This is my favourite supplement ever. After years of severe anxiety and trauma my cortisol levels were out of control and even effecting my cycle and sleep cycles. This is the only supplement which made a large difference for me. Thank you for your detailed video on this wonderful nootropic. 😊
@@hkondabeatz8203 You can get 100 mg PS in each dose of Mind Lab Pro (bit.ly/3lh3w8a). If you want it in a standalone supplement look for one that uses Sharp PS Green. Like this one: amzn.to/2H3KUJh
Omg this is my second day taking this. I actually didn't expect anything. What I have gotten is EXTREME FOCUS and sleep... My mind is so active I can never relax and sleep on average 4 hrs a night which is not good sleep. I took Gabapentin for sleep a few nights and the next day I felt mentally slow. I will never take that drug again. When I say phosphatidylserine has made a dramatic impact. It's like if u had 8 shots. U know u aren't drunk because it's in your mind, u are drunk because you have no other reaction choice. Well the focus in this supplement is shocking. I know to reach optimal or maximal focus from this phosphatidylserine it may take weeks. I am excited to see how this goes. And the sleep is crazy, we are talking complete calmness. My mind isn't racing. Anyways. This is absolutely amazing. Thanks doc.
Update: I am still taking this supplement. It's incredible. I have never felt so relaxed yet sharp. Similar relaxation to marijuana with no high... Which is amazing.
@@denny8111 Nature's Purest brand. Last night I took it before I went to bed for the first time. When I take it in the mornings everything goes really well but I get too tired at around 8:00 at night. Which that's way too early I want to hang out with my wife. so I took it last night I slept like a baby I feel really good right now so hopefully I'm not extremely tired at 8:00 at night again but we'll see I'll keep you guys posted!
I have MS , most of my problemes are with the concentration, memory and brain fog. I was suprised at how it helped. Might become a neuroscientist now 🤣. Thank you so much for taking the time to help people wit your videos. 🙏🏼🙏🏼
I came back to thank you for this vídeo. My 9yo is finally controlling his anger and his learning abilities have tremendously increased. He is finally a happy kid! I'm giving him 1g of omega 3 and 300mg of phosphatidylserine on breakfast.
I stumbled across your channel by fluke today. It is a wonderful service you pay to humanity with this UA-cam channel. Thank You so much! it is very informative, you go into great detail and you are also easy to listen to and follow. Bless You!!!
I just saw your video because I have been searching for this name for a while now. I have yet to use this medication or do a full study on it, but the information you provided appears to be very interesting. I also noticed almost immediately that there are comments below that appear to me to be negative remarks. One person stood out, and I will click on your reply as soon as I finish typing. lol, but I do believe in this medication and will have to consult with my doctor first before taking it, but I agree with that individual. :) God Bless us all
Jorge, Phosphatidylserine is not a medication. But a natural lipid that occurs in your brain and is makes up each brain cell membrane which is a combination of Phosphatidylserine, Phosphatidylcholine and DHA (Omega-3).
This helps with my anxiety I have gone up 2 ,3 hundred And now debating on a 1000 mg. Because it is just incredible for my anxiety. And he says it's non toxic awesome
Your body only needs max. 300 mg per day. This supplement is fat soluble so if you overdose it will eventually build up to toxic levels and work against you. Always, always follow dosage recommendations because they are based on clinical studies as well as practical everyday user experience. More is never, ever better with nootropics.
I’ve been taking Phosphatidylserine for years now. Recently I was diagnosed with a Severe Fatty Liver. I’ve been taking 500mg of Choline&Inositol to get rid of the fatty liver. I’m also eating Keto and have lost 115lbs. I had a recent ultrasound performed and now my liver disease is a “Mild Fatty Liver”. I decided to start supplementation with Choline to fully rid myself of Fatty Liver. Do you see, or have you heard of any adverse interactions with Choline and Phosphatidylserine?
This is a little complicated so I'm going to let Oregon State University provide some clarity. Go to this section: lpi.oregonstate.edu/mic/other-nutrients/choline#deficiency. And they explain the causes of fatty liver disease. There are several 'causes' mentioned in that section. See which one may apply to you and possible remedies.
Whenever I take something that lowers cortisol (seems like every nootropic...) I get super unmotivated to do stuff. I spent weeks pushing stuff off when I was taking ashwagandha. Hopefully this doesn't do that
I’ve noticed increased motivation, but I also had slightly elevated cortisol. You might do better with something like adrenal cortex or dessicated adrenal.
You talked about Serinaid and Sharp PS green phosphatidylserine In this video but never talked about "Brainew'phosphatidylserine but I don't think it was out doing the time of this video! So I was wondering if you could do some research on it and explain it to us.Thanks for enlightening us on a great variety of Nootropivs!
Thank you for everything you post, very helpful and i always learn something. I do have a question? Is it good to take a little dose of everything? (Alpha GPC, Uridine, Centrophenoxine etc? I use it morning, pre workout and at night)
JA, "a little dose" is not likely to help much. But you can use them all. Just not sure how much benefit you'll get from Centrophenoxine if you're using Alpha GPC, Uridine and PS.
Colin, it should start working within 30 mins. of taking it but because of the nature of this phospholipid you'll get the most benefit using 100 mg 3-times per day. And start to experience the real benefit in a couple of weeks of using it.
@@NootropicsExpert thank you I’ll def do that! Want to start out slow like 1 a day to get used to it, then start taking 300mg a day from there on out! Thanks for the info.
Thank you for this video. Excellent info that I will use in purchasing my supplements. Is there a supplement that directly or indirectly increases BDNF?
Dwight, I haven't gotten around to doing the video yet but will soon. Here are 13 nootropics that boost BDNF: nootropicsexpert.com/13-nootropics-to-boost-bdnf/
I mainly want to take PS 100 to lower my cortisol levels to then get better more restful and deeper sleep so should i start out with only PS 100 or the mind lab pro stack ?
Jonathan , you need 100 mg PS 3-times per day. So if you take your Mind Lab Pro in the morning then take another 100 mg PS at noon and another 100 mg around 4 PM. It's fat-soluble so make sure you take it with a healthy fat of some kind.
Hi there, I really need your help! I'm 25, male, workout strenuously 6 days a week. I feel my brain is shutting down, I've tried L theanine, ashwaghanda, sulforaphane, PQQ with coq10. They don't work. I've also tried Lions mane, and yes it did work and I felt good at 1000mg , but my asthma flared up slightly, and also I heard if you come off it, the good effects go away. I want something stable and robust. I feel i get stressed easy, energy feels low even after eating, can't concentrate properly, memory is quite poor, brain just feels inflamed and burnt out. My question is: I've done tonnes of research and these two keep popping up: Phosphatidylserine and CDP-Choline. Which one would be more effective? I know both would be good but I want to keep it simple and just use as little supplementation as possible. Thank you!
Sean, you have your first clue on what's wrong. If Lion's Mane worked for you it may be because you are low in brain-derived neurotrophic factor (BDNF) or nerve growth factor (NGF). That is Lion's Mane claim to fame in the nootropic world. It's one of the best ways to boost BDNF and NGF. Please see my post that includes 13 nootropics to boost BDNF: nootropicsexpert.com/13-nootropics-to-boost-bdnf/ Phosphatidylserine (PS) is considered by some to be the best nootropic available. And it's worth trying. See my video on PS on this channel. It helps Nerve Growth Factor and works even better when stacked with a DHA supplement. CDP-Choline is used to increase acetylcholine in your brain. It'll only be beneficial if you are low in acetylcholine. And the only way to find out is try it and see if you feel better. If not, then you know you're not low in acetylcholine.
@@NootropicsExpert thank you ever so much for your detailed reply. I'll give these a go. You are an inspiration and love your work and what you do. Stay healthy! Take care buddy.
You may also wanna try a “less is more” approach to exercise. This is coming from someone who learned the hard way. You can definitely overwork your nervous system via exercise.
Marcela, doctors are not taught this stuff in med school. Their schools are financed by the pharmaceutical companies so all they learn about are drugs. There is no published dose of PS for someone 9 yrs old. But I would think 100 mg should be safe because PS is a natural lipid that participates in maintaining the health of brain cell membranes. Which is critically important no matter what age you are.
Courtney, VitaCholine is a brand name for choline bitartrate which makes a poor nootropic because it does not easily cross the blood-brain barrier. You can certainly use PS with it but you will only be getting the brain benefits from PS.
How long does it take for PS to take notciable effect? Is it immediate? Or would it have to be taken consistently for a couple weeks to have noticable improvements? For my particular desire to use this would be for creativity and mental clarity. Ive heard a lot of good things about PS but what are the studies showing its performance compared to placebo and how many studies strengthen that claim? P.s. (no pun intended) i know ive been harsh in comments before, but you do have good content and i was just picking out things I disagree with) but im asking those questions to really understand Ps and if I should buy it
Hannibal, PS will begin working right away. But the benefits will grow the longer you use it. Think about how phospholipids work in repairing and maintaining cell membranes. As they get healthier the better your brain will work.
So if a cow's brain was to be consumed, how much and how many times a week should it be? I have known as "forgetful" from a younger age. Do other factors involve losing ps earlier than age 20?
Ayesha, the problem is there is no way to measure how much PS there is in cow's brain. And there's not likely enough for nootropic value anyway. Best to use a supplement. PS has been shown to begin declining in your 20's. I don't think it has been tested in kids.
Is Lecithin an ingredient of PS? Or is Lecithin almost the same as PS? If, how many mg of Lecithin do i have to take istead of PS? And what has cholin to do with it? Super intresting!
PS is extracted from lecithin. And it works with DHA and PC to keep brain cell membranes healthy. You brain raids brain cells membranes for choline if you do not have enough available to produce acetylcholine. Which is why it's a good idea to be using Alpha GPC or CDP-Choline. So your brain does not canibalize itself.
I think that larger studies only found small benefits for Phosphatidylserine (PS) related to memory. The effects might go away if you take it for a longer period. Note also that PS from soy is different than PS from bovine. Most studies were done with bovine PS. Further, there are few recent clinical studies, so it seems that researchers have lost their interest in PS. However, maybe it helps a bit.
Michael, I make reference to 13 clinical studies for this video and transcript. And while the science is important, I think more important is *_how it feels when you use PS as a supplement_* . This is what users of the bestselling PS supplements on Amazon had to say about using PS as a supplement: - Boosts energy levels - Improves alertness - Less brain fog - Better memory - Logical thinking improves - Concentration is better - Clarity of thought - Weight loss - Easier to remember names, phone numbers, tasks, etc. - Mood improves - Anti-anxiety - Lowers cortisol - Relieves insomnia - Vivid dreams
Gary, no easy answer to this because it is complicated. There are clinical studies being done measuring PS on the outer layer of cell membranes (PS is part of the inner layer of cell membranes) to determine the presence of cancer. Like this study: pulse.ly/jqv46lhm1u. And they are using PS as a targeted therapy for various kinds of cancers. I have not seen any clinical study suggesting that someone with cancer should avoid supplementing with PS.
Very educational , thank you. Do you recommend 11 years old girl with ADHD and processing problem to take it , if so then how many milligrams. Thank you
Olga, I'm not a doctor so cannot advise you one way or the other. PS would be a good choice however based on my research. If it was my daughter I'd have her using 50 mg per dose.
Olga, look for a patented version using sunflower lecithin like one that uses Sharp PS. I don't think you'll find one with a 50 mg capsule. So you'll need to open the capsule and discard half of the powder.
I just came across this video. I wish I had seen it sooner. I wanted to ask can I give PS to my autistic child? She is 5years old and is non verbal. Also which brand and how much do you recommend I give her?
I have not come across any research showing PS helps with autism. This is a link to my article about nootropics for autism which may help: nootropicsexpert.com/unlocking-the-benefits-of-nootropic-supplements-for-autism/
Hello sir, serine seemed to be more expensive than choline in supplement form here in the market.. is it just ok to opt for choline, since choline can be synthesized as serine? or is it not as effective than taking serine itself? my main purpose is to improve my memory, thank you.
The thing is regular choline has a hard time getting into your brain. The only choline supplements with true nootropic value are Alpha GPC and CDP-Choline (Citicoline).
Praveen, phosphatidylserine is a fat-soluble so must be taken with a healthy fat for it to work. Like a tablespoon of unrefined coconut oil, MCT Oil or Extra Virgin Olive Oil.
Hugh, some consider PS the be the best nootropic we have for cognitive health. But if you're using any stimulant drug for ADHD you'll get much better results with a good ADHD stack which is explained in this video: ua-cam.com/video/S5eKdEZDdBM/v-deo.html
PS is fat soluble and you only need 300 mg per day. So, one cap of that supplement will provide 250 mg that if used consistently and long-term should provide the benefits I mentioned in this video.
Bruno, PS can be in veggie or or regular capsules. But it must be taken with food with some oil or fat in it. Or a tablespoon of unrefined coconut oil or extra virgin olive oil for absorption. Because it is fat-soluble.
my naturopath doctor who I think is just in it for the money.....wants to give me a drip using phosphatidyl choline for sleep but I think he has the wrong amino acid.....it is phosphatidyl serine that helps with sleeps because it lowers cortisol....am I right..????
what do you think of a psych. doctor who wants to give you between 10 to 30 infusions into your vein in your arm of the other phosphatidyl ......isn't that dangerous??? once a week he has some nurse come in and do an inter veinous(spelling) of this amino acid.....he claims it will help me come off a benzo (klonopin)......I think this is a dangerous fad and then he says,"oh, you can take the phosphatidyl serine in tablet form.....how many mgs in tablet form for lowering of cortisol and which company would make the best tablet.
@@dianelindenberger6941 Diane, some use PS infusions as an anti-aging protocol. It's not dangerous. If taken as a supplement it's 100 mg 3-times per day. And look for one that uses Sharp PS Green like this one: amzn.to/3bUb3FC
@@NootropicsExpert but it has many side effects... I have another question I have low blood pressure and I'm taking L tyrosin and 5htp which lowers it even more I've heard this medications is effective or do you recommend other ways that I can increase it?
@@nazigol289 You are not likely using enough Tyrosine. The normal recommended dose if 500 mg 2 or 3-times per day. And 5-HTP is not a great idea anyway. Why are you using it? If it's for sleep a far better choice is 500 mg L-Tryptophan.
Phosphatidylserine is fat-soluble so needs to be taken with a healthy fat for your system to absorb and use it. Otherwise, it will be excreted out of your system unused.
@@NootropicsExpert Thanks for the response. Can you give me an advice when to take L-tryptohan, Phosphatidylserine and L theanine? what is for day and what is for evening?
@@Harvz02 L-Tryptophan about 60 minutes before bed. Lower dose L-Theanine can be used during the day but no more than 100 mg. Higher doses taken at the same time as Tryptophan. And Phosphatidylserine dosage is 100 mg 3-times per day (morning, noon and late afternoon).
Watts, google or search for "Phosphatidylserine: Benefits for Children" and you'll get a doc that shows the list of clinical studies for PS used in teens.
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This is my favourite supplement ever. After years of severe anxiety and trauma my cortisol levels were out of control and even effecting my cycle and sleep cycles. This is the only supplement which made a large difference for me. Thank you for your detailed video on this wonderful nootropic. 😊
How much Mg you take on day? Thank you:)
What brand
@@hkondabeatz8203 You can get 100 mg PS in each dose of Mind Lab Pro (bit.ly/3lh3w8a). If you want it in a standalone supplement look for one that uses Sharp PS Green. Like this one: amzn.to/2H3KUJh
Omg this is my second day taking this. I actually didn't expect anything. What I have gotten is EXTREME FOCUS and sleep... My mind is so active I can never relax and sleep on average 4 hrs a night which is not good sleep. I took Gabapentin for sleep a few nights and the next day I felt mentally slow. I will never take that drug again.
When I say phosphatidylserine has made a dramatic impact. It's like if u had 8 shots. U know u aren't drunk because it's in your mind, u are drunk because you have no other reaction choice. Well the focus in this supplement is shocking. I know to reach optimal or maximal focus from this phosphatidylserine it may take weeks. I am excited to see how this goes. And the sleep is crazy, we are talking complete calmness. My mind isn't racing.
Anyways. This is absolutely amazing. Thanks doc.
What brand do you recommend?
Update: I am still taking this supplement. It's incredible. I have never felt so relaxed yet sharp. Similar relaxation to marijuana with no high... Which is amazing.
@@dmbobby7978 hi what brand do you take?
@@denny8111 Nature's Purest brand. Last night I took it before I went to bed for the first time. When I take it in the mornings everything goes really well but I get too tired at around 8:00 at night. Which that's way too early I want to hang out with my wife. so I took it last night I slept like a baby I feel really good right now so hopefully I'm not extremely tired at 8:00 at night again but we'll see I'll keep you guys posted!
Same. I’m taking 300 mg every night with dinner. My sleep problems are finally improving! It took about a month to start seeing results though.
I have MS , most of my problemes are with the concentration, memory and brain fog.
I was suprised at how it helped. Might become a neuroscientist now 🤣.
Thank you so much for taking the time to help people wit your videos. 🙏🏼🙏🏼
Thanks for reporting in. it's why I make these videos in the first place. Glad they are helping.
do you feel better please ?
I came back to thank you for this vídeo. My 9yo is finally controlling his anger and his learning abilities have tremendously increased. He is finally a happy kid! I'm giving him 1g of omega 3 and 300mg of phosphatidylserine on breakfast.
Thank you Marcela. Happy to hear you are making progress.
Wow I never knew phosphatidylserine was so important and did so many things i will definitely add to my stack
I stumbled across your channel by fluke today. It is a wonderful service you pay to humanity with this UA-cam channel. Thank You so much! it is very informative, you go into great detail and you are also easy to listen to and follow. Bless You!!!
Thank you Mare. Much appreciated.
I just saw your video because I have been searching for this name for a while now. I have yet to use this medication or do a full study on it, but the information you provided appears to be very interesting. I also noticed almost immediately that there are comments below that appear to me to be negative remarks. One person stood out, and I will click on your reply as soon as I finish typing. lol, but I do believe in this medication and will have to consult with my doctor first before taking it, but I agree with that individual. :) God Bless us all
Jorge, Phosphatidylserine is not a medication. But a natural lipid that occurs in your brain and is makes up each brain cell membrane which is a combination of Phosphatidylserine, Phosphatidylcholine and DHA (Omega-3).
This helps with my anxiety I have gone up 2 ,3 hundred And now debating on a 1000 mg. Because it is just incredible for my anxiety. And he says it's non toxic awesome
Your body only needs max. 300 mg per day. This supplement is fat soluble so if you overdose it will eventually build up to toxic levels and work against you. Always, always follow dosage recommendations because they are based on clinical studies as well as practical everyday user experience. More is never, ever better with nootropics.
I’ve been taking Phosphatidylserine for years now. Recently I was diagnosed with a Severe Fatty Liver. I’ve been taking 500mg of Choline&Inositol to get rid of the fatty liver. I’m also eating Keto and have lost 115lbs. I had a recent ultrasound performed and now my liver disease is a “Mild Fatty Liver”. I decided to start supplementation with Choline to fully rid myself of Fatty Liver. Do you see, or have you heard of any adverse interactions with Choline and Phosphatidylserine?
This is a little complicated so I'm going to let Oregon State University provide some clarity. Go to this section: lpi.oregonstate.edu/mic/other-nutrients/choline#deficiency. And they explain the causes of fatty liver disease. There are several 'causes' mentioned in that section. See which one may apply to you and possible remedies.
There’s also phosphatidyl choline.
Whenever I take something that lowers cortisol (seems like every nootropic...) I get super unmotivated to do stuff. I spent weeks pushing stuff off when I was taking ashwagandha. Hopefully this doesn't do that
I’ve noticed increased motivation, but I also had slightly elevated cortisol. You might do better with something like adrenal cortex or dessicated adrenal.
You talked about Serinaid and Sharp PS green phosphatidylserine In this video but never talked about "Brainew'phosphatidylserine but I don't think it was out doing the time of this video! So I was wondering if you could do some research on it and explain it to us.Thanks for enlightening us on a great variety of Nootropivs!
Brainew PS is just a brand name. It is not patented form of Phosphatidylserine like Sharp PS Green or SerinAid.
Very interesting. 🤗
In German it would be even better, but it works with Google translators. 🖥🤓
Thank God for Google Translator because I have enough of a challenge with English.🙂
Thank you for everything you post, very helpful and i always learn something. I do have a question? Is it good to take a little dose of everything? (Alpha GPC, Uridine, Centrophenoxine etc? I use it morning, pre workout and at night)
JA, "a little dose" is not likely to help much. But you can use them all. Just not sure how much benefit you'll get from Centrophenoxine if you're using Alpha GPC, Uridine and PS.
NootropicsExpert thank you. I’m not sure either.
I just bought this so it can hopefully be able to concentrate better at work! I don’t go in until 5pm! When is a good time to take this? Thanks
Colin, it should start working within 30 mins. of taking it but because of the nature of this phospholipid you'll get the most benefit using 100 mg 3-times per day. And start to experience the real benefit in a couple of weeks of using it.
@@NootropicsExpert thank you I’ll def do that! Want to start out slow like 1 a day to get used to it, then start taking 300mg a day from there on out! Thanks for the info.
Thanks!
Welcome!
Thank you for this video. Excellent info that I will use in purchasing my supplements. Is there a supplement that directly or indirectly increases BDNF?
Dwight, I haven't gotten around to doing the video yet but will soon. Here are 13 nootropics that boost BDNF: nootropicsexpert.com/13-nootropics-to-boost-bdnf/
I mainly want to take PS 100 to lower my cortisol levels to then get better more restful and deeper sleep so should i start out with only PS 100 or the mind lab pro stack ?
Jonathan , you need 100 mg PS 3-times per day. So if you take your Mind Lab Pro in the morning then take another 100 mg PS at noon and another 100 mg around 4 PM. It's fat-soluble so make sure you take it with a healthy fat of some kind.
Hi there, I really need your help! I'm 25, male, workout strenuously 6 days a week. I feel my brain is shutting down, I've tried L theanine, ashwaghanda, sulforaphane, PQQ with coq10. They don't work. I've also tried Lions mane, and yes it did work and I felt good at 1000mg , but my asthma flared up slightly, and also I heard if you come off it, the good effects go away. I want something stable and robust. I feel i get stressed easy, energy feels low even after eating, can't concentrate properly, memory is quite poor, brain just feels inflamed and burnt out.
My question is: I've done tonnes of research and these two keep popping up:
Phosphatidylserine and CDP-Choline.
Which one would be more effective? I know both would be good but I want to keep it simple and just use as little supplementation as possible.
Thank you!
Sean, you have your first clue on what's wrong. If Lion's Mane worked for you it may be because you are low in brain-derived neurotrophic factor (BDNF) or nerve growth factor (NGF). That is Lion's Mane claim to fame in the nootropic world. It's one of the best ways to boost BDNF and NGF.
Please see my post that includes 13 nootropics to boost BDNF:
nootropicsexpert.com/13-nootropics-to-boost-bdnf/
Phosphatidylserine (PS) is considered by some to be the best nootropic available. And it's worth trying. See my video on PS on this channel. It helps Nerve Growth Factor and works even better when stacked with a DHA supplement.
CDP-Choline is used to increase acetylcholine in your brain. It'll only be beneficial if you are low in acetylcholine. And the only way to find out is try it and see if you feel better. If not, then you know you're not low in acetylcholine.
@@NootropicsExpert thank you ever so much for your detailed reply. I'll give these a go. You are an inspiration and love your work and what you do. Stay healthy! Take care buddy.
You may also wanna try a “less is more” approach to exercise. This is coming from someone who learned the hard way. You can definitely overwork your nervous system via exercise.
My son suffers from adhd, he's 9. What would be the proper dose for him? Doctos here never heard of phosphatidylserine.
Marcela, doctors are not taught this stuff in med school. Their schools are financed by the pharmaceutical companies so all they learn about are drugs.
There is no published dose of PS for someone 9 yrs old. But I would think 100 mg should be safe because PS is a natural lipid that participates in maintaining the health of brain cell membranes. Which is critically important no matter what age you are.
@@NootropicsExpert thank you ❤️🌹
Can I take PS while taking a choline supplement (VitaCholine)? Not acytylcholine though, or is it the same thing?
Courtney, VitaCholine is a brand name for choline bitartrate which makes a poor nootropic because it does not easily cross the blood-brain barrier. You can certainly use PS with it but you will only be getting the brain benefits from PS.
How long does it take for PS to take notciable effect? Is it immediate? Or would it have to be taken consistently for a couple weeks to have noticable improvements? For my particular desire to use this would be for creativity and mental clarity. Ive heard a lot of good things about PS but what are the studies showing its performance compared to placebo and how many studies strengthen that claim?
P.s. (no pun intended) i know ive been harsh in comments before, but you do have good content and i was just picking out things I disagree with) but im asking those questions to really understand Ps and if I should buy it
Hannibal, PS will begin working right away. But the benefits will grow the longer you use it. Think about how phospholipids work in repairing and maintaining cell membranes. As they get healthier the better your brain will work.
NootropicsExpert awesome! Thank you. Ill give it a try
Hello,i take strattera with Phosphatidylserine
Great combo.
Is taking this in the morning with other stacks and pre workout in a dose of 300 mgs twice a day - thank u.
JA, not sure what you're asking here.
So if a cow's brain was to be consumed, how much and how many times a week should it be? I have known as "forgetful" from a younger age. Do other factors involve losing ps earlier than age 20?
Ayesha, the problem is there is no way to measure how much PS there is in cow's brain. And there's not likely enough for nootropic value anyway. Best to use a supplement.
PS has been shown to begin declining in your 20's. I don't think it has been tested in kids.
Is Lecithin an ingredient of PS?
Or is Lecithin almost the same as PS?
If, how many mg of Lecithin do i have to take istead of PS?
And what has cholin to do with it?
Super intresting!
PS is extracted from lecithin. And it works with DHA and PC to keep brain cell membranes healthy. You brain raids brain cells membranes for choline if you do not have enough available to produce acetylcholine. Which is why it's a good idea to be using Alpha GPC or CDP-Choline. So your brain does not canibalize itself.
I think that larger studies only found small benefits for Phosphatidylserine (PS) related to memory. The effects might go away if you take it for a longer period. Note also that PS from soy is different than PS from bovine. Most studies were done with bovine PS. Further, there are few recent clinical studies, so it seems that researchers have lost their interest in PS. However, maybe it helps a bit.
Michael, I make reference to 13 clinical studies for this video and transcript. And while the science is important, I think more important is *_how it feels when you use PS as a supplement_* .
This is what users of the bestselling PS supplements on Amazon had to say about using PS as a supplement:
- Boosts energy levels
- Improves alertness
- Less brain fog
- Better memory
- Logical thinking improves
- Concentration is better
- Clarity of thought
- Weight loss
- Easier to remember names, phone numbers, tasks, etc.
- Mood improves
- Anti-anxiety
- Lowers cortisol
- Relieves insomnia
- Vivid dreams
Is this safe to take. I see articles about cancer and a gabba antagonist Thaughts
Gary, no easy answer to this because it is complicated. There are clinical studies being done measuring PS on the outer layer of cell membranes (PS is part of the inner layer of cell membranes) to determine the presence of cancer. Like this study: pulse.ly/jqv46lhm1u. And they are using PS as a targeted therapy for various kinds of cancers.
I have not seen any clinical study suggesting that someone with cancer should avoid supplementing with PS.
Very educational , thank you. Do you recommend 11 years old girl with ADHD and processing problem to take it , if so then how many milligrams. Thank you
Olga, I'm not a doctor so cannot advise you one way or the other. PS would be a good choice however based on my research. If it was my daughter I'd have her using 50 mg per dose.
Thank you. What Brand with 50 mg? Please advise
Olga, look for a patented version using sunflower lecithin like one that uses Sharp PS. I don't think you'll find one with a 50 mg capsule. So you'll need to open the capsule and discard half of the powder.
I just came across this video. I wish I had seen it sooner. I wanted to ask can I give PS to my autistic child? She is 5years old and is non verbal. Also which brand and how much do you recommend I give her?
I have not come across any research showing PS helps with autism. This is a link to my article about nootropics for autism which may help: nootropicsexpert.com/unlocking-the-benefits-of-nootropic-supplements-for-autism/
Hello sir, serine seemed to be more expensive than choline in supplement form here in the market.. is it just ok to opt for choline, since choline can be synthesized as serine? or is it not as effective than taking serine itself? my main purpose is to improve my memory, thank you.
The thing is regular choline has a hard time getting into your brain. The only choline supplements with true nootropic value are Alpha GPC and CDP-Choline (Citicoline).
Should I be taking it on empty stomach? Thankyou for another amazing video.
Praveen, phosphatidylserine is a fat-soluble so must be taken with a healthy fat for it to work. Like a tablespoon of unrefined coconut oil, MCT Oil or Extra Virgin Olive Oil.
NootropicsExpert Thankyou 😊
@@user-pw8jk5ug6c Fish oil supplements are useless and are often toxic. For nootropic use I suggest using a DHA supplement instead.
Which DHA supplement do you recommend?
@@PG-on1dx bit.ly/3kgtQ12
awsome information thank you
Thank you Charlie.
Are any ricks when combined with Acetyl-L-Carnitine?
Pedro, the only "trick" is to use recommended dosages for each if you want the full benefit of each nootropic.
I am looking for the best phosphatidylserine or PS supplement out there. I prefer Non GMO derived from Sunflower Lechithin?
Bruce, then you want a PS supplement using Sharp PS Green like this one: amzn.to/3wYgkpg
Does Phosphatidylserine work well alongside Elvanse the latest ADHD?
Hugh, some consider PS the be the best nootropic we have for cognitive health. But if you're using any stimulant drug for ADHD you'll get much better results with a good ADHD stack which is explained in this video: ua-cam.com/video/S5eKdEZDdBM/v-deo.html
Before I watched your video, I bought PS and the dosage is 2 caps (500 mg). Is it okay to take this much or should I lower the mgs by taking only one?
PS is fat soluble and you only need 300 mg per day. So, one cap of that supplement will provide 250 mg that if used consistently and long-term should provide the benefits I mentioned in this video.
Good morning! It must be taken in gastro resistant capsules?
Bruno, PS can be in veggie or or regular capsules. But it must be taken with food with some oil or fat in it. Or a tablespoon of unrefined coconut oil or extra virgin olive oil for absorption. Because it is fat-soluble.
@@NootropicsExpert Thank you 🙏
Can i use this with cdp choline and omega 3 ?
Yes
Can i take it with piracetam and citicoline?
Yes you should be able to use them in combination.
my naturopath doctor who I think is just in it for the money.....wants to give me a drip using phosphatidyl choline for sleep but I think he has the wrong amino acid.....it is phosphatidyl serine that helps with sleeps because it lowers cortisol....am I right..????
Diane, you are correct. It is PS that lowers cortisol.
what do you think of a psych. doctor who wants to give you between 10 to 30 infusions into your vein in your arm of the other phosphatidyl ......isn't that dangerous??? once a week he has some nurse come in and do an inter veinous(spelling) of this amino acid.....he claims it will help me come off a benzo (klonopin)......I think this is a dangerous fad and then he says,"oh, you can take the phosphatidyl serine in tablet form.....how many mgs in tablet form for lowering of cortisol and which company would make the best tablet.
@@dianelindenberger6941 Diane, some use PS infusions as an anti-aging protocol. It's not dangerous. If taken as a supplement it's 100 mg 3-times per day. And look for one that uses Sharp PS Green like this one: amzn.to/3bUb3FC
Is this the same as L-serine?
Negative. Phosphatidylserine (PS) and Serine are two different compounds. One is a phospholipid and the other an amino acid.
I need cortisol boost in the morning since I always sleep during the day and wake up the night any suggestions?
The easiest and most effective way to boost cortisol is with caffeine.
@@NootropicsExpert but it has many side effects... I have another question I have low blood pressure and I'm taking L tyrosin and 5htp which lowers it even more I've heard this medications is effective or do you recommend other ways that I can increase it?
@@nazigol289 You are not likely using enough Tyrosine. The normal recommended dose if 500 mg 2 or 3-times per day.
And 5-HTP is not a great idea anyway. Why are you using it? If it's for sleep a far better choice is 500 mg L-Tryptophan.
does this supplement actually worsen dementia ?
Irwan, exactly the opposite. Dementia is associated with a deficiency in DHA (Omega-3) and Phosphatidylserine.
Anyone how do you take it can you take it on empty stomach or with food
Phosphatidylserine is fat-soluble so needs to be taken with a healthy fat for your system to absorb and use it. Otherwise, it will be excreted out of your system unused.
is it okay to take Phosphatidylserine and L-tryptophan together?
Yes you can Harvey.
@@NootropicsExpert Thanks for the response. Can you give me an advice when to take L-tryptohan, Phosphatidylserine and L theanine? what is for day and what is for evening?
@@Harvz02 L-Tryptophan about 60 minutes before bed. Lower dose L-Theanine can be used during the day but no more than 100 mg. Higher doses taken at the same time as Tryptophan.
And Phosphatidylserine dosage is 100 mg 3-times per day (morning, noon and late afternoon).
Can you build tolerance ?
Not if you use the recommended daily dosage of 300 mg per day.
I heard you should you use 800 milligrams of PS
Whichever works for you best.
Should a 17 yo Take Phosphatudyalserine ?
Watts, google or search for "Phosphatidylserine: Benefits for Children" and you'll get a doc that shows the list of clinical studies for PS used in teens.
You're almost as good as Joe Biden reading the prompter, lol. Just razzing you, I love what you do though.
I am getting a proper teleprompter so no one is tempted to 'raz' me.