"And we meet the Gorgeous hepatocyte, I almost completely forgot about the Macrophage for a minute" ... Dude. She has an axe that's bigger than she is. I don't think you want to trigger her jealousy. XD
Which begs the question. Who would win between the Cells at work macrophage and the Black macrophage? On the one hand the Cells at work macrophage has that huge axe and the 360 spin-to-win but the Black one has some serious crazy energy plus I spotted one in the intro with a scythe
@@nathanjensen7825 I like the idea that CAW Black Macrophage would come in full-crazy, while regular CAW Macrophage would bring the full-on Ara-Ara energy the whole time, pissing off CAW Black Macrophage("YOU'RE NOT TAKING THIS SERIOUSLY!!!") until she makes a stupid mistake.
The Hostess Club trip does sort of hint at the traditional benders that East Asian workers often end up being dragged into for 'corporate bonding' after work. Coming across the comatose form of a salaryman/office lady face down on the sidewalk or in a subway car sleeping off the effects of imbibing way too much alcohol after a futile attempt to keep pace with the boss is unfortunately common.
A double entendre in the Japanese that doesn't come across in the subs: When they're talking about detoxing, they use the word "nuku" which means to remove (as in remove the poison). But it also can mean, err in medical terms, to ejaculate.
Nuku (ぬく) is more like Japanese slang for masturbating (i.e. nukige, porn games), so "jerk off" would be a better translation. Ejaculation (射精) is a different term entirely.
Hi! As someone who actually lives in Japan but grew up in the west, I thought I'd provide some clarification regarding the likely reasons why they decided to depict the liver as a typical downtown nightlife district, why hepatocytes are depicted as a hostesses, and how strip clubs and host/hostess bars are different within Japanese culture. Apologies in advance for it being so long. I just thought it'd be interesting to share for people who don't know the context. I also thought it necessary to clarify what hosts/hostesses are so people don't generalize or apply their own culture to a very unique part of modern Japanese culture. If you're someone who is knowledgeable about Japan's work culture and work life, its quite clear that they are in the body of the stereotype of a salaryman working in, what is known as a "black company" (It's even referenced in the title of the series). Black companies take advantage of their workers by forcing them to work overtime without pay pretty much daily, by not giving them any benefits, emotionally and mentally abusing the staff, and overall doing shady, if not outright illegal, things in the workplace that threatens their workers. It's essentially a corporate version of being stuck in an abusive relationship. Part of the stereotype is that these people will, after working from morning until often past midnight, choose to destress by going straight to the downtown area, which is built around drinking. They're often 1 long stretch of different types of bars, and pachinko parlors, with the occasional strip club (but those are usually found in modern day versions of red light districts, which are often close to but separate from these downtown areas). So it makes sense that the liver of a black company worker is modeled after such an area considering that is most likely where he is imbibing the alcohol that the liver is detoxifying out of the blood. The other link is that the liver is an organ meant to detox the body and blood. So it makes sense that the hepatocytes are portrayed as hostesses, whose job is to help their customers destress/detox after an insanely grueling day of work. So it makes sense within the context of Japanese culture, corporate culture in particular, to have them portrayed as hostesses. It both provides context for not just what the cells' roles are, but for the person whose body they are a part of. It's also much more appealing, and easier to understand for a typical Japanese viewer than a waste treatment plant, which most people don't really have any understanding of either. I'll try to end this already long-winded comment as quick as I can, but I do think it's important to understand the differences between hostess clubs/bars and strip clubs within the context of Japanese culture, rather than viewing it through the lens of your own to properly pay respects to said culture. First, I want to make it clear that there is nothing innately wrong with either occupation, and people who judge hostesses and/or strippers need to get over themselves; people are often looked down on for having these types of jobs in and out of Japan, sadly. Now they are both jobs that are meant to allow customers to release stress. The major difference is in how they do it. Strippers (who also exist in Japan and are classified as different from hostesses here) do so by selling voyeurism and sexuality. Hostesses, on the other hand, do it by selling companionship. Their job is mainly to listen to the complaints and gripes of their customers, or just talk about random topics, while pouring them drinks and casually advertising more expensive alcohols. The main reason people go to them is because they are able to give people, who are very devoid of and in need of companionship, a sense of being needed and a sense of being taken care of at the same time; they can feel like they actually matter to someone for an allotted amount of time. Of course that isn't to say they don't dress to be sexy. the vast majority do, as to cater to the preferences of their target demographics. However, that is not their selling point, and they never take their clothes off. If you were to call a hostess a stripper for their clothing, then pretty much every woman in their twenties at a club, rave, or music festival would then be a stripper in your eyes. The Kupffer cell is obviously the exception. Her design clearly matches with western images of strippers, however there is also more Japanese context to consider here. I believe she is meant to be seen as a stripper, but even more than that a "dancer". I put "dancer" in quotes because in modern Japanese culture the belly dancer aesthetic is linked to fictional shamanistic religious rituals/ceremonies. You'll often see a "dancer" class in JRPGs or characters with similar aesthetics and roles in manga, anime, and light novels as well, and they are almost ALWAYS in Middle Eastern belly dancer garb. And considering how they depicted the Kupffer cell doing its job, I think its quite clear they were playing on that cultural perspective of the belly dancer aesthetic.
@@chrono-glitchwaterlily8776 its a similar concept but quite different. the pretending to be a family member is often more in a private setting, where the person goes to the client's home or they spend the day out. its much more free form, whereas hostesses and hosts can only be accessed within the clubs/bars they work at. The type of companionship is also slightly different since one is familial and the other is more like having a super flirty friend you go to vent to. The other is that hosts and hostesses are ultimately salesmen so they actively try to sell drinks by making sure your glass is full or suggesting other drinks. TLDR: Visiting hosts and hostesses is companionship that comes with an ego rub and alcohol, while hiring fake family is seeking out nostalgic familial bonds you cant get anymore. Also some people hire fake family for events like weddings or funerals to make it seem like they are doing better socially, than they are, or if they had falling outs with their real family and don't want the other guests to assume things or question why their family isn't there.
@@gaydonaldtrump Oh, thanks for letting me know. But, I'd be more embarrassed to be a grown person yet act like a schoolyard bully and try to shame someone for sharing their educated opinion. I'd also be more embarrassed about failing to realize the irony of suggesting its embarrassing to write about an anime in the comments section of what is essentially a 30 minute video essay on an anime, which I had just spent 30 minutes of my own time watching ... especially with my poorly translated weab username. But, honestly, thanks again. I had no idea this was something I should feel embarrassed over. I'll be sure to schedule "feel embarrassed" into my lunch break tomorrow. Cheers
"The mirror reflecting one's physical health" is a famous phrase for the Japanese. I remember this phrase began to be used for the 8020 campaign (keep 20 teethes until 80 age) by the Japan Medical Association in 2000. I relieved you agree with it XD.
lol, ok obv we all wanna skip over the part of the webpage that says "in some very rare cases it could be" before the "cancer" part. A REAL answer to this question: I have a ridge along the inside of my each cheek that indicates I jaw clench badly. The bad jaw clenching means I have TMJ. So the visual indicator in my mouth (ridges in my cheeks) gets identified by oral hygienists and they always ask if I'm doing treatment for TMJ. Also, of course, there's the erupted fluid filled sores that indicate HSV.... not that I'd know anything personally about that... nope... heard about it from a friend....
You know, it would be cool if Dr. Hope gets into cosplay a little, goes to a convention as Red Blood Cell, and meets a fellow cosplayer going as Macrophage. Thus, true romance is born.
@@bharatsn It depends - sometimes you need a specific colour, and trying to use the slider is way too much effort to try and match the colour you want.
"The immune system is not an intelligent system" I can attest to that since I had GBS (Guillain-Barre Syndrome over 2 years ago) and the after effects STILL linger in the form of weakened knee joints, primarily on my right side (I'm right- handed by the way) and my right hand trembles autonomously from time to time (making me felt like a chuunibyou). Plus, my high metabolic rate ironically causes me to be more prone to gastro-related ailments. Fun times... (monotone)
Thank you for clarifying the ADH thing. I was still wondering why they were drinking anti diuretic hormone and probably wouldn't have been able to sleep until figuring it out. Alcohol dehydrogenase....sometimes the solution is so simple.
@@fffernsw4dl539how poetic. But fir real though humans out here shoving poison inside their bodies with benefits that can literally be insignificant at average.
I think they picked that specific imagery since this is a body where things are breaking down and not being run properly. Those places have a very seedy image. Whereas a recycling centre has a very positive image and would have been more likely to have been used if the same place was shown on the previous show, if you follow me.
To be fair if they picked 'super dirty sewer and malfunctioning water recycling' it would still be applicably dark and depressing for this series, but ultimately, this series also mostly comedy and slice of life so they can't go too far in that direction.
My Liver being a 3rd Light District with beautiful Hepatocyte hostesses isn't a bad idea either, plus, there's a lot of places that are potentially can be designed as a recycling centre but what do I know?
The liver is the 2nd biggest organ in the body (1st being your skin) the host’s clubs could be just one part of it, and the other part could be the run down factory rust belt district.
The liver here is presented as some kind of "Red light district" in Japan where people went to detox and unwind in many ways, some of which unsavory and thus the sexual connotation. Also, protagonist was pressured to drink the same way young salarymen pressured to drink by their seniors.
As Cells at Work Black is as much a social commentary as it is a way to teach about the body, I really appreciate the representation of the service industry here. How you have to put up a smiling face constantly while you’re dealing with as much trouble as the people you’re serving are. It’s tough
I get such joy when he goes on tangents and says things like 'now in real life, these cells are much bigger' because it just tickles me to death that we're talking about that when they're tiny cell-people. Giggling like mad every time.
The liver is portrayed as a red light district basically, an adult-oriented street where people go to unwind after a long day of work. They typically contain the cities bars, gambling dens, and where the red blood cells go, a hostess club. A hostess club is basically a custom exclusive to Japan. They are popular with overstressed workers, so it makes sense that the red blood cells would go to a similar place. The women don't strip in them, it's basically paying for the company of a woman.
Judging by the episode titles and the feeling of the show, I'm thinking the person that these cells live in, is a man, who works in an office and is obsessed with climbing the corporate ladder.
From what I've seen in other shows though, that is unlikely to happen. And given this is a dark "medical" show, I'm worrying that this human is going to work themselves to death.
Definitely a male body. One of the episodes deals with erectile dysfunction. And definitely working way too hard with a sedentary lifestyle, since there's another episode about an embolism in the legs, so spending way too much time at a desk either trying to meet unreasonable quotas or trying to earn a promotion.
In the end of the intro and outro song you would actually see a human young man startled by the alarn clock .... This is most likely the body they are dealing with here ......
The first episode talks about the red cells being 90% hemoglobin and doing everything in their power to make the body work properly... *My body collapsing a lung to preserve energy during COVID infection and being severely anemic all my life* Hmm I must have not gotten that memo
PTSD Macrophage? that was my thought when I watched this episode last night. I also like the different way the medical terms are explained in Black, it doesn't pause, the explanations are sometimes given by characters.
I love how Black has themes and stuff. It's just like how the cells in Black work like in a black company to deal with their Body working in a black company; the cells are drug along by their boss to take a break and recoup from the alcohol with a nice mug of ADH, that their Body probably drank because he was drug along to a hostess club by their boss for heavy recreational drinking
Every time you upload your reaction to Cells at Work: Code Black I drop everything I’m doing to watch. Can’t wait to see your reaction to the rest of the series!
it's actually kinda makes sense why the liver depicted as a red light district, because liver is always the busiest part of the body and almost never rests
THIS MADE MY DAYYYY. What a nice surpriseeeee. Learning 'bout the cells with Dr Hope is one of my favourite things ever. PS: can i get some of your huge knowledge?
Pale mucosal membranes can be a sign of dehydration Bad breath can mean GI imbalance/upset Eroded teeth can mean a GERD or bulimia issue You can really tell a lot by looking in a person's (or animal's) mouth 😁
A 'strawberry tongue' (swollen red bumpy appearance) can indicate a Streptococcus pyogenes infection. White patches in the mouth can be oral thrush (Candida infection)
Absolutely One of the first times I went to my new dentist I got the question if I'd been sick recently. I was quite surprised by that cause 2 weeks prior to my visit I indeed had the flu. (Do note that was about 4-5 years ago aka before covid. Testing wasn't a thing yet)
You have a degree in computer science, then became a doctor? That's funny because that's the exact opposite of my life path! I was studying biomedical engineering to become a cancer genetics researcher, and then after taking an organic chemistry class, I switched out into computer science, got my degree in that, and have been a happy little coder ever since 😂
My dad passed away due to liver cirrhosis. The doctors first thought it was due to alcohol, hepatitis or smoking, which was not for his case at all. They later figured out it was due to certain medication he took when he was younger, said to help the body recover faster but we have no idea what actually are in them.
Thankfully I haven't gotten that before, just my gums being a bit more sensitive, I sometimes have to really work to get myself to brush my teeth because of depression, though I try to make up a bit by also using hydrogen peroxide to help my gums and teeth stay a bit more clean, helps with whitening since I also drink a lot of coffee
I can't imagine what you will be saying in the next Black episode, Doc. I think youtube might get squeamish about what is coming!! Anyway, always entertaining and thank you for all the hard work you do.
/So.. to Opsinise is basically is the Cellular equivalent of dousing something with condiments (Tomato Ketchup, Brown Sauce, Mayo, Mustard, etc) i guess?
In response to your lil quiz, if the mouth and gums has a bluish tint, called cyanosis, it's indicative of lack of O2 in the body's hemoglobin. I just learned that last week in anatomy!
As for cirrhosis (17:41) we don't see a depiction of it just yet but an early sign of it is represented with one of the hepatocytes not feeling too well.
this man literally went through half of my immunology notes for me in one episode I am thankful I totally forgot about opsonisation. If only he'd start talking about co-receptors
I think they could have shown fibrosis by giving the liver cells scars and/or skin graft marks.since they showed how they looked when they were healthy on the first ep, it would have been a cool way to visually show damage
I remember when I was sick; As the medicine they prescribed was very strong, it could damage my liver, so the specialist always sent me to liver analysis to see if it was in good condition. I'm reading the manga and when I get to this chapter I remember this; poor my liver that endured tremendous medication.
Speaking of changes from the manga, they took out White looking jealous after seeing Red with the hepatocyte. Which is weird, considering the anime added a scene earlier this same episode where her friends suggest he's into her, after which point it would make more sense for her to react like that.
Yeah I jumped so fast too. I left a conversation mid way just because of my notification for this 🤣 Don’t worry! I apologized and explained. My friends are aware how much I enjoy this channel.
5:20 - I could imagine both stress and sleep deprivation being associated with dry mouth (especially if the deprivation is through sleep apnoea), and a dry mouth tends to be a good environment for all manner of nasties. That said I'm not a doctor nor a dentist, but I did do my research degree in a dental school.
It’s a little more complicated, but the main cause of my father’s death was cirrhosis of the liver. Further Explanations: He was on a lot of medications for it, but we were not told by the liver specialist that the medication could also affect the kidneys, resulting in a build-up of ammonia, which effected his brain, and this combination ultimately killed him. I still think my mother should have sued that doctor for negligence but I think she just wanted to put the whole mess behind her and not dwell on it.
Alcohol is used to help people not loose fingers when they are rescued from the snow. The body is keeping the blood to the main organs but the alcohol makes it flow again to the fingers and everywhere.
The liver is designed after an actually existing entertainment/red light district in Tokyo: Kabukichō If you look it up on Wikipedia you'll see why - the entrance looks exactly the same :)
I remember getting a lot of canker sores last summer. Just started a new job so I guess it could be stress. A coworker recommended zinc tablets. I started taking one a day when I had the sores and they vanished pretty quickly.
In one of my med lab tech classes, the teachers took some fresh blood and added some bacteria to it. After a few minutes, we were able to look at them under the scope. I had found one white blood cell that had four endosomes in the phagocytosis.
Me: What is look like inside of my body? My body: "In the grim darkness of the far future, there is only war" **Exterminatus on Covid** Me: Oh... right
You do such a good job with these, and I know you’re overwhelmed, but I do hope you’ll keep going with the main series. Cells at Work Black is so dark that I’m even avoiding the reviews.
I learn so much each time I watch one of your videos. Very entertaining and educational! Special shoutout to the commenters who post clarifications on translation: very helpful to my studies in the Japanese language :)
Cirrhosis aka bad enough to irreparably damage the only organ that can literally completely regenerate from only a fraction of itself. Addiction's a hell of a thing.
18:20 This thing you just said legit made me realize that *hepat* _itis_ is related to *hepat* _ocytes_ , AKA the liver. I hadn't made that connection at all, I hadn't even thought about hepatitis since I got involved with Cells at Work!. Thanks!
Well, they needs some sustances to get rid of alcohol. The fun thing is that when you drink and feel good, your body has a bad time, and when your cells drink to get rid of alcohol they make you suffer the pain.
12:30 I didn't notice that the background is actually a painting until I see the green screen. As far as paintings go, that's quite a good recreation of your studio!
Honestly I just enjoy any cell that has three nucleuses and internal organs that can completely regenerate (my pops worked in regenerative bio for a while so I just picked up fun stuff like this lol)
The liver is based on a place in Japan, called Kabukicho (more known as Kamurocho because of the Yakuza series) where there's a lot of host/hostess clubs and pubs. Basically a giant red light district. EDIT: According to Wikipedia it is Kabukicho.
My dad has Hemochromatosis and Non-alcoholic Cirrhosis of the Liver, he was born with it and recently it's been getting worse. But just last month he was able to have his first TIPS surgery, and is starting on the path of getting it handled finally. I wish the show touched a bit more on the liver and different types of illnesses it can have to help show how important of an organ it is. Besides that though, I love this series! Normally after school I watch your reactions to the show, it helped me a lot during my Biology class with the way you explain what the words mean and for what they stand for, so thank you for creating these reaction videos ^^
Part of Japanese corporate culture are after-work drinking parties called _nomikai_ as well as less formal outings with one's boss or other co-workers. It's both a way of blowing off steam and team-building via "nominication," a portmanteau of _nomu_ (drinking) and "communication." Normally you would go to a bar, restaurant, or _izakaya_ (basically a Japanese pub). But if this body is the Black company and the Red Blood Cells are the salarymen, it's not so surprising their cringe-y supervisor chose to take them somewhere more uhhh *risqué* like a hostess club. Also FYI there are host clubs in Japan where good-looking men tend to their clients, so I imagine that's where the Macrophages and Neutrophils hang out after a hard day of phagocytosing pathogens.
So something I think that's worth mentioning. The use of the word "pissed" in British and American English actually isn't consistent. In the UK it means drunk, in the US it means angry. I assume that some cross usage happens in both countries but that's the primary usage. Here in Australia I think it gets used both ways fairly regularly.
Glossitis (iron deficiency), central cyanosis(heart failure), and thrush (immunosuppression) can be seen on the mouth/tongue. Cranial nerve examination can be done by getting them to stick their tongue out, tongue strength, gag reflex, and palatoglossal arch levels for the bottom cranial nerves for any stroke/bleeding in the lower brainstem/PICA/any blood supply obstruction
This universe has a very interesting implication, not including bacteria and viruses that invade the body as well as accidents, whoever is in charge of the brain is responsible for a number of problems that the cells and the world (Body) go through. Such as smoking, drinking, and risky things that result in injury. This would likely never happen, but a few cells need to go over to the ones controlling the brain and knock some sense into them.
I would have liked to hear a comment on the bit at the end where the body drinks more alcohol. I don't remember exactly what it was called (I think it included the word "tiger"), but it apparently is the idea that taking a small amount of what is making you feel bad will help you recover faster. The anime actually says that there is no scientific basis for it, but I heard from someone that it is actually known to work for some reason. I'm curious what someone more proficient in medicine thinks of this.
"I almost forgot about macrophage there." 😂 Dedication lmao
I immediately thought "he's cheating on his waifu" 🤣
He's 100% weeb now
We can have more than one waifu...
NEW WAIFU ALERT!
He's reaching stage 2 of weeb, cheating on waifu!
"I've been reading the Manga"
Congratulations Internet, you've turned a doctor into an Anime/Manga junkie. Lol
ONE OF US! ONE OF US!
@@RafaelMonteiroMaia ONE OF US! ONE OF US! ONE OF US!
WE GOT HIM!!!!
**whispers**
_There are other Doctors that are pulled in via Cells at Work_
Oh hi guys
@@erika002 ONE OF US, ONE OF US!
It's not a strip club, is a "host" club women acompany you for drinking but you cannot touch or do anything indecent or you would be expelled.
That's just what we call it in the UK; you can't touch or do anything indecent in a strip club.... so I'm told
@@DrHopeSickNotes HMMMM
@@DrHopeSickNotes The hostess clubs don’t actually involve any stripping, that’s the difference
@@weeb69 nice pp
@@UltimatePower01 that's why I think it's strip bar, as they are pretty naked in the manga :)
"And we meet the Gorgeous hepatocyte, I almost completely forgot about the Macrophage for a minute"
... Dude. She has an axe that's bigger than she is. I don't think you want to trigger her jealousy. XD
Which begs the question. Who would win between the Cells at work macrophage and the Black macrophage?
On the one hand the Cells at work macrophage has that huge axe and the 360 spin-to-win but the Black one has some serious crazy energy plus I spotted one in the intro with a scythe
@@nathanjensen7825 I like the idea that CAW Black Macrophage would come in full-crazy, while regular CAW Macrophage would bring the full-on Ara-Ara energy the whole time, pissing off CAW Black Macrophage("YOU'RE NOT TAKING THIS SERIOUSLY!!!") until she makes a stupid mistake.
I too love Macrophage's enormous.... axe.
@@FourthDerivative yes,,,axe 💃✨
Weeeeellll it’s a couple nanometers long
The Hostess Club trip does sort of hint at the traditional benders that East Asian workers often end up being dragged into for 'corporate bonding' after work. Coming across the comatose form of a salaryman/office lady face down on the sidewalk or in a subway car sleeping off the effects of imbibing way too much alcohol after a futile attempt to keep pace with the boss is unfortunately common.
Thank God that alcohol is looked down upon in our culture. Forcing someone to drink is like a terrible thing to commit here.
@@subratanandy2142what country?
@@beashemmad.sayson545India
A double entendre in the Japanese that doesn't come across in the subs: When they're talking about detoxing, they use the word "nuku" which means to remove (as in remove the poison). But it also can mean, err in medical terms, to ejaculate.
they could have replaced it with needing a "release" for their tensions.
Should be pinned as the actual explanation
there's also "shasei" 射精 (the more vulgar version)
p.s. I don't know how to read japanese but I had to confirm this via google (not translate)
Nuku (ぬく) is more like Japanese slang for masturbating (i.e. nukige, porn games), so "jerk off" would be a better translation. Ejaculation (射精) is a different term entirely.
@@ballboys607 hmm yeah that's what I thought as well, the op said "ejaculate' so my mind went there. Eh fair enough.
Ed: "Macrophages eat pathogens"
Me: "So a sword is a utensil?"
A sword is just a really big knife. So yes.
The only difference between a sword and a knife is the handle.
@@MsLilly200 too bad there aren’t pitchforks. That would be a bit too on the nose, I guess?
@@JackieOwl94 well eosinophils are phagocytes and have pitchforks so thechnically
@@meldavid4407
I always though that "sword" represent toxins that are killing the pathogens...and unfortunely the tissues :(
Respect dr. Hope, even though he is busy dealing with Covid, he doesn't forget to catch up to this series... Love ya doc
Hi! As someone who actually lives in Japan but grew up in the west, I thought I'd provide some clarification regarding the likely reasons why they decided to depict the liver as a typical downtown nightlife district, why hepatocytes are depicted as a hostesses, and how strip clubs and host/hostess bars are different within Japanese culture. Apologies in advance for it being so long. I just thought it'd be interesting to share for people who don't know the context. I also thought it necessary to clarify what hosts/hostesses are so people don't generalize or apply their own culture to a very unique part of modern Japanese culture.
If you're someone who is knowledgeable about Japan's work culture and work life, its quite clear that they are in the body of the stereotype of a salaryman working in, what is known as a "black company" (It's even referenced in the title of the series). Black companies take advantage of their workers by forcing them to work overtime without pay pretty much daily, by not giving them any benefits, emotionally and mentally abusing the staff, and overall doing shady, if not outright illegal, things in the workplace that threatens their workers. It's essentially a corporate version of being stuck in an abusive relationship. Part of the stereotype is that these people will, after working from morning until often past midnight, choose to destress by going straight to the downtown area, which is built around drinking. They're often 1 long stretch of different types of bars, and pachinko parlors, with the occasional strip club (but those are usually found in modern day versions of red light districts, which are often close to but separate from these downtown areas). So it makes sense that the liver of a black company worker is modeled after such an area considering that is most likely where he is imbibing the alcohol that the liver is detoxifying out of the blood.
The other link is that the liver is an organ meant to detox the body and blood. So it makes sense that the hepatocytes are portrayed as hostesses, whose job is to help their customers destress/detox after an insanely grueling day of work. So it makes sense within the context of Japanese culture, corporate culture in particular, to have them portrayed as hostesses. It both provides context for not just what the cells' roles are, but for the person whose body they are a part of. It's also much more appealing, and easier to understand for a typical Japanese viewer than a waste treatment plant, which most people don't really have any understanding of either.
I'll try to end this already long-winded comment as quick as I can, but I do think it's important to understand the differences between hostess clubs/bars and strip clubs within the context of Japanese culture, rather than viewing it through the lens of your own to properly pay respects to said culture. First, I want to make it clear that there is nothing innately wrong with either occupation, and people who judge hostesses and/or strippers need to get over themselves; people are often looked down on for having these types of jobs in and out of Japan, sadly. Now they are both jobs that are meant to allow customers to release stress. The major difference is in how they do it. Strippers (who also exist in Japan and are classified as different from hostesses here) do so by selling voyeurism and sexuality. Hostesses, on the other hand, do it by selling companionship. Their job is mainly to listen to the complaints and gripes of their customers, or just talk about random topics, while pouring them drinks and casually advertising more expensive alcohols. The main reason people go to them is because they are able to give people, who are very devoid of and in need of companionship, a sense of being needed and a sense of being taken care of at the same time; they can feel like they actually matter to someone for an allotted amount of time.
Of course that isn't to say they don't dress to be sexy. the vast majority do, as to cater to the preferences of their target demographics. However, that is not their selling point, and they never take their clothes off. If you were to call a hostess a stripper for their clothing, then pretty much every woman in their twenties at a club, rave, or music festival would then be a stripper in your eyes.
The Kupffer cell is obviously the exception. Her design clearly matches with western images of strippers, however there is also more Japanese context to consider here. I believe she is meant to be seen as a stripper, but even more than that a "dancer". I put "dancer" in quotes because in modern Japanese culture the belly dancer aesthetic is linked to fictional shamanistic religious rituals/ceremonies. You'll often see a "dancer" class in JRPGs or characters with similar aesthetics and roles in manga, anime, and light novels as well, and they are almost ALWAYS in Middle Eastern belly dancer garb. And considering how they depicted the Kupffer cell doing its job, I think its quite clear they were playing on that cultural perspective of the belly dancer aesthetic.
I hope the good doctor sees this because this is a great explanation of the cultural context!
Thank you. Quick question though, when you say people sell companionship, is it the same as people buying someone to be their sister or mother
@@chrono-glitchwaterlily8776 its a similar concept but quite different. the pretending to be a family member is often more in a private setting, where the person goes to the client's home or they spend the day out. its much more free form, whereas hostesses and hosts can only be accessed within the clubs/bars they work at. The type of companionship is also slightly different since one is familial and the other is more like having a super flirty friend you go to vent to. The other is that hosts and hostesses are ultimately salesmen so they actively try to sell drinks by making sure your glass is full or suggesting other drinks.
TLDR: Visiting hosts and hostesses is companionship that comes with an ego rub and alcohol, while hiring fake family is seeking out nostalgic familial bonds you cant get anymore.
Also some people hire fake family for events like weddings or funerals to make it seem like they are doing better socially, than they are, or if they had falling outs with their real family and don't want the other guests to assume things or question why their family isn't there.
@@gaydonaldtrump it's more of a cultural teaching than an anime rant so no need to be embarrassing
@@gaydonaldtrump Oh, thanks for letting me know. But, I'd be more embarrassed to be a grown person yet act like a schoolyard bully and try to shame someone for sharing their educated opinion. I'd also be more embarrassed about failing to realize the irony of suggesting its embarrassing to write about an anime in the comments section of what is essentially a 30 minute video essay on an anime, which I had just spent 30 minutes of my own time watching ... especially with my poorly translated weab username.
But, honestly, thanks again. I had no idea this was something I should feel embarrassed over. I'll be sure to schedule "feel embarrassed" into my lunch break tomorrow. Cheers
"The mirror reflecting one's physical health" is a famous phrase for the Japanese.
I remember this phrase began to be used for the 8020 campaign (keep 20 teethes until 80 age) by the Japan Medical Association in 2000.
I relieved you agree with it XD.
Quiz answer:
Symptom: Sore in mouth
Internet's answer: you're dying
According to Internet I have 3 types of cancer already xd
Symptom: Hangover
Internet's Answer: You have cirrhosis.
lol, ok obv we all wanna skip over the part of the webpage that says "in some very rare cases it could be" before the "cancer" part.
A REAL answer to this question: I have a ridge along the inside of my each cheek that indicates I jaw clench badly. The bad jaw clenching means I have TMJ. So the visual indicator in my mouth (ridges in my cheeks) gets identified by oral hygienists and they always ask if I'm doing treatment for TMJ.
Also, of course, there's the erupted fluid filled sores that indicate HSV.... not that I'd know anything personally about that... nope... heard about it from a friend....
I am living for the continuing saga of Dr Hope x Macrophage!!
@Digicraftmon the Crystal Gem Oh no...
You know, it would be cool if Dr. Hope gets into cosplay a little, goes to a convention as Red Blood Cell, and meets a fellow cosplayer going as Macrophage. Thus, true romance is born.
Dude don’t even worry. I ALSO have a degree in CS and missed the hex reference 😆
I'm more suprised a doctor also took a CS degree. Daheck
Don't feel too bad. The only reason I recognized it as hex code was because I'm familiar with its usage due to a certain video game franchise...
Hah same! I'm currently doing my degree in Industrial Design, and I missed that too! 😄
to be honest who puts hex number to select color, just use the slider
@@bharatsn It depends - sometimes you need a specific colour, and trying to use the slider is way too much effort to try and match the colour you want.
Why are mouth ulcers on fire?
Because they are....
In-flamed
:V
That was punny. :3
Nice one!!
"The immune system is not an intelligent system"
I can attest to that since I had GBS (Guillain-Barre Syndrome over 2 years ago) and the after effects STILL linger in the form of weakened knee joints, primarily on my right side (I'm right- handed by the way) and my right hand trembles autonomously from time to time (making me felt like a chuunibyou).
Plus, my high metabolic rate ironically causes me to be more prone to gastro-related ailments. Fun times... (monotone)
Thank you for clarifying the ADH thing. I was still wondering why they were drinking anti diuretic hormone and probably wouldn't have been able to sleep until figuring it out. Alcohol dehydrogenase....sometimes the solution is so simple.
I really like the idea of drinking to get rid of alcohol.
So... drinkable breathalyzer, anyone?
uno reverse card
Its also pretty sad, the fact that you're putting your body in harm forces the cells to also commit the same deed as you just so they can counteract.
@@fffernsw4dl539how poetic. But fir real though humans out here shoving poison inside their bodies with benefits that can literally be insignificant at average.
I think they picked that specific imagery since this is a body where things are breaking down and not being run properly. Those places have a very seedy image. Whereas a recycling centre has a very positive image and would have been more likely to have been used if the same place was shown on the previous show, if you follow me.
To be fair if they picked 'super dirty sewer and malfunctioning water recycling' it would still be applicably dark and depressing for this series, but ultimately, this series also mostly comedy and slice of life so they can't go too far in that direction.
Indeed.
Why not both but the recycling center is a rundown malfunctional place
My Liver being a 3rd Light District with beautiful Hepatocyte hostesses isn't a bad idea either, plus, there's a lot of places that are potentially can be designed as a recycling centre but what do I know?
The liver is the 2nd biggest organ in the body (1st being your skin) the host’s clubs could be just one part of it, and the other part could be the run down factory rust belt district.
So... when will you be cosplaying the Code Black Red Blood Cell protagonist? :)
You have to go back a ways, but Dr. Hope did cosplay/act in a fan-made live action Cells at Work video as the Helper T Cell!
I hadn't seen that! Helper T is pretty cool too :)
@@Rikativity I would really appreciate it if you can send us the link here please~ Thank you so much ^^
@@arfarfsarahmeow Found it!
ua-cam.com/video/oy0VRtsg0ck/v-deo.html
He's at 30 sec and clearer at 1min 10sec. ^_^
Much love to our favorite nerdy Doc!
@@Rikativity eh, really? do u have the link?
A sign in the mouth.
I guess awful breath (or halitosis) and it would represent tooth decay or maybe infection.
The liver here is presented as some kind of "Red light district" in Japan where people went to detox and unwind in many ways, some of which unsavory and thus the sexual connotation. Also, protagonist was pressured to drink the same way young salarymen pressured to drink by their seniors.
The Liver sign is also designed after Kabukicho's iconic sign, so its pretty much based off Kabukicho in general
As Cells at Work Black is as much a social commentary as it is a way to teach about the body, I really appreciate the representation of the service industry here.
How you have to put up a smiling face constantly while you’re dealing with as much trouble as the people you’re serving are. It’s tough
I get such joy when he goes on tangents and says things like 'now in real life, these cells are much bigger' because it just tickles me to death that we're talking about that when they're tiny cell-people. Giggling like mad every time.
The liver is portrayed as a red light district basically, an adult-oriented street where people go to unwind after a long day of work. They typically contain the cities bars, gambling dens, and where the red blood cells go, a hostess club. A hostess club is basically a custom exclusive to Japan. They are popular with overstressed workers, so it makes sense that the red blood cells would go to a similar place. The women don't strip in them, it's basically paying for the company of a woman.
Judging by the episode titles and the feeling of the show, I'm thinking the person that these cells live in, is a man, who works in an office and is obsessed with climbing the corporate ladder.
From what I've seen in other shows though, that is unlikely to happen. And given this is a dark "medical" show, I'm worrying that this human is going to work themselves to death.
Guessing he works for a black company, shit rolls downhill, so his body is a black company working his cells to death.
Definitely a male body. One of the episodes deals with erectile dysfunction. And definitely working way too hard with a sedentary lifestyle, since there's another episode about an embolism in the legs, so spending way too much time at a desk either trying to meet unreasonable quotas or trying to earn a promotion.
In the end of the intro and outro song you would actually see a human young man startled by the alarn clock ....
This is most likely the body they are dealing with here ......
Don't forget that he also has terrible stress coping mechanisms, seeing as he's not only a smoker and an alcoholic, but he almost gave himself an sti.
"stress and sleep deprivasion can have wide spread health problems"
*Me at 2am during exams week watching this video*: well damn
The first episode talks about the red cells being 90% hemoglobin and doing everything in their power to make the body work properly...
*My body collapsing a lung to preserve energy during COVID infection and being severely anemic all my life*
Hmm I must have not gotten that memo
PTSD Macrophage? that was my thought when I watched this episode last night. I also like the different way the medical terms are explained in Black, it doesn't pause, the explanations are sometimes given by characters.
I love how Black has themes and stuff.
It's just like how the cells in Black work like in a black company to deal with their Body working in a black company; the cells are drug along by their boss to take a break and recoup from the alcohol with a nice mug of ADH, that their Body probably drank because he was drug along to a hostess club by their boss for heavy recreational drinking
"Red Blood Cell, totally busted!"
Kettle and pots, doc, kettle and pots
Hahaha 😂
Fact.
Every time you upload your reaction to Cells at Work: Code Black I drop everything I’m doing to watch. Can’t wait to see your reaction to the rest of the series!
13:56 the face of a man who has found a new Waifu.
dont say that, macrophage is the supreme waifu
Dr. Hope going to making an harem by the end of this. Can't wait. Lol
@@t.thomas8919 nooooOOOOOOOOOOOOOOOooooo
He likes all 3!
it's actually kinda makes sense why the liver depicted as a red light district, because liver is always the busiest part of the body and almost never rests
"I almost forgot about the macrophage there" very harsh statement, Dr.
THIS MADE MY DAYYYY. What a nice surpriseeeee. Learning 'bout the cells with Dr Hope is one of my favourite things ever. PS: can i get some of your huge knowledge?
That sounds so much like a double entendre I can't even.
Pale mucosal membranes can be a sign of dehydration
Bad breath can mean GI imbalance/upset
Eroded teeth can mean a GERD or bulimia issue
You can really tell a lot by looking in a person's (or animal's) mouth 😁
A 'strawberry tongue' (swollen red bumpy appearance) can indicate a Streptococcus pyogenes infection.
White patches in the mouth can be oral thrush (Candida infection)
Koplick and measles
What’s a GI imbalance
Absolutely
One of the first times I went to my new dentist I got the question if I'd been sick recently. I was quite surprised by that cause 2 weeks prior to my visit I indeed had the flu.
(Do note that was about 4-5 years ago aka before covid. Testing wasn't a thing yet)
hence the saying straight from the horse's mouth.
I can't believe this show actually got me emotional .....
Yeah
Ik especially the episode were his friend dies in the stomach almost cried at that one 😪😢
Made me think how humans easily destroy our inside, rough honestly.
You have a degree in computer science, then became a doctor? That's funny because that's the exact opposite of my life path! I was studying biomedical engineering to become a cancer genetics researcher, and then after taking an organic chemistry class, I switched out into computer science, got my degree in that, and have been a happy little coder ever since 😂
My dad passed away due to liver cirrhosis. The doctors first thought it was due to alcohol, hepatitis or smoking, which was not for his case at all. They later figured out it was due to certain medication he took when he was younger, said to help the body recover faster but we have no idea what actually are in them.
I've gotten canker sores on my gums before because I wasn't brushing my teeth due to stress. Basically it was like a hole in my gums.
Thankfully I haven't gotten that before, just my gums being a bit more sensitive, I sometimes have to really work to get myself to brush my teeth because of depression, though I try to make up a bit by also using hydrogen peroxide to help my gums and teeth stay a bit more clean, helps with whitening since I also drink a lot of coffee
2:03 i love the fact you Insert this clip again 😆
Never been this early, still watching. Keep the faith, stay strong doc! =D
I can't imagine what you will be saying in the next Black episode, Doc. I think youtube might get squeamish about what is coming!! Anyway, always entertaining and thank you for all the hard work you do.
Hi fellow Azure
Be strange for the next episode after that though considering it involves an STD.
Erectile dysfunction episode?
/So.. to Opsinise is basically is the Cellular equivalent of dousing something with condiments (Tomato Ketchup, Brown Sauce, Mayo, Mustard, etc) i guess?
In response to your lil quiz, if the mouth and gums has a bluish tint, called cyanosis, it's indicative of lack of O2 in the body's hemoglobin. I just learned that last week in anatomy!
Just finished the first volume of that manga! This scene was just way too funny...
As for cirrhosis (17:41) we don't see a depiction of it just yet but an early sign of it is represented with one of the hepatocytes not feeling too well.
this man literally went through half of my immunology notes for me in one episode I am thankful
I totally forgot about opsonisation.
If only he'd start talking about co-receptors
The first Cells at Work taught me a lot about my body
This made me think about on what am I doing to my body
10:21 not gonna lie... The liver has a dope theme song 💿🎧
Love to know the whole playlist. Got to be epic. Lol
Its the same composer that did the JJBA soundtrack! Yugo Kanno!!
Loving the clean shaven, fresher look, Dr. Much better. Really enjoying this series, thank you for taking the time.
I think they could have shown fibrosis by giving the liver cells scars and/or skin graft marks.since they showed how they looked when they were healthy on the first ep, it would have been a cool way to visually show damage
I remember when I was sick; As the medicine they prescribed was very strong, it could damage my liver, so the specialist always sent me to liver analysis to see if it was in good condition.
I'm reading the manga and when I get to this chapter I remember this; poor my liver that endured tremendous medication.
Speaking of changes from the manga, they took out White looking jealous after seeing Red with the hepatocyte. Which is weird, considering the anime added a scene earlier this same episode where her friends suggest he's into her, after which point it would make more sense for her to react like that.
The way I jumped on this.
Yeah I jumped so fast too. I left a conversation mid way just because of my notification for this 🤣 Don’t worry! I apologized and explained. My friends are aware how much I enjoy this channel.
same lol!
5:20 - I could imagine both stress and sleep deprivation being associated with dry mouth (especially if the deprivation is through sleep apnoea), and a dry mouth tends to be a good environment for all manner of nasties. That said I'm not a doctor nor a dentist, but I did do my research degree in a dental school.
-Waste disposal
-Chemical management
-Strip Club
All the same really
Dr. Hope sees a body burning "coooool" 😅
"White blood cells are 10x bigger than pathogens"
My mind: **paints a picture where white blood cells is like godzilla**
Well their boobs in this series are MUCH bigger that's for sure... O_O
@@veng3r663 wtffffffff
Good on ya for sticking close to the one true love in Cells at Work
Hepatocyte is temporary, Macrophage is forever!
It’s a little more complicated, but the main cause of my father’s death was cirrhosis of the liver.
Further Explanations: He was on a lot of medications for it, but we were not told by the liver specialist that the medication could also affect the kidneys, resulting in a build-up of ammonia, which effected his brain, and this combination ultimately killed him.
I still think my mother should have sued that doctor for negligence but I think she just wanted to put the whole mess behind her and not dwell on it.
He is the only UA-camr who says NOT to turn on Notifications
Its a strip club to fit the theme of the body it inhabits, no? Im sure in the original series it would be a recycling plant
I know, right?
Or a large restaurant district that serves food and drink that rids the redbloodcells of harmful materials
And the midneys wud be hot springs
Hostess clubs are not strip clubs.
Seeing a White blood cell ripping off the limbs of small dog sized pathogen monsters and eating them alive would be equally horrible.
My doctor once told me that my high stress and anxiety puts me at risk for ulcers. THIS DID NOT HELP ME REDUCE MY STRESS AND ANXIETY!!!
Alcohol is used to help people not loose fingers when they are rescued from the snow. The body is keeping the blood to the main organs but the alcohol makes it flow again to the fingers and everywhere.
The liver is designed after an actually existing entertainment/red light district in Tokyo: Kabukichō
If you look it up on Wikipedia you'll see why - the entrance looks exactly the same :)
I remember getting a lot of canker sores last summer. Just started a new job so I guess it could be stress. A coworker recommended zinc tablets. I started taking one a day when I had the sores and they vanished pretty quickly.
I would love he continued with the complete season of this anime. It’s really funny hear his knowledge and his reactions time to time.
My first experience with the word "cirrhosis" was when my pet turkey in Rimworld got into my beer stock.
13:11 Shamelessly pausing at the thigh shot. A true man of culture
Great timing! Lol
In one of my med lab tech classes, the teachers took some fresh blood and added some bacteria to it. After a few minutes, we were able to look at them under the scope. I had found one white blood cell that had four endosomes in the phagocytosis.
You have no idea how long I've been waiting for you to cover this 🙏🏼
Hands down the best channel to review Cells at Work👍👍👍👍😊
Me: What is look like inside of my body?
My body: "In the grim darkness of the far future, there is only war" **Exterminatus on Covid**
Me: Oh... right
Ah i see a fan of the imperium
If my body was represented in warhammer 40k it would the the plague wars
I see you are a man of culture as well...
@@Tydorstus *_「Purple Smoke」_* ?
I'm currently A-okay, so mine is probably Holy Terra or Mcragge.
待ってました！！😀
いつも楽しみにしています✨
はたらく細胞２期もBLACKもどちらも面白くて大好きです🥰👍‼️
You do such a good job with these, and I know you’re overwhelmed, but I do hope you’ll keep going with the main series. Cells at Work Black is so dark that I’m even avoiding the reviews.
I learn so much each time I watch one of your videos. Very entertaining and educational! Special shoutout to the commenters who post clarifications on translation: very helpful to my studies in the Japanese language :)
Yaaay, another reacting to Cells at Work video! 😍
Cirrhosis aka bad enough to irreparably damage the only organ that can literally completely regenerate from only a fraction of itself.
Addiction's a hell of a thing.
no, the liver can not regenerate. it can compensate. A lot
18:20 This thing you just said legit made me realize that *hepat* _itis_ is related to *hepat* _ocytes_ , AKA the liver. I hadn't made that connection at all, I hadn't even thought about hepatitis since I got involved with Cells at Work!. Thanks!
"Old red blood cell dies doing what he loved"
Why are the video chapters literal gold I'm gonna cry-
I imagine the liver as a military base, not a hostess club.
Well, they needs some sustances to get rid of alcohol. The fun thing is that when you drink and feel good, your body has a bad time, and when your cells drink to get rid of alcohol they make you suffer the pain.
2:03
To think that our weeb doctor finally has a waifu of his own now.
It's truly a sight, beautiful. One of us. One of us!
12:30 I didn't notice that the background is actually a painting until I see the green screen. As far as paintings go, that's quite a good recreation of your studio!
I cant wait till he reacts to episode 3 lol
And four hahaha
Some serious facemask censoring needed for some of it...
Honestly I just enjoy any cell that has three nucleuses and internal organs that can completely regenerate (my pops worked in regenerative bio for a while so I just picked up fun stuff like this lol)
The facecovering bra hhahahahaha
Multi-use included when buying the facemasks 😂😂😂
This is a very detailed reaction vid😆
Love how you explain things..
The liver is based on a place in Japan, called Kabukicho (more known as Kamurocho because of the Yakuza series) where there's a lot of host/hostess clubs and pubs. Basically a giant red light district.
EDIT: According to Wikipedia it is Kabukicho.
My dad has Hemochromatosis and Non-alcoholic Cirrhosis of the Liver, he was born with it and recently it's been getting worse. But just last month he was able to have his first TIPS surgery, and is starting on the path of getting it handled finally. I wish the show touched a bit more on the liver and different types of illnesses it can have to help show how important of an organ it is. Besides that though, I love this series! Normally after school I watch your reactions to the show, it helped me a lot during my Biology class with the way you explain what the words mean and for what they stand for, so thank you for creating these reaction videos ^^
absence of teeth may indicate that the patient is a meth addict
thank you for making video despite the hardtime you're going through
Part of Japanese corporate culture are after-work drinking parties called _nomikai_ as well as less formal outings with one's boss or other co-workers. It's both a way of blowing off steam and team-building via "nominication," a portmanteau of _nomu_ (drinking) and "communication." Normally you would go to a bar, restaurant, or _izakaya_ (basically a Japanese pub). But if this body is the Black company and the Red Blood Cells are the salarymen, it's not so surprising their cringe-y supervisor chose to take them somewhere more uhhh *risqué* like a hostess club.
Also FYI there are host clubs in Japan where good-looking men tend to their clients, so I imagine that's where the Macrophages and Neutrophils hang out after a hard day of phagocytosing pathogens.
So something I think that's worth mentioning. The use of the word "pissed" in British and American English actually isn't consistent. In the UK it means drunk, in the US it means angry. I assume that some cross usage happens in both countries but that's the primary usage. Here in Australia I think it gets used both ways fairly regularly.
“And that’s why you don’t go to strip clubs, Red Blood Cell”.
I’m dying 😆
I think being a host club is the best way to show the end of the life a red cell.
I learn more from your videos than I ever learned in Biology class
Glossitis (iron deficiency), central cyanosis(heart failure), and thrush (immunosuppression) can be seen on the mouth/tongue. Cranial nerve examination can be done by getting them to stick their tongue out, tongue strength, gag reflex, and palatoglossal arch levels for the bottom cranial nerves for any stroke/bleeding in the lower brainstem/PICA/any blood supply obstruction
This universe has a very interesting implication, not including bacteria and viruses that invade the body as well as accidents, whoever is in charge of the brain is responsible for a number of problems that the cells and the world (Body) go through. Such as smoking, drinking, and risky things that result in injury. This would likely never happen, but a few cells need to go over to the ones controlling the brain and knock some sense into them.
I would have liked to hear a comment on the bit at the end where the body drinks more alcohol. I don't remember exactly what it was called (I think it included the word "tiger"), but it apparently is the idea that taking a small amount of what is making you feel bad will help you recover faster. The anime actually says that there is no scientific basis for it, but I heard from someone that it is actually known to work for some reason. I'm curious what someone more proficient in medicine thinks of this.