Imagining CRISPR Cures | Fyodor Urnov | TEDxBerkeley

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  • Опубліковано 23 сер 2024
  • Fyodor Urnov explores the future of CRISPR and how it has the potential to save lives. Professor Fyodor Urnov is a Professor of Molecular and Cell Biology at the University of California, Berkeley, and is a Director at its Innovative Genomics Institute, leading the Center for Translational Genomics and directing the Technology & Translation division. A pioneer in the field of therapeutic genome editing, Fyodor’s research focuses on advancing genome editing technology and pushing the boundaries of how it can be applied to solve real-world biomedical problems. In his work at Sangamo Therapeutics (2000-16), Fyodor and colleagues demonstrated the first use of native gene editing in human cells and coined the term “genome editing.” Fyodor then led collaborative teams to establish at-scale applications of genome editing for human somatic cell genetics and model animal and crop reverse genetics. Fyodor was a key member of the team that developed the first-in-human clinical application of genome editing (2009), and then led a from basic discovery to clinic an approach to use gene editing to treat the hemoglobinopathies, beta-thalassemia and sickle cell disease, that has resulted in sustained clinical benefit for over 70 individuals. At the IGI, Fyodor focuses on establishing turnkey editing of the human genome for clinical use and make CRISPR-based treatments for genetic disease broadly and equitably available on-demand. He works in collaborative teams to develop first-in-human applications of experimental CRISPR-based therapeutics for sickle cell disease, genetic disorders of the immune system, radiation injury, neuroinflammation, and neurological disorders. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at www.ted.com/tedx

КОМЕНТАРІ • 55

  • @robdev89
    @robdev89 10 місяців тому +4

    Every day my mind is blown by our Technologies and passionate people in the world, making these things possible. Thankfully the good guys do eventually find their way. 🎉

  • @bikojalal3120
    @bikojalal3120 Рік тому +27

    I have a son he has been diagnosis with Ethylmalonic encephalopathy disease which is less than hundred people in the world they have this disease. My son is four years and eight months old he is mildly affected. Our hope is this gene therapy will be available soon and it can save our sons life.

  • @esaiqwerty
    @esaiqwerty 2 роки тому +15

    Raise awareness. This is the future.

  • @maxthelionxmax9220
    @maxthelionxmax9220 2 роки тому +5

    This is excellent. No one knows who will develop a disease in the future. It’s important the solution is there before not after

  • @MrDigantvora
    @MrDigantvora Рік тому +5

    Thank you for information and bringing awareness of "Health Justice". Health justice is necessary because it, all we would be left with INFINITE GREED OF UNSUSTAINABLE HUMAN SOCIETY

  • @BearMeat4Dinner
    @BearMeat4Dinner Рік тому +3

    Dr. Doudna ❤

  • @rickidhal3950
    @rickidhal3950 Рік тому +2

    Thank you for championing the possibility of cure, I watched this with a ton of hope. I have to say your words are powerful but it's extremely hard to impossible to find anyone on this planet who can offer cure via crispr now. Just a bunch of videos saying we must do this. There are illnesses that can be cured now but it doesn't happen. Probably won't happen in the lifetime for many people dying right now. How do we really change this now?

    • @madhu_1489
      @madhu_1489 Рік тому +1

      They just advertise for to get investors attention. That all nothing more!

    • @PedroDeBandit
      @PedroDeBandit 10 місяців тому

      We hope that someone like Jeff Bezos comes to understand that he can't take his money with him 🙏

  • @lexwil1689
    @lexwil1689 Рік тому +1

    I am a dialysis patient and I know this would reverse the actions of kidney disease

  • @dancar2537
    @dancar2537 8 місяців тому +1

    we are going to automate medicine and this is going to get easy

  • @sanjaychoudhary8849
    @sanjaychoudhary8849 Рік тому

    Your speak made me cry at the beigning

  • @LuisOrtiz-ey1bp
    @LuisOrtiz-ey1bp Рік тому +3

    What about for autism and global development delays/disabilities?

  • @NicoleDaly-jq4db
    @NicoleDaly-jq4db 3 місяці тому

    Is CRISPR being studied for use in Familial Adenomatous Polyposis patients yet?

  • @squamish4244
    @squamish4244 10 місяців тому

    "O for a Muse of fire, that would ascend. The brightest heaven of invention"

  • @taylortischhauser4414
    @taylortischhauser4414 Рік тому +2

    Love the idea of CRISPR in a perfect world, but this brings up concerns and raises important questions about access and equity. If gene editing becomes widely available, it could create new forms of social and economic inequality, with only the wealthy and privileged able to afford the treatments and enhancements that come with CRISPR technology.

    • @juliahello6673
      @juliahello6673 9 місяців тому

      He literally just talked about how to make it affordable. I swear, Americans have watched too many movies and think that movie plots occur in real life.

  • @semrabahcivan8627
    @semrabahcivan8627 Рік тому +2

    I have Thallasaemia heterogeneous, Hyperthyroidism, Sjogren, autoimmune diseases, kidney stones, vascular retinal occlusion. Can I get any treatment ?

  • @charlesbaha5298
    @charlesbaha5298 Рік тому

    Wouldn’t this be easy to fix NF1?

  • @jaqueitch
    @jaqueitch 2 роки тому +1

    Indeed, Bluebird Bio is bound for bankruptcy

  • @akhiy5384
    @akhiy5384 Рік тому +1

    I have PTSD and i want to erase my trauma .i don't my future children to not have any kind of disease😭

    • @lucid0443
      @lucid0443 Рік тому +2

      i hope you’re re joking

  • @johndaly6497
    @johndaly6497 2 роки тому +1

    Need allogenic options.

  • @srin8116
    @srin8116 Рік тому +1

    👍

  • @YouTube_Enjoyerlol
    @YouTube_Enjoyerlol Рік тому +1

    I just want to genetically engineer myself to stop aging after the age of 25 😆 👌 let’s gooooo

  • @nmbr1ctrman
    @nmbr1ctrman Рік тому +5

    Weaponizing Crispr seems to be a big issue in the future as well

    • @religionisapoison2413
      @religionisapoison2413 Рік тому

      Yeah like editing a SARs virus..... And making billions of dollars for you and your buddies while it spreads around the world

    • @questmarq7901
      @questmarq7901 Рік тому +7

      This is the last of our problem. We need gene therapy asap

    • @nmbr1ctrman
      @nmbr1ctrman Рік тому

      @@questmarq7901 won't matter if someone creates a super virus and destroys humanity.

    • @sanjaychoudhary8849
      @sanjaychoudhary8849 Рік тому +1

      ​@@questmarq7901 so true

  • @OneOfMany111
    @OneOfMany111 Рік тому

    👽♥️🕊️

  • @lttrhd
    @lttrhd 11 місяців тому

    What about a schizophrenia?

  • @PedroDeBandit
    @PedroDeBandit 10 місяців тому

    Jeff Bezos... are you listening...

  • @jebediahconde2143
    @jebediahconde2143 2 роки тому

    Can we crisper out the speakers mouth noises?

    • @aj-uo3uh
      @aj-uo3uh 2 роки тому +1

      Can we crisper out you?

    • @jebediahconde2143
      @jebediahconde2143 2 роки тому

      @@aj-uo3uh nope. Here to stay

    • @aj-uo3uh
      @aj-uo3uh 2 роки тому

      @@jebediahconde2143 Ok fine, please behave then.

    • @lttrhd
      @lttrhd 11 місяців тому

      The topic is too serious to concentrate on speaker noises

  • @imagreatguy1250
    @imagreatguy1250 2 роки тому

    This is the 4th comment. Shit's RARE...

  • @completelybraindead
    @completelybraindead 2 роки тому +1

    This guy needs a glass of water or something. His mouth sounds dry af.

  • @yvonnecarter4118
    @yvonnecarter4118 Рік тому +1

    Stop swallowing into the mike. It sounds dreadful and prevent me from listening 😢

    • @lttrhd
      @lttrhd 11 місяців тому

      Turn off sound, turn on CC

  • @Hunter_Bidens_Crackpipe
    @Hunter_Bidens_Crackpipe Рік тому

    I can’t deal with the lip smacking. I want to watch this but it’s to much to handle

  • @documentedrecords5364
    @documentedrecords5364 2 роки тому

    Imagine.......CRISPR CURES!.....
    Me: Yeah, keep imagining idiots

    • @JZGreengo
      @JZGreengo 2 роки тому

      It’s like call of duty releases, im not hyped for the next one and I’m most likely not hyped for this, im not crashing on that train like the stem cell one