Thank you SO much for that info on vortioxetine + bupropion! I’ve been looking everywhere for data on combining them (given their interaction) and now I know the suggested max of vort is 10mg in combo. Can you PLEASE cover Vortioxetine in a stand-alone video? It hits so many receptors and it’s so interesting.
Okay with the Jung deep end joke I had to log in and say: good channel good sense of humor I loved psychopharm (basic, wikipedia) when I was in my late teens and doing drugs, and now I'm in my late 20's trying to find a way to not kms using a lot of the same knowledge and the help of my psychiatrist. Thank you
My doctor said that, Wellbutrin inhibits more dopamine than noradrenaline. He said actually it's very week noradrenaline inhibitor. Instead of noradrenaline it works on dopamine. This is what my doctor said
As far s i know its the other was around. It inhibits more Norepinephrine ans lesss Dopamie. Thats why the D is on second place, while the N is first NDRI.
Thanks! Simply said.. Sorry for grammar errors, i am from Europe. In my country we still do not have so many variations of the drug as bupoprion.., actualy we have only wellbutrin. For now ... Thanks for all information and education. Most important is what U say at the end of the video. For me, at least... Thanx and b.ok
In following on from the moa diatribe, if you look at the effect of antiseziure drugs as mood stablisers, is it then assuming wrong that an ndri with seziure risk is contraindicated for bipolar mania 🤔 Also I saw somewhere that Bupropion increases plasma levels of reboxetine multiple fold but it wasn't the best source and you won't find it in the literature. Make of that what you will but worth putting out there. Ritalin isn't used as antidepressant anymore. I wondering if subjective mood scores would be equal for equal DAT blockade in ritalin vs Bupropion. More over I am wondering why ritalin doesn't have the same seziure risk as Bupropion?
Nice; can you do a AED series, like you did with the antidepressants. I like your input on medicines; for example low dose quetiapine is basically a glorified antihistamine.
Does Wellbutrin feel at all like adderall??? I just came off adderrall due to to horrible side effects…too much anxiety, sweating, sleeping, and physical tension I just couldn’t handle anymore….after taking for 10 years. My anxiety is so much better off adderrall but all other symptoms like lethargy and depression are back full force. I’m worried that Wellbutrin will cause similar side effects and increased anxiety. Should I be??
When they released the bupropion/DXM formulation it helped solidify my combination using another SERT compound with far less side effects, 450mg 24hr release + Chlorphenamine 4mg x 3/4 a day, also 13:37 did you screenshot wikipedia? Really hope you never used wikipedia as a source of information within your video, you would lose marks in the test (thumbs down).
Yeah. Leaving the video now, it’s been about 1.5 minutes. I already know I can’t finish listening to you, sorry. Way to click bait. Boring is an understatement.
Please just don't stop.
We (psychiatrists) really need your videos
Not stopping, just starting
Really good videos. Appreciate your service to our education!
🫡
man i also always thought it was buproprion i'm so glad i'm not alone
As a clinical research coordinator loved this break down
Much appreciated!
Thank you SO much for that info on vortioxetine + bupropion! I’ve been looking everywhere for data on combining them (given their interaction) and now I know the suggested max of vort is 10mg in combo. Can you PLEASE cover Vortioxetine in a stand-alone video? It hits so many receptors and it’s so interesting.
It will certainly be a while, but will hopefully eventually get to it
Okay with the Jung deep end joke I had to log in and say:
good channel
good sense of humor
I loved psychopharm (basic, wikipedia) when I was in my late teens and doing drugs, and now I'm in my late 20's trying to find a way to not kms using a lot of the same knowledge and the help of my psychiatrist.
Thank you
Much appreciated! I’m almost there already…
My doctor said that, Wellbutrin inhibits more dopamine than noradrenaline. He said actually it's very week noradrenaline inhibitor. Instead of noradrenaline it works on dopamine. This is what my doctor said
As far s i know its the other was around. It inhibits more Norepinephrine ans lesss Dopamie. Thats why the D is on second place, while the N is first NDRI.
@madlenj.4644 yes it also has an active metabolite that is way more selective for norepinephrine over dopamine
Yeah your doctor definitely got it backwards.
@madlenj.4644 hydroxybupropion affects norepinephrine even more than the parent drug aka bupropion
Amazing video!!! And youre a stud muffin
i wish he could be my psychiatrist
thank you, I'm tired of just getting ndri when I try to find out whats its doing. At least this video had some more in depth information
Thanks!
Thanks! Simply said..
Sorry for grammar errors, i am from Europe.
In my country we still do not have so many variations of the drug as bupoprion.., actualy we have only wellbutrin. For now ...
Thanks for all information and education.
Most important is what U say at the end of the video. For me, at least...
Thanx and b.ok
How common is balding as a side effect? I see it online but doctor and others never mentioned it.
Great video! Made me laugh a few times!
Thanks!
Thanks for the easy break down. ❤
You are the most precious psychiatrist.
(❁´◡`❁)
Flu symptoms sore throat, tremors brain fog derealization that's what I felt muscle aches too
Going through this right now
In following on from the moa diatribe, if you look at the effect of antiseziure drugs as mood stablisers, is it then assuming wrong that an ndri with seziure risk is contraindicated for bipolar mania 🤔
Also I saw somewhere that Bupropion increases plasma levels of reboxetine multiple fold but it wasn't the best source and you won't find it in the literature. Make of that what you will but worth putting out there.
Ritalin isn't used as antidepressant anymore. I wondering if subjective mood scores would be equal for equal DAT blockade in ritalin vs Bupropion. More over I am wondering why ritalin doesn't have the same seziure risk as Bupropion?
Howdy boss. Will I be blessed to hear you talk about Zuranolone in a future video? Cheers :)
Nice; can you do a AED series, like you did with the antidepressants. I like your input on medicines; for example low dose quetiapine is basically a glorified antihistamine.
Maybe one day in the very far future but neurology is not my specialty so will probably stick to the psychiatric component of things
I love you already! Your great!
Excellent content. Thank you
I just realized Bupropion doesn’t have an “r” about two days ago and I’ve probably been on it for 20 yrs 😅. MDD ✅
Is there a benefit in taking more than 300 mg in terms of dopamine and focus? Such as the max dose 450 mg
*Money tree playing* yep this is gonna be a good Psych video
That's just how I feel
I like your staccato speech pattern
Does Wellbutrin feel at all like adderall???
I just came off adderrall due to to horrible side effects…too much anxiety, sweating, sleeping, and physical tension I just couldn’t handle anymore….after taking for 10 years. My anxiety is so much better off adderrall but all other symptoms like lethargy and depression are back full force.
I’m worried that Wellbutrin will cause similar side effects and increased anxiety.
Should I be??
the guy that smells like cabbage on the subway told me its pronounced Buproprion..so we had it right all along
And now I smell like cabbage
Dig this video. Thank you!
Much appreciated!
Since you didn't list spongiform degeneration as a side effect, you know it's bupropion and not "buproprion"! Thank you for another awesome vid!
source?
@@plockacherrys5765 It's a joke. Prion = causative agent of spongiform dementia
😂 this one took me a sec
@@PsychoFarm Can modafinil improve visual memory?
I thought it was 'bupropRion' too. New mandela effect!
Back 50 years ago, we just called these guy’s mamas boys. Now we have all these scientists involved and plenty of medications..
Thanks for this!
You are welcome!
Love your videos!! 😁🔥
I love your video's hehe
Non boring....u sound comatose!!!!! Tu for the info😮😮😮😮
All I have on this drug is insomnia and anxiety. I hate it so far.
you got a linkedin?
Pronounced: Karl Yuung not young.
I still say "Buproprion" to this day lol
I literally learned today propanolol is not propanolol; it's propranolol. Subtracting "r"s is just as bad as adding them.
@@kenhaze5230 Yeah I was calling it that for years. Also "sertaline".
And "Risperidal"
Me too Shane, me too
Made me gain weight i think i am the only one ha ha. Still take it as it has helped me.
Your videos are great but you should get a better mic.
Still Love them though
Audio on next vid will be better I pinky promise
"con-tra-vay" lol is it intentional at this point
One never knows
New subbie here.
Much appreciated!
Madr me feel horrible
You look exactly like your voice
Interesting 🤓
When they released the bupropion/DXM formulation it helped solidify my combination using another SERT compound with far less side effects, 450mg 24hr release + Chlorphenamine 4mg x 3/4 a day, also 13:37 did you screenshot wikipedia? Really hope you never used wikipedia as a source of information within your video, you would lose marks in the test (thumbs down).
youre not a dr? wiki has references. ive used it
Yeah. Leaving the video now, it’s been about 1.5 minutes. I already know I can’t finish listening to you, sorry. Way to click bait. Boring is an understatement.
Way too mumbled. Learn to pronounce the names. Very unreliable information if the presenter can’t even speak clearly.
Decontinuation syndrome lol aka addicting
You sound very unsure about what you are talking about. Sorry. I had to say it.
This is actually the most boring…
☺️ Thanks for taking the time to comment
Ur so funny😭
I for some reason, thought this channel was mainly about drug pharmacokinetics, pharmacodynamics lol