Sir, Thank you for kindly answering subscribers questions. I'm a new subscriber and enjoy reading through Q&A's. These are greatly informative. It's refreshing to see someone care enough to try responding. You are appreciated - Cheers! :)
Excess choline above 3,500 mg per day has been shown to increase production of TMAO which increases your chance for heart disease. Best to use CDP-Choline 300 mg 2-times per day and you'll get the benefits of choline and still stay safe.
Thanks for the infos! That was super well presented and straight to the point :) I have a question though The daily recommended intake for choline is 550mg but, as you explained, the choline per weight varies. I'm assuming the daily recommendation is based on the form of choline that is in food which is phosphatidylcholine. With that in mind, how much CDP-choline do you think is needed to get an equivalent? (assuming we're not getting any choline from food)
It depends on what your brain and body need. It varies from person to person. A general rule of thumb with Alpha GPC and CDP-Choline is 300 mg per dose. And that's done 2 or 3-times per day. Some may find that too much choline. But then someone like me would find it too little.
Absolutely love your videos nonstop. Another question again please, would you recommend Aplha GPC or L-Theanine or Both? This is for decisionmaking, energy,focus and learning thanks
I use both with great success. 300 mg Alpha GPC 2 or 3-times per day. And 100 mg L-Theanine morning and noon. Any higher dose and it may make you sleepy.
Very informative. Please I need your advice. I've been having nerve pains in my elbows, back and feet for some years. What do you advice intake for it. I've seen videos of ALA and choline.
Any nootropic that works as an anti-inflammatory should help. Or you can just use Kratom to block the pain. Do a search of Nootropics Expert using the search function top right of the top menu and search for the keyword "anti-inflammatory" and see what turns up.
Yes I do have question, I wonder how Einstein, Newton, Nicola Tesla or Alexander the Great were able to live great fulfilling life and became high achievers, without taking specific choline supplement or buying stacks of nootropics?
That is a great question. It's partially because they had real food to eat. And not the processed garbage you find in our supermarkets today. It's why the "supplement" industry today is a multi-billion dollar industry and growing exponentially year after year. We did not have a dietary supplement industry even 50 years ago. Because we didn't need one. But today we do need one if we want to function optimally.
Toni, choline bitartrate seems to work well for fatty liver disease. It does not make for a good nootropic because it cannot easily cross the blood-brain barrier. But it'll definitely get to your liver.
My current stack.. 150MG of Armodafinil. (Mylan generic) 20MG of Noopept.. 400MG of Caffeine.. 200MG L-Theanine.. 350MG of Choline Bitartrate.. I'm new to nootropics, any advice on if this is an effective stack? Also I didn't know there were differences with Choline. Is Bitartrate not affective? I'm also wondering if the generic Armodafinil I'm taking isn't as effective as the Nuvigil brand.
Nuvigil is Armodafinil. But buying anything other than the brand is a crap shoot unless you really trust the company. Choline Bitartrate cannot cross the blood-brain barrier and is pretty much useless as a nootropic. If you want to increase acetylcholine you need either Alpha GPC or CDP-Choline along with ALCAR and Vitamins B1 and B5. And your ratio of caffeine - L-Theanine is backwards. The best effect is 1:2 ration of caffeine - L-Theanine. Is it effective? It depends on what you are trying to accomplish with your stack.
Thank you very much for the amazing video 👍 Would choline supplement be a good idea in pregnancy? If yes, which one, please? Thank you indeed, All the best
Nadia, I'm NOT a doctor and don't play one on TV. So my answer is coming from what clinicala studies say. And since it does not need to cross the blood-brain barrier most supplements for pregnancy use choline bitartrate which is the least expensive form of choline supplement.
@@NootropicsExpert I truly appreciate your reply. There is 5 mg choline in pregnancy vitamins, recommend daily intake for pregnant women is around 450-500mg. At least what my search so far told me. To be deadly honest, you are an expert with deep knowledge of the choline topic, which is fantastic. My general practice Dr from a small town has no much clue about it, honest. Thank you indeed for your info 🌟
Hi , thank you for this video . i give to my son ADHD the product " mind " from performance lab once per day . i want to try it twice per day but maybe 500 of cdp choline will stimulate him too much .. do you think to combine l-theanine 200 mg twice per day will help to reduce too much activity cause by cdp choline ? thank you
Eric, CDP-Choline is not much of a stimulant. And most of the ingredients in Mind taken at 8 am are gone by noon. So dosing it a 2nd time at noon should help your son for most of the afternoon.
Michael, because some cannot use choline. The best multivitamins in my opinion contain all 13 vitamins and all 13 minerals in their bioactive form and nothing else. Then you add whatever other supplement you need.
Hello, if Alpha GPC is a biproduct of Phosphatidyl Choline. From a nootropic standpoint, would it be better to supplement with Phosphatidyl Choline? In the sense that your body would have a greater storage of choline readily available for conversion
@@obakengmamatela4161 Piping Rock say they have a robust 3rd party testing program for the supplements that they make. As long as the supplement you are considering does not have any toxic "other ingredients" it should be fine. Best to check the "user reviews" as well before you buy.
I can't find any source indicating too much choline creates a serotonin deficiency in the brain. This goes against intuition because both choline and SSRI's are used for treating anxiety, so I'd like you to review your statements on this issue.
Leo, this keeps one coming up and I can't find any proof of this either. If you find anything on this please let me know. It certainly did NOT come from me.
Considering choline can be derived from the phosphatidylcholine found in the cell membranes when there's no alternative, do you think the body will always be in a "limited consumption mode" if we only supplement it with phosphatidylcholine? In other words, will the body thrive on choline or just survive with the smallest required amount if we only give it phosphatidylcholine? Assuming no choline is received from the diet.
It depends on your system's demand for choline to make acetylcholine. If your system can't get enough choline from supplemental PC then it will start raiding brain cell membranes. Better to use another choline supplement I think.
yes the symptoms can be similar. But no, there is no blood test to measure this because acetylcholine is synthesized in brain cells. And the only accurate way to measure them is to autopsy your brain.
@@lanadecker8800 It isn't but what is helpful is as you gain more experience with these supplements you'll know what to watch for. And you'll know if you took too much and when to back off.
Angela, I do not think you will get much benefit from using a regular choline supplement like Alpha GPC. But medicine has been successfully treating MS with acetylcholinesterase inhibitors. There are several natural AChE inhibitors you can try including: Huperzine-A which is the most effective. But others include Rosemary, Magnolia Bark extract, and Chaga Mushroom extract.
Thanks for the video. I am taking a nootropic stack called Brainzyme and it has 145 mg choline per capsule (I take 2 as recommended). Would this be regarded as a high dosage of choline? Thanks again.
Thomas PC provides the choline needed to make acetylcholine. It easily gets into your brain. The only other two viable alternatives are Alpha GPC or CDP-Choline.
Can Ptosis (drooping eyelid caused by Botox and or having it naturally) be aided/fixed by Choline Citrate similar to shoulder muscle pain? If not, is there potentially another nootropic that can help with nerve related issues?
Bob, I'm not aware of Choline Citrate benefiting that issue. But there are several nootropics that support nerve repair and regeneration including Lion's Mane Mushroom. Do a search of this channel for "BDNF" and "Nerve Growth Factor". And my website and what else turns up.
@@NootropicsExpert O god thank you. You replied. I have a condition for last few months or may be one year or so. I had low methylation symptoms. Then I started eating methionine rich foods and taking l-methionine supplements. It improved my symptoms a little bit then I started SAMe on top of that. One day at night, I experienced like my liver wanted to burst. I felt like I was going to die. That day I took SAMe and methylfolate and was taking choline as well. i did not know what was happening. After that day I continuously yawned for many days and my liver area felt really heavy. And after researching, I came to know that maybe I injured my liver from too much methionine. Now whenever I eat a methionine containing meal. I feel sick and my liver and kidneys hurt. I dont know what to do except for avoiding the methionine in diet. Please help me in any way if you have any information. I am willing to pay for help. Please help. This thing ruined my life. I have insomnia also due to anxiety depression disorder for last 4-5 years. HELP🙏. Maybe it is related to Methionine adenosyl transferase gene in my liver (MAT1A, MAT2A). according to my sleepless research.
If you think liver damage is the true issue find a high quality Milk Thistle extract and start using it 3-times per day. It has been shown to be a very effective supplement for liver repair.
For what reason? if you are looking to use lecithin for its PS or PC content unless you know exactly how much of either is in that supplement you'll not have any idea if you are getting its benefits. Likely until it's too late because the changes of using the real thing can be subtle but profound.
It is highly doubtful. But it depends on what your body and brain need. Better to get phosphatidylcholine (PC) made from sunflower lecithin for a true source of choline.
What are you using the choline citrate for? Because it cannot cross the blood-brain barrier. As a nootropic, a far better option is Alpha GPC or CDP-Choline.
Jesus Christ, I don't no which one to try???? I'm 52 male, I have a Liver Transplant and I have been forgetting things and saying words wrong the past 3 months. I went to the Dr. he said it was nothing. I do Intermitting fasting 4 days a week, 18-20 hours. Which one should I use to see if it works, when ever I take any new supplements I always moniter my blood to make sure it dosen't interact with my meds and make sure it doesn't hurt my liver or kidneys.
For learning and memory the most basic stack is 500 mg L-Tyrosine twice per day, 300 mg Alpha GPC twice a day, a high quality B-Complex life the one from Life Extension, 1,000 mg DHA (Omega-3). And for you likely 100 mg Phosphatidylserine (PS) twice per day.
@@NootropicsExpert Great idea! 😃 I haven't thought about that combination. So far I decided to try Alpha GPC and Bacopa Monieri with B1, B3, B5, B8, Iodine (Icelandic Kelp - I have an unopened big bottle of these tablets left over), Ginko Biloba, Zinc, Copper, Selenium and Chromium Picolinate. 🤩
@@NootropicsExpert i am interested in taking the 2 you take and was hoping to find one combined together as a trial to save money. The closest i found was alpha gpc with uridine. You mentioned cdp turns to uridine in the brain so I was thinking this would work?
@@freeagent6203 yes, it should work. I personally use Mind Lab Pro which contains Cognizin (branded form of CDP-Choline) with Alpha GPC. Does that answer your question? And sorry I'm just getting around to this.
Probably it would benefit. You start losing Phosphatidylserine (PS) in your 20's and most people are deficient in several nutrients. One of which is choline.
Pls help me. I have taken brahmi(bacopa), shankapushpi and other herbs in tablet which is help in increasing acetylcholine after 6 weeks motivation gone, mind changed, depression, anxiety, no deep sleep, vivid dreams, wakefulness. How to decrease acetylcholine naturally or medically?
You need a natural anticholinergics to reduce acetylcholine. And those include Forskolin, Kava and Lipoic Acid. Or you can use one of the racetams to reduce it even quicker.
Daniel, I use both of them. Citicoline in Mind Lab Pro along with an Alpha GPC supplement. Both contribute a choline molecule for the synthesis of acetylcholine. But come in at different parts of the synthesis pathway.
@@NootropicsExpert is it possible this could help with a skin condition i have. Whenever i try to exercise my skin tends to tingle burn, go red and then itch. Its partly a skin problem but at the same time i believe its something internal, whether its blood flow or a nervous system response because its like when i train there's a trigger in the brain that causes me to itch whether its a nerve i don't know. Do you think this could help or no any other product that can help with this
@@tmoneyofficial1 Regular choline supplements like Alpha GPC and CDP-Choline are not known for benefiting the skin. DMAE on the other hand is often used in skin cosmetics and it influences acetylcholine. But it also reduces lipofuscin which show up internally and externally as brown spots on your skin. And it tames free radicals which can also cause skin inflammation. ua-cam.com/video/Ss7vjHd5CUQ/v-deo.html
Hello, I bought some Alpina gpc of 300mg and felt awful - depressed, unmotivated, no energy and slow. After that experience I got scared and never really tried any choline supplement again. But I've heard so many good things about choline that I don't want to write it off just yet. Do you have any suggestions of how should I approach this issue? Thanks a lot and great video!
Great question but impossible to answer. Because you may respond better to one than the other. Many people use both including myself because they work well together. You could try a lower dose of each and see how it works for you. Then try them one at a time and see if you notice a difference.
Hi, I've been trying piracetam recently. In the beginning it was absolutely a great nootropic, but then after a couple of days I started feeling sleepy, falling asleep whenever I took piracetam. I tried Alpha GPC, but it felt like it would reduce sleepiness for a short time before I got sleepy again. I would try up to 600mg Alpha GPC for 1800mg piracetam, but the sleepy feeling wouldn't go away. Do you have any ideas why I am getting sleepy from piracetam? Much Obliged.
Raqib, it sounds like you are deficient in acetylcholine. Try Piracetam with CDP-Choline and see if that works better for you. You don't want to overdose on a choline supplement. But Piracetam affects acetylcholine use in your brain in a major way. If it does not have enough to work with you'll either feel nothing or possibly what you are experiencing. If neither choline supplement helps then Piracetam is the wrong nootropic for you.
@@NootropicsExpert thank you, I will try cdp choline soon. I'm wondering if my body doesn't produce enough acetylcholine and gets tired because I undermethylate? For that reason, I will also test methylfolate, methylcobalamin, creatine monohydrate, and ALCAR to see what works with piracetam.
Can I just get told what is the best type? I am so brain fogged by all the science stuff (which I'll never remember);without knowing what the best options are for such a long video
Martina, the best choline supplements for your brain are Alpha GPC and CDP-Choline. Each provides a choline molecule for the synthesis of acetylcholine. But some respond better to one than the other. I suggest you try both but one at a time and see how you feel before you decide what to use long-term.
Stefan, you will get some choline from egg yolks. But depending on what you are using the extra choline for, there is no accurate way to measure how much choline you are getting from each egg.
Sir, Thank you for kindly answering subscribers questions. I'm a new subscriber and enjoy reading through Q&A's. These are greatly informative. It's refreshing to see someone care enough to try responding. You are appreciated - Cheers! :)
Welcome aboard Pip! Thanks.
Great info! This is what UA-cam should be used for! But I need a week to process this information though 😅
Good luck!
Thanks for this great work you are doing , I am now able to connect the dots !!!
Bhupen, thank you and happy it's helping you.
GREAT Information as ALWAYS! With Much Gratitude and Appreciation for the Work that you do. THANK YOU!
And thank you for stopping by.
Amazing video so much info. Almost more than I can hold in my head at once! On screen text would help. Hope you’re still making vids
I just put up two new ones in the last week. More to come. And I am getting better at including on screen text to make it easier for people to follow.
Hi Doc, I love your videos, so much concise information. Greatly appreciated.
Thank you!
What a brilliant rundown. Very informative. I'll be trying the mr happy stack shortly, looking forward to experiencing it. Cheers
Thank you Josh. Much appreciated.
Thanks for your amazing information I would like to confirm if choline as bitartrate is not good for heart since I am 69 years old
Excess choline above 3,500 mg per day has been shown to increase production of TMAO which increases your chance for heart disease.
Best to use CDP-Choline 300 mg 2-times per day and you'll get the benefits of choline and still stay safe.
Love this guy ! All yours videos are great ! Thank you ! :)
Generally, what dosage does one need to take to experience those negative side effects, and what is a safe dose not to experience them?
Amazing & useful info. Thank you!!
Glad it was helpful! Thank you!
Thank you, message received this morning, MYELIN.
Thanks for the infos! That was super well presented and straight to the point :) I have a question though
The daily recommended intake for choline is 550mg but, as you explained, the choline per weight varies. I'm assuming the daily recommendation is based on the form of choline that is in food which is phosphatidylcholine. With that in mind, how much CDP-choline do you think is needed to get an equivalent? (assuming we're not getting any choline from food)
It depends on what your brain and body need. It varies from person to person.
A general rule of thumb with Alpha GPC and CDP-Choline is 300 mg per dose. And that's done 2 or 3-times per day.
Some may find that too much choline. But then someone like me would find it too little.
Absolutely love your videos nonstop. Another question again please, would you recommend Aplha GPC or L-Theanine or Both? This is for decisionmaking, energy,focus and learning
thanks
I use both with great success. 300 mg Alpha GPC 2 or 3-times per day. And 100 mg L-Theanine morning and noon. Any higher dose and it may make you sleepy.
I want to know if Choline Bitartrate Isotipol is good for a person with fatty liver. I enjoyed your video. Good information. Thanks
Clinical studies in animals show that it's effective: www.thieme-connect.com/products/ejournals/abstract/10.1055/s-2007-972975
@@NootropicsExpert thank you
Very informative, thanks
Glad it was helpful! Thank you!
Is phosphatidyl choline considerd a good choline source? Can it replace citicoline or apha gpc?
It's is a good choline source but will not act as fast to make acetylcholine as Citicoline or Alpha GPC.
Thank you for sharing this great info 👍
I want to use DAME to try treat my skin pigmentation issues. Is it ok to take it together with Alpha GPC?
DMAE should be used with Alpha GPC
Which specific choline is best for Fatty Liver ? Thank you !
Phosphatidylcholine (PC)
@@NootropicsExpert It arrived yesterday. Tomorrow, my Kinnesiology doctor will test me to see if the mg. I bought is the correct one. THANKS !
Very informative. Please I need your advice. I've been having nerve pains in my elbows, back and feet for some years. What do you advice intake for it. I've seen videos of ALA and choline.
Any nootropic that works as an anti-inflammatory should help. Or you can just use Kratom to block the pain.
Do a search of Nootropics Expert using the search function top right of the top menu and search for the keyword "anti-inflammatory" and see what turns up.
Hey! Would I be able to take phentylparacitame + Alpha GPC + Choline Bitartrate ??? Awesome videos! I love learning so much !!
Daniel, if you mean Phenylpiracetam then yes you need to use a choline supplement. Preferably Alpha GPC.
Yes I do have question, I wonder how Einstein, Newton, Nicola Tesla or Alexander the Great were able to live great fulfilling life and became high achievers, without taking specific choline supplement or buying stacks of nootropics?
That is a great question. It's partially because they had real food to eat. And not the processed garbage you find in our supermarkets today.
It's why the "supplement" industry today is a multi-billion dollar industry and growing exponentially year after year. We did not have a dietary supplement industry even 50 years ago. Because we didn't need one. But today we do need one if we want to function optimally.
Awesome videos!!
Thank you Felipe. Kind of you to say so.
what daily dose for alpha gpc and citicoline stack please- great video
300 mg Alpha GPC and 300 mg Citicoline twice per day.
Any suggestions how to naturally reduce Acetylcholine (Alpha GPC makes me unfocused and nauseous)? Thank you for informing us! 😊
Forskolin, Kava, R-Lipoic Acid, and any of the racetams (i.e. Piracetam).
@@NootropicsExpert Thank you! 🥰👍
If I'm trying to target my liver, what is the best choline you'd suggest?
Toni, choline bitartrate seems to work well for fatty liver disease. It does not make for a good nootropic because it cannot easily cross the blood-brain barrier. But it'll definitely get to your liver.
My current stack.. 150MG of Armodafinil. (Mylan generic) 20MG of Noopept.. 400MG of Caffeine.. 200MG L-Theanine.. 350MG of Choline Bitartrate.. I'm new to nootropics, any advice on if this is an effective stack? Also I didn't know there were differences with Choline. Is Bitartrate not affective? I'm also wondering if the generic Armodafinil I'm taking isn't as effective as the Nuvigil brand.
Nuvigil is Armodafinil. But buying anything other than the brand is a crap shoot unless you really trust the company.
Choline Bitartrate cannot cross the blood-brain barrier and is pretty much useless as a nootropic. If you want to increase acetylcholine you need either Alpha GPC or CDP-Choline along with ALCAR and Vitamins B1 and B5.
And your ratio of caffeine - L-Theanine is backwards. The best effect is 1:2 ration of caffeine - L-Theanine.
Is it effective? It depends on what you are trying to accomplish with your stack.
Thank you very much for the amazing video 👍
Would choline supplement be a good idea in pregnancy? If yes, which one, please?
Thank you indeed, All the best
Nadia, I'm NOT a doctor and don't play one on TV. So my answer is coming from what clinicala studies say. And since it does not need to cross the blood-brain barrier most supplements for pregnancy use choline bitartrate which is the least expensive form of choline supplement.
@@NootropicsExpert I truly appreciate your reply.
There is 5 mg choline in pregnancy vitamins, recommend daily intake for pregnant women is around 450-500mg. At least what my search so far told me.
To be deadly honest, you are an expert with deep knowledge of the choline topic, which is fantastic.
My general practice Dr from a small town has no much clue about it, honest.
Thank you indeed for your info 🌟
Hi , thank you for this video . i give to my son ADHD the product " mind " from performance lab once per day . i want to try it twice per day but maybe 500 of cdp choline will stimulate him too much .. do you think to combine l-theanine 200 mg twice per day will help to reduce too much activity cause by cdp choline ?
thank you
Eric, CDP-Choline is not much of a stimulant. And most of the ingredients in Mind taken at 8 am are gone by noon. So dosing it a 2nd time at noon should help your son for most of the afternoon.
Why doesn’t many vitamin companies add this to the vitamins they sale ten? Why isn’t anyone pushing them to add choline if it is so important
Michael, because some cannot use choline. The best multivitamins in my opinion contain all 13 vitamins and all 13 minerals in their bioactive form and nothing else. Then you add whatever other supplement you need.
Hello, if Alpha GPC is a biproduct of Phosphatidyl Choline. From a nootropic standpoint, would it be better to supplement with Phosphatidyl Choline? In the sense that your body would have a greater storage of choline readily available for conversion
Not necessarily. I have had much better success using Alpha GPC as a nootropic for more acetylcholine in my brain.
@@NootropicsExpert Thank you. Lastly, do you have any words to share on the supplements from ''PipingRock'' ?
@@obakengmamatela4161 Piping Rock say they have a robust 3rd party testing program for the supplements that they make. As long as the supplement you are considering does not have any toxic "other ingredients" it should be fine. Best to check the "user reviews" as well before you buy.
@@NootropicsExpert Will do, thanks again!
I have Adhd and Take it with Vyvanse is it Good to take 200-600Mg of Alpha Gpc or Has it effect on Dopamine ?
The recommended adult dosage for Alpha GPC is 300 mg 3-times per day. It helps release more dopamine. Not make it but release it.
So, a sprinkle cream of tarter on my duck eggs might help with absorption?
I can't find any source indicating too much choline creates a serotonin deficiency in the brain. This goes against intuition because both choline and SSRI's are used for treating anxiety, so I'd like you to review your statements on this issue.
Leo, this keeps one coming up and I can't find any proof of this either. If you find anything on this please let me know. It certainly did NOT come from me.
@@NootropicsExpert Alright, thanks ;)
Hi wich one good for fatty liver and cell membrane?
Phosphatidylcholine (PC).
Hi, I was wondering if The Pure Synergy brand Choline Complex is any good at all to take? Kinds regards
They do not say what kind of choline they use in their supplement. You are better off getting a good quality Alpha GPC or CDP-Choline instead.
Considering choline can be derived from the phosphatidylcholine found in the cell membranes when there's no alternative, do you think the body will always be in a "limited consumption mode" if we only supplement it with phosphatidylcholine?
In other words, will the body thrive on choline or just survive with the smallest required amount if we only give it phosphatidylcholine? Assuming no choline is received from the diet.
It depends on your system's demand for choline to make acetylcholine. If your system can't get enough choline from supplemental PC then it will start raiding brain cell membranes. Better to use another choline supplement I think.
So symptoms of too much and not enough are the same? Is there a blood test that tells you where you are?
yes the symptoms can be similar. But no, there is no blood test to measure this because acetylcholine is synthesized in brain cells. And the only accurate way to measure them is to autopsy your brain.
@@NootropicsExpert well, that's not very helpful, is it?
@@lanadecker8800 It isn't but what is helpful is as you gain more experience with these supplements you'll know what to watch for. And you'll know if you took too much and when to back off.
Can I take this if I have both Myasthenia Gravis and Sjogrens, I have weakness in standing, walking, arms, droopy eye(s) and speech problems.
Angela, I do not think you will get much benefit from using a regular choline supplement like Alpha GPC. But medicine has been successfully treating MS with acetylcholinesterase inhibitors.
There are several natural AChE inhibitors you can try including: Huperzine-A which is the most effective. But others include Rosemary, Magnolia Bark extract, and Chaga Mushroom extract.
Thanks for the video. I am taking a nootropic stack called Brainzyme and it has 145 mg choline per capsule (I take 2 as recommended). Would this be regarded as a high dosage of choline? Thanks again.
Harryk 145 mg of choline is very low. No matter what form of choline you're using.
Really confusing can you tell me what to buy to help fatty liver? I have heard choline is supposed to help fatty liver
Helena choline bitartrate will help with fatty liver. It does not work well for brain health. But it will help your liver.
Phosphatidylcholine supplements is same as choline??
Thomas PC provides the choline needed to make acetylcholine. It easily gets into your brain. The only other two viable alternatives are Alpha GPC or CDP-Choline.
Which form is best to remove fatty liver and boost brain memory?
Phosphatidylcholine (www.ncbi.nlm.nih.gov/pmc/articles/PMC7170405/)
@@NootropicsExpert Thank you.. Is it ok to take Choline Bitartrate and Alpha GPC at the same time? My goal is liver cleanser and for brain too.
@@jeffreyborja You can certainly take both at the same time. But be careful that you don't boost acetylcholine too much.
@@NootropicsExpert :-) I have Choline Bitartrate at 600mg. What dose of Alpha GPC I could take? Thank you again.
@@jeffreyborja Try the standard dose of 300 mg and see if that works. If it's to much then scale back your dosage.
Can Ptosis (drooping eyelid caused by Botox and or having it naturally) be aided/fixed by Choline Citrate similar to shoulder muscle pain? If not, is there potentially another nootropic that can help with nerve related issues?
Bob, I'm not aware of Choline Citrate benefiting that issue. But there are several nootropics that support nerve repair and regeneration including Lion's Mane Mushroom. Do a search of this channel for "BDNF" and "Nerve Growth Factor". And my website and what else turns up.
ty
So the symptoms of too much choline are basically the same as too little choline?
That is generally true.
Can you recommend a form of Choline for pregnancy?
Studies show either one or both CDP-Choline and Alpha GPC: www.ncbi.nlm.nih.gov/pmc/articles/PMC6722688/
what is the difference between choline and choline chloride.
Haluk, _choline_ in is used in the human body to make _acetylcholine_ . Choline chloride is used in chicken feed to accelerate their growth.
Is choline good for kidney problems?
It may help as long as you keep the dose on the low end.
@@NootropicsExpert O god thank you. You replied. I have a condition for last few months or may be one year or so.
I had low methylation symptoms. Then I started eating methionine rich foods and taking l-methionine supplements.
It improved my symptoms a little bit then I started SAMe on top of that.
One day at night, I experienced like my liver wanted to burst. I felt like I was going to die. That day I took SAMe and methylfolate and was taking choline as well.
i did not know what was happening. After that day I continuously yawned for many days and my liver area felt really heavy.
And after researching, I came to know that maybe I injured my liver from too much methionine.
Now whenever I eat a methionine containing meal. I feel sick and my liver and kidneys hurt. I dont know what to do except for avoiding the methionine in diet.
Please help me in any way if you have any information. I am willing to pay for help. Please help. This thing ruined my life. I have insomnia also due to anxiety depression disorder for last 4-5 years.
HELP🙏.
Maybe it is related to Methionine adenosyl transferase gene in my liver (MAT1A, MAT2A).
according to my sleepless research.
If you think liver damage is the true issue find a high quality Milk Thistle extract and start using it 3-times per day. It has been shown to be a very effective supplement for liver repair.
Hello, I have lion's mane and alpha gpc , plz tell dosage to use both , thanx ? Can I use in empty stomach with water ?
Try 500 mg Lion's Mane and 300 mg Alpha GPC twice per day. Morning and noon.
@@NootropicsExpert u mean 250mg lion mane and 150 mgs alpha gpc in morning and then same at noon ? Thankyou . And empty stomach is ok ?
@@imtiazjat Negative. I mean that dose in the morning and the same dose again at noon. Empty stomach is fine.
@@NootropicsExpert thankyou so much ♥️🙏
Can u just take sunflower lecthin?
For what reason? if you are looking to use lecithin for its PS or PC content unless you know exactly how much of either is in that supplement you'll not have any idea if you are getting its benefits. Likely until it's too late because the changes of using the real thing can be subtle but profound.
Can you take Phosphatidylcholine and CDP choline + inositol together?
You can take them together but not sure why you would use PC AND CDP-Choline. If it was to increase acetylcholine then CDP-Choline would be enough.
Yes, it is to increase acetylcholine so that’s good to know I don’t need need PC and CDP-Choline is enough. Thank you so much!
Can taking sunflower lecithin supplements make up for choline?????in our body
It is highly doubtful. But it depends on what your body and brain need. Better to get phosphatidylcholine (PC) made from sunflower lecithin for a true source of choline.
there seem to be so few options for a choline citrate supplement. Any recommendations?
What are you using the choline citrate for? Because it cannot cross the blood-brain barrier. As a nootropic, a far better option is Alpha GPC or CDP-Choline.
Is 80mg of choline per day safe?
What form of choline?
Does choline feed or cause prostate cancer?
No
Anybody have results from what you decided to apply from this presentation?
will choline bitartrate still work for muscle recovery like citrate though? to some extent? its all i can get right now
Yes it should.
Jesus Christ, I don't no which one to try???? I'm 52 male, I have a Liver Transplant and I have been forgetting things and saying words wrong the past 3 months. I went to the Dr. he said it was nothing. I do Intermitting fasting 4 days a week, 18-20 hours. Which one should I use to see if it works, when ever I take any new supplements I always moniter my blood to make sure it dosen't interact with my meds and make sure it doesn't hurt my liver or kidneys.
For learning and memory the most basic stack is 500 mg L-Tyrosine twice per day, 300 mg Alpha GPC twice a day, a high quality B-Complex life the one from Life Extension, 1,000 mg DHA (Omega-3). And for you likely 100 mg Phosphatidylserine (PS) twice per day.
@@NootropicsExpert Thanks
Hello David can you mix alpha gpc with b complex
Yes
What do you think about combining Ashwagandha with Alpha gpc to reduce harmful levels of cortisol (or stress in general)?
@@RebelleFleur5
Better I think to use Ashwagandha and L-Theanine to control excess cortisol.
@@NootropicsExpert Great idea! 😃 I haven't thought about that combination.
So far I decided to try Alpha GPC and Bacopa Monieri with B1, B3, B5, B8, Iodine (Icelandic Kelp - I have an unopened big bottle of these tablets left over), Ginko Biloba, Zinc, Copper, Selenium and Chromium Picolinate. 🤩
What about just taking alpha gpc with uridine?
Chris, I don't understand your question. 300 mg Alpha GPC with Uridine Monophosphate is a normal stack.
@@NootropicsExpert i am interested in taking the 2 you take and was hoping to find one combined together as a trial to save money. The closest i found was alpha gpc with uridine. You mentioned cdp turns to uridine in the brain so I was thinking this would work?
@@freeagent6203 yes, it should work. I personally use Mind Lab Pro which contains Cognizin (branded form of CDP-Choline) with Alpha GPC. Does that answer your question? And sorry I'm just getting around to this.
Would choline benefit someone in their mid twenties? (you mentioned good for 40s+)
Probably it would benefit. You start losing Phosphatidylserine (PS) in your 20's and most people are deficient in several nutrients. One of which is choline.
NootropicsExpert thank you so much for the reply!!!
Pls help me. I have taken brahmi(bacopa), shankapushpi and other herbs in tablet which is help in increasing acetylcholine after 6 weeks motivation gone, mind changed, depression, anxiety, no deep sleep, vivid dreams, wakefulness. How to decrease acetylcholine naturally or medically?
You need a natural anticholinergics to reduce acetylcholine. And those include Forskolin, Kava and Lipoic Acid. Or you can use one of the racetams to reduce it even quicker.
So you can take alpha gpc and cdp choline at the same time?
Daniel, I use both of them. Citicoline in Mind Lab Pro along with an Alpha GPC supplement. Both contribute a choline molecule for the synthesis of acetylcholine. But come in at different parts of the synthesis pathway.
i don't get it choline is needed to improve focus and memory, but then too much choline would cause lack of memory and brain fog??
Too much of any supplement can cause problems. Balance is key.
Is it ok for a 18 year old to take this
Choline supplements should be safe if you are 18. Because it is perfectly natural and will not alter your developing brain microbiology.
@@NootropicsExpert is it possible this could help with a skin condition i have. Whenever i try to exercise my skin tends to tingle burn, go red and then itch. Its partly a skin problem but at the same time i believe its something internal, whether its blood flow or a nervous system response because its like when i train there's a trigger in the brain that causes me to itch whether its a nerve i don't know. Do you think this could help or no any other product that can help with this
@@tmoneyofficial1 Regular choline supplements like Alpha GPC and CDP-Choline are not known for benefiting the skin.
DMAE on the other hand is often used in skin cosmetics and it influences acetylcholine. But it also reduces lipofuscin which show up internally and externally as brown spots on your skin. And it tames free radicals which can also cause skin inflammation. ua-cam.com/video/Ss7vjHd5CUQ/v-deo.html
@@NootropicsExpert just as I was talking about this I see this message. Thank you. I will check it out
Hello, I bought some Alpina gpc of 300mg and felt awful - depressed, unmotivated, no energy and slow.
After that experience I got scared and never really tried any choline supplement again. But I've heard so many good things about choline that I don't want to write it off just yet.
Do you have any suggestions of how should I approach this issue?
Thanks a lot and great video!
Tony, I'd stay away from choline supplements if I were you based on that experience. My wife can't use a choline supplement either.
Hi thanks for all your upload s. Between Alpha GPC and Citicoline, which one would you recommend for someone in his mid 20s take? Thanks!
Great question but impossible to answer. Because you may respond better to one than the other. Many people use both including myself because they work well together. You could try a lower dose of each and see how it works for you. Then try them one at a time and see if you notice a difference.
Do you think combining Choline bitartrate and phosphatidylserine works?
Hi, I've been trying piracetam recently. In the beginning it was absolutely a great nootropic, but then after a couple of days I started feeling sleepy, falling asleep whenever I took piracetam. I tried Alpha GPC, but it felt like it would reduce sleepiness for a short time before I got sleepy again. I would try up to 600mg Alpha GPC for 1800mg piracetam, but the sleepy feeling wouldn't go away. Do you have any ideas why I am getting sleepy from piracetam? Much Obliged.
Raqib, it sounds like you are deficient in acetylcholine. Try Piracetam with CDP-Choline and see if that works better for you.
You don't want to overdose on a choline supplement. But Piracetam affects acetylcholine use in your brain in a major way. If it does not have enough to work with you'll either feel nothing or possibly what you are experiencing.
If neither choline supplement helps then Piracetam is the wrong nootropic for you.
@@NootropicsExpert thank you, I will try cdp choline soon. I'm wondering if my body doesn't produce enough acetylcholine and gets tired because I undermethylate? For that reason, I will also test methylfolate, methylcobalamin, creatine monohydrate, and ALCAR to see what works with piracetam.
@@RaqibZaman how did it go dear?
Can I just get told what is the best type? I am so brain fogged by all the science stuff (which I'll never remember);without knowing what the best options are for such a long video
Martina, the best choline supplements for your brain are Alpha GPC and CDP-Choline. Each provides a choline molecule for the synthesis of acetylcholine.
But some respond better to one than the other. I suggest you try both but one at a time and see how you feel before you decide what to use long-term.
Does choline bitarate smells like fish ???
yes
i take 5gr per day .... holine and inositole
a few extra raw egg yolks per day?
Stefan, you will get some choline from egg yolks. But depending on what you are using the extra choline for, there is no accurate way to measure how much choline you are getting from each egg.
Whenever I take choline in any form even in low doses, I get lethargic, foggy, feels like I am dreaming. I probably already get alot in my diet.
Sounds like choline supplements are just the wrong supplement for you. My wife has the same reaction.
My wife turns into the wicked witch of the west without taking any choline 😳
😂😂
My wife is the opposite and turns into the wicked witch of the west with just the tiniest amount of a choline supplement.