PATHOLOGIC CALCIFICATION: Dystrophic & Metastatic Calcification
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- Опубліковано 10 вер 2024
- A series of video tutorials discussing the pathology of cell injury and adaptations.
In this tutorial , i have discussed Pathologic Calcification.
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PATHOLOGIC CALCIFICATION
Abnormal tissue deposition of calcium salts, together with smaller amounts of iron, magnesium, and other mineral salts
DYSTROPHIC CALCIFICATION
Occurs locally in dead and degenerated tissues
Normal levels of serum calcium
Absence of derangements in calcium metabolism
METASTATIC CALCIFICATION
Deposition in normal tissues
Increased levels of serum calcium
Disturbance in calcium metabolism
(in hyperparathyroidism, bone damage or diseases etc
METASTATIC CALCIFICATION
1. 4 Primary causes
1. Elevated PTH causing bone resorption
1. Primary hyperparathyroidism : adenomas
2. Secondary hyperparathyroidism : paraneoplastic syndromes
2. Destruction of bone, in tumors like myeloma, leukemia and other tumors
3. Vitamin D related disorders like intoxication - increased absorption of calcium
4. Renal failure (phosphate retention so increased PTH)
2. Occurs throughout the body but favors tissues that excrete acid - ( internal environment is alkaline) favoring calcium deposition.
3. Gastric mucosa( around fundic glands), lungs ( alveolar wall), kidneys( tubules)
Morphology
Macroscopy: Can vary in size, white granules which may be gritty
Microscopy: Basophilic, amorphous or granular appearance/ in clumps.
Intracellular, extracellular or both in H & E stained sections
• Psammoma bodies: concentric laminations of calcium deposition.
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Please watch: "WARBURG EFFECT: Hallmark of CANCER. What, Why & How?"
• NEOPLASIA 6: WARBURG E...
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The “ thanks for watching” should change to “ you’re welcome for watching” cause your videos are short and very helpful.
You are making the students...fall in love with pathology
Too good , short summarized and upto the points ! I loved it sir
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Great video, Clear and straight to the point 😃
Thank you for these wonderful videos sir, they are really clear and to the point.👌🏻
Could you pls make videos on leukemias
thank you so much for this video, i have understood clearly, i had no difficulties at all
Excellent video 👌
Concise and crisp
Thank you very much sir
Very helpful 👌👌👌
This video was great. Thank you Sir :)
Thank you for this video..
It was very easy to understand 🤩
Thanks a lot
Thanks sir,,, plz upload hematology basics..
Thank you
Amzing. I loved it. Thank you sir.
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Amazing tnq sir
Thank You Sir...!
Its really use full video sir❤❤❤
Thank u so much Sir...Clean & Crisp
Thankuu sir
Thankyou
thanks sir, very helpful
Thank you sir 😇
So is this enough fr writing in 10 mark or 5 mark qn ?! Sir
Thank you so much sir😊
Very nice
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Nice explanation
Thanku
Sir your videos are very helpful 💥
Thank you So much sir💫🙏🏻
Thank you :-) Shall be adding more videos.. Do circulate among your friend if you find them useful :-)
@@ilovepathologyVijayPatho Sure sir😊
Great
Thank.you.so.much.sir.
How will be appear calcium in H & E staining
And how will be calcium appear in fixed tissue
Make a video on proteins accumulations as well!!
Thank u
3:08 thrmobotic venous calcification is also called?
Thanks
Thanks sir .😊
Is there any more videos ..
Sir please make videos on cvs
👌👌☺thank you sir
Sir.. I want lecture slides sir.. where can I get it ???
Which book do you follow ??
You should explains the terms also
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Thanks sir
So nice of you
Explain Tamil also sir please
Sir what is H and E stained sections??
Nidhi Rana it's Hematoxylin and Eosin stained sections 😊
😅thank you sir. 😊
Apoorva rani upadhyay 413A
Sir pdf file ah comments la pin panna mudiyuma sir
👍
METASTATIC VERSUS DYSTROPHIC CALCIFICATION
i need English caption
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Bbm kami
💜💜💜🏌️♀️
Wrong
thank you so much sir
Thank you
Thanku sir