How Does Aspirin Work?
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- Опубліковано 27 вер 2024
- How does aspirin target your pain? The plants that aspirin were derived from have been used as medicine for about 6000 years, we finally discovered how it works in 1971, and Lauren explains it to you now.
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3 minutes spent on the history of aspirin and what pain is, 10 seconds spent on explaining how it works.
Andyyyk47 right?! that's annoying :/ I wanted to know HOW as well
So aspirin binds to COX-2 enzymes so completely it doesn't unbend (ibuprofen and other NSAIDS do unbind) the prostaglandin cascade is very long but in short it increases lymphatic draining to the area, signals macrophages to enter the area, and also signals other cells to produce prostaglandins, out of curiosity if there was a channel that did this stuff in detail would you/anyone think it useful?
Thanks! Good looking out friend. You need a cape, hero.
i thought aspirin was anti coagulant and make blood flow better?
What about the blood thinning of aspirin?
I'd like to know about synthetic drugs and how they are made and how they compare.
Great vid btw!
what's the name of the classical piece at the beginning?
Thanks. I’m into pain but would like to get out of it. I have chronic widespread pain and there seems to be little relief. That’s no fun and causes many other problems. Doctors are no help, so I am trying to learn and experiment on my own. I appreciate any input I can get.
This post (and those I've been binging on) kick ass.
Next! YESSSS:)
Can you please do Advil or Tynelol. I would love it if you did. Ty and Great VIDEO!!
Advil is a brand name, and its consists of ibuprofen.
So to save the trouble: all NSAIDs work pretty much the same way as aspirin. The "mode of action" is almost the same. (Pharmacodynamics).The difference is in the pharmacokinetics: how the body deals with absorbing, distribution, metabolism, eliminating the Rx.
Please help i have tried everything from toxics & anything possible to get rid of the cats from doing poops in our parking and storage yard from viniger & lemon & rosemary. Ext..... they also do poops on all stares in the buildings .
It's about goddamn time you posted again
Allicin from garlic is supposed to be good to complement aspirin's blood clotting reducing properties. Cumin powder is supposed to have a lot of salicylic compounds too.
Does anyone know what the background music in this episode is called?
Which science website would you reccomend for doing research? Or which source would you say is the most credible on the internet? Great informative video by the way!!
*whatever you want to search* + UpToDate (database)
It also makes platelets less sticky, so they won't stick to an occlusion in the vessels during AMI or Angina.
Please can you do one on Salbutamol.
I'd like to see you make one on naproxen sodium
Can you please explain, how percocet/vicodin affects our brain, both short term and long term?
WHERE do I get her shirt
So clear! Thanks!
tell us abt tranquilizer
Talk about Novorapid (Insulin)
I love those bangs.
I mean I really love those bangs!
what about amphetamine salts?
Do a video explaining Desoxyn
how does panadol work on curing the headache
But what happens in the body when the aspirin wears off?? Does it disappear, get absorbed or does the cell reject the molecules??
And how does it work when talking about chronic pain, like with nerve pain, arthritis in hard to reach spots, like the sacroiliac joint....
I would love a video on nervepain specifically...
Sabina Hertzum aspirin irreversibly inhibits COX1&2. The enzyme is essentially removed as waste product with the drug in it. Your body then makes more COX. enzyme. Naproxen & Ibuprofen are reversible however and the body eliminates the drug but not the enzyme. COX enzymes have various functions including gastrointestinal protection so by taking too much of NSAIDs you can run into trouble.
Oh i know that - I have Crohn's disease and had my colon removed 15 years ago - was early diagnosed with Colitis and was operated for that, and after 6 healthy years I got sick again and that's when I found out I had Crohn's....
I haven't been able to use NSAID for 18 years - I get Methadone for my arthritis and nervepain...
I just asked because I've been interested in the process because of my own health ;)
Sabina Hertzum I'm sorry to hear that. Hope your MD&PharmD can work to help you
Leonid Denisenko - thank you - they do an ok job - by choice I'm not completely pain free but I make it work - my intent wasn't to seek sympathy - I really just wanted to explain where the question came from - but my health is not easily or shortly explained so I always end up telling a bunch....
But my health is also why I like these videos - there are loads of things I'd like to hear about, that is hard to get an explanation about that I can understand and retain because of my medication - videos just work great for me as an educational tool ;)
Totally understand where you're coming from. I'm a Pharmacy student & intern (not trying to show off lol). Of course I don't know your situation or what its like to be in your shoes, but try to always be compassionate. The info out there is often wrong or needlessly convoluted. If you have the time, speak to your pharmacist about the meds. they're usually more than happy to give you any info you'd like.
I want to know about seroquel.
I've wondered things like this since I was a kid
I am really interested scopolamine.
Cool shirt Lauren.
What funny timing as I've been dealing with a headache this morning and have never really understood how painkillers worked. Aspirin is one painkiller... does ibuprofen work in the same way? What about naproxen? And why can't you take them in the same time period?
Try it and if your alive comment us
goaskalice.columbia.edu/answered-questions/aspirin-vs-ibuprofen
Well that was too technical! but I still understood
how does albuterol work? i think its albuterol sulfate
How it damages mucous membrane of stomach and increase chances of blood loss????
Nice
How does ibuprofen help cure a headache
I was gonna ask that too lol
Kyle Medina I once downed 2000mg of ibuprofen with a dose of pre workout and I didn't die.
Kyle Medina It's much healthier than aspirin, actually.
and what should people do, if they have a headache
+Guitarocker493 Why would you do such a thing?
How about Morphine?
Yes, please
ya. do morphine.
I want to know where you bought your shirt so I can buy one lol
WRONG: it's not in the leaves, it's in the cork of the tree.
"and etcetera" triggered me
The "et" in et cetera literally means "and"
lol they are just dumb.
deetr nice pic bro
I like trolling grammar nerds. /Lauren
irregardless it's her perogative to use it.
Ibuprofen
same thing
Yes!
Mew For real
Tillidine :)
Mew its so much better
2:10 DAMN IT TAKE THE FIRE AWAY FROM THE FINGER DURING THE EXPLANATION, THAT POOR DRAWING IS IN PAIN!
Promethazine and codeine!
So why does asprin not work for all pain?
I face the pain like a man should.
eat*
Make a video comparing Aspirin and Paracetamol
usually the compound is derived from the bark not the leaves... and et cetera lol
Omg I wanna know where to get that shirt she's wearing
It's by Tara McPherson, available on Threadless! taramcpherson.threadless.com/ Their size charts are un-useful but their customer service is amazing, so ask them if you have any questions before you buy ^___^ /Lauren
How Does Tegretol Work?
thanks a lot :)
TCP
Hi
I only use ground willow that I gather myself. much better for you.
Very interesting. Although Aspirin isnt that strong.
Hydrocodone ( Vicodin ) or Amphetamines !
What's the deal with Adderall and Ritalin?
All this channel is Wikipedia read out
Lucas Williams yah but I don't mind ❤️❤️❤️
^___^ If you'd like to peruse my research sources, the links are in the Description above. /Lauren
Mic. dropped.
I've always heard it said no-si-septor. What is this naw-si-septor bs?
Can u snort aspirin??
how’d it go?
This video was very fking dopee. Youre a good talker cute Lady. Keep up the good wotk
Aspirin barely works for me. If I have alot of pain the only thing that works (although it doesnt work great or anything) is 2x 40mg of oxycodone
This is great, but play at .75 speed if you have a headache. She sort of bombards with information.
what is weed made out of?? pls make a video
weed? cannabis, is what.
jack sisneros THC, buddy. Tetrahydrocannabinol. Google that shit.
Tyler MacDonald it was a joke
Ah then you're good, man 👍
morphine
so what youre saying is... Pain is only mental, get up.
lithium orotate plssssssssssssssssssss
turn from your sins and believe in THE LORD JESUS CHRIST and be baptized in THE NAME of THE FATHER THE SON and THE HOLY SPIRIT( if you haven’t already before CHRIST comes back or before you die, so that you may be saved from the coming judgment…
She is gorgeous
is she hot? I'm not sure.
I got headache after listening to her lecture
1st?
How does Viagra work?
Asspryn
Adderall
Viagra lol
I couldn't stop staring at her shirt. Very cool but very distracting.
I'm attracted to this chick
Hail Hydra
Sub 10 view club
damnit. once again i'm barely going to learn anything because she is so pretty. 😜😁
seriously though; neat. now i know how that stuff i never take works. : ]
First
Omg this was boring Asf and i like to learn 😑
steroids
This lady is bad at reading the teleprompter discreetly lol sorry but very distracting
actually i produced synthetic ASA in a lab before. i know how it works.
didn't try it because it was only 98% pure.
Yolo
MegaMetinMetin the lab staff didn't allow it unfortunatly.
She looks like a Chinese Mannequin who has immortality
Aspirin is a non-selective COX inhibitor. It inhibits COX-1 (which does the same thing more or less) as well. This lack of selectivity isn't particularly relevant for inflammatory pain but is relevant for cardiovascular and stomach lining effects.
For the purposes of the video it might have been better to just say "COX" without specifying the type since selectivity (or lack thereof) doesn't really matter here.
how do i get high from asprin?
By vaping it!!! I'm serious... I do it all the time!!!
at 2:16 I was like take off your hands
Thank you for including the Sources!!! :D
Outstanding medical dictation. My assumption has always been Aspirin opens the blood vessels when you have a headache, given rich oxygenated blood back to the brain. I guess, I was wrong.
Maybe Adrenaline? That would be a neat vid.
how clarithromycin works
willow plant and salicin XD
very good channel very informative. Thanks for your videos and your hard work.
A highly-detailed one about birth control would be insightful. Many users don't understand how the different kinds actually work, and even which situations each should be used in, such as the difference in The Pill and various Morning After pills. For instance, there's a solo pill that's meant to prevent ovulation, but is commonly misunderstood as preventing implantation-- a pretty huge difference in usage!
You should do a pharmacology series!
Wait I took low dose aspirin for a headache, but I took 6, 81 mg pills. Is that too much? I feel sleepy.
AWESOME best ever channel!!!
Willow bark is a pain killer, not willow leaves.