What The GTA VI Scandal Really Exposes, MrBeast, Amazing CRISPR Advances, Prison Labor & Todays News
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- Опубліковано 10 чер 2024
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✩ TODAY’S STORIES ✩
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00:00 - UK’s Ofcom Considers Facial Scan Recognition for Adult Content Sites
03:01 - GTA VI Trailer Smashes UA-cam’s Most Watched Record After Leak
05:46 - On His Deathbed, Man Reveals to his Daughter That He’s a Wanted Bank Robber
09:11 - Tuohy Family Accuses “The Blind Side” Michael Oher of Extortion
10:34 - Sponsored by Vessi
11:29 - Colorado’s Broken Prison Labor Promise
17:09 - Sponsored by Cozy Earth
18:15 - UK Greenlights World’s First Gene-Editing Treatment
23:39 - Your Thoughts on Yesterday’s Stories
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Produced by: Cory Ray
Edited by: James Girardier, Maxx Enright, Julie Goldberg, Christian Meeks
Art Department: William Crespo
Writing/Research: Philip DeFranco, Brian Espinoza, Lili Stenn, Maddie Crichton, Star Pralle, Chris Tolve
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#DeFranco #MrBeast #GTA6
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Politicians making laws against adult content tend to be the ones who end up in a scandal regarding it.
Man, that idea to use facial recognition for adult site is soooo dangerous. It'd be just a matter of time for someone or an organisation to proclaim something as a sin, or evil, or whatnot, and make a list. Just think about the religious groups that would love to know who likes butt stuff...
@@0eulogra0 That is quite literally part of the plan. Read up on Project 2025.
@@0eulogra0my guess would be a lot of those religious folk are into butt stuff......
Just like the p*dophelic Catholic clergy and politicians who won't shut the fk up about drag queens
Yeah, but also I think if parents are concerned, what their kid watching online *parents should be parents* and block adults site don't let the government have a Reason to shoot a microphone up my butt.
A non-violent bank robber confessing on his death bed and then his daughter profiting? The American dream is real!
Now all we need is to really know who DB Cooper is and all will be right in my universe 😂
@jfinney225 could be someone's cool uncle cousin or sibling dealing this.
@@jfinney225I thought Loki did it,lol
@@jfinney225I think he died in his fall, honestly speaking.
I would tell on his old ass too
As a game developer, I gotta say thanks for mentioning that people shouldn’t be harassing developers. It shouldn’t have to be said, but there’s no chance that guy that nuked his entire account wasn’t because he 100% needed to for his own well being.
I'm planning on going into the same field, and it's terrifying seeing how many people go that length to harass developers. It's like it's been normalized.
@@insulterman988 I wish you well on it and all the best. I think there has been improvements, slowly, but the main thing is to be wary about immediate channels to contact/find you. Never have a resume out there in the wild with your address or personal contact info. You include that stuff in your cover letters or application to a company.
Saying you can’t run your state without prison labor is saying you’re incentivized to lock people away. Its disgusting.
Honestly, Rockstar acted so fast I didn't realize that the trailer was leaked.
i saw the leak someone really put buy BTC lol
Same, I got the notification from Reddit first (which is funny bc I don’t play GTA and therefore don’t subscribe to any GTA subreddits lol).
Ya and it's all going to just kill the hype before the game even comes out.Not even released on PC and nobody knows if 2025 is to just shut people up or a real date. Don't buy the pre-order if they offer. That could be the first sign the game is shit and not even done. Nothing has told me this will be playable either. I hope it all delivers and in a timely fashion. History has made me a cynic tho...
@@ronswanson1410considering their investment cAlls has stated they were going to get a multi billion dollar influx at thAt time frame and that would seriously screw over Take 2, if that ends up happening. Fully believe it'll hit that fiscal target
When was the last time Rockstar delivered a bad game? Pre-orders are pretty standard for games since forever ago.
The facial scanning is a dystopian nightmare and when has any supposed "sensitive data" actually stayed private and not used nefariously
If u have a passport or driver's license or iPhone. The government has your face 😂😂😂
@@ccoonnor9953 one thing is the government, another is adult sites getting that information and then getting hacked because they probably have shitty security
@@ccoonnor9953I don’t think people are worried about the government having their faces. It’s that there will be data on people’s (what should be) private activities that will be up for grabs by various organizations and hackers. On top of that, what OP is saying about these companies saying the data they collect will stay safe and not be collect, sadly usually ends up being true; they don’t do what they say.
@@ccoonnor9953brain-dead take. Obviously the government has our faces.
Not at all the same thing as every adult site you visit having your face.
@@ccoonnor9953at least they don't know what corn you watch yet
As someone who doesn’t live in the UK but is a consumer of “Corn” (I always like using this sensor because it’s hilarious.)
3 things come to my mind.
1- Would a system like that even work at all?
2- What happens if you have an adult who has a baby face? or the opposite, where you have a kid who has an older looking face?
3- I do not trust them one bit by simply saying “will delete it promise. :)” No way.
At the end of the day, why do we adults need to be punished for someone not supervising their kids? If you can’t trust your kid in a park alone don’t leave them on the Internet alone.
its a biometric scanner that links with your passport or an id card. Same as biometric scanners at airports. Where they scan finger print, face, eye etc. It just compares it against the database to see if there is a match.
@@snake555510How the F are they gonna do that when I'm on my desktop PC without a webcam?
It's just porn. The UK is so weak.
Gotta love parents decision making. Uhm do I use parental locks on my children's devices so that little Jimmy and Susie dont go to adult websites, or do I allow big government get bigger and more evasive in everyone lives. Dystopia or parenting, tough decision I got to make while drinking box wine.
This is a hot take but let the little tikes have their porn. You did it, I did it. I draw the line at advertizing to children but if they are seeking porn they will find it. Its better to have a conversation about being safe online and what to look out for while granting them privacy than have them figure it out with out proper guidance amd possibly have a creep do it for you.
@dannyg.4421 I completely agree.
Also, even if data isn’t collected, that barely matters in the scope of this situation imo. This is still a disgusting breach of privacy and personal dignity.
I love how OFCOM's reasoning for why you should not worry about the facial recognition software is that "it would be a legal requirement to delete the facial recognition, after use". Yeh like every company everywhere has always followed the law and all it would take is 1 or 2 employees who need money for these photos to be saved and then used for "extra income".
You could use the same argument for anything and everything though.
"Yeah the car dealership requires my bank information to purchase this vehicle but all it takes is 1-2 people to steal/leak my information for extra income"
It's okay to have skepticism, just wanted to point out, that type of paranoia will just have you never trusting anything.
@@wiredoge6778 you're right but this is completely unnecessary. no need to risk a potential data leak for something so silly
I love when I hear the "They have no reason to do that" defense. Like dude, they have every reason
True, but in most cases if you have your bank details/passwords compromised you can easily change them to prevent anyone from accessing your account again to prevent further theft. Whereas with facial recognition I doubt many people would want to undergo facial reconstruction surgery to prevent themselves from being extorted again. @@wiredoge6778
A lot of these people don't realize that is a law and that laws are made by people looking to impress the public and increase their influence. It just takes a little spin to turn 'protect the children' into 'persecute the perverts'. Even if it isn't blackmail, it's putting the power to exploit your private life into the hands of the most vile scum on the planet - politicians.
My county is able to function without using the people in our jail as slave labor. The fact that they are admitting openly that they NEED people to be criminals so they can continue status quo means the status quo is really fucked up...like at a fundamental level.
I also think there is a huge difference between "We will have you work inside the prison for upkeep, like cooking or doing laundry, BUT will also provide you with job education/apprenticeships so you can find gainful employment after you leave" and "We will have you work in prisons for upkeep... but also have you cheaply produce items that we will sell for a profit".
Making people work isn't an issue in and of itself if it's to help them integrate into society once they're released, but making others do cheap labour so you can profit, THAT sucks.
@@Windmelodieit's also not like they have to have them stopped working, they just have to be paid. It's not forced labor if you pay them minimum wage to do a job that a minimum wage worker would be doing if they got rid of forced labor.
@yueviathan It is not as black and white as you claim, if these people were not incarcerated they would have to work at home to wash their clothes, feed themselves and maintain their living premises, why should they not be required to do the same in jail? Should they just be allowed to sit around on their ass on the taxpayer’s dime?
Similarly, most people have a job and earn a wage to support themselves in society. Anyone in jail should be required to do these same, they should work and be compensated for that work. The wage they receive can then be used to buy special items they are allowed to purchase from the commissary and to set them up with start up cash when they are released.
@@yueviathanyou gotta realize a large hunk of Americans are fine with slavery and death as long as they feel the population deserves it. Which is why they don’t give two fucks about anyone in prison
Those politicians are pocketing money off slave labor. If they make it illegal they'll lose income.
The gaming community can be incredibly volatile. I work for a company and over one small dispute I’ve had a player slandering me on public forums for months. It’s risky to have a player facing career in the industry. I’ve literally been fearing for my safety of being doxed for upholding Player Safety terms. While we appreciate passion for games, we’re real people, literally just trying to do our jobs at the direction of our company.
Having worked call center jobs for years, to be forced to do that as a prisoner is just evil.
Working in them barely feels like a choice when it IS a choice 😂
I can't imagine how hellishly bleak they'd feel if you literally couldn't leave.
for nearly free
Hey Phil, I am a Sickle Cell disease patient and this nearly has me in tears. Sickle cell is SO painful to deal with, physically and emotionally. The regular pain crises, low energy, shortness of breath, brain fog, reduced ability to work, missing major life events due to being hospitalized, having to relocate to warmer cities; and I have the *easier* variant of the disease to deal with. I was literally just last night learning about what CRISPR is, but I had no idea it was anywhere near clinically studied enough to be approved. I hope that research into treatment continues going in the right direction so fast!
I lost a sister due to a stroke triggered by sickle cell disease, and the rest of my siblings still struggle with the disease. While it'll likely be outside my financial range, the possibility of this treatment is mild boggling and leaves me hopeful. And it'll only improve from now on. I weirdly want to cry.
I also have sickle cell and was in the hospital yesterday, the way they treated me left me in more pain than when I went in. This new treatment sounds like a life saver!
Stay safe and I hope you recover as soon as possible 🙏 ❤
I'm in pain for a different reason so I understand your struggle. This gives me a lot of hope.
Trust king, it is.
My uncle was a firefighter in prision. He did everything they did and even more jobs that were deemed too dangerous for the "real" fire fighters. With out him and other incarcerated firefighters lives would have been lost and fires would have continued to spread. But when he got out they wouldnt let him get a job as a fire fighter because he was incarcerated. While he dosnt regret the lives he saved he could have been gaining education and job experience he could have actually used when he got out.
He should of got a job with that states bureau of land management. As a felon you can still work as a wildland fire fighter(the kinda firefighting we did in prison) but not a city fire fighter.
I agree. These laws gotta change.
thats a bummer having an ex-con as a dad... yeah man, there are rules to life and restrictions to those with felonies. its too bad it took your father getting caught to find his calling. oh well, he can always do what other men do...get a job doing construction.
@@30.06onaGrassyKnoll Stop judging people. You don't know what his dads life was like that he ended up in that position. Why'd you even comment at all?
@@30.06onaGrassyKnoll Listen, I know those who are hurt, hurt other people. At some point you just have to grow up to realise, that if you act like this towards others, your existence is worth less than this man's, who has done his time and saved lives in the process.
I mean sure, there's no requirement, however just imagine how much kinder your own kind would be to you, if you just acted with compassion and empathy, instead of vitriol and disdain.
Being in CA I heard about the forced fire fighter labor in my state many years ago and was disgusted by it. I remember everyone being upset by this news and thought we had done away with it. I guess I was young and naive cause I was today years old finding out we still do it. It makes me angry for being in a state that's supposed a "liberal bastion" that we are still allowing modern day slavery to continue.
Oh no, you're wrong. It's a liberal bastion, but only for the very well off. 😂
I'm waiting for them to pass laws banning non electric vehicles. That way us poor folks will get fined into homelessness and you know what we do to the unhoused here. 😞
You have been lied to about your Liberal Agenda. Wake up sheep. Even conservatives are being lied to. Nothing is black and white, question everything.
dont feel too bad, anything that is a "liberal bastion" is only that until you look under the hood and when it comes to money. rarely does anything actually change for progression when it makes rich people money.,
The 13th amendments prison loophole is why my mom and bunch of other people we knew lost their jobs as phone reps for AT&T back in the 2010s. People tend to assume it was international outsourcing that was happening so often at the time but no, they stayed in the county using the last remnant of constitutional slavery in the US.
Michael Oher was upset and heartbroken; of course his texts are going to use strong language. Claiming that his tone was akin to threatening extortion, however, just reveals more of their "Bless your heart" energy.
Theo Conrad knew what he was doing. He knew his daughter couldn't keep a secret if it killed her, and framed it that way so his daughter could use his posthumous infamy to live in luxury. Nicely done.
What a legend. It really was so damn easy to just dip out, go a few towns over, and never be seen again back then.
"Ed, do not eat that dirt"
Lol 😏😶🤤
To live in luxury? How? This only shows that the MAJORITY of females on this planet have zero integrity, no accountability, they're selfish, attention seekers, and they will always use any and every opportunity to throw a man under the bus. This is why the saying goes 'Don't trust no Biatch'.
I mean...that is a nice thought. But you could be TOTALLY wrong.
The law didn't find him until after his death, apparently someone sent in his obituary. Which made them to connect the dots, his daughter even got a visit.
As someone who was a teenage boy at one point and who works in the tech sphere now, I don't see any law being made that will solve the problem of kids getting access to adult content. My family had content blockers on the family PC when I was younger but all that did was push me to find the more dangerous sites and when I was finally caught looking at stuff, my dad finally had the talk with me about what I saw. You could even liken it back to when the older generation would find, steal, or be given dirty magazines. It's important that the parents have an honest talk with their kids about 1) the dangers of the internet and 2) adult content before they stumble into it.
On the VPN side, absolutely they hope for stuff like restrictive laws to happen because it creates a market for their product. No rational adult is going to plug a webcam in to get verified before they start watching anything on an adult site, that's a major privacy concern.
All restrictive laws like this are going to do is create a market for VPNs, punish those of us who are actually allowed to watch adult content, and push kids to more dangerous corners of the Internet.
@@H-to-O porn is bad, whether you like it or not.
@@SASMADBRUV7it's bad if not properly moderated, that's like saying sex is bad lmao
@@ItsPundore porn IS NOT sex. Not at all. How could you even equate the two?
Eh i've been watching it since i was 13-14. I turned out just fine. Teenagers will always seek it out in some way. Hell before we had a computer back then i would cut the lingerie section out of old shopping catalogs. Teenagers always find a way.
@methos4866 because as we know since it doesn't affect you, it doesn't affect anyone right?
I am almost 65 and I can't WAIT until GTA VI comes out. Having my kids at an older age I've felt that I've kept young through them. As they grew up I enjoyed watching them play video games. One of those games eventually became GTA of which I immediately fell in love with. I love it that my late son was always proud to say that he had a "cool" mom because I began to play it myself. I don't mind the wait especially if it means a better game.
This is so wholesome and sweet
When they make all these “safe guards” I’m always confused how these issues with kids falls on all adults. It’s really not my problem your kid has access to adult sites. Why am I being punished?
EXACTLY!! How about parents start parenting their own kids?!
@@mariomario1462 Exactly lol, kids will find a way regardless, be it Piracy, VPNs or something else. This is just an annoying step.
No one pointing out that you don't need a website either, just Google images 😂
That’s because it’s not about the kids. It’s never been about the kids. It’s always been about control, pushing their theocratic agenda onto everyone else, gaining and keeping power.
Yup. It's pointless virtue-signaling. It doesn't protect the kids, just punishes adults for seeking out their pleasures in a responsible format. The problems they wanna solve can't be fixed with a little piece of paper. It's gonna take years- maybe even decades -to reach the social consensus needed to root out truly harmful content (meaning not all of the erotic content, just the stuff that promotes criminal or potentially deadly acts), so until then, parents will just have to be parents.
Past Gameplay Animator here! Agreed on the sentiment of just showing kindness and patience while you’re waiting for a game to be released. Teams put so much time, effort, and care into what they make. We would prefer a game taking longer to make if it means we’re not crunching to make it. So showing support for the production team is also showing support (sometimes) for better work environments!
Now that I run a studio I’m focused on fair production schedules, which can be hard sometimes because there’s an expectation now for content to be delivered faster and better. So seeing companies delay games actually makes me quite happy, assuming their management is doing it for the right reasons.
the developer's son is a real pos who probably got him fired...
great reason to raise our kids to be an actual decent man and not a lil pos spoiled brat who only cares about himself and his social media.
I worked at Ubisoft for years, and honestly, when a game leaks it's heart breaking. We put all our time and energy into something and we gather together to watch the official launch and watch the numbers together and celebrate, and that community event is stolen from us every time a leak happens. For us, it's not getting to play the game we made that drives us, by the time it releases, we've played it dozens and dozens of times already, we live for that public release and the excitement of the public, it drives us. We live for the public response and excitement for our work.
I am so glad CRISPR is making strides. When I was thinking about getting a career in genetics, there was a huge pushback on both CRISPR and stem cell treatments. I’m glad it’s going strong today.
I have a friend that actually worked on the CRISPR research that won the Nobel prize a few years back. I remember her talking about "dude, we can literally edit DNA" and thinking how insanely sci-fi and impossible that sounded in 2020. Skip forward today, we're seeing actual applications. Science and teamwork never cease to amaze me lmao
Had a colleg prof who worked on the human genome project, he and I talked about this stuff all the time. Maybe I should try to dig up his old email to talk about this.
I'm a scientist and researcher who uses CRISPR. It's sequencing Salmonella genomes via CRISPR.
The technology used in the human genome project sequencing is such a far cry from improved CRSIPR/Prime editing we have now. The labour requirement is light and day. Also the human genome project focused on sequencing on DNA ie painstakingly reading each nucleotide, while CRISPR is more on editing ie, snipping one or few nucleotide and hopefully replace it with a desired sequence
Didn’t she lose the right to use it commercially?
@@llllllllllllllllllllllllIIIIl1 I know the difference, my point is I knew someone with decades of knowledge and a passion for the topic.
My dad has been incarcerated for over 25 years. He's always been required to have a job, but he's considered himself lucky because he had skills that helped him get a "better" job. He's a trained EMT and firefighter. He's trained manhunt dogs and participated in manhunts on horseback across wild areas, searching for dangerous people like armed robbers but also helping authorities find people like elderly dementia patients who have disappeared. He's save countless lives, been deputized so he can go across state lines during a hunt, and has built positive relationships with local law enforcement.
But when he gets out, he'll have a felony on his record and he won't be able to do ANY of those jobs. Also he's destroyed his body over the years with all this crazy stuff. And he's been paid nothing.
This CRISPR news makes me so so excited! As someone with a genetic condition who always thought we were hundreds of years off from being able to edit the genes of someone like me and remove my disability. That has always been a faniful dream you have no idea how much this news means to some of us in the disabled community
@@OpenWebChatno lmao
The prison labor story reminded me, this may be happening at homeless shelters as well.
At least the only one available I went to that toted how "We don't accept government funding so we can make our own rules" religious kind of shelters.
When I was homeless the shelter coordinator told me if I didn't participate in a work activity of 20 hrs a week or attend their continued education courses then I wouldn't be eligible to stay there anymore.
I was trying to maintain a fulltime job to get back on my feet and often came back after their night time hours with varied degrees of chuff from staff (despite clearance from admin)
This was after I had taken their mandatory 'intro' class that lasts 4 weeks, "graduated", and the 'continued education' was literally 90% christian bible study.
Not to mention their entire transphobic staff, forced participation of christian events, high barriers for entry..no wonder people still prefer risking a federal charge for 'camping' outside.
Fun Fact: The continued education was named after my Hometown college... 4,000 miles away :/
I shouldn't be surprised, but it is absolutely insane to learn that there are homeless shelters actively giving their tenants grief for trying to maintain employment?? What in the backwards logic is that??? How on earth do they justify it?
When I first heard of Crispr I was very excited because it meant people like my wife who suffer from a debilitating neuro-muscular disorder could possibly be treated soon enough before they lose the majority of their motor skills and become stuck in a wheelchair or bedridden. Unfortunately my wife was too far along with her disorder for it to do any good but it did give her some relief knowing it might be able to help people in the future. My wife passed away 5 years ago and I know I wouldn’t want anyone to go through what she did.
Sorry to hear that my friend be well and be strong
You already know this is going to be poorly regulated and turn in to high-end fashion…
Also, im graduating in criminal justice in a week. I'd just like to point out, the prison industry is up there with Walmart and Amazon in profits. It estimates about $74 billion a year in profits and only gains more the more people are put behind bars. In comparison, as Phil said, prisoners make less than $1 an hour.
And those billions will be passed on to the taxpayer if this goes through. Hell they'll probably find a way to make more money by using it as an excuse.
And those profits from underpaid or completely free labor are an incentive to make more innocuous things crimes. I wager it's one of the main reasons hard drugs are still illegal in America.
@hauntedshadowslegacy2826 and they still use those illegal drugs as form of justified ruling on it.
It's crazy that this isn't just being broadly called exactly what it is: minority slavory. The US has some of the highest incarceration rates in the world, where a majority of prisoners are disproportionately of minority groups. To top it off, there are people arguing to keep this for financial reasons, and punishing those who do not want to be slaves. The only thing that's changed since slavery was "abolished" is how these same groups of people are enslaved
I’ve been saying this my whole life, my father grew up next to a prison plantation during segregation, it is slavery, prison labor is the loop hole to keep slavery. There’s another thing close to my heart that’s linked to this, prisoners voting rights, allowing the government to force people to work and take away their voice obviously leads to bad incentives and oppression at the hands of the government and is responsible for mass incarceration. We do not live in a free country, America is a lie like the Soviet Union, the government is hypocritical to its core, and just like Martin Luther King warned we are heading to our own destruction as a result.
I could say a lot more about this but I’m very sick today
It's pretty easy to not go to prison.
@@Zenkai76I dunno about that, with stuff like the 3 strikes law, it's a whoooole lot easier than it is in other countries
@@TheGeoMash pretty easy to not commit 3 major crimes
@@Zenkai76 Don't even parking tickets and misdemeanors count as a strike?
The CRISPR story honestly get me excited. I have familialhypercholesterolimia and other than myself not being expected to live to older than 16 I actually lost my sister with the same condition when she was 16. I have only made it to the age I am because I have been a guinea pig for new drugs and treatments from the age of 3. I have been on statins as long as they've existed and in my case they really were/are not enough. I have gone through injections, pills, I.V.s and each time it seems to work a bit more. I probably won't live to be old but there are constantly new and young children joining the studies I'm part of. It gives me hope that new advancements in medicine will actually grant them a long and normal life.
I would point out that the UK doesn't have any form of government-issued ID and not everyone has a passport or driving licence. This proposal by Ofcom is disgusting and yet another indication of why they need to be completely reformed.
Or.....just get rid of porn
@@ronaldbeamon5564 While we're at it, let's get rid of alcohol too. They're in the same place, where it does no harm when _responsible_ adults are in all parts of it.
@@ronaldbeamon5564 that’s absurd! 😂
@@ronaldbeamon5564how? It's been around for thousands of years. Porn is not some new aged thing. Honestly if the human body wasn't considered some taboo thing that society deemed to be wrong to observe this wouldn't be an issue. Name one human being that's never had an involuntary chemical reaction to seeing something attracted to? It's human nature, and history shows that trying to stop human nature in it's tracks has never once worked.
@@jamesplowman9221 Some of the earliest drawings involved sexual depictions.
Crispr is incredibly exciting and utterly terrifying at the same time. Without free and equal access, it can lead to some truly dystopian futures.
From what I know about Crispr can do a lot of stuff and yeah it can be very bad in the wrong hands.
When CRISPR first came out in the late 80s/early 90s, there was a whole lot of hoo hah in the media about it being used to force out races. Almost 40 years later and nope.
Although yes, it COULD lead to dystopian outcomes, at this point and time I doubt it.
Also..... whether you have free and equal access or not, bad people always find a way.
It can never be equal because the individual will never be able to leverage it in the same way government can.
Consider the difference between google maps and doing a flyover in a helicopter.
Equal and free access but incredibly unequal
Keep in mind, with great technology comes great stupidity. CRISPR will remain mostly in check because we as humans will hold back the concept.
I've danced this piece enough times to be 100% it will lead to an even more dystopian future. Even the exciting parts only lasts so much because line has to go up and it has to go up faster and faster.
We've been using CRISPR pretty often in biology research. Its insane how powerful a tool it is and how much it has enabled research, and its become pretty common, almost routine in labs over the last decade. Having it enter the public sphere via medical treatment will be very interesting.
Hey Phil! As a masters student studying genetics, your portion on CRISPR was great! Well informed and had nice visuals! Awesome job. I’m also excited to see what else we can do with CRISPR.
As someone from Colorado, I'm glad you talked about what's happening. We need to keep our government accountable. People voted for this, now it's on them to accommodate.
I can’t believe NY uses them for DMV call centers. No wonder why they’re useless.
A huge issue with inmate labor (other than, obviously, the involuntarily part, and the below minimum wage) is that those inmates often times can't get those same jobs when they finally get out because they don't pass a background check. Prisons sometimes tout jobs inside as a 'perk' because they get job experience even though they can't actually use those skills when they get out.
This is a major thing I didn’t consider. Great point! What use is it to the prisoners if they can’t get a similar job after their release. Really defeats the argument that prisons are for “rehabilitation”
Below min wage? Hmm let's see, no bills, free food, free showers. Sounds like they're getting paid to me.
Fuck em, they owe me a debt, I'm a part of society, my taxes put a roof over their head and food in their belly and a Dr to take care of them.
Ya they can work bc I have to work to pay for all of that.
It's a PUNISHMENT.
The perk is good time and extra privileges. Also having something to do other than sitting around. Good time is a huge deal and was severely underplayed in this video. IL matches their days. So you work 30 days, you can get out 30 days early. Depending on the crime, you could serve 50% for flipping some burgers or mopping some floors.
@@joeyjdevivo11you sound like a bitter old man ranting in the home. Nastiness is a disease
@@cathmorr89 Which also creates a financial insensitive to sentence prisoners to jail time in those states. We have plenty of historic data showing that government bodies will push for actions when the outcome affects their budget.
Coming from a family with Huntington’s Disease, (My mom is in the late stages, and I have a 50/50 chance that I also carry the gene) the crispr segment brought me to tears. I’ve been following crispr news for years, hoping that some good news will come. It may be too late for my mom, but I’m hoping that if I have the disease, this will be a viable option sometime in the future. ❤
Cautiously optimistic is definitely how I'd describe my feelings about the CRISPR story. I have Ehlers-Danlos Syndrome so this whole thing could actually be something that would help/cure my disease.
I don't know the logistics but I hope it comes to a point eventually where it may be a treatment or solution entirely to my disability and others out there like me, too. It's exciting but also terrifying to me 😅
I am a Cancer Biologist with a Ph.D. in cell biology and molecular genetics. Thank you Phil for covering the CRISPR story. You did an excellent job explaining the science behind it. The major problem for CRISPR in my opinion, is the penetrence or how much the other cells take up the sgRNA and CAS9 plasmid. The bone marrow is an excellent starting point and I am happy that they are seeing these good results.
I'm a ncRNA person myself and I get twitchy thinking about the indel rates and some of the optimization that needs to continue but still feeling generally excited about the prospects
Okay, will take you at face value you are what you are. I have a genuine question. Evolution has always been about the “faulty” genes being eliminated by natural selection. Which is generally seen as a good thing. Are scientists and doctors worried that by advances in medicine, that there is a risk to the overall quality of the human gene pool? I’m not saying by any measure that these people should just die, god no,mad a parent myself I would do anything for my son. But I am thinking bigger picture. Is there any evidence to new conditions emerging related to this, more severe afflictions, or, more frequency of certain conditions that otherwise, without modern medicine would have seen the person afflicted die, or as seen in history, unable to find someone willing to procreate with them due to this affliction?
I'm a research scientist working with CRISPR and agree. Any situation where you can select cells that go back into the patient like bone marrow is promising, but I would be concerned about penetrance/off target effects for entire organs somehow being edited. I agree that whole genome sequencing is essential to see what the expected off target effect rate and guarantee that the cost of a genome isn't even that high nowadays. My lab does genetic sequencing for a rare disorder and clinical genomes are only a couple hundred dollars nowadays. (Expensive for the average person, but not for most academic labs)
@@macapaxxagreed, I think safety is in the eye of the beholder. Some folks are willing to risk it, whereas I've seen far too much off targeting in just in vitro experiments. And then to go even further, if this gets introduced to germline cells (it's going to happen) I have serious concerns
I didn't even make it through college but reading this thread makes me happy people like you guys exist. Cheers!
I always said instead of getting rid of prisoner forced labor just pay them the minimum wage. Placeing it all in an account for them as starter money when they get out. So they don’t fall back into the situations that may have forced them into crime.
Those forced labor laws also incentivize over policing and higher sentencing for minor crimes
The older closing line felt like a warm blanket 😊
Th simple "& I'll see you tomorrow" is so nice
"But it's a legal requirement ..."
Corporations ignore laws all the time. Paying fines is just part of their business model.
"all the time" Can you quantify that?
It blows my mind when self described ‘mega fans’ go after developers of the games/content they love. You love it SOOOO much that you will abuse and threaten the people making the content just because it was slightly delayed (in order to make it a better, more complete product), but will also threaten them if they cave and release a subpar product earlier to try and keep you happy. At the end of the day, devs want the game to be the very best, it’s generally the execs who determine release timing based on hopeful revenue.
These "fans" are also more than likely the same people who suggest using AI to get the product out faster.
They don't care about the humans behind the games. They will proudly defend harsh working conditions if it means that their favorite corporate logo keeps making their favorite digital timesink.
I was a jail Sgt for 15 years. Jail, not prison, in California and forcing inmates to work is one of the things that haunts me the most since leaving. Forcing every able-bodied person to work or risk not getting visits, phone calls, or canteen is cruel.
And you did this for 15 years and never fought for their rights?
US Transplant coordinator who works closely with a doctor doing CRISPR trials in America for a certain type of adult leukemia/lymphoma and I cannot begin to explain how nuanced CRISPR is. You should also look into CAR-T cell therapy we’ve been doing for several years now and look into the price tag on that.
As a person who has Sickle Cell Anemia, the CRISPER developments are amazing! To be completely or almost completely rid of this horrid disease will be the best thing that would ever happen to me. I really hope the US will approve treatment here.
I hope you can get treatment very soon❤
Coloradoan here. If the prison system would crumble without slavery, then maybe it's time to stop imprisoning so many people for non violent crimes.
So you think a majority of people should not be imprisoned for non-violent crimes? Take a second to actually think of the implications before you respond lmao.
@@sarteronthat actually sounds okay. What with prison generally leading to recidivism, and understanding that crime is generally a reaction to income inequality, there are far better ways to aid and teach those who commit non violent crimes. Some sort of education and community based service and direct compensation to those affected may help those involved develop a sense of community and help improve the lives for those who feel criminal acts are their only outlet. It’s just one extra tool that can be used, in tandem with incarceration. Regardless, people in America are over criminalized, and a grand majority are in prison for drug related offenses, which really shouldn’t be a reason to be in jail to begin with. The person you’re responding to is likely thinking, and if you want a window into their thought process, take a look into articles and essays on prison reform, and I think you’ll understand their view point more succinctly!
@@sarteron The alternative is house arrest. Ankle monitor, parole officer monitorization, restricting access to the internet. Maybe some community service. Or just fines depending on the issue. There is no reason the prison has to be a facilitated one rather than one at home.
It's not like going to prison teaches you to be a better person anyways. It doesn't fix the problem. It only hides it away. And if fear of prison would have stopped them in the first place, then it wouldn't have happened so as it was. . . so the "threat" of prison doesn't exactly work either. :/
Granted, such a change might cause the crime-rate to go up however. But that's why we should be looking into different methods of instilling fear into the average citizen in ways that don't require governmental overreach like making non-violent people become subjugated by corrupt and exploitative people in positions of authority.
@@sarteronYeah, actually. People get sent to prison for parking tickets bro
Agreed. Better to enforce no laws than to enforce them without real justice. Criminal activity is a factor of human behavior. Trade out the prisons for the mental health system Reagan thought was after him.
As a gamer, I’m just happy we’re getting confirmation about GTA6 coming out. I don’t mind waiting till 2025 for game. If Rockstar studio’s need more time to tweek and smooth out gameplay. LET THEM COOK! Late is for a little while, Suck is forever!
I remember just last year in my biochemistry course the lecturer talked about CRISPR treatment for sickle cell disease as a somewhat distant idea and not something that would be coming in the next few years. It's amazing to me how fast this treatment has been able to advance, though of course caution is still incredibly important like was mentioned, it brings me joy that more and more people will be able to get relief from these awful diseases through CRISPR treatment
Ofcom story is horrifying from a privacy perspective. I think the whole conversation around how to stop kids from viewing pornography needs to happen with parents having frank discussions and talks with their kids early on on sex and the human body, the fact that most western countries are so averse to anything regarding sexuality is harming people so much.
Keep in mind even if they did kids could just buy pass it so many ways and some kids just look old
@@mp32298Yeah, a not insignificant number of middle and high school kids have gotten in trouble for hacking their schools' computers and changing grades. Looking up erotic materials online despite anti-erotica laws? Puh-lease! A walk in the park in comparison.
That's the biggest issue imo. Parents are so afraid of discussing sex with their kids that they have to look elsewhere, and that elsewhere almost always ends up being porn. And porn is the last place you want your kids learning about sex.
When I was a teenager there were laws to prevent us from getting our hands on Playboy or hustler magazines but it didn't stop us, we found a way lol... These laws aren't going to stop anything and seriously will only put people at risk. They can talk about laws to protect people's private data all they want but those same laws existed and applied to almost every data breach that's ever happened.
The dirty magazines are probably safer than most of those websites.
@@nightigalno doubt lol
Out of curiosity, do you you share this opinion on matters of drug legalization?
@@Rodrik18are you asking if I think people should be subject to facial recognition scans to legalize drugs?
@@Rodrik18 What?
I remember hearing the problem with CRISPR is that all genes are related to other genes, sometimes genes that are unexpected, so changing one can have very strange side effects. but it’s still an amazing technology
I heard about Crispr on a Netflix docuseries called “the future of”! They were talking about the future of plants and how people use Crispr to edit the dna of plants!!! Cool!
Michael Oher learning he’s not adopted is devastating. Just lying on that fact should be enough to force some sort of judgement. Going around saying “we adopted him” but never having done so is fraud. He absolutely deserves to be paid from that fact alone. It’s the only reason anyone saw what they did for him as meaningful. Absolutely disgusting.
It is absolutely mind bending what these people did. You have to be delusional to call that treating him with love, if they ever genuinely cared they would have adopted him. Then the audacity of pretending that they did, profiting off of that lie...just takes it to a whole different level of absolutely fucked.
Thanks for covering CRISPR advancements. It's incredible technology that will change lives. My sister passed from Sickle Cell Disease a few years ago and I'll never be the same. If CRISPR/CAS 9 will eventually cure SCD, that will bring me to peace. Thanks Phil.
I am so sorry for your loss. I pray that something forces the hands of those that will be handling the legislation/access/pricing surounding the tech since it is known that those in charge tend to not care about health as much as profit. They have no incentive to cure anything which is pure evil...
I hope something changes
Sorry for your loss. 😢 I truly hope this will turn out to be a meaningful step towards a cure.
Hope you're doing okay; that can't've been easy. Here's hoping CRISPR won't be permanently locked behind a prohibitive paywall so insurmountable that its benefits never reach the people who need it most.
I ACTUALLY REMEMBER Thomas Randell’s/Theodore Conrad’s bank heist episode of Unsolved Mysteries
Damn
Good job with the pronunciations :) I just took Clinical Hematology 1, and my goodness, the amount of times I had to stare at words to figure out the pronunciations was hilarious.
The forces labor thing is so insane. If we paid prisoners even minimum wage they would have a better chance of living a normal life once they leave the prison. The reason so many prisoners reoffend is economic ones. The US pays them pennies, then when they get out they struggle to find a job because they were incarerated.
Yeah, I love hearing all the prison industrial complex types talk about how prisons will be too expensive and collapse without forced labor. It's almost like maybe we shouldn't be imprisoning so many people... Weird. 😒
Maybe they shouldnt commit crimes in the first place... Plus they are already getting free room, food, clothing, utilities, medical, etc while incarcerated.... They would be better off than most ppl in general if they got minimum wage and didn't have to pay any bills for as long as they are in prison..... That's ridiculous... Where is the actual punishment? It's starting to sound more like working at a resort or on a cruise ship.
They should have to do something productive to pay back what is being paid for. I don't see the issue in low or no wage work bc they are being paid in non monetary goods already that they would have to absolutely have to pay for otherwise
I DO think they need workers protections though.
@@TheTemptress13100% I was thinking the same thing. So tax payers pay for the inmates “housing” which allegedly cost us $70-100k per year (depending on the institution) and we pay them a minimum wage? I don’t think that will fly with many people
@@TheTemptress13 . totally. not like there are any innocent people in prison. I mean 2022 only had like 250 exonerations.
@@Greant76 if they are exonerated then they won't have an issue finding employment when they are released bc they won't have a crime on their record. Also, should all of the guilty people not be punished bc of the possibility of a few who are not? I'm not saying the system is perfect... I'm saying get a good enough lawyer to sue the state for lost wages if your exonerated. Lol
Trying to force face scans for porn sites will just force users to using Tor and VPNs.
I’m willing to bet vpn companies are lobbying for these laws actually.
Best way to sell a solution is to create the problem yourself.
POV: You're going to Brazil (digitally)
5:32 I don't look at the news much so I was confused when there wasn't any new episodes but I just thought "hmm that's weird" and went on with my day
6:38 What a twist
"GUYS! WE CAN'T STOP USING SLAVE LABOR. IT'S TOO CONVENIENT FOR US!" -US prison system
As someone who was diagnosed with Leukemia at the age of 6 going into remission at the age 9 and thankfully not having had a flare up since the CRISPER success story made me tear up as I was driving home. I've been following this for years because it sounded like something that could help stop kids going through what I had to go through. All these cancers and diseases created by errors in our DNA through no fault of our own most of the time is a special type of hell I wouldn't wish on any one. No kid at the age of 6 should be thinking of the limits of their own mortality and no parent should fear loosing their child to an illness thats slowly destroying their body. I hope research in this continues and gets better as quickly has AI has advanced over the past year.
I'm sorry you experienced that 😔 no child should have to hear the word cancer in their direction. I had sereomucinous type ovarian cancer Stage 1A, papillary thyroid carcinoma, and precancerous adenomas so far. I have a mutation in my chek2 gene which is a tumor suppressant gene so I'm at a higher risk than the average person. But I also have hypermobile ehlers-danlos syndrome which comes with autoimmune disorders. So I've been following this for years also for the same reasons as you. Hoping that we can end cancer as much as humanly possible especially for children. It's sounding promising still. Very technical and difficult but promising.
🫂
For the prison labor section, I recommend the book, “The New Jim Crow” by Michelle Alexander.
"Feed two birds with one scone." Less violent way to say the phrase. 😅
We should be trying to teach teens sex ed and understand the sexual spectrum instead of having adult sites invade people's privacy in some weird gambit to get them off those sites
My late husband was diagnosed with a very aggressive myelodisplatic syndrome (a type of bone marrow cancer) in june 2019. At the time, CRISPR was still in experimental stages, he would have been the ideal candidate for a study. Sadly all the experimental treatments in my area we not accepting new candidates and we could only barely manage his illness with transfusions and chemo. He passed in November of the same year.
Since his disease genetic analysis pointed towards a family genetic disorder, this gives me hope for his younger siblings and family that might develop similar syndromes later in life.
I am amazed by the results and I would have wished for him to have be a part of these experimental groups.
The first GTA was created in my hometown of Dundee, Scotland! 🏴Lemmings game was also created here. Dundee gets a bad rep for being a pretty grim place to live, but it’s the home of some cool things! We also made Dennis the Menace!
That Cozy Earth sponsor spot seemed cool and then I clicked on the HOLY HELL they are EXPENSIVE!!!!!!!
Like my lord!!!!!!!
The OFCOM plan is insane, it should be the parents responsibility to watch what their child is viewing online. There are even laws in place already which mean all ISP have parental tool in place.
Michael Oher demanding compensation after being lied to for years is NOT the same thing as extortion.
It has the same energy as Elon crying about blackmail when advertisers dipped out.
They’re both wrong, as extortion and blackmail requires a literal criminal element by definition. More rich assholes muddying the meaning of real and serious crimes to play victim after being shitty people.
kind of sucks he only cares about money. more to life then that. itt was never in contract thatt said they owed him money. nobodies ever happy with what they already have, why want more, it's kind of unrealistic.
@@thedeadguy It's not just money. They PROFITIED off his own story, his own life, and he received almost nothing.
@@BrkfastMachine You do realize you do not really get that much if your story is made into a movie, right?
@@standepainthe family split profits of selling HIS story 5 ways, and he got 1/5. How's that fair? They were supposed to do yearly accounting of the conservatorship and never did.
I remember The Casual Crimminalist episode about the Bank Robber. That's so crazy
I like how the GTA 6 trailer broke record of the most views on UA-cam in 23 hours and great video man :]
It's awesome that you talk about companies being required to collect personal data that could be used to steal identities and then data leaks about GTA back to back. If we create data stores, they will be breached eventually.
Yeah just because a company keeps data under lock and key does not mean that it's a good lock. The only way to be truly safe is to NOT collect the data in the first place.
Genetics grad student here - CRISPR has been a thing for a while, I’ve actually done it myself to put glow genes from jellyfish into bacteria to make them glow. It’s one thing to alter one cell’s DNA but altering the DNA of a whole organism is completely another task (assuming it’s not a single cell organism). There’s so much good that can come from this tech but we HAVE to be cautious about when and how we implement it. People LOVE to argue about ethics in my field.
I did my undergrad research in CRISPR it's cool too see it talked about here so that others can learn about it
Ted Conrad was my great-uncle. Of course I did not know him. I thought he was dead. This segment is the most I’ve heard about him. Thankful that he had such a great, long life.
As someone who has recently had a voiceover career actually start to take off a little, I am so much more sympathetic to production and talent staff for running series. When you have both the demands of getting it right and getting it done in time competing with each other, the stress of it can be enormous. Almost worse than the stress that comes between jobs.
I'm currently in grad school for Biotech. CRISPR-Cas9 is everywhere. It is extremely common and considered a standard tool in research. There may not be that much public therapeutic use of it yet, but it won't be long before it will be more common. Our pathway from research to trials to widespread use of any sort of therapy is a long process, and we're just now hitting the point where research utilizing CRISPR-Cas9 is going into trials. However, in a few years, medicine will likely be revolutionized by both CRISPR-Cas9 and the multitude of other similar therapies that are being developed.
When the video opened up with "The goverment wants to scan your face when you open adult sites" I was like, "Whuuuuat!???"
That story about the girl learning the truth about her father is so incredibly awesome. That dude rocks lmao. Risked his life on a gamble and it paid off. Also, if my kid can live off my story and I wouldn't have to deal with it? I'd take that, fair trade to me.
On the last story as a researcher who has used CRISPR in the lab the risk of "off target" edits is really high. We really need to have the full genome of the individual. I think the biggest barrier to making this sort of therapy useful is the price to do whole genome sequencing (WGS). Ideally you would do it twice once before to make sure your guide sequences don't have any other near hits, then after to make sure only what you intended to edit was changed. Right now that is ~6,000 USD + the time and expertise to actually do the assembly. That price needs to go down, and it is, 20 years ago it would have been ~7,000,000,000 USD
By the time this gets approval let's hope the price keeps ropping like it has the last 20 years then.
This is why I'm not as excited about CRISPR as others. Editing DNA is awesome, but CRISPR just goes off and does it's own thing editing the wrong sections. The modified side effects might not be noticeable until years later. It's best to err on the side of caution when changing DNA, especially since we still don't know what most of our DNA does.
Illumina stock and other sequencing tech stocks are going to go through the roof, but I hope the demand makes a better and more sustainable pipeline for patients
😂LMAO the Thumbnail for the “Adult facial recognition” segment is of Michael Oher & the Tuohys lol
I love the content PhillyD.
Just an FYI on Vessi though. I had purchased two pairs of Vessi's and they both lost their waterproofing within a month or two of wearing. Daily walks with my dog in my yard (1-2 miles a day) on rough terrain caused leaks at the seem. I didn't want to bother with RMI at first and just accepted this was a bad purchase.
Eventually I did try to get a refund or replacement. I was too late on the one year warranty for one and near the deadline for the other. I finally decided to at least try getting back something for the wasted purchase, but they instead emailed me back that I needed to prove and show them where the leak was with some silly paper towel experiment. I gave up on them and just ate the $200+ in wasted money for two pairs of shoes that are very much not waterproof. Something that I really need in the PNW. Both in the same spots funnily enough. Not recommended for anyone that walks on ground that isn't completely level.
Regarding the other sponsor, $108.49 for their cheapest queen sized sheet is (Wow, how in the world would this not be considered a luxury priced item/priced outside most budgets) ridiculous, and I almost impulsively and blindly bought it as I trust you that much. Thank God I was paying attention.
There's a big push right now for people to turn back to physical media in light of streaming service removing content. I think there going to be a similar, much small movement back towards magazines and DVD in adult media if facial recognition for adult websites becomes a thing.
There's a reason I have a BluRay drive in my computer. Got hard copies of old games and movies that ppl can pry from my cold, dead hands. Not truly owning anything isn't okay.
Forever to be haunted not knowing whether Phil was joking about sexy clowns..
Just so there is no confusion if someone decides to search for it, BT is most commonly used to refer to Bacillus thuringiensis, a bacteria that is the most commonly used form of biological control in agriculture. It is also typically in reference to genetic modification, but with crops, and sometimes CRISPR is also used to make new crop varieties using Bacillus thuringiensis. Both use CRISPR and both are being called BT, but they are different things.
How can I close the app and still watch your videos!!! I can’t with any other channel! So dope!
The only good thing that could come out of the facial recognition p0rn site story is that we’ll start learning how to beat general facial recognition a lot faster.
This a form of grooming i appove. Train the youth to avoid surveillance(either govnement or corporate)
We'll also start hearing about the evils of file sharing, and a certain immortal torrent site will be back on the agenda when the porn industry starts pouring dark money into the wallets of politicians.
As a research scientist, THANK YOU!! Although, I feel like these amazing treatments only get covered at the ‘news release’ point. These same patients will be followed for the rest of their lives for data. Clinical trials don’t just stop when drugs are approved and at the rate of technology, I’m not sure how regulatory bureaucracy will keep pace. It is a very exciting and important field of study!
10:15 the blind side 2! Blindsided
As a biologist with a focus on genetics, this was a great description of CRISPR! Thank you for talking about this
There is never a case where being concerned about sharing personal data is "overblown." It doesn't matter if it's a law, procedure, or what ever false-hope idea of regulation you can think of, privacy is only protected if private information is never sent through anything.
The fact GTA 6 trailer got 90m views in a day is proof its the most anticipated trailer of all time
I stopped caring about gta since 4 (no hate on anyone that likes them, just got tired of sandbox games like that), but even I was hyped for this because GTA content is always fire on highlight reel
@yangofice8361 the story modes are quite fun
yeah but its also proof that the gaming community has no backbone. Constant complaining about microtransaction and soulless franchises but one trailer is all it takes to come running back to GTA. A game that only makes money of selling shark cards. A trailer for a game that wont come out for a year btw.
@@yangofice8361Same. Though I’m more excited for the inevitable, and hilarious, GTA6 Roleplay trolling videos from guys like Soup and Yumi.
the CRISPR story is so exciting!!! as a current student in neuroscience, i hope to work on things like this in a lab some day!! i've read about this tech in school this year :))))
The last time I heard of the CRISPR-Cas9 was from the news story a few years back regarding the human experimentation on two twins in China, and the various ethical concerns involved there regarding its use. Now in 2023-2024, seeing some movement and better optimization of the technology has allowed some treatment for genetic diseases. Hopefully there isn't too many issues involved though with any potential side-effects with the use of CRISPR-Cas9.