Flexibility in definitions ! According to Fischer projection, groups attached by horizontal line are above the plane and those groups connected by vertical line are below the plane. But imagine what happens by rotating by 180 degrees or by making parallel transitions. Now groups above the plane are located below the plane and vice versa. So groups on horizontal line now are actually below the plane in original structure. So practically you can consider horizontal line either above or below the plane with vertical line in the opposite plane to it.
Thanks a lot 👏🏻👏🏻👍🏻👍🏻👍🏻i was just looking for d,l nomenclature for wedge dash i was solving just like you but was getting confused but now after seeing your example it is totally clear to me💯👍🏻. Thanks bro✅
I literally love you so much. I am starting my medicine at imperial this September and was asked to complete the primer. I was confused as to what the D and L isomers were and this video is the only one that actually helped me.
Sir OH group ko ap horizontal line pa q le k gaye?? Jo already group attach tha -CH2OH usi ki base pa q decide ni kar sakty k configuration D ha ya L???
I think if you count with the hydrogen or group that would let the most light into the rest of the molecule, facing forward, and then count in order of the groups with lowest to highest absorbance of higher energy (smaller wavelength) wavelengths in IR spectra clockwise or counterclockwise it works.
Sir, at 2:09 you mentioned information is wrong horizontal line indicates above the plane and vertical line indicates below the plane but you told reversed
In bahal and bahal book their is mentioned in fisher projection group on horizontal bonds come towards the viewer and on vertical away from the viewer it is opposite as u say. Pls check it .
By the definition, groups attached by horizontal line are above the plane and those groups connected by vertical line are below the plane. So whatever given in the book is correct. But it is highly flexible as we rotate the structure we can get the reverse. Those groups above the plane become below the plane and those below are now above the plane. It can also be observed by making parallel transitions. So we can consider in any way.
sir, with all respect,there is a mistake in your presentation at 2:05. that is,at vertical line the compounds are actually away from observer & at horizontal line the compounds are towards the observer . than you.if i am wrong, excuse me
Sir horizontal lines are above the plana a/c to fisher proj, u did mistake at 2.19,in previous vid u said that ,the horizontal line indicates grp above plane , in this vid u said horizontal grp are below
By definition, horizontal line above the plane and vertical line below the plane. But its highly flexible. If you rotate the structure it becomes reverse. horizontal becomes vertical and vice versa. So nothing different. It can also be even visualized by parallel transitions.
It depends on the type of substance and source. Many of the carbohydrates have D- configuration whereas many of the amino acids in our body have L-configuration.
Flexibility in definitions ! According to Fischer projection, groups attached by horizontal line are above the plane and those groups connected by vertical line are below the plane. But imagine what happens by rotating by 180 degrees or by making parallel transitions. Now groups above the plane are located below the plane and vice versa. So groups on horizontal line now are actually below the plane in original structure. So practically you can consider horizontal line either above or below the plane with vertical line in the opposite plane to it.
tremendous thanks, Indian professor saves the day 👏
What you said about fischer projection is wrong. Horizontal line is toward the viewer.
Thanks a lot 👏🏻👏🏻👍🏻👍🏻👍🏻i was just looking for d,l nomenclature for wedge dash i was solving just like you but was getting confused but now after seeing your example it is totally clear to me💯👍🏻. Thanks bro✅
May I know in which chapter this is in?
I literally love you so much. I am starting my medicine at imperial this September and was asked to complete the primer. I was confused as to what the D and L isomers were and this video is the only one that actually helped me.
Sir if solid line is on the left side, will it move to the right side in fischer projection or not?please tell, i am so confused.
Very helpful from the beginning!! Thank you!
Perfectly understood 😍thank you sir
Easily understood tq so much 😇
Very Good. Thanks
You are welcome!
nicely explained everything too much helpful thank you so much
Sir OH group ko ap horizontal line pa q le k gaye?? Jo already group attach tha -CH2OH usi ki base pa q decide ni kar sakty k configuration D ha ya L???
Very nice explanation 👍 Thank you, Sir.
You are most welcome
Best explained
You told to select the group in bottom most position. But doesn't that voilate the pronciple that the main functional group should be placed on top?
I think if you count with the hydrogen or group that would let the most light into the rest of the molecule, facing forward, and then count in order of the groups with lowest to highest absorbance of higher energy (smaller wavelength) wavelengths in IR spectra clockwise or counterclockwise it works.
Its very wonderful
For first example, we did rotation to get aldehyde group at top. Why now at 7:59 we do parallel transition
Highest oxicdsed group should be st the top. In first case it was aldehyfe and in this case it is COOH.
Sir, at 2:09 you mentioned information is wrong horizontal line indicates above the plane and vertical line indicates below the plane but you told reversed
Reverse is also true. Try it with parallel transitions. Thanks for paying interest on this video.
Thanks a lot Sir very nicely you have explained this 😊
Koi to video choda kr😏
Good explanation
Keep it up bro
Wish you a great success
(and)
Thankyou for making the vedio
Thank you.
Thank you, but isn’t 90 degree rotation not allowed mentioned in minute 8?
Sir this was the best explanation of any of all the topic that i have watched on UA-cam until now. Undoubtedly well explained sir. Thank you so much!
Omg any teacher can't explain me but because of these video I got it
In bahal and bahal book their is mentioned in fisher projection group on horizontal bonds come towards the viewer and on vertical away from the viewer it is opposite as u say. Pls check it .
By the definition, groups attached by horizontal line are above the plane and those groups connected by vertical line are below the plane. So whatever given in the book is correct. But it is highly flexible as we rotate the structure we can get the reverse. Those groups above the plane become below the plane and those below are now above the plane. It can also be observed by making parallel transitions. So we can consider in any way.
Excellent....
Thank you so much sir you have cleared all my doubt
You are most welcome
Educative
Many many thanks for this one sir
Most welcome!
Tq Sir,ur teaching is really excellent.
You're most welcome. Thanks for watching.
What to do if : 1) The Amount of OH right = the Amount of OH left ? 2) The Amount of NH2 left = the amount of OH right ?
In case 1, the carbon is no longer a chiral carbon. In case 2 we will give more priority to NH2 group and name accordingly.
@@vyomjoshi3013 yes having two same atom attached cause lost of chirality
Super mowa sir
TQ so much sir 🙏
even my allen teacher dint teach like this
sir,
with all respect,there is a mistake in your presentation at 2:05.
that is,at vertical line the compounds are actually away from observer & at horizontal line the compounds are towards the observer .
than you.if i am wrong, excuse me
Thanks for notifying. But the definition of Fischer projection is highly flexible. See the pinned comment on this video.
@@egpat thank you
Thanks a lot
Sir horizontal lines are above the plana a/c to fisher proj, u did mistake at 2.19,in previous vid u said that ,the horizontal line indicates grp above plane , in this vid u said horizontal grp are below
By definition, horizontal line above the plane and vertical line below the plane. But its highly flexible. If you rotate the structure it becomes reverse. horizontal becomes vertical and vice versa. So nothing different. It can also be even visualized by parallel transitions.
@@egpat ok , i got it sir!
Thanks u so much
Thank you
Amazing, thank you so much
You're very welcome!
Good explanation thanks a lot❤
Nice
5:20
conversion of wedge and dash projection to fisher projections
👏👏Super sir 👏👏
Thank you so much
Thank you ❤️❤️
Professor👏👏
Thanks man
Thank u
Thanks
Tq sir
I have an idea to improve your channel
Last 5 min
Try to give some examples to us
Say to keep the answers in comments
Sure, I will try to implement it in upcoming videos. Thanks for your advice and interest on this channel.
Sure sir
Which is more predominant? L or D?
It depends on the type of substance and source. Many of the carbohydrates have D- configuration whereas many of the amino acids in our body have L-configuration.
D
W teacher
L santha Kumar
First view
the sound is not good I am quite disappointed
ربي هو اني ممفتهمته النوب هندي ربي😭😭😭😭
Thanks so much