Bruker D8 Venture in the Center for Structural Biology: Hands-on demonstration

Bruker D8 Venture: Hands-on demonstation by Dr. Matt Benning, Senior Application Scientist, Bruker AXS
Recorded April 9, 2019
A demonstration of the use of the D8 Venture system in the Biomolecular Crystallography Facility in the Vanderbilt University Center for Structural Biology.
Other videos provide an introduction to the D8 Venture and details for setting up and collecting diffraction data and practical examples of structure determination using the system and details of how to process synchrotron data using Proteum 3.
The D8 Venture provides exceptional in-house X-ray diffraction capabilities to researchers at Vanderbilt University. The system is equipped with an extreme brightness Excillum D2+ MetalJet X-ray source employing a liquid gallium alloy jet anode capable of accepting significantly higher power loads than conventional solid metal targets. The liquid gallium anode allows for extremely small electron spot sizes provided using a LaB6 cathode and an electronically controlled focusing coil. A HELIOS MX optic focuses the X-ray beam with multiple options to control beam divergence according to crystal size and unit cell parameters. Crystals mounted on the kappa-axis goniometer can be presented to the beam in any orientation to provide complete coverage of the reciprocal lattice. A PHOTON II charge-integrating pixel array detector allows for low noise, shutterless data collection. The facility is available for both macromolecular and small-molecule structure determination.
The D8 Venture is supported by an award from the Vanderbilt University Trans-Institutional Programs.
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