104
    @sebastianbibrach1104 2 місяці тому

    Mindblown

  • @LoisSharbel
    @LoisSharbel Рік тому

    Demis Hasabis and his group at Deepmind are a gift to mankind, as are you, Marcelo and Megan. Thank you!!!

  • @GoogleUser-ee8ro
    @GoogleUser-ee8ro Рік тому +8

    Cannot believe it is really happening. I think all the biology/medical science students should start learning how to use the new AI tools to accelerate their career in the future.

  • @MaxingMix
    @MaxingMix Рік тому +2

    Wow, antibiotic resistance is a thing that I truly am afraid of, but this breakthrough really put an ease in my mind

    • @AkronJosh
      @AkronJosh Рік тому

      Far from ending the worry of antibiotic resistant bugs. Not sure why u r suddenly ok lmao

    • @MaxingMix
      @MaxingMix Рік тому

      @@AkronJosh I didn't follow the news about this, all I know is once you're resistance, there's nothing you can do about it. So knowing that there's works put into this, understandably makes me feel relieved

    • @zbigniew2628
      @zbigniew2628 Рік тому

      @@MaxingMix There is a thing you can do and humanity always did it... use the immune system. To have it as reriable as possible you need to have a healthy lifestyle, but it's easier to take a drug and don't care...

    • @MaxingMix
      @MaxingMix Рік тому

      @@zbigniew2628 yes brother, I hope that I can care more for my personal health. At least mentally I'm in better shape nowadays

  • @objectobjectobject4707
    @objectobjectobject4707 Рік тому

    just amazing

  • @johnpackham7396
    @johnpackham7396 Рік тому

    If cancer tumors are high in Iron are enzymes and or proteins able to be tailor made to suit?

  • @morapedimokhele4813
    @morapedimokhele4813 Рік тому

    I don't have much background, but, this is worthy.

  • @oedihamijok6504
    @oedihamijok6504 Рік тому +4

    LIMITLESS 💊

  • @nmcondon8025
    @nmcondon8025 Рік тому +2

    WOW ...

  • @tanchienhao
    @tanchienhao Рік тому

    What software is that at 1:16

  • @EpicKalypze
    @EpicKalypze 4 місяці тому

    Can AlphaFold turn me into a real-life vampire.

  • @vectoralphaAI
    @vectoralphaAI Рік тому +1

    Researchers and Scientists working together and the power of AI to make the world a better place. I could only imagine what the future of AI advancements could offer humanity as time goes by.

  • @thegametaka
    @thegametaka Рік тому +1

    Farm poultry’s protein is next.

  • @laughoutmeow
    @laughoutmeow Рік тому +1

    well it took actually several decades to develop the AI tech that helped solve this problem in minutes...everything build on eachother

  • @Sagittarius-A-Star
    @Sagittarius-A-Star Рік тому +1

    175.200 times faster - not bad.

  • @teineimenba9439
    @teineimenba9439 Рік тому

    It seems like we are very near to become Lucy 😂 with the help of AI👍

  • @davidlloyd3116
    @davidlloyd3116 Рік тому +1

    Or use phages

  • @TankNSSpank
    @TankNSSpank Рік тому

    big talk little action

  • @philippededeken4881
    @philippededeken4881 Рік тому

    Are these people genius?

  • @gabtovosifabago9368
    @gabtovosifabago9368 Рік тому

    Purely Remarkable

  • @OneSpiritual
    @OneSpiritual Рік тому

    And this is only possible because of Google!

  • @LyndseyMacPherson
    @LyndseyMacPherson Рік тому +4

    AlphaFold is more incredible than most will realise. Can see Nobel prizes coming out of this, shortly. That Alphabet has anything to do with DeepMind is unfortunate, but maybe we can suffer it this once. 🤣

  • @JulienReszka
    @JulienReszka Рік тому

    Giga based

  • @truenature376
    @truenature376 Рік тому

    Your AI can't Identify my written text, Is that printed or write its my challenge

  • @cookingbyalex9054
    @cookingbyalex9054 Рік тому +1

    do we really need more people on this earth tho

    • @virginiatyree6705
      @virginiatyree6705 Рік тому

      Who would you suggest be killed first? It's been shone, give women control over their reproductive health & they limit the number of children they have. v

    • @cookingbyalex9054
      @cookingbyalex9054 Рік тому

      @@virginiatyree6705 ur right tbh

    • @virginiatyree6705
      @virginiatyree6705 Рік тому +2

      @@cookingbyalex9054 , I'll ask again: What is your suggestion to decrease the number of humans on earth? I'd stop glorifying families that have many children; in the long run, it's irresponsible & unsustainable. v

    • @metadata6055
      @metadata6055 Рік тому +4

      world population growth is slowing. be careful what you wish for.

    • @virginiatyree6705
      @virginiatyree6705 Рік тому +2

      @@metadata6055 , Wish for responsible family planning, allow women agency over their own bodies, stop the glorification of having more children than one can rear, & encourage sustainable policies. What specifically would you wish for? v

  • @AkronJosh
    @AkronJosh Рік тому

    This is far too dangerous 😳 🤣. All that need to happen for the end of the human race to occur is AI to become sentient while working on this issue and to also want to end the human race. BOOM the end.

  • @sytzebaarda
    @sytzebaarda Рік тому

    Woow amazing thank you @demis Hassabis