Mismatch repair explained in a way you will never forget again!

This video illustrates the mechanism of mismatch repair mechanism in DNA damage.
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[@akshitadixit1011]

The whole series is so helpful thank you so much

[@DrArindamGhoshBiochemistry]

Glad to help Akshita. Keep in touch 😃

[@deepikamahto8039]

Nicely explained 👌 thank you 😊 sir
I am preparing for CSIR NET Exam .
And this video is so helpful. 🙏

[@polinagavrikova9346]

Many many thanks from Vienna!

[@DrArindamGhoshBiochemistry]

Greetings 😇

[@aqsaashraf5035]

Helpful video, Thank you so much 😇

[@DrArindamGhoshBiochemistry]

Most welcome ❤️

[@leidygoldstein6767]

Thank you so much!

[@DrArindamGhoshBiochemistry]

Most welcome 😃

[@deepprabha]

thank you so much

[@DrArindamGhoshBiochemistry]

Welcome Deep

[@aditiverma3386]

Thank you sir... Great lecture 🙏

[@DrArindamGhoshBiochemistry]

Thanks ☺️

[@minabassam8268]

Thank you soo much for these great videos🥰♥️

[@DrArindamGhoshBiochemistry]

Most welcome 😁

[@meditationmusic1523]

Thank you so much sir.

[@jum833]

Thank you so much .. good lecture 😊😊

[@DrArindamGhoshBiochemistry]

Most welcome 😃

[@shreyosibanerjee8961]

Thank you sir 😊

[@akshitadixit1011]

Sir, Is there any enzyme which is responsible for parent strand methylation and which is the base between them particularly methylated ?

[@prabachanthapa4710]

Sir I think DNA Pol 1 is used instead of DNA Pol 3

[@DrArindamGhoshBiochemistry]

Pol 3 is main polymerase. Pol1 is for proof reading...

[@mgciii030jayasree.k2]

Thank you so much sir

[@DrArindamGhoshBiochemistry]

♥️

[@mansikesarwani900]

Best explanation sir ....

[@DrArindamGhoshBiochemistry]

All the best for exam!

[@prabindebbarma4220]

Sir very very thank you this is very easy to learn ❤❤

[@DrArindamGhoshBiochemistry]

Most welcome 😃

[@middlewayers]

How do we know that the original error is on which strand?

[@DrArindamGhoshBiochemistry]

original error is always on the newly synthesized strand as parent strand alread had its proof reading post replication

[@middlewayers]

@@DrArindamGhoshBiochemistry thanks for replying

[@meowmeow1081]

Hi Dr Ghosh, I have a question: What if the GATC sequence is very far away, wouldn't it 'waste' a lot of energy to reform that whole new segment? Thanks!

[@DrArindamGhoshBiochemistry]

you are absolutely right if that is the situation. But the genome is designed in such a way that there are GATC sequence in every few checkpoints 😬 so that issue is taken care..

[@meowmeow1081]

@@DrArindamGhoshBiochemistry Thanks for getting back to me and thank you for making this topic so much more interesting!

[@DrArindamGhoshBiochemistry]

Most welcome 😃

[@bawarshakawa3884]

@Dr.Arindam Ghosh Hi can you please tell me urgently how gene mutations in DNA mismatch repair arise ? and what are the genes ? Please and if you can can you reccomemdn a diagram.

[@chilubazimba1406]

Wow thanks sir very helpful for my exam

[@DrArindamGhoshBiochemistry]

✅😁

[@ipsitamishra1308]

U r great sir..it became too easy..sir full form of mut is what?

[@DrArindamGhoshBiochemistry]

Mutation

[@ipsitamishra1308]

@@DrArindamGhoshBiochemistry tysm sir😊😊

[@DrArindamGhoshBiochemistry]

🙂🙂

[@ipsitamishra1308]

@@DrArindamGhoshBiochemistry sir may i contact you for my doubts because my exams are coming...

[@DrArindamGhoshBiochemistry]

Feel free to post your doubts In the comments section. And for contact details check the video description

[@shivani4744]

Ber also removes the mismatched bases then whats the difference in proceduere ?

[@DrArindamGhoshBiochemistry]

Mechanism are different and MMR only removes the specific mismatch ones. This removes few upstream and downstream ones and is a more radical method.

[@abczxc1239]

Thank you soo much sir

[@DrArindamGhoshBiochemistry]

Most welcome

[@mmd123king6]

@@DrArindamGhoshBiochemistry doctor are all of the proteins come from dna or are formed whenever is needed like dna is damaged the body gets a signal and then they would form the proteins does the proteins come from stored in the dna or from other parts if the body?