Why sex really matters | David Page | TEDxBeaconStreet

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  • Опубліковано 10 січ 2013
  • David Page, Director of the Whitehead Institute and professor of biology at MIT, has shaped modern genomics and mapped the Y chromosome. And he's here to say, "Human genome, we have a problem." Page contends that medical research is overlooking a fundamental fact with the assumption that male and female cells are equal and interchangeable in the lab, most notably because conventional wisdom holds that the X and Y chromosomes are relevant only within the reproductive tract. But if the sexes are equal, why are women more likely than men to develop certain diseases, and vice versa? This compelling talk from TEDxBeaconStreet foretells how changing the way we understand the sexes could transform health care.
    The Director of Whitehead Institute and MacArthur genius grant winner David Page is a pioneer in genetics, and his renowned studies of the sex chromosomes have shaped modern understandings of reproductive health, fertility and sex disorders.
    In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)
  • Наука та технологія

КОМЕНТАРІ • 884

  • @vanessaloy1049
    @vanessaloy1049 2 роки тому +27

    Could anyone make this same speech today without getting cancelled?

    • @PurpleAcidRain04
      @PurpleAcidRain04 4 місяці тому

      No. Men and women are not the same and life starts at conception. Thanks for coming to my TED talk

  • @saltyoldwoman
    @saltyoldwoman 8 років тому +56

    It's about time people started studying this. I think a lot of us out there have suspected this type of thing for a long time.

  • @SeanBMusic
    @SeanBMusic 10 років тому +284

    Came here to learn about why the act of sex matters, but thankfully found this to be a fairly interesting talk.

    • @carfreelori
      @carfreelori 9 років тому +17

      yes I thought the topic was about sex and sexuality being healthy for humans. But the talk was a topic I'd find interesting though I thought the title was purposely deceptive.

    • @Bassjojo973
      @Bassjojo973 6 років тому +1

      9. Les hommes qui ont écrit la Bible étaient-ils honnêtes ? Qu’est-ce que cela montre ?Jean B

    • @fredthomson8941
      @fredthomson8941 5 років тому

      Still taking notes and texting in class

  • @vichkovski
    @vichkovski 10 років тому +33

    this is a great presentation. i can only imagine how great a teacher this guy is. the genetic test i bought actually verified a few things that i was previously told by a doctor and counselor

  • @Zura_Lanch
    @Zura_Lanch 5 років тому +103

    He is a very good orator, every word is delivered, important thing especially for non native English speakers.

    • @ejazjan6774
      @ejazjan6774 3 роки тому

      Xxxxxxxxxxxx

    • @AlmostaFlipinSkater
      @AlmostaFlipinSkater 3 роки тому

      I’m sure his wife thinks he’s a great orator too

    • @Zura_Lanch
      @Zura_Lanch 3 роки тому

      @@AlmostaFlipinSkater are you absolutely sure or just a little bit?

  • @bobjeaniejoey
    @bobjeaniejoey Рік тому +8

    Excellent, superb presentation!
    Mr. Page had my rapt attention throughout. His clear diction, and the pace of his phrasing, allowed my layman's mind to easily fully comprehend every point that he was putting forth.
    Now, almost ten years after this talk took place, I'm first hearing of this concept.
    That makes me wonder how much progress has been made in the field.
    It makes 100% absolute sense.
    I will be talking about this subject with others and researching it further.
    Thank you very much, Mr. Page.

  • @emocionycambio
    @emocionycambio Рік тому +5

    Thank you very much for expressing in a simple and direct way what many laymen know without being able to qualify. Now the important is to convince doctors of the advances and new challenges. It has been very gratifying to listen to an expert and great communicator. Really necessary. Thanks again!

  • @pinewood6340
    @pinewood6340 2 роки тому +3

    I don't understand how this only has 2M views after 8 years. It seems like no one has listened to this man. Men and women are still suffering from these diseases without much progress.

  • @Towik
    @Towik 4 роки тому +31

    Not sure why but after watching (mostly listening) i feel so much calmer...
    But i love it how this person asks certain questions and is not laughed at. like most people that try to better the life or the knowledge about the universe.

  • @truthdispellsallfear.8265
    @truthdispellsallfear.8265 3 роки тому +22

    Excellent talk. I am grateful that at least one scientist is still a thinking man who has the moral fortitude to finally state the obvious.

  • @TA_Tactics
    @TA_Tactics 5 років тому +48

    Men and women are fundamentally different.
    Shocking and controversial.

  • @lucasrock6532
    @lucasrock6532 6 років тому +5

    Very informative and well thought out talk. You definitely raised the bar!

  • @azaramoon4027
    @azaramoon4027 Рік тому +2

    I decided to stay up all night and study different ted talks. its onderflly interesting, and more peaceful to study at night.

  • @mpoimakhetha9345
    @mpoimakhetha9345 6 років тому +78

    I should take this into consideration in my PhD next year, amazing how I or my supervisor never take these things into consideration.Thank you

  • @sayrewilkin-dalby619
    @sayrewilkin-dalby619 3 роки тому +51

    It's recently been determined that autism spectrum disorder is more widely recognized in men because it presents differently in women and girls than it does in men and boys. It isn't necessarily that it's more common in men, but it's often been overlooked in girls and women because doctors didn't know what they were looking for.

    • @fiekelief
      @fiekelief 3 роки тому +6

      Thank you! I think their are some other things wrong with this video. Not saying he is incorrect throughout whole the video.

    • @lindsaykat
      @lindsaykat 3 роки тому +6

      Was looking for this comment. This was a good Ted talk but it makes me also want to hear a Ted talk about how things like diagnoses and seatbelts are designed for the male subject

    • @dominiquehudson8077
      @dominiquehudson8077 3 роки тому +6

      @@fiekelief He also claimed that chimps males share 98% of their DNA with Human males. This is misleading. In reality, if you include indels the number drops to 95% with some conservatives dropping the number down to around 90% when talking about MtDNA comparison. On top of that, while 18 pairs of chromosomes are ‘virtually identical’, chromosomes 4, 9, and 12 show evidence of being ‘remodeled.’ In other words, the genes and markers on these chromosomes are not in the same order in the human and chimpanzee. Chimp's DNA structure is different from human DNA. So I'm not sure why he tried to mislead the audience so badly there.

    • @bobhakken7939
      @bobhakken7939 5 місяців тому +2

      I would say that if it presents differently in women and girls than it does in men and boys, it actually reinforces the concept that Dr. Page is trying to get across, that the XX vs XY combination makes a big difference in all aspects of human health.

  • @mspixiedust100
    @mspixiedust100 8 років тому +15

    I keep forgetting this is about what gender you are, not about how important sex and intimacy are.

  • @joenobody8997
    @joenobody8997 3 роки тому +30

    A little correction: chromosomes don’t carry all the hereditary information. There are mitochondria in the cells also contain DNA, which are only from the oocyte. So in term of hereditary material, offsprings get more from their mothers.

    • @RAIRADIO
      @RAIRADIO 3 роки тому +2

      I dont know.. I am exactly like my dad in looks and calibre and personality.

    • @PayThePirate
      @PayThePirate Рік тому +1

      @@RAIRADIO bruh

    • @Idrisg
      @Idrisg Рік тому

      The mitochondrial DNA accounts for much less than 1% of the total DNA.
      But yeah, you get very slightly more genetic material your mother. Also some certain 'mitochondrial diseases' can only be passed on from a mother to the child.

  • @sydnar347
    @sydnar347 Рік тому +1

    that wasn't what I expected. thanks for sharing

  • @Greentrees60
    @Greentrees60 9 років тому +269

    Being equal is not the same as being identical - we can acknowledge differences between the genders without ranking them

    • @dion789
      @dion789 9 років тому +50

      Well, maybe he could have phrased it better, but he is correct. He is not saying that people should not consider men and women socially equal, he is basically saying that diseases don't treat them equally.

    • @user-ti1cj3xq9g
      @user-ti1cj3xq9g 9 років тому

      R5reee! 56zà

    • @sonia8846
      @sonia8846 9 років тому +12

      Men and women are equal when it comes to who they are. They both are spiritual beings , They been programmed to perform different task in life.

    • @nuchinuchitekton7730
      @nuchinuchitekton7730 7 років тому +12

      Equality is a human creation(which doesn't exist anywhere in the universe) , it is synonymous with identical.

    • @essyc4258
      @essyc4258 7 років тому +29

      Being equal means having equivalent value, not being identical. Equal respect in respect of our differences.

  • @TheCheesedodo
    @TheCheesedodo 9 років тому +83

    Most of the people criticising don't even know what the speech was about.

    • @hardcorps5317
      @hardcorps5317 3 роки тому +2

      But they do know that they wasted about ten minutes of their time.

    • @steveunderhill5935
      @steveunderhill5935 3 роки тому +6

      David Page is making a case for using the male/female filter appropriately in our research because it could be impeding our progress.

  • @llshih
    @llshih 9 років тому +53

    I really enjoyed this presentation. The presentation is clearly pesented and intelligent. This talk is about why scientists should take into account the genetic differences in the treatment of diseases. Dr. Page is right that the scientists should not turn a blind eye to this fundamental gender differences when trying to find the treatments for various types of diseases. Some commenters said that the feminists would not like his talk. I said that he is on the contrary trying to debunk the bias held by the male-dominated science community that has tendency to treat diseases from the unisex standpoint (totally ignoring the fundamental differences between xx and xy chromosomes). The outcome of such false medical practices is flawed medical research and practice on the treatment and control of diseases.

    • @nysaea
      @nysaea 7 років тому +9

      I consider myself a feminist, well a "traditional" feminist if you will, and I totally agree with you. This talk was very interesting and underlines very well the sex blindness that is rigging a lot of medical studies, and why it matters that we get rid of it.

    • @alyssamonaco5780
      @alyssamonaco5780 6 років тому

      Robert Henstein Thats very crass its the 21st century.

    • @Alarik52
      @Alarik52 6 років тому +1

      Oh Robert, you've taken the religious approach rather than the scientific one.

    • @meganbrownlee7456
      @meganbrownlee7456 6 років тому

      Beautifully put. His entire point is that our approach to science, specifically the treatment of disease in regard to genetic differences relating to gender, should not be biased based on our social constructs, hence his use of the quote by Bill Clinton. Anyone who is attempting to bring up feminism,or any other cultural philosophies from a place of personal bias in regards to the subject of this ted talk is completely misguided.

    • @j.n.sloane
      @j.n.sloane 5 років тому

      Agreed. Differences may be small but they are important for treatment. I do think that his attempt at humor using the Clintons should have been left out. I also think that saying that men and women are not equal is done provocatively, just as the title was. Men and women are not the same is actually a more accurate statement and scientists should strive for accuracy. Ask yourself if a hammer or a screw driver are equal or the same and you will see how this works.

  • @hsierra50
    @hsierra50 6 років тому +9

    I am surprised to know that medical research has left unnoticed this important difference between human beings. I hope that in recent years that has already been corrected. Great talk Mr Page. thanks a lot for the enlightenment !!

    • @kathleen7849
      @kathleen7849 3 роки тому +1

      That's what I found shocking. How such intelligent people can miss something so essential and I would have thought, obvious.

    • @DataJYdocs
      @DataJYdocs 3 роки тому

      One fundamental notion also never addressed by earthlings is the absence of rut from their own dna/genome (Mammals; Anthropoids; Cro-Magnon, mating season). Which will certainly require a definitive remede, eventually.

    • @CarolinHauser
      @CarolinHauser 3 роки тому +1

      Hi Hugo have you come across the book Cupid's poisoned arrow?

    • @hsierra50
      @hsierra50 3 роки тому

      @@CarolinHauser Hi Carolin ! no ..I guess I should look for it and read it uh thanks for your recomendation ! best regards !!

    • @CarolinHauser
      @CarolinHauser 3 роки тому

      @@hsierra50 yes I highly recommend it

  • @ahmedmuzty3395
    @ahmedmuzty3395 Рік тому +1

    This presentation answer alot of questions I have in mind . Great presentation thanks Ted x

  • @airlopez21
    @airlopez21 9 років тому +269

    So much humility in the comment section.... Get over yourselves people. How many ted talks have you been invited to give? I'm not saying giving a ted talk means you're infallible but most of you have ZERO credibility, other than a PhD in criticism and arrogance. Let go of your egos and try to gain some insight from someone who has devoted decades of their life to developing extensive domain expertise.

    • @way2tehdawn
      @way2tehdawn 9 років тому +5

      I doubt you know the credentials of these commentors, they could be professors or they could be fishermen. You don't know, you are in no position to judge the validity of these peoples points. If you want to do that you should at least look into their backgrounds and fact check what they are saying, of course including references and a bibliography. If not, then I'm afraid you're the one with zero credibility, playaasaaaa!

    • @liwtumrn4
      @liwtumrn4 9 років тому

      tell em, lopez!

    • @VanesssaVoxx
      @VanesssaVoxx 9 років тому +8

      way2tehdawn Hi, I did some research and I found out who this guy is. and he really is an authority in the matter, he is the director of an institute, a professor at MIT, has won several awards in his field and The New York Times and other big magazines give him credit. I hope he makes great breakthroughs in medical biology. So, I appreciate his efforts and those of the TEDx Talks community.

    • @daultonbaird6314
      @daultonbaird6314 9 років тому +1

      Vanessa Voxx l'm amazed that you haven't gotten a + until now . way2tehdawn seems to think they let any bozo with no cred talk . Yeh right .

    • @fatimazohra134
      @fatimazohra134 8 років тому

      +Argentarii Homini , amour, , 6

  • @redmed10
    @redmed10 6 років тому +4

    Misleading title but a tedx talk that actually brought some important knowledge to general public for once.

  • @nrnar
    @nrnar 8 років тому +5

    Great talk. Very interesting. I hope that this discovery will usher in new answers to the myriad of diseases found in man & woman and towards its cure, God willing.

  • @eleonorapole9628
    @eleonorapole9628 3 роки тому +4

    I wonder about 1000 people who disliked this. Great speech and thinking!

  • @rodgeraarons8997
    @rodgeraarons8997 5 років тому +1

    Well that title got this ted talk a lot more attention than normal

  • @darriuscole8544
    @darriuscole8544 4 роки тому +36

    I am amazed that scientist study cells without knowing whether the cells are male or female. That should be the first thing in the label when the cells are collected.

    • @lorahansen1783
      @lorahansen1783 3 роки тому

      Probably done to eliminate scientific bias.

  • @xgodram
    @xgodram 11 років тому +15

    this man is amazing..you rock sir

  • @jamesmusaali84
    @jamesmusaali84 10 років тому +8

    Really worht watching I have known this all the time since I was growing up I think that it is commendable the research world starts their focus with these insights. Dr Page good work.

  • @TeamCuellar
    @TeamCuellar 10 років тому +19

    Didn't think it was boring at all. I wish more people on this level of intelligence would also think outside the box. We might get a lot more accomplished.

    • @joaquimpedro3267
      @joaquimpedro3267 10 років тому +2

      He is a perfect example of an inside the box thinker. In the statistics interpretation he ignores completely sociocultural effects of the culture of dividing people in genders, wich is the most logic explanation for the data he presented since the different genders have different behaviours wich will lead in the statistics to different responses in health to certain diseases, or even a general difference. This difference is observable and may be tested since not everyone of the same gender has the same biological sex, thefore the hipothesis 0 should be that the correlation is socially caused, meaning that he should first prove it is not socially caused and just later sugest that is is caused by some factor that is different between biologic sexes, wich might or not be the X Y chromossomes. He said that the answer he hears the most when asking people the reason of the statistical difference he presented is "i don't know", so he obviously must be ignoring all te explanations or even not looking for answers from people who understand what he is showing, probably both. He is just intellectually disonest and obcessed with proving right his sexism.

    • @klick08
      @klick08 10 років тому +2

      Joaquim Pedro I'd have to disagree, why? I'd like to think that in the process of trying to determine why women and men suffer from disease A or B differently, that the researchers have examined the lifestyles and habits of the individuals they are studying as well as the environment they find themselves in and as such, would have taken into account the differences presented by gender divisions either knowingly or unknowingly. It wouldn't make sense to try and determine why there are differences otherwise. So, your argument that socio-cultural effects of dividing people up into genders is the root cause should already be off the table, unless you are saying that merely associating yourself with a gender will make you more susceptible to one disease.
      So, yes, what he's doing would be considered outside the box thinking. He's considering a possibility that people are overlooking in a situation where all possibilities should be looked at.
      He actually was not being sexist, he clearly knew the impact of saying men and women are not equal and did that for dramatic effect. I'd argue that YOU were being sexist by inferring that he was being sexist merely by stating that there might be a genetic reason behind women and men having different affinities for certain diseases.
      It'd be stupid not to look into something simply because it points out one of our few differences, after all, a difference does not make one thing or the other better.

    • @joaquimpedro3267
      @joaquimpedro3267 10 років тому

      klick08 He showed a correlation between gender and response in life expectancy given a disease, nothing else. Using a method for eliminating the sociocultural effects of gender is really important, since those effects obviously exist, after all everybody knows that different genders have different healths, and the biological sex is ALWAYS attached to gender or to many gender related values. With this in mind what becomes really important in his research, what gives it validity is the quality of this specific methodology (and you seem to agree with me, since you said you’d like to believe he used it). He has to present it, otherwise it is the same as no research at all since the difference in health he presented is already wkown by everyone, everybody knows men and women’s health are different.
      He didn’t even bother to suggest having considered those factors. And even if he had considered, the efficiency of this methodology would rely on knowing EXACTLY what are the sociocultural factors that are influent, and that is almost impossible. He could never guarantee to have covered everything. He could only try to suggest some correlation after intensely refining this methodology, observing changes in results according to changes in it. And, obviously, the methodology must always be presented.
      You would be very much surprised to know how much, willingly or not, this kind of bad or absent methodology convinces loads of people of invalid conclusions based on utterly meaningless data just because they “would like to believe” something; because as there are people who would like to believe something there are researchers who would like to convince people of something. And some would like to convince people, and/or themselves, of the supposed results either for notoriety or to rationalize a personal belief. Scientist are people too.
      Wich takes me to this: You said, “...he clearly knew the impact of saying men and women are not equal and did that for dramatic effect”. You take this as an evidence that he is NOT sexist? You think he wanted to be dramatic to alert people of the social dangers of saying things in a stupid way like he is doing, or what?
      Other thing: “...unless you are saying that merely associating yourself with a gender will make you more susceptible to one disease.” Men and women have different behaviours, wich will lead to different healths, be it as a response to a given disease or as susceptibility to a disease. So, yeas, associating a person with a gender will dictate the behaviours wich will change health. That’s the whole point of sorting out the socioculturally caused difference.
      And i believe by now you have understood that i’m not “inferring that he was being sexist merely by stating that there might be a genetic reason behind women and men having different affinities for certain diseases”. I do believe those differences must be considered when proven to exist, and there must be research about this matter. The only thing i’m saying is that he didn’t show anything that should convince anyone of what he is willing to convince. Actually the fact that he couldn’t find any evidence of it only makes me think that there are actually less difference than people think. Research in this subject is not sexist, but the sexism suggested by his attitude was just the most probable reason to have led him to make this research.

    • @fredthomson8941
      @fredthomson8941 5 років тому

      Hard to think if you're snoozing

    • @rawr6306
      @rawr6306 3 роки тому

      @@joaquimpedro3267 OMG... So if I were to have been dressed up in girls clothes from an early age, played with dolls, stayed home with the kids, washed the dishes & floors and had the occasional “girls night out” I’d be more likely to contract RA or Lupus than “men”? Right... 🙄🤦🏻‍♂️🤦🏻‍♂️🤦🏻‍♂️ (btw. I’m XY if that matters... 😏)

  • @Joannabanana1989
    @Joannabanana1989 3 роки тому +1

    This is a very informative video! I learned a lot!

  • @SpeedSeekerMoto
    @SpeedSeekerMoto 4 роки тому +32

    Wow, this is very intresting. I was really grabbed by the fact that students studying human cells dont even know if they are male or female. Very intresting. Has there been any progress on this comprehension in the science community since of the bilogical diffrence?

  • @davidjefferis4467
    @davidjefferis4467 4 роки тому +1

    A clear and fascinating discourse. Thank you.

    • @CarolinHauser
      @CarolinHauser 3 роки тому

      have you come across the book Cupid's poisoned arrow?

  • @Loppy2345
    @Loppy2345 8 років тому +241

    Lol at all the people complaining because they don't realize that the word sex can have more than one meaning.

  • @rosebw1077
    @rosebw1077 3 роки тому +2

    God finally I hope this man is going to save so many lives if people will only listen

  • @Deni-ck9bl
    @Deni-ck9bl 3 роки тому +2

    This is brilliant and this man is a genius .

  • @brianzl4885
    @brianzl4885 Місяць тому

    Wow, superb talk. Thank you.

  • @janviiic
    @janviiic 10 років тому +9

    I think that's precisely why he used such a wording, to provoke people and keep them interested in the important things he's said. It's really just a matter of capturing interest.

    • @onniborg9065
      @onniborg9065 3 роки тому

      I think so too and in my opinion, it's important to notice that this is a very specific subject.

  • @georgeflitzer7160
    @georgeflitzer7160 Рік тому

    Ty loved this presentation though it was done 9 years ago. Ty!❤

  • @ronszera9749
    @ronszera9749 10 років тому +26

    when genius + creativity = this man.

  • @otmarkastner1
    @otmarkastner1 3 роки тому

    Thank you, David 👋

  • @CarolinHauser
    @CarolinHauser 3 роки тому

    Thanks for this video!

  • @vijaysabnis7291
    @vijaysabnis7291 3 роки тому

    Very articulate and brilliant.

  • @MsGnor
    @MsGnor 10 років тому +20

    I loved the close-up of the X and Y chromosomes. Will be interesting to hear what XY/XX researchers come up with.
    Drug trials on humans are done with mainly male volunteers aged 18-35. This is to avoid potential harm to female reproductive organs.

    • @birthekjaersman4241
      @birthekjaersman4241 9 років тому +8

      No, it is not. It is because women reacts differently to the same dosis/kg bodyweight. If I, weighing at present 64 kg, takes 3 6cl-schnappses, I will be more than tipsy, I will be drunk. If a man weighing the same, takes the same amount of alcohol, he may not be tipsy, but he will be much less drunk.
      There are at least two reasons for that:
      1) Men have a larger percentage of water in their bodies.
      2) Men's livers work faster breaking down alcohol than women's.
      Many medicines behave similarly. So, to make thing easier (and cheaper!) for those who do drug trials, they have used men. Which does NOT make things easier for the women who later on uses the medicine. That is why women have a higher rate of unwanted side-effects from drugs. Those who do their research says: - But they work just fine with men!

    • @MsGnor
      @MsGnor 9 років тому +5

      Maybe that's true Birthe - I can't say. I worked at a drug lab; the doctors told me that protecting women's reproductive organs was the reason they mainly use men instead.

    • @birthekjaersman4241
      @birthekjaersman4241 9 років тому +4

      That's just silly. Don't the men's reproductive organs need protection too?

    • @MsGnor
      @MsGnor 9 років тому +3

      Hi Birthe
      I worked at the drug unit about 10 years ago so I'm not sure of their current policies. While I was there women did participate in trials but most were conducted on men. I remember I was given reasons along these lines (pasted from article):
      "There are also historical reasons for excluding women, particularly those in their child-bearing years. In the 1950s, the sedative thalidomide caused pregnant women to give birth to babies with missing limbs, and DES, an estrogenlike drug prescribed to prevent miscarriages, increased the risk that female babies would develop rare vaginal cancers later in life. When these findings came to light, clinicians and drug companies became cautious. "There was this worry: What about women who might get pregnant?" says Ruth Faden, executive director of the Johns Hopkins Berman Institute of Bioethics."
      I've included the full article (see link below). It discusses reasons for excluding women and why that might be harmful. Very interesting.
      Drug Problem: Women aren't properly represented in scientific studies
      www.slate.com/articles/health_and_science/medical_examiner/2010/07/drug_problem.html

  • @Exotic3000
    @Exotic3000 3 роки тому

    This was very informative!

  • @gabrielarathlinares982
    @gabrielarathlinares982 3 роки тому +3

    Super interesting specially now that we see the difference of the severity of covid between men and women 👍

  • @PurpleAcidRain04
    @PurpleAcidRain04 4 місяці тому

    Amazing how 10 years ago it was understood that men and women are different. “Men and women are not the same, life begins at conception. Thanks for coming to my TED talk “

  • @atthehops
    @atthehops 11 років тому +2

    This is such interesting research that results in profound questions. More people, and doctors especially, need to hear about the differences between X & Y.

  • @kt-pp2ei
    @kt-pp2ei 10 років тому +1

    Wow, such a fundamentally obvious point. Good info.

  • @iwnunn7999
    @iwnunn7999 9 років тому +14

    If you are not in the arena with David Page or anyone else, you have no right to criticize. If you are in the "arena", give him feedback that's useful.

  • @raaghsRajput
    @raaghsRajput 9 років тому

    appreciate the work...

  • @Exceltrainingvideos
    @Exceltrainingvideos 9 років тому

    Fascinating...

  • @Aviforevolution
    @Aviforevolution 5 років тому

    great talk sir.

  • @malitaus5672
    @malitaus5672 Рік тому

    Super interesting, thank you.

  • @joaoavf
    @joaoavf 10 років тому +1

    Congratz! Great work!

  • @IBRAHIMATHIAM124
    @IBRAHIMATHIAM124 8 років тому +1

    great talk !

  • @joseperurena2770
    @joseperurena2770 5 років тому +1

    Excellent!!!

  • @javeriasiddiqui9781
    @javeriasiddiqui9781 10 років тому

    great research.

  • @matrix5025
    @matrix5025 10 років тому +25

    Disease is not merely reflection of genetics. For a professor at MIT, I'm surprised he does not acknowledge the obvious counter-argument to his presentation : that disease, just like any trait for that matter, is mixture of what is ACQUIRED and what is INNATE. Life experience, societal upbringing, gender roles, behavior, have probably as much impact on us and our health - as do our chromosomes. Granted, it's true "we don't know" to a full extent what causes disease, but the fact that we have men with rheumatoid arthritis, or females with autism kind of makes me wonder just how the X versus Y "theory" of disease has any relevance... Just my thoughts. Still a fun to watch, nice presentation.

    • @richpersoff4080
      @richpersoff4080 10 років тому +3

      With eight minutes, he could hardly have given much time to counter arguments.

    • @TheRealFufuchs
      @TheRealFufuchs 10 років тому

      How can you not mention diet as a factor for health when we know that the consumption of animal products promotes cancers?

    • @BunnyOfElvnteenlives
      @BunnyOfElvnteenlives 10 років тому +1

      Frederik Dortmund
      Because he has eight minutes and his topic was not "Why you should be a vegetarian"

    • @santhorwei
      @santhorwei 9 років тому

      and rheumatoid arthritis can be contributed due to the lack of exercises especially in the form of resistance training ie. body weight training; weight lifting; career related as no woman would carry no heavy shit ever at their job. (giving their bfs the grace of carrying their shopping bags). How can we say this is gender related due to nature and not NURTURE? he should at least address this. Women are susceptible to osteoporosis(weakening of bone density) than men due to calcium absorption at older age however, it is not significant to show the disparity between the statistic.
      However his talk about why diseases should be treated with women and men, getting more informations about cancers and diseases would be a very good resource for understanding illnesses and the field of epidemiology. However his presentation was not that related. However i enjoyed the pictures of the chromosomes

    • @Lindathemightywitch
      @Lindathemightywitch 7 років тому

      Constantin Filip Woah.. Preach on brother!

  • @robotaholic
    @robotaholic 6 років тому +11

    His microphone is shaped funny lol

  • @anjalibriel1266
    @anjalibriel1266 4 роки тому +3

    This has been truly fascinating, to know what research is currently being conducted, and on what basis. Without your very valuable input, we would never have known - So thank you very much for educating us! The Indian Ayurvedic system of medicine treats people according to the 4 elements, in terms of our body types, what we prefer to eat, and have even mapped out very accurate personality profiles according to each element - air, fire, water and earth. It's also so inspiring when Eastern and Western health experts share their expertise, and knowledge that's often 1000's of years in the making!

    • @CarolinHauser
      @CarolinHauser 3 роки тому

      have you come across the book Cupid's poisoned arrow?

  • @neththom999
    @neththom999 6 років тому +10

    Haven't seen this one in a while. Figured it would have been banned by now.

  • @theonlyjamiebourgeois9703
    @theonlyjamiebourgeois9703 5 років тому +1

    BIG thumbs up

  • @1blessedsavior
    @1blessedsavior 5 років тому

    Amazing!

  • @TheSaraeanderson
    @TheSaraeanderson 8 років тому +31

    My intuition is that autoimmune disease is a lot more prevalent in women because pregnancy is a weird process for the immune system.

    • @ruthannjones5873
      @ruthannjones5873 6 років тому +4

      Sara Anderson
      Interesting. It's certainly a valid consideration.

    • @shirleycolee1
      @shirleycolee1 5 років тому

      Wow. How smart. This should be pursued.

    • @sallyblack414
      @sallyblack414 5 років тому

      Whoa. That made me stop and think. Awesome comment!

  • @pamelahuling-jordan7274
    @pamelahuling-jordan7274 7 років тому +12

    this seems like common sense. The Y chromosome is not dormant in nonsex organ cells. The proteins produced by the Y chromosome are not just male hormones. Males and females present different symptoms for some of the same medical conditions. They respond differently to some medicines that are not know to interact with sex hormones. It is also known that children and adolescents do not always have the same symptoms of some disease or do not react to medicines the same as adults. Different genes are active to different degrees at different ages. Surely those genes are not only the genes for sex hormones? Could some of the differences also be from our wanting to simplify our understanding of the human genome?

    • @optimisticallyskeptical1842
      @optimisticallyskeptical1842 5 років тому +2

      Yes. It comes from human ability to be lazy and take shortcuts that turn out to be a stumbling blocks to good science and good practices. It seems researchers, for whatever insane reason, decided to dismiss the XX/XY variable in their work. That cannot be said for all research, but it seems to be the case in genetics if this speaker is correct in his conclusions. The real question is: Was it politics that caused the ignorance or just simple human error?

  • @thankgodwilson1142
    @thankgodwilson1142 7 років тому

    very intelligent topic

  • @charlesbrooks2051
    @charlesbrooks2051 5 років тому

    Very interesting!

  • @SleepEatWorkRepeat
    @SleepEatWorkRepeat 10 років тому +3

    How could anyone dislike this video? Very eye opening...

    • @HJC1950
      @HJC1950 3 роки тому

      Probably pissed off those pushing their woke BS like lots of multiple genders rather than XX and XY...

    • @jasonwiley798
      @jasonwiley798 Рік тому

      @@HJC1950 there are cases of xxy and xyy. What gender are these people.

    • @HJC1950
      @HJC1950 Рік тому

      @@jasonwiley798 Who cares? What percentage of people fall into those categories?

    • @jasonwiley798
      @jasonwiley798 Рік тому

      @@HJC1950 my point is there are more than 2 biological sexes. It isn't as simple As you would love me it to be

  • @JuliaRingma
    @JuliaRingma 4 роки тому +18

    It seems kind of obvious that the XY chromosomes would make a difference to the entire person, especially when you consider the things that go wrong in people with XXX and XXY and other mutations of the XY set. I'm amazed they haven't thought about this before now.

  • @lhedralkhawya
    @lhedralkhawya 3 роки тому +16

    I thought everyone already knew this.

  • @carmensierra3935
    @carmensierra3935 7 років тому +2

    i had no idea they werent taking that into account! how bizarre! that is obvious.

  • @erinfreeman4367
    @erinfreeman4367 4 роки тому +12

    This is fascinating. It makes me curious about the effects of hormone treatments in people that are transitioning in relation to their biological xx or xy chromosomes.

    • @orenjineko646
      @orenjineko646 4 роки тому +2

      Already happened before, mid 80 - late 90, lots of athletes were using anabolic steroids (dope). This thing causes all kind of problems, changes people hormones - have different effects between men and women.

  • @babuOOabc
    @babuOOabc 9 років тому

    I say that everything is important and priority depends on
    HOW THAT AFFECTS YOUR LIFE? OF WHICH MAY NOW WHAT WAS IMPORTANT IT IS NOT SO DEPENDING ON THE CIRCUMSTANCES .

  • @1lightdweller
    @1lightdweller 7 років тому +39

    It would be interesting to examine people who have had organ transplants from one gender to another in this regard.

    • @kasmozaydn2734
      @kasmozaydn2734 6 років тому +1

      1lightdweller h

    • @ya472
      @ya472 5 років тому +5

      What about blood transfusions ? xx or/and xy cells

    • @englishgalmd
      @englishgalmd 5 років тому +16

      @@ya472 Red blood cells don't have a nucleus in human beings or in other mammals. So it wouldn't have any nuclear DNA. It also loses is mitochondria so it doesn't have that DNA either.

    • @DennisCrow
      @DennisCrow 3 роки тому

      @@englishgalmd How do they get DNA from a blood sample?

  • @dianesmith4111
    @dianesmith4111 3 роки тому +2

    His presentation makes common sense. As a female, that is why I prefer a female primary care provider. Female Drs. have a much better idea/experience dealing with female patients. They are one.😊

  • @karaoke.memphis
    @karaoke.memphis 2 роки тому

    Did he say 'ill-ease?'
    Talk clinical courteous candor aptitude ability.. social competencies. Great lay presentation reception expected. Fact, science pertinent-base discovery.

  • @noah8236
    @noah8236 2 роки тому

    Very interesting points for Rheumatoid Arthritis and Autistic Disorder.
    Yet I have to dismiss the third example of disease.
    It's never Lupus.

  • @meganbrownlee7456
    @meganbrownlee7456 6 років тому +2

    I think this talk was incredibly well presented, and here`s why. Beginning with the quote from Bill Clinton, he illustrates the ways in which our cultural environment can influence, perpetuate, and also benefit from social constructs. Such as, equality across gender and race. The negative aspect of this is that it has biased our scientific approach. However, the benefits of our social ideologies are becoming apparent *as well* because it indicates that while our social environment is promoting equality of life and experiences regardless of gender, we are now seeing despite this environment of equality there remain unexplained differences between genders which we can now approach from a scientific perspective.

  • @patrickmuleega1506
    @patrickmuleega1506 Рік тому

    It's a very good teaching but to some of us who are not so sciencertific we find it hard to translate some words

  • @sheltondk43
    @sheltondk43 9 років тому +3

    Very interesting and provoking of curiosity and study.

  • @vg1973
    @vg1973 3 роки тому

    It would have been useful to compare the differences in diseases etc. across the spectrum of animals and other organisms.

  • @pharmclare
    @pharmclare Рік тому

    Interesting insights

  • @briejoana.6736
    @briejoana.6736 5 років тому +1

    we found that out quite late….congratulations still !!!

  • @DrewSchroeder22
    @DrewSchroeder22 9 років тому +144

    this title tricked me :/

    • @smallheelcatcher
      @smallheelcatcher 6 років тому +7

      hehe. It tricked me too, but I am into genetics and relationship stuff both. So, I'm glad I clicked.

    • @ShaferHart
      @ShaferHart 4 роки тому

      @@smallheelcatcher guess I can safely skip this bs lol thanks!

    • @paintitblack6728
      @paintitblack6728 4 роки тому +1

      @@ShaferHart And that is the why you are an uneducated moron. END OF!

  • @calmdev1577
    @calmdev1577 9 років тому +2

    How amazing that 10 trillion cells communicate wireless. What he said makes sense.

  • @abbiet22
    @abbiet22 9 років тому +41

    Why are we so uptight about this? This isn't about feminism. That was a poetic license, phrases used for a rhetorical effect that'll pique your interest. This TEDx talk is thought provoking as it should be. Just like how we address vulnerability of a race towards some diseases. Judging racist or sexist wouldn't help you with breakthroughs of how we view health and/or treat diseases. Let's be pragmatic for once.

  • @TheCoExister
    @TheCoExister 3 роки тому +1

    Anatomically higher levels of testosterone can help prevent arthritis. In fact most of his questions I would say the persons hormones and imbalance in those hormones over a lifetime often can cause disease. Beyond that for the same gender at the same time, a different lifestyle changing the results greatly

  • @wescombs8311
    @wescombs8311 8 років тому +210

    Guys if you watch this on 2.5x speed he talks like a normal human.

    • @nyahbell826
      @nyahbell826 8 років тому +21

      thank you! hahah i only went up to 1.5 but it made a huge difference hahah

    • @ramixnudles7958
      @ramixnudles7958 7 років тому +9

      You must have a better youtube than I do. I can only crank mine up to 2x.
      I find that most of the ADHD videos are easier to watch at > 1x.
      2x is only the beginning. In the perfect world, we'd be able to crank it up to "11".

    • @Jasmine-uw3sn
      @Jasmine-uw3sn 7 років тому +16

      WTF THANK YOU!!! Ya boy was talking in grandma miles per hour.

    • @Sean-dl8ym
      @Sean-dl8ym 6 років тому +1

      Hahaha I thought I was the only one who did this!!

    • @artscraftsantiquity2185
      @artscraftsantiquity2185 6 років тому +1

      Omg! Thank u!!!

  • @miguelleonelgranadospeguer2371
    @miguelleonelgranadospeguer2371 4 роки тому +2

    As a physician I agree, receptors and its reaction to stimuli is gender dependent, take pain as example

    • @miguelleonelgranadospeguer2371
      @miguelleonelgranadospeguer2371 4 роки тому

      @Nikki Pettway The threshold of pain is not the same (valid paper science) which concurs with the data on the video

  • @nshalom12211221
    @nshalom12211221 9 років тому +1

    wow
    im not a professional but this concept can be really groudbreaking if its true

  • @beatles925
    @beatles925 7 років тому +2

    This is so fascinating!

  • @SidraNeelum
    @SidraNeelum 7 років тому +14

    Absolutely informative! Thanks tedX :D

  • @hollandhollywood329
    @hollandhollywood329 4 роки тому

    I expect the idea to be developed early on as to why the Y chromosome is so different.

  • @donnaritchie5995
    @donnaritchie5995 5 років тому

    xy vs xx makes a difference as to what therapy to prescribe. What about blood grouping? Does the difference of blood type make a difference to how we should be treated for disease?

  • @sabaof8
    @sabaof8 3 роки тому

    Superb.

  • @BlondeQtie
    @BlondeQtie 3 роки тому +1

    I am in biomedical research and I have never been taught that the Y chromosome is only affecting the reproductive system. The differences in diseases have always been accounted to the chromosomes in my circles.

    • @laurahorehled5494
      @laurahorehled5494 3 роки тому +1

      Good to hear. I don't know how long you've been in the field but this talk was 8 years ago and maybe why you do it differently now.

  • @shelbysmithvigil7844
    @shelbysmithvigil7844 5 років тому +6

    Wonder why it's taken so long to recognize this

    • @CarolinHauser
      @CarolinHauser 3 роки тому

      have you come across the book Cupid's poisoned arrow?