The Nephron

Access my FREE Online Membership today → www.thenotedan...
___
Unlock my Premium Tutoring Memberships → www.thenotedan...
Lifetime Access to Online Anatomy Course
Foundational Q&A Cards Per Video
Notes and Key Takeaways
Downloadable Documents
Flashcards for Each Course
Weekly Group Tutoring Sessions
Direct Tutoring Sessions
___
Discover A Simplified Approach to Master the Complexity of Anatomy with me, Dr. David Morton ... The Noted Anatomist!
This brief video tutorial discusses the nephron, renal corpuscle, renal tubules and JG apparatus:
0:00​​. Introduction
0:20. Nephron foundations
- 0:24. Overview of nephron (parts)
- 1:34. Key fluids. plasma, filtrate, tubular fluid, urine, extracellular fluid (ECF)
- 2:21. Key physiological processes. filtration, reabsorption, secretion, excretion
- 3:14. Two types of nephrons: Cortical nephrons and Juxtaglomerular nephrons
6:00. Renal corpuscle
- 6:03. Glomerular (fenestrations) and mesangial cells
- 8:12. Glomerular basement membrane (GBM)
- 9:01. Bowman's capsule and Bowman's space
- 9:29. Podocytes and filtration slits
- 11:43. Glomerular filtration apparatus
- 13:28. Vascular pole and urinary pole
13:50. Renal tubules
- 15:38. Proximal convoluted tubule (PCT)
- 18:30. Loop of Henle
- 22:09. Countercurrent multiplier and Countercurrent exchanger (overview)
- 25:57. Distal convoluted tubule (DCT)
- 28:05. Collecting ducts (CD)
- 29:27. Without ADH
- 30:28. With ADH
- 31:40. With Aldosterone and ADH
32:54. Juxtaglomerular apparatus
- 33:21. Juxtaglomerular cells
- 34:15. Macula densa cells
- 35:24. Mesangial cells
35:38. In-a-Nutshell
26:59​​. Acknowledgements

[@mxbr1356]

Again saving my Gluteus just before exams. Please never stop making these extraordinary videos.

[@Sinnistering]

You have a gift for teaching, Dr. Morton. I have not taken any anatomy, and I only know a bit about the body from my mom's career as a nurse/nursing educator, and yet I feel I can follow along incredibly well. I've watched some of your other videos, but I wanted to come back to comment on the one that brought me to your channel because it's a complicated and circuitous process, yet you break it down so well. Beyond that, and this is a terribly under-valued skill, you make it fun. You sprinkle a few jokes in, you have the SHIING~ catchphrase that I love. An awesome combo that leads to a fantastic educator.

[@TheNotedAnatomist]

hey, thank you so much for the very kind comments. Much appreciated. This video in particular is one that I have spent two or three years and preparing for it.

[@widaltaf5115]

Legendary
I haven’t seen a single nephrology anatomy/physiology video better than this one 💯

[@victordoamaral6394]

Your videos are amazingly easier to understand compared to all anatomy/physiology teachers I ever had. Please keep it up 🙏

[@TheNotedAnatomist]

Thank you, I will

[@louismarkov5524]

You do not know how much I need this video. Thank you Anatomist.

[@zainulabidinzai397]

Professor plz be active🥺 and upload more videos on regular basis.. We really love💕 you and wana learn from you🙏🤍

[@niceguy3604]

Yesterday i completed my chapter on "excretory products and thier elimination".... And, today volva revision video.... Thx sir

[@Rimonabantmedico]

This channel deserves more view ❤

[@atitayaroumwong3469]

Thank you for making video to share knowledge . Clarity on difficult and complex matters but fully explained every part understand very impressed

[@RameshKuldeep]

OMG so much details with so much simplifying i don't how many i have read and how many more i have to read to know this muchh detail which you gave me in 40.min. thanku so much Doctor
I'm from India hatts off your efforts please keep making these video thanku again.

[@clinicalpediatrics]

Great video Sir♥️

[@Muniera]

You have such remarkable skill to explain physiology concepts 🙏🏼

[@dom6783]

This is like the best video ever

[@anchtain6971]

i did not finish the video yet
but i must thank you befor finishing it thank you so much
thank you for helping us and have a good day

[@babashka9987]

Thank you for your perfectly detailed video, and thanks to the supreme designer of these extraordinary filters🙏🙏🙏🙏

[@TheNotedAnatomist]

Thanks

[@mubangamusakalu5553]

Wonderful video really enjoy your videos

[@terryrogers8347]

Thank you for the great info

[@humeyraer5649]

explained really awesomely

[@twanaomar2003]

💎Masterpiece💎 I should send this to my Histology teacher.
(Gratitudes) can not appreciate this art.

[@zakirzak1494]

🥰😍🤩💯💯Wow, wow ... a beautiful explanation of a complex process...thank you

[@TheNotedAnatomist]

Welcome 😊

[@andrewpleva]

3:33 Great video, just would like to add that the cortical nephrons (+juxtaglomerular) have their Loop of Henle in the medulla contradicting your diagram. The difference comes from the position of the glomerulus, length of the loop of Henle, function and frequency.
8:17 Glomerular Basement Membrane is a misleading term- mainly the basement membrane part. Even though many books may use the term (Basement membrane) technically speaking, a basement membrane is comprised of a basal lamina and a reticular lamina (non existent in this case) therefore it should be called the Glomerular basal lamina.
9:54 Just for those wanting more information, podocytes have primary processes (called trabeculae) and secondary processes coming off of the trabeculae (called pedicles). These pedicles interdigitate creating the filtration slits.
At 11:30 im pretty sure that the pedicel is not a process off of the secondary processes. But if someone knows that would be great!
18:32 I was thought that the Loop of Henle was comprised of a descending straight limb, intermediate tubule and a ascending straight limb. After reading into Junqueira's you were right thanks!
Great video thank you Dr. Morton!

[@thomaskeating7539]

Truly amazing, keep it up.

[@victoriaabrahams6193]

Amazing ! Thank you !

[@TheNotedAnatomist]

Thank you too!

[@reyana9759]

i can’t thank you enoughh such a great video

[@TheNotedAnatomist]

Happy to help

[@r_ostad_s]

Thanks!

[@TheNotedAnatomist]

Wow … thank-you so much for the thoughtful gift. Do you know that out of all of the anatomy and physiology tutorials I have created over the past 9 years this one on the nephron is one that I have spent the most time on and am most proud of? Thank-you … this made my day. Sincerely, David

[@psychiatristpsychiatrist2093]

Please upload the video Autonomic Nervous System Anatomy and physiology

[@nygreenguy]

Curious how you got those bw images of the glomerulus? I see you said "used by Permission" but I would love to have images like that for my class.

[@TheNotedAnatomist]

Hi ... i illustrated the B&W images so i could add color to hilight different parts. Happy to share if you would like to use the image. Send me your email.

[@nolsih]

Superb...

[@TheNotedAnatomist]

Thanks 🤗

[@muqtarjamaegal6071]

Please liver physiology

[@ketoonkratom]

God Bless Everyone Love One Another :)

[@guytelfer1353]

Excellent, how about part 2 disecting the role of rbc's in the bowma ns capsule , levels and concentrations, diffusion, ect?, cool, possible nodes are lymphatic capillary beds similar to bowmans capsule without rbc, rbc's supplied to the membrane of a node where the lymphatics diffusion in and out of the vessels like the surrounding vessels to a alveoli gland , specifically lymphatic vessels leading to the r. Atrium via vena cava and clavicle

[@TheNotedAnatomist]

Working on that now!

[@guytelfer1353]

​@TheNotedAnatomist , edited comment if you noticed, possible glands are lymphatic capillary beds transparent vessels, how about temporary micro capillaries considering a temporary barrier is built every menstrual cycle?

[@theopenacademy9102]

You’re teaching RN’s too!

[@rileysmiles]

i love my podocytes i think they are very cute heheh

[@edwigcarol4888]

35:00 🤐😁 mesanglial cells ... some signalling . Not sure to be able to simplify their complex tasks..
Won't speak about it 🤐😁.
Nature will overwhelm our understanding capacities.. as so often
I quote Peter Attia "the kidney is the smartest organ in the body"

[@TheNotedAnatomist]

That is what my nephrology colleague says all the time :)

[@guytelfer1353]

2 years?

[@Nikki-hl6zw]

@35:25…😳😂

[@benyoudr]

Thanks!

[@TheNotedAnatomist]

Thanks very much :)