Specific (Adaptive) Immunity | Humoral and Cell-Mediated Responses

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  • Опубліковано 2 січ 2025

КОМЕНТАРІ • 172

  • @halqthedarktemplar
    @halqthedarktemplar Рік тому +154

    To add a bit to the cell-mediated response for people reading the comments, the infected cell presents the antigen via the MHC-I (instead of the MHC-II of the APC cells) and the T-killer lymphocyte uses the CD8 receptor for that antigen

    • @naylacalvin2507
      @naylacalvin2507 9 місяців тому +4

      Thank you it was actually helpful

    • @BirhanuChalie-d7n
      @BirhanuChalie-d7n 8 місяців тому +1

      Fantastic lecture and comments.

    • @zizojaezekeom3565
      @zizojaezekeom3565 6 місяців тому +1

      But T8 lymphocytes need T4 lymphocytes so how did T4 lymphocytes get activated if they don't recognize CMH1

    • @Charles-uk6ur
      @Charles-uk6ur 6 місяців тому +2

      @@zizojaezekeom3565 well the macrophage has MHii that presents the antigen,the MHii and is recognised by cd4.while the affected cell has MH i that it presents the antigen with and is recognised by cd8 in short
      macrophage MHii - cd4
      affected cell MHi - cd8

    • @saniyaiqbal
      @saniyaiqbal 4 місяці тому

      actually mhc1 attaches with cd8+ and the antigen which is represented binds with TCR

  • @chefmittens3056
    @chefmittens3056 2 роки тому +73

    This was insanely precise. I love that you follow such a linear path for something involving a lot of steps at once. Seriously thank you thank you thank you. I've watched a lot of good videos on immunity but yours was the only one to truly make it fully understandable.

    • @SiebertScience
      @SiebertScience  2 роки тому +5

      Thanks so much for the kind words! Glad you found it helpful.

    • @MoodSwing-x1s
      @MoodSwing-x1s Рік тому

      Yes, this is so true thank you😊

  • @annguy5563
    @annguy5563 10 місяців тому +7

    This is so amazing, you explain what my 3 hours lectures couldn't in 10 minutes.

  • @charlespolino
    @charlespolino 6 місяців тому +10

    Can't begin to express how excited I am to have come across your channel! 60 slides all explained in one amazing video, and everything just clicked in my head. Thanks Siebert!!

  • @AnaMayorga-x9l
    @AnaMayorga-x9l Місяць тому +2

    You are definably not a good actor, but an amazing teacher. love the ways you show us how things work and every time I am in a new chapter at school I look for your videos before I read the book to have a precise comprehension of what the book talks about.. Once again THANK YOU for your videos

  • @fimpero994
    @fimpero994 7 місяців тому +19

    I've been trying to get my head around this topic for months now and I stumbled across this video, ive never heard it explained so well and so precisely yet in a way so easy to understand. You're an extraordinary teacher, THANKS!

  • @puneet1173
    @puneet1173 3 роки тому +53

    Thank you so much. I have spent hours looking for videos to help me on this topic and now you have made it crystal clear in my head. Please continue to make more videos they help so much

    • @SiebertScience
      @SiebertScience  2 роки тому +3

      Aw, thank you for the comment! Glad it was helpful!

    • @SyenPie
      @SyenPie Рік тому +2

      EXACTLY. This was by far the best video I've found on this topic, presented in such a CLEAR and organized way! This man truly has a gift for teaching.

  • @TiaDimi
    @TiaDimi Рік тому +7

    I have been researching this topic over the past week for an assignment, struggling to find anything as clear and helpful as this video by a mile. This video literally feels like the best video on the whole internet for explaining B cell and T cell functions and specific immune responses in general. The detail is perfect, the whole video flows. Thank you so much, I really appreciate your work!

  • @flygirlkc
    @flygirlkc 3 роки тому +14

    Thank you for the "clear as glass" explanation!

  • @shenglor9913
    @shenglor9913 24 дні тому

    This is the best explanation everrrr. I couldn't piece them all together until now.

  • @wachimingoxd
    @wachimingoxd 3 місяці тому +2

    My god, what a crystal clear explanation for such a convoluted concept, spent the whole afternoon trying to understand the humoral response until I came across your video, many thanks!

  • @tiffany6376
    @tiffany6376 3 роки тому +10

    I got frustrated learning about immune system, but your video is truly a big help for me to understand it better. Hopefully u will continue making new videos cause I gonna be a big fan of your

    • @SiebertScience
      @SiebertScience  3 роки тому +2

      Glad it helped! I plan to keep making more videos!

  • @mulukenm268
    @mulukenm268 10 місяців тому +3

    What an attractive and genius way of presenting!! Please continue doing it for other parts of pathology and physiology. You made the subject matter very edible 😀😀😀

    • @SiebertScience
      @SiebertScience  10 місяців тому +1

      Thanks! I plan to keep making videos 👍🏼

  • @jennyrios9535
    @jennyrios9535 Рік тому +3

    Reviewing my Physiology notes to take my TEAS exam. I looked through so many videos that were either too complex or too simple. This was perfect! Loved the artwork and the clean separation of processes. Thank you!!!

    • @SiebertScience
      @SiebertScience  Рік тому +1

      You're welcome! I'm glad you found it helpful.
      Yeah, it's hard to find resources at the right level for a lot of this stuff.

  • @DestineeMadrigal
    @DestineeMadrigal Рік тому

    Nursing student here! Thank you so much for these videos!! You are a hero!

  • @TheTiss1982
    @TheTiss1982 10 місяців тому

    This man needs a medal for this breakdown! I’m passing this exam! Talk about confidence he just gave me

  • @mondelwane8592
    @mondelwane8592 Рік тому

    I wish you were making videos 4 years ago, my goodness man you are a life saver

  • @zygridollero5479
    @zygridollero5479 Рік тому +2

    Thank you so much for doing this! I was having a hard time reading about this topic on my own. It made so much sense :D

  • @sarahlee3100
    @sarahlee3100 Рік тому +1

    Please continue making these videos. Once I learned about your channel, I can't stop watching them to learn more! Very concise and easy to digest diagrams (they are also very cute) Thank you so much

  • @AnaMishu
    @AnaMishu 9 місяців тому +1

    I always watch your videos before reading a textbook bc most of the time textbook seems very complicated, then I do my quizz assignment with ease

  • @alperbulut1267
    @alperbulut1267 Рік тому

    i didnt had a problem with focusing on your lecture. That's rare for me thank you for the video

  • @johnaghogho2435
    @johnaghogho2435 Місяць тому

    This was every thing I needed... Thanks for being available to help out

  • @ratanraj743
    @ratanraj743 3 роки тому +3

    You are wonderful ... clear and crisp ... wish youtube present u to the needful learners in the manner how our cells present the antigens for betterment of body :)

    • @SiebertScience
      @SiebertScience  3 роки тому

      Thanks! I hope UA-cam listens to your advice, haha! :)

  • @Lilacblossom990
    @Lilacblossom990 10 місяців тому +1

    The best and clearest presentation !

  • @emersongill8501
    @emersongill8501 10 місяців тому

    I'm a very visual learner and the way you drew it all out and separated the different processes! thank you for finally helping my brain understand this topic :) If I get an A on my exam today I can thank you!!

    • @SiebertScience
      @SiebertScience  10 місяців тому

      Glad the videos were helpful. Let me know how you did on your exam!

  • @tajharelstewart5854
    @tajharelstewart5854 2 місяці тому

    Another great video, I love this guy. So smart and explains everything so thoroughly and easy to understand 10/10 teacher

  • @user-ok7vn5eu9j
    @user-ok7vn5eu9j 5 місяців тому

    I watched several videos from other people about this topic, and I was 😵‍💫 until I found yours. Your video is GREAT, and I just subscribed. Thank you !!!

  • @karl_fischer
    @karl_fischer Рік тому

    I have a class test in 4 hours and now I am fully confident that I'll ace that! Thank you.

  • @quesiachagas5446
    @quesiachagas5446 29 днів тому

    I love your videos, and I always study for class with you. THANK YOU!!!

  • @GiftVingula-g5d
    @GiftVingula-g5d 2 місяці тому

    This is amazing explanation ever held

  • @haileyellingson6318
    @haileyellingson6318 2 місяці тому

    So helpful in helping me remember all the cells and their functions! Thank you!

  • @stephaniemiller5165
    @stephaniemiller5165 8 місяців тому

    I
    Spent a week trying to figure this out and u explained it in a few minutes. You are truly a teacher indeed. Can you couple this with the Mac 1 and two? Omg you are good. I have hope now of passing this section of the exam tomorrow!

  • @jo_lenin8990
    @jo_lenin8990 8 місяців тому

    Super cool video. Thank you so much. You make it straight forward, interesting and deep at the same time. Best doctor here!

  • @heatherkrn5200
    @heatherkrn5200 2 роки тому +1

    This is the most helpful video I have seen on the interaction within the adaptive immune system. Thank you for such a clear explanation

  • @Fatma-kl9lp
    @Fatma-kl9lp 3 місяці тому

    You made learning so much fun. Thanks a lot!

  • @ddamme05
    @ddamme05 2 роки тому +2

    I'm not a Bio major but this is probably the best video explaining anything ever. Helps me understand research I'll have to read for my extra-credit assignment. Thanks!

    • @SiebertScience
      @SiebertScience  2 роки тому +1

      Best video explaining anything ever???
      What a great compliment! I appreciate it!

  • @hollyweselowski7442
    @hollyweselowski7442 2 роки тому +1

    thorough and helpful, im an NP student and this was SUPER helpful !

  • @darianleduc
    @darianleduc Рік тому

    Thank you so much! Adding the etymology of the cell and biochem names is super helpful

  • @allround8771
    @allround8771 3 роки тому +3

    I've been watching a couple of videos on the Immune System and I could easily admit that you're the Phil Jackson of Immunology.
    Well, Phil Jackson with a touch of DiCaprio (nice fake acting lol). You've mastered the act of transferring knowledge.
    Thank you!!!

    • @SiebertScience
      @SiebertScience  3 роки тому +1

      Hey, my students tell me my acting is improving! But they’re probably just being nice...
      Thanks for the comment!

  • @jodifarias9757
    @jodifarias9757 5 місяців тому

    So clear and beautifully illustrated. Thanks

  • @ajaklual1689
    @ajaklual1689 3 місяці тому

    You are a great teacher 😊😊😊

  • @laurenbaron6820
    @laurenbaron6820 2 роки тому +1

    Thank you so much! Very helpful video. Love the pictures made it much more clear :)

  • @carlapaperdoll
    @carlapaperdoll 8 місяців тому

    Bless you! Please continue doing what you're doing! You're an angel

  • @Jarh9999
    @Jarh9999 2 роки тому +1

    thank you sooooooooo much this clicks so well now

  • @cbri1621
    @cbri1621 Рік тому

    Your videos have single handedly taught me all of the systems that we need to know for the MCAT! I never took anatomy as its not required for us and when I started studying I had regrets on not taking it, but man your videos on the immune system, digestive, respiratory, circulatory and kidneys have literally taught me everything!!! Your videos are so well put together and so easy to follow I hope UA-cam pays you a million dollars a year for your services :)
    Question about the immune system: So what is the difference between MHC-II and MHC-I? Are MHC-II's only present on macrophages?
    Seriously thank you x 1000 and I hope to use your videos throughout medical school once I make it there :)

  • @chrissvitreoushumour
    @chrissvitreoushumour Рік тому

    awesome explanation. you connected the processes of cell-mediated and humoral immunity really well

  • @sadraaghanoor
    @sadraaghanoor 2 місяці тому

    I would like to thank you for your clear explanation. ❤

  • @chrisandarianna1583
    @chrisandarianna1583 2 місяці тому

    Bro, THAAAAAANK YOU! I was not understanding this until I saw your video.

  • @hamzaha.al-quaid2441
    @hamzaha.al-quaid2441 2 роки тому +1

    Really awesome big picture video. Thank you🙏🧬

  • @marthaschurr7827
    @marthaschurr7827 Рік тому

    Great video, and such beautiful visuals

  • @mollygrigg7005
    @mollygrigg7005 9 місяців тому

    I watched the lymphatic system video and now this … and I want to watch the blood one next. For the very first time I’m finding human body systems fascinating. Never had such a great teacher before. I might have gone into medicine if I had had videos like this in my younger life!
    Now I’m going to use them to teach my kids!

    • @SiebertScience
      @SiebertScience  9 місяців тому

      Aw, thanks for the kind words! Best of luck with homeschooling anatomy this year!

  • @dinabereket569
    @dinabereket569 23 дні тому

    Thank you for what you do ! really helpful

  • @yhwhspirit
    @yhwhspirit 6 місяців тому

    I thank God for helping me find this channel 🙏🙏 immunology best explanation ❤

  • @khalidabdulfattahmutwally9286

    Extremely beautiful and beneficial. I love that so much.. please continue

  • @elle3947
    @elle3947 2 роки тому +3

    Took me so long to understand until this short video , so clear :) thanks

  • @sagaranilkumar8619
    @sagaranilkumar8619 2 роки тому

    Oh thanku so much for that wonderful class helped me to understand the topic very much... plz keep going and post more videos..

  • @ilaly8347
    @ilaly8347 6 місяців тому

    You’re literally the best!!! I don’t know why you don’t do biochemistry😭

    • @SiebertScience
      @SiebertScience  6 місяців тому

      I’d love to do biochemistry someday. But this isn’t my job…I do all this stuff in my spare time, so I’m pretty limited in how much content I can make.

  • @v.2435
    @v.2435 Рік тому

    This is so concise, Thank a lot Prof. !!!

  • @evamaryanti800
    @evamaryanti800 11 місяців тому

    Not so convincing coughing, but the lecture was amazinggggg. Thanks!

    • @SiebertScience
      @SiebertScience  11 місяців тому

      So you’re saying I shouldn’t quit UA-cam to become an actor??? ;)

    • @johnaghogho2435
      @johnaghogho2435 Місяць тому

      Lol no ...we still need you ​@@SiebertScience

  • @akeminnocentosagie5901
    @akeminnocentosagie5901 Рік тому

    You have definitely help and educate me so so much with your videos. You are the best with the You analyses and make it look very simple to understand. Thank u so much.

  • @milliecroft1200
    @milliecroft1200 9 місяців тому

    I dont think ive ever commented on a youtube video in my life, but this was so helpful i almost did a backflip out of joy, thanks !!!!!

  • @pulkitverma8104
    @pulkitverma8104 Рік тому

    Brother one of the finest video on this topic.....you got my respect 👍🏻🤝🏻

  • @jenniferthomas6592
    @jenniferthomas6592 Рік тому

    This was super helpful! Thank you!

  • @arnabray3662
    @arnabray3662 2 роки тому

    Thank you so much for such amazing explanation. Definitely gonna nail this topic tomorrow

  • @mohammedshamboul3145
    @mohammedshamboul3145 Рік тому

    Thank you
    You are good medical teacher I watch in youtube

  • @celinaleal7692
    @celinaleal7692 8 місяців тому

    Love your videos! I'm doing biomed and some concepts I just cant' understand until you explain it. Also, omg I love Cells at Work too!!

  • @eman.hasann3335
    @eman.hasann3335 Рік тому

    U r one of the best youtuberrrr❤❤❤❤❤❤❤

  • @LanaNY0114
    @LanaNY0114 6 місяців тому

    THANK YOU SO MUCH 🙌🏼🙌🏼🙌🏼🙌🏼🙌🏼

  • @rajabumlaluko2897
    @rajabumlaluko2897 Рік тому

    I found it more helpful and easy to understand

  • @ethancraeynest4183
    @ethancraeynest4183 Рік тому

    very clear and specific video, just hoped you would take about the types of interferones and the "component system" too. This would have helped to be even more complete. Maybe talking about the NK-cells too but overall very very good video

    • @martashenker
      @martashenker Рік тому

      NK cells are part of the innate immune system, that's why they are not being discussed here

  • @lamarjr001
    @lamarjr001 Рік тому

    You’re the best!!🏆🔥

  • @taylorguarino1555
    @taylorguarino1555 Рік тому

    Thank you so much for this amazing video

  • @AlaaSalah-jc1gl
    @AlaaSalah-jc1gl 12 днів тому

    U are amazing, man ❤

  • @aggelikinakou_
    @aggelikinakou_ 2 роки тому +1

    oh my god, thank you so much for this video, immunology is driving me crazy

  • @samanthaagneslumapas8479
    @samanthaagneslumapas8479 Рік тому

    Big help 🎉 thank you!

  • @kimmagri181
    @kimmagri181 2 роки тому +1

    Very helpful ! Thank you so much :)

  • @trinityg8511
    @trinityg8511 11 місяців тому

    the best video to explain this. I really wanted a clear cut, step by step demonstration and this is incredibly helpful. thankyou!

  • @BirhanuChalie-d7n
    @BirhanuChalie-d7n 8 місяців тому

    Fantastic lecture and comments

  • @vectorie6195
    @vectorie6195 2 роки тому +1

    Thank you so much

  • @bouthainagarna7680
    @bouthainagarna7680 5 місяців тому

    Thank you so much that was very helpful

  • @jonnymercy4528
    @jonnymercy4528 8 місяців тому

    best guide ever!

  • @AlaaSalah-jc1gl
    @AlaaSalah-jc1gl 12 днів тому

    I really have fun with you 😂 I've repeated the part of " wanting for you " many times😂❤

  • @cortneyellyn3233
    @cortneyellyn3233 6 місяців тому

    When you're taking a 6 week online accelerated A&P 2 class before nursing school starts-- you're freaking out and then you find Siebert Science. I may pass now. THANK YOU. lol

  • @chibuikeolachukwu1800
    @chibuikeolachukwu1800 24 дні тому

    Am i the only one. That thinks this man is ADORABLE 🥰🥰🥰🥰🥰🥰

  • @lol-i2d9e
    @lol-i2d9e Рік тому

    thanks heaps for this video!

  • @Heh18287
    @Heh18287 7 місяців тому

    thanks you for this AMAZING explanation, and you should definitely be an actor😂

  • @32stillgrowingup
    @32stillgrowingup 2 місяці тому

    THANK YOU THANK YOU THANK YOU!!

  • @carolinew1616
    @carolinew1616 Рік тому

    THANK YOU! 🎉🎉

  • @sookieseestruth7573
    @sookieseestruth7573 10 місяців тому

    This was the bomb. Thank you

  • @anabutler5675
    @anabutler5675 5 місяців тому

    YOU ARE THE BEST!!!!

  • @mangajunction8762
    @mangajunction8762 2 роки тому +2

    This is good ✨

  • @grrrrr219
    @grrrrr219 2 роки тому

    hataraku saibou in the background! It's a good show focusing on body immunology ! 😄

    • @SiebertScience
      @SiebertScience  2 роки тому +1

      I was hoping some people would notice that! Great show!

  • @TP-mv6en
    @TP-mv6en 2 роки тому

    This is a great video thanks so much for making it

  • @Ahmad_Fawaz
    @Ahmad_Fawaz 2 роки тому +1

    Can you make vd about the non-specific?

  • @파이브-t6w
    @파이브-t6w 4 місяці тому

    I wish you were my biology teacher

  • @suzankhaled3641
    @suzankhaled3641 3 місяці тому

    That is amazing specially the fake cough 😂❤

  • @sandyable
    @sandyable 2 роки тому

    so far your videos have been very helpful:) thank you for making it easier for us. although I didn't believe you were sick :x

  • @NappyZoeRebel
    @NappyZoeRebel 8 місяців тому

    Great video!!!

  • @JessicaDejesus60
    @JessicaDejesus60 Рік тому

    wow thank you so much!!

  • @rimikabanerjeesadhu9741
    @rimikabanerjeesadhu9741 3 місяці тому

    Explained well......