What is Atypical Depression?
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- Опубліковано 8 чер 2018
- This video describes atypical depression. When we talk about the term atypical depression, what we're usually referring to is a specifier referred to as “with atypical features.” This specifier is available for major depressive disorder, persistent depressive disorder, and bipolar disorder. This is not a subtype of these disorders, but rather a specifier, so it adds more information to the diagnosis. In order for the with a typical features specifier to be added to a diagnosis, separate criteria have to be met in addition to the criteria necessary for that primary diagnosis. The symptom criteria for the specifier need to be present the majority of days in the current or most recent major depressive episode, or in the case of persistent depressive disorder, just in the course of persistent depressive disorder. Criterion A is mood reactivity and this is required. This is when someone feels a little bit better when they hear good news. In Criterion B there are four symptom criteria and at least two have to be met: significant weight gain or an increase in appetite, hypersomnia, leaden paralysis, and interpersonal rejection sensitivity. Criterion C is the symptoms for with melancholic features and with catatonia cannot be met. The atypical depression specifier can't exist at the same time as melancholic features or catatonia. Atypical depression is actually not that unusual. It affects about 15 to 40% of individuals with major depressive disorder and about the same percent of individuals with bipolar disorder. There are some characteristics that are associated with atypical depression that we don't see with major depressive disorder with another specifier or without any specifiers. For example, certain personality traits tend to be more common in atypical depression, like the traits seen with borderline, histrionic, and avoidant personality disorders. With atypical depression we also see an increase risk of suicidal behavior and increased comorbidity with other mental disorders.
This is just my opinion, but I have done a lot of research and I think this is actually a completely different illness than major depressive disorder, and trying to stuff it into the same slot as MDD has resulted in under-diagnoses, and mismanaged treatment. I believe it is caused by a specific brain chemistry dysfunction involving dopamine; specifically, a down-regulation of dopamine in the hypothalamus-pituitary-adrenal (HPA) axis, and is differentiated from Parkinson's disease only in the actual location in the brain of the dopamine receptors that it affects. It's symptoms are truly bizarre, and traditional antidepressants won't touch it. In fact, non-responsiveness to traditional antidepressants used to be an actual listed diagnostic criteria in previous revisions of the DSM. My personal experience is that after trying so many things that did not work, I finally got relief from taking selegiline at a higher, nonselective dosage of 40 mg per day. --> Again, I am NOT a physician, nor a mental health professional, and all of this is my opinion and nothing else.
I also experience these symptoms, and respond to bupropion (wellbutrin) which works on dopamine more than SSRI's..
Thank you for all your clearly explained videos. You have a very calming and soothing voice, makes for easy listening. Keep up the good work.
You're welcome, thank you so much for the encouragement!
This was a great video explaining Atypical Depression. I also found it interesting that certain personality traits are more common in developing Atypical Depression and are similar to those found in Borderline, Histrionic, and Avoidant Personality Disorders.
Very interesting to hear with atypical depression specifiers, someone may experience a positive mood. this is something new that I learned.
I also noticed this and found it very interesting that positive reactivity was a criteria or atypical depression.
I wonder if people with atypical depression ever feel like they're faking their depression because they feel happiness
It’s interesting that one of the criteria that has to present for diagnose is that good news make mood better. Your explanations were specific and informative.
The last couple videos have talked about specifiers and I'm wondering if a person with a mental health disorder can have more than one specifier attributed to them? I may have missed it if that was stated in a video but nonetheless I am still confused about that concept. I would like to think that it is possible since some disorders can be co-morbid but a definitive answer would be appreciated.
I find it very interesting that the amount of sleep one gets or does not play a big role in these disorders.
I find it very interesting that the atypical depression specifier can't exist at the same time as melancholic features.
Thanks doc excellent video. So you do one on one work? Pretty sure what you’ve described is what I have. Many thanks
I’ve got atypical depression. That’s why I’m here.
It's interesting that the specifier can fluctuate between melancholic, atypical or no specifier. It appears that energy and reactivity differentiate the atypical and melancholic specifier.
I wonder why there would be an increase in suicidality with this specifier? Especially when one of the requirements in Criterion A is that good news makes the person feel a little better.
This sounds interesting. The interesting symptom is someone sleeping alot more than usual.
It would be interesting to know what research identified this sub-set of depression. I presume that there must be some correlation found between a depression that is reactive to good events and leaden limbs or sensitivity to rejection. The reason why those things would be correlated is not obvious (at least not to me), so it would be interesting to know how it was identified.
I have also read quite a lot about Atypical Depression being highly linked to maladaptive personality traits or personality disorders specifically.
Would the term "non-indigenous depression", which is also highly linked with personality disorders, be synonomous with atypical depression?
I'm guessing that the key differentiation would be that non-indigenous depression is defined as depression that eleviates when exposed to positive external events or worsens with negative external events (where as indigenous depression doesn't significantly react to external events), and that atypical depression could be defined as non-indigenous depression, but could also be when there is a manifestation of atypical symptoms that occurs in indigenous depression.
Wow 15-40 % of those diagnosed have atypical depression.
Very interesting video. What is the difference between atypical depression and melancholic depression. ?
It seems like serum concentration of vitamin d is enough for Patients with atypical depression, but not for melancholy type. MAOI can be applied to atypical depression. It seems like some type of tobacco leaves contain MAOI. Its base structure is a quinone and vitamin K has the same base structure. Do they need high dose of vitamin K ? For hypersomnia, calcium may be deficient. Calcium / magnesium ratio may need to be balanced with vitamin D3 and vitamin K2. Further, arginine or ornithine is good for me to get up early.
What are the meds typically prescribed for atypical depression?
My IQ isn’t high enough for this video
Still a good video though
What would be the best type of medication for atypical depression besides Bupropion?
Can stimulants such as ritalin be use for treating this type of depression?
I like your video and your engergy but this is a little hard for me to understand
If you live in America, you're probably under-employed or not employed at all, have no career or one to look forward to...of course you are depressed.