I'm 2 weeks away from step 1 and I just discovered your videos. My only regret is that I didn't discover them sooner. You have an amazing way of breaking down complex topics into easy to understand information. Thank you for taking the time to make these videos!
Nice explanation, but make sure to clarify that the DO2 calculation should include multiplying CaO2 X 10dL/L to get units to align with those of cardiac output which is in L/min
So, I'm just starting med school and I thought this topic was going to be super hard BUT I actually understand!! And I haven't even covered this in class as yet. Either I'm super smart or youre really good!! (Smile)
Instead of "measures" the correct word would be "affects." Thus Partial pressure of O2 affects the amount of O2 dissolved in the plasma and the O2 saturation of the inspired air affects the amount of O2 bound to the hemoglobin in the RBC.
Thank you for your excellent lectures. In regards to the last question, I believe factors HR and SV, which are outside of the parenthesis, have a higher influence than Hgb, as they are being multiplied by two factors in the parenthesis. For example: 2 * (4 + 1) = 10 Increasing the 2 by 10%: 2.2 * (4 + 1)= 11 Increasing 4 by 10%: 2 * (4.4 + 1)= 10.8
Thanks for your awesome videos. I just have a question,what will be happened to H+ ions (that comes from dissociation of H2CO3) as they are transported toward the lung ?.
They will join side chains of amino acids in the polypeptide chain in the haemoglobin rendering it more acidic and decreasing the affinity for O2 more.
No, increasing the partial pressure of O2 does not increase the O2 saturation, its concentration proportional to the other gases in the air would remain unchanged, I think typically 21%.
If yo u want to deliver more oxygen to your plasma, you could get high oxygen concentration in a hyperbaric environment. If you get inside a hyperbaric chamber at 3 ATA you will get 22.6 times more oxygen dissolved in plasma; so, you could get all the oxygen for restoration and renew cells and blood vessels. What is your opinion? What you think is extremely important for me!!
Sure. But what happens at the far end? Does plasma give up its O2 and pick up CO2 as efficiently as hemoglobin? I suspect the 0.0003 factor is an indication of how difficult it is to get O2 in the plasma released/exchanged for CO2.
Thanks for the comment- glad to hear the video was helpful.
Nursing student appreciates the simplistic explanation of complex concepts. Thanx
Your videos are perfect for the physiology level we are learning in Respiratory therapy! Thank you so much for your time
I'm 2 weeks away from step 1 and I just discovered your videos. My only regret is that I didn't discover them sooner. You have an amazing way of breaking down complex topics into easy to understand information. Thank you for taking the time to make these videos!
+Brandon Rosenberg Thanks for the feedback and best of luck on step 1
May I ask you how did u do? hope you did great.
So well explained. Clear as crystal.
Thank you!
preparing for usmle step 1..ur videos are useful to me in understanding the concepts..thanks a lot.
thank you! you are the man!
Excellent explanation.thank you very much .I am a professional anaesthesiologist in Pakistan.keep it up
Its very clear to me now
Thank you
Very very nice, these videos will certainly help me for revision. The question at the end is also very useful
this was very useful! thank you!
Wow, thank you
great lecture 🙂
This lecture was phenomenal.
Amazing
WOW! I FINALLY GET IT! THANK YOU
Excellent!
Nice explanation, but make sure to clarify that the DO2 calculation should include multiplying CaO2 X 10dL/L to get units to align with those of cardiac output which is in L/min
The one question that I really had. Thank you!!
This is so good. From a med student going int to anesthesia -- thanks!!
William Yates Thanks for the feedback, and best of luck with your anesthesia training
Thanks a lot for these excellent lectures. I'd like little bit longer.
Perfect.
Nice.amazing.crystal and clear
i wish you were my lecturer. thanks!
Would you be able to do one on lab values that would be awesome and thanks for your videos
Thank you for clearing up these concept.
Mohanned Alnammi You are welcome- thanks for watching
Really this video lecture is a academic one, very much illustrative , understandable so useful for the clinical practice. THANKS.
Very nice, cheers.
So, I'm just starting med school and I thought this topic was going to be super hard BUT I actually understand!! And I haven't even covered this in class as yet. Either I'm super smart or youre really good!! (Smile)
Thanks, I liked the last question
excellent videos
Thanks a lot Sir,
well, can I say that pao2 measures the dissolved o2 in the plasma and saturation measures the o2 in rbc?
Instead of "measures" the correct word would be "affects." Thus Partial pressure of O2 affects the amount of O2 dissolved in the plasma and the O2 saturation of the inspired air affects the amount of O2 bound to the hemoglobin in the RBC.
exellent
Thank you for your excellent lectures. In regards to the last question, I believe factors HR and SV, which are outside of the parenthesis, have a higher influence than Hgb, as they are being multiplied by two factors in the parenthesis.
For example:
2 * (4 + 1) = 10
Increasing the 2 by 10%:
2.2 * (4 + 1)= 11
Increasing 4 by 10%:
2 * (4.4 + 1)= 10.8
You are right, but the Partial pressure factor only adds an additional 0.3% to the end result, so ≈ insignificant.
you are a boss
I picked Hb as the answer, now to check if I'm right.
Thanks for your awesome videos. I just have a question,what will be happened to H+ ions (that comes from dissociation of H2CO3) as they are transported toward the lung ?.
They will join side chains of amino acids in the polypeptide chain in the haemoglobin rendering it more acidic and decreasing the affinity for O2 more.
Wouldn't increasing PaO2 by 30% also achieve higher SO2 and thus contribute to oxygen delivery from the hemoglobin side of the equation as well?
No, increasing the partial pressure of O2 does not increase the O2 saturation, its concentration proportional to the other gases in the air would remain unchanged, I think typically 21%.
Please do not use purple / violet color on black board.cant be seen properly.
If yo u want to deliver more oxygen to your plasma, you could get high oxygen concentration in a hyperbaric environment. If you get inside a hyperbaric chamber at 3 ATA you will get 22.6 times more oxygen dissolved in plasma; so, you could get all the oxygen for restoration and renew cells and blood vessels. What is your opinion?
What you think is extremely important for me!!
Sure. But what happens at the far end? Does plasma give up its O2 and pick up CO2 as efficiently as hemoglobin? I suspect the 0.0003 factor is an indication of how difficult it is to get O2 in the plasma released/exchanged for CO2.
Dear@@petep.2092 ,
I only said: the way you could deliver more oxygen, nothing else!