Acute Kidney Injury (AKI) | Etiology, Pathophysiology, Clinical Features, Diagnosis, Treatment

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  • Опубліковано 13 чер 2024
  • Official Ninja Nerd Website: ninjanerd.org
    You can find the NOTES and ILLUSTRATIONS for this lecture on our website at:
    www.ninjanerd.org/lecture/acu...
    Ninja Nerds!
    In this lecture Professor Zach Murphy will be presenting on Acute Kidney Injury (AKI). During this lecture we will be starting with a discussion on the causes of an AKI. This will include the pre-renal, intra-renal, and post-renal causes. We will then transition into the pathophysiology and most common clinical features associated in patients with an AKI. We will then conclude this lecture with the diagnosis and treatment of an AKI. We hope you enjoy this lecture and be sure to support us below!
    Table of Contents:
    0:00 Lab
    0:08 AKI Introduction
    0:29 Causes of AKI: Pre-renal, intra-renal, and post-renal
    45:30 Pathophysiology and Clinical Features of AKI
    1:20:27 Diagnosis of AKI
    1:34:46 Treatment of AKI: Pre-renal, intra-renal, and post-renal
    1:49:03 Comment, Like, SUBSCRIBE!
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    #ninjanerd #AKI #AcuteKidneyInjury

КОМЕНТАРІ • 417

  • @trunghieu5420
    @trunghieu5420 28 днів тому +15

    Whole chapter of AKI is explained in a video instead of a 10-hour lecture where the professors simply read from the slides. You are the best teacher ever. Thank you for your professionalism and enthusiasm !

    • @dannaca
      @dannaca 28 днів тому

      INDEED!! 👏😤

  • @jaiabad1306
    @jaiabad1306 Рік тому +138

    Our college tuition should be going to these amazing people. I learn more from them than I'll ever do from all my college professors. He explains all of these concepts so well, making it SO easy for us to understand. Big thanks to you Mr. Ninja Nerd!

    • @irame5701
      @irame5701 3 місяці тому +1

      Totally agree. I don't know what I pay for at the college.

  • @mashhoodsiddiqui6274
    @mashhoodsiddiqui6274 2 роки тому +145

    I had my neurology exam today and your words were literally echoing in my mind like the components of limbic system and various nuclei of hypothalamus and their functions... you person are the saviour of my grades. May God bless you. Lots of love from Pakistan!!!!

  • @paulastafford1642
    @paulastafford1642 Рік тому +13

    Excellent. Thank you so much. My sister just died September 12 2022 from ATN-AKI confirmed on biopsy. Was in metabolic acidosis never showed signs of volume overload instead was dehydrated 2 days after discharge from hospital. Labs and BP were improving prior to discharge so I was told they didn't feel the need for dialysis. I still think a temporary course of dialysis may have saved her life. She had a Hgb of 8 at discharge, creatinine and BUN were only slightly elevated and K+ was 5.2. She had labs drawn the morning b4 she died and was not notified of any abn, but at the time of blood drawn was told she was dehydrated bc they had a hard time getting blood. I noticed watery loose stools in her toilet the night she died. She'd had a short run of V'tach in the hospital and chronic A-fib x 2 years. She called 911 c/o SOB and they found her face down in her apt and unresponsive. This video helped me a lot. I still believe dialysis should have been tried.

  • @HockeyGuy_in_STL
    @HockeyGuy_in_STL 2 роки тому +133

    Nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently associated with AIN. I took care of a teenage girl in the ER who took ibuprofen for migraine daily for 3 weeks. After H&P and labs, I diagnosed her clinically with AIN and she was admitted to peds. Later that week, a renal biopsy was performed and confirmed AIN. So, be careful with ibuprofen!

    • @ahealingplace7350
      @ahealingplace7350 Рік тому

      Thank you, this is helpful

    • @echase416
      @echase416 Рік тому +3

      NSAIDs are serious medications. I cringe when I hear the phrase ‘take ibuprofen’ mentioned so casually… 💔

    • @shaneoneil894
      @shaneoneil894 Рік тому

      NSAIDS are poison. Jacks up everything and makes almost all chronic diseases worse. I don’t understand why it is otc .

    • @erencihan1103
      @erencihan1103 Рік тому

      NSAID These drugs disrupt renal autoregulation. Cutoffvalie60mmHg

    • @anzlaiqbalmuhammediqbal27
      @anzlaiqbalmuhammediqbal27 Рік тому +1

      What about flurbiprofen

  • @anthonymorici
    @anthonymorici 11 місяців тому +14

    I’m a 48 year old man just diagnosed with renal kidney failure and am deep diving in to my own journey through you! Thank you for providing intelligence and masterful communication! I am understanding what my doctors are attempting to communicate. Thank you, Anthony

  • @yahyeabdi4774
    @yahyeabdi4774 11 місяців тому +4

    Why is this guy such legend that every time I look for a topic I see a one hour video of ninja nerd , exactly what I needed, u son of a gun

  • @zadhi1290
    @zadhi1290 2 роки тому +109

    Ok, Mr. Nerd Ninja I would like to say thanks. I am an IMG working as a PA in a hospital with many interns and this concept and approach to the kidney is by far the best in the game. I will be sending this to everyone I know and modifying my Step study to include your lectures in the subject that I am weak in. It is one thing to understand it in paper but your detailed info make these concept that look hard to manage easy to understand. It is safe to say that you have gone above and beyond with this AKI lecture.

  • @vrushitarora7760
    @vrushitarora7760 2 роки тому +31

    Please even continue with the Microbiology series. No one explains things better than you.. need more of those.

  • @nurula1783
    @nurula1783 Рік тому +3

    man what an absolute legend. been watching for years, endlessly grateful

  • @accountname7982
    @accountname7982 2 роки тому +29

    I just wanna say thankyou for always explaining the basics and then covering the concept. Your channel is truly a gift to the medical community. You describe everything related to the topic, never leave even the smallest things.. that's what i love about you. Much love, keep up the good work. May your channel grow more and more.

  • @saumyas4114
    @saumyas4114 2 роки тому +5

    THERE ARE NO WORDS TO EXPRESS HOW MUCH I LOVE YOU GUYS !

  • @fghhdfg4719
    @fghhdfg4719 2 роки тому +7

    No one can explain this topic more clearly than this
    Amazing thank you

  • @connorhill9047
    @connorhill9047 2 роки тому +22

    I’m a nursing student who loves all of your content. I am someone who needs to know how things are connected, and you do a great job of providing clear visuals and descriptions.
    I just finished your lecture in CKD. I knew I wanted to do AKI next, and there it was in my suggested videos. The only words I have for you: thank you!

  • @malakds400
    @malakds400 Рік тому +32

    Seeing such a hardworking person & the happiness you deliver in every course you share is priceless
    God bless you ; keep it up bro❤️ May Allah show you the right path..Ameen✨️❤️❤️

  • @sakthipriyakurmapu9383
    @sakthipriyakurmapu9383 8 днів тому

    Finally a video on the actual pathophys! Thank You!

  • @andreafigueroa4337
    @andreafigueroa4337 11 місяців тому +4

    This is usually a topic that I despise studying because I struggle so much differentiating the casues of AKI, but I always come back to your videos. Thank you so much for your passion in explaining and making it easy for us to understand

  • @abp-jk7tr
    @abp-jk7tr Рік тому +3

    This man is so good at explaining things and he is so passionate- these are the best videos!

  • @trlanhuseyn741
    @trlanhuseyn741 2 роки тому +31

    Zack, please make lectures about Histology. Appreciate it beforehand.

  • @ilooovedrugs
    @ilooovedrugs 2 роки тому +4

    You're videos are amazing!! thank you for doing this. I'm a registered vet tech and am brushing up on everything and you're videos are so informative and easy to follow!

  • @kingssem1583
    @kingssem1583 2 роки тому +5

    Incredible lecture sir 🙌🏿✊🏿,there is none on the internet better than this .thank You very much!!!!

  • @NickinNashville
    @NickinNashville 2 роки тому +7

    omgosh im so stoked on these videos. You are truly a gifted teacher. I work at University and this blows other classes out of the water, even using the phrase "peeing outta your butt"....

  • @belfiorebianco
    @belfiorebianco 2 роки тому +7

    GOAT, man such thorough detailed lessons. I never understood some complications or side effects, but the way you explain it I think I will not forget. Thank you very much to you and your team.

  • @JorgeMFilho-bs8cb
    @JorgeMFilho-bs8cb 2 роки тому +3

    Ninja nerd you're a jewel in UA-cam. Thanks for your excellent educational work.

  • @JoeElFrancesOficial
    @JoeElFrancesOficial 2 роки тому +4

    Incredible piece of work and beautiful summary, thank you

  • @mcserna650
    @mcserna650 Рік тому +1

    You are the best! Please don't stop doing this amazing job, you were born for it. As an IMG getting ready to take the USMLE you've helped me so much!!! Thank you Dr. Zach

  • @summermaharlika9416
    @summermaharlika9416 2 роки тому +6

    Oh My God. I needed this lecture so much!! I have a report for AKI and this will help me a lot. Thank you so much!! I love you ninja nerd!! ❤️

  • @violetterobinson6542
    @violetterobinson6542 Рік тому +2

    Dude this video is the bomb. I’m going to ace my nursing exam!

  • @grohithraj2733
    @grohithraj2733 2 роки тому +5

    Really excited for the nephrology videos!
    Thanks for all these amazing lectures ❤️

  • @michalcsurilla4485
    @michalcsurilla4485 Годину тому

    Most people on youtube makes 10-20 min videos on this topic… this guy makes almoust 2 h long video 😂. Love this , great video👌👊.

  • @may_mohammad
    @may_mohammad Рік тому +1

    شكرا لكم على هذا الإتْقان

  • @jeanabraham7742
    @jeanabraham7742 2 роки тому +2

    I love the way you say," I am glad you asked" 😊..Big thanks to Ninja Nerds from NZ.

  • @sidneylopez6395
    @sidneylopez6395 2 роки тому +3

    Thank you bro, you teach pathophys in a clear and understandable way

  • @Kate-yi1bv
    @Kate-yi1bv 2 роки тому +3

    Unreal how great these videos are. Thank you!!

  • @sedative87
    @sedative87 2 роки тому +3

    I really appreciate this kind of lecture. It helped me a lot

  • @marcellaryan-coker2832
    @marcellaryan-coker2832 2 роки тому +8

    You are an amazing teacher! Thank you for doing these videos! Can you please please do a video on fluids and electrolytes pathophysiology? 🙈Some ninja nerds will be so very grateful for it😃

  • @nemonihil2952
    @nemonihil2952 2 роки тому +2

    Thanks a lot. Extremely clear and helpful material!

  • @lindsaybarnard6627
    @lindsaybarnard6627 6 місяців тому +1

    Both YOU and the kidneys are equally amazing!!

  • @isabellalavagnino9640
    @isabellalavagnino9640 2 роки тому +3

    You're something else, thank you for all the amazing videos!!

  • @maarrr22
    @maarrr22 Рік тому

    I can't stress enough on how many times ninjanerd has saved my life !!!

  • @noumanshahzad8720
    @noumanshahzad8720 2 роки тому +3

    I really love how you explain all the stuff ♡

  • @ghazalnaz7454
    @ghazalnaz7454 2 роки тому +6

    Thank u soo much sir, urr lectures r Allah's gift for me, my exams r coming ahead, nd im piled up with medicine, surgery, paeds gynae obs😑 and ur lectures specially this medicine series is really helping me out, keep the good work 😇

  • @nanadarkoampem
    @nanadarkoampem 6 місяців тому

    I learn a lot from Ninja Nerd's lectures. His explanations are easily understood and absorbed.

  • @rameezsuleman8784
    @rameezsuleman8784 2 роки тому +2

    Very much clearly explained I am very thankful of your being a my teacher I respect you a lot thanks for sharing me this wonderful knowledge

  • @luciaperez1832
    @luciaperez1832 2 роки тому +2

    As always guys, we appreciate your work a lot!

  • @laurasookhai7802
    @laurasookhai7802 Рік тому +1

    Thank you so much...nursing student here, I wish professors could break it down like you do but unfortunately that's not the case, thank god for you! 🙏

  • @stevehb777
    @stevehb777 Рік тому

    Long videos but full of knowledge. You KNOW this guy knows his shit because he breaks it down to the most simple level.

  • @abytebit
    @abytebit 2 роки тому +3

    This is something what I've looking for... THX MAN!

  • @adfd9607
    @adfd9607 2 роки тому +1

    Thaaaank yoooou, I've looked for it in the renal playlist it's finally here thank you

  • @irame5701
    @irame5701 3 місяці тому

    Love this guy: innocent and sincere in expressions and powerful with his knowledge! 👍❤️

  • @2006evita
    @2006evita Рік тому +1

    I am learning so much from you. You are a great teacher. You make it entertaining and exciting. Thanks a lot

  • @ashm003
    @ashm003 2 роки тому +4

    Thank you for another great lecture!

  • @MarkBennett007
    @MarkBennett007 2 роки тому

    As a layman…..this is over my head…… but listen and realise what a deep subject it is.
    Aiming to improve via diet…….can’t afford diagnosis and dietician based on labs.
    Wishing you all that’s good….you deserve it.
    Thank you.

  • @frankmaggio4328
    @frankmaggio4328 2 роки тому +6

    Thank you for making this video. As an ER Nurse we see, we treat, we either d/c or admit. We leave it up the NP,PA,MD to figure out what's going on with the patient. After a while you start to ask deeper questions as to why this was ordered and why that was ordered. Thanks for explaining AKI. Now I know why the U/S are ordered after the chemistry and u/a comes back. Now everything is CT scans but I always wondered why the U/S order but was too busy to ask.

  • @ariahunonso6981
    @ariahunonso6981 Місяць тому

    You are an excellent teacher! Thank you for all the work that you do 👏👏

  • @maddiefreier-engle1497
    @maddiefreier-engle1497 2 місяці тому

    One of a kind teacher. So grateful.

  • @monishshivamonishshiva5392
    @monishshivamonishshiva5392 2 роки тому +2

    Mesmerized 😊, Amazing 🙏🏻, this class very much useful ...

  • @selenaserane2623
    @selenaserane2623 Рік тому

    Second time i repeat that from start to finish, i don't get bored, everytime u say makes sense right! I say deep down ofc it does with a big joy, thx a lot

  • @billionairetrillionaire2356
    @billionairetrillionaire2356 Рік тому +1

    Wow wow you are amazing, a gift from heaven indeed
    We need pay our fees to support u to rather make more videos for us

  • @DrsundasMD
    @DrsundasMD 8 місяців тому

    N i bet no person could work more harder than prof zach Murphy ❤

  • @shaneoneil894
    @shaneoneil894 Рік тому +28

    I pay thousands a year in school fees and I get more value from your UA-cam lectures. Thank you. I’ve gotten a bunch of As due to your efforts.

  • @hibakamran3554
    @hibakamran3554 2 роки тому +1

    That's so gripping 👌🤗thanks Dr. Zach

  • @Rayan.F
    @Rayan.F Рік тому

    What an absolute beast. Thank you very much for these videos they are really helpful for my internal exam👍

  • @squirrel5811
    @squirrel5811 2 роки тому +2

    Blue clues for medical lectures. This stuff is amazing.

  • @rayyaalghazali5349
    @rayyaalghazali5349 2 роки тому +1

    Thank you from the bottom of my heart

  • @mohammedjama8067
    @mohammedjama8067 2 роки тому +2

    Thank you very much from Ethiopia, really i love your teaching techniques, and thanks.

  • @mariama.sgodhelpme2264
    @mariama.sgodhelpme2264 10 місяців тому

    After getting disappointed from nephrology , here I am to strat again all is due to this great explanation , In whole my life I didn't find someone explaining like this , God bless you sir , all love to you , respect and good luck always your easy detailed words still in my brain , i can't forget ❤❤

  • @ObnoxiousOtter8
    @ObnoxiousOtter8 11 місяців тому

    I will now forever associate AKI not by the aetiology of the reduced eGFR - no, never again - but a by new criteria for a new age: whether tubular cells are all jacked up or not.
    We love you, Ninja Nerd Team. Thank you from the bottom of our hearts, may God bless you.

  • @prudenceikejiofor8178
    @prudenceikejiofor8178 2 роки тому +3

    Thank you very much for these priceless contents. Pls, which texts do you use for studies before these lectures?

  • @amineahsengeldi3071
    @amineahsengeldi3071 4 місяці тому

    Thank you so much that finally I understand this subject. Thank you and to your team for your passion and effort :))

  • @joseibarra4485
    @joseibarra4485 Рік тому +1

    Thank you for your lectures! Life saver!

  • @giovannotecconecco6269
    @giovannotecconecco6269 2 роки тому +4

    content is awesome, just a little note, at around min. 7.46 when he describes nephrotic syndrome he is describing characteristics of nephritic syndrome (hematuria, hypertension and lipiduria)

  • @ivanakurdi6139
    @ivanakurdi6139 Рік тому +2

    As always you are the hero man❤ and you’re always saving our life😢❤

  • @nadasalah4343
    @nadasalah4343 Місяць тому

    From Egypt thank you so much for this amazing lecture

  • @raghavparanjape1551
    @raghavparanjape1551 2 роки тому +2

    Zach sir I'd just like to request that it would be cooler if you could divide one huge video into two or three parts, like your previous older content, so that it becomes easier for us. Otherwise, i just love you and ninjanerd!!

  • @Masmaskias
    @Masmaskias 2 роки тому +7

    I am JUST now seeing this after I took my exam of off this subject 😭😭 I love how you explain the diseases. But thanks for this video! Will be helpful for my final ❤️

    • @rameezsuleman8784
      @rameezsuleman8784 2 роки тому +2

      Knowledge is better then a piece of high marks degree

    • @apostolismoschopoulos1876
      @apostolismoschopoulos1876 2 роки тому +1

      @@rameezsuleman8784 unfortunately society wants you to acquire that piece of degree

    • @rameezsuleman8784
      @rameezsuleman8784 2 роки тому

      @@apostolismoschopoulos1876 knowledge is better then a piece of degree .yes I know the degree is also must be in your hand but if you haven't knowledge then fire this degree .

    • @apostolismoschopoulos1876
      @apostolismoschopoulos1876 2 роки тому +1

      @@rameezsuleman8784 unfortunately I cannot relate to this argument. I have seen people with less knowledge get better position and social status just because of appearance. We are not directly rewarded by our knowledge but more like by the way we present that knowledge to others.

    • @dennisarzubiaga2833
      @dennisarzubiaga2833 2 роки тому

      Asomeness Alondra 🤪

  • @compilation8104
    @compilation8104 7 місяців тому

    how i regret that i didnt find u earlier still im so grateful. hope to comeback after acing my exam to thank u

  • @louiskanini7888
    @louiskanini7888 Рік тому +1

    I like it when u say "I don't want u guys to spend too much time thinking about it" , until I hv a patient with the same condition or i get asked about it during ward rounds 😭😭... Otherwise, you're @ explaining clearly. Thank you!

  • @karengallie9783
    @karengallie9783 3 місяці тому

    These lectures are so good. I have learnt so much thank you. 🎉

  • @m.e.2286
    @m.e.2286 2 роки тому +2

    PROF ZACH, P.A., G.O.A.T. 🔥🏆💪🏽🌟
    Much love ❤️🙏🏼

  • @ceciliacheptoo4945
    @ceciliacheptoo4945 2 роки тому

    Ua videos are exhaustive and soo helpful..i search for your videos in every topic of internal medicine I read...thanks🤗🤗

  • @rudolfdiesel7.3version31
    @rudolfdiesel7.3version31 Рік тому

    Wow! I am not a medical student and I can follow along. Thanks so much, helped on this end.

  • @Argos534
    @Argos534 2 роки тому

    Greetings from mexico this is one of the best yt medical channel i’ve ever seen,,

  • @MeddymaticsDrSwatiPandey
    @MeddymaticsDrSwatiPandey 8 місяців тому

    I love the way you explain things so easily.....❤️ Keep it up... spread knowledge

  • @tamipock3578
    @tamipock3578 2 роки тому +3

    Thank you for all the videos. I would love to see you do a video about pulmonary hypertension. I have this due to a congenital heart defect.

  • @hannateodrosgirmatsion9155
    @hannateodrosgirmatsion9155 2 роки тому

    I can't stop watching your videos even I am level one nursing student thanks!

  • @chrystalselous1511
    @chrystalselous1511 7 місяців тому

    I love this video, so clearly explained, thanks Dr

  • @longjohn2726
    @longjohn2726 Рік тому +1

    Amazing you helped me a lot. You are the best!!!!

  • @BunleangKors
    @BunleangKors Рік тому

    I like to learn from your teaching so much. Thank you for your knowledge's sharing.

  • @humbertohenriquez1722
    @humbertohenriquez1722 2 роки тому

    Thank you for making things clear for dummies

  • @bozo4188
    @bozo4188 Рік тому

    Omg i really need your energy and your brain for my exams

  • @nuttyhill3218
    @nuttyhill3218 Рік тому

    You made me love this topic💚thank you

  • @MrKhannasahil
    @MrKhannasahil 2 роки тому +1

    Thanks for the acceptance of topic suggestion of arf and causes 👍🙏

  • @federicaburatti4267
    @federicaburatti4267 2 роки тому +2

    Zac we are waiting for Acute coronary syndrome 🙏🙏 we need this lecture!

  • @anweedebta7781
    @anweedebta7781 2 роки тому +2

    Thank you so much.. 🙂🙂 Finally understood physiology 🙃

  • @miraq3261
    @miraq3261 8 місяців тому

    شنو هالابداع رهيب وربي 🔥🔥🔥

  • @eduardat3449
    @eduardat3449 2 роки тому +1

    Thank you, you are saving me!

  • @omarelkholy8667
    @omarelkholy8667 2 роки тому +1

    Amazing. This is how medicine should be taught

  • @surreyhub7108
    @surreyhub7108 2 роки тому +1

    Wow thank you that was so informative you are very talented and know your stuff.

  • @abdihome9847
    @abdihome9847 Рік тому

    Thank u very much u make our life simple by ur detailed explanation....