Factor V Leiden - Hypercoagulability - Bleeding and Coagulation Disorders - Hematology

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  • Опубліковано 2 сер 2024
  • Factor V Leiden is a genetic disease characterized by a mutant factor V which resists inactivation by Activated Protein C (APC). Factor V leiden is the most common inherited disease of hypercoagulability. Patients with Factor V Leiden suffer from increased risk of thrombosis especially venous thromboembolism (VTE).
    Hypofibrinogenemia and Hypoprothrombinemia...Coagulation Disorders.
    Coagulation Tests (PT, aPTT, TT, Fibrinogen, Mixing Studies,..etc).
    The coagulation factors are divided into 3 coagulation groups | Fibrinogen group, Prothrombin group, and Contact Group..
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    Platelet count is one of the lab tests used by a doctor or a hematologist to assess whether your platelet number is normal, low (thrombocytopenia) or high (thrombocytosis).
    Bleeding 🩸 time (BT) is another test for platelet function.
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КОМЕНТАРІ • 79

  • @mannshah518
    @mannshah518 4 роки тому +27

    This channel needs more recognition. These vids are so informative but they aren't boring. Thanks for keeping our interest in medicine at a high during this pandemic. ♥

  • @sarahbradford1647
    @sarahbradford1647 3 роки тому +10

    can’t believe this is the first time I’ve found your channel! the voiceover is hilarious and your teaching style is so complementary to my learning style. thank you!!

  • @mari4sol
    @mari4sol 3 роки тому +2

    hi doc I just saw the video, I have Factor V Leiden - and was concerned about the corona vaccine, the subject is very complex but fantastic and easy to unterstand by you , thank you a Nurse from Germany

  • @yinkus100
    @yinkus100 4 роки тому +5

    oh medicosis, always on point! I always carry my bottle of vit D everywhere because I am a classical example of the Nigerian girl who migrated to Northern Alberta!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 роки тому +1

      I wish you all the best!
      You’re such a great person!
      Thank you so much for supporting my channel!

  • @user-sw6hl1dd2x
    @user-sw6hl1dd2x 11 місяців тому +2

    I can't prescribe my happiness that l understood this topic.. Thank u so much..

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  11 місяців тому +1

      You're very welcome!
      Would you please help me by sharing my videos with others?

  • @roll96shreyashimukherjee32
    @roll96shreyashimukherjee32 4 роки тому +3

    Highly indebted to you for all these videos. Thank you ❤

  • @BrianaKozak
    @BrianaKozak 2 роки тому +2

    You made me understand something I never thought I could and it was entertaining. Love it!

  • @manarsmaan2624
    @manarsmaan2624 2 роки тому +1

    The Greatest way of teaching. Thank you

  • @annielawrence2985
    @annielawrence2985 4 роки тому +2

    You are so fun🤩...keep doing these sir😊

  • @annalese6448
    @annalese6448 2 роки тому

    love your vids! Hilarious and on point

  • @roll96shreyashimukherjee32
    @roll96shreyashimukherjee32 4 роки тому

    Dr ,you're the best!!!!!

  • @laurensullivan1522
    @laurensullivan1522 3 роки тому

    Brilliant! Thank you sir!

  • @rigaleb
    @rigaleb 2 роки тому +2

    What can you say about the novel Factor XI inhibitors, like abelacimab? Would it be more efficient than factor Xa inhibitors considering it has a considerable lower bleeding risk and apprent higher efficiency compared to enoxaparin? They say it's the holy grail of anticoagulation since it virtually eliminates the risk of excessive bleeding while at the same slowing the intrinsic coagulation pathway.

  • @malanglog138
    @malanglog138 Рік тому

    wao lub you ho gya

  • @bahiachibi895
    @bahiachibi895 11 місяців тому

    Thanks 😊

  • @alanothman4576
    @alanothman4576 10 місяців тому

    you are amazing

  • @jag12341976
    @jag12341976 3 роки тому +1

    Philos means friend, fili means kiss!!!! Agapi is loveeeee!!!!

  • @WolfTeamDirTpride
    @WolfTeamDirTpride 4 роки тому +3

    Damn, i just had Hematology exam today morning and i searched up if you have Factor V mutation but you didn't haha. I was early 1 day 🤣

  • @farihatilat7866
    @farihatilat7866 Рік тому +1

    Very helpful....... Respect sir❤️❤️

  • @meenabarot2037
    @meenabarot2037 Рік тому +1

    awesome!!

  • @debbieseiffertbuildingdepa4883
    @debbieseiffertbuildingdepa4883 4 роки тому +1

    So I have been told I have Leiden Factor V -doubled? Found out after having my third child. I am 55 now and using cayenne and hot spices to thin my blood. I've been to hematologist here in Vegas and frankly, they didn't seem too interested in helping me, not sure why. I like to get messages especially on my legs, they always feel tight. I am wondering if it's a good idea to have massages if it loosens up the vein and can cause clots? I feel like I have very minimal circulation in my legs. I am not a student or doctor and your video is very helpful but I am still a little confused as to what to do next if there's a way to thin the blood without getting stuck on drugs for the rest of my life ( which seems to lessen the life span of peoples lives considerably I've noticed) people I know not on prescription drugs live longer than the ones on prescription drugs. An excellent video I will watch again as I am really trying to understand this, and interestingly enough I was raised to think I was 50% French and 50% German, found out I am 50% Irish/Scottish and not too much french and german as I thought (but this is from ancestry.com so who knows how accurate that is?)

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 роки тому +6

      Hey Debbie,
      How are you?
      I am so s you’re going through this.
      Using cayenne and hot spices to thin your blood is not scientifically proven. Moreover, it’s almost impossible to calculate the dose. In addition, you need some lab tests to tell you how bad the problem is.
      When you said: “People who are not on prescription drugs live longer”...How do you know? What hard evidence do you have? And what do you mean by “people”, or what type of “drugs”???!
      Also, I’ve never heard of Leiden Factor V- “doubled”...If I were you, I would see another hematologist....Look, it took me a long time to find the right mechanic. Finding the right hematologist is not going to be easy. Keep looking and don’t give up. I know a lot about medicine, but I will never treat myself if I had Factor V Leiden...I need a specialist who does that for a living!
      Take care!
      I wish you the best!

    • @asamanyworlds3772
      @asamanyworlds3772 3 роки тому +1

      Same here

    • @opalfishsparklequasar8663
      @opalfishsparklequasar8663 Рік тому

      A "double dose" of FVL
      may mean you have
      TWO copies of the gene
      (which is autosomal dominant),
      which puts you at an
      EXTREMELY higher risk
      for blood clots.
      Anticoagulant therapy is
      LIFESAVING.

  • @user-gw5pb3bq8e
    @user-gw5pb3bq8e 6 місяців тому

    Thank you very much for this wonderful explanation. I hope you enjoy this beautiful explanation 🪻❤️ Please, how can I get the pdf please?

  • @stvnchrist
    @stvnchrist 3 роки тому +2

    There are few caucasians that were born and raised in Nigeria, but I got the point🤓”There are no solutions, just trade offs”

  • @ThatsWhy-
    @ThatsWhy- 3 роки тому

    What is meant specifically by blood stasis here in this triad, please? Is it the thrombocytosis "platelet counts"? Or velocity vs viscosity syndrome??

  • @mhuraic
    @mhuraic 3 роки тому

    "In a place where the sun does shine" 😄 you're very funny

  • @marlenescottie970
    @marlenescottie970 5 місяців тому

    Diagnosed Sept 2023

  • @Yousefmmohammed
    @Yousefmmohammed 4 роки тому

    What application do u use to make these animated notes???

  • @FireFly-ew9rp
    @FireFly-ew9rp 3 роки тому

    Hey medicosis perfectionalist ! How many hours do u study ? Send us ur routine .I am exhausted.Need it for motivation.😂

  • @DjoleeeSD
    @DjoleeeSD Рік тому +1

    "only pink you are going to see is under microscope" ahahahahaha :D

  • @VickyGoss
    @VickyGoss 2 місяці тому

    What if G1691 is Present ( Factor V Normal Alelle G1691

  • @Full_monty
    @Full_monty 3 роки тому

    What about someone who's considering trt with Factor 5

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 роки тому

      What about them?

    • @Full_monty
      @Full_monty 3 роки тому

      @@MedicosisPerfectionalis wouldn't trt increase the chances of developing a blood clot?
      I have Factor 5

  • @zakiyare885
    @zakiyare885 11 місяців тому

    They have Thrombosis

  • @YT_watcher7385
    @YT_watcher7385 2 місяці тому

    I watch these videos simply to hear his annunciation of medications

  • @slycoffy
    @slycoffy 3 роки тому

    Do you have a medical speciality?

  • @mohama2018
    @mohama2018 2 роки тому

    Messi looks funny 😆

  • @amalRay23
    @amalRay23 2 роки тому +1

    I FKN LUV U

  • @asamanyworlds3772
    @asamanyworlds3772 3 роки тому

    I found out I got it I had twelve blood clots

  • @BieberGirl474
    @BieberGirl474 Рік тому

    Why did you shit on family doctors like that lol

  • @LinaAlSelek
    @LinaAlSelek 4 роки тому

    Too fast in your explanation

  • @dr.noir27
    @dr.noir27 2 роки тому

    why change the voice? what’s up with attitude!