You are a tremendous help to everybody studying chemistry!!! Please don't stop doing what you're doing because we are extremely grateful!!! You are saving us lots of tears, sir!
This is a really great, informative video! I was having trouble finding one so detailed on this specific topic, you made it really easy to understand. Thanks so much!!
Not necessarily, but possibly. At physiological pH, there are thousands of protons in a given cell that can be gained from solution hydronium ions. While it's possible that that one proton is the same, there are much higher odds that the transferred proton is simply lost to solution and a different one is regained. If you're trying to trace individual protons, for example by using deuterium labeling, you would end up with a rather low level of incorporation.
You are a tremendous help to everybody studying chemistry!!! Please don't stop doing what you're doing because we are extremely grateful!!! You are saving us lots of tears, sir!
This is a really great, informative video! I was having trouble finding one so detailed on this specific topic, you made it really easy to understand. Thanks so much!!
Thank you for posting this mechanism, these things are sometimes hard to find for biochemistry reactions.
Why are you ignoring histidine?
Thank you, so much.
Is last proton transferred was the same that was trapped by His.??
Not necessarily, but possibly. At physiological pH, there are thousands of protons in a given cell that can be gained from solution hydronium ions. While it's possible that that one proton is the same, there are much higher odds that the transferred proton is simply lost to solution and a different one is regained. If you're trying to trace individual protons, for example by using deuterium labeling, you would end up with a rather low level of incorporation.
Thank you for the video, but the mechanism is not correct. please do some more research.