PATHOLOGIC CALCIFICATION: Dystrophic & Metastatic Calcification

A series of video tutorials discussing the pathology of cell injury and adaptations.
In this tutorial , i have discussed Pathologic Calcification.
***Follow me****
ilovepathology....
Twitter : / vijaypatho
/ ilovepathology2
Facebook: / ilovepathology
PATHOLOGIC CALCIFICATION
Abnormal tissue deposition of calcium salts, together with smaller amounts of iron, magnesium, and other mineral salts
DYSTROPHIC CALCIFICATION
Occurs locally in dead and degenerated tissues
Normal levels of serum calcium
Absence of derangements in calcium metabolism
METASTATIC CALCIFICATION
Deposition in normal tissues
Increased levels of serum calcium
Disturbance in calcium metabolism
(in hyperparathyroidism, bone damage or diseases etc
METASTATIC CALCIFICATION
1. 4 Primary causes
1. Elevated PTH causing bone resorption
1. Primary hyperparathyroidism : adenomas
2. Secondary hyperparathyroidism : paraneoplastic syndromes
2. Destruction of bone, in tumors like myeloma, leukemia and other tumors
3. Vitamin D related disorders like intoxication - increased absorption of calcium
4. Renal failure (phosphate retention so increased PTH)
2. Occurs throughout the body but favors tissues that excrete acid - ( internal environment is alkaline) favoring calcium deposition.
3. Gastric mucosa( around fundic glands), lungs ( alveolar wall), kidneys( tubules)
Morphology
Macroscopy: Can vary in size, white granules which may be gritty
Microscopy: Basophilic, amorphous or granular appearance/ in clumps.
Intracellular, extracellular or both in H & E stained sections
• Psammoma bodies: concentric laminations of calcium deposition.
~-~~-~~~-~~-~
Please watch: "WARBURG EFFECT: Hallmark of CANCER. What, Why & How?"
• NEOPLASIA 6: WARBURG E...
~-~~-~~~-~~-~

[@Aissa_gilly975]

The “ thanks for watching” should change to “ you’re welcome for watching” cause your videos are short and very helpful.

[@satyanarayankumar9148]

You are making the students...fall in love with pathology

[@nematsache97]

Too good , short summarized and upto the points ! I loved it sir

[@honeyzbest564]

ua-cam.com/video/vdZXTgpLfyc/v-deo.html

[@porikaramkumar5645]

ua-cam.com/video/Tn-YbLvFaMw/v-deo.html

[@bogdansheikh6424]

Great video, Clear and straight to the point 😃

[@farheentahseen3572]

Thank you for these wonderful videos sir, they are really clear and to the point.👌🏻
Could you pls make videos on leukemias

[@Elyasaa1]

thank you so much for this video, i have understood clearly, i had no difficulties at all

[@snehisarda]

Excellent video 👌
Concise and crisp

[@jeremiahbaker6396]

Thank you very much sir

[@rutvikrana512]

Very helpful 👌👌👌

[@poojav4990]

This video was great. Thank you Sir :)

[@30-mniranjanahneeraj39]

Thank you for this video..
It was very easy to understand 🤩

[@fcps_anesthesia]

Thanks a lot

[@ambidextrousdoctor]

Thanks sir,,, plz upload hematology basics..

[@kamelkachin7848]

Thank you

[@freddymontvlinks]

Amzing. I loved it. Thank you sir.

[@porikaramkumar5645]

ua-cam.com/video/Tn-YbLvFaMw/v-deo.html

[@mohitpandey5016]

Amazing tnq sir

[@shahbaz9231]

Thank You Sir...!

[@drtoothkrk]

Its really use full video sir❤❤❤

[@udayakumar3526]

Thank u so much Sir...Clean & Crisp

[@vaishnavivyshu9436]

Thankuu sir

[@medicoanu7210]

Thankyou

[@ikhwanelias9997]

thanks sir, very helpful

[@ambrithasaravana5318]

Thank you sir 😇

[@mummasbabygirl84]

So is this enough fr writing in 10 mark or 5 mark qn ?! Sir

[@108-salinis5]

Thank you so much sir😊

[@kulamanisagar9340]

Very nice

[@honeyzbest564]

ua-cam.com/video/vdZXTgpLfyc/v-deo.html

[@AlimaAktar]

Nice explanation

[@rimonmahmud2864]

Thanku

[@93shreelakshmihs]

Sir your videos are very helpful 💥
Thank you So much sir💫🙏🏻

[@ilovepathologyVijayPatho]

Thank you :-) Shall be adding more videos.. Do circulate among your friend if you find them useful :-)

[@93shreelakshmihs]

@@ilovepathologyVijayPatho Sure sir😊

[@vishalbhartimg]

Great

[@srirambhardwaj2343]

Thank.you.so.much.sir.

[@sarangas8688]

How will be appear calcium in H & E staining
And how will be calcium appear in fixed tissue

[@saranaeem6758]

Make a video on proteins accumulations as well!!

[@drenamul9228]

Thank u

[@talhadange4398]

3:08 thrmobotic venous calcification is also called?

[@kamranbasheer4659]

Thanks

[@mnb7947]

Thanks sir .😊
Is there any more videos ..
Sir please make videos on cvs

[@dr.sravanthisspace]

👌👌☺thank you sir

[@abdulmajithg]

Sir.. I want lecture slides sir.. where can I get it ???

[@shoyaibprojonmo4276]

Which book do you follow ??

[@shifashaikh6999]

You should explains the terms also

[@honeyzbest564]

ua-cam.com/video/vdZXTgpLfyc/v-deo.html

[@danishansari7596]

Thanks sir

[@ilovepathologyVijayPatho]

So nice of you

[@YuvaranikBpt]

Explain Tamil also sir please

[@nidhirana7900]

Sir what is H and E stained sections??

[@ilovepathologyVijayPatho]

Nidhi Rana it's Hematoxylin and Eosin stained sections 😊

[@nidhirana7900]

😅thank you sir. 😊

[@apoorvaupadhyay8917]

Apoorva rani upadhyay 413A

[@prasannadevi8181]

Sir pdf file ah comments la pin panna mudiyuma sir

[@darshanilakmali3523]

👍

[@path4students]

METASTATIC VERSUS DYSTROPHIC CALCIFICATION

[@vipulsaini5348]

i need English caption

[@porikaramkumar5645]

ua-cam.com/video/Tn-YbLvFaMw/v-deo.html

[@justinbasilio1558]

Bbm kami

[@pheonixheart5534]

💜💜💜🏌️‍♀️

[@nabarundebnath9569]

Wrong

[@priyankatiwari3434]

thank you so much sir

[@djethrak4567]

Thank you

[@karthikdrkarthikvarmavet8371]

Thanku sir