Neurobiological mechanisms underlying ketamine's antidepressant effects - Samuel Kohtala

From receptors to networks - Samuel Kohtala, PhD, MSc (Weill Cornell Medicine, NY; University of Helsinki), provides an overview of the neurobiological mechanisms underlying ketamine's antidepressant effects. Classic psychedelics may be making their way into psychiatric treatment in the next few years. But the psychedelic-like dissociative ketamine is already there, being actively used especially for treating depressive symptoms. How is it able to reduce depression so rapidly?
This talk was originally presented as part of the Ketamine in Psychiatry online seminar, organized by the Finnish Association for Psychedelic Research on January 20, 2021.
See Dr. Samuel Kohtala's UA-cam Channel for more fascinating videos on brains and drugs: / neuropharmacist
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The Finnish Association for Psychedelic Research is a multidisciplinary association founded in December 2016 with the goals of promoting scientific research related to psychedelics and the availability of accessible information based on such research.
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[@starlightpancake]

Ketamine therapy saved my life

[@Eflodur]

Interesting that I found this vid on ketamin so late.
One of the best videos out there.

[@thezzach]

I am a Veteran with severe PTSD & chronic depression. I’m watching this 1 hour after taking 100mg of ketamine + 6 hits of cannabis. They complement each other by recalibrating my brain for 1-3 hours at a time.
14:00
21:00 return to baseline ~10 days post ketamine treatment.
My return to baseline after 300mg 3 hour ketamine infusion is around 3 days but the VA will only give me the infusions once every 6 weeks.
22:30 Crucial importance of Sleep after ketamine 👌
24:30 Sleep is the price of plasticity

[@thezzach]

21:55 if the dendritic spines are restored, why do the depressive symptoms return?

[@Teawisher]

Kiinnostava aihe. Ehkä tästä löytyy vastaus siihen nostaako ketku myös niiden mielialaa jotka on jo valmiiksi hyvinvoivia.

[@tonipaavola2413]

Mun kokemuksien pohjalta voisin sanoa että nostaa. Mitään kummempaa ei ole tarjota kuin mutu tuntuma asiasta.