Lac Operon

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  • Опубліковано 29 січ 2008
  • NDSU Virtual Cell Animations Project animation 'Lac Operon'. For more information please see vcell.ndsu.edu/animations
    The Lac Operon is an example of an inducible system of gene expression. Its default state is to be inactive. Only when the right catalyst is added to the system, in this case the sugar lactose, is the process activated, allowing the genes in question to be expressed.

КОМЕНТАРІ • 423

  • @jamesmallon1631
    @jamesmallon1631 8 років тому +469

    i really find that 3D visuals of the molecules really help my brain much much better than simple 2D squares etc. Really good video

    • @babuagnihotri5231
      @babuagnihotri5231 5 років тому

      surya grahan

    • @meghnasingh4396
      @meghnasingh4396 4 роки тому +4

      And much better than a bunch of words, especially, if not put together in a comprehensible manner !
      There's no point complicating simple stuff :)

    • @shyamamalikamalwalagee2842
      @shyamamalikamalwalagee2842 4 роки тому

      @@mdsouthcarolina6143 hiruniws

    • @tanzilaghulam9519
      @tanzilaghulam9519 3 роки тому

      100%✔✔✔

    • @Sradha_274
      @Sradha_274 3 роки тому

      Absolutely yarr... it's made me easy to understand this topic 🤟

  • @akanksha2925
    @akanksha2925 3 роки тому +45

    It was really simple and visualisation makes it simpler to understand. Class 12th (biology) students from India might find it very helpful.

    • @crochetforfun8730
      @crochetforfun8730 2 роки тому

      Hey do you wanna message one another, I’m also grade 12student( biology ) from Canada

    • @sangitathami4973
      @sangitathami4973 Рік тому

      Im from nepal

  • @shiney94
    @shiney94 10 років тому +312

    That's not true. Lactose does not bind onto the lac repressor. Lactose gets transformed into allolactose, and the allolactose binds onto the lac repressor

    • @emilioduverna4741
      @emilioduverna4741 10 років тому +34

      In three minutes would you be able to talk about the transformation of beta 1-4 linkage into beta 1-6 linkage? be fair ok//

    • @shiney94
      @shiney94 10 років тому +121

      Emilio Duverna It is possible. Or you could just extend the vid a bit more. take this as constructive criticism (rather than deconstructive criticism). My comment would help people not to get confused. imagine in an exam, if the question is asked 'what binds onto the lac repressor?' and you say 'lactose'. You would lose a mark

    • @KarthikSubramanianKrishnan
      @KarthikSubramanianKrishnan 7 років тому +3

      Super ... Can you link me to the research paper please!?

    • @komalverma5425
      @komalverma5425 6 років тому +2

      ShineyM you are right and I am agree with u

    • @kanjriwalakhadeeja4579
      @kanjriwalakhadeeja4579 5 років тому +1

      @@emilioduverna4741 yeah in less then 3 minutes I bet

  • @ShutterAuthority
    @ShutterAuthority 15 років тому +90

    very good
    thanks a lot
    I understood it very well

    • @jonasvanmieghem3024
      @jonasvanmieghem3024 3 роки тому +9

      How are you after these 12 years?

    • @zhongxina674
      @zhongxina674 2 роки тому +1

      Hey yo how are you ? My god after hustling bustling 12 years😮

    • @princeshorts3213
      @princeshorts3213 2 роки тому +13

      So 12 years ago u was a normal biology student, but now u r a youtuber with 3.76M subs
      Great

    • @takemein
      @takemein 2 роки тому +1

      Here are some notes too.
      ua-cam.com/video/YSvoid3wjbc_/v-deo.html_THE_LAC_OPERON

    • @crazyburritos7720
      @crazyburritos7720 2 роки тому

      ig this is your oldest yt comment

  • @Goldencloudd
    @Goldencloudd 13 років тому +4

    Thank you so much for posting this. I have a test tomorrow on the lac operon and stuff like this, and up until now I've been absolutely lost. I may actually not fail! Thanks!

  • @charleyjr.iriarte7428
    @charleyjr.iriarte7428 9 років тому +2

    Thank you for the teaching of the lac Oberon.
    Blessing to you.

  • @janimalia
    @janimalia 15 років тому

    These three minutes of watching is equal to 30 minutes of reading. Great material, thank you very much!

  • @DirectorAntify
    @DirectorAntify 8 років тому +10

    Really easy to understand now, I wish I discovered this video sooner!

  • @jmelendez44
    @jmelendez44 12 років тому +11

    Thank you!!!!
    So easy to understand!!!
    My professor took 2 hours "explaining" this and you totally made it make sense in 3:27 min!!!

  • @nikolaizakrewsky4406
    @nikolaizakrewsky4406 10 місяців тому

    I was just reading my textbook about this and it was going over my head and unappreciated. Watching this has helped a ton! It's really incredible and amazing how intuitive these systems are! A bunch of biomolecules doing such clever things! Awesome!

  • @Lollipopiification
    @Lollipopiification 10 років тому +6

    this is like 100x more useful then a picture and 3 paragraphs of words........ THANKS ALOT!!

  • @rvgeraz7239
    @rvgeraz7239 8 років тому +17

    this video is simply amazing thanks for uploading it .It just cleared out all my doubts…

  • @girinandhan1372
    @girinandhan1372 5 років тому

    The 3D picturization makes it easy to understand...Thank you so much for this 😊

  • @sidra7011
    @sidra7011 8 років тому +52

    Thank you so much! You've made it look so easy!! My biology teacher just gave us a worksheet and told us to learn the Lac Operon and didn't bother teaching it.

    • @zannatul23
      @zannatul23 8 років тому +3

      +Sidra Hussain LOOL trust

    • @swimsuitcookies
      @swimsuitcookies 8 років тому +1

      +Sidra Me too, that's why I'm here lol!

    • @noracox6567
      @noracox6567 7 років тому +7

      You just took charge of your own learning. That is the point. Don't wait for someone to "teach" you. You have no control. Move forward and "learn" on your own. Then you are ready to be a well-read and well-educated adult.

    • @ashleymarie8415
      @ashleymarie8415 5 років тому +2

      mine too

  • @i.gaskoid
    @i.gaskoid 9 років тому +3

    Thank you for making this easy to visualise!

  • @puneetmaheshwari
    @puneetmaheshwari 3 роки тому +4

    saw this on mute when in my online class same topic was going in and helped me a lot to understand

  • @TheJavachill
    @TheJavachill 9 років тому +71

    The inducer is allolactose rather than lactose itself, but a great visual representation.

  • @ndsuvirtualcell
    @ndsuvirtualcell  16 років тому +10

    Thank you. :) We use Autodesk's Maya.

  • @datarush1323
    @datarush1323 4 роки тому

    Very simple and perfect explanation to the complex content

  • @animalluver3616
    @animalluver3616 15 років тому

    i have a final for biology tomorrow and my teacher showed this video to us earlier in the year. it helped me so much then and it helped me so much now to refresh my mind on this topic

  • @bbmeesci5950
    @bbmeesci5950 7 років тому +1

    This is the best explanation i've seen. Thanks.

  • @andrewciuffreda7722
    @andrewciuffreda7722 7 років тому +11

    thmbs up for a video that is very helpful as a review tool

  • @shakthiyadav7205
    @shakthiyadav7205 5 років тому +2

    The best video that teach me jst before 20 minutes of my examination

  • @sizzlemydizzle81
    @sizzlemydizzle81 15 років тому

    Absolutely awesome explanation, thank you so much!

  • @emmacho2580
    @emmacho2580 10 років тому

    Such a great video!!! Thanks for sharing this!

  • @pradhumansharma9770
    @pradhumansharma9770 3 роки тому

    This is really good.
    I didnt even undsrstand what an operon is.
    But thanks to your visuals bow i got it its a part of DNA and how it works properly

  • @yummi1e
    @yummi1e 13 років тому

    Even though it's missing a few information, it was a good visualization of how the whole thing works.

  • @Warphaker
    @Warphaker 13 років тому

    Thank you for this video. Reading my notes from class doesn't make ANY sense at all but this all does!

  • @didierlauwerys8390
    @didierlauwerys8390 10 років тому

    The animation videos are very useful, thank you!

  • @letslearn2985
    @letslearn2985 3 роки тому +6

    Was really helpful
    3 D animations are immensely useful in learning biology.

  • @narymenemaouche88
    @narymenemaouche88 6 років тому

    A very beautiful demonstration thanks

  • @cianisy
    @cianisy 13 років тому +2

    Thank you for making this video. It's excellent for class instruction.

  • @magicbaby44
    @magicbaby44 15 років тому

    i personally found it very useful
    i really didn't understand the lac operon until i saw this
    thanks :)

  • @evil-robot
    @evil-robot 14 років тому

    Beautifully animated

  • @payamosman9623
    @payamosman9623 3 роки тому

    Best video ever..made it all easy..thank you!

  • @paleobc65
    @paleobc65 9 років тому +3

    really helped me with AP bio

  • @wildsunbeam
    @wildsunbeam 14 років тому

    Very helpful and well explained! Thank you very much!

  • @jenosanchez
    @jenosanchez 9 років тому +3

    This is very helpful, the best one by far!!!!

  • @michiegrl24
    @michiegrl24 11 років тому +1

    glucose decreases adenyl cyclase- reducing cAMP thereby repressing the lac operon. the purpose of the lac operon is to make glucose by breaking down lactose (glucose + galactose). when there's plenty of glucose, there's no need to breakdown lactose to get it.

  • @jubairahmedbarbhuiya7748
    @jubairahmedbarbhuiya7748 6 років тому

    I find it very useful .. it made my concept very strong. . Thanks for this video. . !!

  • @jononumbahfive
    @jononumbahfive 14 років тому +1

    I believe this "cute cartoon" presentation was intended for beginner's biology students to help them get the gist of the lac operon and its subcomponents. Saying it is "inaccurate" would be unfair and untrue.

  • @Dr3aash
    @Dr3aash 10 років тому +2

    I love the music when the vid starts lol

  • @xyzjoanna
    @xyzjoanna 12 років тому

    Just to add, it is the lac I region that encodes for the repressor, which only represses the operon in the absence of allolactose (the inducer).

  • @dhoblerahul
    @dhoblerahul 13 років тому

    thanks your video helps me really well to understand lac operon properly

  • @mrsjocelyn421
    @mrsjocelyn421 9 років тому

    Thank u for taking time to make this video

  • @Joshua-qb9ru
    @Joshua-qb9ru 2 роки тому

    wow this one is great! . straightforward

  • @banaalani7216
    @banaalani7216 6 років тому

    so helpful thanks a lot! I watched it after the amebia sister video which was so helpful as well and this one explained everything more!

  • @shilpakanjilal5210
    @shilpakanjilal5210 2 роки тому

    From india , literally ncert choked me up with their description thanks fr this 🙂

  • @Yggdrasilincarnate
    @Yggdrasilincarnate 15 років тому +3

    Really great for my Genetics revision - thanks so much! Whilst it doesn't include cAMP, or the fact that it is Allolactose which induces the system, it was great for simplifying the process so I could get my head around it. Thanks again! ^^

  • @medhapatel
    @medhapatel 13 років тому

    Thank you so much. Excellent job. .....

  • @sadiya_sehar
    @sadiya_sehar 5 років тому +1

    I have this topic almost in every sem... I always watch this video... Its just awesome..! I seriously dont go through the theory.. I will just watch this video😇

  • @Cocoabeauty12
    @Cocoabeauty12 11 років тому

    lac operon actually came up in the exam! this really helped :)

  • @raplords00
    @raplords00 8 років тому +2

    That was a damn fantastic informative video!

  • @d1g3rat19
    @d1g3rat19 15 років тому

    Absolutely masterful video!

  • @varunbhm
    @varunbhm 14 років тому

    Easy way to understand d process. Good work.

  • @MsY3n1
    @MsY3n1 11 років тому

    This is super genius.i watched it once and i don't need to open my book anymore..^.^

  • @Forlo12345
    @Forlo12345 14 років тому

    There is a CAP activation protein and it is VERY important (although, not necessary for expression of the regulatory genes).
    Here's how it works (if you or anyone else aren't sure how it works):
    if there are low levels of glucose, then the cell needs another energy source (like lactose). As [glc] is low, [cAMP] should be high, and this is the substrate for CAP to activate it. The active CAP binds to the promotor sequence and facilitates the binding of RNA polymerase.

  • @gulfamjameel1703
    @gulfamjameel1703 2 роки тому

    thank you for saving my time

  • @padmavathyk9282
    @padmavathyk9282 4 роки тому

    Thank you sis it is greatly used for me.keep on

  • @Mskhan-wp3rt
    @Mskhan-wp3rt 8 років тому +1

    thnk u soooo much for clear concept. :)

  • @jeffmcknight4818
    @jeffmcknight4818 11 років тому

    That animation is badass.

  • @khalifah95
    @khalifah95 4 роки тому

    simple and valuable. well done

  • @nareshchinta893
    @nareshchinta893 4 роки тому +1

    OMG that's cool I was just wondering this helped me a lot thank you so much for this verio

  • @madhupaul9088
    @madhupaul9088 4 роки тому

    It was really oossmm ..it helped a lot ✨..thank you so much for making these efforts😁

  • @azgari846
    @azgari846 3 роки тому +1

    Excellent explanation

  • @anvongocphuc8531
    @anvongocphuc8531 2 роки тому

    i love it. thank you so much :33

  • @digitalfaiza
    @digitalfaiza 6 років тому

    Thank you mam.it was very useful for me for understanding the lac operon

  • @mwklymkowsky
    @mwklymkowsky 12 років тому

    The entry of lactose into the cell is due to the noisy expression of the lac operon, which leads to low levels of permease even in the absence of lactose ; similarly the transformation of lactose to allolactone (the actual allosteric effector of the lac repressor as already noted), is mediated by b-galactosidase (which again is present at low levels due to noise in gene expression.

  • @onlydreaming
    @onlydreaming 14 років тому

    ndsu, all your videos are amazing. north dakota state, you know what's up! haha. thanks so much.
    as for lac operons, isn't there a CAP activator though? i'm not sure if that's important or not anymore if this video didn't mention it

  • @Sciencegurukul108
    @Sciencegurukul108 6 років тому

    Best animation on lac operon..👍

  • @Kha1i107
    @Kha1i107 15 років тому

    incredible video. Thanks you so much

  • @juliomiranda8296
    @juliomiranda8296 8 років тому

    MILLION THANKS!!!!!

  • @NormanBatesIsMyMum
    @NormanBatesIsMyMum 15 років тому

    That was a good video it defiantly saved me hours of deciphering my crappy notes.
    Btw the third protein is lactose transacetylase

  • @Bmenz18
    @Bmenz18 15 років тому

    This video is so simple and brilliant :)

  • @MrCpBong
    @MrCpBong 10 років тому

    Thanks! It was very helpful

  • @monomnn
    @monomnn 12 років тому

    Great animation. Thank you :D

  • @dhanamaninagaraj1299
    @dhanamaninagaraj1299 4 роки тому

    Just 3 min video and i am clear with the concept ..applause🙋

  • @lumarlucena2384
    @lumarlucena2384 8 років тому

    Very easy to understand! Thanks. :D

  • @cowboys430isback
    @cowboys430isback 11 років тому

    Awesome and very informative video. Thanks!

  • @lmavila77
    @lmavila77 14 років тому

    Beautiful!

  • @chumdejam7984
    @chumdejam7984 3 роки тому +1

    Pristine animation, easy to understand ty :)

  • @felso1234567890
    @felso1234567890 7 років тому +1

    so beautiful

  • @adityasengupta887
    @adityasengupta887 6 років тому

    Superb video!!!...Full concept clearing..

  • @Himabindu_Ar
    @Himabindu_Ar 8 років тому +5

    good picturisation...................

  • @esraazawi4231
    @esraazawi4231 8 років тому

    كلللللللش استفاديت الموضوع جدا صعب والفديو سهله شكرااااااااااا لكم

  • @xyzjoanna
    @xyzjoanna 12 років тому

    @jolymate This is a negatively controlled inducible operon. This is because the product of the regulator gene is required to shut OFF the expression of the structural genes (Z,Y,A).

  • @NIKSTAR2008
    @NIKSTAR2008 16 років тому

    another awesome vid, thx guys your viedos helped me a lot!

  • @ca567713
    @ca567713 10 років тому

    im flying though my notes bc of this video! thanks!

  • @ajhasan18
    @ajhasan18 12 років тому

    great explanation

  • @onlydreaming
    @onlydreaming 14 років тому

    thanks forlo! that cleared up some of my confusion :)

  • @liamfirth2513
    @liamfirth2513 2 роки тому

    Goddamn, these 3D art science visualisations crack me up!

  • @monicasinger8020
    @monicasinger8020 6 років тому

    Thank u so much. It's very useful for me

  • @Iinachanel1973k
    @Iinachanel1973k 3 роки тому +1

    Very helpful! Thank you! xoxo

  • @bra1nuts
    @bra1nuts 14 років тому

    Very helpful with my studying, Thanks!

  • @mansahasare9450
    @mansahasare9450 9 років тому

    Oh my god!! that was wonderful!!

  • @blessy091
    @blessy091 14 років тому

    Truly amazing:-)

  • @ArvindYadav-sq1ky
    @ArvindYadav-sq1ky 6 років тому

    It is much good ...thankuu so much 🙂it really helped me a lot

  • @TOXICASSLEAKAGE
    @TOXICASSLEAKAGE 12 років тому

    This is actually a little broad. When Lactose first enters the Prokaryote some of the lactose is converted to Allolactose. Allolactose is the inducer molecule that binds to the repressor molecule that removes it from the Lac Operation site and allows mRNA polymerase to come in and transcribe the operon

  • @anuprernapgangadhar3542
    @anuprernapgangadhar3542 3 роки тому

    Wow, really well explained

  • @niharikahazarika7425
    @niharikahazarika7425 3 роки тому

    Thanq sooo much , this is really good video