Celiac Disease (& Gluten Sensitivity): Risk Factors, Pathogenesis, Symptoms, Diagnosis, Treatment
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- Опубліковано 8 чер 2024
- Lesson on Celiac Disease (and Gluten Sensitivity) and related health effects (including skin lesions, osteoporosis, infertility etc.), along with risk factors (genetics), pathogenesis (autoimmune), symptoms, diagnosis and treatment. Celiac disease is an autoimmune gastrointestinal disease that leads to inflammation and destruction of intestinal villi and microvilli, ultimately leading to malabsorption. Diagnosis involves checking for serum autoantibodies along with small bowel biopsy, and treatment involves strict dietary adherences.
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**MEDICAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal.
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JJ
For more information on conditions associated with Celiac disease, please check out these lessons as well.
Sjogren’s Syndrome: ua-cam.com/video/FAspQVAJUto/v-deo.html
Graves Disease: ua-cam.com/video/IjAeZZWBHm0/v-deo.html
Hashimoto’s Thyroiditis: ua-cam.com/video/ZaxjJ_c0J6o/v-deo.html
Major Depressive Disorder: ua-cam.com/video/2dSQV6ZMbl0/v-deo.html
if someone has Celiac Disease and make Serology testing for antibodies and came positive but then after doing Genetic testing for human leukocyte antigens (HLA-DQ2 and HLA-DQ8) and cames as negative for both DQ2 AND DQ8 ?
does that mean? he has celiac disease?
@@PatriotSouls that means he has a gluten sensitivity that is not associated with those genes.
I have iron deficiency all my adult life. Constant diarrhoea, Sjogrens Sydrome and Hasimotos. My NHS doctor scoffed when I asked for the test and said it was unnecessary to start eating Gluten. Cambridge educated too 😢
When i was diagnosed with celiac, I was overweight, and always severely constipated, since I could eat solids. It took 30 years to get a diagnosis, after many misdiagnosis through my life. I was laughed at my doctors when I was 4 years old, they asked my mother if she knew what was causing my constipation, I said it was bread that does it. They laughed and one said “ don’t be silly, bread can’t do that to you”. So after that comment by that doctor, I never told my mother what was wrong with me. I got by not eating or wanting any sandwiches or desserts. As soon as I turned an adult I finally got a diagnosis, I went 100% gluten free and never wanted to see another doctor again.
I wish people were more respectful to children. I'm sorry that happened to you.
Those doctors are under hypocratic oath to do no harm.... to ignore your comments is criminal... totally get why you have no wish to see one ever again. We feel the same
Did you have chronic widespread pain with a gluten diet?
@@jeanettemorrell3693 From my intestines down I do.
I was made fun of too as an adult in my thirties and never thought that what I am going thru is not normal.
This man knows what he’s talking about, he’s nailed Celiacs disease. Thank you .
Thank you for helping me understand my chronic illness. I wish there was more information on this illness. It's scary not understanding what going with your body.
I just went for a colonoscopy and gastroscopy. I was told to refrain from food with gluten. It has only been a week but this really helped me understand.
The problem is when the society around won't believe/understand this problem even when you explain this to them they would just think that you are just overthinking things and that it would go away and not get worse
I was diagnosed with Celiac Disease 15 years ago. It took almost 2 years to diagnose. A dietitian told the doctor to test me for Celiac Disease. All the tests I had to go through before the diagnosis.
Thank you for the decent and reliable contents.
Thank you for making this easy .
thank you so much this was very informative!
Thank you for the great video🙏🏾
Great and outstanding work thank you very much for making the subject easy and full of information
You're very welcome! Glad it wasn't too too much information :)
Really outstanding , i’m very grateful 🌷🌷
You are a really great teacher 💯✔️
Thanks for the helpful information
My son is 3 years old and his doctor just called me saying that he has signs of celiac and I have to go to a specialist now so I’m a little worried but this video really helped me understand a lot of things.
@@notebook2876 Not true at all. Most cases of celiac disease can be managed well simply by avoiding gluten in the diet. People with celiac disease live normal, healthy lives. Please do not go around the internet scaring people for no reason.
@@notebook2876 bro I have it and it’s not that bad u just can’t eat to much gluten
@@notebook2876 😁 idiot.
@@plaz4481 "u just can’t eat to much gluten". If you have celiac and not just gluten sensitivity then you should eat 0, zero, no gluten. Everything above 0,02 g (a grain of sand of gluten) is causing an autoimun reaction in the body. My girl friend has celiac and she eats zero gluten for now 2 years. She ate by mistake something which was prepared on a gluten contaminated wood plate and directly the number of antibody from her blood test increased from 50 to 1000+ (Everything below 50 is ok). Thats why celiac people can not eat in restaurants if there is a risk of contamination. Its not like lactose intolerance or a nut allergy. It doesnt matter is you consume 0,02 g or 1 kg of gluten. The antibody reaction is the same. Not the gluten is causing the problems, the antibody reaction caused by gluten is the problem
@@plaz4481 I have celiac disease, I can’t touch gluten. I’ve been accidentally gluten when eating out, and I can’t leave the house for days. I’d never deliberately eat gluten, not one crumb.
You have no idea how much you've been helping me get through PA school... Please consider making a podcast (not about medicine tho lol)... you're voice is gentle to the ears...
great teacher
Thank you so much for the perfect explanation👌👌👌👌👍👍👍👍👍🙏🙏🙏🙏🙏🙏🙏
Thank you ☺️
Great info 👍
Thank you, this video is 3 years old, I only recently came across it. Its excellent. and it’s helped explain so many side effects of CD, things I’ve suspected. Then you hear it from an expert in the field of CD, all of a sudden it falls into place.🤷♀️
CAC Curcumin capsule is prepared from the herb turmeric. The herb turmeric (Curcuma longa) contains the active compound curcumin that shows antioxidant, anti-inflammatory, analgesic, & immunomodulatory properties. These properties deal with the pain in abdomen, loss of appetite, indigestion, & improve overall digestion. It helps in building up the immunity of the small intestine to deal with the coeliac condition.
thank you
Found your channel searching for videos on the novel Coronavirus, and I really like how informative your videos are. You’ve gained a new subscriber. I have Celiac disease myself, I’ve had it for 13 years now, since I was 13 years old. Interesting what you said about it being associated with other autoimmune conditions, as I also have Grave’s disease.
Hi Morgan! Thank you so much for your comment! I'm super happy that you found my channel helpful and informative. Yes, celiac disease is associated with autoimmune thyroid conditions (both Grave's and Hashimoto's), which I wish I had discussed more in this lesson for you. :) Let me know if you have any other questions. Take care.
Thank you.
You're welcome! :)
Too Many poor medical student from developing countries greatly benefit from your free but extremely valuable work. My way to pay is to ask God's forgiveness, mercy and heaven for you and your respective parents and family as well as any one you love or loved you.
It took 6 months with a strict gluten free diet for me to notice a difference. Had I given up after just 3 months, I would have not received the correct diagnosis.
Mashallah very informative 👌🏿😇❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️
Celiac is not diagnosed when i tested from laboratory. But i can not drink and eat properly. There is lot of stomach pain and pain is relieved when i eat something, then motion start. The pain is worse between meals and night. When i eat rice i feel relaxed but lot of rice leads to asthma at night.
Also I have gluten sensitivity enteropathy but I'm bakery chef I don't eat anything but I want to work only please give me answers
if someone has Celiac Disease and make Serology testing for antibodies and came positive but then after doing Genetic testing for human leukocyte antigens (HLA-DQ2 and HLA-DQ8) and cames as negative for both DQ2 AND DQ8 ?
does that mean? he has celiac disease?
thank you! Im 15 and I was diagnosed with celiac disease after I broke my arm for the 6th time.
Hi blue! Thanks for the comment! Sorry to hear about that. I hope you're feeling better :)
Constipation is a major system too
PTH high and VitD extremely low with Normocalcemic levels. I was thinking calcium would present as normal in the presence of height PTH later on in a Celiac related deficiency, no? Due to the body wanting to break down the bone to create more calcium levels in the blood? But then even later it can no longer keep up and therefore blood levels of calcium decrease again?
Also, many people with celiac are actually overweight because the malabsorption makes them feel hungry constantly so they often over-eat and eat calorically dense foods? And I’ve read that some celiac patients have alternating diarrhea and constipation because the intestine absorbs more water due to digesting foods in the colon that were left undigested higher up. -creating constipation due to dehydration?
I mainly had constipation but still had huge weight loss. Not three years and still tired but I am better and on vitimains daily with strict gluten free diet.
Also do you think a diet you had early as a child for me lots of sugar and wheat base products and woth poor eating habits could trigger something?
Can you help me about diet?
I’ve had it since a was in my moms stomach she could not eat anything when she was pregnant with me I’m 21 now and it hurts like crazy when I accidentally eat something feels like I’ll die 😭😭😭
Another symptoms involves the teeth: they are noticeably darker and can have spots on them (my top front teeth both had white circles on them), they can decay differently (I have had 3 rot from the inside out and so don’t show as bad on X-rays), they get deep cavities more easily and quickly, and just get infected easily. Half my mouth has crowns or bridges, including those front teeths’ enamel that actually slivered off by layers (once when I was eating a nectarine).
I disagree, its a neurological autoimmune condition. Most often in conjunction with blood mutation MTHFR which increases malnutrition and vitamin and mineral deficiencies as well as de-myelization of the myelin sheath around all the nerves in our bodies. Often Celiac's are overweight due to a lack of metabolic function and constipated, not always suffering from diarrhea..
I have a hard time losing weight. Have you found anything that can help with that and help our metabolism? I never had pro lems losing weight before. I have always been able to lose it fast. Now I eat a fruit in the morning and don't eat anything until dinner and still can't lose weight. My hair has also changed and has become brittle at the ends and break. My hair grows almost 2 inches a month but it never seems to get lo get and I assume it's because it's been breaking. I'd like to know if there is any help for these
De-mylation suggests multiple sclerosis.
That was me. Cronic constipation, arthritis in the knees, weight problems over time, etc. The problems started at age 5. Maybe younger, but as far as I can remember the problems. Finally diagnosed at 48.
@@dawnelder9046 Yes for weight loss eat Grain Free as corn, rice and other grains all contain forms of gluten or gluten mimicking proteins. I eat low carb and I've lost over 35 lbs. Reach out if you wish at Celiac Revelation here on youtube. Best of Health and Happiness to you in the New Year!
endomysial abs iga was positive
Tissue transglutaminase IgA positive with a value of 1.0 only above the standard range.
I had Brucellosis at the time these tests were taken. Doctors ordered these tests because of my severe belching.. some said it was anxiety, others stated it was celiac based on the results
I have NONE of these symptoms. None. Just recent weight loss ( but I am doing intermittent fasting and calorie watching) and a mild but annoying, and discomforting tingling headache in one spot in my head that occasionally occurs ..mostly at night after spending a long time on the phone/laptop.
My daughter is 7 year old and she is having a test to see if she has Celiac 😞 she came positive on autoantibodies
I just got results back from 23andme that I carry both of the genes for celiac, I have a long history of stomach and digestive issues.. how likely is it that it can be due to celiac?
hahaha just got to the point of malabsorption... vitamin d diffiecieny. I am very deficient in vitamin d, its almost non existent. my doc said its dangerous. im at 13
omg and now I see them saying dermatitis herpetiformis and I just got some type "eczema" like skin condition.
I’m 62 yrs young. I have been suffering from skin disorders, HS, leaky gut, depression, etc. I have always suffered from diarrhea constantly. I went on the keto diet, lost 25 lbs. I felt great, but the skin condition still comes on and so does the diarrhea. I had both small intestine and a colonoscopy done & everything was fine. Then what the heck is wrong with me???
This is the age where some thing goes wrong without any clues,Try to eat clean and excercise daily.Do meditation also for depression.Take ViT-D shots once a while.
Get the antibody test. How are you now?
Look for sifo/sibo.
I'm 58. Had the same symptoms as you. If you have a skin condition, you have a super risk of being diabetic or prediabetic. Once I got off sugar, my skin cleared up......only took a couple weeks.
Try going carnivore for two weeks and add back one real food a week. If itbis made with grass, it is not a real food.
Doctor recommended me to eat oats as long as it is not been handled in the same mill/location with the other grains. Is that total BS? Or is there just a lower count of gliadin ?
'as long as it hasn't been handled in the same mill etc' ... Good luck trying to verify that, even when the packaging suggests it - there's a lot of overlap in the supply chain of all those grains. As well as that, co morbidities occur with celiac, oat sensitivity can be one of those things. You're just better off not risking it, but common wisdom suggests that going gluten free - including oats - for a long, long time (a couple of years) - is a good idea before introducing a 'trusted' source of oats in small doses, if you really must, and see how you get on.
are you a practicing physician? If so if you are taking new patients? Locaion?
hi, i have it ...its been a couple of years ..im 32 years old and i dont know how to gain kilo? i workout..i take care of everything i eat but i dont see changes on my body.. 😔
How are you now?
@@enriqueecheverria8592 im ok mate,thanx. what about you?
@@johnjohni7779 I am living with ciliacs the best I can I guess. I was recently diagnose last April. I deal with a lot of cramping, gas and sometimes confusion. Whe. I see other I feel this need to reach out. I dont know anyone with this disease and didnt realuze how serious it is. I mean it even reduces our life expectancy. Wild. I wish there were chanells on youtube for people like us.
@@enriqueecheverria8592 i hope you ll be ok . take care of you ,take care of the food you eat. for me is about 10 years now living with that
It's never going to happen. I've had celiacs my whole life the worst case they seen (I'm in a medical studies book it was that bad 🥴). We never gain weight because we can't digest food properly therefore our body can't get the calories from the digested food. We are doomed with skinny bodies forever. You can tone what you have but you'll never be a bodybuilder. Sorry 😔
Living with the stigma of HSV 1 & 2 and not been able to have a healthy relationship was messing up my life until I got some super herbs from Dr igho UA-cam channel, I haven't had any Symptoms for some while now, after I did a test & I'm planning to get another test done. Am grateful & advise you help yourself also
I tested HLA-DQ2 and DQ8, yet camera down the throat showed mucosal changes but no conclusive evidence of being coeliac. My sister has Hashimoto's. I have all the signs. Doesn't make sense why the camera down the throat would show inconclusive.
If you have the signs (high ttG and positive EMA) then go gluten free regardless of the inconclusive biopsy. Left untreated, celiac disease can kill you via stroke, heart attack or cancer. It's a shame he did not cover this aspect in his video. If the blood tests are negative you might still have non-celiac gluten sensitivity.
@@SeanFication thank you. Yes I pretty much am gluten free. I mostly eat fresh fruit and vegetables only, my diet has just adjusted to crave that only. With a bit of lean meat now and then. Strange I had both those markers but two inconclusive endoscopes. I can only think that I didn't finish the gluten challenge and eat 8 weeks solid of high gluten as it made me too sick? Either way, going gluten free is definitely best
I see this was 3 years ago well its out of date by 40 years.
What if you are born with it like me and none of your family members or past family members have celiac disease (I’m 15)
Welcome to the club. Parties are very boring bring your own food 😂
Gluten free diet is not helping me...stomach is swellen with gas..any celiac patient feel the same? ?
Hi. My endoscopy and blood work all negative. But I have many of the symptoms. My biggest complaint is swollen belly and stomach. So I took it upon myself to begin a gluten free and dairy free diet. No improvement either. And I’m being very strict diet
Had to remove all grains and dairy and sugar to start to feel relief...not just gluten.
I got better in only not even 2 days after stopped eating white bread.
Should I be concerned or just continue?!
Have you been tested for celiac ?
@@hotbuttered7711 No...but I don't think that I have *celiac* ...Because I moved in another country for like 3 months now and I can eat bread without issues...
I watched some other videos on YT and I think that I had/have some mold infection... because that doctor on YT said that usually people with mold infections get much better very fast after they stopped eating foods that get moldy very fast...like grains.
I had/have mold in the room where I spent a lot of time in the last year (i was basically a hikikomori)...but I also had/have mold in that wood thingy...where you keep the bread.
@@azumag4432 a
My bowel movement are too fast, also my urine and poop feel too acidic. i have poor apetite
Have you talked to your doctor about this? If so become louder in making your point that this isnt going away and would like to test for things or get a referal to a gi doctor. How are you now?
@@enriqueecheverria8592 I feel better now. Bread was killing me!! im alergic to gluten. this is my my first week going glutten free. i feel better , no more acidic urine , poop stil a little acidic but just a little. my appetite has increaseed. i cant belive it was bread that was taking down. im so glad i found out the problem ☺but no more pizza or cookies. or burrtos but its ok😏
Dang. That's good you figured it out. Took me years. I ended up being diagnosed with ciliacs disease. It's much more serious than most people think. It can lead to a shorter life expectancy. Have you thought about getting the blood tests for it?
@@enriqueecheverria8592 maybe , in the future, did yu get one?
@@JavyM yes I got the blood tests. It's really easy and quick to do.
Buckwheat ok to eat ?
Yes, it is ironically gluten free. Watch out for barley though.
Every celiac should give hookworms a try.
You need to update your reading on celiac ... There's more people overweight than underweight when diagnosed. Pushing this out dated idea about being underweight (with no caveat or qualifier) will give false confidence to overweight and as yet undiagnosed celiacs.
It’s the worst
kidney
HOW COULD WE UNDERSTAND YOUR MEDICAL TERMS ONLY MEDICAL PROFESSIONALS CAN UNDERSTAND YOU
Sir i have celiac disease and suffering from lack of sleep is this normal?pls reply🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🏻