Is ARGIRELINE BOTOX IN A BOTTLE? 🤔 DERMATOLOGIST

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  • Опубліковано 4 сер 2024
  • Is ARGIRELINE BOTOX IN A BOTTLE? 🤔 DERMATOLOGIST ‪@DrDrayzday‬ on BOTOX IN A BOTTLE CLAIMS ABOUT ARGIRELINE. DOES ARGIRELINE REALLY WORK LIKE BOTOX? BOTOX ALTERNATIVE FOR WRINKLES? #antiaging #antiagingskincare #dermatologist
    References
    Reddy BY et al. Exp Dermatol. 2012 Aug;21(8):569-75.
    Blanes-Mira C et al. Int J Cosmet Sci. 2002 Oct;24(5):303-10.
    Wang Y et al. J Cosmet Laser Ther. 2013 Aug;15(4):237-41.
    Wang Y et al. J Cosmet Laser Ther. 2013;14(2):147-53.
    Raikou V et al. J Cosmet Dermatol. 2017 Jun;16(2):271-8.
    Kraeling ME et al. Cutan Ocul Toxicol. 2015 Mar;34(1):46-52.
    Hoppel M et al. Eur J Pharm Sci. 2015 Feb 20;68:27-35
    FTC: This video is not sponsored.
    0:00 Botox in a bottle
    0:23 What is Argireline?
    0:47 How Botox works
    2:04 How does Argireline work?
    2:42 Research on Argireline for wrinkles
    8:23 Does Argireline work like Botox in a bottle?
    💜Follow me on liketoknowit www.liketoknow.it/drdrayzday
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    PO Box 542234
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    Disclaimer: This video is not intended to provide diagnosis, treatment or medical advice. Content provided on this UA-cam channel is for informational purposes only. Please consult with a physician or other healthcare professional regarding any medical or health related diagnosis or treatment options. Information on this UA-cam channel should not be considered as a substitute for advice from a healthcare professional. The statements made about specific products throughout this video are not to diagnose, treat, cure or prevent disease.
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КОМЕНТАРІ • 967

  • @AstarteElviraLyana
    @AstarteElviraLyana Рік тому +477

    Short answer: Does not work like botox in humans
    Pre clinical trials suggest it is similar to botox
    Mouse studies suggest it helps with collagen synthesis, but that's not how botox works
    Human study: 30% static wrinkle depth decrease at crow's feet (botox works on dynamics)
    Human study: 48% efficacy in static wrinkles
    Human study: improved skin hydration
    It is unlikely that topical application will be able to get to the muscle, which is where the site of action of botox is

    • @ooOnymphetOoo
      @ooOnymphetOoo Рік тому +41

      Thanks for the summary.
      Even if it won't behave like as botox was injected, it looks promising to give a boost topically. Looks like it could be used along with botox to give the skin extra support. Wonder if everybody else comes to this conclusion as well.

    • @zazzyz4558
      @zazzyz4558 Рік тому +19

      Thank you so much for the summary. Don’t know about everyone else, but I’m not a scientist and don’t really understand how all this works and will surely not remember any of that part. It’s too much. I’d venture a guess that most folks only have time for the bottom line explanation as you’ve provided. Thanks again!

    • @palakush7650
      @palakush7650 Рік тому +31

      You saveeeeed 12 minutes of my lif..wish dr.dray had someone to summarize her vids..they are tooo long sometimes

    • @accesstotheredcarpet
      @accesstotheredcarpet Рік тому +23

      @@palakush7650 Same but that’s what board certified Drs do. They give the medical break down literature. That can be interesting and other times, we just want the short summary synopsis lol 😂

    • @sarkahalastova9667
      @sarkahalastova9667 Рік тому +19

      But the “collagen stimulation similar to tretinoin” part? I think I’m sold.

  • @geriazzolini3293
    @geriazzolini3293 Рік тому +43

    I watch you all the time, FINALLY….a reputable intelligent video with real facts and sincere advice on how to care for your skin! Thank you for sharing your wisdom!

  • @frescazzz7536
    @frescazzz7536 Рік тому +47

    I recently used up a bottle of Good Molecules peptide serum and found it incredibly hydrating. So if nothing else I can definitely attest to the moisturizing properties of it. My skin felt very hydrated and smooth after use.

  • @thejingjingan
    @thejingjingan Рік тому +10

    Thank you Dr. Dray for doing and sharing the scientific research!

  • @88bulldog
    @88bulldog Рік тому +5

    Fantastic video!
    You definitely know your chemistry!
    Keep up the honest and truthful videos🏃🏾‍♂️

  • @alicassidy8913
    @alicassidy8913 Рік тому +13

    I appreciate how you explain in depth. I started using this 2 weeks ago and this does work (for me.). I was feeling down that my face was starting to look old. I'm so pleased. You're awesome Doc ❣️

  • @TM-rc1og
    @TM-rc1og Рік тому +5

    Thanks for the info Dr. Dray! I know I can always get an honest and scientific opinion from you!

  • @jflo2012
    @jflo2012 Рік тому +22

    Been using The Ordinary Argireline twice a day for 10 months on my frown lines (11s) and have seen absolutely no change whatsoever. Won’t repurchase.

  • @elizabethevelyn7125
    @elizabethevelyn7125 Рік тому +42

    This is good info! I'm much more interested in diminishing static wrinkles than preventing muscle movement. Sidenote though, I'm so sick of brands using the term "Botox in a bottle" for every new product that has supposed anti aging benefits 🙄 I've been hearing it for years and it's always about something different than the last

    • @smack6030
      @smack6030 Рік тому +8

      Same! I like my face to have movement (dynamic) but hate when I have wrinkles when not moving (static). So this product, along with its hydrating properties, seems like a product to try.

  • @zsofipapp
    @zsofipapp Рік тому +22

    Thank you for this great video, Dr Dray. I use a serum with Matrixyl3000 and XEP-018 peptide (as far as I understand similar to Argireline) and it visibly smooths out fine lines. However, it does zero to relax facial muscles. I still have to get Botox to prevent headaches. But I've read somewhere that they are working on developing patches to increase the penetration of XEP-018. Who knows, maybe cosmetic applications are also on the horizon.

  • @ItsPouring
    @ItsPouring Рік тому +3

    You are _THEE_ business! Thank you for the details on the clinical research you provide and your down-to-earth (sometimes bubble-bursting ☺) realism - really appreciated! 💖

  • @rebecca4464
    @rebecca4464 Рік тому +41

    FANTASTIC explaination of the chemistry, mechanism, and results. Thank you doctor!!

  • @CloveCoast
    @CloveCoast Рік тому +9

    You got me to buy this at Ulta!
    I run through it quite quickly because the bottle was small and it’s a total liquid not an oil. Pretty affordable though.

  • @carloscarion1748
    @carloscarion1748 Рік тому +197

    I truly admire the manner in which you present your subject matter in your videos, you do the research and you attack(in the most agreeable sense of the word) your subject matter with efficacy, informing your viewers, leaving no questions unanswered, or doubts (for the most part), which may arise. Your presentations (in my humble opinion), are akin to an art form, and I for one, look forward, always to viewing your videos, knowing I will be the wiser and more fully informed for them. Thanks for your passionate attention to the subjects at hand. Be well, much success to you

  • @bethhan3218
    @bethhan3218 Рік тому +1

    Thank you for taking the time to make these videos.

  • @glendagai
    @glendagai Рік тому +1

    Love Dr. dray… my confidence is in her. I check out any decisions I make with her wisdom.

  • @EMILYHERRERA
    @EMILYHERRERA Рік тому +4

    Your content and presentation style is unmatched!

  • @hannahespina8521
    @hannahespina8521 Рік тому +92

    i've been using the Ordinary Argireline & Matrixyl combo for at least six months now and I've seen some improvement in the fine static wrinkles starting to form on my top forehead. It's certainly not an overnight sensation, but enough that I've kept it in my routine. I do find the combo of peptides to improve hydration, and maybe that's why the static lines look less prominent? At the price point and with zero irritation or side effects, I've been happy to keep it on the routine-- for now :) Thanks for breaking down the studies on Argireline for us!

    • @matejhacko6031
      @matejhacko6031 Рік тому +4

      Hi, may I ask when do you apply Argireline? What part of your routine do you apply it in? thanks!

    • @kindramurphy8925
      @kindramurphy8925 Рік тому

      Same

    • @MsElectricsurge
      @MsElectricsurge Рік тому +2

      I use it right after cleansing and concentrate on the areas I want the improvement in. I saw good results.

    • @milenaandonov9291
      @milenaandonov9291 7 місяців тому +3

      Hi! How often are you using it and can you combine it with vitamin C and retinol?

    • @Matt-uv2yg
      @Matt-uv2yg 6 місяців тому +1

      Hey! Are you still using it now, a year later? Curious to hear

  • @annewatkis5824
    @annewatkis5824 Рік тому +1

    Love your videos Dr Dray. My skin loves you too. All the advice and information you provide. Thank you xxxx

  • @JolieFleur0116
    @JolieFleur0116 Рік тому

    I loved this informative video! I especially appreciated the research behind the video.

  • @satutoivonen9679
    @satutoivonen9679 Рік тому +10

    Thanx, this was super informative & interesting! I love it when dr. Dray explains science, she's really good at making science understandable.

  • @aflilly
    @aflilly Рік тому +54

    I really appreciate this video. As a cosmetic chemist, I get questions like this all the time. The biggest difference I can say is that anything topical is not as efficacious as something that is injected. A majority of the skincare products in the market is so heavily marketed beyond it’s true capabilities. Personally, I am lucky enough to make my own skincare as opposed to wasting it on uber-boosted products. Lee up the great videos!

  • @jeanineross8457
    @jeanineross8457 Рік тому +2

    Love when you break down and talk about actual studies out there. The beginning was a little hard to follow but love the research parts

  • @archiegaming525
    @archiegaming525 Рік тому +1

    Thank you so much, Dr dray, the answer I was looking for. Have a blessed day! 💕💕❣️

  • @marilynkennedy1579
    @marilynkennedy1579 Рік тому +3

    I’ve been using Wrinkle Smoother Lips from Merle Norman for maybe 10 years after looking for products made with argireline. I have almost no lip lines at 61 years old and plan to always use this product. Will try The Ordinary for forehead and eyes.

  • @lauriewarner4848
    @lauriewarner4848 Рік тому +6

    Once again you are incredible at delivery of incredible information that we understand, with a no nonsense agenda! We all love you!

  • @margieryne6220
    @margieryne6220 Рік тому +1

    Thank you for this information, I truly appreciate it!🥰

  • @DiggingtheJive
    @DiggingtheJive Рік тому +1

    Thank you for your posts/reels/shorts/videos/vlogs. They are informative and have helped me on my journey to clearer, more even-toned skin.
    If you have a chance to try these products, I’d love to hear your thoughts on the Summer Fridays Shadedrops Broad Spectrum SPF 30 Mineral Milk Sunscreen and Summer Fridays Sheer Skin Tint with Hyaluronic Acid + Squalene. Thanks!

  • @GenXfrom75
    @GenXfrom75 Рік тому +5

    I had some in my The Ordinary cart! I'll see what you say about it before checking out! 👍✌️💯 I'm not AT ALL expecting Botox-like results, however. I'm always realistic in my expectations from skin care.

  • @magdalenaarcia3324
    @magdalenaarcia3324 Рік тому +11

    I'm on my first bottle of it and have seen some improvement on wrinkles around the mouth region. It's not Botox, but it has its place in skincare.

  • @collettemarquez7851
    @collettemarquez7851 Рік тому +1

    Thanks Dr. Dray! You are so helpful!

  • @amandak572
    @amandak572 Рік тому +2

    I use argireline and I have had good results while using it, but I have also done something else simultaneously, so I don’t know which one to credit more. The other thing was a home eye peel kit, which contained a bottle of 7% TCA, 35% matrixyl synthe 6 and a 0.5% retinol serum, which I was suppose to use together once a month. I used argireline twice a day and and used the natural moisturing factors over it. I am 32 and I started to see some small lines forming on the side of my eyes last year. Now they are gone. I’m not sure if I could call them «dynamic wrinkles» but they were there in the morning when I woke up, and they annoyed the heck out of me. I have done 4 eye peels. One time 1 layer of TCA, one time 2 layers TCA, two times 3 layers Of TCA. My last eye peel was in march. The wrinkles have not come back. If I laugh and smile a lot, they may form, but they «bounce back» if that makes sense.

  • @tracywestwood7642
    @tracywestwood7642 Рік тому +57

    Thank you Dr. Drey! I have been using Argeraline for about three weeks and I have definitely noticed improvements re: fine lines and wrinkles. I wouldn't say that the results are like Botox, but the improvements have been significant enough that I will continue to use it. It is subtle, but, as my husband says, I definitely look "younger and fresh". Also, I think it could be used along with Botox to possibly extend the Botox resuls ??? Not sure, but possibly. Thanks again for a of your wonderfully informative videos!

    • @Alexcocomommy
      @Alexcocomommy Рік тому +2

      hello ...is it from Ordinary ?

    • @tracywestwood7642
      @tracywestwood7642 Рік тому +1

      @@Alexcocomommy I have been using Asterwood Naturals, but The Ordinary has a great product too!

    • @askhanofficial6884
      @askhanofficial6884 6 місяців тому

      Did you use it only during the day ?
      My night application of argeraline caused sagging , after 3 days I stopped . I started looking 10 yrs older

  • @katetsirkunov
    @katetsirkunov Рік тому +8

    Always informative! I was also very suspicious when I saw that “botox in the bottle” video. You cannot simply compare products with different delivery systems 😅 stratum corneum is the most challenging skin layer to penetrate through

  • @a404280
    @a404280 Рік тому +2

    Great video! Thank you so much!

  • @ajalondon7578
    @ajalondon7578 Рік тому +2

    I use the biossance peptide eye gel with argireline and have noticed dramatic softening of my under eye lines. I don’t think it’s as effective as Botox but I’m very pleased with my results.

  • @melissastarr7451
    @melissastarr7451 Рік тому +6

    I think the fact that it affects static wrinkles while Botox affects dynamic wrinkles is potentially a really good combination if you were to do both.

  • @theabbyalexa
    @theabbyalexa Рік тому +45

    Always sooo informative, thank you Dr. Dray!

  • @sonyahuffman8235
    @sonyahuffman8235 Рік тому +1

    Thank you for the truthfulness

  • @JuanGarcia-eh7zn
    @JuanGarcia-eh7zn Рік тому

    I love videos like this. is there any way that you could do something in this same style for 3-O-ethyl ascorbic acid and whether it actually penetrates the skin more efficiently and works for the stuff that companies claim itdoes

  • @barbarabraue4087
    @barbarabraue4087 Рік тому +23

    This is so funny that you did this video because I was in Ulta over the weekend and a sales lady was giving me the pitch of “Botox in a bottle” with one of The Ordinary products. I said to myself, sure lady. I did not buy it but maybe now I might try it. I really don’t care if it isn’t Botox just something to help plump my wrinkles would be great. Thank you for breaking it down for me.

  • @dianaford003
    @dianaford003 Рік тому +495

    I used to use Botox religiously, but it started wearing off within a couple of months. And spending $500 every few months isn't happening! So I tried the Ordinary's Argireline, and...it's AMAZING! I haven't needed Botox in about a year now! The only advantage I can see with Botox is that it does give me a slight lift of my eyebrows and lip, but my wrinkles are gone either way. I will never be without Argilerine!

    • @elizabethjones2084
      @elizabethjones2084 Рік тому +18

      For real???

    • @dianaford003
      @dianaford003 Рік тому +43

      Yup. I still have a tiny line (elevens) that would go away with Botox, but I don't have crow's feet, and my forehead lines are minimal. That said, I'm also doing a ton of skincare, including tretenoin...but argireline has really helped keep me from feeling like I need Botox. I can tell the difference when I stop using it!

    • @walkingbyfaith2885
      @walkingbyfaith2885 Рік тому +17

      I Desperately need help with my " Elevens" on forehead between Eyebrows 😣

    • @bettypogh3910
      @bettypogh3910 Рік тому +3

      which brand did you get, can you send the exact name please. thanks

    • @salandersalgado4038
      @salandersalgado4038 Рік тому +23

      You work for Ordinary 🤣

  • @DrReedB0928
    @DrReedB0928 Рік тому +1

    Great topic! Happy Wednesday Dr.Dray and peeps ☕ ☕ 🍵 🍵 ❤️ ❤️ 🌞 🌞

  • @lisaflanagan5993
    @lisaflanagan5993 Рік тому +3

    I use Botox, and find it helpful. But, what I appreciate about this video is the integrity that comes across. No trickster stuff. Thx for that.

  • @catgirl444
    @catgirl444 Рік тому +140

    Here’s my experience with it. I purchased it because I read it was like Botox in a bottle; I don’t have wrinkles so I didn’t really expect to see much of a change, and as someone who’s never tried Botox before I was just curious.
    I NEVER knew my skin could use the extra “lift”, because that’s basically what it did for my skin. I have chubby cheeks, which always sagged but it lifted it. My skin looks MUCH younger, it’s almost eery.
    I also have a dehydration line under my left eye, so I applied Argireline under it and it’s gone.
    It works like Botox. I understand it doesn’t Literally work like Botox, but it gives similar results as Botox , from my experience. I’m obsessed with it, mostly since I’ve only been using it for 2 weeks.

    • @The_New_Abnormal_World_Order
      @The_New_Abnormal_World_Order Рік тому +10

      I definitely want to try it now. I used to think the entire anti-aging industry was a scam! But I'm actually feeling more hopeful now. I have ordered some tretinoin and plan to try this as well. Wish me luck.

    • @ericachitwood2465
      @ericachitwood2465 Рік тому +3

      What brand are you using? I'm finding that not every product is made equally and I'm struggling to find a good one

    • @lidiavalentine4296
      @lidiavalentine4296 Рік тому +2

      Oh wow! Nice hu 😊

    • @ItsPouring
      @ItsPouring Рік тому +1

      Hey wow! Cool! Thanks.

    • @carter_tate
      @carter_tate 7 місяців тому

      Which product are you using!?

  • @raypicard8263
    @raypicard8263 Рік тому +6

    I really like your honest knowledge about skincare ..I have learn so much from your channel now I don't feel like such a sucker for skincare products. Thanks Dr Dray 😊

  • @dzingunyte
    @dzingunyte Рік тому +2

    Terrific video as always, Doc!

  • @jcjmljh
    @jcjmljh Рік тому +1

    thanks for this video! i was just going to buy some but i think i will hold off

  • @Piddeaux
    @Piddeaux Рік тому +7

    I just started using an Argireline/Matrixyl product in my nighttime skincare routine. Haven't used it long so I can't say how it benefits wrinkles but I think it's safe to say that it doesn't irritate, burn, or sting. That's saying a lot for me. I like the way it feels and the product I found isn't hugely expensive so all things considered I'll keep using it unless something changes.

    • @Jessica-iq6kj
      @Jessica-iq6kj Рік тому +1

      Hi, any update? I'm considering purchasing these two products.

    • @ojjordan7904
      @ojjordan7904 Рік тому

      Can I ask you where do you buy it?

    • @Jessica-iq6kj
      @Jessica-iq6kj Рік тому +1

      @@ojjordan7904 you can find it on Amazon.

  • @monicaduncan7109
    @monicaduncan7109 Рік тому +17

    Thank you Dr Dray so many skincare influencers are pushing this as Botox in a bottle. It can’t possibly compete with the real Botox! Thank you for always keeping it real

  • @nathanbradleyf777
    @nathanbradleyf777 Рік тому +1

    I was wondering what this stuff was when I saw it at Ulta. You look so good these days. So much healthier and pretty. You were always pretty but you look even better lately.

  • @GMaryG89
    @GMaryG89 Рік тому

    Love you Dr. Dray! Would you consider reviewing Honest Beauty's new acne skincare products???

  • @msolounias
    @msolounias Рік тому +4

    I use this chemical and have great skin, however I cannot definitively confirm its efficacy due to my retinoid usage which has actually been thoroughly researched and has shown to improve acne and skin aging.

  • @magickmagazine7675
    @magickmagazine7675 Рік тому +11

    I imagine it penetrates to the NERVES like topical anesthetic and works on the nerves rather than the muscles - But I can tell you after using it for months and months it really does work - huge difference

    • @happymess3219
      @happymess3219 7 місяців тому

      that's what i was thinking too.
      something like 'orajel' or 'icyhot'.

  • @montananerd8244
    @montananerd8244 Рік тому

    I have only been using argirilene a few weeks, so not expecting results yet, but I did see one area of major improvement: those horizontal cheek lines you told us about. I can still see a bit of redness where the wrinkle was, but it's plumped up to nearly disappear! I'll probably try it for a year, then assess, but I've definitely got to get rid of some products. Love the feel of PGA & q10 but suspecting they aren't really doing anything but a touch of plumping, an extra layer of gold bond might do the trick lol. I should test them vs my plumpy primer, but the overall cost is the same...

  • @karentrail8077
    @karentrail8077 11 місяців тому +2

    I really appreciate your skin video’s. Your advice has been the catalyst for many of my skin protocols.
    Personally, I have Botox injected and use Argireline and both work miracles.

  • @katerynasayin5548
    @katerynasayin5548 Рік тому +7

    Hello, Dr Dray! ☺️
    Thank you so much for such detailed information on this product! 💪🏻🙏
    Could you please advise on how to incorporate this product into a daily skincare routine and what’s the best way to layer up the products (incl. retinol serum and BHA toner)?
    Many thanks!

    • @L_San87
      @L_San87 Рік тому +2

      Hi! Ik I'm not dr. Dray but I do use this product for a long while and have seen results. I use it after my toner and essence because it needs the moisture and I don't use it with any other actives like vit C or retinol.

    • @nasimaaftab7326
      @nasimaaftab7326 Рік тому

      @@L_San87 m using tretinoin for last one month and now i have heard about this product can u advise how to use it with tretinoin… can we use it on trét off days?

    • @L_San87
      @L_San87 Рік тому +1

      @@nasimaaftab7326 hi! Well I couldn't advise you because I never used tret I do une retinal and I did avoid any other serums on that day, all I did was toner/essence and retinal followed by moisturiser. I believe it can be used since is a peptide but I prefer to use vit. A on its own as it is a powerful active. The morning after I did apply it and it helps with moisture.

  • @Yourdeadmeat69
    @Yourdeadmeat69 Рік тому +4

    Instead of trying to pierce the outer skin layer down, use NIACIN FLUSH to dilate the capillaries and bring blood up to the very highest layers of the skin. I do this with topical minoxodil and the results are great!
    Whattya think?

  • @Ilove_gtag7
    @Ilove_gtag7 Рік тому

    I have been waiting fro this one!!! Thanks Dr. Dray!

  • @royaaa
    @royaaa Рік тому

    your eye area has been looking so good and fresh in your recent videos, do you mind making a new updated video on eye treatments? 🌹

  • @InfinityHealthPilates
    @InfinityHealthPilates Рік тому +6

    I have used it on and off throughout my life and always get good results. Currently I’m using the Bobbi Brown repair eye cream intense which has Argeriline in it and I have to say it does relax or maybe hydrate my under eyes significantly. Thanks for all your

  • @angelinebiswas7611
    @angelinebiswas7611 Рік тому +139

    I’ve used argireline combined with the ordinary matrixyl which is actually better than other matrixyl serums because it contains matrixyl 3000 as well as matrixyl synthe 6. I haven’t found any other matrixyl products that combine both in one bottle. When used together I notice the 11 in my forehead is almost impossible to move. It’s the only place on my face that this does it to. I don’t get Botox in my 11’s anymore because my injector said there’s nothing to fix! But I do not notice any stopping of the creases in my eyes or any other part of my forehead. I used to have a super deep line where the 11’s are and do not have this anymore. I cannot physically make my muscle move to make the line there. I’ve never used anything like this. I feel like it should be used with matrixyl 3000&synthe 6 for better results tho.
    1 important key note is, if I skip a few days,the movement ALWAYS comes back

    • @candacefife6763
      @candacefife6763 Рік тому +4

      I use these 2 combined also.

    • @meganNefarious
      @meganNefarious Рік тому +17

      That's interesting because it cannot penetrate into the muscle so not sure how that's possible..

    • @marymenas
      @marymenas Рік тому +1

      What is 11 ? Lol sorry my ignorance

    • @marymenas
      @marymenas Рік тому +2

      @@candacefife6763 hi! Together or separate? And if such what brands do you buy and when did you start seeing results? Thank you so much

    • @sevinjaa655
      @sevinjaa655 Рік тому +1

      Hi, thanks for sharing this. how long did you use it before starting to see any result?

  • @Nikki30288
    @Nikki30288 Рік тому +1

    Genuinely, I have been to several different dermatologists and none of them give this information! Thank you !

  • @msfoxfgcu
    @msfoxfgcu Рік тому +1

    Wow...I learn something new and so relevant every time I watch your videos!!

  • @naightengale101
    @naightengale101 Рік тому +72

    I used it just this morning as I was feeling extreme tension in my forehead (because my eyebrows tend to rise under stress) and felt noticeable relief (as in less tension). It appears to have an impact.

    • @matthewbelike
      @matthewbelike Рік тому +10

      It may “appear” to have worked, but based on what we know about it, that may have simply been placebo effect.

    • @naightengale101
      @naightengale101 Рік тому +5

      @@matthewbelike that's right. We'll have to wait on a study to confirm (that I, like others, wasn't imagining) the relief I felt.
      It was kind of like when you rub a tense muscle and get that relief. So, we'll see.

    • @matthewbelike
      @matthewbelike Рік тому +7

      @@naightengale101 Well either way I’m glad that that seemed to give you some relief.

  • @cynthiagalvez6219
    @cynthiagalvez6219 Рік тому +138

    Great informative video Dr. Dray! I went through two bottles of The Ordinary's argireline over about 9 months. After that I did not notice an appreciable difference in any of my wrinkles either static or dynamic so I stopped using it. Thanks for keeping it real and science based for us!

    • @angelinebiswas7611
      @angelinebiswas7611 Рік тому +20

      Used with matrixyl 3000 & matrixyl synthe 6 I think you may find some benefits. I don’t get any benefits with argireline alone but when mixed with the ordinary matrixyl 10% (which is 3000& synthe 6) and see only my 11’s disappear and there’s less movement there. Definitely not a substitute for Botox tho!

    • @l.a.3541
      @l.a.3541 Рік тому +4

      Same for me with 4 bottes.

    • @sregan5415
      @sregan5415 Рік тому +7

      @@angelinebiswas7611 How do you know that the argireline worked at all then? Does it work synergistically with matrixyl, is there any science on that? Or was it just the matrixyl that worked for you?

    • @walkingbyfaith2885
      @walkingbyfaith2885 Рік тому +3

      @@angelinebiswas7611 TY , I didn't use with Matrixyl, I have Matrixyl, didn't know I should,

    • @itsme_shanti
      @itsme_shanti Рік тому +9

      @@l.a.3541 did you use as directed? The Ordinary Argireline Solution is meant to be used on very moist skin and not layered with direct Acids or VitaminC. If it's applied to dry skin it will not work. Many moisturizers also contain vitamin C and direct Acids.

  • @andrewsun8773
    @andrewsun8773 Рік тому +1

    Could you try the new glow recipe watermelon AHA treatment mask? They say that it's as effective as 10% glycolic acid but with no irritation, and I was curious about it. No worries if not. Thank you Dr. Dray for all your videos!

  • @lorainemcgillivray77
    @lorainemcgillivray77 Рік тому

    Hi Dr Dray firstly I should say I have never had botox and on a personal level am not currently interested in injectables for the face. At 50 I have both dynamic and static lines/wrinkles, due to having had an expressive face all my life. I like peptides in skincare and different peptides do different things - hydration, calming benefits, slight firming of the feel of the skin and perhaps a little bit of collagen/elastin boosting. I don't however believe they will do what injectables or other more invasive interventions will do. What we use on the skin cannot reach where an injection or surgical procedure will, due to the anatomy of the body/skin. I think retinoids work better for collagen boosting than any peptide does, but peptides are doing other things that retinoids don't. Peptides don't appear to be harmful and don't have to be really expensive. I don't think they're a waste of time, but nor do I think they're amazing or anything like "botox in a bottle". Best wishes.

  • @staceyq5676
    @staceyq5676 Рік тому +36

    Anyone else hoping she would just say yes use or no? Just me…. 😂

  • @StateofKait
    @StateofKait Рік тому +2

    This was so thorough, thank you. I’m going to give it a shot!

  • @gailwood2734
    @gailwood2734 4 місяці тому

    As always, thanks so much for the factual and no nonsense information! This helped me make up my mind to try it or not

  • @sleepingjennifer2
    @sleepingjennifer2 Рік тому +1

    Love your videos!! I would love to see a video on why some brand of face care effect the eyes.( Make them burn)

  • @2preeti4u
    @2preeti4u Рік тому +39

    That’s exactly what I thought. It would be absorbed by the by the epidermis before even getting into the dermis. Botox targets the muscles to inhibit contraction, so argieline solution applied topically might not have the same effect as botox. It’s kind of common sense if you understand the anatomy of the skin and muscles. I can see how it would have a good response on surface level wrinkles. Botox is awesome lol

    • @marylane6835
      @marylane6835 Рік тому +4

      I was almost wondering by the end of the video if argireline would work like Botox when injected in a similar way to Botox. I use Botox for migraines, and it might be nice to have an option that isn't connected to botulism. I also didn't catch what type of human cells were used in the first study discussed. Were they dermis or epidermis? That factor might affect whether injection like Botox would be possible for argireline.

  • @megleland6320
    @megleland6320 Рік тому +101

    I carry a lot of tension in my forehead, and really liked the feel of Botox because it relaxed everything. I let it go over the Pandemic due to all the lock-downs, but now see some of the wrinkles starting to form. I would LOVE it if there was a cheaper option I could do myself, or maybe just to stretch out the time between injections. I am trying to decide now whether to return to Botox or not. This was VERY interesting to watch, but I think I need to re-watch to catch all the info you laid out.

    • @MyrtleBeachWebAngel
      @MyrtleBeachWebAngel Рік тому +14

      Same here. I just ordered this off of Amazon because of another subscriber's recommendation and it was only $13.99. The brand is Cos de Baha with the pink label. I almost bought another brand, Asterwood? but decided to stick with her recommendation. I hope this works. I get the same type of headaches and miss the wonderful relief of Botox, but really can't afford it right now. Wish me luck. 🌼🐝

    • @megleland6320
      @megleland6320 Рік тому +8

      @@MyrtleBeachWebAngel I know what you mean. Going back to Botox would mean taking a hit to other areas of my beauty and entertainment budgets, and everything is going up price ,wise too. Good luck, I hope you get some headache relief!

    • @Noa-g1ex
      @Noa-g1ex Рік тому +2

      Women ☕️

    • @EMILYHERRERA
      @EMILYHERRERA Рік тому +8

      @@MyrtleBeachWebAngel I can't speak for this product, but every cos de baha formula I've used has been GREAT. They have many alternatives to expensive products such as PC BHA toner. Check out their products. I always use their niacinamide and salicylic toner, no matter what. I do try different brands for other things because I like to try different things, but I have no complaints about the many products I've tried, and I've yet to find a better niacinamide or salicylic toner. I'm kind of a product junkie who has tried lots and lots.

    • @MyrtleBeachWebAngel
      @MyrtleBeachWebAngel Рік тому +3

      @@EMILYHERRERA Thank you so much. I placed my order today... tick tock tick tock. Waiting for Amazon on Wednesday ⏳ sigh... 😉

  • @elliedesign8352
    @elliedesign8352 Рік тому

    Thank you for another helpful video. Would you please do a video about the molecular weights of various skin product ingredients, which ones penetrate easily and deeply?

  • @martycollection
    @martycollection Рік тому

    Just yesterday I bought The Essence by Tatcha before applying my Argireline and Matrixyl which is suppose to improve the function of any topical oils or creams applied in order to effect the deeper layers of the skin to create the desired effect.

  • @flucheaux
    @flucheaux Рік тому +117

    I started using Victoria Principal’s skin care line when I was about 32. She later introduced a line called Reclaim that contains Argireline when I was about 40, and I have been using it ever since. I am 61 now, and people tell me I look like I’m in my 40’s.

    • @Pakistankikhana
      @Pakistankikhana Рік тому +1

      Can u tell full product lust plz

    • @phina8392
      @phina8392 Рік тому +9

      Victorias skin care is amazing, she was one of the first to put Argireline in her products years ago, I’m also a fan of her skin care..

    • @cubbyoharaclose4562
      @cubbyoharaclose4562 Рік тому +5

      I came across Victoria Principal in a movie yesterday which jolted my memory of using her Principal Secret skincare many years ago. Based on Agireline. And here is Dr Dray telling us of its benefits. It's a must by the sounds of it.

    • @PassionPno
      @PassionPno Рік тому +7

      Please attach photographic evidence.

    • @apriltumey3230
      @apriltumey3230 Рік тому +1

      I used this in my early 20's and my gosh my face was soooooooooo soft . I loved reclaim! I quit using it because I had 2 lil ones and couldn't pay that.

  • @hannahcourie1826
    @hannahcourie1826 Рік тому +4

    How would you recommend using this in a skin care routine? Morning and night? Before or after tretinoin?

  • @Eteraz
    @Eteraz Рік тому +1

    you made another video a few months ago about this. I saw it about 5 days after I bought Argireline (the Ordinary) and decided to return it but waited so long that it was too late. I started using it on my forehead and around my eye . I was not expecting anything as I had seen your video a few days after buying it. I guess it made my skin a bit better but nothing else. no effect. I'm just using it until it ends and then I'm done.

  • @jojomojo6569
    @jojomojo6569 Рік тому

    You are looking very healthy and glowing. Also, good job on this video!

  • @melanie-rosannastevens7861
    @melanie-rosannastevens7861 Рік тому +2

    Thank you for covering argireline Dr Dray!
    What is your professional opinion on spilanthol? What does the science say so far :D? AFAIK it's also supposed to have a similar effect to botox, as it's a mild topical muscle relaxant

    • @db-gb5xi
      @db-gb5xi Рік тому

      Maybe check out her video, kate middleton's anti-aging serum is botox in a bottle?

  • @michellemalla4365
    @michellemalla4365 Рік тому +5

    Not sure of the science, but since using, i am no longer seeing the line between my brows, those at the mouth still there, but APPEARS to be a little less visible

  • @ashlynnvalana8703
    @ashlynnvalana8703 Рік тому

    Appreciate the info as always!

  • @pinkconfessions
    @pinkconfessions Рік тому

    Your videos are incredibly informative and insightful, in my opinion. I've viewed a lot of your vids. Additionally, you have numerous videos of various and informative skincare products. I don't know which skincare products are best for my skin, and I'm confused.

  • @Hopeapotheke
    @Hopeapotheke Рік тому +6

    I used Botox and it was just so expensive to keep up that I quit. I bought this stuff and I honestly couldn’t see a difference. Now their Matrixyl 10% HA is amazing lol

  • @lindajames5065
    @lindajames5065 Рік тому +1

    Thank you for the information 👍🏻
    Texas Lady🤗

  • @leeboriack8054
    @leeboriack8054 Рік тому

    Dr. Drey, you look great!

  • @mcviky30
    @mcviky30 Рік тому +15

    Great! While in Morocco I used Prickly Pear seeds Oil and I was told that is the natural Botox as Cactus' oil has a kind of paralyzer effect. Could you please tell me more about it? I personally used it for 6 months and it indeed seemed to be kinda paralysing my 11 lines making it smoother. Would it be possible sharing your knowledge in regards? Thanks in advance

  • @EnvyBlu
    @EnvyBlu Рік тому +97

    I use Argireline from The Ordinary and I swear I can feel my forehead relaxing. I actually love the feeling when it does it. And I can absolutely, definitely, tell a difference in my forehead wrinkles. They are reduced quite a bit

    • @theresaholman4199
      @theresaholman4199 Рік тому +6

      Me too. Love it!!!

    • @RukhShariq
      @RukhShariq Рік тому +3

      I will try, thanks for sharing.

    • @foxytroy
      @foxytroy Рік тому +7

      Dr Dray said at the very least it's a good humectant. HA is also a humectant and works similarly in improving fine lines by pulling water into the surface of the skin and is known to penetrate depending on how big the molecules are. I stuck with HA and retinols.

    • @amysquie
      @amysquie Рік тому +8

      I think I'm gonna have to try it, and if they can bring out a serum that would relax my jaw as well I'd be all over it!

    • @kingal.4575
      @kingal.4575 Рік тому

      Same, although I use different brands.

  • @dinapawlow1622
    @dinapawlow1622 Рік тому +1

    Thanks, excellent explanation. My problem with vit c is , is it getting through? And now argireline, is it getting through? Not sure, should I spend on a product that just sits on top and washes off ? Your postings help by highlighting possible scientific limitations to products and their claims.

  • @wisherz
    @wisherz Рік тому +2

    what the heck!!! its vey well explained... thanks doc

  • @soniak2269
    @soniak2269 Рік тому +40

    I have been using argeriline for a few weeks now twice a day on my 11 lines, forehead and crows feet. It certainly has not acted exactly like botox and I would never expect it to work nearly as well as botox. I will say I notice a slight numb feeling for a few hours after applying and overall it is a little more difficult to furrow my brows a few
    Hours after use. Is it in my head? Who knows 😂 but I have already noticed a noticeable difference in my expression lines. Whatever the mechanism of action, I enjoy the result and will keep using it.

    • @poppyseed5270
      @poppyseed5270 Рік тому +2

      The numbing feeling is in your head, the product doesn't have numbing ingredients. Tingling, maybe, but not numbing. She literally just explained how that isn't possible with this product...

    • @SILVEto
      @SILVEto 11 місяців тому

      I know exactly what you mean. It’s not a numbing feeling for me but I feel like it’s certainly making it harder to make those faces. I feel it immediately.

    • @KAFaye-nk5tl
      @KAFaye-nk5tl 6 місяців тому

      which brand of it do you use? 😮

  • @susmitadey7642
    @susmitadey7642 Рік тому +3

    @Dr Dray it would be very informative if we get to know in detail about Clobetasol Propionate and Salicylic Acid ointment. What are long-term and short-term side effects.

    • @db-gb5xi
      @db-gb5xi Рік тому +1

      Is that something found in the US?

    • @Abcdefghiiiiii
      @Abcdefghiiiiii Рік тому

      This is a potent steroid that I use to treat sebborhic dermatitis. And only on my scalp, never heard of anyone using it for their face? You also need a prescription and shouldn’t use unless a dermatologist prescribes it. Short term side effects are stinging - although it shouldn’t hurt too bad. And long term, you shouldn’t use it for an extended period of time because overuse results in skin thinning or atrophy.

  • @cassandrasmith4838
    @cassandrasmith4838 Рік тому +1

    Your skin looks so good.

  • @rosalindd1386
    @rosalindd1386 4 місяці тому

    Thank you Dr Dray !

  • @kirsten121
    @kirsten121 Рік тому +3

    I like where you pitch your videos - for intelligent people who want to spend their time and money wisely! Not for silly girls who fall for marketing and snake oil. I love knowing all the science - I feel like Amy Farrah-Fowler!

  • @priscillapie
    @priscillapie Рік тому +66

    I’m halfway through my first bottle of Argireline and I’m noticing less fine lines on my forehead ! Excited to see more results.

    • @KJB0001
      @KJB0001 Рік тому +7

      Priscilla, update us in another 90 days!!!

    • @joanndr
      @joanndr Рік тому +1

      Do you apply it located or all over your face?

    • @myselfme7945
      @myselfme7945 Рік тому +9

      Don't text the account that says u won something, it looks like a scam

    • @thelizardkween
      @thelizardkween Рік тому +1

      @@myselfme7945 lmao no shit

    • @MrNordicnicklas
      @MrNordicnicklas 8 місяців тому +2

      How about now?

  • @kerrsmith9195
    @kerrsmith9195 7 місяців тому +1

    I have been using The Ordinary Argireline for a year now and have seen fabulous results, especially when it came to the softening of the lines (not fine lines, LINES or WRINKLES) on my forehead.

  • @Levelheads4421
    @Levelheads4421 Рік тому

    Hi Dr. Dray - I saw an ad on here where you were promoting the iRestore hair growth machine.. can you do a video on that? I trust your word, so I’m curious about your thoughts on it in more detail.
    Thanks!!

  • @sandyschultz4763
    @sandyschultz4763 Рік тому +2

    Love your videos! Question! I know in previous videos you mentioned Botox could help reduce acne. Could this product potentially work the same as Botox would in that effect?