Could a drug prevent depression and PTSD? | Rebecca Brachman

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  • Опубліковано 12 січ 2017
  • The path to better medicine is paved with accidental yet revolutionary discoveries. In this well-told tale of how science happens, neuroscientist Rebecca Brachman shares news of a serendipitous breakthrough treatment that may prevent mental disorders like depression and PTSD from ever developing. And listen for an unexpected - and controversial - twist.
    TEDTalks is a daily video podcast of the best talks and performances from the TED Conference, where the world's leading thinkers and doers give the talk of their lives in 18 minutes (or less). Look for talks on Technology, Entertainment and Design -- plus science, business, global issues, the arts and much more.
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  • Наука та технологія

КОМЕНТАРІ • 544

  • @joelzimmerman8787
    @joelzimmerman8787 5 років тому +128

    PLEASE do whatever it takes to make this medication available to the public. I'll simply say that my life depends on it. I'm not able to do 90% of the things I want in life I just cant do. I hope someone hears me. Thank you for your work to help people in my condition.

    • @erins.5420
      @erins.5420 4 роки тому +5

      I hear you and this drug is being offered for treatment in Phoenix AZ. Not sure if you have it regularly available to you now being a year after you posted your comment but I wish you the very best.

    • @a.k.4085
      @a.k.4085 3 роки тому +1

      @@erins.5420 I believe it is available in other areas now.

    • @codyhughes1147
      @codyhughes1147 3 роки тому +3

      @@a.k.4085 i mean...its available if youre willing to do it illegally...clinics charge you way more than they should. The cost for treatment is a joke.

    • @mrsjonesgoodwill3648
      @mrsjonesgoodwill3648 3 роки тому +2

      I was going through depression and Anxiety, I also have mental problem, for 6 years and a friend of mine introduce me to a herbalist man called Igodo that give me herbal supplement which I took to get ride of it, now I am fine leaving a normal life with my family...
      Contact Igodo (igodospiritualarena@gmail.com) Or call +2348117886076 today if you are still passing through this same issues of life....... Dr Igodo also have cure for..
      Headache pain.
      Stomach pain.
      Cancer.
      Herpes.
      Diabetes.
      BP problems.
      HIV... And many more cure for so many sickness cure with his herbal medicine..

    • @PeaceLoveUnityRespect
      @PeaceLoveUnityRespect Рік тому

      Talk to your doctor today about Spravato, an FDA-approved form of Ketamine (Esketamine - specific isomer or "form" of ketamine) nasal spray to TREAT depression symptoms after only a few sessions!!! No more daily pill(s) and high medical bills! Truly life changing! Disclosure: I do not work for Johnson & Johnson, the owners of the drug. I am commenting on personal experience after spending years on Zoloft, Cymbalta, Seroquel, Xanax, and Dexedrine and being able to stop all together after 4 sessions of Spravato.

  • @aylawestfall703
    @aylawestfall703 7 років тому +43

    The only problem with preventing a disease/disorder entirely is that there is no money in a cure. Why is chemotherapy is still a major cancer treatment? It can cure, or it can extend a life, but the person suffering is continues paying the medical bills for the continuation of the medication. There's lots of money in treatment, but there's no money in a cure. Which is incredibly sad.

  • @pattihawks8514
    @pattihawks8514 4 роки тому +35

    I would love to be “inappropriately happy” for a change! I pray this drug gets
    approval!

    • @michaelleahy123
      @michaelleahy123 3 роки тому +5

      its here

    • @cristianhernandez3099
      @cristianhernandez3099 2 роки тому +2

      This was me before I started taking ANY medication. Specially after the 20mg x 3 a day that the moron doctor later said people "drug deal with"... People used to asked me why was I smiling all the time... that is I was high on Cannabis? lol no... the real question is why are you not smiling all the time... well because no matter how much medicine/drugs we consume... that is not the key to happiness. How did happy become something inappropriate?

  • @rez4998
    @rez4998 4 роки тому +54

    I recently started ketamine for mental health and it has changed my LIFE. This talk was very well articulated thank you

    • @haha-kk8mo
      @haha-kk8mo 4 роки тому +2

      Really? Can u explain a little more

    • @sais8681
      @sais8681 4 роки тому +2

      I wish the treatment was available in India.

    • @justis00
      @justis00 4 роки тому +2

      @@sais8681 It is!

    • @PeysonPhillips
      @PeysonPhillips 3 роки тому +6

      Same for me! Miracle treatment after years and years of antidepressants and talk therapy! Ketamine clinics are popping up all over now after 2020. Research for the best clinic and doctor in your area! I would have never guessed there were 5 clinics super close to me in Dallas,Texas!

    • @RedLP5000S
      @RedLP5000S 3 роки тому +5

      I wish to god that Ketamine infusions were FDA approved. I cannot afford the cost. I desperately need this treatment. I feel suicidal all the time.

  • @erins.5420
    @erins.5420 4 роки тому +10

    Now it makes sense, my recreational use of Special K in my later teenage years were difficult and I wondered why I wasn’t messed up for life from the experiences that some of my other friends through the year have been affected.

  • @rebekkad.2092
    @rebekkad.2092 4 роки тому +4

    Excellent information. One of the best talks I've heard.

  • @arielsabrinadre2237
    @arielsabrinadre2237 2 роки тому +9

    I’m up late anxious about my appointment tomorrow to talk with a doctor about this therapy. It really helped me to hear this tonight. Thank you.

    • @ChristisKing7922
      @ChristisKing7922 2 роки тому +3

      How did it go for you? I had my consultation just a couple hours ago and I’m excited, but very nervous lol

    • @desertrose9063
      @desertrose9063 2 роки тому +2

      Me too. 5 days until my 1st ketamine infusion. 💜

    • @arielsabrinadre2237
      @arielsabrinadre2237 Рік тому +1

      I forgot that I left this comment, revisiting this video a year later. This drug changed my life. I can’t stop crying listening to this because of how impactful it was

  • @ivanbarreras9445
    @ivanbarreras9445 7 років тому +70

    isn't microdosing psilocybin proving to be great at treating depression and ptsd?

    • @AnonEyeMouse
      @AnonEyeMouse 7 років тому +1

      Ivan Barreras Too early to tell. But that isn't a no...

    • @ivanbarreras9445
      @ivanbarreras9445 7 років тому +5

      I've heard a single usage is helpful, but only up to three months. Although I read that for depression and people trying to quit smoking. And in it they mention ptsd.

    • @86Dynamix
      @86Dynamix 7 років тому +10

      Didn't work for me as an anti depressant and I've done it for months. A good dose of mushrooms did alleviate my depression for months though.

    • @ivanbarreras9445
      @ivanbarreras9445 7 років тому +2

      so the microdosing didnt work, but a single, or a few higher doses spread apart did? that is interesting. I believe the review i read mentioned higher doses, so about the equivalent of a gram of dried mushrooms (pretty light) had noticable effects up to three months time. Did that also occur with you?

    • @Gelamine
      @Gelamine 7 років тому +15

      5g in silent darkness, face your demons, die & resurrect

  • @kimberlyrice4294
    @kimberlyrice4294 5 років тому +8

    They used Ketamine via IV on me three separate times in the ER for severe migraine pain and compared to most options it was fairly effective.
    You have to keep in mind that by the time the pain is severe enough to take me to the ER my options are somewhat limited as the pain and other symptoms are so far out of control.
    I’ve been considering investigating it to combat my major depression now.
    As for my share of pain; I think I’ve given enough.

    • @sachchidanandchaudhary1629
      @sachchidanandchaudhary1629 3 роки тому +1

      U can take deeptms with ketamine and ssri these will have synergistic effect and also you can start using tdcs device . Hit gym it will also help u a lot do high intensity interval training

  • @4tech69
    @4tech69 7 років тому +59

    Interesting. The majority of mental illness is actuality triggered by external conflict. I.E A symptom of the socio-ecological existence we have created and are bound to. We should focus on both, the medical treatment and possible paravaccine science. We should also work to change the socio-ecological model that we live in to one that is less damaging as a whole.

    • @j.rising7286
      @j.rising7286 7 років тому

      4tech69 💯

    • @loubensjanvier3364
      @loubensjanvier3364 7 років тому

      4tech69

    • @maxybaer123
      @maxybaer123 7 років тому +1

      not an expert but im pretty sure that's not true or at least misleading a large part of mental illness is caused by trauma or at birth and it can be cured or worked around by using medication or psychologists

    • @AnonEyeMouse
      @AnonEyeMouse 7 років тому +4

      maxybaer123 My glib response above, aside... The truth is that most mental illness is due to a developmental issue. All children are blank mental slates with genetic factors making them more or less prone to different mental factors. Good and Bad, from our perspective. It is the work of the parent, the teacher and society as a whole to train children to become well rounded human beings. Mental health tends to screw up when some aspect is missed in a child's development or is over emphasised. We've all got minor neurosise thanks to this, often it isn't a major problem. However the more pronounced cases produce adults with widely unhealthy mental landscapes (for our culture). That isn't necessarily due to trauma, but merely that something was missed. over state the difference between right and wrong as a parent and your kid can grow up depressed or excessively angry, with no real way of coping with nuence or moral ambiguity. Understate it and you may get a sociopath. No trauma required.

    • @AnonEyeMouse
      @AnonEyeMouse 7 років тому +1

      maxybaer123 My glib response above, aside... The truth is that most mental illness is due to a developmental issue. All children are blank mental slates with genetic factors making them more or less prone to different mental factors. Good and Bad, from our perspective. It is the work of the parent, the teacher and society as a whole to train children to become well rounded human beings. Mental health tends to screw up when some aspect is missed in a child's development or is over emphasised. We've all got minor neurosise thanks to this, often it isn't a major problem. However the more pronounced cases produce adults with widely unhealthy mental landscapes (for our culture). That isn't necessarily due to trauma, but merely that something was missed. over state the difference between right and wrong as a parent and your kid can grow up depressed or excessively angry, with no real way of coping with nuence or moral ambiguity. Understate it and you may get a sociopath. No trauma required.

  • @06livefast
    @06livefast 7 років тому +83

    Yes, it's called mdma.

    • @Dakotaidk
      @Dakotaidk 7 років тому

      mmm meth

    • @Dakotaidk
      @Dakotaidk 7 років тому

      Zachary Williams it's literally the same drug dumbass

    • @Dakotaidk
      @Dakotaidk 7 років тому +1

      Zachary Williams MethylenedioxyMETHAMPHETEMINE

    • @Chocolateleg0Ofcl
      @Chocolateleg0Ofcl 7 років тому +6

      Lol if you knew 1 thing about chemistry then you'd know that just because the name of something else is in there doesn't mean its the same thing - see the METHYLENEDIOXY bit?

    • @Dakotaidk
      @Dakotaidk 7 років тому

      Equinox mdma is synthesized from meth bro
      Do research?

  • @ryangraham1234
    @ryangraham1234 7 років тому +2

    Great TED Talk! Well done and well said...

  • @user-ii1yw6wo7m
    @user-ii1yw6wo7m 7 років тому +27

    I have suffered from depression from the last ten years, its totally paralyze you, being mentally paralyze is worse than physically paralyzed, you become emotionally & spiritually dead, you suffer, your love ones also suffer with you, I wish treatment for depression should be discovered as soon as possible, waiting for miracle!!!

    • @user-ii1yw6wo7m
      @user-ii1yw6wo7m 7 років тому +7

      US President Abraham Lincoln & British Prime minister Winston Churchill also suffered from depression in their lives, Winston Churchill used to call depression "BLACK DOG", of his life, makes a normal Happy person sad any moment, he learned to live with this black dog all his life!!!

    • @jredenfield
      @jredenfield 5 років тому +4

      Find a qualified clinic that does Theta Burst Stimulation and Ketamine Injections. TBS saved my life, literally...

    • @gelbusherpa1947
      @gelbusherpa1947 4 роки тому

      I am in that state right now ☹️ ..

    • @pattihawks8514
      @pattihawks8514 4 роки тому +1

      1
      In addition to depression, I have physical disablement and chronic pain. The depression is sometimes thought to be worse than the pain!

    • @eileendoherty2836
      @eileendoherty2836 4 роки тому

      Jay Edenfield hi jay do u have to pay for ketamine and theta burst ???

  • @lissaajz
    @lissaajz 5 років тому +6

    What an AMAZING TED regardless of personal opinions (I’m wise therefore haven’t made my own yet) on the subject!!! Awesome job!!! 👏🏻👏🏻👏🏻👏🏻

  • @harness84_29
    @harness84_29 7 років тому +24

    MDMA helped me talk about my issues when i was younger. it worked great. the world is so closed minded when it comes to drugs and their true power. i have never heard of anyone going out on the town and getting into a fight on MDMA, but alcohol which is legal everywhere causes drink driving,domestic violence and deaths everywhere......such a great society we live in

    • @hot_salsa_dipping_sauce
      @hot_salsa_dipping_sauce 2 роки тому +7

      I feel like mdma helped me with my anxiety. It wasn't too bad, I would say it was mild. I don't do mdma that often and I don't do high doses either. It's been a year since I first tried it and those few times I experimented with it made quite the difference. I became more sociable and I don't find it awkward to interact with other people anymore and most importanly I'm having fun now, I can enjoy life.

    • @scres87
      @scres87 2 роки тому +2

      @@hot_salsa_dipping_sauce thank you for sharing this anecdote. I recently tried a low dose for my first time and it was incredible like a night and day difference.
      I want to start taking it more regularly while still spacing it out by a few months, but I feel like this will be a huge help. Fingers crossed.

    • @bobjary9382
      @bobjary9382 5 місяців тому

      Lsd mdma pot and speed all helped me . They all gave me a bumpy ride but weighing things up their effect overall was good.
      Ketamine ssris benzos never did a thing other than make me feel disgusting.
      Horses for courses

  • @KCOLBURN_8
    @KCOLBURN_8 2 роки тому +1

    I go for my first consultation tomorrow. Nervous but excited. OCD has controlled my life for too long.

  • @nelsonsantiago2514
    @nelsonsantiago2514 4 роки тому

    Thank you for doing what you do.

  • @FizzyMcPhysics
    @FizzyMcPhysics 7 років тому +11

    I love that 3 of the top 4 posts on this thread are jokes about the drug being a recreational drug "Yes, it's called mdma", "It's called Weed", "yes its called lsd".
    Well the joke's on them because if any of them had actually watched this video to the end then they'd know that the twist is it's actually called Special K!

  • @inyerd123
    @inyerd123 7 років тому +118

    yes its called lsd

    • @inyerd123
      @inyerd123 7 років тому +17

      well LSD wouldn't prevent, but can treat it, as well as mushrooms and mdma

    • @kasnitch
      @kasnitch 7 років тому +8

      and ketamine in low doses with virtually 0 side effects

    • @DeoMachina
      @DeoMachina 7 років тому +8

      People with PTSD and depression do still need to be able to do things with their life though, the problem with recreational drugs is that you're essentially useless until it wears off.

    • @AnonEyeMouse
      @AnonEyeMouse 7 років тому +3

      DeoMachina That comes down to dosage and refinement. There are treatments developed using cannabis that have zero chance of getting you stoned, because the part that has a particular medical benefit can be isolated from the recreational effect.
      I know that LSD has shown to have benefits for depression in small enough doses not to cause functional impairment.

    • @QueenShiva1920
      @QueenShiva1920 7 років тому +4

      DeoMachina I would agree but at this point the MDMA that is being tested isn't for recreational use. It's safely administered by a medical professional while the participant is undergoing therapy. It will be very interesting to see the results.

  • @FancyThatBumNow
    @FancyThatBumNow 7 років тому +6

    15:50 what a twist! great talk :)

  • @sheffair1
    @sheffair1 7 років тому +2

    Great talk - very interesting 👍

  • @realfishtacoboy
    @realfishtacoboy 7 років тому +46

    I have crippling depression!

    • @AnonEyeMouse
      @AnonEyeMouse 7 років тому

      Peter the Porcupine As do I. Nothing here for us, however.

    • @86Dynamix
      @86Dynamix 7 років тому +7

      Mushrooms worked for me as well. Depression free for months..

    • @FreeBird9001
      @FreeBird9001 7 років тому +3

      I have osteoporosis

    • @leeleeturn
      @leeleeturn 7 років тому

      Yves Paradis Well I don't have any clue how to get them, unfortunately, so I guess I'll never get to find out.

    • @realfishtacoboy
      @realfishtacoboy 7 років тому

      Carlton Banks lol

  • @kaylamichellee
    @kaylamichellee 2 роки тому +4

    I signed up for my first Ketamine infusions. I will update when I try it to let you know how I feel. I have severe compound-complex PTSD, I’m praying did a miracle💔❤️

    • @ChristisKing7922
      @ChristisKing7922 2 роки тому +2

      Excited for you!!!

    • @clipp7777
      @clipp7777 2 роки тому +1

      Praying for you. Please let us know how it worked for you....😔🙏🕯️

    • @jessicadeleon9477
      @jessicadeleon9477 2 роки тому +3

      How did it go?

    • @slsp9008
      @slsp9008 2 роки тому +2

      Update plz!!

    • @gr8dvd
      @gr8dvd Рік тому

      RIP.
      Or, if doing well, great/congrats! If able to update, no matter the outcome (good/bad/canceled appointment-why)… would be much appreciated. Hope my dark humor isn’t off-putting and your doing well.

  • @EleniEliades_
    @EleniEliades_ 5 років тому +7

    Ketamine drips are very expensive, insurance coverage is not available. I was offered to try it however, I declined. It lasts a week to two then you have to go back and get another
    Ketamine drip { they play music as you lay back in a cushioned chair in the dark } as it takes 20 minutes. Sometimes it doesn't even work, unfortunately you still get charged. It is
    just too expensive for me $275 - $350 every two weeks.

    • @sachchidanandchaudhary1629
      @sachchidanandchaudhary1629 3 роки тому +1

      Here in India i buy ketamine vile which will be used for 10 infusion @$14 .....only u can give me your address i will send you ketamine at this price only from india if it helps you .,...india is the biggest source of ketamine I buy it from hospitals .....
      And do take that with ssri it will have synergistic effect and if u combine deeptms believe me you will be completely out of depression ...as i am now....only thing i have not tried is (psilocybin,lsd,mdma,etc powerful psydelic)

    • @TimothyAllison1
      @TimothyAllison1 2 роки тому +1

      Ketamine therapy is used along with cognitive therapy. It is not as simple as receiving a ketamine drip while listening to music and magically you are cured. Ketamine is a useful pert of a structured treatment plan. This Ted Talk is spot on, my hat is off to the Dr.

  • @elijahragland8498
    @elijahragland8498 7 років тому +54

    I find it deathly ironic that an antidepressant can make you suicidal.

    • @tyed94
      @tyed94 7 років тому +5

      No anti-depressants don't fix the underlining issue. You literally kill you emotion so you can't feel depressed but usually, you can't feel happy either.
      its a fucked up treatment that only really works with therapy and counseling. because then you get to the underlined problem
      my grandmother has dealt with this for a long time.
      MEO Inhibeter is also a common term for antidepressants it inhibits your MEO receptors.

    • @theUglyManowar
      @theUglyManowar 7 років тому +1

      The ssri's flood the brain like a shotgun approach to hit the target so side effects will vary?

    • @computer5272
      @computer5272 7 років тому +1

      Ty Smith No, you clearly don't even understand what depression is, it doesn't mean your sad, not in the slightest.

    • @vlove6730
      @vlove6730 6 років тому +2

      that is, exactly what it is, my friend. deathly ironic... lol

    • @vlove6730
      @vlove6730 6 років тому

      woow dude. youre probably spot tf on. that makes a lot of sense...

  • @atiqrahman7289
    @atiqrahman7289 Рік тому

    Excellent presentation is this.

  • @dylanstone532
    @dylanstone532 7 років тому +34

    the biggest problem with this video from my point of view is that everyone experiences drugs differently and they always have a different effect even if you have similar trip it's not exactly the same we all experience things differently from our own point of view so this question only really comes down to how you feel about it or how it makes you feel........ and yes they have anti depressants are drugs that make you feel better but I guess that's not completely accurate either because you can also become more depressed

    • @alecsst.7808
      @alecsst.7808 7 років тому +2

      Dylan Stone it is just tested on mice, thats why she said, it COULD be the perfect solution

    • @2CSST2
      @2CSST2 7 років тому +2

      This is not a "trip", the dose used would induce very mild "trippy" effects if any at all. Also of course not everyone respond to same way to them, that's the whole purpose of having statistics on whether or not patients lose their depression symptoms, those numbers are the equivalent to what you say but in a quantitative talking way. "It could or could not work" is obvious but doesn't get you anywhere, "it works on 70% of patients" IS an accurate description of its effect.

    • @auroraloesel2891
      @auroraloesel2891 7 років тому +2

      Dylan, while it is true that some people react to medications differently, that is what side effects are there for because some peoples bodies physiologically work slightly differently than others which is why these side effects happen. Just because a minority of people may have a bad reaction to a medication that could prevent depression and PTSD does not mean research on this medication should stop. This is an act utilitarian perspective because it is focused on bringing about the best outcome in a specific situation. Furthermore, the fact that its active ingredient is ketamine is alarming to some, however, it is already approved by the FDA for other treatments so if it works to cure and prevent depression and PTSD then it is best to keep working with it because it will be able to be prescribed faster.

    • @theUglyManowar
      @theUglyManowar 7 років тому

      She did point out that they were clueless on many issues. And most all education on Anti-depressants point out the horrible success rate as she did.
      So she was hardly disingenuous. Actually pointed out why such alternative avenues are important to the research.

    • @susandarnell4884
      @susandarnell4884 6 років тому +1

      But the street version is more dangerous. And, The effects are tested for generations and are predictable. it might not work t all K-holes are bad, but normal during an adjustment period. patient needs assistance. A partner. with a flow chart. Duh.

  • @FROFilmsIRE
    @FROFilmsIRE 3 роки тому +14

    It frustrates me that researchers are getting famous and speakers like this are getting mass exposure by TALKING about this stuff. Meanwhile we suffer away in silence while these treatments are restricted from us. This is sickening. If something has been found to work, you have a duty to make it available to those suffering needlessly immediately.

    • @MrSandman12566
      @MrSandman12566 Рік тому

      It’s starting to become more available, while still expensive. The way I looked at it, what it would cost for medication over a year compared to the cost of infusion….. it was very close price wise.

  • @stenandersson6704
    @stenandersson6704 4 роки тому +1

    Excellent, time to try out Calypsol!

  • @aratibagal7036
    @aratibagal7036 6 років тому +4

    Well someone who has suffered from depression or is suffering from depression can truly understand the impact it has on life. True potential of a person goes to waste. It is a really debilitating disease. I know how i have transformed from my pre depression days to now. If there is cure for it and not just symptomatic cure..... a cure for the cause of the disease , it in fact would save lives of people. Not only that but it will enable a human being to reach their own potential.

  • @RosethornJMF
    @RosethornJMF 7 років тому +55

    Spoiler alert: I suspected ketamine before I watched the video. I hope this becomes a viable option for treating and not just preventing depression.

    • @rme36
      @rme36 7 років тому

      I thought about MDMA ^^

    • @wienerwoods
      @wienerwoods 6 років тому +5

      Ketamine cured my depression.
      I'm not alone:
      gizmodo.com/ketamine-relieved-suicidal-thoughts-within-hours-in-hos-1821331604

    • @kension333
      @kension333 5 років тому +1

      @@anonanonanon111 Nah, you just gotta know the right people.

    • @Sg4809
      @Sg4809 4 роки тому +1

      @D Wise so how did it do? How are you feeling near a year later? I do hope you're better

    • @madwithhats
      @madwithhats 4 роки тому +1

      @D Wise Yeah, I'm curious. What happened????

  • @davidsweeney111
    @davidsweeney111 7 років тому +7

    Excellent presentation!

    • @name-qv1dp
      @name-qv1dp 7 років тому +2

      It was actually terrible. There were obvious flaws, she went off topic more than once and for up to 2 and half minutes, and she's just promoting another brain killing drug to help big pharmaceuticals make money.

  • @beyondthecircuit
    @beyondthecircuit 2 роки тому

    Thank you.

  • @rnqtn
    @rnqtn 7 років тому +3

    She reminds me of Officer Spivot from Flash.

  • @mr.patriot3992
    @mr.patriot3992 2 роки тому

    Amazing talk

  • @juliaeve
    @juliaeve 7 років тому +4

    Her voice is sure lovely 😊

  • @jopmens6960
    @jopmens6960 7 років тому

    The great promise may be its metabolite dihydroxynorketamine (it's not the exact full name), which I think is not psychoactive in the way ketamine is "primarily", although the antidepressant doses of K needed are also lower than what you would trip from, but if anything it could help with the image connotations, and it seems like a good idea to isolate the AD activity for AD use.

  • @adrianeyre550
    @adrianeyre550 6 років тому +1

    That lady is amazing

  • @61shirley
    @61shirley 7 років тому +11

    Yes, it's called cannabis and it works. Others like MDMA and the psychedelic experience are also highly effective.

  • @austinbradley2922
    @austinbradley2922 7 років тому +1

    perfect!

  • @grahampalmer
    @grahampalmer 7 років тому +10

    Excellent talk.

    • @Cineenvenordquist
      @Cineenvenordquist 7 років тому

      Graham Palmer Enthused and promising, but what does she ask? Business developers? Currencies in FDA monitored production? Where this might have been circular materiel in charged environments?

    • @grahampalmer
      @grahampalmer 7 років тому

      Mmmm. I think she is suggesting that the powers that be, pharmas and govs, need to allow and financialy support more lateral thinking. I don't know what else she is expected to do.

  • @daviddrew7852
    @daviddrew7852 5 років тому +6

    By way of sad irony, this popped up after an Irving Kirsch video explaining the myths and dangers of largely ineffectual but dangerous anti-depressants. This lady moved from cures for real diseases like TB to curative claims in respect of depression. The correlation is dubious.

    • @bobjary9382
      @bobjary9382 5 місяців тому +1

      My route was via David Healys work on the clear and present dangers of ssris. Funny that

  • @Sid-69
    @Sid-69 4 роки тому +2

    17:59 "This could be the beginning of the end of the mental health epidemic" Amen to that

  • @soonny002
    @soonny002 7 років тому +4

    Glutamate is also implicated in the development of dementia. We need to be careful if this doesn't increase the risk of developing dementia. But who knows? More research is needed.

    • @GeneralSorrow
      @GeneralSorrow 5 років тому

      I forget.

    • @dansmith9724
      @dansmith9724 2 роки тому +2

      I think ketamine blocks the effects of too much glutamate

  • @MrJohmag
    @MrJohmag 5 років тому +7

    Thank you! This helped me understand how self medicating k helped me get out of my depression. I hope ppl in the near future gets to take it with a therapist in a better way then I did it.
    Bless 🙏😌

    • @muhammadmoustafa7122
      @muhammadmoustafa7122 5 років тому +1

      please I want to contact you
      send me any contact to you so I can understand how did you make it

    • @oBluePandaO
      @oBluePandaO 4 роки тому +1

      How do u use it? How often?

    • @eileendoherty2836
      @eileendoherty2836 4 роки тому +1

      Muhammad Moustafa yes please share

  • @pearljamin
    @pearljamin 3 роки тому

    I can see it working for a lot of people, but some of us have been breathing trauma since birth. Maybe years into isolation. I’m not sure I’m in here anymore or what I’d have to work with if the treatment worked.

  • @___blaggard999___8
    @___blaggard999___8 5 років тому +7

    I expected to see a lot of just smoke weed comments, I'm glad I don't. Those are the worst type of stoners

  • @JustOneAsbesto
    @JustOneAsbesto 7 років тому +5

    Sure, I can imagine how a dissociative would protect against stress.

  • @richardsbattella9520
    @richardsbattella9520 7 років тому +4

    Ketamin is probably the Prodrug for the antidepressant that metabolizes from it: Hydroxynorketamin

    • @richardsbattella9520
      @richardsbattella9520 7 років тому +1

      It seems that AMPA Rezeptors are more involved in depression than the NMDA Rezeptor wich is affected By Ketamin

  • @sora120592
    @sora120592 7 років тому +43

    If 1 out of 4 experience depression then maybe its not the people Who are sick. Maybe its the system that is sick.

    • @jopmens6960
      @jopmens6960 7 років тому +2

      I'd say it is important to differentiate chronic sadness from depression. Like you suggest, sadness is a healthy response to bad things happening, but the point is that with depression you are sad even with good things happening. In the model of this video, that would be where the mouse has nothing to fear anymore but still won't really come out. You could call that micro-traumatized though I guess. Animal models can be pretty imperfect.

    • @sora120592
      @sora120592 7 років тому +1

      But thats where we need to think in another mindset. If people are told that there condition is cronicle then it becomes cronicle to them. How you persive yourself affects your mental healh on a greater scale. Drugs should be a last resort supplementet with therapy. If you still se yourself as depressed when you take drugs then it is still there when you stop taking them.

    • @theUglyManowar
      @theUglyManowar 7 років тому

      They already know that it's a stress induced Industrial age epidemic. Along with cancer and Diabetes.
      We know that when poverty levels drop that many issues like crime show relief.
      So addressing such stress factors will B great.
      But I liked how she stressed that the problem ends up being chronic for many sufferers!
      40 years for myself ( with a 12 year interim where I thought I was home free )

    • @Xxluvable94xX
      @Xxluvable94xX 5 років тому +1

      Scroto Bagging because they have less doctors, and less money so they can’t go to the doctor. If you get cancer but don’t go to the doctor and don’t get it diagnosed that doesn’t mean you don’t have cancer. It just means it’s not documented.

    • @Xxluvable94xX
      @Xxluvable94xX 5 років тому

      Jonas Karlsen with your logic all we need to do is tell people they don’t have depression, then they’ll see themselves as happy. Telling someone they’re depressed is actually helpful. It gives them the validation that their not crazy, that what they’re feeling is real and they’re not alone.

  • @erdinca.2448
    @erdinca.2448 7 років тому +2

    I just watched the movie "Zulu".
    In context, the title of this talk is kind of disturbing.

  • @annale4730
    @annale4730 Рік тому

    How often are the injections recommended? From my understanding, ketamine benefits often only last a few weeks in many people?

  • @banditpsy
    @banditpsy 7 років тому +2

    Still a lot of hypotheses and unknown long-term consequences. Taking a psychoactive drug as prevention feels also really problematic. But it would definitely be worth to do further study on.

    • @krool1648
      @krool1648 7 років тому +1

      ¸Google doctor Carl Hart.

    • @banditpsy
      @banditpsy 7 років тому

      Thanks for the tip!

  • @sandrastevens4418
    @sandrastevens4418 2 роки тому +2

    I have had Bipolar disorder II most of my life. I have been on just about every anti mania SSRI's and Mood enhancers.
    I am still going from being hypomanic for a week or 2 and then comes the doom for months.
    To the point that you just can't function are suicidal and just lay in bed.
    If this drug works, sign me up. Because I am tired so tired of being sad.

    • @dogpileontherabbit1
      @dogpileontherabbit1 8 місяців тому

      This drug works - absurdly well. I have been a psychopharmacologist for 25 years. It mostly dwarfs its alternatives.

  • @gillenzfluff8380
    @gillenzfluff8380 5 років тому

    What about high serotonin and psychopathy?

  • @Ilamarea
    @Ilamarea 7 років тому +2

    I need to go to a vet.

  • @Jimboom81
    @Jimboom81 7 років тому +1

    Great

  • @brianlarson77
    @brianlarson77 7 років тому +1

    Meditation and self-realization.

  • @charlotteknutsen7262
    @charlotteknutsen7262 3 роки тому +3

    Ketamine infusions didn't help me at all. Even though my doctor has seen good results for some. It's extremely expensive. I just happened to be one of the non responders.

    • @sachchidanandchaudhary1629
      @sachchidanandchaudhary1629 3 роки тому +1

      I take 1 ketamine vile of 10ml for $14 in India ....actual cost of that vile is just$2 and take it with ssri and also take deeptms with that heard deeptms is like free in usa as public health program .. rtms saved me made me completely normal

    • @clipp7777
      @clipp7777 2 роки тому

      What are rtms?

  • @mcgeufer
    @mcgeufer 7 років тому

    Well that´s late. I saw studys about Ketamin as anti depresant about 10 years ago in Europe. Why does it take so long ?

  • @oBluePandaO
    @oBluePandaO 4 роки тому +1

    What about sexual dysfunction after ssri? (pssd) could ketamine help for it? Or does it make it worse

  • @Matthew00049
    @Matthew00049 5 років тому +2

    Talking about Ketamine starts at 8:00. FF to that

  • @fourthreetwo_8378
    @fourthreetwo_8378 5 років тому

    My mom works at a place where they help people get past drugs like a recovery center, and she said Ketamine was a super addictive drug that people were in there for. I have bad anxiety but I’m not going that long 40 year path of ongoing drug addiction and crime for my stupid 15 year old choice wanting to cure my anxiety to socialize more with the world at that time when I can just grow out of it when I’m 16

    • @AllDayEDC
      @AllDayEDC 2 роки тому +1

      You can become dependent on almost any drug if it becomes a daily habit. Like breaking a soda habit. When offered scheduled in a clinic addiction and dependence chances go down. Im an icu nurse and to my knowledge ketamine is one of the safest drugs. Its on the list of essential medicines due to its value in treatments, lower abuse potentials, and very low harm potential. Please whatever you do dont be like me. Im 27. Thought at 20 i could grow out of it as well. 7 years later i wish i had that yome back as a happier me. Do not wait to feel better. Dont rely on time to heal because there are lots of wound that time alone can not heal

  • @whenilookatthesun
    @whenilookatthesun 6 років тому +1

    Fungi- Take nutrients from host more than they give. In a weakend state with no explaination as to what it could be could lead to a stressful state that spirals into depression. As all things do. This is at least what I feel I am experiencing. Especially since I notice that when it feels like I'm treating my dandruff (no room for shame in science) my mood and cognitive ability to make myself feels better impoves. The more severe the dandruff the more difficult it becomes to get out of my depressive state. Sucorro!

    • @BunnyUK
      @BunnyUK 5 років тому +1

      Sarah Barnice - sounds like the Learned Helplessness research. They found in experiments that when some dogs could not escape a stressful situation, they gave up, and in the future, they didn't try to help themselves when they actually could escape. I think it is true, depression is a feeling of defeat, when you can't see a way to win or to change a negative situation.

  • @eSKAone-
    @eSKAone- 7 років тому +2

    The mind is a symphony of thousands of substances and physiological mechanisms. There is no key substance. I don't think drugs are the answer. People need a purpose.

  • @mammamathews
    @mammamathews 4 роки тому +3

    My antidepressants help with my anxiety but not with my depression. I also suffer from ptsd and I really want to try ketamine treatment.

    • @amazingsweet4125
      @amazingsweet4125 4 роки тому

      Melanie Mathews u don’t have to be depressed hunny. i know it’s the negative thoughts that’s making u unhappy but you can seek help through God. i also suffer from disease anxiety and it lead to this, but I will get out of this as soon as i cure the trauma part and go get some medical tests done so i can finally stop worrying every demonic thoughts that pops into my head

    • @christiangraff5236
      @christiangraff5236 4 роки тому

      @@amazingsweet4125 god isnt going to help with misfiring neuro transmitters in your brain. Hate to break it to you. Thats not how this works

    • @driversoflondon5611
      @driversoflondon5611 3 роки тому

      @@christiangraff5236 hi fellow christian, although God might not help biologically, the idea of him helping you through it can certainly help to an psychological extent for some people (Which in turn is kinda biological at its base)

    • @sachchidanandchaudhary1629
      @sachchidanandchaudhary1629 3 роки тому

      Try ketamine with ssri and deeptms ...all will have synergistic effect although i had depression and anxiety disorder not ptsd ....it helped me alot and made me normal

  • @Bc232klm
    @Bc232klm 7 років тому +3

    Yep! Cannabis really is a fantastic plant :)

  • @guitarhero8719
    @guitarhero8719 5 років тому +1

    Yay! Amazing treatment discovered. Can I have some? No. :(

  • @esantanche
    @esantanche 7 років тому +6

    We are the first adults to handle the generation gap through the wholesale drugging of our children. We may be guaranteeing that future generations will be relatively devoid of people who think creatively, raise painful questions, generate productive conflicts, or lead us to new spiritual and political insights.
    - Dorothy Rowe, Beyond Fear
    We regard the medical model as an extremely inappropriate model for dealing with psychological disturbances. The model that makes more sense is a growth model or a developmental model. In other words we see people as having a potential for growth and development and that can be released under the right psychological climate. We don't see them as sick and needing a diagnosis, a prescription and a cure; and that is a very fundamental difference with a good many implications.
    - Carl Rogers
    She says: "we might be able to protect people who are predictably at risk against stress-induced disorders like depression and ptsd" -- what about loving them? what happened to love? We used it to heal the pain of distressed people for thousands of years and it worked!
    Freedom is the best antidepressant in the world. Those who want us to be slaves so that they can exploit us prefer us to take drugs of course instead of giving us freedom.
    Never take these drugs. They are only used to shut us up. If education was based on freedom and absence of fear instead of violence, our childhood would be our antidepressant. It's that the psychotics who rule the world want us scared.

    • @devashishgole4722
      @devashishgole4722 5 років тому

      Emanuele Santanche hmm, interesting ... What do u feel about vaccines?

  • @JonasUllenius
    @JonasUllenius 7 років тому +1

    You say that the cost is trillions dollars is there a way that companies that help prevent this kind of disease can get a little tax deduction?
    Ore like in Germany where they get tree weeks of at a spa to recover if they have symptoms like the ones you discussed?

  • @robroy4137
    @robroy4137 4 роки тому +6

    She’s wearing my pajama top

  • @IDislikeTheNewYoutube
    @IDislikeTheNewYoutube 7 років тому +134

    Now tell us how much you were paid by what pharmaceutical company to give this talk.

    • @euttdsiggh2783
      @euttdsiggh2783 7 років тому +5

      you know how stuff goes...

    • @SystemLordNemo
      @SystemLordNemo 7 років тому +32

      Didn't she say that the drug is generic and not even tested for that? There is no F¤¤&¤ing money in that.

    • @AnonEyeMouse
      @AnonEyeMouse 7 років тому +18

      I Dislike the new UA-cam There would be no profit in it. Ketamine is so cheap to produce, so widely available illegally, and from what she is saying, requires a tiny dosage at incredibly spaced out intervals... No one would make a profit on this. Except, maybe, street dealers. A generics manufacturer could pump out ketamine, it isn't under patent any more...
      It just sucks that it doesn't work on this who already have depression.

    • @DeoMachina
      @DeoMachina 7 років тому +30

      Funny how people are only this skeptical when it comes to medicine

    • @mohammadmohd113
      @mohammadmohd113 7 років тому +4

      Um? ^ This is the extent of the cynicism you've seen/heard?

  • @reenspace1301
    @reenspace1301 7 років тому +3

    anti depression medicines makes you "inappropriately happy"..lol. Excellent presentation on immune vaccines and palliative medicine. But there is also a healer within all of us. Use that to prevent stress and depression

  • @craig265
    @craig265 7 років тому +5

    what happens when you ask for help and your doctor lables you as a drug seeker

    • @GeneralSorrow
      @GeneralSorrow 5 років тому

      You get shut off.

    • @monticae
      @monticae 5 років тому

      People with mental illness are very prone to seek drugs to get better. Sooo what wrong with that?

  • @krool1648
    @krool1648 7 років тому +2

    I wanna try Ketamine.

  • @hksabek7035
    @hksabek7035 7 років тому

    is it a marketing session ?

  • @jamescowan1100
    @jamescowan1100 4 роки тому

    Why does it seem almost everyone except police get mentioned for depression or PTSD? I have read a lot and I see often that police have or are high risk for this illness. I can only imagine how hard it must be for them since they are expected to not show emotions while on duty yet see and deal with our worse nightmares. But it would be great if they can be checked because I know there is a high divorce rate as well as a high suicide rate.

  • @jackfinn4637
    @jackfinn4637 7 років тому +1

    How about encouraging clean healthy diets, good sleep & exercise with probiotics to change the composition of your gut bacteria to reduce inflammation in turn inhibiting depression instead of more antibiotics?

    • @pixiemay9030
      @pixiemay9030 7 років тому +1

      Have you had results personally? It takes a lot of hard work, dedication, trial and error to get the combo right and then I'm still not convinced that this is a cure for some people

    • @fondrees
      @fondrees 5 років тому

      Antibiotics?

  • @starlynkunz615
    @starlynkunz615 7 років тому +1

    To prevent or cure PTSD would be amazing, But does this change you as a person? Does it numb you in a way if that makes sense?

    • @pixiemay9030
      @pixiemay9030 7 років тому

      No

    • @amazingsweet4125
      @amazingsweet4125 4 роки тому +2

      Yes just cure the fear part of it because ptsd is caused by chronic stress disorder. all mental health is caused by over stressing your stressors

  • @duckdumbsmartpplimnotbored5175
    @duckdumbsmartpplimnotbored5175 7 років тому +1

    Depression is just a part of the lifestyle we are now ment to have.

  • @Suprnovaa
    @Suprnovaa 7 років тому +1

    What about MAPS? MDMA?

  • @Katzp3
    @Katzp3 7 років тому +7

    SOMA bitches! let's make Brave New World Real!

  • @bigfootpegrande
    @bigfootpegrande 7 років тому

    What about turning all resources towards minimizing preventable stress and trauma, such as wars and refugees?

  • @quailman8455
    @quailman8455 7 років тому +3

    How many of you have done TMS? Raise your hand!

  • @allinaday9882
    @allinaday9882 Рік тому

    5/2023 Still not legal in majority of US states…

  • @Sevy0815
    @Sevy0815 7 років тому

    ok

  • @CJayin
    @CJayin 7 років тому

    I have both of these. I've been baited

  • @thestateofalaska
    @thestateofalaska 7 років тому +1

    would drugs like this help to "cure" someone who already has PTSD? Or would it just prevent developing it...

    • @juliawebster7134
      @juliawebster7134 7 років тому +2

      ᕕ( ᐛ )ᕗ from how I understood the video it would create a resilience to stress and from my limited understanding of PTSD is that it's triggered by a stressor so maybe the new drug could keep those stressors from hitting as hard.

    • @liz.217
      @liz.217 7 років тому

      ᕕ( ᐛ )ᕗ I have read that it repairs brain functions damaged by severe complex PTSD and can even help after a nervous breakdown. My Dr doesn't do procedure but has a Dr who will for $500. Affordable healthcare ? Not with big pharm in play.

  • @MarihFerreira_Mrs
    @MarihFerreira_Mrs 7 років тому +1

    Banda Calypsol :v

  • @zzzzzzz2012
    @zzzzzzz2012 5 років тому +1

    2017: A person is discussing about drug that could prevent depression and PTSD
    2019: The same person is still discussing about drug that could prevent depression and PTSD.
    What changed?

    • @fondrees
      @fondrees 5 років тому +1

      They've been discussing and using ketamine for depression since 2008. Nothing has changed.big pharma is trying to patent derivatives but havent proven effective. It won't be available via insurance until they can make a fortune on it.

  • @truthisbuoyant5825
    @truthisbuoyant5825 7 років тому +2

    We already have one that does that. Well it's not really a drug, It's weed.

  • @JustT0m752
    @JustT0m752 2 роки тому

    Charlie Munger once said, "if you take heroin, your life will improve for about two weeks".
    I hope Ketamine can help, but lets be very careful. I would recommend people watch the television series Dope Sick on Hulu. This Ketamin hype reminds me of how Oxytocin was hyped as a non addictive opium for pain management. How did that work out for us?
    Last year, 2021, the United States recorded 100,000 deaths from opium overdoses.

  • @jacquelinewoo1900
    @jacquelinewoo1900 7 років тому

    maybe thats why i enjoyed ketamine so much as a party kid given that i have the same background. i preferred it over mdma and lsd depending on what was available. not being a jerk, i mean it.

  • @madisonakagg9453
    @madisonakagg9453 4 роки тому +1

    I have been asking my mental health person for years about ketamine treatments she finally told me about a doctor that gives you ketamine nasal spray treatments. Not only do I suffer from major depression but I also have idiopathic hypersomnolence without medication I can sleep for 30 hours no problem and then wake up still totally exhausted woo hoo

    • @davidanderson8469
      @davidanderson8469 Рік тому

      Psychiatrists are trained to control mental disorders not to prevent them from happening in the first place.

  • @dichotomyofone
    @dichotomyofone 7 років тому +1

    The twist is you were a ghost the entire time.

  • @Chris.Waddell
    @Chris.Waddell 7 років тому

    You know, I have total empathy for those who suffer from PTSD, but is another pill something the world needs?

    • @casinoroyal93
      @casinoroyal93 7 років тому +7

      Chris Waddell for those who has real mental problems yes.

  • @cristianhernandez3099
    @cristianhernandez3099 2 роки тому

    I love how we are being given "stuff" that does not have a purpose for what it is used for but based on some superficial observations of doctors! DO YOU ALL HAVE A DOCTOR THAT OBSERVES YOU FROM MORE THAN 5 MINUTES to send you all drugs and high doses to cure you?

  • @GoEvenHarder
    @GoEvenHarder 7 років тому +2

    Yes it's called nutella

  • @lukusblack6442
    @lukusblack6442 7 років тому +1

    Keeping depression at bay has little to do with narcotics. There are various forms of depression, and much of the issue is based on wavelength. The right light, color, and sounds do a great deal for depression, as does the correct dosage of caffeine.
    PTSD can be kept to a minimum with pot, which won't cost you $200 a bottle.

    • @frankstein5846
      @frankstein5846 7 років тому +2

      lukus black pot combined with junk food is over $200 for same dosage. 😂

    • @lukusblack6442
      @lukusblack6442 7 років тому

      Ok... fair point. lol

    • @frankstein5846
      @frankstein5846 7 років тому

      lukus black I smoked enough in my youth. I'd recommend people don't take drugs at all if they want to avoid issues. PTSD and depression both are signs of mental health issues that need worked through not avoided. But people being people they will go for the bandaid not the cure.

    • @lukusblack6442
      @lukusblack6442 7 років тому

      John Smith
      The pot is meant to dull the pain, not eradicate it. Once you can think clearly without the past haunting you, you can work through your issues properly.

    • @frankstein5846
      @frankstein5846 7 років тому +1

      lukus black Or, here's a novel idea... quit running from the pain and embrace it. It vanishes like the ghost it is if you stop fighting and running from it. Like I said people would rather avoid and numb.

  • @themaninawhitecoatandhat7503
    @themaninawhitecoatandhat7503 7 років тому +4

    the mind is far too complex