Action Potential | Graded Potentials

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  • Опубліковано 24 кві 2022
  • In this video, Dr Mike explains everything you need to know about how neurons send signals via action potentials!
    He also discusses different types of graded potentials including;
    - excitatory postsynaptic potentials (EPSPs)
    - inhibitory postsynaptic potentials (IPSPs)
    And what role neurotransmitters like glutamate and GABA play!
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    Twitter: @drmiketodorovic

КОМЕНТАРІ • 69

  • @marziarangel654
    @marziarangel654 2 роки тому +53

    You have no idea how much your videos helped me. I'm a slow learner and need repetition, and your methods make everything so clear. I can rewatch your videos and get confident in knowledge. I graduated my program with a 4.0 and I think largely thanks to having access to your videos. Thanks SO much.

  • @mikeb2644
    @mikeb2644 Рік тому +7

    I noticed that UA-cam is featuring this video. Normally I wouldn't care............
    .................BUT............"Action Potential" is probably Drs Matt and Mike's best video. Action potential is almost never explained clearly. I've watched many videos on it, and they're almost always bewildering.
    I was bewildered by action potential........until I watched this INCREDIBLE VIDEO. Made me a fan forever.

  • @wikkedJ12
    @wikkedJ12 Місяць тому +1

    your teaching style is unmatched - superb content!

  • @reirei6464
    @reirei6464 Рік тому +4

    I was so confsued about this concept, but holy crap this changed my whole view of electrical signaling subject, Thanks for the great video!!

  • @sommandal8597
    @sommandal8597 4 місяці тому +3

    After reading from my book i can't understand....but after watching your explanation finally i have a clear cut thoughts about this topic
    Thanks 😊
    Only the students like me fell how much worth your video😊😊😊

  • @alexcross3286
    @alexcross3286 4 дні тому

    This video saved my life and my grade. Action Potentials used to be my least favorite subject in intro psych and biology classes. could never keep up with all the components when it was being lectured for some reason. “Ligand gated this, voltage gated that, sodium, potassium, ATP, etc” it was overwhelming. I watched this video to help me prepare for a neuroscience exam tho and my mind was blown when I could finally understand the whole process. Not just that but realizing the WHY each part mattered. WHY the sodium-potassium pump is soooo important. That it resets the cell so action potentials can keep firing is amazing to me

  • @thelmangoma7070
    @thelmangoma7070 2 роки тому +2

    And just like that I feel confident to answer any question related to action potential.. Thank you ❤

  • @HasanAli-pm6jg
    @HasanAli-pm6jg 6 місяців тому +1

    Thanks you dr mike, from today I am one your students.
    I want to say, you are the best person to explain and teach someone like me.
    I understand very well.
    Thanks you please keep more🎉

  • @CharlesLacarin
    @CharlesLacarin 2 роки тому +6

    Another amazing video. Reviewing content for my paramedic exam and this helped so much !

  • @sophieekhegfejwgk
    @sophieekhegfejwgk 2 роки тому +5

    I have a test on the nervous system today, thanks for the very well-timed refresher video

  • @anaisrodriguez4420
    @anaisrodriguez4420 9 місяців тому +1

    The best explanation yet! Thank you so much for your videos!

  • @user-bb5cd4tr2i
    @user-bb5cd4tr2i 2 роки тому +14

    Honestly I just subscribed right after watching only 2 videos, this is real high quality content & this is really better than some paid contents available. Huge thanks for such great content Doc. U r doing great, keep it up. 👏👏👏

  • @user-di2im5tr3w
    @user-di2im5tr3w 3 місяці тому

    I was so confused by lecture notes and was sad, suddenly I noticed this video first and watched it. This video literally cleared my doubts and Big THANKS TO DR MIKE FOR MAKING OUR DAYS BETTER.

  • @akpoilihoghenekome8567
    @akpoilihoghenekome8567 Рік тому

    You've just gained a subscriber after watching 2videos.. thank you Dr matt. Your teachings are very helpful and easy to understand 🥰🥰

  • @RagingSymphony
    @RagingSymphony 2 роки тому +1

    Yet again high quality content. Thanks!

  • @belindaalderson7209
    @belindaalderson7209 Рік тому

    Thanks Dr Mike great to see an Aussie leading the way in this type of type of education - shame your not teaching at University of Newcastle, NSW but truly thanks for all your help it goes a long way. 🇦🇺

  • @braviousbundundoko278
    @braviousbundundoko278 Місяць тому

    Thank you so much Dr. Matt. This video helps a lot with my studies.

  • @mikeyslaps
    @mikeyslaps 2 роки тому +1

    yo Dr. Mike you lowkey saved my anat and phys grade so thanks for that but also you’re actually jacked please drop the routine

  • @raga5812
    @raga5812 2 роки тому +1

    Hii sir I'm from India 🇮🇳 and your lectures are really helping me a lot in my highschool studies 🙏🏻 thanks a lot

  • @Brandonwalsh18
    @Brandonwalsh18 2 місяці тому

    Crazy, you hit all the marks! Definitely got another subscriber just now!

  • @ishasoyza
    @ishasoyza Рік тому +2

    Please make a video for propagate of action potential and solitary conduction

  • @shyannakeesy8686
    @shyannakeesy8686 6 місяців тому

    Thank YOu! i have online anatomy and i had no idea how to figure this out. YOu explained it so clearly. thank you.

  • @YuvrajParmar-cl8lf
    @YuvrajParmar-cl8lf 5 місяців тому

    Appreciate your work sir❤ i was having so many doubts related to this topic but after this video my doubts are cleared . Thanks a lot sir❤

  • @Randomguy-ru7fn
    @Randomguy-ru7fn 2 роки тому +6

    Thank you so much. I had trouble understanding with some of my diagrams but this one made it really clear. Thank you for your efforts.

  • @kimberleyseon6412
    @kimberleyseon6412 4 місяці тому

    So well done. Thank you!

  • @lakshmidumpa
    @lakshmidumpa Рік тому

    Thank you so much for explaining well.

  • @jeromenimer1612
    @jeromenimer1612 Рік тому

    This is completely mind blowing. I love your videos😍

  • @Neuromorphin2
    @Neuromorphin2 19 днів тому

    Thank you Dr Mike ❤❤

  • @Random-wc4ob
    @Random-wc4ob Рік тому

    Brilliant explanation!

  • @jacobwn3965
    @jacobwn3965 Рік тому +4

    You are my fav Dr, you helped me so much and I hope you keep up the great work

  • @mmenadine9222
    @mmenadine9222 Рік тому

    Perfect explanation👍🥇

  • @ytzpro
    @ytzpro 5 місяців тому

    Great explanation. I wish I watched this before my final Anatomy exam loll I would have ended the class with an A!

  • @doctorsaoodwithacamera
    @doctorsaoodwithacamera 2 роки тому +1

    You're exceptional 👏

  • @Akselhtoo
    @Akselhtoo 2 роки тому +2

    I'M WAITING!!!😍😍😍

  • @kevinmontoya43
    @kevinmontoya43 17 днів тому

    This is amazing

  • @shellythalliburton7559
    @shellythalliburton7559 Рік тому

    Wow!!! Thanks Doc

  • @carlanderson6845
    @carlanderson6845 7 місяців тому

    Great video

  • @mmmlolo6722
    @mmmlolo6722 2 роки тому

    Best dr.♥️♥️

  • @stevejones3662
    @stevejones3662 23 дні тому

    Excellent work! Loved this lesson; brilliantly structured explanation. 1 question: Do positive sodium or potassium ions get attracted towards negative areas due to opposing charges or move away from each other by same change repulsion? Same outcome but subtely different reason? And I read somewhere that only small numbers of ions need to move to cause these charge changes?

  • @gabrielaelias6276
    @gabrielaelias6276 9 місяців тому +1

    great video !!

  • @chris-mj8792
    @chris-mj8792 Рік тому

    wow thank you so much !!!

  • @appiahrichard5921
    @appiahrichard5921 Рік тому +1

    I never understood this In class
    I'll stop attending lectures and watch you videos instead

  • @sadeemAbdullah1
    @sadeemAbdullah1 Рік тому

    🫡🫡🫡🫡🫡 اقوى استاذ اتحدااااك يالاستاذ البطل والله شرحك يجنن

  • @easymedicose
    @easymedicose 2 роки тому +1

    V r w8ing sir 🙌♥️

  • @amiraali818
    @amiraali818 2 роки тому

    Hey are you guys not doing podcasts anymore?

  • @laughedagain904
    @laughedagain904 2 роки тому

    Hello Dr.Mike..please do the special senses

  • @blairbeebebee8763
    @blairbeebebee8763 Рік тому

    Which Na channels have inactivation gate?

  • @jacquelineterrazas3343
    @jacquelineterrazas3343 Рік тому

    THANK YOUUU

  • @LTIMES-cw5tw
    @LTIMES-cw5tw Рік тому

    GOAT 🐐👍🏼

  • @Startpixie12
    @Startpixie12 10 днів тому

    Did you make a mistake when you said na/k pump restores hyper polarization back to resting membrane potential? That’s not possible because if anything, nak pump will make the inside more negative right.?… what actually restores hyper polarization back to resting membrane potential is the inward rectifier potassium leaky channels , nak pump will help to bring back the ionic concentration gradient.. please correct me if I’m wrong 😊

  • @baseleldeep5368
    @baseleldeep5368 5 місяців тому

    How much EPSP take ??
    And how mucjh AP take ???
    I heard from my leacturer that EPOS ×10 than AP

  • @julianfischer4207
    @julianfischer4207 Рік тому +1

    you may have just saved me from having to drop a and p and having to do a 6th year of undergrad

  • @billymeeks845
    @billymeeks845 Рік тому

    🙌🏼🙌🏼🙌🏼

  • @oldschoolwaverider
    @oldschoolwaverider Рік тому

    I thought they went across the synapse in a vesicle rather than diffused. That’s confused me a bit 😅 formative exam on Monday. Summative 16 days later

    • @noonereallyknows6643
      @noonereallyknows6643 Рік тому +2

      Vesicles containing the neurotransmitters actually fuse with the membrane of presynaptic neuron and "dump" the neurotransmitters outside into the synaptic cleft, and that's how they diffuse across, until they reach postsynaptic receptors. I know you are long finished with your exam but hopefully this response can help someone else. FYI ... vesicles can't leave the membrane which is why it's considered exocytosis - "exo" - outside, "cytosis" - cell

  • @sumaiyajhinuk8637
    @sumaiyajhinuk8637 2 роки тому

    1.for 3Na Out +2 k in-- causing negativity inside-ok.2.excitation - works on Na+ Ca channel. 3.inhibitory - acts on K channel.2.excitation and inhibition always work on in same time????.pl.sir. Give ans.

    • @rachell4576
      @rachell4576 2 роки тому

      I am not sure about any rare cases. However, based on the definition, if AP occur, it should be a depolarizing period before the AP can occur and it means the cell is being experienced EPSP. If it strong enough, the summation of these Graded potential (EPSP) such as the appearance of Glutamate then enough positive so become AP.
      Otherwise, if there is the appearance of GABA, the neutron is experienced IPSP, it means the cell becoming more negative and far away from threshold to be depolarizer so AP cannot occur.
      And AP characteristic is “all or non”, which means fired or not fired.
      You question about if EPSP AND IPSP can happens at same time or not, I believe the same time if EPSP and IPSP is during the summation of GRADED Potential, if 2 EPSP OCCUR WITH 2IPSP, then it will be canceled out and no AP occur!
      This is my opinion based on what I understand! If you have more idea about it, please correct me!

  • @MarcusWolford
    @MarcusWolford Рік тому

    Tall and Hard .. Thank You

  • @fuggully
    @fuggully 10 місяців тому

    stoppp😂 why the thumbnail HSHAJAJ

  • @peterjohn8625
    @peterjohn8625 2 роки тому

    Voltometer lol. Think you meant voltmeter.