Coming back here after i got my first job as a doctor, i can't believe so much time has passed since i was worried about my biochemistry exam. i remember watching these videos and knowing your voice so well. just a reminder that what seems to be the biggest hurdle in your life right now may be an insignificant detail years later. thank you for everything.
Thank you very much for all the time you have spared to make these videos. I really appreciate the work you've put into them. Since I am a Biotechnology student and take courses in Biochemistry, I can openly say your videos have been the most easy to understand source of information. Much better and more interactive than reading Lehninger!!!
you are officially the best. i have had all my friends check your channel and they loved it just as much. your methods and how neat you are, it is so satisfying to the brain. THANK YOU
I have a glycolysis quiz in 2 days and I need to remember every single step and product and enzyme used to catalyze each rxn. Watching this video is helping me UNDERSTAND the content which is definitely a lot more useful than just straight memorization! Thanks!
Probably the best explanation for Glycolysis. What matters the most is clarity of the facts, articulation and ability to make the concept understandable. You are too good.
These videos are amazing if you have a basic grasp on the material and you want a thorough explanation. The fact that you break Glycolysis into three sections is awesome, because it not only really gives you the purpose but it also doesn't overwhelm someone like looking at a massive chart of info
do you ever feel like you're going to pass out from talking for 15 minutes without pausing to breathe? It is fascinating to watch how naturally you talk and talk, hopefully I'll be able to do this one day, just have to keep practising not pausing for a breath whilst talking for now on LOL
16:06 When your favorite TV show ends it's season on a cliffhanger Sorry for the joke .-. your videos are great! I love learning about biology and biochemistry!
omg!. I have learned this material in three classes now (biology, microbio, and biochem), but I have not truly understood the process and WHY there are so many steps. I just memorized the process. These videos have helped tremendously! Thank you so much. I wish I would have stumbled upon these videos sooner.
I CAN'T EMPHASIZE ENOUGH HOW GOOD YOU ARE. THANK YOU SO MUCH FOR EXPLAINING DOWN TO VERY SMALL DETAILS. YOU TEACH IT IN A WAY LIKE NO OTHER, NEAT, CLEAR AND CONCISE. BUNCH OF THANKS.
My friends recommended I watch your videos to get a clearer understanding of biochemistry and to be honest, I am not disappointed at all. Thank you so so much for the concise explanations
your videos are great. you know how to simplify complex material and explain it clearly, I have been watching your videos throughout university and not only do you teach well you also teach many subjects. great job!
Wow.. thank you so much.. your lectures help me comprehend this topic perfectly.. I’m having my biochemistry test in 2 days and your lectures are simply helping me to secure a better future for myself just by acing this test. Lots of appreciation and respect towards you.
Excellent video. I just have one question though. In Step 6, where does the other H+ ion come from? I see one H being transferred from the GAP to NAD but I'm not sure where the other H+ in the products come from
In step number 7 I dont think there is supposed to be an H+ in the reactants because the mechanism is a substrate level phosphorylation. It should read 1,3-BPG + ADP ---> 3PG + ATP but correct me if I am wrong
Why wouldn't it do so though? Asking because I'm dumb and need a more thorough answer besides "substrate level phosphorylation" Edit: Actually yeah, I think I see the lack of a need for a H+ there.
you are the best lecture I love you.... I like when you explain why is a certain reaction is necessary this gives me energy to learn it quickly.....I love you so much
Thank u so much for your effort.. would appreciate it a lot if u attach a picture of the board with the vid or at least dedicate the last second of the video to show the entire board so we could capture it.. I'm a medical student and i use these videos to study biochemistry so it would help a lot to keep the pic for review and to look at it while i study through my lecture.. thank you again ❤️
Thank you for your awesome lectures, they have helped me a lot in understanding these processes. You are really clear and good at explaining :) About step 8: my teacher in biochemistry told us that the enzyme phosphoglycerate mutase already has a phosphate group attached to itself, and uses this in the reaction. This suggests that i'ts not the same phosphate that "moves around" on the 3-phosphoglycerate molecule to create the 2-phosphoglycerate molecule, it's a "new" one donated from the enzyme phosphoglycerate mutase. What do you think about that? Thank you once again! Best wishes from Sweden
Could you explain to me why it will be formed 2 molecules of H+ in the net final result? I tried to calculate it, but I got 0 molecules of H+ your lectures are great, thanks a lot!
Is there a difference between PGAL and GAP or are the interchangeable terms? In your Glycolysis vid you use PGAL for steps 4,5, & 6 but here in this overview vid you use GAP.
Hi, thank you for the great video, I have a question, Whats the ratio of oxidized NAD ( during glycolysis and gluconeogenesis)to reduced NAD in mitochondria ?
Coming back here after i got my first job as a doctor, i can't believe so much time has passed since i was worried about my biochemistry exam. i remember watching these videos and knowing your voice so well. just a reminder that what seems to be the biggest hurdle in your life right now may be an insignificant detail years later. thank you for everything.
This is awesome and really inspiring! I’m currently doing some last minute reviewing for my MCAT in 2 days
Any advice for 1st years? Also is this biochem stuff useful in your job as a doctor?
@@WQR2 It sure is Important for your GPA and yes I think its importance depends on which field you choose
Preparing for a Biochem exam using this video - headed to Dental school
I can't fathom how many tests and GPA's AK has saved with these videos.
I'm a medical student. I really appreciate your videos, so clear and concise!
+Summerbreeze thanks !
Me too!
nine years later and your still helping out the next generation of college students!! Thank you so much!
Thank you very much for all the time you have spared to make these videos.
I really appreciate the work you've put into them.
Since I am a Biotechnology student and take courses in Biochemistry, I can openly say your videos have been the most easy to understand source of information. Much better and more interactive than reading Lehninger!!!
I am also a biotech student, cheers
startouchers and
startouchers
Hey I am a biotechnology student as well
Me too
Same!!!
I just want to say that I love you.
you are officially the best. i have had all my friends check your channel and they loved it just as much. your methods and how neat you are, it is so satisfying to the brain. THANK YOU
Best overview of glycolysis on the internet: clear explanations of the processes involved
I have a glycolysis quiz in 2 days and I need to remember every single step and product and enzyme used to catalyze each rxn. Watching this video is helping me UNDERSTAND the content which is definitely a lot more useful than just straight memorization! Thanks!
Probably the best explanation for Glycolysis. What matters the most is clarity of the facts, articulation and ability to make the concept understandable. You are too good.
I love when he says ''Why?'' after explaining a stage, incredible teacher.
You sir, are saving lives.
You're a legend ! Biochem seems so easy with your lectures :-)
These videos are amazing if you have a basic grasp on the material and you want a thorough explanation. The fact that you break Glycolysis into three sections is awesome, because it not only really gives you the purpose but it also doesn't overwhelm someone like looking at a massive chart of info
do you ever feel like you're going to pass out from talking for 15 minutes without pausing to breathe? It is fascinating to watch how naturally you talk and talk, hopefully I'll be able to do this one day, just have to keep practising not pausing for a breath whilst talking for now on LOL
What I like about this channel and its videos is that, it makes the complicated concepts much more easier to understand.
Thanks a lot AK Lectures.
16:06 When your favorite TV show ends it's season on a cliffhanger
Sorry for the joke .-. your videos are great! I love learning about biology and biochemistry!
omg!. I have learned this material in three classes now (biology, microbio, and biochem), but I have not truly understood the process and WHY there are so many steps. I just memorized the process. These videos have helped tremendously! Thank you so much. I wish I would have stumbled upon these videos sooner.
I swear this guy is legit the BEST instructor out there. Thank you for your videos!
Thank you ! I memorized these many years ago without knowing the purpose of each step! You are a great teacher! Never forget this pathway
Thanks
you’re the best I swear
See even after 3 years we still watching your videos
I CAN'T EMPHASIZE ENOUGH HOW GOOD YOU ARE. THANK YOU SO MUCH FOR EXPLAINING DOWN TO VERY SMALL DETAILS. YOU TEACH IT IN A WAY LIKE NO OTHER, NEAT, CLEAR AND CONCISE. BUNCH OF THANKS.
you helped me through genetics and now biochem. thank you
My all time favourite...continue serving us
I just used Y=MX+B for each step. Worked like magic. B= Glucose. MX= Enzyme Action. Y = Output.
Step 1. Glucose-6-Phosphate = Hexo-Kinase+ Glucose.
Step 2. Fructose 1.6 Phosphate= phosphogluco Isomarase + Glucose-6-phosphate.
Step 3. Fructose 1.6 BiPhosphate = Phosphofructo Kinase + Frutose1.6 Phosphate
Dental student here. You're helping me survive. Thank you so much
You are absolutely the best! Everything is explained so well!
thank you thank you thank you thank you forever and ever. this LITERALLY saved my life. You are AMAZING!
thank you - brilliant as always
he makes everything so easy
U R the best teacher that I have ever seen! Tnx a lot
thank you so much for making all of these videos. I'm a nutrition student and these videos are really helping me. thank you. thank you very much :)
N K to become a Registered Dietitian. Prereqs are biology, microbiology, a&p 1 and 2, gen chem 1 and 2, ochem, biochem.
@N K yes! nutrition has a biochemistry and even on 1.200 pages. Now you know 😉
My friends recommended I watch your videos to get a clearer understanding of biochemistry and to be honest, I am not disappointed at all. Thank you so so much for the concise explanations
You, sir, are a genius. Thanks for all your help.
incredible work, sir :)
your videos are great. you know how to simplify complex material and explain it clearly, I have been watching your videos throughout university and not only do you teach well you also teach many subjects. great job!
Wow.. thank you so much.. your lectures help me comprehend this topic perfectly.. I’m having my biochemistry test in 2 days and your lectures are simply helping me to secure a better future for myself just by acing this test. Lots of appreciation and respect towards you.
You are the greatest teacher ever!!!!!...Thank You so muchhhh
very intellectually talented. one of the greats. I love your videos, they're getting me through the MCAT. Thank you
youre god-sent. thank you for helping me pass.
Thank you so much. This Lecture is so helpful.
This waz just your summary and for me this was more than what i needed ....Loads and loads of love to you.
#AGreatSaluteToYourHardWork❤
You are a fantastic teacher, thank you!
I’m medical student l really appreciate your work thanks a lot ♥️💁🏻♂️
Excellent video. I just have one question though. In Step 6, where does the other H+ ion come from? I see one H being transferred from the GAP to NAD but I'm not sure where the other H+ in the products come from
back in college, I never appreciated AK cuz he takes forever, but now that I'm studying for the MCAT, I consider him to best.
so clear,thank you
Thank u 💓 from 🇪🇬 Egypt u are excellent
In step number 7 I dont think there is supposed to be an H+ in the reactants because the mechanism is a substrate level phosphorylation. It should read 1,3-BPG + ADP ---> 3PG + ATP but correct me if I am wrong
Why wouldn't it do so though? Asking because I'm dumb and need a more thorough answer besides "substrate level phosphorylation"
Edit: Actually yeah, I think I see the lack of a need for a H+ there.
He explains that in step 10, H+ must be present along with ADP so the phosphoryl group can leave from the molecule... I think.
thank you you absolute saved my quiz!
Thank you so much for the in-depth and clear explanation. I'm a brewing student and glycolysis has been so confusing to learn
I thank you so much right now. My biochem exam is in two days!
Your lecture has greatly helped me in food scince
Now I understand glycolysis. Thank you Sir
I just found this guy. He's an Angel 😌🙏
Oh My God, thanks for the video, you've really saved me.
you are the best lecture I love you.... I like when you explain why is a certain reaction is necessary this gives me energy to learn it quickly.....I love you so much
thank you for these inputs...very interesting compelling to watch and easy to understand
You're a life saver.
Thank you, very easy and informative
I LOVE YOU SO MUCH!!!!! from opposite site of earth!!! thxthxthx!!!!
Thank u so much for your effort..
would appreciate it a lot if u attach a picture of the board with the vid or at least dedicate the last second of the video to show the entire board so we could capture it..
I'm a medical student and i use these videos to study biochemistry so it would help a lot to keep the pic for review and to look at it while i study through my lecture..
thank you again ❤️
Maya Mahmoud pause at 15:19
Nice explanation. It would be more useful if you could add inhibitors of glycolysis as your lecture gets registered very well.
damn i went from not even knowing the results of glycolysis to understanding the whole reaction from this lol
Thank you for your awesome lectures, they have helped me a lot in understanding these processes. You are really clear and good at explaining :)
About step 8: my teacher in biochemistry told us that the enzyme phosphoglycerate mutase already has a phosphate group attached to itself, and uses this in the reaction. This suggests that i'ts not the same phosphate that "moves around" on the 3-phosphoglycerate molecule to create the 2-phosphoglycerate molecule, it's a "new" one donated from the enzyme phosphoglycerate mutase. What do you think about that?
Thank you once again! Best wishes from Sweden
thank u very much sensi!
+محمد عاصف welcome!
i m a student... i would like to say tht ur xplanatns r awsm...
Incredible!
Brilliant explanation
You are excellent. Thank you.
Switched to an ad right at 16:06 lmao
"And the net output is - RAID SHADOW LEGENDS"
I just gotta say Thank you! I was so confused on this topic.
You are a god among men.
Thank you very much,,
i have a question
in the glycolysis process has 3 irreversible steps,, could you tell me what steps are they, please?
+Hussein II It's 1,3 and 10. 1) Glc -> Glc-6-P. 3) F-6-P -> F-1,6-BP 10) PEP -> Pyr
Brilliant . Thank you so much 🤞
Amazing work sir , u r superb
Lifesaving videos!!
You're amazing, I wish you were my professor :(
what an absolute god
thank you :)
Could you explain to me why it will be formed 2 molecules of H+ in the net final result? I tried to calculate it, but I got 0 molecules of H+
your lectures are great, thanks a lot!
Love these videos so much! Also FYI I am not able to load the website.
Student from all over the world should pay their tuition fees to this great man! **You can't change my mind**
Should we put the energy written below the arrows on the right sides of the reactions？
THANK YOU SO MUCH!!
Thanks you are awesome!
You are great man
you are awosme, many thanks
very very helpful thank you
You are geniuses
Is there a difference between PGAL and GAP or are the interchangeable terms? In your Glycolysis vid you use PGAL for steps 4,5, & 6 but here in this overview vid you use GAP.
All hail Andrey K, king of all life sci students!!!!
Well explained
thank you
+Peter Ridge you're welcome!
Lifesaver🙌
that cliff hanger tho lol thanks for all the studying you saved me
thank yu very much
Where does the water molecule go that was produced in glycolysis? Is it used in Kreb's cycle?
Thank you.
Hi, thank you for the great video,
I have a question,
Whats the ratio of oxidized NAD ( during glycolysis and gluconeogenesis)to reduced NAD in mitochondria ?